PRAXIS PHARMACEUTICALS INC/CN
10SB12G, 1999-12-23
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                     U.S. Securities and Exchange Commission
                             Washington, D.C. 20549


                                   FORM 10-SB



              GENERAL FORM FOR REGISTRATION OF SECURITIES OF SMALL
                                BUSINESS ISSUERS
        UNDER SECTION 12(B) OR (G) OF THE SECURITIES EXCHANGE ACT OF 1934



                           PRAXIS PHARMACEUTICALS INC.
                 (Name of Small Business Issuer in its charter)


            UTAH                                        87-0393257
(State or other jurisdiction of             (I.R.S. Employer Identification No.)
 incorporation or organization)



    595 HORNBY STREET, SUITE 600, VANCOUVER, BRITISH COLUMBIA V6C 1A4 CANADA
      (Address of principal executive offices)                (Zip Code)


                    Issuer's telephone number: (604) 646-5614


        Securities to be registered under Section 12(b) of the Act: NONE


           Securities to be registered under Section 12(g) of the Act:

                          COMMON STOCK, $.001 PAR VALUE
                                (Title of class)




Exhibit index on page 14.                                   Page 1 of ____ pages




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PART I

ITEM 1.           DESCRIPTION OF BUSINESS.

         Praxis  Pharmaceuticals  Inc. ("Praxis" or the "Company") was formed in
response to an apparent market  opportunity in the  pharmaceutical  industry for
small  molecular  agents  capable  of  moderating  inflammatory  responses.  The
founding  individuals   recognized  several  significant  diseases,   which  are
inadequately served by current therapies, as providing this opportunity.  Praxis
is a startup company, which commenced operations in July 1997. Its mission is to
develop a unique  panel of  therapeutics  based on  carbohydrate  chemistry.  To
achieve that  mission,  Praxis plans to acquire  licenses for agents to apply in
new therapeutic  categories and to develop new drugs  internally.  The drugs are
intended to be used in the control of  inflammation  in a range of  indications,
such  as skin  conditions  to  autoimmune  diseases.  The  technology  also  has
applicability in the cosmetic and nutraceutical  markets and agents for wrinkles
and other conditions are being developed for these markets.

BACKGROUND AND CORPORATE STRUCTURE

         Praxis  Pharmaceuticals,  Inc. was  incorporated on June 20, 1997 under
the laws of the  State of  Nevada.  In June  1998,  Praxis-Nevada  engaged  in a
reverse acquisition  transaction with Micronetics,  Inc., a company incorporated
in Utah on December 31, 1981,  where the  shareholders of  Praxis-Nevada  gained
control  over   Micronetics.   Micronetics  then  changed  its  name  to  Praxis
Pharmaceuticals   Inc.   A   wholly   owned   Australian   subsidiary,    Praxis
Pharmaceuticals Australia Pty. Ltd. (ACN 082 811 630) ("Praxis-Australia"),  was
formed in June 1998 as a private company.

         In October 1999 an equity  investment  was made in Praxis  Australia by
Rothschild  Bioscience  Managers Ltd., which reduced Praxis' equity ownership to
35%.

PATENTS AND LICENSE RIGHTS

         The  Company  has  obtained  exclusive  licenses  to  exploit  and  use
intellectual  property  possessed by the Australian  National  University in the
area of phosphosugars and their analogues as anti-inflammatory  agents,  covered
by  the  University's  patents  (including  USA  5506210,  European  89909685.3,
International WO90/01938 and Australia PO3098/96).

         Anutech Pty Limited,  the commercial  subsidiary of Australian National
University,  originally  granted a license to the Company in October 1997.  This
earlier  agreement was  superseded by an agreement  dated October 14, 1999.  The
Company's  exclusive  worldwide  license pertains to the use of phosphosugars as
nutraceuticals (foods that provide medicinal or health benefits),  complementary
medicines,   or  cosmetics.   The  license  specifically  excludes  the  use  of
phosphosugars  as prescription  therapeutics  and topical  application for wound
care. As  consideration  for the license,  Anutech is to receive a 4% royalty on
net sales of  products,  50% of all  royalty  income  on net  sales of  products
received from sublicensees, and 15% of all sublicense fees.

         Anutech has granted Praxis-Australia the exclusive worldwide license to
the use of phosphosugars as prescription  therapeutics and specifically excludes
the uses  granted  to the  Company.  Anutech  is to  receive  2% of all  amounts
received by  Praxis-Australia or any sublicensee in connection with the licensed
intellectual property or related products.

         In addition to the licenses  described  above,  Praxis owns two patents
that  relate to agents for use in  immunosuppression  and  transplant  rejection
(US5691346  and US  5837709).  Praxis  believes  that patent  protection  of its
technologies,  processes and products is important to its future operations. The
success of Praxis's  proposed products might depend, in part, upon the Company's
ability to obtain  patent  protection.  Praxis  intends  to  enforce  its patent
position and  intellectual  property  rights  vigorously.  The cost of enforcing
Praxis's patent rights in lawsuits,  if necessary,  may be significant and could
interfere with Praxis's  operations.  Although Praxis intends to file additional
patent applications, as management believes appropriate, with respect to any new
products  or  technological  developments,  no  assurance  can be given that any
additional  patents will be issued or, if issued,  will be of commercial benefit
to Praxis. In addition,  it is impossible to anticipate the breadth or degree of
protection that any

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<PAGE>

such  patents  may  afford.  To the  extent  that  Praxis  relies on  unpatented
proprietary  technology,  no  assurance  can  be  given  that  others  will  not
independently develop or obtain substantially  equivalent or superior technology
or  otherwise  gain access to Praxis'  trade  secrets,  that any  obligation  of
confidentiality  will be  honored  or that  Praxis  will be able to  effectively
protect its rights to proprietary technology. Further, no assurance can be given
that any products  developed  by Praxis will not infringe  patents held by third
parties  or that,  in such  case,  licenses  from such  third  parties  would be
available on commercially acceptable terms, if at all.

COMPANY DEVELOPMENT

         It is envisioned that the Company will develop in stages:

         o   Research and Development
         o   Clinical Trials
         o   Commercialization

         Praxis'  business plan envisions the first two stages taking place over
the next three-year period. The Company has engaged in private placements of its
stock  to fund  research  and  development  activities.  Additional  funding  of
approximately  $6,000,000 is being sought by the Company to enable it to develop
its  intellectual  property  portfolio and to engage in early clinical trials of
its proposed  products.  Clinical trial activities will be necessary to generate
evidence  of  efficacy  in order to attract  alliance  partners.  An alliance in
pharmaceutical terms is the joint effort of a major pharmaceutical company and a
smaller  "junior"  drug  developer  who has the idea and the  research,  but not
sufficient  capital  to  continue  this to the  next and  most  critical  phase.
Management  believes that the future  viability of Praxis relies  greatly on the
opportunity  to gain the  support,  for  mutual  benefit,  of one of the  larger
worldwide drug houses.  This may be particularly  appropriate to the development
of  formulations  for  topical or ocular  delivery  of Praxis  drugs.  Strategic
alliances with such companies  will be  investigated  as a matter of priority by
Praxis.

         The Company entered into a Research,  Development and Licence Agreement
with Fairchild International Inc., an affiliate, dated as of May 11, 1999, which
closed  September  30,  1999.  Under  that  agreement,   Fairchild  obtained  an
exclusive,  worldwide  license to make,  use, and sell  products  and  processes
developed by Praxis relating to arthritis and dermal  wrinkles in  consideration
for 2,600,000 shares of Fairchild common stock and $250,000. A first installment
of $62,500 was paid on October 1, 1999.  Quarterly payments of $50,000 are to be
made beginning  January 1, 2000,  with a final payment of $37,500 due October 1,
2000. Praxis agreed to conduct certain research projects  commencing  October 1,
1999. Any new intellectual property developed as a result of that research is to
be included  as part of the  licensed  technology  and  licensed  to  Fairchild.
Fairchild is  authorized  to grant  sublicenses  and/or assign the license to an
affiliate.  Praxis is to be paid 35% of any consideration  received by Fairchild
from the sale of a licensed  product or the granting of a  sublicense,  less the
$250,000 and any other  development  costs,  manufacturing and production costs,
and marketing and selling costs.

         In October  1999,  an equity  investment  of $1.4 million by Rothschild
Bioscience  Managers Limited,  of Melbourne,  Victoria,  was accepted by Praxis.
This  investment  was solely for the purpose of research  and  development  into
phosphosugar-based  anti-inflammatory  agents for  registered  therapeutic  use.
Praxis retains a 35% equity in Praxis Pharmaceuticals Australia Pty Ltd.

         It is expected that the  profitability  and financial  viability of the
Company will ultimately  rest with the corporate  alliances that will be entered
into at this stage of fund raising.  As noted above, the benefits of a correctly
structured  alliance  can be enormous  for both  parties  involved.  The Company
expects  to incur  significant  operating  losses  over at least the next  three
years. There is every likelihood that these losses may increase in the future as
the research  and  development  and  clinical  trials  continue.  The  Company's
profitability  will ultimately  depend upon its ability to reach development and
obtain  regulatory  approval for its  products,  and to enter into  alliances to
develop,  manufacture  and market the products.  There is no guarantee  that the
Company will ever be profitable.

         Praxis'  near-term  goals are to raise the funds necessary for the next
five  years  of  company  research  and  development  activities  through  share
offerings  and cash flow  derived  from  sales and or  licensing  agreements  on
cosmetic products;  invest in a dedicated  research facility and personnel;  and
generate  pre-clinical and early clinical  results for the lead compounds.  Over
the long term, its goal is to develop strategic alliances with established

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<PAGE>

pharmaceutical  companies in order to conduct large scale,  late stage  clinical
trials and to market approved therapeutics.

RESEARCH AND DEVELOPMENT

         During  the  fiscal  years  ended May 31,  1999 and 1998,  the  Company
incurred $92,456 and $50,016 in research costs, respectively.  Through the three
months  ended  August 31,  1999,  the  Company  spent  $22,352 on  research  and
development.

         In  general  terms  the  research  and  development   process  for  the
pharmaceutical agents is as follows:

         o   Secure source of drug substance

         o   Development of validated analytical assays for purity and stability

         o   Development  of validated  analytical  assays for  detection of the
             drug substance in plasma

         o   Formulation studies to provide a stable formulation for human use

         o   Full  toxicology  program  in  accord  with  current  international
             guidelines

         o   Preparation of clinical trial material

         This process is expected to cost  approximately  $1,000,000 to complete
and allows  commencement  of clinical  trials.  The Company intends to focus its
efforts on the following  conditions/diseases:  psoriasis,  surgical  adhesions,
ocular  inflammation,  rheumatoid  arthritis,  and wrinkles.  Specific strategic
commercial   targets  are  as  follows:   Psoriasis  -  Develop  optimal  dermal
formulation  and enter  early  stage  clinical  trials by second  quarter  2001.
Following  the early stage trials  (early Phase II), the Company plans to form a
strategic alliance with large pharmaceutical company to advance clinical trials.

         o   Surgical  adhesions - Develop a data package  which will be used to
             enter into an agreement  with an appropriate  large  pharmaceutical
             company to receive  milestone  and  royalty  payments  for  further
             development.  The  goal is to have  such a data  package  by  first
             quarter 2001.

         o   Ocular  inflammation - Develop a data package which will be used to
             enter  into an  agreement  with  an  appropriate  large  ophthalmic
             specialist  pharmaceutical company to receive milestone and royalty
             payments for further  development.  The goal is to have such a data
             package by first quarter 2001.

         o   Rheumatoid  arthritis - Develop optimal oral  formulation and enter
             early stage  clinical  trials by first quarter 2002.  Following the
             early stage trials  (early  Phase II), the Company  plans to form a
             strategic alliance with a large  pharmaceutical  company to advance
             clinical trials.

         o   Wrinkles - A dermal  product is to be finalized  by second  quarter
             2000 and initial trials will begin in fourth quarter.  An agreement
             has been entered into with a cosmetic  marketing  company that will
             be  responsible  for  production  and sales of the product in early
             2001.

         Although  several drugs have been  developed by various  pharmaceutical
companies to treat the diseases targeted by Praxis,  relatively limited research
has been  conducted in the  development  of  carbohydrate  based on M6P receptor
targeted   pharmaceutical   products.   Although  Praxis  has   demonstrated  in
pre-clinical studies that its carbohydrate compounds may have applicability in a
broad range of  diseases,  clinical  studies are yet to be  performed to confirm
these findings.  The Company's  proposed  products are in the early  development
stage, require significant further research, development, testing and regulatory
clearances,  and are subject to the risks of failure inherent in the development
of  products  based  on  innovative   technologies.   These  risks  include  the
possibilities  that  any or all of the  proposed  products  may be  found  to be
ineffective  or toxic,  or otherwise  may fail to receive  necessary  regulatory
clearances;  that the proposed products, although effective, may be uneconomical
to market; or that third parties may market superior or equivalent products. Due
to the extended testing and regulatory  review process required before marketing
clearance can be obtained, Praxis does not expect to be able to realize revenues
from the sale of any drugs in the near term.

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<PAGE>

GOVERNMENT REGULATION

         The  production and marketing of Praxis's  pharmaceutical  products are
subject to  regulation  for  safety,  efficacy  and  quality.  The Food and Drug
Administration  approval procedure involves  completion of certain  pre-clinical
and  manufacturing/stability  studies and the submission of the results of these
studies to the FDA in an  Investigational  New Drug (IND) application in support
of performing  clinical trials. IND allowance is then followed by performance of
human clinical  trials and additional  pre-clinical  and  manufacturing  quality
control studies supporting safety,  efficacy and manufacturing  quality control.
The information  developed under the IND is compiled into a New Drug Application
and  submitted  to FDA for  approval  to market.  The  sequence  of events is as
follows:

         o   PRE-CLINICAL  STUDIES  involve  laboratory  evaluation  of  product
             characteristics  and  animal  studies to assess  the  efficacy  and
             safety of the  product.  These tests take on the average  three and
             one-half years.

         o   AN IND IS FILED  with  the FDA to  begin  testing  the  product  on
             people. The IND becomes effective if the FDA does not disapprove it
             within 30 days.  However,  any FDA  comments or  questions  must be
             answered to the  satisfaction  of the FDA before  initial  clinical
             testing can begin. In some instances,  this process could result in
             substantial delay and expense

         o   PHASEI  trials  consist of testing of the product in a small number
             of normal  volunteers,  primarily for safety.  These trials take on
             the average one year.

         o   In PHASE II, in addition to safety,  the efficacy of the product is
             evaluated in a small patient population. This typically takes about
             two years.

         o   PHASEIII trials typically  involve  multicenter  testing for safety
             and  clinical  efficacy  in an expanded  population  of patients at
             geographically   dispersed   test  sites.   A  clinical   plan,  or
             "protocol,"   accompanied  by  the  approval  of  the  institutions
             participating in the trials,  must be submitted to the FDA prior to
             commencement  of  each  clinical  trial.  The  FDA  may  order  the
             temporary or permanent  discontinuation  of a clinical trial at any
             time if adverse  events  that  endanger  patients in the trials are
             observed. These trials take on the average three years.

         o   NEW DRUG  APPLICATION  (NDA) is  prepared  and filed  with the FDA,
             containing  an  analysis  of the  results of the  pre-clinical  and
             clinical studies on the new drug.  Following  extensive review, the
             FDA may grant marketing  approval,  require  additional  testing or
             information  or deny the  application.  The average NDA review time
             for new drugs is roughly two and one-half years.

         o   PHASEIV  clinical  trials may be requested  to be  performed  after
             marketing approval to resolve any lingering questions.

         Continued compliance with all FDA requirements and the conditions in an
approved application,  including product  specifications,  manufacturing process
and labeling requirements, are necessary for all products. Failure to comply, or
the  occurrence of  unanticipated  adverse events during  commercial  marketing,
could  lead  to  the  need  for  labeling  changes,   product  recall,  seizure,
injunctions  against  distribution or other  FDA-initiated  action,  which could
delay further marketing until the products are brought into compliance.

         The NDA itself is a complicated and detailed  document and must include
the results of extensive animal,  clinical and other testing,  the cost of which
is substantial.  Although the FDA is required to review  applications within 180
days of filing,  in the process of  reviewing  applications  the FDA  frequently
requests  that  additional  information  be  submitted  and  starts  the 180 day
regulatory  review  period anew when the  requested  additional  information  is
submitted.   The  effect  of  such  requests  and  subsequent   submissions  can
significantly  extend  the  time  for the NDA  review  process.  Until an NDA is
actually approved,  no assurance can be given that the information requested and
submitted will be considered adequate by the FDA to justify approval.

         Whether or not FDA approval has been obtained, approval of a product by
a comparable  regulatory  authority  must be obtained in most foreign  countries
prior to the  commencement  of  marketing  of the product in that  country.  The
approval  procedure  varies from  country to country and may involve  additional
testing,  and the time  required may differ from that required for FDA approval.
Although  some  procedures  for  unified  filings  exist  for  certain  European
countries, in general each country has its own procedure and requirements,  many
of which are time consuming and expensive. Thus, substantial delays in obtaining
required approvals from foreign regulatory

                                        5
<PAGE>


authorities may be encountered after the relevant  applications are filed. After
such  approvals  are  obtained,  further  delays may be  encountered  before the
products become commercially available.

         No assurance  can be given that any required FDA or other  governmental
approval  will be granted or, if granted,  will not be  withdrawn.  Governmental
regulation may prevent or substantially delay the marketing of Praxis's proposed
products  and cause Praxis to undertake  costly  procedures.  This may furnish a
competitive advantage to the more substantially capitalized companies with which
Praxis  plans to  compete.  In  addition,  the  extent  of  potentially  adverse
government  regulations  that may arise  from  future  administrative  action or
legislation cannot be predicted.

COMPETITION

         Praxis  faces  significant  competition  in the area of  pharmaceutical
research.  Due to the  Company's  small size, it can be assumed that most if not
all of its competitors have  significantly  greater  financial,  technical,  and
other resources. These competitors may be able to respond more quickly to new or
emerging  technologies  than Praxis can.  Also,  the Company's  competitors  and
potential  competitors  have greater name  recognition and ability to enter into
strategic  partnerships  to engage in new research and development  efforts.  To
compete,  Praxis may be forced to narrow its  research  and  development  focus,
reducing its likelihood for success.

EMPLOYEES

         As of December 1, 1999,  the  Company had 6 full-time  employees,  1 of
which was an officer of the Company, Dr. William Cowden.

         The Company's opportunity for success depends largely upon the efforts,
abilities,  and decision-making of its executive  officers.  The loss any of the
Company's key personnel could, to varying degrees, have an adverse effect on its
operations  and research and  development  efforts.  The loss of any one of them
would have a material adverse affect on the Company.

         The Company does not currently maintain "key-man" life insurance on any
of its  executive  officers,  and there is no contract in place  assuring  their
services  for any  length of time.  Within a  reasonable  period  of time  after
sufficient funds are available,  it is the Company's intention to develop a plan
to purchase key-man life insurance for one or more key persons, with the Company
designated as the beneficiary,  and enter into employment  contacts with its key
executives.  There is no assurance that the services of any member of management
will remain  available  to the Company for any period of time,  that the Company
will be able to enter into employment  contracts with any of its management,  or
that any of the Company's plans to reduce  dependency upon key personnel will be
successfully   implemented.   The  Company  plans  to  have  industry   standard
non-compete and non-disclosure agreements with all of its employees.


ITEM 2.           MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION.

         The  following  discussion  of the  financial  condition and results of
operations  for  Praxis  should  be read in  conjunction  with the  accompanying
financial statements and related footnotes.

GENERAL

         The Company's  business is the  development  and  commercialization  of
drugs and  nutraceuticals  designed to prevent  inflammation and their sequelae,
and the development of cosmetics for skin  conditions.  To date,  Praxis has not
generated any revenues from product sales,  royalties or license fees. Effective
September 30, 1999,  the Company  entered into a sublicensing  arrangement  with
Fairchild  International  Corp.  for  the  development  of a  nutraceutical  and
cosmetic  agent.  In  exchange  for this  sublicense,  the Company is to receive
$250,000 as  reimbursement  for research and development  costs it has incurred.
Praxis plans to develop novel drugs and cosmetics,  and to  commercialize  these
products through the formation of partnerships,  strategic alliances and license
agreements with pharmaceutical and cosmetic companies.

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<PAGE>

         It is expected that the  profitability  and financial  viability of the
Company will  ultimately  rest with the corporate  alliances it can obtain.  The
Company  expects to incur  significant  operating  losses over at least the next
three  years.  It is likely that these  losses may increase in the future as the
research  and   development  and  clinical   trials   continue.   The  Company's
profitability  will ultimately  depend upon its ability to reach development and
obtain  regulatory  approval for its  products,  and to enter into  alliances to
develop,  manufacture  and market the products.  There is no guarantee  that the
Company will ever be profitable.

         Praxis'  near-term  goals are to raise the funds necessary for the next
five  years  of  company  research  and  development  activities  through  share
offerings  and cash flow  derived  from  sales and or  licensing  agreements  on
cosmetic products;  invest in a dedicated  research facility and personnel;  and
generate  pre-clinical and early clinical  results for the lead compounds.  Over
the long  term,  its goal is to develop  strategic  alliances  with  established
pharmaceutical  companies in order to conduct large scale,  late stage  clinical
trials and to market approved therapeutics.

RESULTS OF OPERATIONS

         THREE  MONTHS  ENDED  AUGUST 31, 1999  COMPARED TO THREE  MONTHS  ENDED
AUGUST 31, 1998. The Company continues to incur losses from operations.  The net
loss for the three  months  ended  August 31,  1999 was  $92,655 as  compared to
$40,832 during the comparable  three-month  period in 1998. The most significant
increases in expenses  occurred in promotion  and travel (a 229%  increase)  and
related  party  administration   charges  (a  1946%  increase).   Related  party
administration  charges included consulting fees paid to an officer and director
of the Company ($25,472).  Also included were amounts charged by Alexander Cox &
Co., a company controlled by David Stadnyk, for the Company's proportional share
of office rent and administrative  services resulting from the sharing of office
facilities with other companies controlled or managed by Alexander Cox & Co.

         YEAR ENDED MAY 31, 1999 COMPARED TO PERIOD ENDED MAY 31, 1998.  For the
year ended May 31,  1999,  the net loss was  $530,574  as  compared to a loss of
$68,296 for the period from inception at June 20, 1997 to May 31, 1998.
 Administration expenses increased from $15,460 in 1998 to $393,118 in 1999. The
most  significant  component of these  expenses in 1999 was  consulting  fees of
$253,358.  Most of these  consulting  fees were paid through the issuance of the
Company's  common stock for public  relations and other  services.  Research and
development costs increased by $42,440 from $50,016 in 1998 to $ 92,456 in 1999,
an 84.9%  increase.  1999 costs  increased  due to the  hiring of a director  of
research and development and to increased  pre-clinical study costs and internal
research  and  development  efforts.  The  Company  expects  that  research  and
development  costs will  continue  to  increase  in 1999,  reflecting  increased
pre-clinical and clinical testing of its products.

LIQUIDITY AND CAPITAL RESOURCES

         Since inception,  the primary source of funding for Praxis'  operations
has been the private sale of its  securities.  Through May 31, 1999, the Company
issued  common stock for cash of $188,725  and  services of  $249,208,  and sold
$50,000 of convertible debentures.

         At May 31, 1999, the Company's working capital  deficiency was $56,397,
as compared to the deficiency of $119,296 at May 31, 1998. Of the liabilities at
May 31, 1999,  $153,082 was owed to Alexander Cox & Co., an affiliate,  for sums
advanced for  operations.  At August 31, 1999,  the working  capital  deficiency
increased to $149,052 due to the  depletion  of cash for  operations  during the
three months then ended and the increase in accounts payable.

         Until such time as the  Company  obtains  agreements  with  third-party
licensees or partners to provide funding for the Company's  anticipated research
and development activities, the Company will be dependent upon proceeds from the
sale of  securities.  Further,  substantial  funds will be  required  before the
Company is able to generate revenues sufficient to support its operations. There
is no assurance that the Company will be able to obtain such additional funds on
favorable  terms, if at all. The Company's  inability to raise  sufficient funds
could  require  it to  delay,  scale  back or  eliminate  certain  research  and
development programs.

         The  report of the  Company's  independent  auditors  on the  financial
statements for the year ended May 31, 1999,  includes an  explanatory  paragraph
relating  to the  uncertainty  of the  Company's  ability to continue as a going

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<PAGE>

concern.  Praxis  has  suffered  losses  from  operations,  requires  additional
financing, and needs to continue the development of its products. Ultimately the
Company  needs  to  generate   revenues  and  successfully   attain   profitable
operations. These factors raise substantial doubt about the Company's ability to
continue as a going  concern.  There can be no assurance that it will be able to
develop a commercially viable product.  Even if the Company were able to develop
a commercially  viable  product,  there is no assurance that it would be able to
attain profitable operations.

YEAR 2000 READINESS DISCLOSURE

         The Year 2000  issue  refers to the  inability  of  computer  and other
information technology systems to properly process date and time information due
to the  programming  of a two digit year rather than a four digit year. The risk
is that a system  will  recognize  the digits  "00" as 1900 rather than the year
2000, or that the system may not  recognize  "00" as a year at all. As a result,
computers  and  embedded  processing  systems may be at risk of  malfunctioning,
particularly during the transition from 1999 to 2000.

         The Company has  completed  its  assessment  of the impact of Year 2000
issues on its business operations. The Year 2000 issue may affect the Company in
four principal areas including: (1) computer systems such as personal computers,
operating  systems,   business  software,  and  application  software  including
accounting systems,  technical support software and administration software; (2)
field assets (primarily embedded systems) such as programmable logic controllers
and equipment control panels; (3) other systems such as telephones, photocopiers
and facsimile machines; and (4) third-party suppliers and service providers such
as banks and insurance companies.

         To date, the Company has implemented  and tested its computer  software
and hardware for Year 2000  compliance  and has concluded  that its hardware and
software is Year 2000 compliant.

         The  Company's  Year 2000  program is designed to reduce the  Company's
risk of  material  losses  due to the  Year  2000  issue.  Management  does  not
anticipate any material  adverse effect from the Year 2000 issue;  however,  the
Company cannot be certain that it will not suffer  material  adverse  effects in
the event that third  parties upon which the Company is dependent  are unable to
resolve their Year 2000 issues.


ITEM 3.           DESCRIPTION OF PROPERTY.

         The  Company  does not own real  property.  The Company  shares  office
facilities in Vancouver,  British Columbia,  for its executive  offices,  and is
charged for office and rent and  administrative  services on a proportional cost
basis by an affiliate.  See Part I - Item 7. Certain  Relationships  and Related
Transactions.

         Praxis accesses its research  facilities through academic  appointments
of the directors with the Australian  National  University and the payment of an
overhead fee to the university for the use of the facilities.  These  facilities
include  laboratory  and  animal  facilities,  which are  already in use for the
purpose of  producing  carbohydrate-based  therapeutic  compounds  to be used in
pre-clinical  and  clinical  trials  and  meet  all  the  necessary   regulatory
requirements.  Praxis also has access to purpose  built and equipped  laboratory
facilities,  which  are  dedicated  to all  aspects  of  carbohydrate  chemistry
including synthesis, purification and analysis of compounds. The facilities also
allow the performance of most other aspects of chemistry that might be required.
Animal research  facilities for all  pre-clinical  studies are in place and meet
all  national  standards  for  care  and  use of  laboratory  animals.  Magnetic
resonance  imaging  and mass  spectroscopy  are  freely  accessible.  A  Silicon
Graphics   workstation  is  operated  and  owned  by  Praxis.  Full  information
technology  services are in place  enabling high speed  Internet  connection and
computerized  data  handling.  Other  John  Curtin  School of  Medical  Research
laboratories  and  scientists  are also  accessible  by  Praxis  in the event of
needing technology that is not directly available.


ITEM 4.           SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
                  MANAGEMENT.

         The following table provides certain information as to the officers and
directors  individually  and as a group,  and the holders of more than 5% of the
Company's common stock, as of December 10, 1999. Except as

                                        8
<PAGE>


otherwise  indicated,  the  persons  named in the  table  have sole  voting  and
investing power with respect to all shares of common stock owned by them.

<TABLE>
<CAPTION>

            NAME AND ADDRESS OF OWNER                NUMBER OF SHARES OWNED                PERCENT OF CLASS (1)<F1>
- -----------------------------------------------------------------------------------------------------------------------
<S>                                                         <C>                                     <C>
CEDE & Co.                                                  8,149,220 (2)<F2>                       68.93%
P.O. Box 222
Bowling Green Station
New York, NY 10274

Dr. Brett Charlton                                          1,666,110 (3)<F3>                       13.45%
24/1-9 Totterdell Street
Belconnen, 2617 Australia

                                                            1,566,110 (4)<F4>                       12.64%
Dr. William Cowden
56 Urambi Village
Darlington, NSW 2008
Australia

David Stadnyk                                               1,266,110 (4)<F4>                       10.22%
430 - 744 Hastings Street
Vancouver, BC V6C 1A5 Canada

Officers and directors as a group (3 persons)               4,498,330 (5)<F5>                       33.27%

- ------------
<FN>
<F1>
(1)      Where persons listed on this table have the right to obtain  additional
         shares of common stock through the exercise of  outstanding  options or
         warrants or the  conversion of  convertible  securities  within 60 days
         from  December  10,  1999,  these  additional  shares  are deemed to be
         outstanding for the purpose of computing the percentage of common stock
         owned by such  persons,  but are not deemed to be  outstanding  for the
         purpose  of  computing  the  percentage  owned  by  any  other  person.
         Percentages are based on 11,822,209 shares outstanding.

<F2>
(2)      CEDE & Co. holds the shares in nominee name on behalf of  broker-dealer
         firms.

<F3>
(3)      Includes 800,000 shares held in the name of Neysa Investment Ltd.

<F4>
(4)      Includes  566,110 shares  issuable upon exercise of stock options.  See
         Item 6. Executive Compensation.

<F5>
(5)      Includes 1,698,330 shares issuable upon exercise of stock options.  See
         Item 6. Executive Compensation.
</FN>
</TABLE>

CHANGES IN CONTROL

         We are not  aware of any  arrangements  that may  result in a change in
control of Praxis.


ITEM 5.           DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND CONTROL PERSONS.

         The officers and directors of the Company are as follows:


NAME                    AGE    POSITION
- ----                    ---    --------
Dr. Brett Charlton      43     President, Medical Director, and director

Dr. William B. Cowden   45     Vice President, Scientific Director, and director

David Stadnyk           35     Secretary and director

                                        9
<PAGE>

         The term of office of each director ends at the next annual  meeting of
Praxis' stockholders or when such director's successor is elected and qualifies.
The term of  office  of each  officer  ends at the next  annual  meeting  of the
Praxis' board of directors,  expected to take place  immediately  after the next
annual meeting of stockholders,  or when such officer's successor is elected and
qualifies.

         The last annual  meeting  was held on August 30,  1999,  in  Vancouver,
British Columbia.

         DR. BRETT CHARLTON,  President and a director of the Company since June
19, 1998, is also responsible for the institution and management of all clinical
trials as the medical  director of the Company.  He has basic clinical  training
and  clinical  involvement,  particularly  in  diabetes.  He has  held  academic
appointments at the Walter and Eliza Hall Institute and Stanford University, and
is now at the John  Curtin  School  of  Medical  Research,  Australian  National
University.  Dr.  Charlton is also  currently  Medical  Director of the Clinical
Studies Unit of the National  Health Sciences  Center.  Dr. Charlton spent three
years with Baxter  Healthcare,  as research manager,  where he was involved with
new technology assessment,  strategic planning and clinical trial management. He
has been consulting for the biomedical and  pharmaceutical  industry since 1984.
Dr.  Charlton  has  published  more than 50  scientific  papers in  medical  and
biomedical journals. He is a graduate of the University of New South Wales.

         DR.  WILLIAM B. COWDEN,  Vice  President  and a director of the Company
since  June 19,  1998,  is also chief  scientist  and  responsible  for all drug
development  programs and pre-clinical  testing. He is currently Senior Research
Fellow at the John Curtin School of Medical Research,  and Principal  Scientific
Advisor to ANUTech Pty Ltd.,  Canberra,  Australia.  Dr.  Cowden was  previously
Senior Scientist at Peptide Technology Ltd., an Australia based company. As part
of his work within the  commercial  sector Dr.  Cowden has been involved in drug
development   studies  from  the  earliest  stages  of  identification  of  drug
candidates,  including pre-clinical  assessment,  up to the early clinical trial
stage. Major  pharmaceutical  companies currently license some agents discovered
in his laboratory.  He has published over 100 papers in peer-reviewed scientific
medical journals.  He is the inventor and co-inventor on seven patents.  He is a
graduate of the University of Queensland.

         DAVID  STADNYK,  Secretary  and a director of the Company from June 19,
1998, to September 21, 1999, and since December 21, 1999, has diverse experience
in corporate  management and finance. He has served as the Chairman,  President,
Secretary  and a director of Goanna  Resources,  Inc., a publicly  listed mining
company (now known as Fairchild  International  Inc.) from its inception in June
1997  to  March  1999.  He  was  the   President  and  CEO  of  Alexander   News
International, a publicly traded newspaper publishing chain in Canada, from July
1994 to February  1997.  Mr.  Stadnyk was also a licensed  stockbroker  with two
national  investment  houses in  Canada.  Mr.  Stadnyk  is  currently  executive
director  of  Alexander  Cox & Co.  based in Sydney,  Australia  and  Vancouver,
British Columbia. He is a graduate of the University of British Columbia.

         No other  directorships are held by each director in any company with a
class of securities registered pursuant to Section 12 of the Securities Exchange
Act of 1934 or any  company  registered  as an  investment  company,  under  the
Investment Company Act of 1940.

         Drs.  Charlton  and  Cowden  and  Mr.  Stadnyk  may  be  deemed  to  be
"promoters" and "control persons" of the Company, as that term in defined in the
Securities Act of 1933.


ITEM 6.           EXECUTIVE COMPENSATION.

         The Company is not presently paying any executive  compensation  except
for consulting  fees to Dr. Cowden.  See Part I - Item 7. Certain  Relationships
and Related Transactions.  It has no long-term incentive plans. The Company does
not pay directors for their services as such nor does it pay any director's fees
for attendance at meetings.  Directors are reimbursed for any expenses  incurred
by them in their performance as directors.

         There are no employment  agreements with any of the Company's executive
officers.

                                       10
<PAGE>

STOCK OPTION PLAN

         On August 30, 1999,  the  Company's  shareholders  adopted a 1999 Stock
Option Plan under which a total of 1,698,330 shares were reserved  initially for
grant to provide  incentive  compensation  to officers  and key  employees.  The
number of shares available for grant adjusts  annually,  commencing on the first
day of the next  fiscal  year to a number  equal to 15% of the  number of shares
outstanding on last day of the fiscal year just completed.

         The board of directors  administers the Stock Option Plan.  Options may
be granted for up to 10 years at not less than the fair market value at the time
of grant,  except  that the term may not exceed five years and the price must be
110% of fair market value for any person who at the time of grant owns more than
10% of the total voting power of the Company.  Unless otherwise  specified in an
optionee's   agreement,   options   granted   under   the   plan  to   officers,
officer/directors,  and employees will become vested with the optionee after six
months.  The Plan will remain in effect until the board of directors  terminates
it,  except that no  incentive  stock  option,  as defined in Section 422 of the
Internal Revenue Code, may be granted after July 8, 2009.

         Options may be  exercised  by payment of the option  price (i) in cash,
(ii) by tender of shares of Company  common stock which have a fair market value
equal to the option price, or (iii) by such other  consideration as the board of
directors may approve at the time the option is granted.

         As of December 10, 1,698,330 options had been granted under the plan as
follows:
<TABLE>
<CAPTION>
           OPTIONEE                  Number of Options               Exercise Price                Expiration Date
<S>                                       <C>                             <C>                        <C>

Dr. Brett Charlton                        566,110                         $0.41                      12/09/2004

Dr. William Cowden                        566,110                         $0.41                      12/09/2004

David Stadnyk                             566,110                         $0.41                      12/09/2004
</TABLE>


ITEM 7.           CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

         Alexander Cox & Co., a company owned and  controlled by David  Stadnyk,
has advanced sums to the Company from time to time for working capital needs. At
May 31,  1999 and August 31,  1999,  $153,082  was owed to  Alexander  Cox & Co.
Interest  does not accrue and there is no date  established  for  repayment.  In
addition,  the Company shares office  facilities with Alexander Cox & Co. and is
charged for its proportional share of rent and administrative  services.  During
the year ended May 31, 1999, $14,874 was paid for rent and services.

         The Company entered into a Research,  Development and Licence Agreement
with Fairchild International Inc., an affiliate, dated as of May 11, 1999, which
closed  September  30,  1999.  Under  that  agreement,   Fairchild  obtained  an
exclusive,  worldwide  license to make,  use, and sell  products  and  processes
developed by Praxis relating to arthritis and dermal  wrinkles in  consideration
for 2,600,000 shares of Fairchild common stock and $250,000. A first installment
of $62,500 was paid on October 1, 1999.  Quarterly payments of $50,000 are to be
made beginning  January 1, 2000,  with a final payment of $37,500 due October 1,
2000. Praxis agreed to conduct certain research projects  commencing  October 1,
1999. Any new intellectual property developed as a result of that research is to
be included  as part of the  licensed  technology  and  licensed  to  Fairchild.
Fairchild is  authorized  to grant  sublicenses  and/or assign the license to an
affiliate.  Praxis is to be paid 35% of any consideration  received by Fairchild
from the sale of a licensed  product or the granting of a  sublicense,  less the
$250,000 and any other  development  costs,  manufacturing and production costs,
and marketing and selling costs.  David Stadnyk,  an officer and director of the
Company, is the holder of more than 10% of the outstanding shares of Fairchild.

         During the year ended May 31, 1999 and three  months  ended  August 31,
1999,  $4,643 and $25,472,  respectively,  were paid to Dr.  William  Cowden for
consulting fees.

                                       11
<PAGE>

ITEM 8.           DESCRIPTION OF SECURITIES.

GENERAL

         The Company is authorized to issue of up to 50,000,000 shares of common
stock,  $.001 par value per share,  and  10,000,000  shares of preferred  stock,
$.001 par  value  per  share.  The  following  summary  does not  purport  to be
complete.  You may wish to refer to the Company's  articles of incorporation and
bylaws, copies of which are available for inspection. None of the holders of any
class or series of the Company's  capital stock has preemptive rights or a right
to cumulative voting. As of December 10, 1999, there were issued and outstanding
11,822,209 shares of common stock and no shares of preferred stock.

PREFERRED STOCK

         The  Company's  board of  directors  may  determine  the  designations,
rights, preferences or other variations of each class or series of the preferred
stock. No classes or series of preferred  stock have been  established as of the
date of this registration statement.

COMMON STOCK

         As of December 10, 1999,  there were 11,822,209  shares of common stock
issued and outstanding.  The board of directors may issue  additional  shares of
common stock without the consent of the common stockholders.

         VOTING RIGHTS.  Each  outstanding  share of common stock is entitled to
one vote. The common  stockholders do not have cumulative  voting rights,  which
means that the holders of more than 50% of such  outstanding  shares  voting for
the election of directors can elect all of the directors to be elected,  if they
so choose.

         NO PREEMPTIVE  RIGHTS.  Holders of common stock are not entitled to any
preemptive rights.

         DIVIDENDS  AND  DISTRIBUTIONS.  Holders of common stock are entitled to
receive such  dividends as may be declared by the directors out of funds legally
available for dividends and to share pro rata in any distributions to holders of
common stock upon liquidation or otherwise.  However, the Company has never paid
cash dividends on its common stock, and does not expect to pay such dividends in
the foreseeable future.


                                     PART II

ITEM 1.           MARKET PRICE OF AND  DIVIDENDS ON THE  REGISTRANT'S  COMMON
                  EQUITY AND RELATED STOCKHOLDER MATTERS.

         Praxis  common  stock has been traded  over-the-counter  since July 23,
1998 on the OTC Bulletin Board under the symbol "PRXX". The following table sets
forth the range of high and low bid quotations for each fiscal quarter since the
stock began trading. These quotations reflect inter-dealer prices without retail
mark-up,  markdown,  or commissions  and may not  necessarily  represent  actual
transactions.

<TABLE>
<CAPTION>

                                                                                  BID PRICES
                                                                                  ----------

1999 FISCAL YEAR                                                       HIGH                           LOW
- ----------------                                                       ----                           ---

<S>                                                                    <C>                           <C>
Quarter ending 08/31/98                                                $3.25                         $0.75
Quarter ending 11/30/98                                                $0.88                         $0.06
Quarter ending 02/28/99                                                $0.54                         $0.06
Quarter ending 05/31/99                                                $1.70                         $0.19

2000 FISCAL YEAR
- ----------------

Quarter ending 08/31/99                                                $1.84                         $0.39
Quarter ending 11/30/99                                                $1.10                         $0.38
</TABLE>


                                       12
<PAGE>

         On December 10, 1999, the closing price for the common stock was $0.41.
The number of record  holders of the common stock as of December  10, 1999,  was
306 according to the Company's transfer agent. Holders of shares of common stock
are entitled to dividends  when, and if,  declared by the board of directors out
of funds legally available therefor.


ITEM 2.           LEGAL PROCEEDINGS.

         None.


ITEM 3.           CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS.

         None.


ITEM 4.           RECENT SALES OF UNREGISTERED SECURITIES.

         During the past three years,  the Company has sold shares of its Common
Stock,  which were not registered  under the Securities Act of 1933, as amended,
as follows:

         1.       In July 1998, the Company  acquired  Praxis-Nevada  by issuing
                  5,000,000  shares of common  stock to the 13  shareholders  of
                  Praxis-Nevada in reliance upon the exemption from registration
                  contained in Rule 504 of  Regulation D. No  underwriters  were
                  used and no underwriting commissions were paid.

         2.       In July 1998,  the  Company  issued  305,403  shares of Common
                  Stock to 3  persons  for  services  valued  at  $30,540.30  in
                  reliance upon the  exemption  from  registration  contained in
                  Rule 504 under the  Securities  Act of 1933.  No  underwriters
                  were used and no underwriting commissions were paid.

         3.       In July 1998,  the  Company  issued  215,450  shares of Common
                  Stock to 142 persons for cash of $107,725 in reliance upon the
                  exemption  from  registration  contained in Rule 504 under the
                  Securities  Act of  1933.  No  underwriters  were  used and no
                  underwriting commissions were paid.

         4.       In August 1998,  the Company sold a  convertible  debenture to
                  Sholem  Liebenthal  in the  principal  amount of $100,000  due
                  August  26,  1999  in  reliance   upon  the   exemption   from
                  registration  contained in Section 4(2) of the  Securities Act
                  of 1933. From September 1998 to February 1999, Mr.  Liebenthal
                  converted  $50,000 into 617,989  shares of Common  Stock.  The
                  remaining  principal  of $50,000 was  redeemed  for cash.  The
                  Company  relied upon Rule 504 for the  issuance of the shares.
                  No underwriters were used and no underwriting commissions were
                  paid.

         5.       In September 1998, the Company issued 516,832 shares of Common
                  Stock to 6 persons for services valued at $129,208 in reliance
                  upon the  exemption  from  registration  contained in Rule 504
                  under the  Securities Act of 1933. No  underwriters  were used
                  and no underwriting commissions were paid.

         6.       In December  1998,  the Company sold 600,000  shares of Common
                  Stock  to  Grant  Douglas  Publishing,  Inc.  for  $30,000  in
                  reliance upon the  exemption  from  registration  contained in
                  Rule

                                       13
<PAGE>

                  504 under the  Securities  Act of 1933. No  underwriters  were
                  used and no  underwriting  commissions  were paid.  Through an
                  oversight the shares were not issued until June 1999.

         7.       In February  1999,  the  Company  issued  2,583,000  shares of
                  Common Stock for  services  valued at $120,000 to 7 persons in
                  reliance upon the  exemption  from  registration  contained in
                  Rule 504 under the  Securities  Act of 1933.  No  underwriters
                  were used and no underwriting commissions were paid.

         8.       In February  1999, the Company issued 300,000 shares of Common
                  Stock to Anutech as consideration for the Company's license in
                  reliance upon the  exemption  from  registration  contained in
                  Section 4(2) of the  Securities  Act of 1933. No  underwriters
                  were used and no underwriting commissions were paid.

         9.       In February  1999,  the Company sold 250,000  shares of Common
                  Stock for cash of $50,000 to Jewett  Finance Corp. in reliance
                  upon the  exemption  from  registration  contained in Rule 504
                  under the  Securities Act of 1933. No  underwriters  were used
                  and no underwriting commissions were paid.

         10.      In March 1999, the Company sold 833,333 shares of Common Stock
                  for cash of  $100,000  to Annette  Gross-Blotekamp  and Jewett
                  Finance Corp. in reliance upon the exemption from registration
                  contained  in  Rule  504 of the  Securities  Act of  1933.  No
                  underwriters  were used and no underwriting  commissions  were
                  paid.

         11.      In September  1999,  the Company sold 500,000 shares of Common
                  Stock for cash of $150,000 to Jeffrey  Stone in reliance  upon
                  the exemption from  registration  contained in Rule 504 of the
                  Securities  Act of  1933.  No  underwriters  were  used and no
                  underwriting commissions were paid.


ITEM 5.           INDEMNIFICATION OF DIRECTORS AND OFFICERS.

         Section  16-10a-901  ET SEQ. of the Utah Business  Corporation  Act and
Article VIII of the Company's  Articles of  Incorporation  permit the Company to
indemnify its officers and directors and certain other persons against  expenses
in defense of a suit to which they are parties by reason of such office, so long
as the persons  conducted  themselves  in good faith and the persons  reasonably
believed that their conduct was in the Company's  best  interests or not opposed
to the  Company's  best  interests,  and with respect to any criminal  action or
proceeding,  had no  reasonable  cause to believe  their  conduct was  unlawful.
Indemnification  is not permitted in  connection  with a proceeding by or in the
right of the corporation in which the officer or director was adjudged liable to
the  corporation or in connection  with any other  proceeding  charging that the
officer  or  director  derived  an  improper  personal  benefit,  whether or not
involving action in an official capacity.


                                    PART F/S

See pages beginning with page F-1.


                                       14
<PAGE>

                                    PART III


<TABLE>
<CAPTION>

    REGULATION                                                                                          SEQUENTIAL
    S-B NUMBER                                                                                         PAGE NUMBER
                                                       EXHIBIT
       <S>         <C>                                                                                     <C>
       2.1         Stock Exchange Agreement with Micronetics, Inc.                                         ___
       3.1         Articles of Incorporation, as amended and restated                                      ___
       3.2         Bylaws                                                                                  ___
       10.1        Research, Development and Licence Agreement dated May 11, 1999 between                  ___
                   Praxis Pharmaceuticals, Inc. and Fairchild International Inc.
       10.2        Exclusive Licence Agreement dated October 14, 1999 between Anutech Pty                  ___
                   Ltd. and Praxis Pharmaceuticals Australia Pty Ltd.
       10.3        Licence Agreement dated October 14, 1999 between Anutech Pty Ltd. and                   ___
                   Praxis Pharmaceuticals Inc.
       10.4        Shareholders Agreement dated as of October 15, 1999, between Praxis                     ___
                   Pharmaceuticals Australia Pty Ltd., Praxis Pharmaceuticals Inc., Perpetual
                   Trustees Nominees Limited, and Rothschild Bioscience Managers Limited
       10.5        1999 Stock Option Plan                                                                  ___
        21         Subsidiaries of the registrant                                                          ___
        27         Financial Data Schedule                                                                 ___
</TABLE>







                                       15
<PAGE>




                                   SIGNATURES

         In accordance  with Section 12 of the Securities  Exchange Act of 1934,
the registrant caused this registration  statement to be signed on its behalf by
the undersigned, thereunto duly authorized.

                                      PRAXIS PHARMACEUTICALS, INC.



Date: December 20, 1999               By: /S/ DR. BRETT CHARLTON
                                         ----------------------------
                                              Dr. Brett Charlton, President




                                       16

<PAGE>

                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                              FINANCIAL STATEMENTS

                                 AUGUST 31, 1999

                           (EXPRESSED IN U.S. DOLLARS)





                        UNAUDITED - SEE NOTICE TO READER


<PAGE>


                           STEELE & CO.*
                   CHARTERED ACCOUNTANTS
*Representing incorporated professionals
                               SUITE 808      TELEPHONE:   (604) 687-8808
                808 WEST HASTINGS STREET      TELEFAX:     (604) 687-2702
         VANCOUVER, B.C., CANADA V6C 1C8      EMAIL:       [email protected]





                                NOTICE TO READER








WE HAVE COMPILED THE BALANCE SHEET OF PRAXIS PHARMACEUTICALS INC. (A DEVELOPMENT
STAGE  COMPANY)  AS AT AUGUST 31,  1999 AND THE  STATEMENTS  OF  OPERATIONS  AND
DEFICIT AND CASH FLOW FOR THE THREE MONTH PERIODS ENDED AUGUST 31, 1999 AND 1998
FROM  INFORMATION  PROVIDED  BY  MANAGEMENT.  WE HAVE NOT  AUDITED,  REVIEWED OR
OTHERWISE  ATTEMPTED TO VERIFY THE ACCURACY OR COMPLETENESS OF SUCH  INFORMATION
AND,  ACCORDINGLY,  WE DO NOT EXPRESS AN OPINION ON THEM.  READERS ARE CAUTIONED
THAT THESE STATEMENTS MAY NOT BE APPROPRIATE FOR THEIR PURPOSES.









VANCOUVER, CANADA                                            /s/STEELE & CO.
NOVEMBER 15, 1999                                          CHARTERED ACCOUNTANTS


<PAGE>










                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                                  BALANCE SHEET

                                 AUGUST 31, 1999

                           (EXPRESSED IN U.S. DOLLARS)




                                                                     1999
                                                                     ----
ASSETS
  CURRENT
    CASH                                                             $   36,945
                                                                     ==========
LIABILITIES

  CURRENT
    ACCOUNTS PAYABLE                                                 $   32,915
    OWING TO RELATED PARTIES                                            153,082
                                                                     ----------

                                                                        185,997
                                                                     ----------

STOCKHOLDERS' EQUITY

  SHARE CAPITAL
    AUTHORIZED
    50,000,000 COMMON SHARES WITH A PAR VALUE
               OF $0.001 PER SHARE
    10,000,000 PREFERRED SHARES WITHOUT PAR VALUE
    ISSUED AND PAID IN CAPITAL (NOTE 2)
    11,322,209 COMMON SHARES                                            667,473

  DEFICIT ACCUMULATED DURING THE
   DEVELOPMENT STAGE                                                   (816,525)
                                                                     ----------

  TOTAL STOCKHOLDERS' EQUITY (DEFICIENCY)                              (149,052)
                                                                     ----------

TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                           $   36,945
                                                                     ==========


APPROVED BY THE DIRECTORS

_________________________

_________________________




                        UNAUDITED - SEE NOTICE TO READER


<PAGE>








<TABLE>


                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                      STATEMENTS OF OPERATIONS AND DEFICIT

               FOR THE THREE MONTHS ENDED AUGUST 31, 1999 AND 1998

                           (EXPRESSED IN U.S. DOLLARS)


<CAPTION>


                                                                                     1999             1998
                                                                                     ----             ----
<S>                                                                            <C>                 <C>

OPERATING EXPENSES
  BANK CHARGES AND EXCHANGE                                                    $       1,967       $      1,093
  CONSULTING                                                                          10,414                  -
  RESEARCH AND DEVELOPMENT                                                            22,352             16,559
    RECOVERED COSTS                                                                  (19,965)                 -
  OFFICE AND SECRETARIAL                                                               2,786              1,428
  PROMOTION AND TRAVEL                                                                28,643              8,716
  PROFESSIONAL FEES                                                                   10,042              9,363
  RELATED PARTY ADMINISTRATION CHARGES                                                33,316              1,628
  RENT                                                                                     -                766
  SHAREHOLDER INFORMATION                                                                931                  -
  TRANSFER AGENT AND FILING FEES                                                       2,169              1,279
                                                                               -------------       ------------

NET LOSS FOR THE PERIOD                                                               92,655             40,832

DEFICIT BEGINNING OF THE PERIOD                                                      723,870            193,296
                                                                               -------------       ------------

DEFICIT END OF THE PERIOD                                                      $     816,525       $    234,128
                                                                               =============       ============

BASIC LOSS PER SHARE                                                           $        0.01       $       0.02
                                                                               =============       ============
</TABLE>




                        UNAUDITED - SEE NOTICE TO READER


<PAGE>

<TABLE>

                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                             STATEMENTS OF CASH FLOW

               FOR THE THREE MONTHS ENDED AUGUST 31, 1999 AND 1998

                           (EXPRESSED IN U.S. DOLLARS)


<CAPTION>


                                                                                    1999              1998
                                                                                    ----              ----
<S>                                                                            <C>                 <C>

CASH PROVIDED (USED) BY
  OPERATING ACTIVITIES
    NET LOSS FOR THE PERIOD                                                    $     (92,655)      $    (40,832)
    CHANGE IN NON-CASH OPERATING ITEM
      ACCOUNTS PAYABLE                                                                26,087              8,203
                                                                               -------------       ------------
                                                                                     (66,568)           (32,629)
                                                                               --------------      -------------
  FINANCING ACTIVITIES
    OWING TO RELATED PARTIES                                                               -            (23,652)
    SHARE CAPITAL ISSUED FOR CASH                                                     30,000            112,725
    SHARE SUBSCRIPTIONS                                                              (30,000)           (70,000)
                                                                               -------------       ------------
                                                                                           -             19,073
                                                                               -------------       ------------
CHANGE IN CASH FOR THE PERIOD                                                        (66,568)           (13,556)
CASH BEGINNING OF THE PERIOD                                                         103,513             23,255
                                                                               -------------       ------------
CASH END OF THE PERIOD                                                         $      36,945       $      9,699
                                                                               =============       ============
</TABLE>








                        UNAUDITED - SEE NOTICE TO READER


<PAGE>


                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                        NOTES TO THE FINANCIAL STATEMENTS

                                 AUGUST 31, 1999



1.      ACCOUNTING POLICES AND NOTES

        The accounting policies followed by the company are unchanged from those
        outlined in the audited financial  statements for the year ended May 31,
        1999.   The  notes  to  the   financial   statements  at  May  31,  1999
        substantially  apply to the interim  financial  statements at August 31,
        1999 and are not repeated here. All adjustments have been made which, in
        the  opinion  of  management,  are  necessary  in  order  to make  these
        financial statements not misleading.

2.      SHARE CAPITAL

<TABLE>
        A.     ISSUED AND PAID IN CAPITAL
<CAPTION>

                                                                                    SHARES       CONSIDERATION
<S>                                                                            <C>              <C>
               Common shares
               Balance at May 31, 1999                                            10,722,209    $       637,473

               Issued during the period
                     For cash
                      @ $0.05 per share                                              600,000             30,000
                                                                               -------------    ---------------

               Balance at August 31, 1999                                         11,322,209    $       667,473
                                                                               =============    ===============
</TABLE>

        B.     SUBSEQUENT EVENTS

               Stock options to acquire 250,000 common shares at $0.20 per share
               and 250,000  common shares at $0.40 per shares for total proceeds
               of $150,000 were exercised and the shares were issued  subsequent
               to the end of the period.

               A share consolidation of one new share for five old common shares
               was  authorized  by the  shareholders  and to be  declared by the
               directors on or before August 23, 2000.

3.      PHARMACEUTICAL RESEARCH AND DEVELOPMENT AGREEMENTS

        The Company has entered into a research and  development  agreement with
        an Australian  corporate  third party subject to common  management.  In
        exchange for the funding of research and  development of  pharmaceutical
        products,  the  Company  acquires  the right of first  refusal to obtain
        exclusive  licences to the  products.  The  Company has entered  into an
        agreement,   effective   September  30,  1999,  to  grant  a  world-wide
        sub-licence  for  certain  products  to a public  company  under  common
        management.  In exchange for the sub-licence,  the Company is to receive
        common shares, representing a 24% ownership interest at the closing date
        of the agreement.  The third party will also pay the Company $250,000 to
        reimburse the Company for research and development costs incurred.
                        UNAUDITED - SEE NOTICE TO READER


<PAGE>



                           PRAXIS PHARMACEUTICALS INC.
                          (A DEVELOPMENT STAGE COMPANY)

                        NOTES TO THE FINANCIAL STATEMENTS

                                 AUGUST 31, 1999



4.      SEGMENTED INFORMATION

        a.     Cash

               The Company  maintains  its cash  balance in U.S.,  Canadian  and
               Australian  currencies.  At  the  period  end,  the  U.S.  dollar
               equivalents were as follows.


               U.S. dollars                                    $       6,336
               Australian dollars                                     30,248
               Canadian dollars                                          361
                                                               -------------
                                                               $      36,945
                                                               =============

<TABLE>
        b.     Geographic Segments

<CAPTION>
                                                            DOMESTIC             FOREIGN              TOTAL
                                                            --------             -------              -----
<S>                                                        <C>                 <C>                 <C>
               Net loss for the period                     $   54,303          $   38,352          $   92,655
                                                           ==========          ==========          ==========
               Assets - current                            $    6,336          $   30,609          $   36,945
                                                           ==========          ==========          ==========
</TABLE>


               The Company's  activities are all in the one industry  segment of
               the research and development of pharmaceutical products.





                        UNAUDITED - SEE NOTICE TO READER



<PAGE>

                           PRAXIS PHARMACEUTICALS INC.
                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                        CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999


                           (EXPRESSED IN U.S. DOLLARS)








<PAGE>


                           STEELE & CO.*
                   CHARTERED ACCOUNTANTS
*Representing incorporated professionals
                               SUITE 808      TELEPHONE:   (604) 687-8808
                808 WEST HASTINGS STREET      TELEFAX:     (604) 687-2702
         VANCOUVER, B.C., CANADA V6C 1C8      EMAIL:       [email protected]

                          INDEPENDENT AUDITORS' REPORT


TO THE SHAREHOLDERS OF
PRAXIS PHARMACEUTICALS INC.
 (FORMERLY MICRONETICS, INC.)


WE  HAVE  AUDITED  THE  ACCOMPANYING   CONSOLIDATED  BALANCE  SHEETS  OF  PRAXIS
PHARMACEUTICALS INC. (FORMERLY MICRONETICS,  INC.) (A DEVELOPMENT STAGE COMPANY)
AS OF MAY  31,  1999  AND  1998  AND  THE  RELATED  CONSOLIDATED  STATEMENTS  OF
OPERATIONS AND DEFICIT,  CHANGES IN  STOCKHOLDERS'  EQUITY AND CASH FLOW FOR THE
PERIODS THEN ENDED AND CUMULATIVE TO MAY 31, 1999.  THESE  FINANCIAL  STATEMENTS
ARE THE  RESPONSIBILITY OF THE COMPANY'S  MANAGEMENT.  OUR  RESPONSIBILITY IS TO
EXPRESS AN OPINION ON THESE FINANCIAL STATEMENTS BASED ON OUR AUDIT.

WE CONDUCTED OUR AUDIT IN ACCORDANCE WITH GENERALLY ACCEPTED AUDITING STANDARDS.
THOSE STANDARDS  REQUIRE THAT WE PLAN AND PERFORM THE AUDIT TO OBTAIN REASONABLE
ASSURANCE   ABOUT  WHETHER  THE  FINANCIAL   STATEMENTS  ARE  FREE  OF  MATERIAL
MISSTATEMENT.  AN AUDIT INCLUDES EXAMINING, ON A TEST BASIS, EVIDENCE SUPPORTING
THE AMOUNTS AND DISCLOSURES IN THE FINANCIAL STATEMENTS.  AN AUDIT ALSO INCLUDES
ASSESSING THE  ACCOUNTING  PRINCIPLES  USED AND  SIGNIFICANT  ESTIMATES  MADE BY
MANAGEMENT,  AS WELL AS EVALUATING THE OVERALL FINANCIAL STATEMENT PRESENTATION.
WE BELIEVE THAT OUR AUDIT PROVIDES A REASONABLE BASIS FOR OUR OPINION.

IN OUR OPINION, THE CONSOLIDATED  FINANCIAL STATEMENTS REFERRED TO ABOVE PRESENT
FAIRLY,   IN  ALL  MATERIAL   RESPECTS,   THE   FINANCIAL   POSITION  OF  PRAXIS
PHARMACEUTICALS  INC. (FORMERLY  MICRONETICS,  INC.) AS AT MAY 31, 1999 AND 1998
AND THE RESULTS OF ITS  OPERATIONS  AND ITS CASH FLOW FOR THE PERIODS THEN ENDED
IN CONFORMITY WITH GENERALLY ACCEPTED ACCOUNTING PRINCIPLES.

THE ACCOMPANYING  CONSOLIDATED  FINANCIAL STATEMENTS HAVE BEEN PREPARED ASSUMING
THAT THE COMPANY WILL CONTINUE AS A GOING CONCERN. AS DISCUSSED IN NOTE 3 TO THE
FINANCIAL STATEMENTS, THE COMPANY HAS SUFFERED LOSSES FROM OPERATIONS, HAS A NET
CAPITAL DEFICIENCY AND THERE IS NO REVENUE STREAM FROM OPERATIONS.  AS A RESULT,
THERE IS  UNCERTAINTY  ABOUT ITS  ABILITY TO CONTINUE  AS A GOING  CONCERN.  THE
FINANCIAL  STATEMENTS DO NOT INCLUDE ANY ADJUSTMENTS  THAT MIGHT RESULT FROM THE
OUTCOME OF THIS UNCERTAINTY.




VANCOUVER, CANADASTEELE & CO.                                    /s/STEELE & CO.
OCTOBER 8, 1999                                            CHARTERED ACCOUNTANTS


<PAGE>

<TABLE>

                           PRAXIS PHARMACEUTICALS INC.
                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                           CONSOLIDATED BALANCE SHEETS

                              MAY 31, 1999 AND 1998
                           (EXPRESSED IN U.S. DOLLARS)


<CAPTION>

                                                                                     1999                1998
                                                                                     ----                ----
<S>                                                                            <C>                 <C>
ASSETS
 CURRENT
  CASH (NOTE 8)                                                                $        103,513    $        23,255
                                                                               ================    ===============
LIABILITIES
 CURRENT

  ACCOUNTS PAYABLE                                                             $          6,828    $             -
  REORGANIZATION COSTS PAYABLE                                                                -            100,000
  OWING TO RELATED PARTIES (NOTE 4)                                                     153,082             42,551
                                                                               ----------------    ---------------
                                                                                        159,910            142,551
                                                                               ----------------    ---------------
 COMMITMENTS (NOTE 7)

STOCKHOLDERS' EQUITY (DEFICIENCY)

 SHARE CAPITAL (NOTE 5)

  AUTHORIZED
   50,000,000 COMMON SHARES WITH A PAR VALUE
              OF $0.001 PER SHARE

  ISSUED AND PAID IN CAPITAL                                                            637,473                  -
   10,722,209 COMMON SHARES

 SHARE SUBSCRIPTIONS (NOTE 5)                                                            30,000             74,000

 DEFICIT ACCUMULATED DURING                                                            (723,870)          (193,296)
  THE DEVELOPMENT STAGE                                                        -----------------   ----------------

TOTAL STOCKHOLDER'S EQUITY (DEFICIENCY)                                                 (56,397)          (119,296)
                                                                               -----------------   ----------------
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                                     $        103,513    $        23,255
                                                                               ================    ===============
</TABLE>

APPROVED BY THE DIRECTORS

- ---------------------------------

- ---------------------------------

              THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THESE
                       CONSOLIDATED FINANCIAL STATEMENTS



<PAGE>

<TABLE>

                           PRAXIS PHARMACEUTICALS INC.
                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                CONSOLIDATED STATEMENTS OF OPERATIONS AND DEFICIT

                         FOR THE YEAR ENDED MAY 31, 1999
            AND THE PERIOD FROM JUNE 20, 1997 (DATE OF INCORPORATION)
                                 TO MAY 31, 1998

                           (EXPRESSED IN U.S. DOLLARS)

<CAPTION>


                                                               CUMULATIVE
                                                                   TO                      PERIOD ENDED
                                                                 MAY 31                       MAY 31
                                                                  1999               1999                1998
                                                                  ----       -----------------------------------------
<S>                                                        <C>                  <C>                 <C>

PROJECT COSTS
 RESEARCH AGREEMENT AMENDMENT                              $         45,000    $         45,000    $             -
 RESEARCH                                                           142,472              92,456             50,016
 PATENT COSTS                                                         2,820                   -              2,820
                                                           ----------------    ----------------    ---------------
                                                                    190,292             137,456             52,836
                                                           ----------------    ----------------    ---------------
ADMINISTRATION EXPENSES

 RELATED PARTY ADMINISTRATION                                        18,493              14,874              3,619
  CHARGES
 BANK CHARGES AND FOREIGN                                             2,450               2,450                  -
  EXCHANGE
 CONSULTING                                                         253,358             253,358                  -
 FILING FEES                                                          1,484               1,484                  -
 FINDERS FEES                                                         7,500               7,500                  -
 OFFICE, RENT AND SECRETARIAL                                        11,200               7,508              3,692
 PROFESSIONAL FEES                                                   32,486              24,337              8,149
 TRANSFER AGENT FEES                                                  2,013               2,013                  -
 TRAVEL AND ENTERTAINMENT                                            79,594              79,594                  -
                                                           ----------------    ----------------    ---------------
                                                                    408,578             393,118             15,460
                                                           ----------------    ----------------    ---------------
NET LOSS FOR THE PERIOD (NOTE 6)                           $        598,870             530,574             68,296
                                                           ================
DEFICIT BEGINNING OF THE PERIOD                                                         193,296                  -
REORGANIZATION COSTS (NOTE 2)                                                                 -            125,000
                                                           ----------------    ----------------    ---------------
DEFICIT END OF THE PERIOD                                                      $        723,870    $       193,296
                                                                               ================    ===============
BASIC LOSS PER SHARE                                                           $           0.07
                                                                               ================
</TABLE>

              THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THESE
                       CONSOLIDATED FINANCIAL STATEMENTS


<PAGE>



<TABLE>

                           PRAXIS PHARMACEUTICALS INC.
                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

           CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY

                         FOR THE YEAR ENDED MAY 31, 1999
            AND THE PERIOD FROM JUNE 20, 1997 (DATE OF INCORPORATION)
                                 TO MAY 31, 1998

                           (EXPRESSED IN U.S. DOLLARS)


<CAPTION>
                                                                                                                      TOTAL
                                        COMMON SHARES             CAPITAL IN        SHARE                            STOCK-
                                        -------------             EXCESS OF       SUBSCRIP-                          HOLDERS'
                                    SHARES        AMOUNT          PAR VALUE         TIONS          DEFICIT           EQUITY
                                    ------        ------          ---------         -----          -------           ------
<S>                             <C>         <C>                 <C>             <C>              <C>               <C>

Share subscriptions                      -  $          -        $           -   $       74,000   $            -    $      74,000
Net loss for the period                  -             -                    -                -          (68,296)         (68,296)
Re-organization costs                    -             -                    -                -         (125,000)        (125,000)
                                ----------  ------------        -------------   --------------   --------------    --------------
Stockholders' equity
(deficiency) at May 31, 1998             -             -                    -           74,000         (193,296)        (119,296)

Common shares
  Issued for cash
    @ $0.001 per share           5,000,000         5,000                    -           (5,000)               -                -
    @ $0.12 per share              833,333           833               99,167                -                -          100,000
    @ $0.20 per share              250,000           250               49,750                -                -           50,000
    @ $0.50 per share              215,450           215              107,510          (69,000)               -           38,725
  Issued for services
    @ $0.03 per share            1,400,000         1,400               40,600                -                -           42,000
    @ $0.05 per share              800,000           800               39,200                -                -           40,000
    @ $0.10 per share              383,000           383               37,617                -                -           38,000
    @ $0.25 per share              516,832           517              128,691                -                -          129,208
  Issued for conversion of
   debentures
    @ $0.03 per share              325,926           326               10,674                -                -           11,000
    @ $0.11 per share              124,444           124               13,876                -                -           14,000
    @ $0.14 per share              106,667           107               14,893                -                -           15,000
    @ $0.16 per share               60,952            61                9,939                -                -           10,000
  Issued for reorganization
   costs @ $0.10 per share         305,403           305               30,235                -                -           30,540
  Issued for research
   agreement amendment             300,000           300               44,700                -                -           45,000
  Acquired on reorganization
   acquisition                     100,202           100                 (100)               -                -                -
Share subscriptions                      -             -                    -           30,000                -           30,000
Net loss for the year                    -             -                    -                -         (530,574)        (530,574)
                                ----------  ------------        -------------   --------------   ---------------   --------------
Stockholders' equity
(deficiency) at May 31, 1999    10,722,209  $     10,721        $     626,752   $       30,000   $     (723,870)   $     (56,397)
                                ==========  ============        =============   ==============   ==============    ==============
</TABLE>



              THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THESE
                       CONSOLIDATED FINANCIAL STATEMENTS


<PAGE>


<TABLE>
                                            PRAXIS PHARMACEUTICALS INC.
                                           (FORMERLY MICRONETICS, INC.)
                                           (A DEVELOPMENT STAGE COMPANY)

                                       CONSOLIDATED STATEMENTS OF CASH FLOW

                                          FOR THE YEAR ENDED MAY 31, 1999
                             AND THE PERIOD FROM JUNE 20, 1997 (DATE OF INCORPORATION)
                                                  TO MAY 31, 1998

                                            (EXPRESSED IN U.S. DOLLARS)

<CAPTION>

                                                               CUMULATIVE
                                                                   TO                     PERIODS ENDED
                                                                 MAY 31                       MAY 31
                                                                  1999               1999                1998
                                                                  ----        ----------------------------------------
<S>                                                        <C>                  <C>                 <C>

CASH PROVIDED (USED) BY
 OPERATING ACTIVITIES
  NET LOSS FOR THE PERIOD                                  $         (598,870)  $        (530,574)  $        (68,296)
  ITEMS NOT AFFECTING CASH FLOW
  SHARE CAPITAL ISSUED
   FOR CONSULTING                                                     249,208             249,208                  -
   FOR RESEARCH AGREEMENT
    AMENDMENTS                                                         45,000              45,000                  -
  CHANGE IN NON-CASH  OPERATING ITEMS
   ACCOUNTS PAYABLE                                                     6,828               6,828                  -
                                                           ------------------  ------------------  -----------------
                                                                     (297,834)           (229,538)           (68,296)
                                                           ------------------  ------------------  -----------------
FINANCING ACTIVITIES
 OWING TO RELATED PARTIES                                             153,082             110,531             42,551
 SHARE CAPITAL ISSUED
  FOR CASH                                                            262,725             262,725                  -
  FOR CONVERSION OF DEBENTURES                                         50,000              50,000                  -
 SHARE SUBSCRIPTIONS                                                   30,000             (44,000)            74,000
 REORGANIZATION COSTS                                                 (94,460)            (69,460)           (25,000)
                                                           ------------------  ------------------  -----------------
                                                                      401,347             309,796             91,551
                                                           ------------------  ------------------  -----------------
CHANGE IN CASH FOR THE PERIOD                                         103,513              80,258             23,255
CASH BEGINNING OF THE PERIOD                                                -              23,255                  -
                                                           ------------------  ------------------  -----------------
CASH END OF THE PERIOD                                     $          103,513    $        103,513    $        23,255
                                                           ==================  ==================  =================
</TABLE>


              THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THESE
                       CONSOLIDATED FINANCIAL STATEMENTS


<PAGE>




                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




1.  ACCOUNTING POLICIES

    a.  Basis of Presentation

        These  consolidated  financial  statements  include the  accounts of the
        Company and its wholly-owned  subsidiaries,  Praxis Pharmaceuticals Inc.
        (a  Nevada  corporation)  and  Praxis  Pharmaceuticals   Australia  Pty.
        Limited.  These  financial  statements  have been prepared in accordance
        with  accounting  principles  and  practices  generally  accepted in the
        United States.

    b.  Pharmaceutical Research and Development

        The Company is engaged in the research and development of pharmaceutical
        products and expenses all costs incurred as period costs. The underlying
        value of the  pharmaceutical  products  is entirely  dependent  upon the
        development of marketable products, the ability of the Company to obtain
        the  necessary  financing  to  complete   development  and  upon  future
        profitable production.

    c.  Use of Estimates

        The  preparation  of financial  statements in conformity  with generally
        accepted accounting principles requires management to make estimates and
        assumptions that affect the amounts reported in the financial statements
        and  accompanying  disclosures.  Although  these  estimates are based on
        management's  best  knowledge of current  events and actions the Company
        may  undertake  in the  future,  actual  results  may  differ  from  the
        estimates.

    d.  Foreign Currency

        Transactions in foreign currencies are translated at rates prevailing on
        the  dates  of  the   transactions.   Monetary  assets  and  liabilities
        denominated in foreign currencies have been translated into U.S. dollars
        at a rate of exchange  prevailing at year end. Exchange gains and losses
        from foreign  currency  translation  adjustments are included in current
        costs.

<PAGE>


                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




1.  ACCOUNTING POLICIES (CONTINUED)

    e.  Income Taxes

        The Company has incurred  operating  losses which are  available for tax
        credit carry forward. No certainty exists whether it is more likely than
        not that some  portion of these  amounts will be realized by a reduction
        of future taxes payable and no deferred tax asset has been recognized.

    f.  Uncertainty Due to Year 2000 Issue

        The Year  2000  Issue  arises  because  many  computerized  systems  may
        recognize  the year 2000 as some other  date,  resulting  in errors when
        information using year 2000 dates is processed.  The effects of the Year
        2000 Issue may be experienced  before, on or after January 1, 2000, and,
        if not addressed,  the impact on operations and financial  reporting may
        range from minor  errors to  significant  systems  failure  which  could
        affect an entity's ability to conduct normal business operations.  It is
        not  possible  to be  certain  that all  aspects  of the Year 2000 Issue
        affecting  the  Company,  including  those  related  to the  efforts  of
        customers, suppliers, or other third parties, will be fully resolved.

2.  CORPORATE RE-ORGANIZATION, NAME CHANGE AND ACQUISITION OF
     PRAXIS PHARMACEUTICALS INC. (A NEVADA CORPORATION)

    The  re-organization  of  the  Company  included  the  consolidation  of the
    Company's  common shares to 100,202  outstanding  on the basis of 118.45 old
    shares for 1 new share,  cancellation  of 51,969  post-consolidation  common
    shares,  and the  change  of the  name  from  Micronetics,  Inc.  to  Praxis
    Pharmaceuticals Inc. (a Utah corporation).

    By a share  exchange  agreement,  the  Company  acquired a 100%  interest in
    Praxis  Pharmaceuticals  Inc.  (a Nevada  corporation),  a private  company.
    5,000,000 common shares were issued in exchange for all of the issued shares
    of the private company. In conjunction with the re-organization, the Company
    completed a private  placement of 215,450  common shares and issued  305,403
    common shares in partial  settlement of its commitment  for  re-organization
    costs.  The acquisition has been accounted for using the purchase method and
    applying accounting  principles  applicable to a reverse takeover.  As such,
    the Company is a continuation  of both the business and financial  reporting
    of the  private  company  and the  comparative  figures  presented  in these
    financial statements are for its year ended May 31, 1998.



<PAGE>


                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




3.  GOING CONCERN CONSIDERATIONS

    As at May 31, 1999, the Company had not reached a level of operations  which
    would finance day to day activities.  These  financial  statements have been
    prepared on the assumption  that the Company is a going concern,  meaning it
    will  continue in operation for the  foreseeable  future and will be able to
    realize  assets  and  discharge   liabilities  in  the  ordinary  course  of
    operations. Different basis of measurement may be appropriate when a Company
    is not  expected to continue  operations  for the  foreseeable  future.  The
    Company's  continuation  as a going concern is dependent upon its ability to
    attain  profitable  operations  and generate  funds  therefrom  and/or raise
    equity  capital  or  borrowings  from  third  parties  and  related  parties
    sufficient  to meet  current and future  obligations.  The Company  suffered
    losses from operations of $530,574 and $68,296 for the periods ended May 31,
    1999 and 1998 and had net capital  deficiencies  of $56,397 and  $119,296 at
    May 31, 1999 and 1998 respectively.

4.  OWING TO RELATED PARTIES

    The  Company  shares  office   facilities  and  has  common  management  and
    directorships with a number of public and private corporate related parties.
    The Company is charged for office rentals and  administrative  services on a
    proportional  cost  basis.  Management  believes  that the  methods  of cost
    allocations and resultant costs are reasonable. Accounts with companies with
    common management and directorships,  management and directors are unsecured
    with no fixed terms of interest or repayment.

5.  SHARE CAPITAL

    a.  Authorized

        50,000,000 common shares with a par value of $0.001 per share


<PAGE>


                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




5.      SHARE CAPITAL (CONTINUED)

<TABLE>
<CAPTION>

    b.  Common Shares Issued                                                                  SHARES           CONSIDERATION
                                                                                              ------           -------------

<S>                                                                                       <C>                 <C>
           Shares of Praxis Pharmaceuticals Inc. (a Nevada corporation) issued for cash          5,000,000    $         5,000
           and exchanged for shares of Micronetics, Inc.
           Outstanding shares of  Micronetics, Inc. at date of acquisition with a                  100,202                  1
           nominal value
           For reorganization costs                                                                305,403             30,540
                                                                                          ----------------    ---------------
           Balance at completion of business re-organization                                     5,405,605             35,541
           For cash                                                                              1,298,783            257,725
           For services                                                                          3,099,832            249,207
           For debenture conversion                                                                617,989             50,000
           For research agreement amendment                                                        300,000             45,000
                                                                                          ----------------    ---------------

           Balance at May 31, 1999                                                              10,722,209    $       637,473
                                                                                          ================    ===============
</TABLE>



    c.  Convertible Debentures

        During  the year,  the  Company  issued  $100,000  of 8% Series A senior
        subordinated  convertible  redeemable  debentures  due August 26,  1999.
        Interest was payable  monthly by the issue of common shares,  commencing
        September 26, 1998.  The debenture was  convertible to common shares and
        the  Company had the option to redeem the  debentures  by paying 125% of
        the principal balance.

        The  debenture  holder  converted  $50,000 to 617,989  common shares and
        principal of $50,000 was redeemed for cash. The debenture  holder waived
        the interest and redemption premium.



<PAGE>


                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




5.  SHARE CAPITAL (CONTINUED)

    d.  Share Issue Commitments

        The  Company  has granted  stock  options to a corporate  third party as
        follows:

            250,000  shares at $0.20 per  share  (subsequently  exercised)
            250,000 shares at $0.40 per share (subsequently exercised)

        The  options  have been  granted to acquire  shares of the  Company at a
        price  greater than the quoted  market price of the stock on the date of
        the grant.  The Company  does not  recognize  an expense for services in
        accounting for the granting or exercise of the option.

    e.  Share Subscriptions and Subsequent Events

        Share  subscriptions of $30,000 were received at May 31, 1999 to acquire
        600,000 common shares (subsequently issued) at $0.05 per share.

        The Company's  shareholders  have approved a share  consolidation of one
        new for five old common shares, effective September 16, 1999.

6.  INCOME TAXES

    The Company has  incurred  operating  losses  which are  available to reduce
    future  years'  taxable   income.   As  at  May  31,  1999,  tax  losses  of
    approximately  $599,000  were  incurred by different  companies in different
    jurisdictions.  These losses are available for carry forward but may only be
    available for offset in specific jurisdictions. No future benefits have been
    recognized in the accounts.

7.  PHARMACEUTICAL RESEARCH AND DEVELOPMENT AGREEMENTS

    The Company has entered into a research and  development  agreement  with an
    Australian  corporate third party subject to common management.  In exchange
    for the funding of research and development of pharmaceutical  products, the
    Company acquires the right of first refusal to obtain exclusive  licences to
    the products.  The public  company will receive a 4% royalty on net sales of
    licenced products by the Company.



<PAGE>


                           PRAXIS PHARMACEUTICALS INC.

                          (FORMERLY MICRONETICS, INC.)
                          (A DEVELOPMENT STAGE COMPANY)

                 NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

                                  MAY 31, 1999
                           (EXPRESSED IN U.S. DOLLARS)




7.  PHARMACEUTICAL RESEARCH AND DEVELOPMENT AGREEMENTS (CONTINUED)

    The Company has entered into an agreement,  effective September 30, 1999, to
    grant a  world-wide  sub-licence  for certain  products to a public  company
    third party under common  management.  In exchange for the sub-licence,  the
    Company is to receive 260,000 shares,  representing a 24% ownership interest
    at the  closing  date of the  agreement.  The third  party will also pay the
    Company  $250,000  ($112,500 paid) to reimburse the Company for research and
    development costs incurred.

8.  SEGMENTED INFORMATION

    a.  Cash

        The Company maintains its cash balance in U.S.,  Canadian and Australian
        currencies.  At the  year  end,  the  U.S.  dollar  equivalents  were as
        follows.


                                                    1999                1998
                                                    ----                ----


        U.S. dollars                         $        13,339     $        19,965
        Australian dollars                            90,174                   -
        Canadian dollars                                   -               3,290
                                             ---------------     ---------------
                                             $       103,513     $        23,255
                                             ===============     ===============

<TABLE>

    b.  Geographic Segments
<CAPTION>

                                                                       DOMESTIC            FOREIGN              TOTAL

<S>                                                                <C>                 <C>                 <C>
        Net loss for the year                                      $        393,118    $        137,456    $        530,574
                                                                   ================    ================    ================
        Assets - current                                           $        13,339     $        90,174     $        103,513
                                                                   ================    ================    ================
</TABLE>

        The  Company's  activities  are all in the ore  industry  segment of the
        research and development of pharmaceutical products.

<PAGE>



                                   EXHIBIT 2.1

                 STOCK EXCHANGE AGREEMENT WITH MICRONETICS, INC.


<PAGE>

                            STOCK EXCHANGE AGREEMENT


THIS AGREEMENT is made this 20th day of June,  1998, by and between  MICRONETICS
INC.,  a Utah  corporation  ("MKRO"),  PRAXIS  PHARMACEUTICALS  INC.,  a  Nevada
corporation  ("PPI"),  the  shareholders  of MKRO who are  listed on  Schedule A
attached  hereto  ("MKRO  SHAREHOLDERS"),  and the  shareholders  of PPI who are
listed on Schedule B attached hereto ("PPI SHAREHOLDERS").

                                   WITNESSETH:

WHEREAS, the total authorized capital stock of PPI consists of 50,000,000 shares
of common stock, each with par value $0.001 par value, of which 5,000,000 shares
are issued and outstanding (the "PPI Shares"), and 1,000,000 shares of preferred
stock, each with $0.01 par value, of which none is issued and outstanding; and

WHEREAS,  the total  authorized  capital  stock of MKRO  consists of  50,000,000
shares of $0.001 par value  Common Stock of which  14,125,500  shares are issued
and outstanding; and

WHEREAS, MKRO desires to acquire all of the issued and outstanding capital stock
of PPI,  or  5,000,000  shares of Common  Stock  ("PPI  Shares")  for  5,000,000
post-split shares of common stock of MKRO; and

WHEREAS,   in   reliance   on  and   subject   to  the  terms  and   conditions,
representations,  warranties,  covenants and agreements  herein  contained,  PPI
desires to sell the PPI Shares to MKRO,  and MKRO  desires to  purchase  the PPI
Shares in a stock for stock exchange.

NOW,  THEREFORE,  in  consideration  of the premises and mutual covenants herein
contained,  and for other  good and  valuable  consideration,  the  receipt  and
sufficiency  of which are  hereby  acknowledged,  the  parties  hereto  agree as
follows:

1.       PURCHASE AND SALE

Section 1.1  AGREEMENT TO PURCHASE AND  EXCHANGE.  In reliance on and subject to
the terms,  conditions,  representations,  warranties,  covenants and agreements
herein  contained,  PPI shall  assign,  transfer and convey unto MKRO,  and MKRO
shall purchase all of the PPI Shares for 5,000,000  post-split shares of MKRO in
a tax free reorganization.

Section 1.2 PURCHASE PRICE. The aggregate purchase price for the PPI Shares (the
"Purchase Price") shall be 5,000,000 post-split MKRO shares.

Section  1.3  CLOSING.  The  closing  of the  transaction  contemplated  in this
Agreement (the "Closing")  shall take place at the offices of John Holt Smith of
Inman  Steinberg Nye & Stone,  1925 Century Park East,  Suite 1600, Los Angeles,
California  90067,  on June 22,  1998,  or at such other date,  time or place as
shall be mutually acceptable to the parties (the "Closing Date").

Section 1.4 TRANSACTIONS AND DOCUMENTS AT AND AFTER CLOSING.

(a)  At the  Closing,  PPI  shall  deliver  to  MKRO  certificates  representing
5,000,000 shares of PPI, duly endorsed for transfer.

                                        1
<PAGE>

(b) At the  Closing,  MKRO shall  deliver to PPI the shares of MKRO common stock
representing  the Purchase Price for the PPI Shares,  as set forth  hereinabove,
and bearing an appropriate legend restricting transfer except as permitted under
Rule 144 of the Securities Act of 1933, as amended.

(c) From time to time and at any time,  at MKRO's  request,  whether on or after
the Closing  Date,  and without  further  consideration,  PPI shall,  at its own
expense except as otherwise provided in this Agreement, execute and deliver such
further documents and instruments of conveyance and transfer and shall take such
further actions as may be necessary or convenient,  in the reasonable opinion of
MKRO,  to transfer and convey to MKRO,  all of its right,  title and interest in
and to the PPI Shares, free and clear of any lien or adverse claim.

(d) From time to time and at any time, at PPI's request, whether on or after the
Closing Date, and without further consideration,  MKRO shall, at its own expense
except as otherwise provided in this Agreement, execute and deliver such further
documents and instruments of conveyance and transfer and shall take such further
actions as may be necessary or convenient,  in the reasonable opinion of PPI, to
transfer and convey to PPI,  all of its right,  title and interest in and to the
MKRO Shares, free and clear of any lien or adverse claim.

2.       ADDITIONAL AGREEMENTS.

Section 2.1 MKRO'S ACCESS AND  INSPECTION.  PPI has allowed and shall allow MKRO
and its authorized representatives full access during normal business hours from
and  after  the  date  hereof  and  prior  to the  Closing  Date to all of PPI's
properties, books, contracts,  commitments and records for the purpose of making
such  investigation  as  MKRO  may  desire,  and PPI  shall  furnish  MKRO  such
information  concerning  PPI's  affairs as MKRO may request.  PPI has caused and
shall cause PPI's  personnel  to assist  MKRO in making such  investigation  and
shall  cause  the  counsel,   accountants,   engineers  and  other  non-employee
representatives of PPI to be reasonably available to MKRO for such purposes.

Section 2.2 PPI'S ACCESS AND INSPECTION. MKRO shall allow PPI and its authorized
representatives  access  during  normal  business  hours from and after the date
hereof  and  prior to the  Closing  Date to such of  MKRO's  properties,  books,
contracts, commitments and records as PPI may reasonably request for the purpose
of determinng the financial condition of MKRO, MKRO shall cause MKRO's personnel
to assist  PPI in  making  such  investigation  and  shall  cause  the  counsel,
accountants,  engineers  and other  non-employee  representatives  of MKRO to be
reasonably available to PPI for such purposes.

Section 2.3  COOPERATION.  The parties shall cooperate fully with each other and
with their representatives, counsel and accountants in connection with any steps
required  to be  taken  as part  of  their  respective  obligations  under  this
Agreement,  and will use their  best  efforts  to  consummate  the  transactions
contemplated hereby and fulfil their obligations hereunder.

Section 2.4 EXPENSES.  All of the expenses  incurred by MKRO in connection  with
the authorization,  preparation,  execution and performance of this Agreement by
MKRO,   including   without   limitation   all  fees  and  expenses  of  agents,
representatives,  counsel and accountants for MKRO, shall be paid by MKRO and/or
its  representatives.  All  expenses  incurred  by PPI in  connection  with  the
authorization,   preparation,  execution  and  performance  of  this  Agreement,
including without  limitation all fees and expenses of agents,  representatives,
counsel and accountants, shall be paid by PPI.

Section 2.5 BROKERS.  Each party hereto  jointly and  severally  represents  and
warrants  that no broker or finder  has acted on its behalf in  connection  with
this  Agreement  or  the  transactions   contemplated  herein  other  than  Type
Investments  Holdings Ltd., Aspen Ridge Corporation and Satisfaction  Trust, and
each party  shall  indemnify  the other and save it  harmless  from any claim or
demand for commission or other

                                        2
<PAGE>

compensation  by any  broker,  finder or  similar  agent  claiming  to have been
employed by or on behalf of such party.

Section 2.6 MKRO SALE OF SUBSIDIARIES. Prior to the Closing, MKRO shall sell its
two subsidiaries, Information Management Systems Inc. and Telesolutions Inc., to
a private company owned or controlled by Juan Ledo in exchange for  cancellation
of 4,445,000 shares of MKRO Common Stock in the name of Juan Ledo.

Section 2.7 REVERSE SPLIT. Prior to Closing,  the Board of Directors of MKRO and
the  requisite  number of  shareholders  shall  approve and effect a 1-to-118.45
reverse split of the Common Stock of MKRO.

3.       REPRESENTATIONS AND WARRANTIES OF PPI.

PPI represents, covenants and warrants to MKRO as follows:

Section 3.1 CORPORATE  EXISTENCE/STANDING/AUTHORITY.  PPI is a corporation  duly
organized,  validly  existing and in good standing  under the laws of Nevada and
has the corporate  power and authority to own,  operate and lease its respective
properties,  to carry on its business as now being conducted,  and to enter into
this Agreement and to carry out the  transactions  contemplated  hereby.  PPI is
duly qualified to do business and is in good standing in each jurisdiction where
the  failure to qualify  would  have a  material  adverse  affect on it. PPI has
delivered  to MKRO or its  counsel  true and correct  copies of the  articles of
incorporation and by-laws of PPI, together with any amendments thereto.

Section 3.2 SHARES OF STOCK. All issued and outstanding  shares of capital stock
of PPI have been duly  authorized  and  validly  issued  and are fully  paid and
nonassessable. There is no subscription, option, warrant, call, right, contract,
commitment,  understanding  or  arrangement  relating to the  issuance,  sale or
transfer  by PPI of any  shares of its  capital  stock,  including  any right of
conversion or exchange under any outstanding security or other instrument.

Section 3.3  AUTHORITY.  PPI has the full right and  authority to enter into and
fully  perform  this  Agreement  and all other  agreements  and  documents to be
delivered to MKRO in connection  herewith.  All actions  required to be taken by
PPI to authorize the execution,  delivery and  performance of this Agreement and
all other  agreements and documents to be delivered in connection  herewith have
been or will by the Closing Date be properly taken.  This Agreement  constitutes
the valid and binding  obligation of PPI.  Neither the execution and delivery of
this  Agreement and all other  agreements  and documents  executed in connection
herewith nor the  consummation of the transactions  contemplated  hereby nor the
performance of this Agreement and all other agreements and documents executed in
connection  herewith  will  (1)  conflict  with or  result  in a  breach  of any
provision of the  certificate of  incorporation  or by-laws of PPI, (2) violate,
conflict  with,  or result  in a breach of any  provision  of, or  constitute  a
default  (or an event  which,  with  notice  or  lapse  of time or  both,  would
constitute  a  default)  under,  or result in the  termination  or in a right of
termination or cancellation  of, or accelerate the performance or the payment of
money  required  by, or result in the creation of any lien,  security  interest,
charge or  encumbrance  upon any of PPI's  properties  under  any of the  terms,
conditions or provisions of any loan agreement, note, bond, mortgage, indenture,
lease,  agreement or other  instrument or commitment to which PPI is a party, or
by which PPI or its  properties  may be bound or  affected  or (3)  violate  any
order,  writ,  injunction,   decree,   judgment,  or  ruling  of  any  court  or
governmental authority specifically applicable to PPI or any of its properties.

Section  3.4 NO  VIOLATION.  Except as set forth on  Schedule  3.4,  to the best
knowledge of PPI, PPI has complied with all rules,  regulations,  codes and laws
affecting  its  business  and  operations  and is not in  default  under,  or in
violation  of, any  provision of any federal,  state or local rule,  regulation,
code or law nor has PPI been given notice of any such default or violation.

                                        3
<PAGE>

Section 3.5  LICENSES  AND RIGHTS.  PPI  possesses  all  franchises,  easements,
licenses,  permits and other  authorizations  from  governmental  or  regulatory
authorities  and from all other persons or entities that are necessary to permit
it to engage in its business as presently  conducted in and at all locations and
places where it is presently operating. Such franchises,  licenses,  permits and
other authorizations are set forth on Schedule 3.5.

Section 3.6 CONSENTS. Except as set forth on Schedule 3.6 hereto, no approval or
consent of any person,  firm or other  entity or body is required to be obtained
by PPI for the authorization of this Agreement or the consummation by PPI of the
transactions contemplated hereby.

Section  3.7 NO  DEFAULTS.  Except as set  forth on  Schedule  3.7,  to the best
knowledge  of PPI,  no default  (or event  which with the passage of time or the
giving of notice or both would  become a default)  exists or is alleged to exist
with respect to the  performance of any obligation of PPI under the terms of any
indenture,  license,  mortgage,  deed of trust,  lease, note,  guaranty or other
contract or instrument, including, but not limited to, any contract set forth on
Schedule 3.17, to which PPI is a party or to which its assets are subject, or by
which it is otherwise  bound,  and no such default or event exists or is alleged
to exist with respect to the  performance  of any  obligation of any other party
thereto.

Section 3.8 FINANCIAL  STATEMENTS.  MKRO has been or will be furnished  with the
proforma  financial  statements  (the  "Financial  Statements").  The  Financial
Statements  were  prepared in  accordance  with  generally  accepted  accounting
principles and present fairly and accurately the information set forth therein.

Section 3.9  ABSENCE OF CERTAIN  CHANGES.  Except as set forth on  Schedule  3.9
hereto,  since December 31, 1997, PPI has actively conducted its business in the
ordinary and regular  course.  Since that date,  there has not been any material
adverse  change in condition  (financial or  otherwise),  results of operations,
assets, liabilities,  properties,  business or prospects of PPI nor is any event
threatened which would cause such an adverse change,  nor has there occurred any
event or governmental regulation or order restricting the business of PPI.

Section 3.10 FACILITIES AND EQUIPMENT.  The personal property owned or leased by
PPI at its  facility  for the  operation  of, or used in, its business is in its
possession  or under its  control  and is  adequate  for the  operation  of such
business as presently conducted.

Section  3.11 TITLE TO ASSETS.  Except as set forth on  Schedule  3.11 or in the
Financial  Statements,  PPI has good,  valid and marketable  title to all of its
real property and leasehold estates and good and valid title to all of its other
assets (tangible and intangible),  including,  but not limited to, all leasehold
improvements  and equipment  and all other  properties  and assets  reflected or
required to be reflected in the  Financial  Statements  and all  properties  and
assets  purchased or leased by it since the dates of such  Financial  Statements
(except for properties and assets so reflected or required to be reflected which
have been sold or  otherwise  disposed of in the ordinary  course of  business),
subject  to no liens,  pledges,  encumbrances,  mortgages,  security  interests,
charges or other similar  restrictions of any nature  whatsoever.  Except as set
forth on  Schedule  3.11,  PPI  enjoys  peaceful  and  quiet  possession  of its
properties and assets pursuant to or by all of the deeds, bills of sale, leases,
licenses and other agreements under which it is operating its business.

Section 3.12 ABSENCE OF UNDISCLOSED LIABILITIES.  PPI does not have any material
liabilities or  obligations,  either accrued or unaccrued,  fixed or contingent,
which  have not been  reflected  in the  Financial  Statements  or set  forth on
Schedule 3.12 hereof.

Section  3.13  LITIGATION.  Schedule  3.13  hereof  sets  forth  a  list  of all
administrative  or judicial  proceedings to which PPI is a party.  Except as set
forth on Schedule 3.13, there is no action, suit, claim, demand,  arbitration or
other proceeding,  administrative or judicial, pending or, to the best knowledge
of PPI,

                                        4
<PAGE>

threatened  against  or  relating  to PPI  which,  if  adversely  determined  or
resolved, would materially and adversely affect the financial condition, results
of operations, business or prospects of PPI.

Section 3.14      PATENTS AND TRADEMARKS.

(a) Except as set forth on Schedule 3.14(a), PPI does not own, or operate under,
any patent,  trademark or service mark or any applications  therefor.  All trade
names  (including those whose use is limited to one or more states of the United
States)  owned or used by PPI are listed on  Schedule  3.14  hereof  and, to the
extent  indicated  therein,  have been duly  registered  with the  states of the
United States or the  corresponding  offices of other  countries.  Except as set
forth on Schedule 3.14, PPI is the sole and exclusive  owner of, or has the sole
and exclusive power with respect to, or has the sole and exclusive right to use,
the trade names specified on Schedule 3.14.

(b)  Except  as set  forth on  Schedule  3.14(b)  hereof,  PPI has not ever been
charged with  infringement or violation of any adversely held  trademark,  trade
name or copyright.

(c) Except as set forth on Schedules 3.14(a) and 3.14(b), there are no claims or
demands of any other person, firm or corporation  pertaining to the trade names,
copyright registrations or pending copyright registration  applications,  as the
case may be, listed on such schedules,  and no proceedings  have been instituted
which challenge the right of PPI in respect thereof.

Section 3.15      EMPLOYEE BENEFITS.

(a) Schedule 3.15 hereof  contains a list of (i) each pension,  profit  sharing,
bonus,  deferred  compensation,  or other retirement plan or arrangement for the
benefit  of any  employee  or  group  of  employees  of  PPI or any  independent
contractors  or group of  independent  contractor  of PPI,  (ii)  each  medical,
health,  disability,  insurance or other plan or  arrangement  of PPI, and (iii)
each  employee  stock  option plan or other plan  providing  for the purchase of
shares of capital  stock of PPI. All of such plans and  arrangements  of PPI are
referred to herein as the "employee benefit plans".

(b)  The  amounts  reflected  in the  Financial  Statements  as  liabilities  or
contingent  liabilities  with  respect  to  employee  benefit  plans  have  been
calculated  in  accordance  and  compliance  with   applicable  law,   including
accounting principles relating thereto.

(c) All of the employee benefit plans maintained by PPI (and each funding medium
which may be attendant  thereto) are in compliance  with  applicable law and all
reporting and disclosure requirements under applicable laws and regulations, and
have  been  administered  and  operated  in  accordance  with  their  respective
provisions and applicable law. There are no actions, suits or claims (other than
routine claims for benefits) pending with respect to the employee benefit plans.

(d) PPI has filed, published and disseminated all reports, documents, statements
and  communications  which are required to be filed,  published or  disseminated
under  applicable  law and the  rules  and  regulations  promulgated  thereunder
relating  to, and have  timely made all  modifications  and  amendments  to, the
employee benefit plans.

Section 3.16 TAXES AND TAX RETURNS. PPI has duly filed all income, franchise and
other tax returns  and  reports  required to be filed by it and has duly paid or
made  provision  for  the  payment  of all  taxes  (including  any  interest  or
penalties) which are due and payable pursuant to such returns.  PPI has withheld
proper and accurate  amounts from their  employees'  compensation in substantial
compliance with all withholding and similar  provisions of applicable law. There
are and will hereafter be no tax deficiencies (including penalties and interest)
of any kind assessed  against PPI with respect to any period ending on or before
the Closing Date.

                                        5
<PAGE>

Section 3.17 CONTRACTS. PPI has heretofore furnished to MKRO or its counsel true
and complete  copies of each  document,  and a written  description of each oral
contact, set forth on Schedule 3.17 hereof. Schedule 3.17 is a true and complete
list of all contracts, understandings,  commitments, arrangements and agreements
of the following types, including all amendments thereto which PPI is a party:

(a) Contracts  relating to equipment  purchases,  or series of similar equipment
purchases  from the same  supplier,  involving  an  expenditure  of,  or if in a
series, expenditures in the aggregate of, more than twenty-five thousand dollars
($25,000);

(b)  Bonus,  incentive,  pension,  profit-sharing,  hospitalization,  insurance,
deferred  compensation,  retirement,  stock  option or stock  purchase  plans or
similar plans providing employee benefits;

(c) Factoring,  loan, note,  financing or similar  contracts with any lenders or
guarantees of  undertakings  to answer for the debts or defaults of another,  or
any contracts encumbering title to any properties, involving in each case, or if
in a series  involving the same lender,  guarantor or property,  as the case may
be, in the aggregate, at least twenty-five thousand dollars ($25,000);

(d) contracts for the acquisition or disposition of a business or  substantially
all of the property,  assets or capital stock or other  securities of a business
or company under which there are  continuing or  unperformed  obligations on the
part of any of the parties hereto, which contracts in each case involve at least
twenty-five thousand dollars($25,000);

(e) Conditional  sales contracts,  leases of personal  property or contracts for
the  purchase or sale of real or personal  property,  involving  in each case at
least twenty-five thousand dollars ($25,000);

(f) Management or consulting  contracts  involving in each case, or with respect
to any  individual  in the  aggregate,  at least  twenty-five  thousand  dollars
($25,000);

(g) contracts for the furnishing of services or products to or by PPI, involving
an expenditure in each case of at least twenty-five thousand dollars ($25,000);

(h) Royalty or licensing  contracts or contracts  requiring  similar payments to
unrelated  parties  individually,  or with respect to any unrelated party in the
aggregate,  involving or which reasonably may in the future involve an amount in
excess of twenty-five thousand dollars ($25,000) annually;

(i) All employment agreements between PPI and any of its employees; and

(j) All  agreements,  contracts and commitments not listed on any other schedule
hereto which  individually  involve the payment of twenty-five  thousand dollars
($25,000) or more.

Except  as set  forth on  Schedule  3.17,  all such  contracts,  understandings,
commitments, arrangements and agreements are in full force and effect.

Section 3.18 COLLECTIVE BARGAINING AGREEMENTS. Schedule 3.18 hereof is a list of
all collective bargaining agreements with any labor organization to which PPI is
a party.  The  relations  of PPI with its  employees  are good and  there are no
impending labor difficulties.

Section 3.19 INSURANCE.  PPI is insured by insurers unaffiliated with PPI or PPI
with respect to its  properties  and the conduct of its business in such amounts
and against such risks as are generally and prudently  maintained for comparable
businesses and consistent with its past practice.


                                        6
<PAGE>

Section 3.20      REAL PROPERTY.

(a)  Schedule  3.20 hereof sets forth a true and  complete  list of (i) all real
property owned by PPI and (ii) all real property leases to which PPI is a party.
PPI has heretofore  furnished to MKRO or its counsel true and complete copies of
each written contract and a written  description of each oral contract  relating
to the list set forth on Schedule 3.20.

(b) With respect to the leases  described on Schedule 3.20,  except as set forth
on Schedule 3.20:

         (i) All such  leases  are in  writing  and duly  executed,  and,  where
required,  witnessed,  acknowledged  and recorded to make them valid and binding
and in full  force  and  effect  for the full term  thereof,  and none have been
modified;

         (ii) The rental set forth in each such lease is the actual rental being
paid, and there are no separate agreements or understandings with respect to the
same not set forth in Schedule 3.20;

         (iii) The lessee  under each such lease has the full right to  exercise
any renewal option  contained  therein and upon due exercise will be entitled to
enjoy the use of the premises for the full term of such renewal option;

         (iv) Upon  performance  by the lessee of the terms of each such  lease,
the  lessee  has  the  full  right  to  enjoy  the use of the  premises  demised
thereunder for the full term thereof; and

         (v)  Except  as set  forth on  Schedule  3.20,  all  security  deposits
required by such leases have been made and no  forfeiture  with respect  thereto
claimed, in whole or in part, by any of the lessors.

Section  3.21  MATERIAL  MISSTATEMENTS  OR  OMISSIONS.   No  representations  or
warranties made by PPI under this Agreement or in any  certificate,  schedule or
other  document  furnished or to be  furnished  to MKRO or its counsel  pursuant
hereto,  or in connection with the transactions  contemplated by this Agreement,
contains or will contain any untrue  statement of a material  fact,  or omits or
will omit to state a material  fact  necessary  to make the  statements  of fact
contained therein not misleading.

4.       REPRESENTATIONS AND WARRANTIES OF MKRO

MKRO represents, covenants and warrants to PPI as follows:

Section 4.1 CORPORATE  EXISTENCE/STANDING/AUTHORITY.  MKRO is a corporation duly
organized,  validly existing and in good standing under the laws of Utah and has
the  corporate  power and  authority  to own,  operate and lease its  respective
properties,  to carry on its business as now being conducted,  and to enter into
this Agreement and to carry out the transactions  contemplated  hereby.  MKRO is
duly qualified to do business and is in good standing in each jurisdiction where
the  failure to qualify  would have a material  adverse  affect on it.  MKRO has
delivered  to PPI or its  counsel  true and  correct  copies of the  articles of
incorporation and by-laws of MKRO, together with any amendments thereto.

Section 4.2 SHARES OF STOCK.  MKRO has  authorized  50,000,000  shares of common
stock of which there are presently issued and outstanding  18,000,000  shares of
common stock.  None of the shares of preferred stock are issued and outstanding.
All  issued  and  outstanding  shares  of  capital  stock of MKRO have been duly
authorized and validly issued and are fully paid and nonassessable.  There is no
subscription, option, warrant, call, right, contract, commitment,  understanding
or arrangement relating to the issuance,  sale or transfer by MKRO of any shares
of its capital  stock,  including any right of conversion or exchange  under any
outstanding  security  or other  instrument.  There  is on file  with the NASD a
current,  accurate and complete 15-c2(11) for MKRO and MKRO is currently trading
on the Bulletin Board under the Symbol "MKRO."

                                        7
<PAGE>

Section 4.3  AUTHORITY.  MKRO has the full right and authority to enter into and
fully  perform  this  Agreement  and all other  agreements  and  documents to be
delivered to PPI in  connection  herewith.  All actions  required to be taken by
MKRO to authorize the execution,  delivery and performance of this Agreement and
all other  agreements and documents to be delivered in connection  herewith have
been or will by the Closing Date be properly taken.  This Agreement  constitutes
the valid and binding  obligation of MKRO. Neither the execution and delivery of
this  Agreement and all other  agreements  and documents  executed in connection
herewith nor the  consummation of the transactions  contemplated  hereby nor the
performance of this Agreement and all other agreements and documents executed in
connection  herewith  will  (1)  conflict  with or  result  in a  breach  of any
provision of the certificate of  incorporation  or by-laws of MKRO, (2) violate,
conflict  with,  or result  in a breach of any  provision  of, or  constitute  a
default  (or an event  which,  with  notice  or  lapse  of time or  both,  would
constitute  a  default)  under,  or result in the  termination  or in a right of
termination or cancellation  of, or accelerate the performance or the payment of
money  required  by, or result in the creation of any lien,  security  interest,
charge or  encumbrance  upon any of MKRO's  properties  under any of the  terms,
conditions or provisions of any loan agreement, note, bond, mortgage, indenture,
lease,  agreement or other instrument or commitment to which MKRO is a party, or
by which MKRO or its  properties  may be bound or  affected  or (3)  violate any
order,  writ,  injunction,   decree,   judgment,  or  ruling  of  any  court  or
governmental authority specifically applicable to MKRO or any of its properties.

Section  4.4 NO  VIOLATION.  Except as set forth on  Schedule  4.4,  to the best
knowledge of MKRO, MKRO has complied with all rules, regulations, codes and laws
affecting  its  business  and  operations  and is not in  default  under,  or in
violation  of, any  provision of any federal,  state or local rule,  regulation,
code or law nor has MKRO been given notice of any such default or violation.


<PAGE>



Section 4.5 LICENSES  AND RIGHTS.  MKRO  possesses  all  franchises,  easements,
licenses,  permits and other  authorizations  from  governmental  or  regulatory
authorities  and from all other persons or entities that are necessary to permit
it to engage in its business as presently  conducted in and at all locations and
places where it is presently operating. Such franchises,  licenses,  permits and
other authorizations are set forth on Schedule 4.5.

Section 4.6 CONSENTS. Except as set forth on Schedule 4.6 hereto, no approval or
consent of any person,  firm or other  entity or body is required to be obtained
by MKRO for the  authorization  of this Agreement or the consummation by MKRO of
the transactions contemplated hereby.

Section  4.7 NO  DEFAULTS.  Except as set  forth on  Schedule  4.7,  to the best
knowledge  of MKRO,  no default  (or event which with the passage of time or the
giving of notice or both would  become a default)  exists or is alleged to exist
with respect to the performance of any obligation of MKRO under the terms of any
indenture,  license,  mortgage,  deed of trust,  lease, note,  guaranty or other
contract or instrument, including, but not limited to, any contract set forth on
Schedule  4.17, to which MKRO is a party or to which its assets are subject,  or
by which it is  otherwise  bound,  and no such  default  or event  exists  or is
alleged to exist with respect to the  performance of any obligation of any other
party thereto.

Section  4.8  FINANCIAL  STATEMENTS.  PPI has  been or  will be  furnished  with
statement of  liabilities  of MKRO for the period ended April 30, 1998,  and its
statements  of  earnings  for  the  fiscal  year  then  ended  (the   "Financial
Statements")  as set  forth on  Schedule  4.8  attached  hereto.  The  Financial
Statements  were  prepared in  accordance  with  generally  accepted  accounting
principles applied on a basis consistent with prior periods and as of their date
of issuance were or will be true,  correct and complete in all material respects
and present fairly and accurately the information set forth therein.

Section 4.9  ABSENCE OF CERTAIN  CHANGES.  Except as set forth on  Schedule  4.9
hereto, since December 31, 1997, MKRO has actively conducted its business in the
ordinary and regular  course.  Since that date,  there has not been any material
adverse change in the condition (financial or otherwise), results of

                                        8
<PAGE>

operations, assets, liabilities,  properties,  business or prospects of MKRO nor
is any event threatened which would cause such an adverse change,  nor has there
occurred any event or governmental  regulation or order restricting the business
of MKRO.

Section 4.10 FACILITIES AND EQUIPMENT.  The personal property owned or leased by
MKRO at its  facility for the  operation  of, or used in, its business is in its
possession  or under its  control  and is  adequate  for the  operation  of such
business as presently conducted.

Section  4.11 TITLE TO ASSETS.  Except as set forth in  Schedule  4.11 or in the
Financial  Statements,  MKRO has good,  valid and marketable title to all of its
real property and leasehold estates and good and valid title to all of its other
assets (tangible and intangible),  including,  but not limited to, all leasehold
improvements  and equipment  and all other  properties  and assets  reflected or
required to be reflected in the  Financial  Statements  and all  properties  and
assets  purchased or leased by it since the dates of such  Financial  Statements
(except for properties and assets so reflected or required to be reflected which
have been sold or  otherwise  disposed of in the ordinary  course of  business),
subject  to no liens,  pledges,  encumbrances,  mortgages,  security  interests,
charges or other similar  restrictions of any nature  whatsoever.  Except as set
forth on  Schedule  4.11,  MKRO  enjoys  peaceful  and quiet  possession  of its
properties and assets pursuant to or by all of the deeds, bills of sale, leases,
licenses and other agreements under which it is operating its business.

Section 4.12 ABSENCE OF UNDISCLOSED LIABILITIES. MKRO does not have any material
liabilities or  obligations,  either accrued or unaccrued,  fixed or contingent,
which  have not been  reflected  in the  Financial  Statements  or set  forth on
Schedule 4.12 hereof, or which exceed in the aggregate $25,000.

Section  4.13  LITIGATION.  Schedule  4.13  hereof  sets  forth  a  list  of all
administrative or judicial  proceedings to which MKRO is a party.  Except as set
forth on Schedule 4.13, there is no action, suit, claim, demand,  arbitration or
other proceeding,  administrative or judicial, pending or, to the best knowledge
of MKRO,  threatened against or relating to MKRO which, if adversely  determined
or resolved,  would  materially  and adversely  affect the financial  condition,
results of operations, business or prospects of MKRO.

Section 4.14      PATENTS AND TRADEMARKS.

(a)  Except as set forth on  Schedule  4.14(a),  MKRO does not own,  or  operate
under, any patent,  trademark or service mark or any applications  therefor. All
trade names  (including  those whose use is limited to one or more states of the
United  States) owned or used by MKRO are listed on Schedule 4.14 hereof and, to
the extent indicated  therein,  have been duly registered with the states of the
United States or the  corresponding  offices of other  countries.  Except as set
forth on Schedule 4.14, MKRO is the sole and exclusive owner of, or has the sole
and exclusive power with respect to, or has the sole and exclusive right to use,
the trade names specified on Schedule 4.14.

(b)  Except as set forth on  Schedules  4.14(b)  hereof,  MKRO has not ever been
charged with  infringement or violation of any adversely held  trademark,  trade
name or copyright.

(c) Except as set forth on Schedules 4.14(a) and 4.14(b), there are no claims or
demands of any other person, firm or corporation  pertaining to the trade names,
copyright registrations or pending copyright registration  applications,  as the
case may be, listed on such schedules,  and no proceedings  have been instituted
which challenge the right of MKRO in respect thereof.


                                        9
<PAGE>

Section 4.15      EMPLOYEE BENEFITS.

(a) Schedule 4.15 hereof  contains a list of (i) each pension,  profit  sharing,
bonus,  deferred  compensation,  or other retirement plan or arrangement for the
benefit  of any  employee  or  group  of  employees  of MKRO or any  independent
contractors  or group of  independent  contractor  of MKRO,  (ii) each  medical,
health,  disability,  insurance or other plan or  arrangement of MKRO, and (iii)
each  employee  stock  option plan or other plan  providing  for the purchase of
shares of capital stock of MKRO. All of such plans and  arrangements of MKRO are
referred to herein as the "employee benefit plans".

(b)  The  amounts  reflected  in the  Financial  Statements  as  liabilities  or
contingent  liabilities  with  respect  to  employee  benefit  plans  have  been
calculated  in  accordance  and  compliance  with   applicable  law,   including
accounting principles relating thereto.

(c) All of the  employee  benefit  plans  maintained  by MKRO (and each  funding
medium which may be attendant thereto) are in compliance with applicable law and
all reporting and disclosure requirements under applicable laws and regulations,
and have been  administered  and operated in  accordance  with their  respective
provisions and applicable law. There are no actions, suits or claims (other than
routine claims for benefits) pending with respect to the employee benefit plans.

(d)  MKRO  has  filed,  published  and  disseminated  all  reports,   documents,
statements  and  communications  which are  required to be filed,  published  or
disseminated  under  applicable  law and the rules and  regulations  promulgated
thereunder  relating to, and have timely made all  modifications  and amendments
to, the employee benefit plans.

Section  4.16 TAXES AND TAX RETURNS.  MKRO has duly filed all income,  franchise
and other tax returns  and reports  required to be filed by it and has duly paid
or made  provision  for the  payment of all taxes  (including  any  interest  or
penalties) which are due and payable pursuant to such returns. MKRO has withheld
proper and accurate  amounts from their  employees'  compensation in substantial
compliance with all withholding and similar  provisions of applicable law. There
are and will hereafter be no tax deficiencies (including penalties and interest)
of any kind assessed against MKRO with respect to any period ending on or before
the Closing Date.

Section 4.17 CONTRACTS. MKRO has heretofore furnished to PPI or its counsel true
and complete  copies of each  document,  and a written  description of each oral
contact set forth on Schedule 4.17 hereof.  Schedule 4.17 is a true and complete
list of all contracts, understandings,  commitments, arrangements and agreements
of the  following  types,  including all  amendments  thereto to which MKRO is a
party:

(a) Contracts  relating to equipment  purchases,  or series of similar equipment
purchases  from the same  supplier,  involving  an  expenditure  of,  or if in a
series, expenditures in the aggregate of, more than $25,000;

(b)  Bonus,  incentive,  pension,  profit-sharing,  hospitalization,  insurance,
deferred  compensation,  retirement,  stock  option or stock  purchase  plans or
similar plans providing employee benefits;

(c) Factoring,  loan, note,  financing or similar  contracts with any lenders or
guarantees of  undertakings  to answer for the debts or defaults of another,  or
any contracts encumbering title to any properties, involving in each case, or if
in a series  involving the same lender,  guarantor or property,  as the case may
be, in the aggregate, at least $25,000;

(d) Contracts for the acquisition or disposition of a business or  substantially
all of the property,  assets or capital stock or other  securities of a business
or company under which there are  continuing or  unperformed  obligations on the
part of any of the parties hereto, which contracts in each case involve at least
$25,000;

                                       10
<PAGE>

(e) Conditional  sales contracts,  leases of personal  property or contracts for
the  purchase or sale of real or personal  property,  involving  in each case at
least twenty-five thousand dollars ($25,000);

(f) Management or consulting contracts,  involving in each case, or with respect
to  any   individual   in  the   aggregate,   at  least   twenty-five   thousand
dollars($25,000);

(g)  Contracts  for the  furnishing  of  services  or  products  to or by  MKRO,
involving an expenditure in each case of at least  twenty-five  thousand dollars
($25,000);

(h) Royalty or licensing  contracts or contracts  requiring  similar payments to
unrelated  parties  individually,  or with respect to any unrelated party in the
aggregate,  involving or which reasonably may in the future involve an amount in
excess of twenty-five thousand dollars ($25,000) annually;

(i) All employment agreements between MKRO and any of its employees; and

(j) All  agreements,  contracts and commitments not listed on any other schedule
hereto which  individually  involve the payment of twenty-five  thousand dollars
($25,000) or more.

Except  as set  forth on  Schedule  4.17,  all such  contracts,  understandings,
commitments, arrangements and agreements are in full force and effect.

Section 4.18 COLLECTIVE BARGAINING AGREEMENTS. Schedule 4.18 hereof is a list of
all collective  bargaining  agreements with any labor organization to which MKRO
is a party.  The  relations of MKRO with its employees are good and there are no
impending labor difficulties.

Section 4.19 INSURANCE.  MKRO is insured by insurers  unaffiliated  with MKRO or
MKRO with  respect to its  properties  and the  conduct of its  business in such
amounts and against such risks as are  generally and  prudently  maintained  for
comparable businesses and consistent with its past practice.

Section 4.20      REAL PROPERTY.

(a)  Schedule  4.20 hereof sets forth a true and  complete  list of (i) all real
property  owned by MKRO and (ii) all real  property  leases  to which  MKRO is a
party.  MKRO has  heretofore  furnished  to PPI or its counsel true and complete
copies of each written contract and a written  description of each oral contract
relating to the list set forth on Schedule 4.20.

(b) With respect to the leases  described on Schedule 4.20,  except as set forth
on Schedule 4.20:

         (i) All such  leases  are in  writing  and duly  executed,  and,  where
required,  witnessed,  acknowledged  and recorded to make them valid and binding
and in full  force  and  effect  for the full term  thereof,  and none have been
modified;

         (ii) The rental set forth in each such lease is the actual rental being
paid, and there are no separate agreements or understandings with respect to the
same not set forth in Schedule 4.20;

         (iii) The lessee  under each such lease has the full right to  exercise
any renewal option  contained  therein and upon due exercise will be entitled to
enjoy the use of the premises for the full term of such renewal option;

         (iv) Upon  performance  by the lessee of the terms of each such  lease,
the  lessee  has  the  full  right  to  enjoy  the use of the  premises  demised
thereunder for the full term thereof; and

                                       11
<PAGE>

         (v)  Except  as set  forth on  Schedule  4.20,  all  security  deposits
required by such leases have been made and no  forfeiture  with respect  thereto
claimed, in whole or in part, by any of the lessors.

Section  4.20  MATERIAL  MISSTATEMENTS  OR  OMISSIONS.   No  representations  or
warranties made by MKRO under this Agreement or in any certificate,  schedule or
other  document  furnished  or to be  furnished  to PPI or its counsel  pursuant
hereto,  or in connection with the transactions  contemplated by this Agreement,
contains or will contain any untrue  statement of a material  fact,  or omits or
will omit to state a material  fact  necessary  to make the  statements  of fact
contained therein not misleading.

5.       COVENANTS AND TRANSACTIONS PRIOR TO CLOSING

Section 5.1 CONDUCT AND  TRANSACTIONS  OF PPI PRIOR TO THE CLOSING.  Between the
date of this  Agreement  and the Closing,  the  executive  officers and board of
directors  of PPI shall retain full  control of the  management  and business of
their respective  businesses.  In order to assure protection and preservation of
PPI's business as well as PPI's performance of its obligations under and related
to this  Agreement,  PPI agrees that from the date of this  Agreement  up to and
including the Closing:

(a) PPI  shall  give  MKRO,  its  counsel,  accountants,  appraisers  and  other
representatives  or experts retained by MKRO full access on reasonable notice to
all the premises and books,  records and personnel of PPI during normal business
hours and cause PPI to furnish to MKRO such  financial  and  operating  data and
other information with respect to the business and properties of PPI as MKRO may
from  time to time  reasonably  request.  In the  event of  termination  of this
Agreement for any reason, MKRO will return all documents,  work papers and other
materials  obtained  from  PPI or PPI and  will not  further  disclose  to third
parties any confidential information obtained by it pursuant hereto.

(b) PPI shall use all  reasonable  efforts to (i)  preserve  intact the  present
business  organization  and personnel of PPI, (ii) preserve the present goodwill
and advantageous  relationships of PPI with all persons having business dealings
with PPI, and (iii)  preserve and maintain in force all licenses,  certificates,
leases, contracts, permits, registrations, franchises, confidential information,
trade names and copyrights,  and  applications  for any of same, bonds and other
similar rights of PPI. Except as otherwise provided in this Agreement, PPI shall
refrain from entering into any new employment or consulting  agreements with any
of its present  officers,  management  personnel  or  consultants,  or any other
employment or consulting  agreement with any other person, not terminable by PPI
on less than thirty (30) days' notice. PPI shall maintain in force all property,
casualty,  crime,  life,  directors,  officers and other forms of insurance  and
bonds which it presently  carries and,  except with the written consent of MKRO,
no cancellation or assignment of existing insurance coverage will be effected by
PPI.

(c) MKRO shall  operate its  business  only in the usual,  regular and  ordinary
course and manner,  and, except with the written consent of MKRO,  shall refrain
from (i) selling or agreeing  to sell any capital  stock,  or (ii) except in the
ordinary course of business, encumbering or mortgaging any property or assets or
terminating  or modifying any lease or incurring any  obligation  (contingent or
otherwise).

(d) PPI or PPI shall not  discuss or  negotiate  with any third party a possible
sale of all or any part of the capital  shares or assets of PPI, nor provide any
information to any third party with respect thereto, other than such information
which is provided in the  ordinary  course of the  business  operation of PPI to
third parties,  provided PPI has no reason to believe that such  information may
be utilized to evaluate a possible sale of the capital shares or assets of PPI.

(e) PPI will exert its best efforts to fulfill in a timely manner all objectives
and conditions to permit  consummation  of the  transactions  as contemplated by
this Agreement and execute and deliver to MKRO any and all documents  necessary,
in the  reasonable  opinion  of its  counsel,  to  consummate  the  transactions
contemplated by this Agreement.

                                       12
<PAGE>

(f) PPI  acknowledges  that at the  Closing  MKRO will  transfer to Juan Ledo or
designee,  all assets  subject to  liabilities  and/or all stock of  Information
Management  Systems,  Inc.,  its  wholly  owned  subsidiary,   in  exchange  for
cancellation of 4,445,000 shares of common stock of MKRO standing in his name.

Section 5.2 CONDUCT BY MKRO PRIOR TO CLOSING. Between the date of this Agreement
and the  Closing  Date,  MKRO shall use its best  efforts to fulfill in a timely
manner all objectives and conditions to permit  consummation of the transactions
as  contemplated  by this  Agreement  and execute and deliver to PPI any and all
documents necessary, in the reasonable opinion of its counsel, to consummate the
transactions contemplated by this Agreement.

6.       CONDITIONS PRECEDENT TO OBLIGATIONS OF MKRO

The  obligations  of MKRO under this  Agreement  are, at its option,  subject to
satisfaction of the following conditions at or prior to the Closing:

Section 6.1  REPRESENTATIONS OF PPI. The  representations  and warranties of PPI
set forth in this Agreement  shal be true and complete in all material  respects
on and as of the  Closing to the same  extent and with the same force and effect
as if made on such date,  except as  expressly  provided to the contrary in this
Agreement.

Section 6.2  CONSENTS.  All  necessary  approvals  or  consents  shall have been
obtained  from any and all federal  departments  and agencies and from all other
commissions,  boards,  agencies and from any other person,  firm or entity whose
approval  or  consent  is  necessary  to the  consummation  of the  transactions
contemplated by this Agreement.

Section 6.3  PERFORMANCE BY PPI. PPI shall have duly performed all  obligations,
covenants and  agreements  undertaken by them herein and complied with all terms
and  conditions  applicable to them  hereunder to be performed and complied with
prior to the Closing.

Section 6.4 DOCUMENTS TO BE DELIVERED TO MKRO. MKRO shall have received:

(a) A certificate,  dated as of the Closing and executed by PPI certifying as to
the fulfillment of the matters contained in Sections 6.1, 6.2 and 6.3;

(b)  True  and  complete  copy  of the  certificates  of  incorporation  of PPI,
certified  by the  Secretary  of State of  Nevada,  and of the  by-laws  of PPI,
together with all amendments thereto, certified by the Secretary of PPI;

(c) Good standing  certificate  for PPI,  certified by the Secretary of State of
Nevada;

(d)  Certificates  representing  5,000,000 of the PPI Shares,  duly endorsed for
transfer,  and PPI shall  have  received  the MKRO  Shares,  duly  endorsed  for
transfer. All such shares shall be subject to Rule 144 legend.

(e) The Employment  Agreement  duly executed by the employees  listed on, in the
form of Schedule 2.6 hereof.

Section 6.5 SUITS. No suit,  action or other proceeding shall be a threatened or
pending  before  any court or  governmental  agency in which it will be or it is
sought  to  restrain  or  prohibit  or to  obtain  damages  or other  relief  in
connection  with  this  Agreement  or  the   consummation  of  the  transactions
contemplated  by this  Agreement or which is likely to materially  and adversely
affect the financial condition, results of operations,  business or prospects of
PPI.

                                       13
<PAGE>

7.       CONDITIONS PRECEDENT TO OBLIGATIONS OF PPI

The  obligations  of PPI under this  Agreement  are, at its  option,  subject to
satisfaction of the following conditions at or prior to the initial Closing:

Section 7.1 REPRESENTATIONS  AND WARRANTIES.  The representations and warranties
of MKRO set forth in this  Agreement  shall be true and complete in all material
respects on and as of the Closing to the same extent and with the same force and
effect  as if  made  on  such  date,  except  as  affected  by the  transactions
contemplated by this Agreement.

Section 7.2  CONSENTS.  All  necessary  approvals  or  consents  shall have been
obtained  from any and all federal  departments  and agencies and from all other
commissions,  boards,  agencies and from any other person,  firm or entity whose
approval  or  consent  is  necessary  to the  consummation  of the  transactions
contemplated by this Agreement.

Section 7.3 PERFORMANCE BY MKRO. MKRO shall have duly performed all obligations,
covenants and agreements undertaken by it herein and complied with all the terms
and  conditions  applcable to them  hereunder  to be performed or complied  with
prior to the Closing.

Section 7.4 DOCUMENTS TO BE DELIVERED TO PPI. PPI shall have received:

(a) A certificate,  dated as of the Closing, and executed by an officer of MKRO,
certifying as to the  fulfillment of the matters  contained in Sections 7.1, 7.2
and 7.3;

(b) Certificates  representing the MKRO Shares, duly endorsed for transfer,  and
MKRO  shall  have  received  5,000,000  of the PPI  Shares,  duly  endorsed  for
transfer.

(c) True and  complete  copies  of the  certificate  of  incorporation  of MKRO,
certified  by the  Secretary  of  State  of Utah,  and of the  by-laws  of MKRO,
together with all amendments thereto, certified by the Secretary of MKRO;

(d) Good standing  certificate for MKRO,  certified by the Secretary of State of
the domicile of each entity; and

(e) True and correct copies of Minutes of the Board of Directors authorizing the
officers of MKRO to consummate the transaction.

Section 7.5 SUITS. No suit,  action or other  proceeding  shall be threatened or
pending  before  any court or  governmental  agency in which it will be or it is
sought  to  restrain  or  prohibit  or to  obtain  damages  or other  relief  in
connection  with  this  Agreement  or  the   consummation  of  the  transactions
contemplated by this Agreement.


                                       14
<PAGE>

8.       SURVIVAL OF REPRESENTATIONS AND WARRANTIES AND INDEMNIFICATION

Section 8.1 SURVIVAL OF  REPRESENTATIONS  AND  WARRANTIES.  Notwithstanding  the
closing of the transactions contemplated by this Agreement, or any investigation
made by or on behalf of PPI or MKRO, the  representations  and warranties of PPI
or MKRO  contained in this  Agreement or in any  certificate,  schedule,  chart,
list, letter,  compilation or other document  delivered  pursuant hereto,  shall
survive the Closing for a period of one (1) year; provided,  however, that as to
any breach of, or  misstatement  in, any such  representation  or warranty as to
which one party has given notice to the other on or prior to the  expiration  of
such one (1) year period, the same shall continue to survive beyond said period,
but only as to the matters contained in such notice.

Section 8.2 PPI'S  INDEMNIFICATION.  PPI  covenants  and agrees to indemnify and
save harmless MKRO and its  directors,  officers,  employees and agents from any
and all costs,  expenses,  losses,  damages and liabilities incurred or suffered
directly or directly by any of them (including  reasonable legal fees and costs)
proximately resulting from or attributable to the breach of, or misstatement in,
any one or more of the  representations or warranties of PPI made in or pursuant
to this Agreement.

Section 8.3 MKRO'S  INDEMNIFICATION.  MKRO covenants and agrees to indemnify and
save harmless PPI and its directors, officers, employees and agents from any and
all costs, expenses, losses, damages and liabilities incurred or suffered by any
of them (including  reasonable legal fees and costs) proximately  resulting from
or  attributable  to the breach of, or  misstatement  in, any one or more of the
representations or warranties of MKRO made in or pursuant to this Agreement.

Section  8.4 DEFENSE  AGAINST  ASSERTED  CLAIMS.  If any claim or  assertion  of
liability  is made or  asserted  by a third  party  against a party  indemnified
pursuant to this  Section 8  ("Indemnified  Party")  based on any  liability  or
absence of right which, if established,  would constitute a matter for which the
Indemnified Party would be entitled to  indemnification  by another party hereto
("the   Indemnifying   Party")  the  Indemnified  Party  shall  with  reasonable
promptness  give to the  Indemnifying  Party  written  notice  of the  claim  or
asserting of liability  and request the  Indemnifying  Party to defend the same.
Failure to so notify the  Indemnifying  Party shall not relieve the Indemnifying
Party  of  any  liability  which  the  Indemnifying  Party  might  have  to  the
Indemnified  Party unless such failure  materially  prejudices the  Indemnifying
Party's position.  The Indemnifying Party shall have the right to defend against
such liability or assertion,  in which event the  Indemnifying  Party shall give
written  notice to the  Indemnified  Party of the  acceptance of defense of such
claim and the  identity  of  counsel  selected  by the  Indemnifying  Party with
respect to such matters.  The Indemnified Party shall be entitled to participate
with the  Indemnifying  Party in such  defense and also shall be entitled at its
option to  employ  separate  counsel  for such  defense  at the  expense  of the
Indemnified  Party.  In the event the  Indemnifying  Party  does not  accept the
defense of the matter as  provided  above or in the event that the  Indemnifying
Party or its counsel fails to use reasonable  care in maintaining  such defense,
the Indemnified  Party shall have the full right at its option to defend against
the liability or assertion and to employ counsel for such defense at the expense
of the Indemnifying  Party. All parties hereto will cooperate with each other in
the  defense  of any such  action  and the  relevant  records  of each  shall be
available to the others with respect to such defense.

9.       ASSIGNMENT, THIRD PARTIES, BINDING EFFECT

The rights under this Agreement shall not be assignable nor the duties delegable
by any party  without the  written  consent of all  parties  hereto  having been
obtained thereto.  Nothing contained in this Agreement,  express or implied,  is
intended to confer upon any person or entity, other than the parties hereto, and
their successors in interest,  any rights or remedies under or by reason of this
Agreement unless so stated expressly to the Contrary. All covenants, agreements,
representations, and warranties of the parties contained herein shall be binding
upon and inure to the  benefit of MKRO and PPI and their  respective  successors
and permitted assigns.

                                       15
<PAGE>

10.      ABANDONMENT

In the event the transactions contemplated hereby are terminated or abandoned by
mutual agreement or the parties hereto,  there shall be no liability on the part
of any of the parties by reason of such termination or abandonment.

11.      NOTICES

All notices,  requests,  demands and other communications  hereunder shall be in
writing and shall be deemed to have been duly given when personally delivered or
deposited in the United States mail,  certified or  registered,  return  receipt
requested,  postage prepaid, addressed to the parties at the following addresses
(or at such  other  address  as shall be given in  writing  by any  party to the
other) as follows:

           To MKRO:          Attn:  SAM J BOYER
                                    --------------------
                             Micronetics Inc.
                            14148 Magnolia Boulevard
                         Sherman Oaks, California 91423
                             Telephone: 818.784.6890     Facsimile: 818.784.6552

           With a copy to:   John Holt Smith, Esq.
                           Inman Steinberg Nye & Stone
                          1925 Century Park East #1600
                          Los Angeles, California 90067
                             Telephone: 310.274.7111    Facsimile: 310.274.8889

           To PPI:           Attn: ____________________
                           Praxis Pharmaceuticals Inc.
                              Northwestern Building
                            314-1008 Homer Boulevard
                             Vancouver, B.C. 6VB 2X1
                             Telephone:  604.718.6833    Facsimile: 604.718.6828

           With a copy to:   Lori Ann Fujioka, Esq.
                             Dill Dill Carr Stonbraker & Hutchings, P.C.
                             455 Sherman Street, Suite 300
                             Denver, Colorado 80203
                             Telephone: 303.777.3737   Facsimile: 303.777.3823

12.      REMEDIES NOT EXCLUSIVE

No remedy conferred by any of the provisions of this Agreement is intended to be
exclusive of any other remedy, and each and every remedy shall be cumulative and
shall be in  addition  to  every  remedy  given  hereunder  or now or  hereafter
existing,  at law or in equity by statute or otherwise.  The election of any one
or more  remedies by MKRO or PPI shall not  constitute  a waiver of the right to
pursue other available remedies.

13.      COUNTERPARTS

This Agreement may be executed in one or more counterparts,  each of which shall
be deemed to be an original but all of which together  shall  constitute one and
the same instrument.


                                       16
<PAGE>

14.      CAPTIONS AND SECTION HEADINGS

Captions and section headings used herein are for convenience only and are not a
part of this Agreement and shall not be used in construing it.

15.      WAIVERS

Any failure by any of the parties hereto to comply with all of the  obligations,
agreements  or  conditions  set forth herein may be waived by the other party or
parties,  provided, however that any such waiver shall not be deemed a waiver of
any other obligation, agreement or condition contained herein.

16.      ENTIRE AGREEMENT

This Agreement  constitutes the entire agreement between the parties.  There are
not  and  shall  not  be any  verbal  statements,  representations,  warranties,
undertakings  or agreements  between the parties,  and this Agreement may not be
amended or modified in any respect except by a written  instrument signed by the
parties hereto.

17.      APPLICABLE LAW

This  Agreement  shall be governed and construed in accordance  with the laws of
the State of California.

IN WITNESS WHEREOF, the parties have duly executed the Agreement as of the dated
first above written.

                                          MICRONETICS INC.

                                          By     /S/JUAN G. LEDO
                                          Name     JUAN G. LEDO
                                          Title         PRESIDENT

                                          PRAXIS PHARMACEUTICALS INC.

                                          By
                                          Name
                                          Title






                                       17
<PAGE>







                                   EXHIBIT 3.1

               ARTICLES OF INCORPORATION, AS AMENDED AND RESTATED


<PAGE>


              State of Utah                                            Co#096095
          Department of Commerce
Division of Corporations and Commerical Code

I hereby certify that the foregoing has been filed
and approved on the 8th day of Nov 1999
in the office of this Division and hereby issue
this Certificate thereof

Examiner  /s/Unknown  Date 11/18/99

                                                       UTAH DIV OF
                                                  CORPORATIONS AND UCC

                                                  '99 NOV -8 AM : 51


                      ARTICLES OF AMENDMENT AND RESTATEMENT
                                       OF
                           PRAXIS PHARMACEUTICALS INC.

         The undersigned,  being the Secretary of Praxis  Pharmaceuticals Inc. a
Utah corporation  (hereinafter  referred to as the  "Corporation"),  having been
authorized  to execute  these  Articles of  Amendment  and  Restatement,  hereby
certifies to the Division of Corporations and Commercial Code of Utah that:

         FIRST:  The  Corporation  desires to amend and restate its  Articles of
Incorporation as currently in effect as hereinafter provided.

         SECOND: The provisions set forth in these Amended and Restated Articles
of  Incorporation  supersede  the  original  Articles of  Incorporation  and all
amendments  thereto.  These  Amended  and  Restated  Articles  of  Incorporation
correctly set forth the provisions of the Articles of Incorporation,  as amended
to the date hereof.

         THIRD:   The  Board  of   Directors   duly  adopted  and  declared  the
advisability of the Amended and Restated Articles of Incorporation.

         FOURTH:  Shareholders  of  the  Corporation  holding  6,211,503  of the
11,322,209  outstanding  shares  (54.86%)  of  the  Corporation's  common  stock
approved  and  adopted the  amendments  contained  in the  Amended and  Restated
Articles of  Incorporation  at a shareholders'  meeting duly noticed and held on
August 30, 1999. The number of votes cast for the amendments were sufficient for
approval. There are no other classes of capital stock of the Corporation.

         FIFTH:   None   of   the   amendments   provides   for   an   exchange,
reclassification, or cancellation of issued shares.

         SIXTH: The Articles of Incorporation of the Corporation, as amended and
restated, are set forth on Exhibit A attached hereto.

                                                  /S/ DAVID STADNYK
                                                  David Stadnyk, Secretary

                                 ACKNOWLEDGMENT

State/Province of British Columbia
County/City of Vancouver

On September 20, 1999,  personally  appeared  before me, a Notary Public,  David
Stadnyk, who acknowledged that he executed the above instrument.


(Notary Stamp or Seal)                            /S/ DAVID J. COWAN
                                                  Notary Public

                                                      David J. Cowan
                                                   Barrister & Solicitor
                                               800 o 885 West Georgia Street
                                                  Vancouver, B.C. V6C 3H1


<PAGE>



                                    Exhibit A

                 AMENDED AND RESTATED ARTICLES OF INCORPORATION
                                       OF
                           PRAXIS PHARMACEUTICALS INC.


                                    ARTICLE I
                                      NAME

         The name of the corporation is Praxis Pharmaceuticals Inc.

                                   ARTICLE II
                                    DURATION

         The duration of this corporation is perpetual.

                                   ARTICLE III
                               PURPOSES AND POWERS

         The purpose or purposes for which this  corporation  is organized is to
engage in any lawful act or activity  for which  corporations  may be  organized
under the Utah Business Corporation Act.

                                   ARTICLE IV
                            AUTHORIZED CAPITAL STOCK

         SHARES.  The  amount  of  total  authorized  capital  stock  which  the
Corporation  shall have authority to issue is 50,000,000 shares of common stock,
each with $0.001 par value, and 10,000,000  shares of preferred stock, each with
$0.001 par value.

         COMMON  STOCK.  After the  requirements  with  respect to  preferential
dividends on the  preferred  stock,  if any,  shall have been met, and after the
Corporation shall have complied with all the requirements,  if any, with respect
to the  setting  aside  of sums as  sinking  funds  or  redemption  or  purchase
accounts,  then,  and not  otherwise,  the holders of the common  stock shall be
entitled to receive such  dividends as may be declared  from time to time by the
Board of Directors of the Corporation.

         After  distribution in full of the preferential  amount,  if any, to be
distributed  to the holders of the preferred  stock in the event of voluntary or
involuntary  liquidation,  distribution,  or sale  of  assets,  dissolution,  or
winding-up of the Corporation, the holders of the common stock shall be entitled
to  receive  all of  the  remaining  assets  of the  Corporation,  tangible  and
intangible, of whatever kind available for distribution to shareholders, ratably
in  proportion  to the  number  of  shares  of the  common  stock  held  by them
respectively.


                                       A-1

<PAGE>



         Except as may  otherwise be required by law,  each holder of the common
stock  shall have one vote in respect of each share of the common  stock held by
such holder on all matters voted upon by the shareholders.

         PREFERRED  STOCK.  To the fullest  extent  permitted by the laws of the
State of Utah  (currently  set forth in Section  16-10a-602 of the Utah Business
Corporation  Act),  as the  same now  exists  or may  hereafter  be  amended  or
supplemented,  the Board of Directors may fix and  determine  the  designations,
rights,  preferences  or other  variations  of each class or series  within each
class of capital stock of the Corporation.

                                    ARTICLE V
                                    DIRECTORS

         The Directors are hereby  granted the authority to do any act on behalf
of the  Corporation  as may be  allowed by law.  Any action  taken in good faith
shall be  deemed  appropriate  and in each  instance  where  the  Utah  Business
Corporation  Act provides that the Directors may act in certain  instances where
the Articles of Incorporation so authorize, such action by the Directors,  shall
be deemed to exist in these Articles and the authority granted by said law shall
be imputed hereto without the same specifically having been enumerated herein.

         The  Board  of  Directors  may  consist  of from  one  (1) to nine  (9)
directors,  as  determined,  from time to time,  by the then  existing  Board of
Directors.

                                   ARTICLE VI
                                CUMULATIVE VOTING

         Cumulative voting shall not be permitted in the election of directors.

                                   ARTICLE VII
                        LIMITATION ON DIRECTOR LIABILITY

         A director of the  Corporation  shall not be  personally  liable to the
Corporation or to its  shareholders for monetary damages for breach of fiduciary
duty as a director;  except that this provision shall not eliminate or limit the
liability of a director to the Corporation or to its  shareholders  for monetary
damages otherwise existing for (i) the amount of a financial benefit received by
a director to which he is not entitled;  (ii) an intentional  infliction of harm
on the Corporation or its shareholders;  (iii) a violation of Section 16-10a-842
of the Utah  Business  Corporation  Act;  or (iv) an  intentional  violation  of
criminal  law. If the Utah  Business  Corporation  Act is  hereafter  amended to
eliminate or limit further the liability of a director, then, in addition to the
elimination and limitation of liability provided by the preceding sentence,  the
liability of each director  shall be eliminated or limited to the fullest extent
permitted  by the Utah  Business  Corporation  Act as so amended.  Any repeal or
modification of this Article shall not adversely  affect any right or protection
of a director of the Corporation under this Article, as in effect immediately

                                       A-2

<PAGE>


prior to such repeal or  modification,  with respect to any liability that would
have accrued, but for this Article, prior to such repeal or modification.

                                  ARTICLE VIII
                                 INDEMNIFICATION

         The Corporation  shall  indemnify,  to the fullest extent  permitted by
applicable  law in effect  from time to time,  any  person,  and the  estate and
personal  representative  of any such person,  against all liability and expense
(including  attorneys'  fees) incurred by reason of the fact that he is or was a
director  or officer  of the  Corporation  or,  while  serving as a director  or
officer  of  the  Corporation,  he is or  was  serving  at  the  request  of the
Corporation as a director,  officer, partner, trustee,  employee,  fiduciary, or
agent of,  or in any  similar  managerial  or  fiduciary  position  of,  another
domestic or foreign  corporation or other individual or entity or of an employee
benefit plan. The Corporation  shall also indemnify any person who is serving or
has served the Corporation as director, officer, employee,  fiduciary, or agent,
and that person's estate and personal  representative,  to the extent and in the
manner  provided in any bylaw,  resolution  of the  shareholders  or  directors,
contract, or otherwise, so long as such provision is legally permissible.

                                   ARTICLE IX
                                  SHAREHOLDERS

         PREEMPTIVE  RIGHTS.  Shareholders  shall not have pre-emptive rights to
acquire unissued shares of the stock of this Corporation.

         NONASSESSABLE  STOCK.  The  capital  stock,  after  the  amount  of the
subscription  price has been paid in, shall not be subject to  assessment to pay
the debts of said Corporation,  whether issued for money, services,  property or
otherwise.  The private property of the stockholders shall not be subject to the
payment of corporate debts to any extent whatever.

         ACTION WITHOUT MEETING.  Subject to the provisions of the Utah Business
Corporation  Act, now contained in Section  16-10a-704,  any action which may be
taken at any annual or special  meeting of  shareholders  may be taken without a
meeting and without  prior notice,  if one or more consents in writing,  setting
forth the action so taken,  shall be signed by the holders of outstanding shares
having not less than the  minimum  number of votes that  would be  necessary  to
authorize  or take the action at a meeting at which all shares  entitled to vote
thereon were present and voted.

                                    ARTICLE X
                           REGISTERED AGENT AND OFFICE

         The street address of the current  registered office of the Corporation
is 50 West  Broadway,  Salt Lake City,  Utah 84101,  and the name of the initial
registered agent at that address is CT Corporation System.


                                       A-3

<PAGE>







                                   EXHIBIT 3.2

                                     BYLAWS


<PAGE>

                                   EXHIBIT "A"
                                     BY-LAWS

                                       OF

                                     WIZARD

                               ARTICLE I. OFFICES

                  The principal office of the corporation in the State of Utah
shall be located in Salt Lake City, Utah. The corporation may have such other
offices, either within or without the State of Utah, as the Board of Directors
may designate or as the business of the Corporation may require from time to
time.

                  The registered office of the Corporation required by the Utah
Business Corporation Act to be maintained in the State of Utah may be, but need
not be, identical with the principal office in the State of Utah, and the
address of the registered office may be changed from time to time by the Board
of Directors.

                            ARTICLE II. SHAREHOLDERS

                  SECTION 1. ANNUAL MEETING. The annual meeting of the
shareholders shall be held on such date and at such time as the Board of
Directors shall determine which is within 90 days after the end of its fiscal
year, beginning with the year next following the year of its incorporation, for
the purpose of electing Directors and for the transaction of such other business
as may come before the meeting. The day fixed for the annual meeting shall not
be a legal holiday in the State of Utah. If the election of Directors shall not
be held on the day designated herein or any annual meeting of the shareholders,
or at any adjournment thereof, the Board of Directors shall cause the election
to be held at a special meeting of the shareholders as soon thereafter as
conveniently may be.

                  SECTION 2. SPECIAL MEETINGS. Special meetings of the
shareholders, for any purpose or purposes, unless otherwise prescribed by
statute, may be called by the President or by the Board of Directors, and shall
be called by the President at the request of the holders of not less than
one-tenth of all outstanding shares of the Corporation entitled to vote at the
meeting.



<PAGE>



                  SECTION 3. PLACE OF MEETING. The Board of Directors may
designate any place, either within or without the State of Utah, as the place of
meeting for any annual meeting or for any special meeting called by the Board of
Directors. A waiver of notice signed by all shareholders entitled to vote at a
meeting may designate any place, either within or without the State of Utah, as
the place for the holding of such meeting. If no designation is made, or if a
special meeting be otherwise called, the place of meeting shall be the principal
office of the corporation in the State of Utah.

                  SECTION 4. NOTICE OF MEETING. Written notice stating the
place, day and hour of the meeting and, in case of a special meeting, the
purpose or purposes for which the meeting is called, shall, unless otherwise
prescribed by statute, be delivered not less than ten nor more than fifty days
before the date of the meeting, either personally or by mail, by or at the
direction of the President, or the Secretary, or the persons calling the
meeting, to each shareholder of record entitled to vote at such meeting. If
mailed, such notice shall be deemed to be delivered when deposited in the United
States mail, addressed to the shareholder at his address as it appears on the
stock transfer books of the corporation, with postage thereon prepaid.

                  SECTION 5. CLOSING OF TRANSFER BOOKS OR FIXING OF RECORD DATE.
For the purpose of determining shareholders entitled to notice of or to vote at
any meeting of shareholders or any adjournment thereof, or shareholders entitled
to receive payment of any dividend, or in order to make a determination of
shareholders for any other proper purpose, the Board of Directors of the
corporation may provide that the stock transfer books shall be closed for a
stated period but not to exceed, in any case, fifty days. If the stock transfer
books shall be closed for the purpose of determining shareholders entitled to
notice of or to vote at a meeting of shareholders, such books shall be closed
for at least ten days immediately preceding such meeting. In lieu of closing the
stock transfer books, the Board of Directors may fix in advance a date as the
record date for any such determination of shareholders, such date in any case to
be not more than fifty days and, in case of a meeting of shareholders, not less
than ten days prior to the date on which the particular action, requiring such
determination of shareholders, is to be taken. If the stock

                                       -2-



<PAGE>



transfer books are not closed and no record date is fixed for the determination
of shareholders entitled to notice of or to vote at a meeting of shareholders,
or shareholders entitled to receive payment of a dividend, the date on which
notice of the meeting is mailed or the date on which the resolution of the Board
of Directors declaring such dividend is adopted, as the case may be, shall be
the record date for such determination of shareholders. When a determination of
shareholders entitled to vote at any meeting of shareholders has been made as
provided in this section, such determination shall apply to any adjournment
thereof.

                  SECTION 6. VOTING LISTS. The officer or agent having charge of
the stock transfer books for shares of the corporation shall make a complete
list of the shareholders entitled to vote at each meeting of shareholders or any
adjournment thereof, arranged in alphabetical order, with the address of and the
number of shares held by each. Such list shall be produced and kept open at the
time and place of the meeting and shall be subject to the inspection of any
shareholder during the whole time of the meeting for the purposes thereof.

                  SECTION 7. QUORUM. A majority of the outstanding shares of the
corporation entitled to vote, represented in person or by proxy, shall
constitute a quorum at a meeting of shareholders. If less than a majority of the
outstanding shares are represented at a meeting, a majority of the shares so
represented may adjourn the meeting from time to time without further notice. At
such adjourned meeting at which a quorum shall be present or represented, any
business may be transacted which might have been transacted at the meeting as
originally noticed. The shareholders present at a duly organized meeting may
continue to transact business until adjournment, notwithstanding the withdrawal
of enough shareholders to leave less than a quorum.

                  SECTION 8. PROXIES. At all meetings of shareholders, a
shareholder may vote in person or by proxy exectued in writing by the
shareholder or by his duly authorized attorney in fact. Such proxy shall be
filed with the secretary of the corporation before or at the time of the
meeting. No proxy shall be valid after eleven months from the date of its
execution, unless otherwise provided in the proxy.

                  SECTION 9. VOTING OF SHARES. Subject to the provisions of the
Articles of Incorporation, each outstanding share entitled to vote shall be
entitled to one vote upon each matter submitted

                                       -3-



<PAGE>



to a vote at a meeting of shareholders.

                  SECTION 10. VOTING OF SHARES BY CERTAIN HOLDERS. Shares
outstanding in the name of another corporation may be voted by such officer,
agent or proxy as the by-laws of such corporation may prescribe, or, in the
absence of such provision, as the board of directors of such corporation may
determine.

                  Shares held by an administrator, executor, guardian or
conservator may be voted by him, either in person or by proxy, without a
transfer of such shares into his name. Shares standing in the name of a trustee
may be voted by him, either in person or by proxy, but no trustee shall be
entitled to vote shares held by him without a transfer of such shares into his
name.

                  Shares standing in the name of a receiver may be voted by such
receiver, and shares held by or under the control of a receiver may be voted by
such receiver without the transfer thereof into his name if authority so to do
be contained in an appropriate order of the court by which such receiver was
appointed.

                  A shareholder whose shares are pledged shall be entitled to
vote such shares until the shares have been transferred into the name of the
pledgee, and thereafter the pledgee shall be entitled to vote the shares so
transferred.

                  Neither shares of its own stock held by the corporation, nor
those held by another corporation if a majority of the shares entitled to vote
for the election of directors of such other corporation are held by the
corporation, shall be voted at any meeting or counted in determining the total
number of outstanding shares at any given time for purposes of any meeting.

                  SECTION 11. INFORMAL ACTION BY SHAREHOLDERS. Any action
required to be taken at a meeting of the shareholders, or any action which may
be taken at a meeting of the shareholders, may be taken without a meeting if a
consent in writing, setting forth the action so taken, shall be signed by all of
the shareholders entitled to vote with respect to the subject matter thereof.

                         ARTICLE III. BOARD OF DIRECTORS

                  SECTION 1.   GENERAL POWERS.  The business and affairs of the
corporation shall be managed by its Board of Directors.


                  SECTION 2.   NUMBER, TENURE AND QUALIFICATIONS.  The number of
directors of the corporation shall be not less than three (3) nor more than nine
(9) as determined, from time to time, by the Board of Directors.  The number of
original directors shall be as set forth in the Articles of Incorporation.  Each
Director shall

                                       -4-
<PAGE>

hold office until the next annual meeting of shareholders and until his
successor shall have been elected and qualified. Directors need not be residents
of the State of Utah or shareholders of the corporation.

                  SECTION 3. REGULAR MEETINGS. A regular meeting of the Board of
Directors shall be held without other notice than this by-law immediately after,
and at the same place as, the annual meeting of shareholders. The Board of
Directors may provide, by resolution, the time and place, either within or
without the State of Utah, for the holding of additional regular meetings
without other notice than such resolution.

                  SECTION 4. SPECIAL MEETINGS. Special meetings of the Board of
Directors may be called by or at the request of the President or any two
Directors. The person or persons authorized to call special meetings of the
Board of Directors may fix any place, either within or without the State of
Utah, as the place for holding any special meeting of the Board of Directors
called by them.

                  SECTION 5. NOTICE. Notice of any special meeting shall be
given at least two days previously thereto by written notice delivered
personally or mailed to each Director at his business address, or by telegram.
If mailed, such notice shall be deemed to be delivered when deposited in the
United States mail, so addressed, with postage thereon prepaid. If notice be
given by telegram such notice shall be deemed to be delivered when the telegram
is delivered to the telegraph company. Any Director may waive notice of any
meeting. The attendance of a Director at a meeting shall constitute a waiver of
notice of such meeting, except where a Director attends a meeting for the
express purpose of objecting to the transaction of any business because the
meeting is not lawfully called or convened. Neither the business to be
transacted at, nor the purpose of, any regular or special meeting of the Board
of Directors need be specified in the notice or waiver of notice of such
meeting.

                  SECTION 6. QUORUM. A majority of the number of Directors fixed
by Section 2 of this Article III shall constitute a quorum for the transaction
of business at any meeting of the Board of Directors, but if less than such
majority is present at a meeting, a majority of the Directors present may
adjourn the meeting from time to time without further notice.

                  SECTION 7.   MANNER OF ACTING.  The act of the majority of the
Directors present at a meeting at which a quorum is present shall be the act of
the Board of Directors.  Any action which may

                                       -5-

<PAGE>

be taken at a meeting of the directors may be taken without a meeting if a
consent in writing, setting forth the action so taken, shall be signed by all of
the directors.

                  SECTION 8. VACANCIES. Any vacancy occurring in the Board of
Directors may be filled by the affirmative vote of a majority of the remaining
Directors though less than a quorum of the Board of Directors. A Director
elected to fill a vacancy shall be elected for the unexpired term of his
predecessor in office. Any directorship to be filled by reason of an increase in
the number of Directors may be filled by election by the Board of Directors for
a term of office continuing only until the next election of Directors by the
shareholders.

                  SECTION 9. COMPENSATION. By resolution of the Board of
Directors, each Director may be paid his expenses, if any, of attendance at each
meeting of the Board of Directors, and may be paid a stated salary as director
or a fixed sum for attendance at each meeting of the Board of Directors or both.
No such payment shall preclude any Director from serving the corporation in any
other capacity and receiving compensation therefor.

                  SECTION 10. PRESUMPTION OF ASSENT. A Director of the
corporation who is present at a meeting of the Board of Directors at which
action on any corporate matter is taken shall be presumed to have assented to
the action taken unless his dissent shall be entered in the minutes of the
meeting or unless he shall file his written dissent to such action with the
person acting as the secretary of the meeting before the adjournment thereof or
shall forward such dissent by registered mail to the Secretary of the
corporation immediately after the adjournment of the meeting. Such right to
dissent shall not apply to a Director who voted in favor of such action.

                              ARTICLE IV. OFFICERS.

                  SECTION 1. NUMBER. The officers of the corporation shall be a
President, one or more Vice-Presidents (the number thereof to be determined by
the Board of Directors), a Secretary, and a Treasurer, each of whom shall be
elected by the Board of Directors. Such other officers and assistant officers as
may be deemed necessary may be elected or appointed by the Board of Directors.
Any two or more offices may be held by the same person, except the offices of
President and Secretary.

                  SECTION 2. ELECTION AND TERM OF OFFICE. The officers of the
corporation to be elected by the Board of Directors shall be elected annually by
the Board of Directors at the first meting of the Board of Directors held after
each annual meeting of the shareholders. If the election of officers shall not
be held

                                       -6-

<PAGE>

at such meeting, such election shall be held as soon thereafter as conveniently
may be. Each officer shall hold office until his successor shall have been duly
elected and shall have qualified or until his death or until he shall resign or
shall have been removed in the manner hereinafter provided.

                  SECTION 3. REMOVAL. Any officer or agent may be removed by the
Board of Directors whenever in its judgment, the best interests of the
corporation will be served thereby, but such removal shall be without prejudice
to the contract rights, if any, of the person so removed. Election or
appointment of an officer or agent shall not of itself create contract rights.

                  SECTION 4. VACANCIES. A vacancy in any office because of
death, resignation, removal, disqualification or otherwise, may be filled by the
Board of Directors for the unexpire portion of the term.

                  SECTION 5. PRESIDENT. The President shall be the principal
executive officer of the corporation and, subject to the control of the Board of
Directors, shall in general supervise and control all of the business and
affairs of the corporation. He shall, when present, preside at all meetings of
the shareholders and of the Board of Directors. He may sign, with the Secretary
or any other proper officer of the corporation thereunto authorized by the Board
of Directors, certificates for shares of the corporation, any deeds, mortgages,
bonds, contracts, or other instruments which the Board of Directors has
authorized to be executed, except in cases where the signing and execution
thereof shall be expressly delegated by the Board of Directors or by these
ByLaws to some other officer or agent of the corporation, or shall be required
by law to be otherwise signed or executed; and in general shall perform all
duties as may be prescribed by the Board of Directors from time to time.

                  SECTION 6. THE VICE-PRESIDENTS. In the absence of the
President or in the event of his death, inability or refusal to act, the
Vice-President (or in the event there be more than one Vice-President, the
Vice-Presidents in the order designated at the time of their election, or in the
absence of any designation, then in the order of their election) shall perform
the duties of the President, and when so acting, shall have all the powers of
and be subject to all the restrictions upon the President. Any Vice-Presidnet
may sign, with the Secretary or an Assistant Secretary, certificates for shares
of the corporation; and shall perform such other duties as from time to time may
be assigned to him by the President or by the Board of Directors.

                                       -7-

<PAGE>

                  SECTION 7. THE SECRETARY. The Secretary shall: (a) keep the
minutes of the proceedings of the shareholders and of the Board of Directors in
one or more books provided for that purpose; (b) see that all notices are duly
given in accordance with the provisions of these By-Laws or as required by law;
(c) be custodian of the corporate records and of the seal of the corporation and
see that the seal of the corporation is affixed to all documents the execution
of which on behalf of the corporation under its seal is duly authorized; (d)
keep a register of the post office address of each shareholder; (e) sign with
the President, or a Vice-President, certificates for shares of the corporation,
the issuance of which shall have been authorized by resolution of the Board of
Directors; (f) have general charge of the stock transfer books of the
corporation; and (g) in general perform all duties incident to the office of
Secretary and such other duties as from time to time may be assigned to him by
the President or by the Board of Directors.

                  SECTION 8. THE TREASURER. The Treasurer shall: (a) have charge
and custody of and be responsible for all funds and securities of the
corporation; (b) receive and give receipts for moneys due and payable to the
corporation from any source whatsoever, and deposit all such moneys in the name
of the corporation in such banks, trust companies or other depositaries as shall
be selected in accordance with the provisions of Article V of these By-Laws; and
(c) in general perform all of the duties as from time to time may be assigned to
him by the President or by the Board of Directors. If required by the Board of
Directors, the Treasurer shall give a bond for the faithful discharge of his
duties in such sum and with such surety or sureties as the Board of Directors
shall determine.

                  SECTION 9. ASSISTANT SECRETARIES AND ASSISTANT TREASURERS. The
Assistant Secretaries, when authorized by the Board of Directors, may sign with
the President or a Vice-President certificates for shares of the corporation the
issuance of which shall have been authorized by a resolution of the Board of
Directors. The Assistant Treasurers shall respectively, if required by the Board
of Directors, give bonds for the faithful discharge of their duties in such sums
and with such sureties as the Board of Directors shall determine. The Assistant
Secretaries and Assistant Treasurers, in general, shall perform such duties as
shall be assigned to them by the Secretary or the Treasurer, respectively, or by
the President or the Board of Directors.

                  SECTION 10. SALARIES. The salaries of the officers shall be
fixed from time to time by the Board of Directors and no officer shall be
prevented from receiving such salary by reason of the fact that he is also a
Director of the corporation.

                                       -8-

<PAGE>

                ARTICLE V. CONTRACTS, LOANS, CHECKS AND DEPOSITS

                  SECTION 1. CONTRACTS. The Board of Directors may authorize any
officer or officers, agent or agents, to enter into any contract or execute and
deliver any instrument in the name of and on behalf of the corporation, and such
authority may be general or confined to specific instances.

                  SECTION 2. LOANS. No loans shall be contracted on behalf of
the corporation and no evidence of indebtedness shall be issued in its name
unless authorized by a resolution of the Board of Directors. Such authority may
be general or confined to specific instances.

                  SECTION 3. CHECKS, DRAFTS, ETC. All checks, drafts or other
orders for the payment of money, notes or other evidences of indebtedness issued
in the name of the corporation, shall be signed by such officer or officers,
agent or agents of the corporation and in such manner as shall from time to time
be determined by resolution of the Board of Directors.

                  SECTION 4. DEPOSITS. All funds of the corporation not
otherwise employed shall be deposited from time to time to the credit of the
corporation in such banks, trust companies or other depositaries as the Board of
Directors may select.

             ARTICLE VI. CERTIFICATES FOR SHARES AND THEIR TRANSFER

                  SECTION 1. CERTIFICATES FOR SHARES. Certificates representing
shares of the corporation shall be in such form as shall be determined by the
Board of Directors. Such certificates shall be signed by the President or a
Vice-President and by the Secretary or an Assistant Secretary and sealed with
the corporate seal or a facsimile thereof. The signatures of such officers upon
a certificate may be facsimiles if the certificate is countersigned by a
transfer agent, or registered by a registrar, other than the corporation itself
or one of its employees. All certificates for shares shall be consecutively
numbered or otherwise identified. The name and address of the person to whom the
shares represented thereby are issued, with the number of shares and date of
issue, shall be entered on the stock transfer books of the corporation. All
certificates surrendered to the corporation for transfer shall be cancelled and
no new certificate shall be issued until the former certificate for a like
number of shares shall have been; surrendered and cancelled, except that in case
of a lost, destroyed or mutilated certificate a new one may be issued therefor
upon such terms and indemnity to the corporation as the Board of Directors may
prescribe.

                  SECTION 2. TRANSFER OF SHARES. Transfer of shares of the
corporation shall be made only on the stock transfer books of the corporation by
the holder of record thereof or by his legal representative, who shall furnish
proper evidence of authority to transfer, or by his attorney thereunto
authorized by power of

                                       -9-



<PAGE>



attorney duly executed and filed with the Secretary of the Corporation, and on
surrender for cancellation of the certificate for such shares. The person in
whose name shares stand on the books of the Corporation shall be deemed by the
Corporation to be the owner thereof for all purposes.

                            ARTICLE VII. FISCAL YEAR

                  The fiscal year of the Corporation shall begin on the first
day of January and end on the thirty-first day of December in each year.

                             ARTICLE VIII. DIVIDENDS

                  The Board of Directors may, from time to time, declare and the
Corporation may pay dividends on its outstanding shares in the manner, and upon
the terms and conditions provided by law and its Articles of Incorporation.

                           ARTICLE IX. CORPORATE SEAL

                  The Board of Directors shall provide a corporate seal.

                           ARTICLE X. WAIVER OF NOTICE

                  Whenever notice is required to be given to any shareholder or
director of the Corporation under the provisions of these By-Laws or under the
provisions of the Articles of Incorporation or under the provisions of the Utah
Business Corporation Act, a waiver thereof in writing signed by the person or
persons entitled to such notice, whether before or after the time stated
therein, shall be deemed equivalent to the giving of such notice.

                             ARTICLE XI. AMENDMENTS

                  These By-Laws may be altered, amended or repealed and new
ByLaws may be adopted by the Board of Directors at any regular or special
meeting of the Board of Directors.

                 ARTICLE XII. PROCEDURE FOR CONDUCTING MEETINGS

                  All shareholder and director meetings shall be conducted in
accordance with the rules and procedures set forth in the most current edition
of ROBERTS' RULES OF ORDER.

                                                     ATTEST:

                                                     /S/  PAT M. BURKE
                                                     Secretary



<PAGE>






                                  EXHIBIT 10.1

                   RESEARCH, DEVELOPMENT AND LICENCE AGREEMENT
                           DATED MAY 11, 1999 BETWEEN
          PRAXIS PHARMACEUTICALS, INC. AND FAIRCHILD INTERNATIONAL INC.


<PAGE>



                   RESEARCH, DEVELOPMENT AND LICENCE AGREEMENT
                         DATED THE 11TH DAY OF MAY, 1999

BETWEEN:

                          PRAXIS PHARMACEUTICALS, INC.,
                     a body corporate incorporated pursuant
                        to the laws of the State of Utah,
                       one of the United States of America
                             and having an office at
                        ANUTECH Court, North Road, in the
                        City of Canberra, ACT, Australia
                                   ("Praxis")

                                     - and -

                 FAIRCHILD INTERNATIONAL INC., a body corporate
                      incorporated pursuant to the laws of
                    the Province of British Columbia, Canada
                             and having an office at
                          Suite 600, 595 Hornby Street,
                   City of Vancouver, British Columbia, Canada
                                  ("FAIRCHILD")


                  WHEREAS:



A. The Australian National University is the owner of certain patents related to
the invention entitled "Phosphosugar-based anti-inflammatory and/or
immunosuppressive drugs" and certain patent applications related to an invention
entitled "Novel phosphosugars and phosphosugar-containing compounds having
anti-inflammatory activity" which are described in more detail herein;

B.                ANUTECH PTY Ltd. ("Anutech"), the commercialization company of
                  the Australian National University, has entered into an
                  agreement as agent for and on behalf of the Australian
                  National University with Praxis pursuant to which Praxis has
                  been granted an exclusive licence for the use of the
                  inventions described above in specified areas of application;

C.       Praxis has and intends to continue to conduct research and development

<PAGE>

                                      -2-

related to the above described inventions;

D. Praxis wishes to obtain funding from FAIRCHILD to conduct research in the
area of arthritis and dermal wrinkles and related to the above inventions;

E. FAIRCHILD wishes to obtain an exclusive, world-wide licence to make, use and
sell products and processes developed by Praxis relating to arthritis and dermal
wrinkles;

                  NOW THEREFORE, in consideration of the mutual terms and
conditions contained herein, the parties hereto agree as follows:

                     PART I - DEFINITIONS AND INTERPRETATION

SECTION 1 - DEFINITIONS

                  In this Agreement, including this Section, the following
defined terms have the meanings indicated:

         (a)      "Anutech Licence Agreements" means the agreement entered into
                  between Anutech and Praxis dated 27th October, 1997, a copy of
                  which is attached hereto as Schedule "D";

         (b)      "Closing Date" means September 30th, 1999

         (c)      "Confidential Information" means confidential or proprietary
                  information, trade secrets, know-how and technical information
                  related to the inventions claimed pursuant to the Patents and
                  any other information disclosed in confidence by Praxis to
                  FAIRCHILD or by FAIRCHILD to Praxis;

         (d)      "Field of Use" means arthritis and dermal wrinkles;

         (e)      "Intellectual Property" means any and all methods, devices,
                  techniques, discoveries, inventions (whether or not
                  patentable), know-how, ideas,

<PAGE>

                                       -3-

                  processes, trade secrets and other proprietary information,
                  including any patent right, copyright, trade secret or similar
                  right;

         (f)      "Licensed Patent Applications" means:

                  (i)      the patent applications relating to the invention
                           entitled "Novel phosphosugars and
                           phosphosugar-containing compounds having
                           anti-inflammatory activity", including United State
                           Patent Application No. 08/953305, Australian
                           Application No. 41866/97 and any patent applications
                           filed now or in the future in any country which
                           disclose and claim the same inventions or the
                           priority of Australian Provisional Application PO
                           3098/96, filed October 18, 1996; and

                  (ii)     all patent applications related to the New
                           Intellectual Property;

         (g)      "Licensed Patents" means:

                  (i)      the patents described on Schedule "A" hereto;

                  (ii)     all patents issued out of the Patent Applications;

                  (iii)    any patents issued in any country disclosing and
                           claiming the same inventions as those claimed in the
                           patents referred to in clauses (i) and (ii) hereof;
                           and

                  (iv)     all divisions, re-issues, re-examinations,
                           continuations, renewals and extensions of the
                           foregoing;

         (h)      "Licensed Product" means any product the manufacture or use of
                  which is covered by a Valid Claim;

         (i)      "Licensed Technology" means:

                  (i)      the inventions disclosed and claimed in the Licensed
                           Patent Applications and Licensed Patents;

                  (ii)     any additional Intellectual Property related to the
                           inventions referred to in clause (i), their
                           description, use, or application; and

                  (iii)    all Confidential Information in any way related to
                           the inventions referred to in clause (i) hereof and
                           the Intellectual Property referred to in clause (ii)
                           hereof;

<PAGE>

                                       -4-
         (j) "Net Revenue" means all consideration received by FAIRCHILD:

                  (i)      for the sale or other disposition of Licensed
                           Products; and

                  (ii)     pursuant to the terms of any sublicences granted by
                           FAIRCHILD in accordance with Section 11(3);

                  less the following:

                           (A)      all costs incurred by FAIRCHILD in the
                                    development of Licensed Products, including,
                                    without limitation, payments made by
                                    FAIRCHILD to Praxis pursuant to Section 8,
                                    costs and expenses incurred by FAIRCHILD
                                    pursuant to Section 13 and expenses incurred
                                    by FAIRCHILD in connection with obtaining
                                    Regulatory Approvals, including those
                                    referred to in Section 17;

                           (B)      all costs of direct materials, labour and
                                    overhead expenses required in the
                                    manufacture and production of Licensed
                                    Products;

                           (C)      costs incurred by FAIRCHILD in connection
                                    with the marketing, selling and distribution
                                    of Licensed Products;

                           (D)      any tax or government charge (other than an
                                    income tax) levied on the sale,
                                    transportation or delivery of Licensed
                                    Product;

                           (E)      trade and quantity discounts or rebates
                                    actually allowed and taken; and

                           (F)      credits or allowances given or made for
                                    rejection or return of previously sold
                                    Licensed Products;


         (k)      "New Intellectual Property" means Intellectual Property that
                  is developed by Praxis during the conduct of the Research
                  Projects performed by Praxis in accordance with Section 8;

         (l)      "Regulatory Approval" means any approvals, licenses,
                  registrations or authorizations of any relevant authority
                  having jurisdiction necessary for the development, use,
                  importation, packaging, marketing, distribution, sale, storage
                  and transportation of the Licensed Products;

<PAGE>

                                       -5-
         (m)      "Research Projects" means the Research and Development
                  Projects relating to dermal wrinkles and arthritis conducted
                  in accordance with Section 8;

         (n)      "Shares" means shares in the capital stock of FAIRCHILD
                  described as Class A Common and having the rights set out on
                  Schedule "B" hereto;

         (o)      "Valid Claim" means a claim of any issued and unexpired
                  Licensed Patent which claim has not been held unenforceable,
                  unpatentable or invalid by a decision of a court or government
                  body of competent jurisdiction, unappealable or unappealed
                  within the time allowed for appeal, which has not been
                  rendered unenforceable through disclaimer or otherwise, and
                  which has not been lost through an interference proceeding or
                  by abandonment.


SECTION 2 - GOVERNING LAW AND JURISDICTION

                  This Agreement shall be governed by and interpreted in

accordance with the laws in force in the Province of British Columbia. The

parties hereby submit to the jurisdiction of the Courts of British Columbia.


SECTION 3 - CURRENCY

                  All monetary units, except as expressly stated otherwise in

this Agreement, are in United States dollars.


SECTION 4 - AFFILIATES

                  For the purpose of this Agreement, a company is an Affiliate
of a party if:

         (a)      the party owns or controls, directly or indirectly, 50% or
                  more of the voting stock of that company;

         (b)      the party owns or controls, directly or indirectly, sufficient
                  voting stock in that company to elect a majority of the
                  directors of that company;

<PAGE>
                                       -6-

         (c)      that company owns or controls, directly or indirectly, 50% or
                  more of the voting stock of the party;

         (d)      that company owns or controls, directly or indirectly,
                  sufficient voting stock in the party to elect a majority of
                  the directors of the party;

         (e)      an organization owns or controls, directly or indirectly, 50%
                  or more of the voting stock of the party and that company; or

         (f)      an organizations owns or controls, directly or indirectly,
                  sufficient voting stock in the party and the company to elect
                  a majority of the directors of the party and that company.


SECTION 5 - SCHEDULES

                  The following Schedules are incorporated into and form part of

this Agreement:

                           Schedule "A" - Patents
                           Schedule "B" - Share Rights
                           Schedule "C" - Research Projects
                           Schedule "D" - Anutech Licence


                      PART II - PURCHASE AND SALE OF SHARES

SECTION 6 - SUBSCRIPTION AND PURCHASE

(1) In consideration for the licensing rights to the Praxis Intellectual
Property, FAIRCHILD hereby agrees to transfer, on or before the Closing Date,
260,000 pre-split shares or 2.6 million post-split shares of Fairchild
International Inc. to Praxis, and guarantees that the Shares will be issued as
fully paid up and non-accessible Shares; that the Shares be allotted and that a
certificate for the Shares be issued to Praxis.

<PAGE>
                                      -7-

(2) Praxis shall certify as at the Closing Date that the following

representations and warranties are correct:

         (a)      Praxis is engaged primarily in the business of developing a
                  unique panel of natural carbohydrate based compounds and
                  exploiting commercial applications of such;

         (b)      there are no material lawsuits against Praxis, or its
                  directors or officers that are related to the business of
                  Praxis, nor, to the best of the knowledge of Praxis and its
                  directors and officers are any being contemplated;

         (c)      Praxis is current in all taxes owed, including payroll taxes,
                  and on all debts, accounts payable and leases;

         (d)      Praxis has provided copies of its most recent financial
                  statements to FAIRCHILD and the information contained in such
                  financial statements is complete and accurately reflects
                  Praxis' situation, financial and otherwise;

         (e)      a copy of every material executed lease, licence, partnership
                  or collaboration agreement (whether technical, marketing,
                  manufacturing or other) stockholder agreement, loan agreement,
                  employment agreement, purchase and sale agreement has been
                  provided to FAIRCHILD;

         (f)      a comprehensive listing and description of all Intellectual
                  Property in the name of Praxis or obtained by Praxis through
                  licensing has been provided to FAIRCHILD as have copies of
                  file wrappers for all Licensed Patent Applications and there
                  are no existing or potential patent disputes of which Praxis
                  is aware or for which Praxis has not provided full and
                  complete disclosure to FAIRCHILD;

         (g)      a complete and current listing of Praxis' capital structure
                  and the terms and conditions associated therewith has been
                  provided to FAIRCHILD, including a list of all shareholders,
                  options, Warrants, puts and other instruments that may affect
                  FAIRCHILD's equity position after shareholdings are fully
                  diluted;

         (h)      there are no material written or oral agreements with any
                  other person or corporation pursuant to which Praxis or it
                  directors or officers have agreed to do anything beyond the
                  requirements of the formal written contracts referred to in
                  clause (e);

<PAGE>
                                      -7-

         (i)      the transfer of the Shares to Praxis contemplated by this
                  Agreement will not constitute a breach of any contract or
                  commitment to which FAIRCHILD is a party;

         (j)      Praxis has filed all necessary tax returns;

         (k)      this Agreement has been duly authorized, executed and
                  delivered by Praxis and is a legal, valid and binding
                  obligations of Praxis enforceable by FAIRCHILD in accordance
                  with its terms, except as enforcement may be limited by
                  bankruptcy, insolvency and other laws affecting the rights of
                  creditors generally;

         (l)      the execution and delivery of this Agreement by Praxis and the
                  completion of the transactions herein will not result in a
                  breach or violation of any of the provisions of any obligation
                  of Praxis under any contract to which Praxis may be a party;
                  any judgment, decree, order or award of any court,
                  governmental body or arbitrator having jurisdiction over
                  Praxis; or any applicable law, statute, ordinance, regulation
                  or rule;

         (m)      the issue of the Shares to Praxis is in compliance with the
                  constating documents of FAIRCHILD; and

         (n)      Praxis is not a non-resident of Canada within the meaning of
                  Section 116 of the Income Tax Act (Canada).


(3)               If at any time prior to the Closing Date:

         (a)      Praxis shall have failed to comply with any term or condition
                  contained herein;

         (b)      any representations and warranties set out in Section 6(2) is
                  incorrect in any material respect;

         (c)      there is any material default under debts owed by Praxis which
                  default has not been cured within any applicable grace period;
                  or

         (d)      any material final judgments are rendered against Praxis;


FAIRCHILD may terminate this Agreement upon written notice to Praxis.

<PAGE>
                                       -9-

(4) All registration and recording fees payable to third parties in connection

with the closing of the transactions outlined in this Section 6 shall be borne

by Praxis.

SECTION 7 - PURCHASE OF ADDITIONAL SHARES

                  Praxis shall not purchase any Shares in addition to those to

which Praxis is entitled pursuant to Section 6 unless such purchase is made in

conjunction with or pursuant to an agreement between Praxis and FAIRCHILD for

the acquisition by Praxis of voting control of FAIRCHILD.

                       PART III - RESEARCH AND DEVELOPMENT

SECTION 8 - RESEARCH PROJECTS

(1) Praxis shall conduct the Research Projects and perform all work described in

Schedule "C".

(2) Praxis shall commence work on October 1st, 1999 and shall use reasonable

efforts to complete the Research Projects in accordance with the work schedule

included as part of Schedule "C".

(3) The Research Projects shall be performed by Praxis in a thorough and

diligent manner in accordance with Good Laboratory Practices and normal

professional standards.

(4) Praxis shall report to FAIRCHILD at the times and in the manner set forth in

Schedule "C".

(5) FAIRCHILD shall pay to Praxis the total sum of $250,000.00 USD, after

deduction for any loans to the company, payable as an initial payment of $62,500

USD


<PAGE>
                                      -10-

and then in three equal quarterly instalments of $50,000 USD payable on the

first day of each month commencing on January 1st, 2000 and a single, and final,

quarterly payment of $37,500 USD on October 1st, 2000, such payments to be

exclusive of any taxes, whether municipal, provincial, federal or Goods and

Services. The funds paid by FAIRCHILD to Praxis pursuant to this Section 8 shall

only be used by Praxis for the conduct of the Research Projects and shall only

be expended in accordance with the budget included as part of Schedule "C",

unless Praxis obtains prior written authorization from FAIRCHILD.

(6) FAIRCHILD and Praxis shall, not less than once every three (3) months,

review and evaluate progress on the Research Projects. Following such reviews

milestones as set out in Schedule C may be revised as and when needed by mutual

agreement between FAIRCHILD and Praxis.

(7) Praxis shall use reasonable efforts to ensure that the technology used in

the Research Projects does not infringe on any patents or proprietary rights of

other persons.

SECTION 9 - RECORDS AND CONFIDENTIALITY

(1) Praxis shall maintain complete and accurate records of the activities

conducted and results obtained pursuant to the Research Projects, all in

accordance with good scientific practice. Upon written request from FAIRCHILD,

Praxis shall provide copies of any such records to FAIRCHILD.

(2) Praxis shall keep full, accurate and complete records of books of account

relating to financial aspects of the Research Projects. FAIRCHILD, or a

designate of FAIRCHILD, may from time to time upon reasonable prior written

notice to Praxis examine, audit or have examined or audited the records and

books of account of Praxis.

<PAGE>
                                      -11-

(3) All data, reports, plans, records, logs and other information relating to

the Research Projects shall be treated by Praxis and FAIRCHILD as the

confidential property of both parties and both parties shall use all reasonable

efforts to ensure that such information is kept strictly confidential during the

term of this Agreement and for a period of ten (10) years thereafter. Nothing

herein shall prevent Praxis from using, disclosing or authorizing disclosure of

information:

         (a)      which is or becomes part of the public domain through no act

                  or failure on the part of Praxis;

         (b)      which was in Praxis' possession prior to its development

                  pursuant to the Research Projects or prior to receipt or

                  acquisition from FAIRCHILD;

         (c)      which is disclosed to Praxis by a third party without a

                  covenant of confidentiality, provided that such third party

                  is, to the knowledge of Praxis, under no obligation of

                  confidentiality with respect to the information; or

         (d)      with the prior written authorization of FAIRCHILD.


SECTION 10 - OWNERSHIP OF NEW INTELLECTUAL PROPERTY


(1) New Intellectual Property shall promptly be disclosed by Praxis to FAIRCHILD

and thereafter shall be included as part of the Licensed Technology and licensed

to FAIRCHILD pursuant to Section 11.

(2) All expenses connected with preparing, filing, prosecuting, obtaining,

maintaining and enforcing intellectual property rights related to the New

Intellectual Property shall be borne by FAIRCHILD.

<PAGE>
                                      -12-
                                PART IV - LICENCE

SECTION 11 - GRANT


(1) Praxis hereby grants to FAIRCHILD an exclusive, world-wide sublicence under

the Licensed Patent Applications and Licensed Patents, and an exclusive,

world-wide sublicence under the New Intellectual Property, to use the Licensed

Technology and to make, use and sell any products, compounds, compound uses,

processes, applications, methods or procedures within the Field of Use.


(2) FAIRCHILD shall be entitled to grant further sublicences of the rights

granted by Praxis to FAIRCHILD pursuant to Section 11(1) hereof. FAIRCHILD shall

advise Praxis in writing of any and all sublicences granted by FAIRCHILD in

accordance with this Section 11(3) and shall provide Praxis with the following

information:

         (a)      name of the sublicencee;

         (b)      the amount of any licence fee or royalties payable by the

                  sublicencee; and

         (c)      such further information as may be reasonably requested by

                  Praxis.


(3) FAIRCHILD may assign this Agreement to an Affiliate of FAIRCHILD or may

transfer or assign the rights and obligations of FAIRCHILD pursuant to Parts

III, IV or V, or any combination thereof, to an Affiliate of FAIRCHILD.

FAIRCHILD shall advise Praxis in writing of any such transfer or assignment.

Notwithstanding any such transfer or assignment, FAIRCHILD shall at all times

remain liable to Praxis for the performance of the obligations set out herein,

including the obligation to pay to Praxis a share of Net Revenue in accordance

with Section 12.

<PAGE>
                                      -13-
SECTION 12 - REVENUE


(1) Net Revenue shall be apportioned between the parties and FAIRCHILD shall pay

to Praxis an amount equal to thirty five percent (35%) of Net Revenue of Praxis

products for so long as there are Valid Claims.

(2) All payments required to be made pursuant to Section 12(1) shall be made

according to Section 8(5).

SECTION 13 - RECORDS AND REPORTS


(1) FAIRCHILD shall keep full, accurate and complete records and books of

account relating to Net Revenue and any amounts payable by FAIRCHILD to Praxis

pursuant to Section 12 hereof.

(2) All payments made by FAIRCHILD to Praxis pursuant to Section 12 shall be

accompanied by a report providing such information as is reasonably required by

Praxis to determine an accurate determination of the amounts payable by

FAIRCHILD to Praxis in accordance with Section 12.

(3) Praxis may from time to time, upon reasonable prior notice to FAIRCHILD have

the records and books of account maintained by FAIRCHILD in accordance with

Section 13(1) hereof audited or examined by a duly authorized independent

chartered accountant to ascertain the accuracy of the payments made. All costs

of any audit, examination or report shall be payable by Praxis, unless the

report discloses an underpayment of five (5%) percent or more, in which case the

cost of the audit, examination or report shall be payable by FAIRCHILD.

SECTION 14 - PROTECTION, ENFORCEMENT AND INFRINGEMENTS



<PAGE>
                                      -14-

(1) Praxis shall permit FAIRCHILD to control and direct (including the selection

of patent agents or patent attorneys) the preparation, filing and prosecution of

all patent applications the subject of this Agreement included within the Field

of Use of the Licensed Technology, including the New Intellectual Property.

Without limiting the generality of the foregoing, Praxis shall, upon FAIRCHILD's

request and at FAIRCHILD's cost and expense, file and prosecute patent

applications to protect the Licensed Technology in any country that a patent

application has not been filed. FAIRCHILD shall consult with Praxis on the

content of all patent applications and related filings. Praxis shall bear all

costs related to the preparation, filing, prosecution and maintenance with

respect to the Licensed Patents described on Schedule "A", the Licensed Patent

Applications described in Section 1(g)(i) and any other patents or Licensed

Patent Applications that disclose and claim the same inventions. FAIRCHILD shall

pay all costs of preparing, filing, prosecuting and maintaining all Licensed

Patent Applications and Licensed Patents related to the New Intellectual

Property.

(2) If either party believes that any Licensed Patents are being infringed by

another person, that party shall promptly notify the other party and shall

provide any evidence of infringement which is reasonably available. FAIRCHILD

shall have the first right and option, but not the obligation, to bring an

action for infringement, at FAIRCHILD's sole cost and expense, against the

alleged infringer. If FAIRCHILD elects to take such action, the conduct of the

action shall be entirely under the direction and control of FAIRCHILD. If

FAIRCHILD exercises the rights contained herein, FAIRCHILD may name Praxis as a

party plaintiff in such action, suit or proceeding, if reasonably necessary

under the circumstances, provided that FAIRCHILD shall indemnify and hold Praxis

and Anutech harmless from any costs or expenses incurred in connection with such

action, suit or proceeding. Any damages or sums recovered by FAIRCHILD in any

such action, suit or proceeding, or any settlement thereof, shall be retained by

FAIRCHILD, but, to the extent that the recovery reflects lost sales of Licensed

Products, the net amount after deducting expenses incurred by FAIRCHILD, shall

be included as part of Net Revenue.

<PAGE>
                                      -15-

(3) If FAIRCHILD elects not to pursue an action for infringement, whether alone

or jointly with Praxis, Praxis shall have the right and option, but not the

obligation, at Praxis's sole cost and expense, to bring the action for

infringement against the alleged infringer. Any damages or sums recovered by

Praxis in such action, suit or proceeding, or any settlement thereof, shall be

retained by Praxis, but, to the extent that the recovery reflects lost sales of

Licensed Products, Praxis shall pay to FAIRCHILD one-half of the net amount

after deducting expenses incurred by Praxis.


(4) The parties shall cooperate in defending any impeachment, interference or

infringement action, suit or proceeding brought against either Praxis or

FAIRCHILD related to the Licensed Technology.


(5) The parties shall not take any actions that may be reasonably known to

compromise the position of the other party with respect to legal proceedings

commenced or to be commenced or being defended by the other party.


(6) The parties shall render all reasonable assistance, including providing all

documents in their possession and any witnesses as are or may be required in the

conduct of any proceedings referred to herein. If any party renders such

assistance at the request of another party, the requesting party shall reimburse

the assisting party for expenses incurred to render such assistance.

SECTION 15 - WARRANTIES, INDEMNITIES AND INSURANCE


(1) Praxis represents and Warrants to FAIRCHILD that, as of the Closing Date:


         (a)      Praxis owns or has valid and enforceable licenses of the
                  Licensed Technology free and clear of all liens, charges,
                  security interests

<PAGE>
                                      -16-
                  and encumbrances, licences and other restrictions;

         (b)      the Anutech Licence Agreement is in full force and effect,
                  unamended and that neither Praxis nor Anutech are in default
                  of any of the terms and conditions contained therein;

         (c)      to the best of Praxis's knowledge and belief, the practising
                  of the Licensed Technology will not infringe the rights of any
                  other person; and

         (d)      to the best of Praxis's knowledge and belief, it is not aware
                  of any activities or conduct of any other person that would
                  constitute infringement of the Licensed Technology.


(2) The parties shall assume and be liable for their own losses, damages and

expenses of any nature whatsoever which they may suffer, sustain, pay or incur

by reason of any matter or thing arising out of, or in any way related to this

Agreement, except for such losses, costs, damages and expenses as are the result

of the wilful breach of any term herein by the other party or the wilful or

negligent acts or omissions of the other party.


(3) Each party shall indemnify and hold harmless the other party, its employees

and agents, from and against any and all claims, demands and costs whatsoever

that may arise out of, directly or indirectly, the indemnifying party's

performance of this Agreement or that of the indemnifying party's employees or

agents. Such indemnifications shall survive this Agreement.


(4) Praxis shall, at its own expense and without limiting its liabilities

herein, maintain comprehensive or commercial general liability insurance with an

insurer in an amount not less than $1,000,000.00 per occurrence (annual general

aggregate, if any, not less than $2,000,000.00), insuring against bodily injury,

personal injury and property damage, including loss of use thereof. Such

insurance shall include blanket contractual liability.

<PAGE>
                                      -17-
(5) From the date that any Product arising out of the the Licenced Technology is

first applied for therapeutic human use (and for the term or foreseeable term of

the human use) FAIRCHILD undertakes to hold product liability insurance to the

value of at least $10,000,000.00. Such policies shall name Praxis as additional

insureds and shall be purchased from a reputable insurer. Certificates

evidencing the coverage shall be provided to Praxis.


SECTION 17 - REGULATORY APPROVALS

(1) FAIRCHILD shall use reasonable efforts to obtain Regulatory Approvals.

(2) Praxis shall assist FAIRCHILD in obtaining Regulatory Approvals in the

various countries by providing such information and data as may be in the

possession of Praxis necessary for or of assistance in obtaining any Regulatory

Approvals. FAIRCHILD shall be responsible for all regulatory, agency, filing,

inspection and other fees and expenses and charges incurred in connection with

obtaining any Regulatory Approvals pursuant to Section 17(1).


(3) Praxis shall ensure that all information and data generated by Praxis that

is related to the Clinical Trials or would be of any assistance to FAIRCHILD in

obtaining Regulatory Approvals shall be maintained in a form suitable for

submission to regulatory authorities and shall at all times be kept secure and

confidential.

                                PART VI - GENERAL

SECTION 18 - TERM AND TERMINATION


(1) The term of this Agreement shall expire on the expiration of the last

Licensed Patent. Upon the expiration of this Agreement, FAIRCHILD's licence


<PAGE>
                                      -18-
pursuant to Section 11 shall become a fully paid-up, perpetual licence.

(2) This Agreement may be terminated at any time upon the mutual agreement of

the parties.

(3)               If:

         (a)      either party has breached any of its obligations pursuant to
                  this Agreement and fails to remedy such breach or to commence
                  and diligently pursue reasonable steps to remedy such breach
                  within sixty (60) days after notice in writing from the other
                  party;

         (b)      either party becomes bankrupt or insolvent or takes the
                  benefit of any statute for bankrupt or insolvent debtors or
                  makes any proposal, assignment or arrangement with its
                  creditors, or any steps are taken or proceedings commenced by
                  any person for the dissolution, winding up or termination of
                  either parties existence or the liquidation of its assets; or

         (c)      a trustee, receiver, receiver manager or like person is
                  appointed with respect to the business or assets of a party;


the party in default may terminate this Agreement by giving written notice to

the party in default.

(4) If Praxis is in default of any of its obligations related to the performance

of the Research Projects, and has failed to remedy such breach within sixty (60)

days after notice in writing from FAIRCHILD, FAIRCHILD may terminate the

Research Projects immediately upon written notice to Praxis. If FAIRCHILD

terminates the Research Projects in accordance with this Section 18(4):

         (a)      FAIRCHILD shall reimburse Praxis for costs and expenses
                  incurred in accordance with the budget included as part of
                  Schedule "C" to the date of termination;

         (b)      FAIRCHILD shall have no further obligation with respect to the
                  conduct of

<PAGE>
                                      -19-
                  the Research Projects or any costs and expenses related
                  thereto;

         (c)      notwithstanding the termination of the Research Project, all
                  New Intellectual Property developed prior to the date of
                  termination shall be disclosed by Praxis to FAIRCHILD and
                  shall be included as part of the Licensed Technology and
                  licensed to FAIRCHILD pursuant to Section 11; and

         (d)      FAIRCHILD shall have the right to complete the Research
                  Project, or any part thereof at its own cost and expense and
                  any results; improvements to Intellectual Property sublicenced
                  from Praxis under the terms of this Agreement; new patents and
                  patent applications arising from this shall be deemed to be
                  New Intellectual Property.


(5) The following sections shall survive termination of this Agreement: 1, 2, 3,

4, 5, 9 and 15.

SECTION 19 - PUBLICITY


(1) A copy of all public announcements and press releases which either party

intends to release or make regarding products or technology covered by the

licence shall be provided to the other party prior to being released or made.

Any public announcement or news release that names, refers to or in any way

identifies both parties shall be approved by both parties prior to being

released or made. Each party shall respond to a request for approval within five

(5) working days of receipt of the copy and the approval of each party shall not

be unreasonably withheld.


(2) If either party is prevented from complying with Section 19(1) as a result

of the requirements of a Securities Commission or other regulatory body, the

party shall not be considered to be in breach of this Agreement, but shall use

reasonable efforts to consult with and keep the other party informed.


(3) The parties shall not use each other's name in any advertising material

without the prior written consent of the other party, which consent may be

arbitrarily

<PAGE>
                                      -20-
withheld.


(4) Subject to subsection (3), FAIRCHILD shall be responsible for and have
control of labelling of Licensed Products.


SECTION 20 - COMPLIANCE WITH LAWS


                  The parties shall observe and comply with all applicable laws,

ordinances, codes and regulations of Government agencies, including Federal,

Provincial, Municipal and local governing bodies having jurisdiction.

SECTION 21 - RELATIONSHIP


                  Nothing in this Agreement shall be construed as:

         (a)      constituting either party as the agent, employee or
                  representative of the other party; or

         (b)      creating a partnership or as imposing upon either party any
                  partnership duty, obligation or liability to the other party.


SECTION 22 - NOTICES


                  All notices or other communications required or permitted to

be given hereunder shall be in writing and shall be sent to the following

addresses or such other addresses as the relevant party may notify from time to

time:

                           TO: William B Cowden, CEO
                           Praxis Pharmaceuticals Inc.
                           GPO Box 1978
                           Canberra, ACT, Australia 2601
                           Facsimile: 61 2 6279 9758

<PAGE>
                                      -21-

                           TO:  Byron Cox
                           FAIRCHILD INTERNATIONAL Inc.
                           #600 - 595 Hornby Street
                           Vancouver, British Columbia   V6C 1A4
                           Facsimile:  (604) 646-5649


Notices sent by prepaid registered mail shall be deemed to be received by the

addressee on the 7th day (excluding Saturdays, Sundays, statutory holidays and

any period of postal disruption) following the mailing thereof. Notices

personally served or transmitted by facsimile shall be deemed received when

actually delivered or transmitted, provided such delivery shall be made during

normal business hours.


SECTION 23 - ASSIGNMENT


                  Except as expressly permitted pursuant to Section 11, the

parties shall not assign this Agreement or any part thereof, or any rights

hereunder without the prior written consent of the other party, such consent not

to be unreasonably withheld.


SECTION 24 - FURTHER ASSURANCES


                  The parties shall with reasonable diligence take all action,

do all things, attend or cause their representatives to attend all meetings and

execute all further documents, agreements and assurances as may be required from

time to time in order to carry out the terms and conditions of this Agreement in

accordance with their true intent.


SECTION 25 - SETTLEMENT OF DISPUTES


(1) If there is any dispute or disagreement related to or arising out of this

Agreement (the "Disagreement") the parties shall refer the Disagreement for

resolution

<PAGE>
                                      -22-
to their respective Chief Executive Officers, or their nominees.


(2) If the Disagreement is not resolved pursuant to Section 25(1) within thirty

(30) days (or such longer period as agreed upon between the parties), a mediator

shall be appointed by the parties who shall assist the parties in resolving the

Disagreement.


(3) If the Disagreement is not resolved under Section 25(2) within thirty (30)

days (or such longer period as agreed upon between the parties) either party may

refer the Disagreement to be resolved by arbitration conducted as follows:


         (a)      either party may require arbitration by giving written notice
                  to arbitrate to the other party, which written notice shall
                  identify the nature of the Disagreement;

         (b)      if the parties are able to agree upon a single arbitrator, the
                  arbitration shall be conducted before the single arbitrator;

         (c)      if the parties have been unable to agree upon the selection of
                  a single arbitrator within two (2) weeks after receipt of the
                  notice requiring arbitration, each party shall within one (1)
                  further week, by notice in writing given to the other party,
                  nominate one neutral arbitrator. If either party fails to
                  nominate an arbitrator in accordance with this clause, the
                  arbitrator so nominated shall proceed to conduct the
                  arbitration alone. If both parties nominate neutral
                  arbitrators in accordance with this clause, the two
                  arbitrators so nominated shall nominate a third arbitrator
                  within one (1) week of their nomination;

         (d)      the arbitrator or arbitrators shall immediately proceed to
                  hear and determine the Disagreement. The parties agree that it
                  is important that all Disagreements be resolved promptly and
                  the parties therefore agree that the arbitration shall be
                  required to be conducted expeditiously and that the final
                  disposition shall be accomplished within two (2) weeks. The
                  parties shall ensure that the arbitrator or arbitrators upon
                  accepting the nomination shall agree that the arbitrator has
                  time available for the timely handling of the arbitration in
                  order to achieve final disposition within two (2) weeks;

         (e)      the decision of the arbitrator or arbitrators shall be
                  rendered in writing, without reasons and shall be promptly
                  served upon both parties. If the

<PAGE>
                                      -23-

                  arbitration is being conducted before a panel of three
                  arbitrators, the decision of any two of the three arbitrators
                  shall be decision of the arbitration panel. The decision of
                  the arbitrator or arbitrators shall be binding upon the
                  parties;

         (f)      in the event of the death, resignation, incapacity, neglect or
                  refusal to act of any arbitrator, and if the neglect or
                  refusal continues for a period of five (5) days after notice
                  in writing of such has been given by either party, another
                  arbitrator shall be nominated to replace the arbitrator by the
                  person who has originally nominated that arbitrator;

         (g)      the costs of the arbitration shall be in the discretion of the
                  arbitrators, and shall be borne by the parties in accordance
                  with the decision of the arbitrators;


SECTION 26 - ENUREMENT

                  This Agreement shall enure to the benefit of and be binding

upon the parties hereto and their respective successors and permitted assigns.


                  IN WITNESS WHEREOF the parties hereto have executed this

Agreement as of the day and year first above written.

                                PRAXIS PHARMACEUTICALS, INC.

                                Per:      /S/ BRETT CHARLTON (PRESIDENT)

                                Per:

                                FAIRCHILD INTERNATIONAL INC.

                                Per:      /S/ BYRON COX

                                Per:



<PAGE>





DATE                                                                     1999
- --------------------------------------------------------------------------------




                                 ANUTECH PTY LTD


                                       AND


                    PRAXIS PHARMACEUTICALS AUSTRALIA PTY LTD





- --------------------------------------------------------------------------------


                           EXCLUSIVE LICENCE AGREEMENT


- --------------------------------------------------------------------------------


                                  [] DUNHILL []
                                  [] MADDDEN []
                                  [] BUTLER  []
                                   SOLICITORS


                                    AMP Tower
                                 1 Hobart Place
                             CANBERRA CITY ACT 2600
                               Tel: (02) 6218 6500
                               Fax: (02) 6218 6525
                                 Ref: G. Marques


                    BRISBANE o CANBERRA o MELBOURNE o SYDNEY


<PAGE>


THIS AGREEMENT is made on the 14th day of October 1999

BETWEEN

ANUTECH  PTY LTD A.C.N.  008 548 650 of Anutech  Court,  Corner  Barry Drive and
Daley Roads, Australian Capital Territory, Australia 2601

                                                                     ("ANUTECH")


AND


PRAXIS  PHARMACEUTICALS  AUSTRALIA  PTY  LTD  A.C.N.  082  811  630  having  its
registered  office at Duesburys,  60 Marcus Clarke Street,  Canberra City A.C.T.
2601

                                                                      ("PRAXIS")

WHEREAS

A.       Anutech  is  the  commercial  subsidiary  of  the  Australian  National
         University  ("ANU") and regularly  provides  services to its clients by
         engaging  the  services of the ANU and does so within the field of this
         Agreement.

B.       ANU is the  proprietor  of certain  patents and is the owner of certain
         other related intellectual property and has agreed to grant to Praxis a
         licence of such  patents  and  intellectual  property  on the terms and
         conditions set out herein.

C.       Praxis wishes to obtain an exclusive  licence within the Licensed Field
         of such patents and  intellectual  property,  and to then undertake the
         research,  development  and  Exploitation  of products  based upon such
         patents.



IT IS AGREED

1.       INTERPRETATION

1.1      DEFINITIONS

         In this agreement, unless the context otherwise requires, the following
         words shall have the following meanings:-

         "ANU INTELLECTUAL   PROPERTY"   means   the   Licensed   Patents,   any
              Intellectual  Property  relating to the Licensed Patents or actual
              or  potential  Products  or  Processes  which  is owned by ANU and
              provided  by ANU to Praxis  during  the  Term,  and  includes  any
              Intellectual   Property   developed  under  the  Research  Funding
              Agreement.

         "BUSINESS  DAY"  means a day on which  the  trading  banks are open for
              general banking business in Canberra, Australia.

- --------------------------------------------------------------------------------
ANUTECH/Praxis                     Page 1 of 1

<PAGE>

         "COMMENCEMENT DATE" means the date of execution of this Agreement.

         "CONFIDENTIAL INFORMATION" means any information whether written, oral,
              electronic  or in any other form which is  disclosed by a party or
              its  representatives,  is  claimed as  confidential  to itself and
              which relates to the ANU Intellectual Property, Improvements, this
              agreement and business of the parties.  It includes all copies and
              notes  generated from the disclosure and each party shall keep and
              maintain  confidential any further  information  which may come to
              the other parties knowledge as a result of this Agreement.

         "DOLLARS" or "$" means Australian dollars.

         "EXPLOIT" means in respect of a:

         (a)      Product - to make, have made, hire, sell or otherwise  dispose
                  of the  Product,  to offer to make,  sell,  hire or  otherwise
                  dispose of the Product, to use or import it or keep it for the
                  purpose of doing any of those things;

         (b)      Process - use the  method or  process or do any act in respect
                  of a  product  resulting  from  such use  which  falls  within
                  paragraph (a).

         "FINAL JUDGMENT"  means a judgment or decree which  becomes not further
              appealable or reviewable through the exhaustion of all permissible
              applications for appeal, rehearing or review by any superior court
              or tribunal or through the  expiration of time  permitted for such
              applications.

         "GST" means a tax on goods and  services  as  defined  by  Commonwealth
              legislation.

         "IMPROVEMENTS" means any new Intellectual  Property or any improvement,
              innovation,  invention or  development  relating to the  function,
              design,  formulation,  features,  or process of manufacture of any
              Product.

         "INDEMNIFIED PARTIES" means ANU and Anutech and any of their directors,
              officers, employees, staff, students and agents.

         "INTELLECTUAL PROPERTY" means any copyright, design (whether registered
              or unregistered),  trademark (whether registered or unregistered),
              circuit layout,  knowhow,  confidential  information (whether such
              information is in writing or recorded in any other form) and other
              proprietary or personal rights arising from intellectual  activity
              in the industrial or scientific fields.

         "LICENCE"  means the right and  licence  granted  by  Anutech to Praxis
              pursuant to this agreement.

         "LICENSED FIELD" means the use of phosphosugars as ethical therapeutics
              and expressly excludes:

         (c)       the use of  phosphosugars as  neutriceuticals,  complementary
                   medicines or cosmetics  for the  treatment of any  applicable
                   condition;

         b)        topical application for wound care; and

         c)        the    use    of    fructose-1,6-diphosphate,    administered
                   non-topically,  for the treatment or prophylaxis of ischaemic
                   disorders  in  humans,  which  includes  transplantation  and
                   immunosuppression.

- --------------------------------------------------------------------------------
ANUTECH/Praxis                     Page 2 of 2

<PAGE>

         "LICENSED PATENTS" means the patents and patent  applications listed in
               SCHEDULE 1 and includes:

            a) any    continuations,    continuations   in   part,    divisions,
               registrations, confirmations, reissues, renewals or extensions of
               term of any of those patents;

            b) any corresponding  patent or patent application as defined in the
               Patents  Act 1990  (Cth)  or any  substantially  similar  form of
               protection  for  inventions  granted  by any other  country,  the
               essence  of  which  is a right  in the  holder  of  such  form of
               protection to an exclusive right to work the relevant  invention,
               taken out or applied for in any country in the Territory which is
               fairly based upon or derived from any of those patents;

            c) any  re-issue,  renewal or  extension  of such a patent or patent
               application  (whether  in  whole or in part)  and any  patent  of
               addition thereto.

            d) any  patent  or  patent  application  which  is  dominated  by or
               dominates those patents.

         "MARKETING" means the promotion, advertising,  distribution and sale of
                  Products and includes a product launch campaign.

         "NET  REVENUE" means all amounts received by, at the direction of or on
               behalf of Praxis or any Sub-Licensee (or any Related  Corporation
               of  either  of them)  in  connection  with  the ANU  Intellectual
               Property or Products or Process less:

            a)    transport and insurance  related charges  actually allowed and
                  taken;

            b)    trade,  quantity or cash discounts or rebates actually allowed
                  and taken;

            c)    credits  or  allowances  given  or made on  account  of  price
                  adjustments,  recalls or  destruction  requested or made by an
                  appropriate government agency; and

            d)    any Tax, excise or other government charge upon or measured by
                  the sale, transportation, delivery or use of the Product which
                  is actually incurred by the seller;

         but does not  include any amount in respect of which a royalty has been
         fully  paid by  Praxis to  ANUTECH  under  clause 3 and which  shall be
         calculated  without any deduction for amounts referable to any research
         or development undertaken by Praxis or its Affiliates or ANU, including
         for  example  pre-clinical  research  and  clinical  studies  and where
         applicable in accordance with clause 5 (GST).

         "PARTY"  means Anutech or Praxis and their  respective  successors  and
                  permitted assigns and "PARTIES" means both of them.


         "PRODUCTS" means any  matter,  article or thing which  incorporates  or
                  arises  from the  whole  or  partial  use of ANU  Intellectual
                  Property.

         "PROCESS"means any process or method of  manufacture in relation to the
                  operation, means of working or manufacture of a Product.

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ANUTECH/Praxis                     Page 3 of 3

<PAGE>

         "QUARTER"means each period of three months  commencing  on the first of
                  each January, April, July and October during the Term.

         "REGISTRATION"  in  respect  of a  country  means  the  gaining  of all
                  permissions  from all  Regulatory  Authorities in that country
                  necessary  to permit the  commencement  of  Marketing  in that
                  country and  includes  any approval in respect of packaging or
                  labelling.

         "REGULATORY AUTHORITY" in respect of a country means any and all bodies
                  and  organisations  regulating the importation,  distribution,
                  marketing or sale of the Product in any part of that country.

         "RELATED CORPORATION"   has  the  same  meaning  as  is  given  to  the
                  expression  "RELATED BODY CORPORATE" in the  Corporations  Act
                  1989 of the Commonwealth of Australia.

         "RESEARCHFUNDING  AGREEMENT"  means the agreement  between  Anutech and
                  Praxis,  dated on or about  the date of this  Agreement  which
                  provides  for the funding by Praxis of certain  research to be
                  undertaken by Anutech.

         "ROYALTY PERIOD"  means each Quarter Year during the Term provided that
                  where the Term commences or ends on a day other than first day
                  of a Quarter  Year the first and last reports will be for only
                  so much of the Royalty Period as occurs during the Term.

         "SUB-LICENSEE" means any person who:

            a) becomes  entitled to exercise any of the rights granted to Praxis
               under this agreement, whether directly or indirectly or;

            b) receives  Product from Praxis or any  Sub-Licensee  for a purpose
               which  includes or could  reasonably  be regarded as including or
               with the intention of re-sale.

         "TAX" means any Tax (including any GST), withholding tax, charge, rate,
               duty or impost imposed by any authority, but does not include any
               income or capital gains tax.

         "TERM"means  the  period  during  which  this  agreement  is  in  force
               pursuant to clause 14.

         "TERRITORY" means the whole of the world.

         "YEAR"means each period of twelve  months  commencing  on the first day
               of each January during the Term.

1.2      CONSTRUCTION

         In this agreement unless the context otherwise requires:-

            a) words  importing  the singular  include the plural and vice versa
               and words importing any gender include the other genders;

            b) references to persons include corporations and bodies politic;

            c) references  to a person  include  the  successors  and  permitted
               assigns of that person;

            d) a reference to a statute,  ordinance,  code or other law includes
               regulations  and  other  statutory   instruments   under  it  and
               consolidations,  amendments, re-

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ANUTECH/Praxis                     Page 4 of 4

<PAGE>

               enactments or replacements of any of them (whether of the same or
               any other legislative authority having jurisdiction);

            e) references to this or any other document  include the document as
               varied  or  replaced,  and  notwithstanding  any  change  in  the
               identity of the parties;

            f) references  to  writing  include  any  mode  of  representing  or
               reproducing  words in tangible and permanently  visible form, and
               include telex and facsimile transmissions;

            g) an  obligation of two or more parties shall bind them jointly and
               severally  and an  obligation  incurred  in favour of two or more
               parties shall be enforceable by them jointly and severally;

            h) if a word or phrase is defined,  cognate  words and phrases  have
               corresponding definitions;

            i) references  to a body  which  has  ceased  to  exist  or has been
               reconstituted,  amalgamated,  reconstructed  or  merged,  or  the
               functions of which have become exercisable by any other person or
               body in its place,  shall be taken to refer to the person or body
               established  or constituted in its place or the person or body by
               which its functions have become exercisable;

            j) reference  to  any  thing  (including,  without  limitation,  any
               amount)  is a  reference  to the  whole  or any  part of it and a
               reference  to a group of things or persons is a reference  to any
               one or more of them;

            k) references to this agreement include its schedules;

            l) headings shall be ignored in construing this agreement; and

            m) if any day  appointed  or  specified  by this  agreement  for the
               payment of any money or the doing of any act or thing  falls on a
               day that is not a Business Day, the day so appointed or specified
               shall be deemed to be the next day which is a Business Day;

            n) no provision of this Agreement  will be construed  adversely to a
               party solely on the ground that the party was responsible for the
               preparation of this Agreement or that provision; and

            o) an expression  importing a natural  person  includes any company,
               partnership,  joint  venture,  association,  corporation or other
               body corporate and any government, governmental,  administrative,
               judicial or semi-governmental agency or body.

1.3      PRECEDENCE

         The documents  comprising this agreement shall be read in the following
order of precedence:

            a) the clauses in the body of this agreement; then

            b) the paragraphs in the body of the schedules.

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ANUTECH/Praxis                     Page 5 of 5

<PAGE>

         Where any conflict  occurs between the  provisions  contained in two or
         more of the documents  forming this  agreement,  the documents lower in
         the order of  precedence  shall where  possible be read down to resolve
         such  conflict.  If the conflict  remains  incapable of  resolution  by
         reading  down,  the  conflicting  provisions  shall be severed from the
         document  lower  in the  order of  precedence  without  (to the  extent
         possible)  otherwise  diminishing the  enforceability  of the remaining
         provisions of that document.

2.       GRANT OF LICENCE

2.1      GRANT OF LICENCE

         Anutech   hereby   grants  to  Praxis  with  effect  on  and  from  the
Commencement Date an exclusive licence, to:-

            a) Exploit (within the Licensed Field) the Products and Processes in
               the Territory utilising the ANU Intellectual Property; and

            b) use the ANU  Intellectual  Property within the Licensed Field for
               the purposes of further  research and  development and to Exploit
               the results of such further research and development.

2.2      ANUTECH'S RIGHTS

         Anutech and Praxis agree and acknowledge  that during the Term,  except
         as set out in or permitted by this agreement Anutech shall not:-

            a) Exploit the Products  within the Licensed  Field in the Territory
               utilising the ANU Intellectual Property;

            b) use the ANU  Intellectual  Property except for the purpose of its
               own internal research.

3.       ROYALTIES

            a) In consideration  for the grant of the Licence Praxis will pay to
               Anutech a royalty of 2% of Net Revenue.

            b) The  obligation  in clause 3(a) survives the  termination  of the
               Licence and this Agreement.

4.       REPORTS

4.1      REPORTING REQUIREMENTS

         Praxis shall within 30 days of the end of each Royalty  Period  provide
to Anutech a written report setting out:

            a) the total  quantity of Products sold or provided by it and by its
               Sub-Licensees;

            b) the Net Revenue;

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ANUTECH/Praxis                     Page 6 of 6

<PAGE>

            c) the calculation of the royalty payable,  including details of the
               currency  conversion  rates  used,  any  taxes or  other  amounts
               withheld and any adjustments on account of returns.

4.2      INTEREST

         Praxis  must  pay  Anutech  interest  on all  amounts  due  under  this
         Agreement but unpaid,  calculated at the rate  applicable to overdrafts
         charged by the  Commonwealth  Bank of  Australia at the date of payment
         from the due date until the date of payment,  ,  calculated  daily from
         the due date. The payment of such interest  shall not preclude  Anutech
         from  exercising  any other  rights it may have  because any payment is
         overdue.

4.3      FOREIGN CURRENCIES

         Praxis shall  calculate  royalties in local  currencies and convert the
         same to dollars at the ruling  rate of  exchange  as on the last day of
         the Royalty Period.

4.4      PAYMENT MECHANICS

         The  royalty  payable  to  Anutech  shall  be  paid  to a bank  account
         nominated by Anutech in Canberra,  Australia (or at such other location
         in Australia as Anutech may  stipulate  from time to time) within sixty
         days of the end of each Royalty Period.

4.5      PRAXIS TO KEEP ACCOUNTS AND RECORDS

         Praxis shall keep for a period of 7 (seven)  years after the end of the
         Royalty Period to which they relate,  true and particular  accounts and
         records  of  all  sales  of  Products   sufficient  to  verify  Praxis'
         calculation  of Net Revenue  and  Products  sold,  the  calculation  of
         royalty based thereon and  conversion of such amounts into the relevant
         currency.

4.6      INSPECTION OF ACCOUNTS

         Anutech and its duly authorised representatives shall have the right to
         inspect and audit from time to time the accounts  and records  referred
         to in CLAUSE 4.6 and such other matters as are directly relevant to the
         calculation of the amount of any payment due by Praxis to Anutech under
         this agreement and shall be entitled to take copies of such records, on
         the following conditions:-

            a) inspection shall be limited to 2 times in any one Year;

            b) inspections  shall take place during  normal  business  hours and
               upon reasonable prior notice to Praxis;

            c) employees of Anutech or its duly authorised  representatives  who
               inspect  such  accounts  and records  must be suitably  qualified
               personnel reasonably acceptable to Praxis and shall:-

               i)   whilst inspecting such records and accounts, abide by all of
                    Praxis' standard rules and regulations;

               ii)  Anutech shall  indemnify  and hold Praxis  harmless from all
                    liability   resulting  from  any  negligence  or  any  other
                    activities  on the  part  of  Anutech's

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ANUTECH/Praxis                     Page 7 of 7

<PAGE>



                    employees or duly authorised representatives inspecting such
                    records and accounts.


4.7      SETTLEMENT OF DISCREPANCIES

         Anutech shall advise Praxis of the result of any audit  conducted by it
         pursuant to CLAUSE 4.6. If any discrepancy is found by Anutech then the
         amount  thereof shall by paid by the party that owes such amount within
         7 days of demand therefor by the party due such amount.

4.8      COST OF AUDIT

         Anutech  shall  bear  the  cost  of  any  such  examination  unless  an
         underpayment  of 5% or more in the  amount of any  royalty  payment  is
         detected  in  which   event   Praxis  will  bear  the  expense  of  the
         examination.

5.       GST

         The  royalty  does not include any amount on account of Tax. If any Tax
         is payable  by  Anutech in  relation  to this  Contract,  ANUTECH  WILL
         INCREASE  THE  ROYALTY ON ACCOUNT OF THE TAX.  Anutech  will adjust the
         royalty having regard to Part VB of the Trade Practices Act 1974(Cth).


6.       EXPLOITATION OF LICENSED PATENTS

6.1      PRAXIS' OBJECTIVES

         Praxis shall use reasonable endeavours at the expense of Praxis to:

         a)    Exploit Product, Process, and ANU Intellectual Property;

         b)    undertake either itself or through third parties further research
               and development based on the ANU Intellectual Property; and

         c)    as  and  when  required,  undertake  itself  or  through  Related
               Corporations,  or enter into appropriate third party licensing or
               marketing  arrangements,  to optimise  the returns  from sales of
               Products,  and to achieve  Marketing  of Products at the earliest
               practicable and economically prudent date

and Praxis must:

         d)    at its cost obtain and  maintain all  Registrations  necessary to
               allow  it  to  Exploit  the  ANU  Intellectual  Property  and  to
               manufacture and sell Products;

         e)    ensure that each Product sold:

                  (i)      is of merchantable quality;

                  (ii)     is fit for the purpose for which it is acquired;

                  (iii)    satisfies any conditions  and  warranties  implied by
                           the law of that country in which it is sold; and

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ANUTECH/Praxis                     Page 8 of 8

<PAGE>


                  (iv)     complies  with  all  laws  and  standards  regulating
                           manufacture,  assembly, labelling, packaging, storage
                           and sale in the country in which it is sold.

6.2      PRAXIS' SPECIFIC OBLIGATIONS

         Further to its general obligations in CLAUSE 6.1 Praxis agrees to:-

         a)    on a 6 monthly basis provide to Anutech a written plan  detailing
               the steps  proposed to be taken by Praxis in at least the next 12
               months to achieve the objectives set out in CLAUSE 6.1, such plan
               to include  the  budgeted  expenditure  for the next 12 months on
               such  activities in reasonable  detail;

         b)    within 5 years of the  Commencement  Date,  commence  the sale of
               Products either  directly or through one or more  Sub-Licensees ;
               and

         c)    provide to Anutech a quarterly  report as against prior plans and
               budgets  detailing all activities  carried out by or on behalf of
               Praxis pursuant to CLAUSE 6.1.

7.       SUB-LICENSING

7.1      RIGHT TO SUB-LICENCE

         Anutech  grants to  Praxis  the right to  sublicence  ANU  Intellectual
         within the Licensed  Field,  subject to the prior  written  approval of
         Anutech which shall not be unreasonably withheld.

7.2      SUB-LICENCE TERMS

         Subject  to  CLAUSE  7.1,   Praxis   shall  have  the  right  to  grant
         sub-licences of the rights granted to it to third parties provided that
         Praxis  complies  with the  obligations  set out in CLAUSE  7.2 and the
         Sub-Licensee complies with the following:-

         a)    the third party being granted the  sub-licence has the commercial
               capacity to promote and Exploit  the  relevant  Product  with due
               diligence  and  probity  and has at least  sufficient  skills and
               resources  to comply with the  obligations  placed upon Praxis in
               relation to that Product in the relevant country or countries;

         b)    the  sub-licence  is  wholly  consistent  with the  terms of this
               Licence and in particular:

               i)   such  sub-licence  does not purport to extend or continue in
                    any circumstances where this Licence may be terminated; and

               ii)  the  Sub-Licensee   acknowledges   that  ANU  owns  the  ANU
                    Intellectual Property;

         c)    the sub-licence prohibits the Sub-Licensee from taking any action
               or  allowing  any  action  to be taken  which  detracts  from the
               ownership  of the ANU  Intellectual  Property by ANU or conflicts
               with the  provisions  contained  in this  Licence in  relation to
               prosecuting  or defending  the Licensed  Patents or defending any
               allegation of infringement of the ANU Intellectual Property other
               than the Licensed  Patents;

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ANUTECH/Praxis                     Page 9 of 9

<PAGE>


         d)    the  sub-licence  is in the  English  language,  executed  by the
               sub-licensee and giving its place of business;

         e)    the sub-licence  requires the sub-licensee to maintain all books,
               records and  accounts  necessary  to enable  verification  of Net
               Revenue and royalties  and other  amounts  required to be paid by
               Praxis to Anutech and to allow  Anutech to inspect  those  books,
               records  and  accounts  on terms  similar to those  contained  in
               CLAUSE 4.5; and

         f)    the sub-licence limits the duration of the sub-licence in respect
               of the ANU  Intellectual  Property for the term of this Agreement
               and  further   provides   for  the   sub-licence   to   terminate
               automatically upon the termination of this Agreement.


7.3      RESEARCH LICENCES

         Praxis shall be entitled to grant  licences to third parties to the ANU
         Intellectual  Property  for  research  purposes  only on such terms and
         conditions as it sees fit provided  that Praxis  protects its rights to
         any commercially viable technology which may arise from such research.

8.       CONFIDENTIAL INFORMATION

8.1      OBLIGATIONS OF THE PARTIES

         Subject to CLAUSES 8.2(B) and 8.5, each party  covenants with the other
as follows:

         a)    to  keep  all  Confidential   Information   strictly  secret  and
               confidential  (including  from all its  employees,  servants  and
               agents),  exercising  at least the same degree of care as it uses
               to maintain its own confidential information;

         b)    to provide proper and secure storage for Confidential Information
               within its possession or control;

         c)    to use  Confidential  Information  only for the  purposes of this
               agreement  and not for any other  activity or purpose  whatsoever
               without the prior written approval of the other party; and

         d)    to not copy or reduce to writing or any other  medium any part of
               Confidential  Information  except as may be reasonably  necessary
               for the purposes of this agreement.

8.2      EXCEPTIONS TO OBLIGATIONS

         a)    The  obligations  of  confidence  set out in CLAUSE 8.1 shall not
               extend to Confidential Information which:-

               i)   at the  time  of  disclosure  to a  party  is in the  public
                    domain;

               ii)  after  disclosure  to a party  becomes  part  of the  public
                    domain  otherwise  than as a result of the  wrongful  act of
                    that party or one of that party's disclosees;

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ANUTECH/Praxis                    Page 10 of 10

<PAGE>


               iii) a  party  can  show  was in its  possession  at the  time of
                    disclosure and was not acquired  directly or indirectly from
                    the other party; or

               iv)  is  received  from a third  party  provided  that it was not
                    acquired  directly or  indirectly by that third party from a
                    party  to  this   agreement  or  under  an   obligation   of
                    confidence; or

               v)   is required by compulsion of law to be disclosed,

provided that:

               vi)  the onus  shall be on the party  alleging  the same to prove
                    that one of the above exceptions has application; and

               vii) in any case of uncertainty as to whether the  obligations in
                    CLAUSE  8.1  have  application  to  any  information,   such
                    information  shall be treated as subject to the  obligations
                    until advised otherwise by the party to whom the obligations
                    are owed.

         b)    Prior to either party making any disclosure of information  which
               is prima facie  Confidential  Information in circumstances  where
               the party that intends to disclose the information is of the view
               that one of the exceptions in CLAUSE 8.2(A) has  application,  it
               shall  notify the other party of the facts and  circumstances  by
               virtue of which it believes  that it is entitled to disclose  the
               information, and shall not disclose such information until either
               14 days has elapsed or the other party has  indicated its consent
               to the disclosure of such information.

8.3      RIGHTS IN CONFIDENTIAL INFORMATION

         Each party  acknowledges  and agrees  that each other  party has made a
         substantial investment in that party's Confidential Information and has
         a legitimate right to protect itself against wrongful disclosure or use
         of such Confidential Information.

8.4      TERM OF OBLIGATION

         The   obligations  in  this  CLAUSE  8  shall  survive  the  expiry  or
         termination  of  this  agreement  for  whatever   reason  and  continue
         indefinitely, subject always to the exceptions included in CLAUSE 8.2.

8.5      PERMITTED DISCLOSURES

         Each  party  ("THE  FIRST   PARTY")  shall  be  permitted  to  disclose
         Confidential  Information  belonging to another party or supplied to it
         by another  party  ("THE  OTHER  PARTY")  to such of the first  party's
         employees  as require  access to such  information  for the purposes of
         this agreement, provided that:

         a)    only such Confidential  Information as needs to be disclosed to a
               person for the  purposes of this  agreement  will be disclosed to
               that person; and

         b)    the first party shall:

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ANUTECH/Praxis                    Page 11 of 11

<PAGE>


               i)   have obtained from each such person  undertakings  in favour
                    of the other party substantially in the form of the relevant
                    obligations and  undertakings in this CLAUSE 8 (but not this
                    CLAUSE 8.5);

               ii)  be  responsible   for  the  performance  of  its  employees'
                    undertakings referred to in CLAUSE 8.5(B)(I); and

               iii) take whatever steps are reasonably necessary,  including the
                    institution of legal proceedings, to ensure that each of its
                    employees  is  bound  by  and  observes  the  terms  of  the
                    undertakings referred to in CLAUSE 8.5(B)(I).

8.6      FURTHER DISCLOSURE

         Praxis  shall be  permitted  to disclose  Confidential  Information  to
         actual  and  prospective  Sub-Licensees  to the  extent  that it  deems
         reasonably  necessary  for the purpose of carrying  out of  obligations
         under  this  agreement,   in  particular  the  research,   development,
         Exploitation   or  Marketing   of   Products,   Processes  or  the  ANU
         Intellectual Property, provided that:-

         a)    only such information as Praxis reasonably considers is necessary
               for the relevant activity is disclosed; and

         b)    the   recipient  of  such   information   agrees  to  treat  such
               information  as  confidential  and an  appropriate  agreement  to
               protect the Confidential Information is executed.

9.       USE OF NAME

         Any  proposed  use of a  party's  name by the  other  in any  published
         material  (including  prospectus  information)  must be approved by the
         other party in writing prior to release of that published material.

10.      IMPROVEMENTS BY PRAXIS

         Any Improvement  invented,  discovered or acquired by Praxis during the
         Term shall be the property of Praxis and Praxis grants to ANU a royalty
         free non-exclusive licence to use any such Improvement for the duration
         of the Intellectual  Property  protection  relating to such Improvement
         but solely for the purpose of further internal research and not for any
         commercial purpose.

11.      ADDITIONS TO LICENSED PATENTS

         Anutech  agrees to advise  Praxis  promptly of the filing of any patent
         application  or of the  issue  of  any  patent  which  are  legally  or
         beneficially owned by Anutech or ANU and which:-

         a)    are  dominated by or dominate  any patent or patent  applications
               otherwise included in Licensed Patents; or

         b)    relate to any Product or describe and claim any  improvements  in
               or to any Product or methods or  processes of making or using the
               same,

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ANUTECH/Praxis                    Page 12 of 12

<PAGE>


         whereupon,  Praxis  shall have an option to have such  patent  included
         within  Licensed  Patents,  such  option to be  exercised  by notice in
         writing to Anutech within 3 months of notification to Praxis. If Praxis
         does exercise its option then such patents or patent  applications will
         be included in Licensed  Patents without increase in the earned royalty
         rate  specified in CLAUSE 3. If Praxis does not notify  Anutech that it
         wishes to exercise the option within the period of 3 months then Praxis
         shall be deemed to have  waived all  rights  and future  rights to such
         patents  or patent  applications.  Anutech  will then have a  perpetual
         unencumbered right to negotiate  agreements relating to such patents or
         patent applications with third parties.

12.      LIABILITY

12.1     RESPONSIBILITY FOR PRODUCTS

         Praxis  shall ensure at all times during the Term that the Products are
         manufactured,  used and sold strictly in  accordance  with all relevant
         applicable  requirements  and standards of relevant  jurisdictions  and
         Praxis  will  be  responsible   for  conducting  its  own   independent
         examination and verification of the accuracy and suitability of the ANU
         Intellectual  Property  and for  ensuring the Products are suitable for
         the purposes for which they are provided.

12.2     ANUTECH AND ANU NOT LIABLE

         Except  as  otherwise  specifically  provided  in this  agreement,  the
         Indemnified  Parties  shall  not be  liable  (in  contract  or  tort or
         otherwise) to compensate Praxis for any loss howsoever arising suffered
         by  Praxis  arising  directly  or  indirectly  from  the use of the ANU
         Intellectual Property or from the sale of Products.

13.      INDEMNITIES AND INSURANCE

13.1     INDEMNITY BY PRAXIS

         (a)   Praxis agrees to indemnify the  Indemnified  Parties  against and
               hold the  Indemnified  Parties  harmless  from any and all  loss,
               liability,  damage,  claim, cost and expense  (including  without
               limitation,  reasonable  attorney's  fees)  arising  from  or  in
               connection with:

         (i)   a breach by Praxis of any of its warranties or obligations  under
               this agreement;

         (ii)  the Exploitation of the Products by Praxis;

         (iii) the storage, use, sale, shipping and Marketing of the Products by
               Praxis;

         (iv)  any representations, express, implied or statutory made by Praxis
               as to the  efficacy or safety or use to be made by any  purchaser
               of the Products including,  without  limitation,  representations
               made by reference to the labelling or packaging or the Products;


         provided that Praxis shall not be required to indemnify the Indemnified
         Parties with respect to any loss,  liability,  damage,  claim,  cost or
         expense  to  the  extent  it  results  from  the  Indemnified  Parties'
         negligence or breach of any of its warranties or obligations under this
         agreement.

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ANUTECH/Praxis                    Page 13 of 13

<PAGE>


         (b)   It shall be a term of any  sub-licence  granted  by Praxis to any
               sublease  that the sublease  agrees to the same extent and in the
               same  terms  as the  indemnities  contained  in  CLAUSE  13.1  to
               indemnify  the  Indemnified  Parties  and that  the  Sub-Licensee
               specifically  agrees that it will not  challenge  the standing of
               the Indemnified  Parties in the event of the Indemnified  Parties
               seeking to rely upon such indemnification.

13.2     INDEMNITY BY ANUTECH

         Anutech  agrees to indemnify  Praxis  against and hold Praxis  harmless
         from any and all  loss,  liability,  damage,  claim,  cost and  expense
         (including without limitation, reasonable attorney's fees) arising from
         or in connection with a breach by the Indemnifed  parties of any of its
         warranties or obligations  under this  agreement  provided that Anutech
         shall not be required  to  indemnify  Praxis with  respect to any loss,
         liability, damage, claim, cost or expense to the extent it results from
         Praxis'   negligence  or  breach  of  any  of  Praxis'   warranties  or
         obligations under this agreement.

13.3     NOTIFICATION REGARDING INDEMNITY

         Any person  seeking  indemnity  pursuant  to CLAUSE  13.1 or 13.2 shall
         promptly notify the relevant party of any claims or suits for which the
         first  person  may  assert  indemnification  from that  party and shall
         permit that party and its insurer at the person's  expense to assume or
         participate  in the  defence of any such claims or suits and the person
         shall  co-operate  with  the  relevant  party or its  insurers  in such
         defence when reasonably requested to do so.

13.4     INSURANCE

         a)    Not less than 3 months prior to the  commencement of Marketing of
               any Product,  Praxis shall at its own cost forthwith take out and
               maintain  during  the  balance  of the Term one or more  adequate
               policies  of  insurance  for the  purposes  of product  liability
               protection in respect of activities in respect of the Products in
               the Territory for an amount not less $10,000,000.

         b)    Praxis shall provide Anutech with at least 30 days written notice
               prior to any  cancellation of a policy referred to CLAUSE 13.4(A)
               and, upon request shall furnish Anutech with a certificate of its
               insurer confirming the status of a policy taken out by Praxis.

         c)    Praxis shall procure that all of its Sub-Licensees shall maintain
               adequate product liability and third party liability insurance in
               respect  of  their   activities   pursuant  to  their  respective
               sub-licences.

14.      TERM

         Subject  to CLAUSE 15, the term of this  agreement  the rights  granted
         hereunder shall continue for the life of the Licensed  Patents,  unless
         otherwise  earlier  terminated  pursuant to CLAUSE 6  (Exploitation  of
         Licensed Patents) or CLAUSE 15 (Termination) or extended by the written
         agreement of the parties.

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ANUTECH/Praxis                    Page 14 of 14

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15.      TERMINATION

15.1     TERMINATION FOR BREACH

         Subject to CLAUSE 15.5,  if one party  breaches any term,  provision or
         obligation of this  agreement or the Research  Funding  Agreement  (the
         "DEFAULTING PARTY") and the Defaulting Party fails to:

         a)    remedy  such breach  within 90 days after  receipt of notice from
               the other party requiring remedy of the breach;

         b)    if the breach  cannot be remedied  within the said 90 day period,
               commence  action  within  the said 90 day  period to  remedy  the
               breach and  undertake  in writing to the other  party to complete
               remedy of the breach as soon as practicable thereafter; or

         c)    if the breach is incapable  of remedy,  offer to pay to the other
               party  reasonable  pecuniary  compensation  to the other party in
               respect of the loss suffered by it as a result of the breach,

         the other  party  shall  have the  right to  terminate  this  agreement
         immediately  upon  the  expiration  of the  said  period  of 90 days by
         written notice to the Defaulting Party.

15.2     TERMINATION IN DEFAULT OF PAYMENT

         Subject to CLAUSE 15.5 and notwithstanding anything contained in CLAUSE
         20, this  agreement  may be forthwith  terminated  by a party by giving
         notice to the other party if that other  party  defaults in the payment
         of any money due by that  other  party to the first  party  under  this
         agreement  and such  default  continues  for a period of 30 days  after
         notice has been given to the other party  demanding the payment of such
         money.

15.3     TERMINATION FOR INSOLVENCY

         Subject to CLAUSE 15.5 and notwithstanding anything contained in CLAUSE
         15.1,  this agreement may be terminated by a party giving notice to the
         other  party  upon the  happening  of any of the  following  events  in
         respect of that other party:

         a)    the  expiration  of four  weeks  from the  other  party  having a
               receiver,  manager,  receiver and manager or agent in  possession
               validly  appointed for the whole or any  substantial  part of its
               assets or from a court order being  validly  made for the winding
               up  of  the  other   party   other   than  for  the   purpose  of
               reorganisation or reconstruction;

         b)    immediately  a resolution of the other  party's  shareholders  is
               passed  for the  winding  up of that  party  other  than  for the
               purpose of reorganisation or reconstruction;

         c)    in the event that the other party files a petition in  bankruptcy
               or  similar  proceedings  or  is  adjudicated  bankrupt  or  if a
               petition for  bankruptcy or similar  proceedings is filed against
               the other party and is not stayed or discharged within 45 days of
               such  filing  or if the  party  becomes  insolvent  or  makes  an
               assignment  for the  benefit  of  creditors  or  enters  into any
               agreement,  arrangement or composition pursuant to bankruptcy law
               or otherwise  acknowledges  insolvency or is adjudged bankrupt or
               if the other party discontinues business;

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ANUTECH/Praxis                    Page 15 of 15

<PAGE>


         d)    any distress,  execution,  attachment or other process is made or
               levied  against  any  asset of the  other  party for an amount in
               excess of $100,000.00 and remains  outstanding or unsatisfied for
               a period of 60 days; and

e) the other  party is in  breach of an  undertaking  given  pursuant  to CLAUSE
15.1(B).

15.4     RECONSTRUCTION EXCEPTION

         A winding up or  liquidation  for the  purposes  of  reconstruction  or
         amalgamation  by the other  party shall not be an event  permitting  or
         giving rise to termination if after that reconstruction or amalgamation
         the resulting  corporation becomes bound by the terms of this Agreement
         by way of assignment or novation.

15.5     TERMINATION TO BE WITHOUT PREJUDICE

         Any  termination  of this agreement  shall be without  prejudice to the
         rights which a party has against the other in respect of anything  done
         or omitted to be done hereunder prior to such termination or in respect
         of any sums or other claims outstanding at the time of termination.

15.6     PRAXIS CHOOSES NOT TO EXPLOIT THE ANU INTELLECTUAL PROPERTY

         The parties agree to the following:

         a)    if Praxis reports to Anutech,  or Anutech  reasonably  considers,
               that Praxis has not  Exploited the ANU  Intellectual  Property in
               accordance  with  this  Agreement,  either  generally  or in some
               particular  respect,  Praxis and  Anutech  will meet and  conduct
               discussions in good faith with a view to agreeing a mechanism for
               making the ANU  Intellectual  Property  available  to Anutech for
               further  development and  Exploitation,  either by Anutech on its
               own or with or through other parties;

         b)    without  limiting  the ways that Praxis and  Anutech  might agree
               that the ANU  Intellectual  Property are to be made  available to
               Anutech,  examples  include an assignment and a licence  (whether
               exclusive or non-exclusive);

         c)    where  it is  agreed  between  Praxis  and  Anutech  that the ANU
               Intellectual  Property are to be made  available to Anutech under
               this arrangement,  Praxis and Anutech will seek to agree a method
               for  compensating  Praxis to the extent that  Praxis'  activities
               pursuant to this  agreement  produced or funded the production of
               the ANU Intellectual Property and are likely to contribute to any
               anticipated Exploitation;

         d)    without  limiting  the ways that Praxis and  Anutech  might agree
               that Praxis is to be compensated,  the compensation ought to take
               account of the parties'  respective  contributions,  receipts and
               risks which have been or are to be made or taken  before,  during
               and after the date of proposed transition; and

         e)    non  agreement  in  relation  to  the  Exploitation  of  the  ANU
               Intellectual  Property or the method of compensating the Licensee
               shall  not  in  any  way  affect  the  Licensee's  right  to  the
               Improvements.

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ANUTECH/Praxis                    Page 16 of 16

<PAGE>


16.      OBLIGATIONS AND RIGHTS ON TERMINATION

16.1     OBLIGATIONS OF PRAXIS

         Immediately  upon  termination or expiration of this agreement,  Praxis
shall:

         a)    pay all  outstanding  balances due under this agreement up to the
               date of termination;

         b)    remove  all  signs,  advertising  displays,  labels  and the like
               identifying Praxis as a licensee of the ANU Intellectual Property
               ; and

         c)    at Anutech's option and request to terminate or assign to Anutech
               any sub-licence granted by Praxis hereunder.

16.2     OBLIGATIONS OF ANUTECH

         Immediately upon  termination or expiration of this agreement,  Anutech
shall:

         a)    as soon as conveniently  possible reconcile all accounts relating
               to Praxis; and

         b)    accept  all   outstanding   balances  within  existing  terms  of
               settlement.

17.      WARRANTIES

17.1     GENERAL WARRANTIES

         Each party represents and warrants to the other that:

         a)    it has all necessary powers and authorisations necessary to enter
               into this  agreement  and observe its  obligations  hereunder and
               allow this agreement to be enforced against it;

         b)    this  agreement  does  not  contravene  any  law,  regulation  or
               official directive or any obligations or undertakings by which it
               or any of its  assets  are  bound  or cause a  limitation  on its
               powers to be exceeded;

         c)    there does not  presently  exist any event which would either now
               or with  the  effluxion  of  time  entitle  the  other  party  to
               terminate this agreement pursuant to CLAUSE 15.3;

         d)    it is  not a  party  to  any  pending  or  threatened  action  or
               proceeding  affecting  it or any of its  assets  before  a court,
               governmental  agency,  commission or arbitrator  where an adverse
               outcome could reasonably be expected to adversely impact upon the
               performance of its obligations under this agreement; and

         e)    it has no immunity from the jurisdiction of a court or from legal
               process (whether  through service of notice,  attachment prior to
               judgment,   attachment   in  aid  of   execution,   execution  or
               otherwise).

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ANUTECH/Praxis                    Page 17 of 17

<PAGE>


17.2     SPECIFIC WARRANTIES IN RESPECT OF  ANU INTELLECTUAL PROPERTY

         Anutech  warrants  and  covenants  that in respect of ANU  Intellectual
Property either:

         a)    ANU is the sole legal and beneficial owner; or

         b)    ANU has such  rights to the ANU  Intellectual  Property,  as will
               enable ANUTECH to perform its obligations under this Agreement.

         Anutech  makes no  warranty as to whether  the US Patent  5520926  (and
         corresponding  international  patents or  applications)  in the name of
         British   Technology  Group  Limited  infringes  the  ANU  Intellectual
         Property.  Anutech  makes no  representations  or  warranties as to the
         accuracy or completeness of ANU Intellectual Property.Due diligence

17.3     Praxis  warrants that it has undertaken a due diligence  examination of
         the ANU Intellectual  Property and warrants that it satisfied itself as
         to ANU's rights to and the validity of the ANU  Intellectual  Property,
         in particular the patents and patent  applications  set out in Schedule
         1.

18.      PROTECTION OF LICENSED PATENTS

18.1     MAINTENANCE OF THE LICENSED PATENTS

With respect to the existing ANU Intellectual Property and patent applications:

         a)    Anutech  will  prosecute  and  maintain  the  patents  and patent
               applications  with the  relevant  patent  offices and Praxis will
               provide all reasonable assistance requested by Anutech at Praxisi
               expense;

         b)    Praxis  shall  reimburse  Anutech  for  one  third  of any  costs
               incurred in filing, maintaining and renewing the Licensed Patents
               and patent  applications  whether  incurred  before and after the
               date of this Agreement; and

         c)    Praxis may recommend  the countries in which patent  applications
               are to be filed in the name of the ANU.

18.2     INFRINGEMENTS

         (a)   A party shall promptly report to the other in writing particulars
               of any action or activity of which the first party  becomes aware
               which might reasonably  amount to infringement of or challenge to
               any of the ANU  Intellectual  Property.

         (b)   In the event of any patent, the subject of this Agreement,  being
               infringed Praxis may at its own cost and in its own name litigate
               such infringement and may settle or compromise such litigation in
               such a manner as Praxis  shall  determine  provided  that  Praxis
               shall  consult  with  Anutech in good faith in  relation to those
               proceedings.

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ANUTECH/Praxis                    Page 18 of 18

<PAGE>

18.3     ENFORCEMENT

         (a)   In the event that  litigation  is taken or  threatened by a third
               party against any rights  associated with any patents the subject
               of this  Agreement,  the parties  shall consult in good faith and
               use their best  endeavours  mutually to  determine  the manner in
               which these proceedings are to be defended or resisted and to act
               accordingly provided always that the parties shall first seek the
               opinion of counsel experienced in such matters.

         (b)   In any litigation,  Anutech shall cooperate with Praxis in making
               available all relevant records, papers,  information and the like
               which may be relevant and in its possession.

18.4     LICENSEE'S PROCEEDINGS

         Upon the  commencement of proceedings by Praxis and during the pendency
thereof:

         a)    Praxis shall continue to make royalty reports to Anutech pursuant
               to CLAUSE  4.1 but shall  accrue  and shall not be obliged to pay
               royalties  on sale of Products in any and all  countries in which
               the infringement or challenge is occurring (other than in respect
               to sales  made  prior to the  date of  first  infringement  which
               otherwise attracted a royalty obligation which has not previously
               been  satisfied)   until  the  successful   termination  of  such
               proceedings or cessation of the  infringement or challenge occurs
               Praxis must pay any royalties  retained  under this clause into a
               separate bank account on trust for Praxis and Anutech;

         b)    Anutech shall furnish to Praxis,  upon the request of Praxis, all
               evidence and information in its possession and control pertaining
               to any such  proceedings  and  Anutech  shall  join  therein on a
               non-controlling  basis to the extent requested by Praxis.  If the
               furnishing of evidence and  information as aforesaid is likely to
               involve  Anutech in any material  expense  Praxis will enter into
               negotiations  in good faith with a view to reaching a  reasonable
               agreement as to the extent to which Anutech  should be reimbursed
               therefor;

         c)    if Praxis receives a Final Judgment holding all applicable claims
               of Licensed Patents being infringed invalid, or holding adversely
               as to  inventorship  of such Licensed  Patents or construing  all
               applicable  claims of such Licensed Patents so as not to apply to
               Products for which  royalties  have been accrued by Praxis,  then
               all moneys  withheld  under CLAUSE  18.5(A) may be paid to Praxis
               for its own benefit  absolutely  otherwise  Praxis  shall pay the
               same to Anutech  forthwith  upon receipt of Final  Judgment (less
               any amounts Praxis is entitled to deduct under CLAUSE 18.5(E);

         d)    upon  any  successful   completion  such  proceedings,   or  upon
               cessation of such  infringement or challenge,  the amounts of any
               judgment or settlement of past infringement or challenge actually
               paid to Praxis shall be firstly  applied to reimburse  Praxis for
               its costs and expenses in prosecuting  such  proceedings  and the
               balance,  if any,  shall  subject  to amount  which may be due to
               Anutech be retained by Praxis; and

         e)    if the amount of any such judgment or settlement is  insufficient
               to  cover  Praxis'  costs  and  expenses  in   prosecuting   such
               proceedings,  then the  costs  and  expenses  of  Praxis,  or the
               remainder  thereof  (as the case may be)  will be  reimbursed  to
               Praxis out of payments  withheld  pursuant to CLAUSE 18.5(A) and,
               if necessary,  out of any

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ANUTECH/Praxis                    Page 19 of 19

<PAGE>


               and all future  royalty  payments  which would  otherwise  become
               payable by Praxis to Anutech in respect to sales of  Products  in
               any country referred to in CLAUSE 18.5(A).

19.      INFRINGEMENT OF OTHERS RIGHTS

         If a legal action is commenced against Praxis alleging that any Product
         manufactured   sold   exercised  or  used  by  Praxis  or  any  of  its
         Sub-Licensees  or any  method  of  manufacture  of same or use  thereof
         infringes claims of an unexpired  patent,  patent  application or other
         intellectual  property  right  owned  by a third  party,  Praxis  shall
         promptly notify Anutech of the  commencement of legal action.  Anutech,
         in its sole  discretion,  may  choose  to defend  and/or  assist in the
         defence  of  such  litigation  but  shall  not be  obligated  to do so.
         However,  Anutech  shall (at the  expense  of  Praxis)  assist  Praxis'
         efforts to settle and/or defend such claims. If Anutech does not choose
         to  defend  such an  action,  Praxis  shall  bear all its own costs and
         expenses  and shall be  responsible  for awards  against it only to the
         extent that  indemnification,  warranties  and other  claims may not be
         available  against Anutech.  If any amounts are recovered by or awarded
         or paid to  Praxis  from or by a third  party as a  result  of any such
         action or litigation,  Praxis shall from such amounts reimburse Anutech
         for all costs and  amounts  paid by  Anutech  in  connection  with such
         action or  litigation  and  shall,  after  deducting  the  legal  costs
         incurred  by it in taking  such legal or other  action,  pay to Anutech
         from  any  compensation  recovered  thereby,   Anutech's  part  thereof
         determined in accordance  with the respective  interests of the parties
         in such compensation.

20.      CONSTRUCTION OF PATENTS

         If, in any proceedings in which the validity,  infringement or priority
         of any claim of any patent or patent  application  included in Licensed
         Patents is in issue,  a Final  Judgment is obtained,  the  construction
         placed upon any such claim by such a final judgment shall be thereafter
         followed  not only as to such  claim but as to all claims to which such
         construction applies with respect to acts occurring thereafter.

21.      WITHHOLDING TAXES

         If Praxis is  legally  obliged to deduct or  withhold  any tax from any
         payment,  in  particular  any  royalty  payment,  to be made to Anutech
         hereunder,  Praxis shall on request  provide  Anutech with receipts and
         any other  evidence  from  relevant  revenue  authorities  which may be
         required by Anutech  for its own tax  affairs  and Praxis  shall not be
         required to gross up any such amount.

22.      ASSIGNMENT

         A party  shall  not  assign  any  rights  hereunder  to third  parties,
         provided  that Anutech  shall not withhold its consent to an assignment
         by Praxis if:

         a)    the assignment is to:

          i)        a Related Corporation of Praxis; or

          ii)       a person who is  reasonably  acceptable  to  Anutech  having
                    regard  to  the  government  policy  to  which  it or ANU is
                    subject; and

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ANUTECH/Praxis                    Page 20 of 20

<PAGE>


         b)    the assignment  binds assignee to perform,  in favour of Anutech,
               each and everyone of the obligations of Praxis.

23.      NOTICES

23.1     FORM OF NOTICE

         Any notice,  approval,  consent or other communication  ("NOTICE") from
         one party to another  ("RECIPIENT") must be in writing and be signed by
         a person duly authorised by the person giving the notice.

23.2     MANNER OF SERVICE

         A notice must be served by:-

         a)    leaving it at the Recipient's address;

         b)    sending it by ordinary  pre-paid post (airmail if being sent from
               or to a place outside of Australia) to the  Recipient's  address;
               or

         c)    sending it by facsimile to the facsimile number of the Recipient.

23.3     ADDRESS FOR SERVICE

         Until  other  details  are  specified  by a  Party  as its  address  or
         facsimile number for service the following shall apply:-

         ANUTECH

         Address :         Corner Barry Drive and Daley Roads,
                           Australian Capital Territory, Australia 2601

         Postal Address :           GPO Box 4
                                    Canberra ACT 2601

         Facsimile :                6257 1433

         Attention :                Dr Chris Scott


         PRAXIS

         Address :

         Postal Address :

         Facsimile :

         Attention :

23.4     TIME OF SERVICE

         A letter or facsimile shall be taken to be served:-

         a)    in the case of a delivered letter, on the day of delivery, unless
               delivery  is made on a non  Business  Day or after 4:30 p.m. on a
               Business Day, in which case it shall be taken to be served on the
               next Business Day;

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ANUTECH/Praxis                    Page 21 of 21

<PAGE>


         b)    in the case of a posted  letter,  on the third (or seventh in the
               case of airmail) Business Day after posting; and

         c)    in the case of a  facsimile,  on receipt by the party  giving the
               notice of a transmission  confirmation report,  unless within one
               Business  Day of receipt the  Recipient  has  informed  the party
               giving  the  notice  that  the  transmission  was  incomplete  or
               garbled,  provided that in any case if  transmission is completed
               after  4:30  p.m.  (local  time in the  place of  receipt)  or is
               received on a non  Business  Day, the notice shall be taken to be
               served on the next Business Day.

24.      FORCE MAJEURE

         No party shall be responsible or liable to the any other party for, nor
         shall  this  agreement  be  terminated  as a result of any  failure  to
         perform any of its obligations hereunder (with the exception of payment
         of monies due and owing),  if such failure  results from  circumstances
         beyond  the  control  of such  party,  including,  without  limitation,
         requisition by any  government  authority or the effect of any statute,
         ordinance  or  governmental  order  or  regulations,   wars,   strikes,
         lockouts,  riots, epidemic disease, act of god, civil commotion,  fire,
         earthquake,  storm,  failure of public  utilities,  common  carriers or
         suppliers,  or any other  circumstances,  whether or not similar to the
         above  causes.  The parties  shall use  reasonable  efforts to avoid or
         remove  any  such  causes  and  shall  resume  performance  under  this
         agreement as soon as feasible whenever such cause is removed;  provided
         however that the foregoing shall not be construed to require a party to
         settle  any  labour  dispute  or to  commence,  continue  or settle any
         litigation.

25.      RESOLUTION OF DISPUTES

         a)    A party must not start arbitration or court  proceedings  (except
               proceedings seeking interlocutory relief) about a dispute arising
               out of this  agreement  ("DISPUTE")  unless it has complied  with
               this clause.

         b)    A party  claiming that a Dispute has arisen must notify the other
               party   to  the   Dispute   giving   details   of   the   Dispute
               ("NOTIFICATION").

         c)    On receipt of a  Notification  each party must refer the  Dispute
               for  resolution  by its  Chief  Executive  Officer  or the  CEO's
               nominee.

         d)    If the parties  are unable to resolve  the Dispute in  accordance
               with CLAUSE 25 the parties must use their best efforts during the
               following 7 days to agree on:

          i)        a process  to resolve  all or at least  part of the  Dispute
                    without  arbitration or court  proceedings  (eg.  mediation,
                    conciliation,  executive  appraisal  or  independent  expert
                    determination);

          ii)       the selection and payment of any person  ("MEDIATOR")  to be
                    engaged  by the  parties  for,  and the  involvement  of any
                    dispute resolution organisation in, the process;


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ANUTECH/Praxis                    Page 22 of 22

<PAGE>



          iii)      any procedural rules;

          iv)       the   timetable,   including   any   exchange   of  relevant
                    information and documents; and

          v)        the place where any meetings will be held.

         e)    The role of any  Mediator  will be to  assist  in  negotiating  a
               resolution  of the  Dispute.  A decision  of any  Mediator is not
               binding on a party unless that party has so agreed in writing.

         f)    Each party must bear its own costs of  resolving a Dispute  under
               this clause and the parties to the Dispute  must bear equally the
               costs of any Mediator  engaged and independent  premises used for
               the mediation.

         g)    If  the  Dispute  is  not  resolved  within  30  days  after  the
               Notification,  a party  that  has  complied  with  CLAUSE  25 may
               terminate the dispute  resolution process by giving notice to the
               other party to the Dispute.

         h)    If a party to a Dispute  does not comply  with any  provision  of
               CLAUSE 25 the  other  party to the  Dispute  will not be bound by
               that clause..

26.      GENERAL

26.1     GOVERNING LAW

         This  agreement  shall be construed in accordance  with and governed by
         the laws of the Australian Capital  Territory,  Australia and its form,
         execution,  validity,  construction  and effect shall be  determined in
         accordance  with the laws of the Australian  Capital  Territory and the
         parties hereby submit  themselves to the  jurisdiction of the courts in
         and of that Territory.

26.2     ENTIRE AGREEMENT

         Except  as set  out  herein,  this  agreement  constitutes  the  entire
         agreement  of the  parties  (and into  which  all  prior  negotiations,
         commitments,  representations  and  undertakings  with  respect  to the
         subject  matter are merged)  and there are no other oral  undertakings,
         warranties  or agreements  between the parties  relating to the subject
         matter of this  agreement  and this  agreement  is not  based  upon any
         representations as to profit or worth nor has any  representation  been
         made  (whether by this  agreement or  otherwise)  to induce  Anutech or
         Praxis to accept and execute this agreement.

26.3     VARIATIONS

         Any  modification,  alteration,  change  or  variation  of any  term or
         condition of this agreement shall be only made in writing,  executed by
         all parties.

26.4     SEVERABILITY

         This  Agreement is severable  and is deemed to apply  separately  as to
         each  country  comprising  the  Territory.  A  material  breach of this
         Agreement in respect of one or more  countries in the  Territory  shall
         not affect the validity or  enforceability  of this Agreement as to the
         other  countries  comprising the Territory.  If any provision  shall be
         held invalid or unenforceable, in

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ANUTECH/Praxis                    Page 23 of 23

<PAGE>


         whole  or  in  part  in  any  jurisdiction,  then  such  invalidity  or
         unenforceability  shall only affect such  provision  or part thereof in
         such jurisdiction,  and shall not in any manner affect the provision in
         this  Agreement  in  any  other  jurisdiction.  To the  extent  legally
         permissible  an arrangement  which reflects the original  intent of the
         parties  shall  be  substituted  for  such  invalid  or   unenforceable
         provision.

26.5     RELATIONSHIP OF PARTIES

         Nothing contained in this agreement shall be construed so as to operate
         or to place any party hereto in the relationship of principal employee,
         agent,  partner,  joint venturer or legal  representative  of any other
         party and it is hereby expressly  agreed and acknowledged  that each of
         the parties  hereto is an  independent  contracting  party and does not
         have the  authority or power for or on behalf of any other party hereto
         to enter into any contract,  to incur debts, to accept money, to assume
         any   obligations  or  to  make  any   warranties  or   representations
         whatsoever.

26.6     STAMP DUTY AND COSTS

         Each of the  parties  hereto  shall  bear  its own  legal  costs of and
         incidental  to the  preparation  of  this  agreement  or any  agreement
         entered or  document  executed  pursuant  to or to give  effect to this
         agreement.  Praxis  shall  pay  stamp  duty  (if any)  payable  on this
         agreement  and on any  agreement  entered  into  or  document  executed
         pursuant to or to give effect to this agreement.

26.7     ADDITIONAL DOCUMENTS

         Each party agrees that it will  forthwith upon the request of the other
         party execute and deliver all such  instruments and agreements and will
         take all such other actions as the other party may  reasonably  request
         from  time to time  in  order  to give  effect  to the  provisions  and
         purposes of this agreement.

26.8     WAIVER

         The failure of any of the  parties to insist upon a strict  performance
         of any of the terms and provisions  herein shall not be deemed a waiver
         of any  subsequent  breach or default of any of the terms or provisions
         of this agreement.

26.9     REGISTRATION OF AGREEMENT

         If this Agreement or any associated  transaction is required by the law
         of any country to be either  approved or  registered  in any country or
         with any governmental agency, Praxis shall be responsible for obtaining
         such approval or registration including without limiting the generality
         of the  foregoing,  causing the  Agreement to be stamped,  recorded and
         registered at its cost in each country  within the  Territory.  Anutech
         agrees to co-operate in any such application or registration procedure.
         Praxis shall furnish proof of compliance  with the foregoing to Anutech
         when and if Anutech so requires.

26.10    NOT OBLIGED TO ACT CONTRARY TO LAW

         No party shall be obligated to carry out or perform any of the terms of
         this agreement where such carrying out or performance  would constitute
         a violation of any treaty,  law, code or regulation of any governmental
         authority whether local,  national or  supranational.  In any event the
         other  terms of this  agreement  shall  nevertheless  continue  and the
         parties shall use all

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ANUTECH/Praxis                    Page 24 of 24

<PAGE>


         reasonable  endeavours to re-negotiate and amend this agreement so that
         the  performance  of this  agreement as so amended will not involve any
         such violation.

26.11    STATUS OF ANUTECH

         Anutech  warrants and covenants  that it enters into this  agreement as
         agent for and on behalf of ANU having  full power and  authority  so to
         do, and with the  express  consent of ANU,  to the intent that each and
         every  of the  warranties,  covenants,  terms  and  conditions  of this
         agreement are given by Anutech in its own


- --------------------------------------------------------------------------------
ANUTECH/Praxis                    Page 25 of 25

<PAGE>


    IN WITNESS:  this  Agreement  shall be duly executed and shall commence from
    the Commencement Date:-



    The COMMON SEAL of     )
    PRAXIS PHARMACEUTICALS AUSTRALIA PTY    )
    LIMITED was hereunto affixed in accordance       )
    with its constitution in the presence of:        )


    /S/ BRETT CHARLTON                      /S/ W. B. COWDEN
    Director/Secretary                      Director

    BRETT CHARLTON                          W.B. COWDEN
    Name                                    Name




    The COMMON SEAL of     )
    ANUTECH PTY LIMITED    )
    was hereunto affixed in accordance      )
    with its constitution in the presence of:        )


    /S/ T. SARTESCHI                        /S/ JOHN D. BELL
    Director/Secretary                      Director

    T. SARTESCHI
    COMPANY SECRETARY                       John D. Bell
    ANUTECH PTY LTD                         MANAGING DIRECTOR
    Name                                    Name



<PAGE>




                          SCHEDULE 1 - LICENSED PATENTS



PHOSPHOSUGAR-BASED ANTI-INFLAMMATORY AND/OR IMMUNOSUPPRESSIVE DRUGS

i        International Application No. PCT/AU89/00350
i        Inventors - William Cowden, Christopher Parish, David Willenborg
i        Priority date - 18 August 1988
i        International filing date - 18 August 1989
i        ANUTECH reference 140

COUNTRY           APPLICATION NO.   PATENT NO.       STATUS
Australia         41875/89       627500   granted
Europe   89909685.3        0429522        granted
Japan    509079/89                  examination requested
USA      988001   5506210* granted
USA-continuation           discontinued

* date of grant = 9 April 1996


NOVEL    PHOSPHOSUGARS    AND    PHOSPHOSUGAR-CONTAINING     COMPOUNDS    HAVING
ANTIINFLAMMATORY ACTIVITY

i        Inventors - William Cowden, Christopher Parish, David Willenborg
i        Priority date - 18 October 1996
i        ANUTECH reference 278

COUNTRY           APPLICATION NO.   PATENT NO.       STATUS
Australia         PO3098/96         INT              on 18 October 1997
Australia         41866/97                           examination requested
USA               08/953305                          examination requested




<PAGE>





<PAGE>




                                  EXHIBIT 10.3

                LICENCE AGREEMENT DATED OCTOBER 14, 1999 BETWEEN
                ANUTECH PTY LTD. AND PRAXIS PHARMACEUTICALS INC.


<PAGE>
                            PRAXIS PHARMACEUTICALS INC.



                                        and



                                ANUTECH PTY LIMITED







                         ----------------------------------

                                 LICENCE AGREEMENT

                         ----------------------------------









                                                     PRAXIS Pharmaceuticals Inc.
                                                                    GPO Box 1978
                                                              Canberra, ACT 2601
                                                                       Australia
                                                             Tel: (02) 6249 2939
                                                             Fax: (02) 6279 9758



<PAGE>


                                TABLE OF CONTENTS



1.    DEFINITIONS AND INTERPRETATION.......................................1

2.    GRANT OF LICENCE.....................................................4

3.    LICENCE CONSIDERATION................................................4

4.    LICENCE TERM.........................................................4

5.    PERFORMANCE OF PRAXIS................................................4

6.    RIGHT TO SUBLICENSE..................................................5

7.    GST..................................................................5

8.    OWNERSHIP............................................................6

9.    PROTECTION OF PATENTS................................................6

10.   INFRINGEMENT AND ENFORCEMENT OF PATENTS..............................7

11.   REPORTS, PAYMENTS AND ACCOUNTING.....................................7

12.   CONFIDENTIALITY......................................................8

13.   PUBLICATION..........................................................9

14.   USE OF NAME..........................................................9

15.   INDEMNITY AND INSURANCE..............................................9

16.   WARRANTIES..........................................................10

17.   ASSIGNMENT, TRANSFER................................................11

18.   TERMINATION.........................................................11

19.   MISCELLANEOUS PROVISIONS............................................12

20.   TERMINATION OF LICENCE AND RESEARCH & DEVELOPMENT AGREEMENT.........15

21.   SCHEDULE 1 - ANU Intellectual Property..............................17



- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                   Praxis Pharmaceuticals Inc

<PAGE>

THIS AGREEMENT IS MADE ON THE 14TH DAY OF OCTOBER 1999

BETWEEN:

          ANUTECH PTY  LIMITED,  ACN 008 548 650 with its  registered  office at
          ANUTECH  Court,  Cnr Barry  Drive and Daley  Road,  Acton,  Australian
          Capital Territory, Australia 2601 ("ANUTECH").


 AND:PRAXIS PHARMACEUTICALS INC., a company incorporated in Utah with its office
          at Suite 600, 595 Hornby Street, Vancouver, BC, Canada ("Praxis").

RECITALS:

A.      Praxis was incorporated on 20 June 1997 with the intention that it raise
        capital,  acquire  intellectual  property  and  research,   develop  and
        commercialise pharmaceuticals.

B.      ANU possesses  intellectual  property in the area of  phosphosugars  and
        their analogues as anti-inflammatory agents.

C.      Praxis  wishes to  license  the ANU  intellectual  property  in order to
        undertake further research and development and  commercialisation of the
        intellectual property.

D.      In accordance with the terms and conditions set forth in this agreement,
        ANUTECH  is  willing  to grant  such a licence  to Praxis  with its term
        dependant on Praxis achieving research and commercialisation milestones.

E.      ANUTECH is the commercial  subsidiary of the ANU and regularly  provides
        services to its clients by engaging the services of the ANU.

IT IS AGREED AS FOLLOWS:


DEFINITIONS AND INTERPRETATION

1.1     In this  Agreement,  unless  there is  something  inconsistent  with the
        context,  the following terms and  expressions  shall have the following
        meanings:

        "AFFILIATE"  means, in relation to a person, the person's related bodies
        corporate (within the meaning of the Corporations Law), entities who are
        partners or joint  venturers  of or trustees for the person or with whom
        the person is acting in concert and the directors  agents,  officers and
        employees  of the person or any of those  related  bodies  corporate  or
        entities.

        "ANU INTELLECTUAL  PROPERTY" means the following  intellectual  property
        owned by the ANU:

        (a) Intellectual   Property  in  relation  to  phosphosugars  and  their
            anti-inflammatory activity; and

        (b) the patents and patent applications set out in Schedule 1, including
            all  divisions,  continuations,   continuations-in-part,   renewals,
            extensions and additions thereof.

        "COMMENCEMENT DATE" means the           day of            1999.

        "CONFIDENTIAL  INFORMATION" means any information whether written, oral,
        electronic  or in any other  form which is  disclosed  by a party or its
        representatives, is claimed as

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                   Praxis Pharmaceuticals Inc

<PAGE>

        confidential  to  itself  and  which  relates  to the  ANU  Intellectual
        Property,  Research,  Results,  Products,  Agreement and business of the
        parties.  It includes all copies and notes generated from the disclosure
        but does not include information which:

       (a)  is in the public domain at the time of disclosure;

       (b)  becomes a part of the public domain after disclosure, otherwise than
            as a result of any unauthorised activity and/or omission on the part
            of the recipient;

       (c)  the recipient can prove is already in its own possession at the time
            of  disclosure  and which  was not  acquired  from the  other  party
            directly or indirectly;

       (d)  is  rightfully  acquired  from a third  party who did not  obtain it
            under an obligation of confidentiality; or

       (e)  is legally  required to be  disclosed  - the party  required to make
            disclosure  shall  notify  the other to allow  that  party to assert
            whatever exclusions are available.

        "DOLLAR",  "DOLLAR" OR "$" means  Australian  dollars  unless  otherwise
        indicated.

        "FIELD" means the use of phosphosugars as neutriceuticals, complementary
        medicines or cosmetics for the treatment of any applicable condition and
        expressly excludes:

        (a) the use of phosphosugars as ethical therapeutics; and

        (b) topical    application    for   wound   care;   and

        (c) use of fructose-1,6-diphosphate, administered non-topically, for the
            treatment or  prophylaxis  of ischaemic  disorders in humans,  which
            includes transplantation and immunosuppression.

        "GST"  means a tax on goods and  services  as  defined  by  Commonwealth
        legislation.

        "INTELLECTUAL  PROPERTY" shall mean all intellectual property rights and
        includes:

        (a) Trade Marks:  means any trade mark or trade name whether  registered
            or not  under,  or by  reference  to which,  a product or service is
            known;

        (b) Patents:  meaning any patents or patent  applications  including all
            divisions,  continuations,   renewals,  extensions  and  patents  of
            addition  thereof  which  have been or are in the  future  filed and
            granted as a patent;

        (c) Copyright subsisting in any form or manner whether written or stored
            in any form (whether  visible or not) including  without  limitation
            brochures,  design logos,  insignia,  computer  programs,  software,
            firmware and hardware;

        (d) Designs (whether or not registered); and

        (e) Know-How: meaning the unpatented, technical information,  processes,
            formulae,  technical  and  technological   documentation,   reports,
            computer programs, biological materials,  procedures or methods, all
            current and accumulated knowledge, skills and experience.

        "NET SALES" means:

        (a) for an arms  length  sale of any  Product  means  the  gross  amount
            invoiced by Praxis, or its Affiliates less the following:

               (i)  transport and insurance related charges actually allowed and
                    taken;

               (ii) trade,  quantity  or  cash  discounts  or  rebates  actually
                    allowed and taken;

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                   Praxis Pharmaceuticals Inc

<PAGE>

               (iii)credits  or  allowances  given or made on  account  of price
                    adjustments,  recalls or destruction requested or made by an
                    appropriate government agency; and

               (iv) any tax (excluding  income tax),  excise or other government
                    charge  upon  or  measured  by  the  sale,   transportation,
                    delivery or use of the Product which is actually incurred by
                    the seller.

        (b)    for a non-arms length sale,  means the highest of the most recent
               Net Sales at which  Praxis,  its  Affiliates,  its  subsidiaries,
               joint venturers  licensees or agents has sold similar  quantities
               of Products in an arms length sale.

        "PRODUCTS"  means any  matter,  article or thing which  incorporates  or
        arises  from the whole or partial  use of ANU  Intellectual  Property or
        Results.

        "RESULTS"  means  all  Intellectual   Property,   materials   (including
        substances,   compounds,  biological  material,  products,  samples  and
        devices)  in whatever  form and  information  however  known or recorded
        (including trade secrets, processes,  techniques,  designs, plans, data,
        test results,  findings,  evaluations and reports) generated as a result
        of any  exploitation  of or in any  connection  with  any  research  and
        development conducted at the ANU within the Field.

        "SUBLICENSE  FEES"  means all  payments to Praxis in  consideration  for
        rights to the ANU Intellectual  Property,  Results and Products pursuant
        to a sublicence,  assignment, joint venture, strategic alliance or other
        arrangement.

        Sublicence Fees shall not include:

        (a) fees for research and development undertaken by Praxis including for
            example preclinical research and clinical studies; nor

        (b) the royalty  percentage  above that is required to be paid by Praxis
            pursuant to clause 3 (License Consideration).

1.2 In this Agreement unless the contrary intention appears:


        (a) a reference to a clause, schedule, attachment,  annexure or appendix
            is a reference to a clause of or schedule,  attachment,  annexure or
            appendix to this Agreement and references to this Agreement  include
            any recital, schedule annexure, attachment, or appendix;

        (b) a reference  to this  Agreement or another  instrument  includes any
            variation or replacement of either of them;

        (c) a  reference  to a statute,  ordinance,  code or other law  includes
            regulations  and  other  instruments  under  it and  consolidations,
            amendments, re-enactments or replacements of any of them;

        (d) the singular includes the plural and vice versa;

        (e) if a period of time is  specified  and dates from a given day or the
            day of an act or event,  it is to be  calculated  exclusive  of that
            day;

        (f) if an event must occur on a  stipulated  day which is not a business
            day, then the  stipulated  day will be taken to be the next business
            day;

        (g) headings  are  inserted  for  convenience  and  do  not  affect  the
            interpretation of this Agreement;

        (h) words  importing  any one gender  shall mean and include  masculine,
            feminine and/or neuter where appropriate;

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

        (i) words importing  natural persons shall (where  appropriate) mean and
            include corporations and unincorporated associations and vice versa;

        (j) schedules and attachments  form part of and are incorporated in this
            Agreement.

        (k) no provision  of this  Agreement  will be  construed  adversely to a
            party  solely on the ground that the party was  responsible  for the
            preparation of this agreement or that provision; and

        (l) an  expression  importing a natural  person  includes  any  company,
            partnership,  joint venture, association,  corporation or other body
            corporate and any government, governmental, administrative, judicial
            or semi-governmental agency or body.


1.3     For the  avoidance  of doubt the recitals to this  Agreement  shall form
        part of this Agreement and in the event of any inconsistency between the
        recitals and the other provisions of this Agreement the other provisions
        of this Agreement shall prevail.


GRANT OF LICENCE

1.4     ANUTECH  grants to Praxis an  exclusive,  worldwide  licence  to use and
        exploit the ANU  Intellectual  Property  and  Results  within the Field,
        including  the  right to  sublicense  pursuant  to  clause  6 (Right  to
        Sublicense).


LICENCE CONSIDERATION

1.5   In consideration for the grant of the licence Praxis will pay to ANUTECH:

        a)  a 4% royalty on Net Sales of Products by Praxis;

        b)  50% of all  royalty  income on Net Sales of Products  received  from
            sublicensees;

        c)  15% of all  Sublicence  Fees.

        d)  ANUTECH  shall  maintain the right to hold 300,000  shares issued to
            ANUTECH 31 March  1999.  These  shares  will be held in escrow for a
            period of 12 months from the date of issue.

1.6     The obligation in clause 3.1 survives the  termination of the licence in
        clause 2.1 or this Agreement.


LICENCE TERM

1.7     The Licence in clause 2.1 commences upon the Commencement  Date and ends
        on the  expiration of the last to expire of the patents  covered by this
        Agreement,  unless  otherwise  earlier  terminated  pursuant to clause 5
        (Performance of Praxis) or clause 18 (Termination).


PERFORMANCE OF PRAXIS

1.8     If Praxis  fails to comply with the  following  performance  milestones,
        ANUTECH has at its  election the right to  terminate  this  Agreement in
        accordance with clause 18(Termination).

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.9   Commercialisation milestones

        a)  Praxis shall use best efforts to commercialise  the ANU Intellectual
            Property and Results by undertaking an ongoing and active  research,
            developmental,   manufacturing,   marketing,  licensing  or  capital
            raising program, as appropriate, directed toward the exploitation of
            the ANU Intellectual  Property and Results within the Field.

        b)  Part of these best efforts  includes Praxis  providing to ANUTECH as
            soon as  practicable  a business  plan (and any updates  thereafter)
            which addresses Praxis's  capacities,  objectives and strategies for
            such a  commercialisation  program.

        c)  Praxis shall also provide  ANUTECH with an annual written report (on
            the anniversary of the  Commencement  Date) on its progress  towards
            achieving these commercialisation milestones.


RIGHT TO SUBLICENSE

1.10    ANUTECH  grants  to  Praxis  the right to  sublicence  ANU  Intellectual
        Property and Results within the Field, subject to:

        a)  the  prior   written   approval  of  ANUTECH   which  shall  not  be
            unreasonably withheld;

        b)  the  sublicensee  being bound to similar  terms as contained in this
            Agreement; and

        c)  the  royalty  and  Sublicence  Fee stream  provided  for in clause 3
            (Licence Consideration) are reserved.


GST

1.11    The parties  acknowledge that this Agreement,  including all pricing and
        compensation  terms,  whether  by way  of  reimbursement,  indemnity  or
        otherwise has been drafted  without  taking into account the effect,  if
        any, of GST. The following  principles apply when determining the amount
        (including royalties) payable (the Payment) for any rights, services, or
        any other thing granted or supplied pursuant to this Agreement.


1.12    If GST is payable  in  relation  to the  granting  of rights,  supply of
        services  or any other  thing,  the  Payment  will be the  consideration
        specified herein plus GST (if any).


1.13    If the  Payment  is  determined  by  reference  to any cost,  expense or
        liability  incurred  by a party  (the  Payee),  the  reference  to cost,
        expense or liability  means the actual amount incurred by the Payee less
        the amount of any GST input tax credit the Payee is entitled to claim in
        respect of that cost, expense or liability. The Payee will be assumed to
        be entitled to claim full input tax credits unless it demonstrates  that
        its entitlement is otherwise prior to the date on which the Payment must
        be made.


1.14    If  the  Payment  is  a  reimbursement  or  indemnification  of  a  loss
        determined  (including  a percentage  of sales  revenue) by reference to
        revenue  received  and costs  incurred,  the revenue will be the revenue
        earned net of GST and the costs will be determined  in  accordance  with
        clause 7.3.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>


1.15    If a party sets off an amount  otherwise  payable under this  Agreement,
        the principles set out above shall be applied to calculate the amount to
        be set off as if that amount had been paid.


1.16    Each party  agrees to do all  things,  including  providing  invoices or
        other  documentation  containing  stipulated  information,  that  may be
        necessary  or desirable to enable or assist the other party to claim any
        credit, set off, rebate or refund in relation to any GST included in any
        payment made under this Agreement.



OWNERSHIP

1.17    The following  shall be owned by the ANU and licensed to Praxis pursuant
        to the terms of this Agreement:

        a)  improvements to ANU Intellectual Property ; and

        b)  new  patents  and patent  applications  arising  from the use of ANU
            Intellectual Property.


PROTECTION OF PATENTS

1.18    With  respect to the  existing  ANU  Intellectual  Property  patents and
        patent applications:

        a)  the parties shall  cooperate in the  prosecution  and maintenance of
            the  patents  and  patent  applications  with  the  relevant  patent
            offices;

        b)  from the  Commencement  Date, one third of any past and future costs
            and expenses incurred in their filing, maintenance and renewal shall
            be borne by Praxis;

        c)  Praxis may select the countries in which patent  applications are to
            be filed in the name of the ANU;  and

        d)  if Praxis decides not to request patent  protection for an invention
            in any  country,  ANU may file or  maintain  at its own cost  patent
            applications which Praxis has declined to file or maintain, and such
            patent  applications  or  granted  patents  shall  lie  outside  the
            provision of this Agreement.

1.19    With respect to any new patentable  inventions  arising from the Results
        and use of ANU Intellectual Property:

        a)  Praxis  may  request   ANUTECH  to  file  and   prosecute  a  patent
            application,  in ANU's name, for the invention or agree to treat the
            invention as a trade secret;

        b)  the parties shall  cooperate in the  prosecution  and maintenance of
            the  patents  and  patent  applications  with  the  relevant  patent
            offices;

        c)  all costs and expenses incurred in filing,  maintaining and renewing
            the patents  and patent  applications  shall be borne by Praxis;  d)
            Praxis may select the countries in which patent  applications are to
            be filed in the name of the ANU;  and

        e)  if Praxis decides not to request patent  protection for an invention
            in any  country,  ANU may file or  maintain  at its own cost  patent
            applications which Praxis has declined to file or maintain, and such
            patent  applications  or  granted  patents  shall  lie  outside  the
            provision of this Agreement.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

INFRINGEMENT AND ENFORCEMENT OF PATENTS

1.20  Infringement

        In the  event  of any  patent,  the  subject  of this  Agreement,  being
        infringed  Praxis may at its own cost and in its own name  litigate such
        infringement  and may settle or  compromise  such  litigation  in such a
        manner as Praxis shall determine provided that Praxis shall consult with
        ANUTECH in good faith in relation to those proceedings.

1.21  Enforcement

        In the event that  litigation  is taken or  threatened  by a third party
        against  any rights  associated  with any  patents  the  subject of this
        Agreement,  the parties  shall  consult in good faith and use their best
        endeavours  mutually to determine the manner in which these  proceedings
        are to be defended or resisted and to act  accordingly  provided  always
        that the parties shall first seek the opinion of counsel  experienced in
        such matters.

1.22    In any  litigation,  ANUTECH  shall  cooperate  with  Praxis  in  making
        available all relevant records,  papers,  information and the like which
        may be relevant and in its possession.

1.23    Nothing  herein shall  preclude  ANUTECH from  defending or pursuing any
        such actions.



REPORTS, PAYMENTS AND ACCOUNTING

1.24    Within 30 days after the first day of January,  April,  July and October
        of each  year,  Praxis  shall  provide  to  ANUTECH a true and  accurate
        royalty report. This royalty report will cover payments due under clause
        3 (Licence Consideration) and specify:

        a)  the total  quantity  of  Products  sold or provided by it and by its
            sublicensees;

        b)  the Net Sales price at which the Products were sold or provided;

        c)  the calculation of the royalty due;

        d)  the total royalties so calculated and due to ANUTECH; and

        e)  the amount of Sublicence Fees and the royalty due.

1.25    For the term of this  Agreement  and  simultaneous  with the delivery of
        each such  royalty  report,  Praxis shall pay to ANUTECH the royalty and
        any other  payments due under this  Agreement for the period  covered by
        such report.


        Praxis shall be responsible for all payments that are due to ANUTECH but
        have not been paid by Praxis' sublicensees to Praxis.

1.26    All payments hereunder by Praxis shall be payable in Australian Dollars.


1.27    During  the term of this  Agreement,  Praxis  shall  keep  complete  and
        accurate  records  of its and its  sublicensees  sales of  Products  and
        Sublicence  Fees in  sufficient  detail  to enable  compliance  with its
        obligations under this Agreement to be verified.


1.28    Praxis  shall  permit  ANUTECH  or  its  representatives,  at  ANUTECH's
        expense, to periodically  examine its books,  ledgers and records during
        business  hours and with 48 hours  notice for the  purpose of and to the
        extent  necessary to ensure that Praxis has complied,  and is complying,
        with its obligations under this Agreement.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.29    In the event that the  difference  between the amount of royalty due and
        the amount of royalty actually paid exceeds 5% then Praxis shall pay the
        amount of the underpayment plus the cost of such examination.


1.30    If Praxis  fails to pay  ANUTECH  an amount  due under  this  Agreement,
        Praxis shall upon  notification pay to ANUTECH the amount owing together
        with interest,  such interest to be at the rate applicable to overdrafts
        charged by the  Commonwealth  Bank of  Australia at the date of payment,
        calculated  daily from the due date or the date the shortfall in payment
        was  effective,  as the case may be. The payment of such interest  shall
        not  preclude  ANUTECH  from  exercising  any  other  rights it may have
        because any payment is overdue.



CONFIDENTIALITY

1.31    The parties acknowledge that the Confidential Information is valuable to
        the party in question and each party undertakes to keep the Confidential
        Information  secret and to protect and preserve the confidential  nature
        and secrecy of the Confidential Information.


1.32 The recipient of Confidential Information must:

     1.33  keep it confidential;

     1.34 use it only for the purposes of the Agreement; 1.35 not disclose it to
          any person other than:

        (a) to those of the  recipient's  employees or legal advisers who have a
            need to know and who have first been  directed  and have  undertaken
            orally or in writing to keep it confidential; or

        (b) to other people, such as contractors, visitors and agents who have a
            need to know and who have agreed in writing to keep it  confidential
            in accordance with this Agreement

     1.36 not copy it or any part of it other than as strictly necessary for the
          purposes of this Agreement and must mark any such copy "Confidential";

     1.37 promptly comply with any request by the discloser to return or destroy
          any or all copies of Confidential Information; and

     1.38 implement security practices against any unauthorised  copying, use or
          disclosure of the Confidential Information.

1.39  Each party shall take:

        a)  reasonable  efforts  to ensure  that any  person  who has  access to
            Confidential   Information  does  not  make  any  unauthorised  use,
            reproduction or disclosure of that information; and

        b)  reasonable steps to enforce the confidentiality  obligations imposed
            or required to be imposed by this  agreement,  including  diligently
            prosecuting  at its cost any  breach  or  threatened  breach of such
            confidentiality  obligations  by a person  to whom it has  disclosed
            Confidential Information and, where appropriate, making applications
            for interim or interlocutory relief.

1.40    The  provisions  of this  clause 12 shall  continue to have effect for a
        period of four (4) years after termination or expiry of this Agreement.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.41    Upon the  termination  or  expiry of this  agreement  the  recipient  of
        Confidential  Information  shall deliver (or with the discloser's  prior
        consent,  destroy  or  erase) to the  discloser  all  material  forms of
        Confidential Information in its or its representatives possession, power
        or control.  The return of  Confidential  Information  under this clause
        does  not  release  either  party or their  representatives  from  their
        confidentiality obligations under this clause.


PUBLICATION

1.42    If  ANUTECH or its  employees  or agents  wish to  publish or  otherwise
        disclose any information  contained in the ANU Intellectual  Property or
        Results,  other than in  accordance  with  clause 12  (Confidentiality),
        including by way of written  disclosure  or any oral  disclosure  at any
        seminar,  lecture  or  other  meeting  ("Publication"),   the  following
        procedures shall be observed:


        (a) ANUTECH  shall  submit  the  Publication  to Praxis 30 days prior to
            disclosure;

        (b) within the 30 day period  Praxis will  consider  whether to agree to
            the  Publication  and shall advise ANUTECH what part (if any) of the
            information it does not wish published;

        (c) if Praxis does not advise  ANUTECH  within the 30 day period that it
            objects to the  Publication  it shall be deemed to have consented to
            the Publication;

        (d) if Praxis does advise ANUTECH of its objection then the  information
            in question will not be published:

            (i) until the date upon which the complete Australian  specification
            in  relation  thereto  becomes  open  to  public  inspection  at the
            Australian Patents Office; and

            (ii) in the case of information  which is not patentable or which it
            is not  proposed  to  patent,  for so long as  further  confidential
            research  or  development  work or  potential  or actual  commercial
            exploitation  is being actively  pursued in relation  thereto but in
            any case not to exceed 2 years;

        (e) where  appropriate,  ANUTECH  will  make  proper  acknowledgment  of
            Praxis.


USE OF NAME

1.43    Any  proposed  use of a  party's  name  by the  other  in any  published
        material  (including  prospectus  information)  must be  approved by the
        other party in writing prior to release of that published material.


INDEMNITY AND INSURANCE

1.44    Praxis hereby agrees to defend, indemnify and hold harmless ANUTECH, ANU
        and  their  employees  from and  against  any and all  demands,  claims,
        liabilities, damages, costs and expenses which may be brought against or
        incurred by ANUTECH,  ANU and their  employees as a result of the use to
        which Praxis or its sublicensees make of the ANU Intellectual  Property,
        Results  and  Products  the  subject  of the  licence  granted  in  this
        Agreement,  other  than to the  extent (if any) that the same are caused
        solely  by the  gross  negligence  of  ANUTECH,  ANU or of any of  their
        employees.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

        The  indemnity  above shall also apply to actions  that may arise out of
        the capital  raising  that Praxis  undertakes  for the  purposes of this
        Agreement.

1.45    From  the date  that any  Product  arising  out of the ANU  Intellectual
        Property is first applied for human use (and for the term or foreseeable
        term of the human  use)  Praxis  undertakes  to hold  product  liability
        insurance  to the  value of at least  $5,000,000.00 .


1.46    Praxis  shall at all times  maintain  in full force and  effect  general
        liability  insurance with limits of not less than  $5,000,000.00.

1.47    Such policies shall name ANUTECH and the ANU as additional  insureds and
        shall be purchased from a reputable insurer. Certificates evidencing the
        coverage shall be provided to ANUTECH.



WARRANTIES

1.48  Right to enter Agreement


        Each Party  hereby  warrants  to the other  that it has the full  right,
        power, authority and liberty to enter into this Agreement and to perform
        all of its  respective  duties  and  obligations  hereunder.  Each party
        warrants to the other that it is not under any other duty or  obligation
        which  is  contrary  to or  inconsistent  with  any  of its  duties  and
        obligations hereunder.

1.49  No contrary agreements


        Each party hereby  warrants to the other that it will not enter into any
        agreement,  arrangement or  understanding  with any third party which is
        contrary to or inconsistent with any of that party's rights,  duties and
        obligations under this Agreement.

1.50  Status of ANUTECH


        ANUTECH  warrants and  covenants  that it enters into this  Agreement as
        agent for and on behalf of ANU having full power and authority so to do,
        and with the  express  consent of ANU, to the intent that each and every
        of the warranties, covenants, terms and conditions of this Agreement are
        given by and bind both ANUTECH in its own right and ANU.

1.51  Due diligence


        Praxis  warrants that it has  undertaken a due diligence  examination of
        the ANU  Intellectual  Property  licensed in this agreement and warrants
        that it  satisfied  itself as to ANU's rights to and the validity of the
        ANU  Intellectual   Property,  in  particular  the  patents  and  patent
        applications set out in Schedule 1.

1.52  ANU Intellectual Property


        To the best of its  knowledge  ANUTECH  warrants and  covenants  that in
        respect of ANU Intellectual Property either:

        (a) ANU is the sole legal and beneficial owner; or

        (b) ANU has such rights to the ANU Intellectual Property, as will enable
            ANUTECH to perform its obligations under this Agreement.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

        ANUTECH  makes no  warranty  as to whether  the US Patent  5520926  (and
        corresponding  international  patents  or  applications)  in the name of
        British   Technology  Group  Limited   infringes  the  ANU  Intellectual
        Property.

1.53   Results achieving purpose


        ANUTECH  makes no  representations  or  warranties as to the accuracy or
        completeness of the Results generated by ANUTECH, or their capability to
        achieve a particular purpose.

1.54  Fundamental Terms


        Each party acknowledges that the warranties  contained in this clause 16
        (Warranties) are fundamental terms of this Agreement.


ASSIGNMENT, TRANSFER

1.55    This  Agreement may not be assigned or otherwise  transferred  by Praxis
        without the prior written consent of ANUTECH. An assignment is deemed to
        include a change in greater than 50%  beneficial  ownership of shares in
        Praxis with the  exception  of such a change in share  holding in Praxis
        through capital raising.


1.56    Any  permitted  assignee  shall assume all  obligations  of its assignor
        under this Agreement.


1.57    No assignment shall relieve Praxis of responsibility for the performance
        of any accrued obligation(s) which Praxis then has hereunder.



TERMINATION

1.58    A party may terminate  this Agreement upon 30 days written notice to the
        other  party on the  occurrence  of any of the  following  by the  other
        party:

        a)  upon or after the bankruptcy,  insolvency, dissolution or winding up
            of such party (other than dissolution or winding up for the purposes
            of reconstruction or amalgamation); or

        b)  the failure of such party to comply with its obligations  under this
            agreement,  if such default is not cured (if capable of being cured)
            within  30 days of the  party not in  default  giving  notice of the
            default; or

        c)  if the  representations  and  warranties  made under this  Agreement
            prove inaccurate or false in any material respect.

1.59    Without  limiting clause 18.1 (b),  ANUTECH may terminate this Agreement
        upon 30 days written notice to Praxis in the event Praxis:

        a)  fails to make any payment which is due and payable  pursuant to this
            Agreement and such payment remains unpaid for more than 30 days; or

        b)  fails to achieve any of the  performance  milestones  in  accordance
            with clause 5 and is  demonstrated  not to be making best efforts in
            attempting to achieve these milestones and such default is not cured
            (if capable of being cured) within 90 days of ANUTECH  giving notice
            of the default.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.60    The provisions of this clause 18 and clauses 3.1 (Licence Consideration)
        12  (Confidentiality),   11  (Reports,   Payments  and  Accounting),  15
        (Indemnity  and  Insurance,   19.12  (Governing  Law)  and19.9  (Dispute
        Resolution) shall continue in full force and effect  notwithstanding the
        termination,  any  alterations  or additions to the other  provisions of
        this Agreement.

1.61    Upon  termination  of this  Agreement and except as otherwise  expressly
        provided:

        a)  any  rights  or  obligations  of a party  which  may have  arisen or
            accrued prior to termination shall not be affected;

        b)  all  licences  granted to Praxis  under the terms of this  Agreement
            shall  terminate  and Praxis  shall  cease its  exploitation  of the
            relevant  intellectual  property  other than  provided for in clause
            18.4 (d);

        c)  Praxis shall promptly pay to ANUTECH any amounts due under the terms
            of this Agreement including royalties and Sublicence Fees which have
            accrued  as of the  date of  termination;  d)  Praxis  may  sell all
            inventory  of the  Product  that it may  have on hand at the date of
            termination  provided  that it pays  royalties  as  provided in this
            Agreement.

1.62    If any party  terminates the Agreement and  sublicensees are not then in
        default  under  the  terms of  their  sublicence  agreements  hereunder,
        ANUTECH  shall  have the right  (but not the  obligation)  to assume and
        continue  sublicence  agreements with payments  thereunder being made by
        the sublicensees  directly to ANUTECH without any further obligations on
        the part of Praxis with respect thereto.

1.63    Waiver by either  party of any breach (or a  succession  of breaches) of
        any one or more of the  provisions of this  Agreement  shall not deprive
        such party of any right to  terminate  this  Agreement  pursuant  to the
        terms of this clause 18 upon the occasion of any subsequent breach.


MISCELLANEOUS PROVISIONS

1.64  Binding obligations


        The duties and  obligations  imposed and the benefits  conferred by this
        Agreement  are to be  binding  upon and to enure to the  parties  and to
        their respective successors and permitted assigns.

1.65  Other instruments


        Each  party  shall  prepare  and  execute  such  other  instruments  and
        documents  and do such  other  acts and  things as may be  necessary  or
        desirable  to ensure  each  party has such  rights and  interest  as are
        contemplated  for  it by  this  Agreement  or as  may  be  necessary  or
        desirable to give full effect to the provisions of this Agreement.

1.66  Whole Agreement


        This Agreement combines the whole  understanding of the Parties relating
        to its  subject  matter  and it  supersedes  and  cancels  any  and  all
        agreements,  understandings or commitments made by the same Parties with
        respect  to the same  subject  matter.  Any  purported  representations,
        warranties or other promises of the Parties not recorded in it are of no
        effect.

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.67  Amendment

        The  variation or waiver of a provision  of this  Agreement or a Party's
        consent  to a  departure  from a  provision  by another  Party,  will be
        ineffective unless in writing executed by the Parties.  The requirements
        concerning variation or waiver apply to this clause itself.

1.68  No waiver

        No waiver by either party of any breach (or a succession of breaches) of
        any one or more of the  provisions of this  Agreement by the other party
        shall be deemed to be a waiver of any  subsequent  breach of the same or
        any other provision.

1.69  Illegality

        If any  provision  of this  Agreement  shall  be  construed  so as to be
        illegal or invalid the legality or the  validity of any other  provision
        shall not be affected thereby.  Any legal or invalid provisions shall be
        severable  and all  other  provisions  shall  remain  in full  force and
        effect.

1.70  Notices

        A party notifying or giving notice under this Agreement must notify

        (a) in writing;

        (b) addressed  to the address of the  recipients  specified  below or as
            altered by notice given in accordance with this clause; and

        (c) delivered by hand, facsimile, registered mail or post.

       A notice shall be deemed received:

        (a) if hand delivered on the date of delivery

        (b) if sent by facsimile on  generation  of an  acknowledgment  that the
            transmission has been successfully completed,

        (c) if sent by  registered  mail on  acknowledgment  of receipt by or on
            behalf of the recipient

        (d) if dispatched by post, after 5 days including day of posting.

        If a notice is received on a day other than a business day or after 4.30
        pm on a business  day,  then it is deemed  received on the next business
        day.

        Notice addresses


        ANUTECH Pty Ltd                 Praxis Pharmaceuticals Inc.
        GPO Box 4                       GPO Box 1978
        CANBERRA  ACT 2601              Canberra  ACT 2601
        or
        ANUTECH Court
        Cnr. Barry Drive and Daley Road and
        ACTION  ACT 2601
                                        Suite 600, 595 Hornby Street, Vancouver,
        Facsimile 02 6257 1433          BC, Canada
                                        Facsimile: 1 (604)646 5649

- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

1.1   Force Majeure


        No party  shall be  responsible  or liable to any other  party for,  nor
        shall this Agreement be terminated as a result of any party's failure to
        perform any of its obligations hereunder,  with the exception of payment
        of monies due and owing,  if such  failure  results  from  circumstances
        beyond  the  control  of  such  party,  including,  without  limitation,
        requisition  by any  government  authority or the effect of any statute,
        ordinance or governmental order or regulations, wars, strikes, lockouts,
        riots, epidemic disease, act of god, civil commotion,  fire, earthquake,
        storm, failure of public utilities, common carriers or suppliers, or any
        other  circumstances,  whether or not similar to the above  causes.  The
        parties shall use reasonable  efforts to avoid or remove any such causes
        and shall resume  performance  under this  Agreement as soon as feasible
        whenever  such cause is removed;  provided  however  that the  foregoing
        shall not be construed  to require a party to settle any labour  dispute
        or to commence, continue or settle any litigation.

        If after six months the force majeure  continues,  the Parties must meet
        in good  faith to  discuss  the  situation  and  endeavour  to achieve a
        mutually satisfactory resolution of the problem.

1.2   Dispute resolution


        If a dispute  arises  between  the  Parties  out of or  relating to this
        Agreement (the "Dispute"), any Party seeking to resolve the Dispute must
        do so  strictly  in  accordance  with  the  provisions  of this  clause.
        Compliance  with this clause is a condition  precedent to seeking relief
        in any court or tribunal in respect of the Dispute.

        A Party  seeking to resolve the Dispute  must notify the  existence  and
        nature of the  Dispute to the other  Party  ("the  Notification").  Upon
        receipt of a  Notification  the  Parties  must refer  resolution  of the
        Dispute to their respective chief executive officers or their nominees.

        If the Dispute has not been resolved  within thirty (30) days of receipt
        of the  Notification  then  any  Party  may  refer  the  Dispute  to the
        Australian Commercial Dispute Centre Limited ("ACDC") for mediation. The
        parties  must  negotiate  in good  faith,  and in  accordance  with  the
        Conciliation Rules of ACDC, to resolve the Dispute.

        If the Dispute has not been resolved  within sixty (60) days of referral
        to ACDC either Party is free to initiate proceedings in a court.

1.3   Stamp Duty


        All stamp duty levied upon this agreement shall be paid by Praxis.

1.4   Costs


        Each Party  agrees to bear its own legal and other costs and expenses in
        connection  with the  preparation and execution of this Agreement and of
        other related documentation.

1.5   Governing law


        This Agreement shall be construed in accordance with and governed by the
        laws of the Australian  Capital  Territory,  Australia,  and the parties
        hereby  submit  themselves to the  jurisdiction  of the courts in and of
        that Territory.


- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>

TERMINATION OF LICENCE AND RESEARCH & DEVELOPMENT AGREEMENT

1.6     The parties entered into a Licence and Research & Development  Agreement
        dated 27 October  1997 and an Addendum  to the  Licence  and  Research &
        Development   Agreement   dated  8  October  1998   ("Licence   and  R&D
        Agreement").

1.7     The parties  have agreed to end the Licence and R&D  Agreement by mutual
        agreement with effect from the Commencement Date of this Agreement.

1.8 With effect from the Commencement Date of this Agreement:

        (a) the parties agree that the Licence and R&D Agreement is  terminated;
            and

        (b) each party  permanently  releases each other party from any actions,
            suits, causes of action,  arbitration,  debts, dues, costs,  claims,
            demands,  verdicts  and  judgments,  either  at law or in  equity or
            arising under statute ("Claims") which but for their entry into this
            termination, they or any of them have or may have against each other
            arising  from or in  connection  with the early  termination  of the
            Licence and R&D Agreement.

1.9   Each party must:

        (a) use its best efforts to do all things necessary or desirable to give
            full effect to this termination; and

        (b) refrain from doing  anything that might hinder  performance  of this
            termination.



- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc

<PAGE>


   IN WITNESS: this Agreement shall be duly executed and shall commence from the
   Commencement Date:-



   The COMMON SEAL of                             )
   PRAXIS PHARMACEUTICALS INC                     )
   was hereunto affixed in accordance             )
   with its constitution in the presence of:      )




   /S/ BRETT CHARLTON                            /S W.B. COWDEN
   Director/Secretary                            Director



   BRETT CHARLTON                                W.B. COWDEN
   Name                                          Name









   The COMMON SEAL of                             )
   ANUTECH PTY LIMITED                            )
   was hereunto affixed in accordance             )
   with its constitution in the presence of:      )






   /S/ T. SARTESCHI                              /S/ JOHN D. BELL
   Director/Secretary                            Director

   T. SARTESCHI
   COMPANY SECRETARY                             John D. Bell
   ANUTECH PTY LTD                               MANAGING DIRECTOR
   Name                                          Name














- --------------------------------------------------------------------------------
ANUTECH Pty Ltd                                       Praxis Pharmaceuticals Inc


<PAGE>




SCHEDULE 1 - ANU INTELLECTUAL PROPERTY


PHOSPHOSUGAR-BASED ANTI-INFLAMMATORY AND/OR IMMUNOSUPPRESSIVE DRUGS

o  International Application No. PCT/AU89/00350
o  Inventors - William Cowden, Christopher Parish, David Willenborg
o Priority date - 18 August 1988 o International  filing date - 18 August 1989 o
ANUTECH reference 140

COUNTRY            APPLICATION NO.    PATENT NO.         STATUS
Australia          41875/89           627500             granted
Europe             89909685.3         0429522            granted
Japan              509079/89                             request examination
USA                988001             5506210*           granted
USA-continuation   discontinued

* date of grant = 9 April 1996


NOVEL PHOSPHOSUGARS AND PHOSPHOSUGAR-CONTAINING COMPOUNDS HAVING
ANTIINFLAMMATORY ACTIVITY

o  Inventors - William Cowden, Christopher Parish, David Willenborg
o  Priority date - 18 October 1996
o  ANUTECH reference 278

COUNTRY            APPLICATION NO.    PATENT NO.         STATUS
Australia          PO3098/96
INT                                                      on 18 October 1997






                                  EXHIBIT 10.4

               SHAREHOLDER AGREEMENT DATED AS OF OCTOBER 15, 1999,
               BETWEEN PRAXIS PHARMACEUTICALS AUSTRALIA PTY LTD.,
        PRAXIS PHARMACEUTICALS INC., PERPETUAL TRUSTEES NOMINEES LIMITED,
                   AND ROTHSCHILD BIOSCIENCE MANAGERS LIMITED


<PAGE>


                      PRAXIS PHARMACEUTICALS AUSTRALIA PTY
                                     LIMITED
                                (ACN 082 811 630)

                                     - and -

                           PRAXIS PHARMACEUTICALS INC.

                                     - and -

                       PERPETUAL TRUSTEES NOMINEES LIMITED
                                (ACN 000 341 533)

                                     - and -

                     ROTHSCHILD BIOSCIENCE MANAGERS LIMITED
                                (ACN 072 515 247)











                             SHAREHOLDERS AGREEMENT












                              ARNOLD BLOCH LEIBLER
                           Solicitors and Consultants
                               333 Collins Street
                               MELBOURNE VIC 3000

                               Tel:(03) 9229 9999

                               Ref:JCS:EVK:1073464
                        (L:\SEC\EVK\1073464\PRAXSHAG.DOC)



<PAGE>


                             SHAREHOLDERS' AGREEMENT

THIS AGREEMENT is made the 15th day of October December 21, 1999

BETWEEN:

                  PRAXIS PHARMACEUTICALS AUSTRALIA PTY LIMITED (ACN 082 811 630)
                  of 60  Marcus  Clarke  Street,  Canberra,  Australian  Capital
                  Territory 2601 ("Company")

                                     - and -

               PRAXIS PHARMACEUTICALS INC. of 50 West Broadway, Salt Lake
         City, Utah, United States of America 84101 ("Praxis USA")

                                     - and -

               PERPETUAL  TRUSTEES  NOMINEES  LIMITED  (ACN  000 341  533) of 39
         Hunter Street,  Sydney,  New South Wales in its capacity as trustee for
         The Australian  Bioscience  Trust  constituted by a Trust Deed dated 20
         August 1998 ("Trustee")

                                     - and -

               ROTHSCHILD BIOSCIENCE MANAGERS LIMITED
         (ACN 072 515 247) of Level 15, 1 O'Connell Street, Sydney, New South
         Wales ("RBML")


WHEREAS:

A        The current  Shareholder is Praxis USA who is the registered  holder of
         the entire 100 Class A Shares issued.

B        It is intended that prior to the  subscription  by the Trustee,  Praxis
         USA will be the registered holder of 1,400,000 Ordinary Shares.

C        RBML  have  agreed  to  procure  the  Trustee  to  subscribe,  over two
         tranches,  for  up  to  2,000,000  Series  A  Preferred  Shares,  at  a
         subscription  price of $1.00 per Share, on the terms and conditions set
         out in this  Agreement.  The first tranche will be for 250,000 Series A
         Preferred  Shares for a total  consideration of $250,000 and the second
         tranche  will be for  1,750,000  Series A Preferred  Shares for a total
         consideration of $1,750,000.

D        The parties  have agreed that their  relationship  shall be governed by
         the terms and conditions set out in this Agreement.

<PAGE>

NOW IT IS AGREED:

1        DEFINITIONS AND INTERPRETATION

         1.1      DEFINITIONS

                  In this Agreement, unless the context otherwise requires:

                  "Anutech"  means  Anutech  Pty Ltd  (A.C.N.  008  548  650) of
                  Anutech Court,  corner Barry Drive and Daley Road,  Australian
                  Capital Territory 2601;

                  "Associate"  has the  meaning  ascribed  to  that  term in the
                  Corporations Law;

                  "Board" or "the Directors" means the Board of Directors of the
                  Company as constituted from time to time;

                  "Business"  means  the  drug  development  operations  of  the
                  Company;

                  "Business  Day"  means  a day on  which  banks  are  open  for
                  domestic business in Melbourne  excluding  Saturdays,  Sundays
                  and public holidays;

                  "Business  Plan"  means the  business  plan of the  Company in
                  place from time to time;

                  "Confidentiality  Deed" means a deed substantially in the form
                  of the confidentiality deed set out in Schedule 1;

                  "Commencement  Date"  means the third  Business  Day after the
                  date on which the condition precedent set out in Clause 2.1 is
                  satisfied or such other date as the parties may agree;

                  "Constitution" means the constitution of the Company;

                  "Corporations  Law" means the Corporations Law of Victoria or,
                  where applicable,  any other  Corporations Law of any State or
                  Territory;

                  "Deed of Accession" means a deed  substantially in the form of
                  the deed of accession set out in Schedule 2;

                  "Dispose"  means,  in relation to any  relevant  property,  to
                  sell,  transfer,  assign,  create an Encumbrance over, declare
                  oneself a trustee  of or part with a benefit  of or  otherwise
                  dispose of the relevant property (or any interest therein) and
                  includes,  without limitation, in relation to a share to enter
                  into a  transaction  in relation to the share (or any interest
                  therein), other than a transaction permitted by this Agreement
                  or the Constitution,  which results in a person other than the
                  registered holder of the share:

<PAGE>

                  (a)  acquiring any equitable interest in the share, including,
                       but  not  limited  to,  an  equitable   interest  arising
                       pursuant to a declaration of trust, an agreement for sale
                       and  purchase of or an option  agreement  or an agreement
                       creating a charge or other  security  interest in respect
                       of the share;


                  (b)  acquiring any right to receive directly or indirectly any
                       dividends payable in respect of the share;

                  (c)  acquiring  any rights of  pre-emption,  first  refusal or
                       like control over the disposal of the share;

                  (d)  acquiring  any rights of control over the exercise of any
                       voting rights or rights to appoint Directors attaching to
                       the share; or

                  (e)  otherwise acquiring legal or equitable rights against the
                       registered  holder of the share  which have the effect of
                       placing the person in the same position as would exist if
                       the person had acquired a legal or equitable  interest in
                       the share itself;

                  "Dividend" includes a bonus distribution in specie or in cash;

                  "Eligible Investee Company" has the meaning given to that term
                  in the IIF Program Guidelines No. 1 of 1998 established by the
                  Industry Research and Development Board acting under Part 2 of
                  the IIF Program,  Policies and  Practices  Direction  No. 1 of
                  1997 (as amended  from time to time,  whether  generally or in
                  relation to any Licensed Fund);

                  "Employee  Share  Plan"  means an  employee  share  or  option
                  incentive  plan  proposed  to be  introduced  by  the  Company
                  pursuant to Clause 10;

                  "Encumbrance" means any mortgage, pledge, lien, hypothecation,
                  charge or other form of  security  interest or interest in the
                  nature of a security interest whatsoever;

                  "Group"  means the Company and its  subsidiaries  (if any) for
                  the time being;

                  "IIF  Management  Licence"  means  an IIF  Program  management
                  licence executed between the Industry Research and Development
                  Board on behalf of the  Commonwealth  of Australia and a Party
                  to this Agreement;

                  "IIF Program"  means the  Innovation  Investment  Fund Program
                  established  by  the   Commonwealth  of  Australia  under  the
                  Industry Research and Development Act 1986 (Clth.);

                  "Licence Agreements" means the licence agreements entered into
                  on or about the date of this  Agreement  between  Anutech  and
                  Praxis USA and between Anutech and the Company;

<PAGE>

                  "Licence  and  Research &  Development  Agreements"  means the
                  Licence and  Research &  Development  Agreement  entered  into
                  between  Anutech  and Praxis  USA on 27  October  1997 and the
                  Addendum to the Licence and Research &  Development  Agreement
                  dated 8 October 1998;

                  "Licensed Fund" means a fund of whatever nature, and whether
                  incorporated or not:

                  (a)  which,  or the  manager  of  which,  is to be or has been
                       granted an IIF Management License; and

                  (b)  the manager or trustee of which is a Shareholder;

                  "Ordinary  Shares"  means the  ordinary  Shares of the Company
                  having the rights ascribed to them by the Constitution;

                  "Party" means a party to this  Agreement and includes a person
                  who executes a Deed of Accession;

                  "Preferred  Shareholder"  means a Party  who  holds a Series A
                  Preferred  Share and includes a Party who holds the beneficial
                  interest in a Series A Preferred Share  registered in the name
                  of another person as nominee for that Party;

                  "Proposing  Transferor"  means a Shareholder  that proposes to
                  Dispose of any Shares held by it;

                  "Related Body Corporate" has the meaning ascribed to that term
                  in the Corporations Law;

                  "Relevant Event" means, in relation to a Shareholder:

                  (a)  that  Shareholder  making any  arrangement or composition
                       with its creditors generally or any or all of them (other
                       than for the  purposes  of a bona fide  scheme of solvent
                       amalgamation  or   reconstruction   to  which  the  other
                       Shareholders have consented in writing);

                  (b)  that Shareholder becoming insolvent within the meaning of
                       that expression in the Corporations Law;

                  (c)  a receiver, manager, receiver and manager,  administrator
                       or trustee or other like custodian being appointed by any
                       person   over   all  or  a   substantial   part  of  that
                       Shareholder's  undertaking  or assets and such  receiver,
                       manager, receiver and manager, administrator,  trustee or
                       other like custodian is not discharged  within 60 days of
                       being appointed;

                  (d)  that  Shareholder  having a petition or summons lodged or
                       an order made or a resolution  passed for its liquidation
                       or winding up (other than a voluntary liquidation for the
                       purposes of a

<PAGE>

                       bona   fide   scheme   of   solvent    amalgamation    or
                       reconstruction  to  which  the  other  Shareholders  have
                       consented in writing)  which is not discharged or revoked
                       within 30 days; or

                  (e)  the power,  whether held  directly or  indirectly  and by
                       whatever means  (whether or not  enforceable at law or in
                       equity):

                       (i)  to exercise or control the right to vote attached to
                            no  less  than  50% of the  issued  shares  in  that
                            Shareholder;

                       (ii) to Dispose of or exercise a right of  disposal  over
                            not  less  than  50% of the  issued  Shares  of that
                            Shareholder;

                       (iii)to  control   the   composition   of  the  board  of
                            directors  of  that  Shareholder   (which  shall  be
                            determined  having  regard  to  Section  47  of  the
                            Corporations Law); or

                       (iv) to  determine  substantially  the  conduct  of  that
                            Shareholder's business activities,

                       shall reside in any persons other than those holding such
                       power  on the  date on which  that  Shareholder  became a
                       Shareholder;

                  "Relevant Shares" means in relation to a transferee of Shares,
                  the Shares  originally  transferred  to the Transferee and any
                  additional  Shares issued or  transferred to the Transferee by
                  virtue of the holding of those Shares or any of them;

                  "Second  Tranche  Date" means the date 10 Business  Days after
                  the Investors  have received a patent review  satisfactory  to
                  them  from  a  patent  attorney  specified  by  the  Investors
                  following the filing of a patent application in respect of new
                  compounds in accordance with the Business Plan;

                  "Senior  Employee"  means  an  employee  whose  rate of  gross
                  contractual salary is $75,000 per annum or more;

                  "Series  A  Preferred   Shares"   means  Series  A  Redeemable
                  Convertible  Preferred  Shares in the  capital of the  Company
                  having the rights ascribed to them by the Constitution;

                  "Share" means a share in the capital of the Company including,
                  without  limitation,  Ordinary  Shares and Series A  Preferred
                  Shares;

                  "Shareholder"  means a Party who holds  Shares and  includes a
                  Party who holds the beneficial  interest in Shares  registered
                  in the name of another person as nominee for that Party;

                  "Specified Proportion" means, in relation to a Shareholder,  a
                  fraction  the  numerator of which is the number of Shares held
                  by that  Shareholder for the time being and the denominator of
                  which is

<PAGE>
                  the total number of Shares  (including  the Shares held by the
                  said  Shareholder)  in issue for the time being (assuming that
                  in so  calculating  the number of Shares held by a Shareholder
                  and the  total  number  of  Shares  in  issue,  all  Series  A
                  Preferred Shares have been converted in to Ordinary Shares);

                  "Subsidiary"  has the  meaning  ascribed  to that  term by the
                  Corporations Law;

                  "Transfer  Notice"  means a  Transfer  Notice  delivered  by a
                  Shareholder pursuant to Clause 8.3(b);

                  "Transfer Shares" means the Shares that a Proposing Transferor
                  proposes to Dispose of;

                  "Trust" means the Australian Bioscience Trust constituted by a
                  deed of trust dated 20 August 1998 between Perpetual and RBML;

                  "Trust Deed" means the deed of trust  constituting  the Trust;
                  and

                  "Trustee"  means  Perpetual  and any  substitute or additional
                  trustee appointed to the Trust.

        1.2       INTERPRETATION

                  In this  Agreement,  including  the  Recitals,  except  to the
                  extent that the subject or the context otherwise requires:

                  (a)  reference to any  legislation  or to any provision of any
                  legislation shall include any modification or re-enactment of,
                  or  any  legislative   provision   substituted  for,  and  all
                  legislation  and  statutory  instruments  issued  under,  such
                  legislation   or  such   provision   and  shall   include  the
                  corresponding  legislation in such other State or Territory of
                  the  Commonwealth of Australia as may be relevant from time to
                  time;

                  (b) words (including words defined in this Agreement) denoting
                  the singular number shall include the plural and vice versa;

                  (c) words importing natural persons will include corporations,
                  firms, unincorporated associations,  partnerships,  trusts and
                  any other entities recognised by law and vice versa;

                  (d) words denoting any gender shall include all genders;

                  (e) the words "WRITTEN" and "IN WRITING"  include any means of
                  visible  reproduction  of words in a tangible and  permanently
                  visible form;

                  (f)  reference  to Clauses and  Schedules  are  references  to
                  clauses and schedules of this Agreement;

<PAGE>
                  (g) where a word or phrase is  defined,  other parts of speech
                  and  grammatical  forms  of that  word or  phrase  shall  have
                  corresponding meanings;

                  (h) reference to any document or agreement  shall be deemed to
                  include  references  to such document or agreement as novated,
                  supplemented, varied or replaced from time to time;

                  (i) no rule of construction  applies to the  disadvantage of a
                  party because that party was  responsible  for the preparation
                  of this Agreement or any part of it; and

                  (j) a reference to the ownership of Shares by a Shareholder or
                  the Shares held by a Shareholder shall include, in relation to
                  a Party who holds the beneficial interest in Shares registered
                  in the name of another  person as nominee  for that  Party,  a
                  reference to the  beneficial  ownership of such Shares by that
                  Party or the Shares the  beneficial  interest in which is held
                  by that Shareholder.

        1.3       HEADINGS

                  The headings to Clauses or  Schedules  are for the purposes of
                  more  convenient  reference  only and do not form part of this
                  Agreement or effect its interpretation.

        1.4       ACKNOWLEDGEMENT

                  RBML  acknowledges the provisions of this Agreement and agrees
                  and undertakes  that to the extent of its powers as manager of
                  the  Trust  that it  shall  exercise  all such  powers  as are
                  available  to it under  the  Trust  Deed,  do all  such  acts,
                  matters  and things and sign,  execute  and  deliver  all such
                  instructions  and  documents  to require the Trustee to comply
                  with its obligations under this Agreement.


2       CONDITION PRECEDENT

        2.1 This  Agreement and the  performance of all  obligations  under this
        Agreement  (other than  obligations  under this Clause 2) are subject to
        and  conditional  upon  the  Constitution  being  amended  as set out in
        Schedule 3.

        2.2 The Company must ensure that the  condition  precedent in Clause 2.1
        is satisfied on or before 31 October 1999.

        2.3 If the  condition  precedent  in Clause 2.1 is not  satisfied  on or
        before 31 October  1999 (or such other date as the  parties  may agree),
        this Agreement  (other than this Clause 2) is  automatically  terminated
        without any of the parties  being liable to any other party  pursuant to
        this Agreement except under this Clause 2.

<PAGE>

        2.4 If the Second  Tranche  Date has not  occurred  on or before [ ], or
        such other  date as the  Investors  agree,  the  Investors'  obligations
        pursuant to Clause 3.2 are automatically terminated.


3       CAPITALISATION OF THE COMPANY AND OTHER MATTERS

        3.1  On the  Commencement  Date  RBML  will  procure  that  the  Trustee
        subscribe for a total of 250,000 fully paid Series A Preferred Shares at
        a price of $1.00  per Share and  shall  accordingly  complete,  sign and
        deliver  to the  Company  an  application  form in respect of the Shares
        being  subscribed for by it accompanied by a cheque for the subscription
        monies due.

        3.2 On the Second  Tranche  Date,  RMBL will  procure  that the  Trustee
        and/or such other  persons as RBML  determines  subscribe for a total of
        1,750,000  fully paid Series A Preferred  Shares at a price of $1.00 per
        share and shall accordingly  complete sign and deliver to the Company an
        application  form in respect of the Shares  being  subscribed  for by it
        accompanied  by a cheque for the  subscription  monies  due.  Any person
        (other than the Trustee) who  subscribes  for Series A Preferred  Shares
        pursuant to this clause shall  execute a Deed agreeing to become a Party
        to this Agreement in a form acceptable to RBML.

        3.3 The Company  shall,  upon each  receipt  from the  applicant  of its
        respective   applications,   subscription  monies  or  consideration  in
        accordance  with Clauses 3.1 and 3.2, issue and allot Series A Preferred
        Shares to the Trustee in accordance with each respective application and
        issue the Trustee with share certificates for its respective Shares.

        3.4 Unless  otherwise  agreed in writing between the  Shareholders,  the
        subscription  monies referred to in Clauses 3.1 and 3.2 shall be applied
        by the Company  solely for the  purposes of the  Business as detailed in
        the Business Plan.


4       FURTHER FINANCING

        4.1  Except  as  otherwise  provided  in  this  Agreement,  none  of the
        Shareholders  undertakes  to  provide  any loan or Share  capital to the
        Company or to give any  guarantee  or indemnity in respect of any of the
        Company's liabilities or obligations.

        4.2 If,  at any time  prior  to a public  offering  of any  Shares,  the
        Company wishes to raise further funds,  the Company must first offer the
        right  to  provide  to  the  Company  all of the  further  funds  to the
        Preferred  Shareholders  in proportion to their  respective  holdings of
        Series A Preferred Shares. If any Preferred Shareholder does not wish to
        provide all or part of its  proportion of the further  funds,  the other

<PAGE>

        Preferred  Shareholders  shall have the right to provide  those  further
        funds in proportion to their  respective  holdings of Series A Preferred
        Shares.

5       PUBLIC OFFERING

        5.1 Each party (other than the Trustee) shall use its best endeavours to
        ensure  that an initial  public  offering of the Shares on the terms set
        out in Clause  5.2,  or any other  means by which the  Shareholders  can
        realise the value of their  investment  in the Shares,  occurs within 36
        months from the Commencement Date.

        5.2 It is intended that the initial  public  offering raise at least $10
        million by the offer of Shares at an issue  price of at least  $3.00 per
        share.


6       DIVIDEND POLICY FOR ORDINARY SHARES

        6.1 The  Parties  agree that there is no existing  intention  to declare
        Dividends on any Ordinary  Shares,  and that no declaration of Dividends
        on any  Ordinary  Shares  shall occur until such time as the Company has
        generated  sufficient  profits  from the  Business  as would  enable all
        Dividends  that have accrued on Series A Preferred  Shares,  pursuant to
        the Constitution,  to be met in full were those Dividends payable on the
        day the Dividend on the Ordinary Shares is to be declared.

        6.2 Subject to Clause 6.1, the  Directors  shall  determine  whether the
        Company shall pay a Dividend on the Ordinary Shares in any year.


7       DISPOSAL AND ENCUMBRANCE OF SHARES

        7.1 Subject to Clause 7.2, a Shareholder  shall not Dispose of any legal
        or equitable interest in any of its Shares except:

                  (a)  by a transfer of the entire legal and beneficial interest
                       therein; and

                  (b)  to a transferee  permitted by the  Constitution  and this
                       Agreement.

        7.2 A  Shareholder  may create an  Encumbrance  in respect of any of its
        Shares if:

                  (a)  BONA FIDE SECURITY

                       (i)  such  Encumbrance  is granted  bona fide as security
                            for a financing arrangement; and

<PAGE>

                       (ii) in relation to the  exercise or  enforcement  of any
                            power  of sale or  other  right,  power,  authority,
                            remedy or discretion contained in or conferred under
                            or  pursuant   to  the   instrument   creating   the
                            Encumbrance or otherwise howsoever,  it is a term or
                            condition that the person entitled to the benefit of
                            the  Encumbrance  ("the  Chargee")  and  any  person
                            (including  any  receiver or receiver  and  manager)
                            claiming  through the Chargee  ("an  Administrator")
                            shall be required to:

                            (1)  comply in all respects  with the  provisions of
                                 this Agreement and the  Constitution  as if the
                                 Chargee  and the  Administrator  were  each the
                                 applicable Shareholder; and

                            (2)  covenant  with the  Shareholders  by a  written
                                 instrument in such form as the Shareholders may
                                 require   that   if   the   Chargee   and   the
                                 Administrator   (or   either   of  them)   take
                                 possession  of the  rights or  benefits  of the
                                 applicable  Shareholder  under this  Agreement,
                                 which  are  subject  to  the  Encumbrance,  the
                                 Chargee  and  the  Administrator  will  each be
                                 bound by the  provisions of this  Agreement and
                                 the Chargee and the Administrator (or either of
                                 them)  will  not  exercise  any  power  of sale
                                 pursuant  to the  Encumbrance,  except on terms
                                 the same mutatis mutandis as those set forth in
                                 this Agreement and the Constitution; or

                  (b)  the prior written  consent of all other  Shareholders  is
                       obtained.


8        TRANSFER OF SHARES

         Notwithstanding anything to the contrary contained in this Agreement or
         in the Constitution:

         8.1      TRANSFER OF SHARES

                  (a)  The Company  shall refuse to register the transfer of any
                       Share unless the transferee has or the  transferees  have
                       entered into a Deed of Accession and:

                       (i)  such  transfer is permitted  by, or is made pursuant
                            to and in accordance with,  Clauses 8.3, 8.4, 8.5 or
                            8.6 or the  provisions  of any  agreement in writing
                            between all the Shareholders; or

                       (ii) the  proposed  transferee  is approved in writing by
                            all the  Shareholders  (other than the Transferor of
                            the Share) before any instrument is executed to give
                            effect  to  such

<PAGE>
                            transfer and,  subject to such approval being given,
                            Clause 8.3 shall not apply to such transfer.

                  (b)  Subject  to  Clause  8.1(c),  the  Company  shall  not be
                       entitled to decline to register the transfer of any Share
                       which  otherwise  qualifies  under  Clauses  8.1(a)(i) or
                       8.1(a)(ii).

                  (c)  For the purpose of ensuring that a particular transfer of
                       Shares is  permitted  under this  Agreement  or under the
                       provisions  of any  agreement in writing  between all the
                       Shareholders,  the Company may require the  transferor or
                       the person named as transferee in any transfer lodged for
                       registration to furnish the Company with such information
                       and  evidence  as the  Company  may  think  necessary  or
                       relevant.  Failing  such  information  or evidence  being
                       furnished to the satisfaction of the

                  Company  within a period of 28 days  after such  request,  the
                  Company  shall be entitled to refuse to register  the transfer
                  in question.

         8.2      PERMITTED TRANSFERS

                  (a)  A Shareholder  may at any time transfer any of the Shares
                       held by it to the  ultimate  beneficial  owner  of  those
                       Shares at the time of transfer.

                  (b)  A transfer of any Shares  pursuant  to this Clause  shall
                       only  be  treated  as a  permitted  transfer  if  it is a
                       transfer of the entire legal  interest in such Share free
                       from all Encumbrances.

                  (c)  If a transfer  pursuant to Clause  8.2(a) is to more than
                       one ultimate  beneficial owner,  those Shares transferred
                       and the rights and obligations under this Agreement shall
                       be held by and bind them jointly.

         8.3      PRE-EMPTIVE RIGHTS

                  (a)  Except as provided in Clauses  8.1,  8.2,  8.5 and 8.6 no
                       Share may be  Disposed of unless the  procedure  provided
                       for in this Clause is followed.

                  (b)  A Proposing Transferor shall be obliged to give notice in
                       writing  to the  Company  that the  Proposing  Transferor
                       desires to Dispose of such Shares.  The  Transfer  Notice
                       shall specify:

                       (i)  the number and class of the Transfer Shares;

                       (ii) the price at which the Proposing  Transferor  wishes
                            to Dispose of the  Transfer  Shares  (the  "Transfer
                            Price"); and

                       (iii)the  identity  of a person who has  indicated a bona
                            fide  willingness to purchase the Transfer Shares at
                            such price (the "Transferee").

<PAGE>

                  (c)  The Transfer  Notice shall  constitute the Company as the
                       agent of the Proposing  Transferor  empowered to sell the
                       Transfer  Shares  (together  with  all  rights  attaching
                       thereto at the date of the Transfer Notice or at any time
                       thereafter)  at the  Transfer  Price on the terms of this
                       Clause 8.3.

                  (d)  The Transfer  Notice  shall not be revocable  except with
                       the prior written consent of all the Shareholders.

                  (e)  Within 7 days after the  receipt of any  Transfer  Notice
                       the Company shall serve a copy of that Transfer Notice on
                       all the Preferred  Shareholders  other than the Proposing
                       Transferor  (if  applicable).  In the  case  of a  deemed
                       Transfer Notice, the Company shall similarly serve notice
                       on  all  the  Preferred   Shareholders   (including   the
                       Proposing  Transferor)  notifying  them that the same has
                       been deemed to have been given.

                  (f)  Subject as provided  otherwise in this  Agreement,  or in
                       any  agreement in writing  between all the  Shareholders,
                       the  Transfer  Shares shall first be offered for purchase
                       at the Transfer Price by the Company to all the Preferred
                       Shareholders (other than the Proposing Transferor) in the
                       Specified Proportions of those Preferred Shareholders.

                  (g)  Any offer made pursuant to Clause 8.3(f) shall be made by
                       notice in writing and shall specify:

                       (i)  the number and class of the Transfer Shares;

                       (ii) the   proportionate   entitlement  of  the  relevant
                            Preferred Shareholder;

                       (iii) the Transfer Price; and

                       (iv) a period of 14 days  within  which the offer must be
                            accepted or shall lapse.

                  (h)  If the Company does not receive acceptances in respect of
                       all the Transfer  Shares within the periods of the offers
                       referred to in Clause 8.3(g), the Company shall forthwith
                       give  notice in  writing  of that  fact to the  Proposing
                       Transferor and the remaining  Transfer  Shares in respect
                       of  which   acceptances  have  not  been  received  shall
                       thereafter  be  offered,  pro-rata,  to  those  Preferred
                       Shareholders  who  have  accepted  an  offer  within  the
                       periods of the offers  referred to in Clause 8.3(g).  Any
                       offer made  pursuant to this Clause  8.3(h) shall be made
                       in accordance with Clause 8.3(g),  except that the period
                       within which all offers must be accepted  before  lapsing
                       shall be 14 days.

<PAGE>

                  (i)  Subject to Clause 8.4,  if the  Company  does not receive
                       acceptances in respect of all the Transfer  Shares within
                       the periods of the offers  referred to in Clauses  8.3(g)
                       or 8.3(h),  the Company  shall  forthwith  give notice in
                       writing of that fact to the Proposing Transferor, and the
                       Proposing  Transferor  may  within a  period  of 3 months
                       after the date of such notice sell the Transfer Shares to
                       the Transferee  named in the Transfer Notice at any price
                       which  is  not  less  than  the  Transfer   Price  (after
                       deducting, where appropriate, any Dividend declared, paid
                       or made after the date of the Transfer  Notice in respect
                       of the  Transfer  Shares  and  which has been or is to be
                       retained by the Proposing Transferor).

                  (j)  If  any   person   or   persons   (including   any  other
                       Shareholder) (the "Purchasers")  agree within the periods
                       referred  to in Clauses  8.3(g),  (h) or (i) (as the case
                       may  be) to  purchase  all of the  Transfer  Shares,  the
                       Company  shall  forthwith  give  notice in writing to the
                       Proposing  Transferor  and  to  the  Purchasers  and  the
                       Proposing  Transferor  shall thereupon  become bound upon
                       payment of the Transfer Price to the Proposing Transferor
                       (whose receipt shall be a good discharge to the Purchaser
                       and the Company  therefor  none of whom shall be bound to
                       see  the   application   thereof)  to  transfer  to  each
                       Purchaser those Transfer  Shares accepted by them.  Every
                       such  notice  shall  state the name and  address  of each
                       Purchaser,  the number of  Transfer  Shares  agreed to be
                       purchased  by it and the place and time  appointed by the
                       Company for the  completion  of the  purchase  (being not
                       less than 7 days nor more than 28 days  after the date of
                       the said  notice  and not  being at a place  outside  New
                       South Wales).  Subject to the giving of such notice,  the
                       purchase  shall  be  completed  at  the  time  and  place
                       appointed by the Company.

                  (k)  If  a  Proposing  Transferor,   having  become  bound  to
                       transfer any Transfer Shares pursuant to this Clause 8.3,
                       makes  default in  transferring  the same the Company may
                       authorise  some  person  (who  shall be  deemed to be the
                       attorney of the Proposing  Transferor for the purpose) to
                       execute  the  necessary  instrument  of  transfer of such
                       Transfer  Shares and may deliver it on its behalf and the
                       Company  may  receive  the   purchase   money  and  shall
                       thereupon (subject to such instrument being duly stamped)
                       cause the  Transferee  to be  registered as the holder of
                       such Transfer  Shares and shall hold such purchase  money
                       on behalf of the Proposing Transferor.  The Company shall
                       not be  bound  to earn or pay  interest  on any  money so
                       held.  The receipt of the Company for such purchase money
                       shall be a good  discharge to the  Transferee  (who shall
                       not be bound to see to the application thereof) and after
                       the  name  of the  Transferee  has  been  entered  in the
                       register of  Shareholders  in  purported  exercise of

<PAGE>
                       the power conferred  pursuant to this Clause 8.3(k),  the
                       validity of the  proceedings  shall not be  questioned by
                       any person.

                  (l)  Without  limiting Clause 8.1(c),  the Company may require
                       to be satisfied that any Shares being  transferred by the
                       Proposing  Transferor pursuant to Clause 8.3(i) are being
                       transferred  in  pursuance  of a bona  fide  sale for the
                       consideration  stated  in  the  transfer  and  if  not so
                       satisfied  may  refuse  to  register  the  instrument  of
                       transfer.

         8.4      TRANSFER ON A RELEVANT EVENT

                  (a)  Upon the happening of a Relevant  Event,  the Shareholder
                       in question shall be deemed to have  immediately  given a
                       Transfer  Notice in  respect  of all the  Shares as shall
                       then be registered in the name of that Shareholder.

                  (b)  In the case of a Transfer  Notice being given pursuant to
                       Clause  8.4(a),  the price per Transfer Share which is so
                       specified in the Transfer Notice shall be:

                       (i)  such price as shall be agreed in writing between all
                            of the Shareholders; or

                       (ii) in the  absence  of such  agreement  within  14 days
                            after  the  date on which  the  Transfer  Notice  is
                            deemed  to  have  been  given,  the  price  will  be
                            determined by an  independent  Chartered  Accountant
                            (the  "Expert")  nominated by agreement  between all
                            the Shareholders or, failing such nomination  within
                            14 days after the request of any  Shareholder to the
                            others  therefor,  nominated  at the  request of any
                            Shareholder  by the  President or other head for the
                            time being of the Institute of Chartered Accountants
                            of Australia.  The Expert shall act as an expert and
                            not as an arbitrator  and his written  determination
                            shall in the absence of manifest  error be final and
                            binding on all the  Shareholders.  For the foregoing
                            purpose,  the Expert  shall have access to all books
                            of account and records  and all  vouchers,  cheques,
                            papers and  documents  that in any way relate to the
                            Business or the Company.

                  (c)  The Expert  will  certify in writing  the sum that in his
                       opinion is the fair market value of the Transfer  Shares.
                       The price  per  Share  shall be the sum equal to the fair
                       market  value of the  Transfer  Shares  (of  that  class)
                       certified  by  that  Expert  divided  by  the  number  of
                       Transfer Shares (of that class). The Company will use its
                       best endeavours to procure that the Expert determines the
                       price per Share  within 21 days of being  requested to do
                       so.


<PAGE>
                       The costs and expenses of the Expert in  determining  the
                       price  per  Share  shall  be  borne as to one half by the
                       Proposing  Transferor  and as to the  other  half  by the
                       Purchasers   (as  defined  in  Clause  8.3(j))  pro  rata
                       according to the number of Transfer  Shares  purchased by
                       them.

         8.5      CO-SALE

                  (a)  If a Proposing  Transferor is permitted under this Clause
                       8 to  sell  all or any of its  Shares  to a  third  party
                       purchaser  and the  provisions  of  Clause  8.3 have been
                       complied  with or waived by the  Preferred  Shareholders,
                       each of the Preferred Shareholders will have the right to
                       require by notice in  accordance  with Clause  8.5(b) the
                       Proposing  Transferor  to  procure  that the third  party
                       acquire  Shares from each of the  Preferred  Shareholders
                       who  delivers  such a notice,  the number of Shares to be
                       calculated by multiplying  the number of Transfer  Shares
                       by   the   Specified   Proportion   of   that   Preferred
                       Shareholder,  at the same price per Share and on the same
                       terms and  conditions as the third party  purchaser is to
                       acquire the Proposing  Transferor's Shares and, if any of
                       the other Preferred Shareholders gives notice pursuant to
                       this Clause 8.5, the  Proposing  Transferor  will only be
                       permitted to sell its Shares to the third party purchaser
                       if the third party  purchaser  also acquires the relevant
                       number of the other Preferred Shareholders' Shares at the
                       same   price  per  Share  and  on  the  same   terms  and
                       conditions.

                  (b)  A notice for the  purposes of Clause  8.5(a)  shall be in
                       writing  addressed to the Proposing  Transferor and given
                       to the Proposing  Transferor within 14 days of receipt by
                       the  other  Preferred  Shareholder  of a notice  from the
                       Proposing Transferor specifying the identity of the third
                       party purchaser, price per Share and terms and conditions
                       on which  the  Proposing  Transferor's  Shares  are to be
                       sold.

                  (c)  A  Preferred   Shareholder   other  than  the   Proposing
                       Transferor  may  sell  its  Shares  to  the  third  party
                       purchaser in accordance  with Clause  8.5(a)  without the
                       need to comply with the procedure set out in Clause 8.3.

         8.6      TRANSFER OF ENTIRE INTEREST

                  An obligation to transfer a Share under the provisions of this
                  Clause 8 shall be deemed to be an  obligation  to transfer the
                  entire legal and  beneficial  interest in such Share free from
                  any Encumbrance.

<PAGE>

         8.7      WAIVER OF PROVISIONS

                  The  provisions  of this Clause 8 may be waived in whole or in
                  part in any particular  case with the prior written consent of
                  all the Shareholders.

         8.8      SHAREHOLDER OBLIGATION

                  Each  Shareholder  shall do  everything  within  its power and
                  shall not fail to do anything  within its power to ensure that
                  Shares in itself are not  Disposed  of in order to overcome or
                  avoid the transfer provisions of Clause 8.


9        ALLOTMENT OF SHARES

         9.1      If, at any time  prior to a public  offering  of any Shares of
                  the  Company,  the  Company  issues any  additional  Shares or
                  securities convertible into Shares, the Company shall offer to
                  each Preferred Shareholder for subscription, at the same price
                  and on the  same  terms  and  conditions,  sufficient  of such
                  Shares or securities as will enable that Preferred Shareholder
                  to maintain its  proportionate  ownership  of Ordinary  Shares
                  after such issue,  assuming that in so calculating  the amount
                  of Shares or securities  to be offered and each  Shareholder's
                  proportionate  ownership of Ordinary Shares, all issued Series
                  A Preferred Shares have been converted into Ordinary Shares.

         9.2      Clause 9.1 shall not apply to Shares or  securities  issued to
                  employees, consultants or directors for incentive purposes.

10       EMPLOYEE SHARE OR OPTION INCENTIVE PLAN

         The Parties  acknowledge that it is intended that, after the completion
         of certain milestones, the Company will create and maintain an employee
         share or option  incentive  plan on the basis that if the  shares  were
         issued or options  were  fully  exercised,  the shares so issued  would
         constitute up to 15% of the Ordinary  Shares on issue  determined as if
         all shares,  and securities  convertible in to Ordinary Shares had been
         converted,  and on such other terms and conditions as are determined by
         the Board.

11       WARRANTIES, UNDERTAKINGS AND OBLIGATIONS

         11.1     The Company represents and warrants to each of the manager and
                  trustee of each Licensed Fund that it is an Eligible  Investee
                  Company and there has been no material  adverse  change to the
                  financial  position  of the  Company as at  September  1999 as
                  described in the Business Plan; and

<PAGE>

         11.2     The Company shall:

                  (a)  proactively  inform the manager of each Licensed Fund and
                       respond to any requests from a manager of a Licensed Fund
                       in a timely and  expeditious  manner,  of any information
                       concerning  the  status  of the  Company  as an  Eligible
                       Investee  Company  or  a  change  in  the  status  of  an
                       Associate or Related Body  Corporate of the Company,  and
                       any  information  that a manager of a  Licensed  Fund may
                       require to comply with its obligations under the relevant
                       IIF Management Licence;

                  (b)  provide to the manager of each  Licensed Fund on the date
                       of  this  Agreement  and  thereafter  within  14  days of
                       receiving a request from a manager of a Licensed  Fund so
                       to provide  (on at least an annual  basis) the  following
                       information:

                       (i)  the names of all officers and senior  executives  of
                            the Company and its Related Bodies Corporate;

                       (ii) the  names  of  all  the  Company's  Related  Bodies
                            Corporate;

                       (iii)confirmation  that  no  moneys  invested  by,  or on
                            behalf of, a Licensed Fund will be used to discharge
                            a debt to, or acquire an asset from,  the manager or
                            trustee of a Licensed Fund or any of their  officers
                            or Related Bodies Corporate;

                       (iv) confirmation  that the Company will not be acquiring
                            any goods or services from the manager or trustee of
                            the  Licensed  Fund  or any  of  their  officers  or
                            Related Bodies Corporate;

                       (v)  confirmation that the Company does not owe any money
                            on any account whatever to the manager or trustee of
                            a Licensed Fund or any of their  officers or Related
                            Bodies Corporate; and

                       (vi) confirmation  that in respect of any other holder of
                            a IIF  Management  Licence or another  Licensed Fund
                            ("Other Relevant Party"), the Company:

                            (1)  cannot Control,  or influence  materially,  the
                                 Other Relevant  Party's  activities or internal
                                 affairs;

                            (2)  is not a member or beneficiary of or partner in
                                 the Other Relevant Party;

                            (3)  is not in a position to cast, or to Control the
                                 casting  of, a vote at a meeting  of the equity
                                 holders  in  the  Other  Relevant  Party  or to
                                 Control  or  influence

<PAGE>

                                 materially the Other Relevant  Party's internal
                                 affairs;

                            (4)  has no  power to  dispose  of,  or to  exercise
                                 Control  over the disposal of, a security in or
                                 issued by the Other Relevant Party;

                            (5)  is not owed a debt by and is not a creditor  of
                                 the Other Relevant Party; or

                            (6)  does not act as agent  for the  Other  Relevant
                                 Party in any transaction or dealing,

                  (c)  represent  and warrant that the  information  provided by
                       the  Company  pursuant  to  clause  11.2(b)  is true  and
                       correct; and

                  (d)  ensure  that  it  does  all  matters  and  things  as are
                       confirmed  in the  information  provided  by the  Company
                       pursuant to clause 11.2(b).

                  (e)  A  reference  in  this  Clause  11.2  to  "Control"  of a
                       corporation is a reference to the possession  directly or
                       indirectly of the power whether or not having  statutory,
                       legal or  equitable  force,  and  whether or not based on
                       statutory,   legal  or  equitable  rights,   directly  or
                       indirectly to:

                       (i)  control more than 50% of the membership of the board
                            of directors of that corporation; or

                       (ii) control more than 50% of its voting shares; or

                       (iii)direct or cause the direction of the  management and
                            policies of the manager,

                  whether   by  means  of  trusts,   agreements,   arrangements,
                  understandings,  practices,  the  ownership of any interest in
                  shares or stock of that company or otherwise.

                  (f)  A  reference  in  this  Clause  11.2  to  "Control"  of a
                       corporation  or other person who is or proposes to act as
                       a trustee is a reference  to the  possession  directly or
                       indirectly of the power to:

                       (i)  control the trustee;

                       (ii) control any  decisions  of the trustee as trustee of
                            the relevant trust;

                       (iii) appoint, remove or replace the trustee;

                       (iv) appoint,   remove  or  replace  a  majority  of  the
                            directors of the trustee; or

<PAGE>

                       (v)  direct  the  allocation  of any  benefits  under the
                            relevant trust.


                  (g)  A reference in this Clause 11.2 to "Control" of an event,
                       outcome  or result  or the  exercise  of a right,  power,
                       authority,  discretion  or remedy  means the  possession,
                       directly  or  indirectly,  of the power to bring about or
                       direct  that  event  outcome  or  result  or  direct  the
                       exercise of that right, power,  authority,  discretion or
                       remedy.


12       MANAGEMENT OF THE COMPANY

         12.1     The Board shall be responsible  for the overall  direction and
                  control of the  management of the Company and the  formulation
                  of the polices to be applied in the conduct of the Business.

         12.2     The Board will consist of 5 directors, namely:

                  (a)  an independent  Chairman  appointed by simple majority of
                       all Shareholders;

                  (b)  a managing  director  appointed by simple majority of all
                       Shareholders;

                  (c)  two  directors   appointed  by  simple  majority  of  all
                       Preferred Shareholders, at least one of whom shall at all
                       times be an appointee of RBML; and

                  (d)  one director appointed by Praxis USA.

         12.3     The  persons  who have  appointed  a director  referred  to in
                  Clause  12.2  shall have the right from time to time to remove
                  any such director and appoint another director in his place.

         12.4     The Company will pay to its non-executive directors:

                  (a)  such fees as are determined by majority of the Board; and

                  (b)  reasonable   travel  and  related  expenses  incurred  in
                       attending  Board  meetings or conducting  business on the
                       Company's behalf and as authorised by the Board.

         12.5     Unless  otherwise  agreed in writing between the  Shareholders
                  and  save  as  otherwise  provided  or  contemplated  in  this
                  Agreement  the  Shareholders  shall  exercise  their powers in
                  relation to the Company so as to ensure that:

                  (a)  the Company  carries on and  conducts  its  business  and
                       affairs in a proper and efficient  manner and for its own
                       benefit;

<PAGE>
                  (b)  the Company transacts all of its business on arm's length
                       terms;

                  (c)  the Company shall  maintain with a  well-established  and
                       reputable insurer adequate insurance coverage against all
                       risks usually  insured  against by companies  carrying on
                       the same or a similar business and (without  prejudice to
                       the generality of the foregoing) for the full replacement
                       or reinstatement  value of all its assets of an insurable
                       nature;

                  (d)  the  Company  allots  and  issues  its  Shares  and other
                       securities at the best price reasonably obtainable in the
                       circumstances;

                  (e)  the Company  shall not  acquire,  dispose,  hire,  lease,
                       licence or receive licences of any assets,  goods, rights
                       or services  otherwise than at the best price  reasonably
                       obtainable in the circumstances;

                  (f)  the Company  shall keep books of account and therein make
                       true  and  complete  entries  of  all  its  dealings  and
                       transactions of and in relation to its business;

                  (g)  the Company fulfils its obligations under this Agreement;

                  (h)  the Company shall prepare its accounts in accordance with
                       the  Corporations  Law and shall  adopt  such  accounting
                       policies as may from time to time be  generally  accepted
                       in Australia;

                  (i)  the Company  shall  prepare  such  accounts in respect of
                       each  financial  year  as are  required  by  statute  and
                       procure  that  such  accounts  are  audited  as  soon  as
                       practicable  and in any event not later than three months
                       after the end of the relevant financial year; and

                  (j)  if the Company requires any approval,  consent or licence
                       for the  carrying on of its Business in the places and in
                       the manner in which it is for the time  being  carried on
                       or  proposed  to be carried on the  Company  will use its
                       best  endeavours  to obtain and maintain the same in full
                       force and effect.

                  The  word  "Company"  where  used in this  paragraph  shall be
                  deemed to include each of the other companies in the Group (if
                  any)  from  time to time to the  intent  and  effect  that the
                  provisions of this Clause 12.5 shall apply in relation to each
                  such company as they apply in relation to the Company.

         12.6     The Company shall provide to each Preferred Shareholder:

                  (a)  annual financial  statements,  certified by an accounting
                       firm of nationally recognised standing within 4 months of
                       the end of each financial year;

<PAGE>

                  (b)  regular    financial    statements    (including   income
                       statements, balance sheets and cash-flow statements) in a
                       form acceptable to the Shareholders;

                  (c)  an annual  operating and financial  plan agreed to by the
                       Board prior to the  beginning of each fiscal year and any
                       revisions  thereof  promptly  upon their  adoption by the
                       Board;

                  (d)  quarterly  technical  summary  updates  measured  against
                       milestones   in  such  form  as  the   Shareholders   may
                       reasonably  require  within  14  days  of the end of each
                       calendar quarter; and

                  (e)  such other  information  as to its financial and business
                       affairs  as  any  Preferred  Shareholder  may  reasonably
                       require.

         12.7     The  Preferred  Shareholders  have the  right at all  times to
                  appoint and instruct an  independent  chartered  accountant to
                  the  Company  for the  purposes  of  reviewing  the  financial
                  statements  and  other  records  and books of  account  of the
                  Company,   and  the  Company  shall  permit  the   independent
                  accountant  reasonable  access  to its  records  and  books of
                  account.  The  costs of the  independent  accountant  shall be
                  borne by the appointing Preferred Shareholder.


13       MEETINGS OF DIRECTORS

         13.1     The Company shall convene meetings of the Directors at least 9
                  times per year or as otherwise agreed from time to time by the
                  Board.

         13.2     After a meeting  of the  Directors  to be held in June of each
                  year the Company  shall  present to each of the  Directors for
                  consideration:

                  (a)  comprehensive   financial   operating  budgets,   capital
                       budgets and cashflow  budgets in a form acceptable to the
                       Directors; and

                  (b)  business   financial   plans  for  the  Company  and  its
                       Subsidiaries (if any) in respect of the period of 3 years
                       to commence on the 1st day of July in that year.

                  13.3  The  quorum  for  a  meeting  of  directors  will  be  3
                  directors,  at  least  one of whom  shall  at all  times be an
                  appointee of a Preferred Shareholder.


14       MATTERS REQUIRING DIRECTORS APPROVAL

         Unless this  Agreement  otherwise  provides,  the Company will not, and
         none of the  other  companies  in the Group (if any) will do any of the
         following,  without the prior approval of a resolution of at least 4 of
         the Directors (one of whom was appointed by RBML):

<PAGE>
         14.1     enter into,  vary or  terminate  any  contract or  arrangement
                  (whether  legally binding or not) with any of its Directors or
                  any  Shareholder  or with  any  Related  Body  Corporate  of a
                  Shareholder;

         14.2     enter into any material  contract or  arrangement  outside the
                  ordinary course of its Business or whereby any person would or
                  might  receive  remuneration  calculated  by  reference to its
                  income or profits;

         14.3     vary   the   terms   of   service   (including   compensation,
                  remuneration and emoluments) of a Director;

         14.4     enter into any  transaction or series of related  transactions
                  (whether at one time or over a period of time)  involving  the
                  incurring  of any  capital  expenditure  or  liability  or the
                  disposal of any capital  asset or assets and which  involves a
                  total outlay or receipt,  in any period of twelve  consecutive
                  months,  of more  than  $100,000  (or such  larger  sum as the
                  Shareholders  may from time to time agree in writing) or a sum
                  equal  to  10% of the  net  assets  of  the  Company  and  its
                  Subsidiaries   (if  any)  as  shown  in  the  latest   audited
                  consolidated  accounts of the Company and its Subsidiaries (if
                  any) or,  if it has no  Subsidiaries,  in its  latest  audited
                  accounts,  whichever amount shall be the higher, but excepting
                  transactions  authorised expressly or impliedly in any current
                  capital  expenditure  budget;  for these purposes  expenditure
                  shall be deemed to be "Capital Expenditure" and an asset shall
                  be deemed to be a "Capital Asset" if, in either case, it would
                  be treated as such in  accounts  prepared in  accordance  with
                  accounting principles generally accepted in Australia;

         14.5     borrow any money or obtain any  advance,  credit or  financial
                  accommodation  in any form (other than normal trade credit not
                  exceeding  $50,000 or other than on normal  banking  terms for
                  unsecured overdraft  facilities not exceeding $50,000) or vary
                  the terms and conditions of any borrowings or bank mandates;

         14.6     create  or  allow to  subsist  any  Encumbrance  over all or a
                  substantial part of all of its assets;

         14.7     lend any money to any  person  (other  than by way of  deposit
                  with a bank or other  institution the normal business of which
                  includes  the  acceptance  of deposits) or grant any credit to
                  any person  (except to its  customers in the normal  course of
                  business)  or give any  guarantee,  indemnity  or  security in
                  respect of the obligations of any other person;

         14.8     enter into any death, retirement, profit sharing, bonus, share
                  option,  employee  incentive  plan  or  other  scheme  for the
                  benefit of the  officers  or  employees  of the Company or any
                  material  variation  (including any increase in the percentage
                  amount of the contributions) of any such scheme;

<PAGE>

         14.9     commence  any  legal or  arbitration  proceedings  other  than
                  routine debt collection;

         14.10    make any claim, disclaimer,  surrender, election or consent of
                  a material nature for tax purposes;

         14.11    make any early repayments of any of its indebtedness; or

         14.12    permit any power or authority of its Directors to be delegated
                  to an  executive  officer or  committee of Directors or to any
                  other person whatsoever.

15       MATTERS REQUIRING PREFERRED SHAREHOLDERS APPROVAL

         15.1     Unless this  Agreement  otherwise  provides,  the Company will
                  not,  and none of the  other  companies  in the Group (if any)
                  will do any of the  following,  without the prior  approval of
                  two thirds of the Preferred Shareholders:

                  (a)  issue, allot, redeem,  purchase or grant options over any
                       of  its  Shares,   debentures  or  other   securities  or
                       reorganise its share capital in any way except:

                       (i)  where the  number  of  Shares,  debentures  or other
                            securities  to  be  issued,  allotted,  redeemed  or
                            purchased  does  not  exceed,  within  any 12  month
                            period,   10%  of  the  total   number  of   Shares,
                            debentures or other securities of the same class;

                       (ii) in relation to an Employee Share Plan; or

                       (iii)in  relation to all  options  currently  on issue at
                            the Commencement Date;

                  (b)  pay or make any Dividend or other distribution  including
                       without  limiting the foregoing make any distribution out
                       of capital  profits or capital  reserves  (including  any
                       share premium account or capital redemption reserve fund)
                       except pursuant to the provisions of Clause 5.1;

                  (c)  amend  the  provisions  of its  Constitution  or pass any
                       resolution for winding up;

                  (d)  acquire  or make any  investment  in  another  company or
                       business;

                  (e)  change the nature or scope of its  business to a material
                       extent or commence  any  material  new business not being
                       ancillary or  incidental  to such  business as defined in
                       the Company's current Business Plan;

<PAGE>

                  (f)  merge or amalgamate with any person;

                  (g)  incur any material  research and development  expenditure
                       in excess of  $250,000 in any 12 month  period  otherwise
                       than in  accordance  with the  research  and  development
                       budget  agreed  to by the  Shareholders  for the  year in
                       question; or

                  (h)  modify or abrogate any rights for the time being attached
                       to any Shares.

         15.2     If the  Shareholders  (or any of them) have been  requested by
                  the Board or another  Shareholder  to provide their  approval,
                  consent or determination in relation to any matter relating to
                  the Company, and the request:

                  (a)  does not stipulate a time and date by which the approval,
                       consent  or  determination  is to be given  or made,  the
                       Shareholder must give or withhold its approval or consent
                       or make the determination  within 14 days after receiving
                       the request from the Board or other Shareholder; or

                  (b)  stipulates a time and date by which the approval, consent
                       or  determination is to be given or made, the Shareholder
                       must give or withhold its approval or consent or make the
                       determination within that timeframe.

                  If the  Shareholder  does not, it will be deemed to have given
                  its approval or consent, or made a favourable determination on
                  the expiry of the 14 day period or the stipulated timeframe.


         16       MANAGEMENT AND PERSONNEL

         16.1     Each Party,  including the Company, shall keep all information
                  which it obtains concerning the Business, affairs or assets of
                  the Company  strictly  confidential  and shall not,  and shall
                  procure that their respective officers,  employees, agents and
                  auditors do not,  without the prior written consent of all the
                  other  Parties,  disclose any of the above  information to any
                  third party except:

                  (a)  if  required  to make  such  disclosure  by any  court of
                       competent  jurisdiction or in order to enforce any rights
                       under this instrument in any proceedings;

                  (b)  pursuant to any court order;

                  (c)  pursuant  to any law or  regulation  having  the force of
                       law;

                  (d)  pursuant  to any  requirements  of the  Australian  Stock
                       Exchange Limited;

<PAGE>

                  (e)  in  circumstances  where the  information has come within
                       the public domain otherwise than by reason of a breach by
                       one of the Parties of the provisions of this Clause;

                  (f)  to a bona fide intending  purchaser of at least 5% of any
                       class of  Shares  or to a bona  fide  intending  director
                       provided such purchaser or director agrees to observe the
                       confidentiality provisions of this Clause;

                  (g)  in the normal and ordinary  course of the Business of the
                       Company;

                  (h)  pursuant to any other contract or legal  obligation  upon
                       the Company;

                  (i)  nothing in this  Clause  shall  prohibit a Director  from
                       providing information to his appointor; or

                  (j)  nothing in this Clause  shall  prohibit  any  Shareholder
                       from disclosing the information, on a confidential basis,
                       to employees or officers of any Related Body Corporate of
                       that Shareholder to the extent as is reasonably  required
                       to satisfy any  reporting  obligations  that Related Body
                       Corporate  has to the  ultimate  beneficial  owner of the
                       Shares.

         16.2     The  Company  shall  ensure that the  contract  of  employment
                  entered  into  with  all  employees  of the  Company  contains
                  confidentiality obligations in a form reasonably acceptable to
                  the  Preferred  Shareholders,  or if there is not such written
                  contract, that the employee executes a Confidentiality Deed.

         16.3     The  Company  shall  ensure that the  contract  of  employment
                  entered into with all Senior Employees  contains a restrictive
                  covenant in relation to future employment in a form reasonably
                  acceptable  to the Preferred  Shareholders  or, if there is no
                  such written  contract  that each Senior  Employee  executes a
                  restrictive  covenant in relation  to future  employment  in a
                  form reasonably acceptable to the Preferred Shareholders.

         16.4     The personnel  requirements  of the Company will be determined
                  by the Board.


17       SUBSCRIPTION COSTS

         17.1     Subject to Clause 17.2 being met,  the  Company  will bear all
                  reasonable  legal  expenses  of  the  Preferred   Shareholders
                  associated with the preparation, negotiation and completion of
                  this  Agreement  and  the  amendment  to the  Constitution  to
                  include the terms of issue of the Series A Preferred Shares.

<PAGE>

         17.2     On or before the  Commencement  Date,  each of the Company and
                  the Shareholders shall, where appropriate, duly and punctually
                  hold the meetings,  give the notices and otherwise comply with
                  all the requirements of RBML regarding compliance with Section
                  260B of the Corporations Law so that to the extent required by
                  RBML  any and all  financial  assistance,  as  referred  to in
                  Clause 17.1 given by the Company is not  prohibited by Section
                  260A of the Corporations Law.

         17.3     If the  Shareholders  do not approve  the giving of  financial
                  assistance  as referred to in Clause 17.1  pursuant to Section
                  260B of the Corporations  Law, the Shareholders  will bear, in
                  their Specified Proportions,  all reasonable legal expenses of
                  RBML   associated  with  the   preparation,   negotiation  and
                  completion  of  this   Agreement  and  the  amendment  to  the
                  Constitution.


18       INDEMNITY FROM PRAXIS USA

         Praxis  USA  indemnifies  and  agrees to keep  indemnified  each of the
         Shareholders and the Company against all proceedings,  claims, damages,
         costs, expenses, losses and liabilities of whatever nature which may be
         suffered, incurred, paid or sustained by any of the Shareholders or the
         Company whether directly or indirectly as a result of any claim, action
         or proceedings  brought by any shareholder of Praxis USA against Praxis
         USA or any of the  Shareholders  or  the  Company  in  relation  to the
         subscriptions  and transactions  contemplated by, or the conduct of the
         Business  in  accordance  with,  this  Agreement,   including   without
         limitation,  the Licence and Research & Development  Agreements and the
         Licence Agreements.


19       PUBLICITY

         19.1     No  public   announcement   of  the   holding   of  Shares  as
                  contemplated  in this  Agreement  shall  be made by any of the
                  Parties  otherwise  than  as a  joint  announcement  in a form
                  approved by all the Parties.

         19.2     Subject to Clause  19.1 and except to the extent  required  by
                  law or by the rules of any stock exchange, no Party shall make
                  any disclosure in relation to any other terms or conditions of
                  this Agreement.


20       NOTICES

         Any notice  required to be given under this  Agreement  by any Party to
         another shall be:

         20.1     in writing addressed to the address of the intended  recipient
                  shown in this Agreement  below or to such other address as has
                  been most recently  notified by the intended  recipient to the
                  Party giving the notice:

<PAGE>
                  IN THE CASE OF THE COMPANY:

                  Level 7, 60 Marcus Clarke Street
                  Canberra City, Australian Capital Territory 2601

                  Facsimile:

                  Attention:

                  IN THE CASE OF PRAXIS USA:

                  50 West Broadway, Salt Lake City, Utah,
                  United States of America 84101

                  Facsimile:

                  Attention:


                  IN THE CASE OF THE TRUSTEE:

                  39 Hunter Street, Sydney, New South Wales

                  Facsimile:  02 9221 1889

                  Attention: Senior Manager, Unit Trusts: Doug Browne


                  IN THE CASE OF RBML:

                  Level 10, 1 Collins Street, Melbourne, Victoria 3000

                  Facsimile:  03 9254 4940

                  Attention:  Dr Geoff Brooke


         20.2     signed by a person duly authorised by the sender; and

         20.3     deemed to have been given and served:

                  (a)  where despatched by hand, at the time delivery;

                  (b)  where  despatched  by  facsimile  transmission,  24 hours
                       after  the  time  recorded  on  the  transmission  report
                       unless:

                       (i)  within  those 24 hours the  intended  recipient  has
                            informed  the  sender  that  the   transmission  was
                            received in an incomplete or garbled form; or

                       (ii) the   transmission   result  report  of  the  sender
                            indicates a faulty or incomplete transmission; and

<PAGE>

                  (c)  where despatched by registered mail, on acknowledgment of
                       receipt by or on behalf of the recipient,

                  but  if  such  delivery  or  receipt  is  on a  day  on  which
                  commercial premises are not generally open for business in the
                  place of receipt or is later  than 4.00 p.m.  (local  time) on
                  any day,  the  notice  shall be deemed to have been  given and
                  served  on the  next  day on  which  commercial  premises  are
                  generally open for business in the place of receipt.


21       INCONSISTENCY WITH CONSTITUTION

         In the event that there is any inconsistency between this Agreement and
         the Constitution, this Agreement shall prevail.


22       FURTHER ASSURANCES

         Each Party shall take all such steps, execute all such documents and do
         all such acts and  things as may be  reasonably  required  by the other
         Parties to give effect to any of the transactions  contemplated by this
         Agreement.


23       NON-WAIVER

         Other  than as  otherwise  specified  in this  Agreement,  neither  the
         failure of any Party to enforce  at any time any of the  provisions  of
         this Agreement nor the granting of any time or other  indulgence  shall
         be  construed  as a waiver  of that  provision  or of the right of that
         Party thereafter to enforce that or any other provision.


24       COSTS

         Other than as otherwise specified in this Agreement,  the Parties shall
         bear their own costs arising out of the  preparation  of this Agreement
         save that the  Company  shall  bear any stamp duty  chargeable  on this
         Agreement  and on any  instruments  (other  than a transfer  of Shares)
         required to be entered into pursuant to this  Agreement and the Company
         indemnifies  the other Parties against the liability for all such stamp
         duty.


25       AMENDMENT

         This  Agreement  may not be  amended  except by the  unanimous  written
         consent of all Parties.

26       TRUSTEES LIMITATION OF LIABILITY PROTECTION CLAUSE

         26.1     The Trustee enters into this Agreement only in its capacity as
                  trustee  of the Trust and in no other  capacity.  A  liability
                  arising under

<PAGE>
                  or in connection  with this Agreement is limited to and can be
                  enforced  against the  Trustee  only to the extent to which it
                  can be satisfied out of property of the Trust out of which the
                  Trustee  is  actually  indemnified  for  the  liability.  This
                  limitation  of the  Trustee's  liability  applies  despite any
                  other   provision  of  this   Agreement  and  extends  to  all
                  liabilities   and  obligations  of  the  Trustee  in  any  way
                  connected   with  any   representation,   warranty,   conduct,
                  omission, agreement or transaction related to this Agreement.

         26.2     The parties  other than the Trustee may not sue the Trustee in
                  any  capacity  other than as  trustee of the Trust,  including
                  seek the  appointment  of a receiver  (except in  relation  to
                  property of the Trust), a liquidator,  an administrator or any
                  similar  person to the  Trustee  or prove in any  liquidation,
                  administration  or  arrangement  of or  affecting  the Trustee
                  (except in relation to property of the Trust).

         26.3     The  provisions  of this  Clause  26  shall  not  apply to any
                  obligation  or  liability of the Trustee to the extent that it
                  is not satisfied because under the Trust Deed establishing the
                  Trust  or by  operation  of law  there is a  reduction  in the
                  extent of the Trustee's  indemnification  out of the assets of
                  the Trust, as a result of the Trustee's  fraud,  negligence or
                  breach of trust.

         26.4     It is  acknowledged  that RBML as the  manager of the Trust is
                  responsible  under the Trust Deed  establishing  the Trust for
                  performing  a variety of  obligations  relating  to the Trust,
                  including  under this  Agreement.  No act or  omission  of the
                  Trustee   (including  any  related   failure  to  satisfy  its
                  obligations or breach of representation or warranty under this
                  Agreement) will be considered  fraud,  negligence or breach of
                  trust of the  Trustee  for the  purpose of this Clause 26.3 to
                  the  extent  to  which  the  act or  omission  was  caused  or
                  contributed  to by any  failure  by the  manager  or any other
                  person to fulfil its  obligations  relating to the Trust or by
                  any other act or omission of the manager or any other person.


27       COUNTERPARTS

         This Agreement may be executed in any number of  counterparts,  each of
         which  when so  executed  shall be  deemed to be an  original  and such
         counterparts together shall constitute one and the same instrument.

28       GOVERNING LAW

         This Agreement  shall be governed by and interpreted in accordance with
         the laws for the time being in force in the State of Victoria  and each
         party  submits to the  non-exclusive  jurisdiction  of the Courts of or
         exercising jurisdiction in that State.


<PAGE>


IN WITNESS  WHEREOF the parties have executed this Agreement on the date written
above.




THE COMMON SEAL of PRAXIS                    )
PHARMACEUTICALS AUSTRALIA PTY                )
LIMITED (ACN 082 811 630) was hereto         )
affixed in accordance with its Constitution  )
in the presence of:                          )

/s/ William B. Cowden                        Director

William B. Cowden                            Name of Director (Print)

/s/ Brett Charlton                           Director/Secretary

Brett Charlton                               Name of Director/Secretary (Print)




EXECUTED  by PRAXIS                          )
PHARMACEUTICALS INC. by its                  )
authorised officer in the presence of:       )
                                             )

/s/ William B. Cowden                        Authorised Officer

William B. Cowden                            Name of Authorised Officer (Print)

CEO                                          Title




EXECUTED BY PERPETUAL
TRUSTEES NOMINEES LIMITED
(ACN 000 341 533)

PERPETUAL TRUSTEES NOMINEES LIMITED (CAN
000  341  533)  By  its   Attorneys  who
declare  that  they  have no  notice  of
revocation  of  the  Power  of  Attorney
under which this document is signed.


THE COMMON SEAL of ROTHSCHILD                )
BIOSCIENCE MANAGERS LIMITED                  )
(ACN 072 515 247) was hereto affixed in      )
accordance with its Constitution in the      )
presence of:                                 )

/s/ G.C.D. Brooke                            Director

G.C.D. Brooke                                Name of Director (Print)


/s/ M.D. Pickering                           /Secretary

M.D. Pickering                               Name of /Secretary (Print)







<PAGE>







                                  EXHIBIT 10.5

                             1999 STOCK OPTION PLAN


<PAGE>
                           PRAXIS PHARMACEUTICALS INC.
                             1999 STOCK OPTION PLAN

1.       PURPOSE; EFFECTIVENESS OF THE PLAN.

         (a)      The purpose of this Plan is to advance the interests of the
                  Company and its stockholders by helping the Company obtain and
                  retain the services of employees, officers, consultants, and
                  directors, upon whose judgment, initiative and efforts the
                  Company is substantially dependent, and to provide those
                  persons with further incentives to advance the interests of
                  the Company.

         (b)      This Plan will become effective on the date of its adoption by
                  the Board, provided the Plan is approved by the stockholders
                  of the Company (excluding holders of shares of Stock issued by
                  the Company pursuant to the exercise of options granted under
                  this Plan) within twelve months before or after that date. If
                  the Plan is not so approved by the stockholders of the
                  Company, any options granted under this Plan will be rescinded
                  and will be void. This Plan will remain in effect until it is
                  terminated by the Board or the Committee (as defined
                  hereafter) under section 9 hereof, except that no ISO (as
                  defined herein) will be granted after the tenth anniversary of
                  the date of this Plan's adoption by the Board. This Plan will
                  be governed by, and construed in accordance with, the laws of
                  the State of Utah.

2.       CERTAIN DEFINITIONS.

         Unless the context otherwise requires, the following defined terms
         (together with other capitalized terms defined elsewhere in this Plan)
         will govern the construction of this Plan, and of any stock option
         agreements entered into pursuant to this Plan:

         (a)      "10% Stockholder" means a person who owns, either directly or
                  indirectly by virtue of the ownership attribution provisions
                  set forth in Section 424(d) of the Code at the time he or she
                  is granted an Option, stock possessing more than ten percent
                  (10%) of the total combined voting power or value of all
                  classes of stock of the Company and/or of its subsidiaries;

         (b)      "1933  Act"  means  the  federal  Securities  Act of 1933,  as
                  amended;

         (c)      "Board" means the Board of Directors of the Company;

         (d)      "Called for under an Option," or words to similar effect,
                  means issuable pursuant to the exercise of an Option;

         (e)      "Code" means the Internal Revenue Code of 1986, as amended
                  (references herein to Sections of the Code are intended to
                  refer to Sections of the Code as enacted at the time of this
                  Plan's adoption by the Board and as subsequently amended, or
                  to any substantially similar successor provisions of the Code
                  resulting from recodification, renumbering or otherwise);

<PAGE>



         (f)      "Committee" means a committee of two or more Disinterested
                  Directors, appointed by the Board, to administer and interpret
                  this Plan; provided that the term "Committee" will refer to
                  the Board during such times as no Committee is appointed by
                  the Board;

         (g)      "Company" means Praxis Pharmaceuticals Inc., a Utah
                  corporation;

         (h)      "Disability" has the same meaning as "permanent and total
                  disability," as defined in Section 22(e)(3) of the Code;

         (i)      "Disinterested Director" means a member of the Board who is
                  not during the period of one year prior to his or her service
                  as an administrator of the Plan, or during the period of such
                  service, granted or awarded Stock, options to acquire Stock,
                  or similar equity securities of the Company under this Plan or
                  any similar plan of the Company, other than the grant of a
                  Formula Option pursuant to section 6(m) of this Plan;

         (j)      "Eligible Participants" means persons who, at a particular
                  time, are employees, officers, consultants, or directors of
                  the Company or its subsidiaries;

         (k)      "Fair Market Value" means, with respect to the Stock and as of
                  the date an ISO or a Formula Option is granted hereunder, the
                  market price per share of such Stock determined by the
                  Committee, consistent with the requirements of Section 422 of
                  the Code and to the extent consistent therewith, as follows:

                  (i)      If the Stock was traded on a stock exchange on the
                           date in question, then the Fair Market Value will be
                           equal to the closing price reported by the applicable
                           composite-transactions report for such date;

                  (ii)     If the Stock was traded over-the-counter on the date
                           in question and was classified as a national market
                           issue, then the Fair Market Value will be equal to
                           the last-transaction price quoted by the NASDAQ
                           system for such date;

                  (iii)    If the Stock was traded over-the-counter on the date
                           in question but was not classified as a national
                           market issue, then the Fair Market Value will be
                           equal to the average of the last reported
                           representative bid and asked prices quoted by the
                           NASDAQ system for such date; and

                  (iv)     If none of the foregoing provisions is applicable,
                           then the Fair Market Value will be determined by the
                           Committee in good faith on such basis as it deems
                           appropriate.

         (l)      "Formula Option" means an NSO granted to members of the
                  Committee pursuant to section 6(m) hereof;

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 2

<PAGE>



         (m)      "ISO" has the same meaning as "incentive stock option," as
                  defined in Section 422 of the Code;

         (n)      "Just Cause Termination" means a termination by the Company of
                  an Optionee's employment by and/or service to the Company (or
                  if the Optionee is a director, removal of the Optionee from
                  the Board by action of the stockholders or, if permitted by
                  applicable law and the by-laws of the Company, the other
                  directors), in connection with the good faith determination of
                  the Company's board of directors (or of the Company's
                  stockholders if the Optionee is a director and the removal of
                  the Optionee from the Board is by action of the stockholders,
                  but in either case excluding the vote of the Optionee if he or
                  she is a director or a stockholder) that the Optionee has
                  engaged in any acts involving dishonesty or moral turpitude or
                  in any acts that materially and adversely affect the business,
                  affairs or reputation of the Company or its subsidiaries;

         (o)      "NSO" means any option granted under this Plan whether
                  designated by the Committee as a "non-qualified stock option,"
                  a "non-statutory stock option" or otherwise, other than an
                  option designated by the Committee as an ISO, or any option so
                  designated but which, for any reason, fails to qualify as an
                  ISO pursuant to Section 422 of the Code and the rules and
                  regulations thereunder;

         (p)      "Option" means an option granted pursuant to this Plan
                  entitling the option holder to acquire shares of Stock issued
                  by the Company pursuant to the valid exercise of the option;

         (q)      "Option Agreement" means an agreement between the Company and
                  an Optionee, in form and substance satisfactory to the
                  Committee in its sole discretion, consistent with this Plan;

         (r)      "Option Price" with respect to any particular Option means the
                  exercise price at which the Optionee may acquire each share of
                  the Option Stock called for under such Option;

         (s)      "Option Stock" means Stock issued or issuable by the Company
                  pursuant to the valid exercise of an Option;

         (t)      "Optionee" means an Eligible Participant to whom Options are
                  granted hereunder, and any transferee thereof pursuant to a
                  Transfer authorized under this Plan;

         (u)      "Plan" means this 1999 Stock Option Plan of the Company;

         (v)      "QDRO" has the same meaning as "qualified domestic relations
                  order" as defined in Section 414(p) of the Code;

         (w)      "Stock" means shares of the Company's Common Stock, $0.001 par
                  value;

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 3

<PAGE>



         (x)      "Subsidiary" has the same meaning as "Subsidiary Corporation"
                  as defined in Section 424(f) of the Code;

         (y)      "Transfer," with respect to Option Stock, includes, without
                  limitation, a voluntary or involuntary sale, assignment,
                  transfer, conveyance, pledge, hypothecation, encumbrance,
                  disposal, loan, gift, attachment or levy of such Option Stock,
                  including without limitation an assignment for the benefit of
                  creditors of the Optionee, a transfer by operation of law,
                  such as a transfer by will or under the laws of descent and
                  distribution, an execution of judgment against the Option
                  Stock or the acquisition of record or beneficial ownership
                  thereof by a lender or creditor, a transfer pursuant to a
                  QDRO, or to any decree of divorce, dissolution or separate
                  maintenance, any property settlement, any separation agreement
                  or any other agreement with a spouse (except for estate
                  planning purposes) under which a part or all of the shares of
                  Option Stock are transferred or awarded to the spouse of the
                  Optionee or are required to be sold; or a transfer resulting
                  from the filing by the Optionee of a petition for relief, or
                  the filing of an involuntary petition against such Optionee,
                  under the bankruptcy laws of the United States or of any other
                  nation.

3.       ELIGIBILITY.

         The Company may grant Options under this Plan only to persons who are
         Eligible Participants as of the time of such grant. Subject to the
         provisions of sections 4(d), 5 and 6 hereof, there is no limitation on
         the number of Options that may be granted to an Eligible Participant.

4.       ADMINISTRATION.

         (a)      COMMITTEE. The Committee, if appointed by the Board, will
                  administer this Plan. If the Board, in its discretion, does
                  not appoint such a Committee, the Board itself will administer
                  this Plan and take such other actions as the Committee is
                  authorized to take hereunder; provided that the Board may take
                  such actions hereunder in the same manner as the Board may
                  take other actions under the Company's Articles of
                  Incorporation and By-laws generally.

         (b)      AUTHORITY AND DISCRETION OF COMMITTEE. The Committee will have
                  full and final authority in its discretion, at any time and
                  from time to time, subject only to the express terms,
                  conditions and other provisions of the Company's Articles of
                  incorporation, by-laws and this Plan, and the specific
                  limitations on such discretion set forth herein:

                  (i)      to select and approve the persons who will be granted
                           Options under this Plan from among the Eligible
                           Participants, and to grant to any person so selected
                           one or more Options to purchase such number of shares
                           of Option Stock as the Committee may determine;

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 4

<PAGE>



                  (ii)     to determine the period or periods of time during
                           which Options may be exercised, the Option Price and
                           the duration of such Options, and other matters to be
                           determined by the Committee in connection with
                           specific Option grants and Options Agreements as
                           specified under this Plan;

                  (iii)    to interpret this Plan, to prescribe, amend and
                           rescind rules and regulations relating to this Plan,
                           and to make all other determinations necessary or
                           advisable for the operation and administration of
                           this Plan; and

                  (iv)     to delegate all or a portion of its authority under
                           subsections (i) and (ii) of this section 4(b) to one
                           or more directors of the Company who are executive
                           officers of the Company, but only in connection with
                           Options granted to Eligible Participants who are not
                           subject to the reporting and liability provisions of
                           Section 16 of the Securities Exchange Act of 1934, as
                           amended, and the rules and regulations thereunder,
                           and subject to such restrictions and limitations
                           (such as the aggregate number of shares of Option
                           Stock called for by such Options that may be granted)
                           as the Committee may decide to impose on such
                           delegate directors.

         (c)      LIMITATION ON AUTHORITY. Notwithstanding the foregoing, or any
                  other provision of this Plan, the Committee will have no
                  authority:

                  (i)      to grant Options to any of its members, whether or
                           not approved by the Board; and

                  (ii)     to determine any matters, or exercise any discretion,
                           in connection with the Formula Options under section
                           6(m) hereof, to the extent that the power to make
                           such determinations or to exercise such discretion
                           would cause one or more members of the Committee no
                           longer to be "Disinterested Directors" within the
                           meaning of section 2(i) above.

         (d)      DESIGNATION OF OPTIONS. Except as otherwise provided herein,
                  the Committee will designate any Option granted hereunder
                  either as an ISO or as an NSO. To the extent that the Fair
                  Market Value (determined at the time the Option is granted) of
                  Stock with respect to which all ISOs are exercisable for the
                  first time by any individual during any calendar year
                  (pursuant to this Plan and all other plans of the Company
                  and/or its subsidiaries) exceeds $100,000, such option will be
                  treated as an NSO. Notwithstanding the general eligibility
                  provisions of section 3 hereof, the Committee may grant ISOs
                  only to persons who are employees of the Company and/or its
                  subsidiaries.

         (e)      OPTION AGREEMENTS. Options will be deemed granted hereunder
                  only upon the execution and delivery of an Option Agreement by
                  the Optionee and a duly authorized officer of the Company.
                  Options will not be deemed granted hereunder merely upon the
                  authorization of such grant by the Committee.

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 5

<PAGE>



5.       SHARES RESERVED FOR OPTIONS.

         (a)      OPTION POOL. The aggregate number of shares of Option Stock
                  that may be issued pursuant to the exercise of Options granted
                  under this Plan initially will not exceed One Million Six
                  Hundred Ninety-Eight Thousand Three Hundred Thirty (1,698,330)
                  (the "Option Pool"), provided that such number automatically
                  shall be adjusted annually on the beginning of the Company's
                  fiscal year to a number equal to 15% of the number of shares
                  of Stock of the Company outstanding at the end of the
                  Company's last completed fiscal year, or 1,698,330 shares,
                  whichever is greater, and provided further that such number
                  will be increased by the number of shares of Option Stock that
                  the Company subsequently may reacquire through repurchase or
                  otherwise. Shares of Option Stock that would have been
                  issuable pursuant to Options, but that are no longer issuable
                  because all or part of those Options have terminated or
                  expired, will be deemed not to have been issued for purposes
                  of computing the number of shares of Option Stock remaining in
                  the Option Pool and available for issuance.

         (b)      ADJUSTMENTS UPON CHANGES IN STOCK. In the event of any change
                  in the outstanding Stock of the Company as a result of a stock
                  split, reverse stock split, stock dividend, recapitalization,
                  combination or reclassification, appropriate proportionate
                  adjustments will be made in:

                  (i)      the aggregate number of shares of Option Stock in the
                           Option Pool that may be issued pursuant to the
                           exercise of Options granted hereunder;

                  (ii)     the Option Price and the number of shares of Option
                           Stock called for in each outstanding Option granted
                           hereunder; and

                  (iii)    other rights and matters determined on a per share
                           basis under this Plan or any Option Agreement
                           hereunder. Any such adjustments will be made only by
                           the Board, and when so made will be effective,
                           conclusive and binding for all purposes with respect
                           to this Plan and all Options then outstanding. No
                           such adjustments will be required by reason of the
                           issuance or sale by the Company for cash or other
                           consideration of additional shares of its Stock or
                           securities convertible into or exchangeable for
                           shares of its Stock.



6.       TERMS OF STOCK OPTION AGREEMENTS.

         Each Option granted pursuant to this Plan will be evidenced by an
         agreement (an "Option Agreement") between the Company and the person to
         whom such Option is granted, in form and substance satisfactory to the
         Committee in its sole discretion, consistent with

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 6

<PAGE>



         this Plan. Without limiting the foregoing, each Option Agreement
         (unless otherwise stated therein) will be deemed to include the
         following terms and conditions:

         (a)      COVENANTS OF OPTIONEE. At the discretion of the Committee, the
                  person to whom an Option is granted hereunder, as a condition
                  to the granting of the Option, must execute and deliver to the
                  Company a confidential information agreement approved by the
                  Committee. Nothing contained in this Plan, any Option
                  Agreement or in any other agreement executed in connection
                  with the granting of an Option under this Plan will confer
                  upon any Optionee any right with respect to the continuation
                  of his or her status as an employee of, consultant or
                  independent contractor to, or director of, the Company or its
                  subsidiaries.

         (b)      VESTING PERIODS. Except as otherwise provided herein, each
                  Option Agreement may specify the period or periods of time
                  within which each Option or portion thereof will first become
                  exercisable (the "Vesting Period") with respect to the total
                  number of shares of Option Stock called for thereunder (the
                  "Total Award Option Stock"). Such Vesting Periods will be
                  fixed by the Committee in its discretion, and may be
                  accelerated or shortened by the Committee in its discretion.

                  Unless the Option Agreement executed by an Optionee expressly
                  otherwise provides and except as set forth herein, the right
                  to exercise an Option granted hereunder will be subject to the
                  following Vesting Periods, subject to the Optionee continuing
                  to be an Eligible Participant and the occurrence of any other
                  event (including the passage of time) that would result in the
                  cancellation or termination of the Option:

                  (i)      no portion of the Option will be exercisable prior to
                           the expiration of six (6) months after the date of
                           grant set forth in the Option Agreement; and

                  (ii)     such additional vesting periods as may be determined
                           by the Committee in its sole discretion.

         (c)      EXERCISE OF THE OPTION.

                  (i)      MECHANICS AND NOTICE. An Option may be exercised to
                           the extent exercisable (1) by giving written notice
                           of exercise to the Company, specifying the number of
                           full shares of Option Stock to be purchased and
                           accompanied by full payment of the Option Price
                           thereof and the amount of withholding taxes pursuant
                           to subsection 6(c)(ii) below; and (2) by giving
                           assurances satisfactory to the Company that the
                           shares of Option Stock to be purchased upon such
                           exercise are being purchased for investment and not
                           with a view to resale in connection with any
                           distribution of such shares in violation of the 1933
                           Act; provided, however, that in the event the Option
                           Stock called for under the Option is registered under
                           the 1933 Act, or in the event resale of such Option
                           Stock

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 7

<PAGE>



                           without such registration would otherwise be
                           permissible, this second condition will be
                           inoperative if, in the opinion of counsel for the
                           Company, such condition is not required under the
                           1933 Act, or any other applicable law, regulation or
                           rule of any governmental agency.

                  (ii)     WITHHOLDING TAXES. As a condition to the issuance of
                           the shares of Option Stock upon full or partial
                           exercise of an NSO granted under this Plan, the
                           Optionee will pay to the Company in cash, or in such
                           other form as the Committee may determine in its
                           discretion, the amount of the Company's tax
                           withholding liability required in connection with
                           such exercise. For purposes of this subsection
                           6(c)(ii), "tax withholding liability" will mean all
                           federal and state income taxes, social security tax,
                           and any other taxes applicable to the compensation
                           income arising from the transaction required by
                           applicable law to be withheld by the Company.

         (d)      PAYMENT OF OPTION PRICE. Each Option Agreement will specify
                  the Option Price with respect to the exercise of Option Stock
                  thereunder, to be fixed by the Committee in its discretion,
                  but in no event will the Option Price for an ISO granted
                  hereunder be less than the Fair Market Value (or, in case the
                  Optionee is a 10% Stockholder, one hundred ten percent (110%)
                  of such Fair Market Value) of the Option Stock at the time
                  such ISO is granted, and in no event will the Option Price for
                  an NSO granted hereunder be less than eighty-five percent
                  (85%) of Fair Market Value. The Option Price will be payable
                  to the Company in United States dollars in cash or by check
                  or, such other legal consideration as may be approved by the
                  Committee, in its discretion.

                  (i)      For example, the Committee, in its discretion, may
                           permit a particular Optionee to pay all or a portion
                           of the Option Price, and/or the tax withholding
                           liability set forth in subsection 6(c)(ii) above,
                           with respect to the exercise of an Option either by
                           surrendering shares of Stock already owned by such
                           Optionee or by withholding shares of Option Stock,
                           provided that the Committee determines that the fair
                           market value of such surrendered Stock or withheld
                           Option Stock is equal to the corresponding portion of
                           such Option Price and/or tax withholding liability,
                           as the case may be, to be paid for therewith.

                  (ii)     If the Committee permits an Optionee to pay any
                           portion of the Option Price and/or tax withholding
                           liability with shares of Stock with respect to the
                           exercise of an Option (the "Underlying Option") as
                           provided in subsection 6(d)(i) above, then the
                           Committee, in its discretion, may grant to such
                           Optionee (but only if Optionee remains an Eligible
                           Participant at that time) additional NSOs, the number
                           of shares of Option Stock called for thereunder to be
                           equal to all or a portion of the Stock so surrendered
                           or withheld (a "Replacement Option"). Each
                           Replacement Option will be evidenced by an Option
                           Agreement. Unless otherwise set forth therein,

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 8

<PAGE>



                           each Replacement Option will be immediately
                           exercisable upon such grant (without any Vesting
                           Period) and will be coterminous with the Underlying
                           Option. The Committee, in its sole discretion, may
                           establish such other terms and conditions for
                           Replacement Options as it deems appropriate.

         (e)      TERMINATION OF THE OPTION. Except as otherwise provided
                  herein, each Option Agreement will specify the period of time,
                  to be fixed by the Committee in its discretion, during which
                  the Option granted therein will be exercisable, not to exceed
                  ten years from the date of grant in the case of an ISO (the
                  "Option Period"); provided that the Option Period will not
                  exceed five years from the date of grant in the case of an ISO
                  granted to a 10% Stockholder. To the extent not previously
                  exercised, each Option will terminate upon the expiration of
                  the Option Period specified in the Option Agreement; provided,
                  however, that each such Option will terminate, if earlier:

                  (i)      ninety days after the date that the Optionee ceases
                           to be an Eligible Participant for any reason, other
                           than by reason of death or disability or a Just Cause
                           Termination;

                  (ii)     twelve months after the date that the Optionee ceases
                           to be an Eligible Participant by reason of such
                           person's death or disability; or

                  (iii)    immediately as of the date that the Optionee ceases
                           to be an Eligible Participant by reason of a Just
                           Cause Termination.

                  In the event of a sale or all or substantially all of the
                  assets of the Company, or a merger or consolidation or other
                  reorganization in which the Company is not the surviving
                  corporation, or in which the Company becomes a subsidiary of
                  another corporation (any of the foregoing events, a "Corporate
                  Transaction"), then notwithstanding anything else herein, the
                  right to exercise all then outstanding Options will vest
                  immediately prior to such Corporate Transaction and will
                  terminate immediately after such Corporate Transaction;
                  provided, however, that if the Board, in its sole discretion,
                  determines that such immediate vesting of the right to
                  exercise outstanding Options is not in the best interests of
                  the Company, then the successor corporation must agree to
                  assume the outstanding Options or substitute therefor
                  comparable options of such successor corporation or a parent
                  or subsidiary of such successor corporation.

         (f)      OPTIONS NONTRANSFERABLE. No Option will be transferable by the
                  Optionee otherwise than by will or the laws of descent and
                  distribution, or in the case of an NSO, pursuant to a QDRO.
                  During the lifetime of the Optionee, the Option will be
                  exercisable only by him or her, or the transferee of an NSO if
                  it was transferred pursuant to a QDRO.


Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 9

<PAGE>



         (g)      QUALIFICATION OF STOCK. The right to exercise an Option will
                  be further subject to the requirement that if at any time the
                  Board determines, in its discretion, that the listing,
                  registration or qualification of the shares of Option Stock
                  called for thereunder upon any securities exchange or under
                  any state or federal law, or the consent or approval of any
                  governmental regulatory authority, is necessary or desirable
                  as a condition of or in connection with the granting of such
                  Option or the purchase of shares of Option Stock thereunder,
                  the Option may not be exercised, in whole or in part, unless
                  and until such listing, registration, qualification, consent
                  or approval is effected or obtained free of any conditions not
                  acceptable to the Board, in its discretion.

         (h)      ADDITIONAL RESTRICTIONS ON TRANSFER. By accepting Options
                  and/or Option Stock under this Plan, the Optionee will be
                  deemed to represent, warrant and agree as follows:

                  (i)      SECURITIES ACT OF 1933. The Optionee understands that
                           the shares of Option Stock have not been registered
                           under the 1933 Act, and that such shares are not
                           freely tradeable and must be held indefinitely unless
                           such shares are either registered under the 1933 Act
                           or an exemption from such registration is available.
                           The Optionee understands that the Company is under no
                           obligation to register the shares of Option Stock.

                  (ii)     OTHER APPLICABLE LAWS. The Optionee further
                           understands that Transfer of the Option Stock
                           requires full compliance with the provisions of all
                           applicable laws.

                  (iii)    INVESTMENT INTENT. Unless a registration statement is
                           in effect with respect to the sale of Option Stock
                           obtained through exercise of Options granted
                           hereunder: (1) Upon exercise of any Option, the
                           Optionee will purchase the Option Stock for his or
                           her own account and not with a view to distribution
                           within the meaning of the 1933 Act, other than as may
                           be effected in compliance with the 1933 Act and the
                           rules and regulations promulgated thereunder; (2) no
                           one else will have any beneficial interest in the
                           Option Stock; and (3) he or she has no present
                           intention of disposing of the Option Stock at any
                           particular time.

         (i)      COMPLIANCE WITH LAW. Notwithstanding any other provision of
                  this Plan, Options may be granted pursuant to this Plan, and
                  Option Stock may be issued pursuant to the exercise thereof by
                  an Optionee, only after there has been compliance with all
                  applicable federal and state securities laws, and all of the
                  same will be subject to this overriding condition. The Company
                  will not be required to register or qualify Option Stock with
                  the Securities and Exchange Commission or any State agency,
                  except that the Company will register with, or as required by
                  local law, file for and secure an exemption from such
                  registration requirements from, the applicable

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 10

<PAGE>



                  securities administrator and other officials of each
                  jurisdiction in which an Eligible Participant would be granted
                  an Option hereunder prior to such grant.

         (j)      STOCK CERTIFICATES. Certificates representing the Option Stock
                  issued pursuant to the exercise of Options will bear all
                  legends required by law and necessary to effectuate this
                  Plan's provisions. The Company may place a "stop transfer"
                  order against shares of the Option Stock until all
                  restrictions and conditions set forth in this Plan and in the
                  legends referred to in this section 6(k) have been complied
                  with.

         (k)      NOTICES. Any notice to be given to the Company under the terms
                  of an Option Agreement will be addressed to the Company at its
                  principal executive office, Attention: Corporate Secretary, or
                  at such other address as the Company may designate in writing.
                  Any notice to be given to an Optionee will be addressed to the
                  Optionee at the address provided to the Company by the
                  Optionee. Any such notice will be deemed to have been duly
                  given if and when enclosed in a properly sealed envelope,
                  addressed as aforesaid, registered and deposited, postage and
                  registry fee prepaid, in a post office or branch post office
                  regularly maintained

         (l)      OTHER PROVISIONS. The Option Agreement may contain such other
                  terms, provisions and conditions, including such special
                  forfeiture conditions, rights of repurchase, rights of first
                  refusal and other restrictions on Transfer of Option Stock
                  issued upon exercise of any Options granted hereunder, not
                  inconsistent with this Plan, as may be determined by the
                  Committee in its sole discretion.

         (m)      FORMULA OPTIONS. [Reserved for future consideration]

7.       PROCEEDS FROM SALE OF STOCK.

         Cash proceeds from the sale of shares of Option Stock issued from time
         to time upon the exercise of Options granted pursuant to this Plan will
         be added to the general funds of the Company and as such will be used
         from time to time for general corporate purposes.

8.       MODIFICATION, EXTENSION AND RENEWAL OF OPTIONS.

         Subject to the terms and conditions and within the limitations of this
         Plan, and except with respect to Formula Options, the Committee may
         modify, extend or renew outstanding Options granted under this Plan, or
         accept the surrender of outstanding Options (to the extent not
         theretofore exercised) and authorize the granting of new Options in
         substitution therefor (to the extent not theretofore exercised).
         Notwithstanding the foregoing, however, no modification of any Option
         will, without the consent of the holder of the Option, alter or impair
         any rights or obligations under any Option theretofore granted under
         this Plan.

9.       AMENDMENT AND DISCONTINUANCE.

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 11

<PAGE>


         The Board may amend, suspend or discontinue this Plan at any time or
         from time to time; provided that no action of the Board will cause ISOs
         granted under this Plan not to comply with Section 422 of the Code
         unless the Board specifically declares such action to be made for that
         purpose and provided further that no such action may, without the
         approval of the stockholders of the Company, materially increase (other
         than by reason of an adjustment pursuant to section 5(b) hereof) the
         maximum aggregate number of shares of Option Stock in the Option Pool
         that may be issued under Options granted pursuant to this Plan or
         materially increase the benefits accruing to Plan participants or
         materially modify eligibility requirements for the participants.
         Provided, further, that the provisions of section 6(m) hereof may not
         be amended more often than once during any six (6) month period, other
         than to comport with changes in the Code, the Employee Retirement
         Income Security Act, or the rules and regulations thereunder. Moreover,
         no such action may alter or impair any Option previously granted under
         this Plan without the consent of the holder of such Option.

10.      PLAN COMPLIANCE WITH RULE 16B-3.

         With respect to persons subject to Section 16 of the Securities
         Exchange Act of 1934, transactions under this plan are intended to
         comply with all applicable conditions of Rule 16b-3 or its successors
         under the 1934 Act. To the extent any provision of the plan or action
         by the plan administrators fails so to comply, it shall be deemed null
         and void, to the extent permitted by law and deemed advisable by the
         plan administrators.

11.      COPIES OF PLAN.

         A copy of this Plan will be delivered to each Optionee at or before the
         time he or she executes an Option Agreement.

 ***
Date Plan Adopted by Board of Directors:    July 8, 1999
Date Plan Approved by Stockholders:         August 30, 1999

Praxis Pharmaceuticals Inc. 1999 Stock Option Plan - Page 12

<PAGE>







                                   EXHIBIT 21

                         SUBSIDIARIES OF THE REGISTRANT


<PAGE>
                         SUBSIDIARIES OF THE REGISTRANT

Praxis  Pharmaceuticals,  Inc., a Nevada company.

Praxis Pharmaceuticals Australia Pty. Ltd., an Austalian company.

<PAGE>


                                   EXHIBIT 27

                             FINANCIAL DATA SCHEDULE


<PAGE>


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
THE SCHEDULE CONTAINS SUMMARY FINANCIAL  INFORMATION  EXTRACTED FROM THE AUDITED
FINANCIAL STATEMENTS FOR THE YEAR ENDED MAY 31, 1999 AND THE UNAUDITED FINANCIAL
STATEMENTS  FOR THE THREE MONTHS ENDED AUGUST 31, 1999,  AND THE NOTES  THERETO,
WHICH MAY BE FOUND ON PAGES F-1 THROUGH F-19 OF THE COMPANY'S FORM 10-SB, AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER>                                   1
<CURRENCY>                                     U.S. DOLLARS

<S>                             <C>                         <C>
<PERIOD-TYPE>                   3-MOS                       YEAR
<FISCAL-YEAR-END>                              MAY-31-2000            MAY-31-1999
<PERIOD-START>                                 JUN-01-1999            JUN-01-1998
<PERIOD-END>                                   AUG-31-1999            MAY-31-1999
<EXCHANGE-RATE>                                1                      1
<CASH>                                         36,945                 103,513
<SECURITIES>                                   0                      0
<RECEIVABLES>                                  0                      0
<ALLOWANCES>                                   0                      0
<INVENTORY>                                    0                      0
<CURRENT-ASSETS>                               36,945                 103,513
<PP&E>                                         0                      0
<DEPRECIATION>                                 0                      0
<TOTAL-ASSETS>                                 36,945                 103,513
<CURRENT-LIABILITIES>                          185,997                159,910
<BONDS>                                        0                      0
                          0                      0
                                    0                      0
<COMMON>                                       667,473                637,473
<OTHER-SE>                                     (816,525)              (693,870)
<TOTAL-LIABILITY-AND-EQUITY>                   36,945                 103,513
<SALES>                                        0                      0
<TOTAL-REVENUES>                               0                      0
<CGS>                                          0                      0
<TOTAL-COSTS>                                  0                      0
<OTHER-EXPENSES>                               92,655                 530,574
<LOSS-PROVISION>                               0                      0
<INTEREST-EXPENSE>                             0                      0
<INCOME-PRETAX>                                (92,655)               (530,574)
<INCOME-TAX>                                   0                      0
<INCOME-CONTINUING>                            (92,655)               (530,574)
<DISCONTINUED>                                 0                      0
<EXTRAORDINARY>                                0                      0
<CHANGES>                                      0                      0
<NET-INCOME>                                   (92,655)               (530,574)
<EPS-BASIC>                                  (0.01)                 (0.07)
<EPS-DILUTED>                                  (0.01)                 (0.07)



</TABLE>


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