ALLIANCE SELECT INVESTOR SERIES FUND INC
NSAR-B, EX-99, 2000-12-29
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Report of Independent Accountants

To the Board of Directors and Shareholders of
Alliance Select Investor Series, Inc.  - Technology Portfolio

In planning and performing our audit of the financial statements of Alliance
Select Investor Series, Inc. - Technology Portfolio (the "Fund") for the year
ended October 31, 2000, we considered its internal control, including control
activities for safeguarding securities, in order to determine our auditing
procedures for the purpose of expressing our opinion on the financial
statements and to comply with the requirements of Form N-SAR, not to provide
assurance on internal control.

The management of the Fund is responsible for establishing and maintaining
internal control.  In fulfilling this responsibility, estimates and
judgements by management are required to assess the expected benefits and
related costs of controls.  Generally, controls that are relevant to an audit
pertain to the entity's objective of preparing financial statements for
external purposes that are fairly presented in conformity with generally
accepted accounting principles.  Those controls include the safeguarding of
assets against unauthorized acquisition, use or disposition.

Because of inherent limitations in internal control, error or fraud may occur
and not be detected.  Also, projection of any evaluation of internal control
to future periods is subject to the risk that it may become inadequate because
of changes in conditions or that the effectiveness of the design and operation
may deteriorate.

Our consideration of internal control would not necessarily disclose all
matters in internal control that might be material weaknesses under standards
established by the American Institute of Certified Public Accountants.
A material weakness is a condition in which the design or operation of one or
more of the internal control components does not reduce to a relatively low
level the risk that misstatements caused by error or fraud in amounts that
would be material in relation to the financial statements being audited may
occur and not be detected within a timely period by employees in the normal
course of performing their assigned functions.  However, we noted no matters
involving internal control and its operation, including controls for
safeguarding securities, that we consider to be material weaknesses as defined
above as of October 31, 2000.

This report is intended solely for the information and use of management and
the Board of Directors of the Fund and the Securities and Exchange Commission,
and is not intended to be and should not be used by anyone other than these
specified parties.


PricewaterhouseCoopers LLP
New York, NY 10036
December 18, 2000



















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