MUNICIPAL INVESTMENT TR FD MULTISTATE SER 416 DEF ASSET FDS
S-6, 2000-05-31
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     As filed with the Securities and Exchange Commission on May 31, 2000
                                                 Registration No. 333-
===============================================================================

                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549
                            -----------------------

                                   FORM S-6
                            -----------------------


               FOR REGISTRATION UNDER THE SECURITIES ACT OF 1933
                    OF SECURITIES OF UNIT INVESTMENT TRUSTS
                           REGISTERED ON FORM N-8B-2

                             --------------------

  A.  Exact Name of Trust:
                        MUNICIPAL INVESTMENT TRUST FUND
                            MULTISTATE SERIES-416
                              DEFINED ASSET FUNDS
  B.  Names of Depositors:

              MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED
                           SALOMON SMITH BARNEY INC.
                           PAINEWEBBER INCORPORATED
                           DEAN WITTER REYNOLDS INC.

C. Complete address of Depositors' principal executive offices:

 MERRILL LYNCH, PIERCE, FENNER & SMITH               SALOMON SMITH BARNEY INC.
              INCORPORATED                             388 GREENWICH STREET
          DEFINED ASSET FUNDS                               23RD FLOOR
             P.O. BOX 9051                             NEW YORK, N.Y. 10013
       PRINCETON, N.J. 08543-9051

       DEAN WITTER REYNOLDS INC.                     PAINEWEBBER INCORPORATED
         TWO WORLD TRADE CENTER                     1285 AVENUE OF THE AMERICAS
               59TH FLOOR                              NEW YORK, N.Y. 10019
          NEW YORK, N.Y. 10048

D. Names and complete addresses of Agents for service:

       TERESA KONCICK, ESQ.                             DOUGLAS LOWE, ESQ.
          P.O. BOX 9051                              DEAN WITTER REYNOLDS INC.
    PRINCETON, N.J. 08543-9051                        TWO WORLD TRADE CENTER
                                                            59TH FLOOR
                                                       NEW YORK, N.Y. 10048

         MICHAEL KOCHMANN                                ROBERT E. HOLLEY
       388 GREENWICH STREET                         1285 AVENUE OF THE AMERICAS
       NEW YORK, N.Y. 10013                            NEW YORK, N.Y. 10019

                            -----------------------

                                  Copies to:
                         PIERRE DE SAINT PHALLE, ESQ.
                             DAVIS POLK & WARDWELL
                             450 LEXINGTON AVENUE
                           NEW YORK, NEW YORK 10017

                            -----------------------

E: Title of Securities being registered:

       AN INDEFINITE NUMBER OF UNITS OF BENEFICIAL INTEREST PURSUANT TO
              RULE 24F-2 PROMULGATED UNDER THE INVESTMENT COMPANY
                           ACT OF 1940, AS AMENDED.

F: Approximate date of proposed sale to the public:

           AS SOON AS PRACTICABLE AFTER THE ACQUISITION AND DEPOSIT
                        OF THE UNDERLYING OBLIGATIONS.

                            -----------------------

THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR DATES
AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL FILE
A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION STATEMENT
SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(A) OF THE
SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME
EFFECTIVE ON SUCH DATE AS THE COMMISSION, ACTING PURSUANT TO SAID SECTION 8(A),
MAY DETERMINE.
===============================================================================
<PAGE>


                                     PART II
                ADDITIONAL INFORMATION NOT REQUIRED IN PROSPECTUS

     A. The following information relating to the Depositors is incorporated by
reference to the SEC filings indicated and made a part of this Registration
Statement.

I.   Bonding arrangements of each of the Depositors are incorporated by
     reference to Item A of Part II to the Registration Statement on Form S-6
     under the Securities Act of 1933 for Municipal Investment Trust Fund,
     Monthly Payment Series--573 Defined Asset Funds (Reg. No. 333-08241).

II.  The date of organization of each of the Depositors is set forth in Item B
     of Part II to the Registration Statement on Form S-6 under the Securities
     Act of 1933 for Municipal Investment Trust Fund, Monthly Payment
     Series--573 Defined Asset Funds (Reg. No. 333-08241) and is herein
     incorporated by reference thereto.

III. The Charter and By-Laws of each of the Depositors are incorporated herein
     by reference to Exhibits 1.3 through 1.12 to the Registration Statement on
     Form S-6 under the Securities Act of 1933 for Municipal Investment Trust
     Fund, Monthly Payment Series--573 Defined Asset Funds (Reg. No. 333-08241).

IV.  Information as to Officers and Directors of the Depositors has been filed
     pursuant to Schedules A and D of Form BD under Rules 15b1-1 and 15b3-1 of
     the Securities Exchange Act of 1934 and is incorporated by reference to the
     SEC filings indicated and made a part of this Registration Statement:

                                                                 SEC FILE OR
                                                             IDENTIFICATION NO.
                                                             ------------------

Merrill Lynch, Pierce, Fenner & Smith Incorporated................ 8-7221
Salomon Smith Barney Inc.......................................... 8-8177
PaineWebber Incorporated.......................................... 8-16267
Dean Witter Reynolds Inc.......................................... 8-14172

     B. The Internal Revenue Service Employer Identification Numbers of the
Sponsors and Trustee are as follows:

Merrill Lynch, Pierce, Fenner & Smith Incorporated................13-5674085
Salomon Smith Barney Inc..........................................13-1912900
PaineWebber Incorporated..........................................13-2638166
Dean Witter Reynolds Inc..........................................94-0899825
The Chase Manhattan Bank, Trustee.................................13-4994650


                                   UNDERTAKING

     The Sponsors undertake that they will not instruct the Trustee to accept
from (i) Asset Guaranty Reinsurance Company, Municipal Bond Investors Assurance
Corporation or any other insurance company affiliated with any of the Sponsors,
in settlement of any claim, less than an amount sufficient to pay any principal
or interest (and, in the case of a taxability redemption, premium) then due on
any Security in accordance with the municipal bond guaranty insurance policy
attached to such Security or (ii) any affiliate of the Sponsors who has any
obligation with respect to any Security, less than the full amount due pursuant
to the obligation unless such instructions have been approved by the Securities
and Exchange Commission pursuant to Rule 17d-1 under the Investment Company Act
of 1940.

                   SERIES OF MUNICIPAL INVESTMENT TRUST FUND
       DESIGNATED PURSUANT TO RULE 487 UNDER THE SECURITIES ACT OF 1933

                                                                        SEC
Series Number                                                       File Number
-------------                                                       -----------
Multistate Series 401..............................................  333-57375


                       CONTENTS OF REGISTRATION STATEMENT

     THE REGISTRATION STATEMENT ON FORM S-6 COMPRISES THE FOLLOWING PAPERS AND
DOCUMENTS:

     The facing sheet of Form S-6.

     The Cross-Reference Sheet (incorporated by reference to the
Cross-Reference Sheet to the Registration Statement of Defined Asset Funds
Municipal Series, 1933 Act File No. 33-54565).

     The Prospectus.

     Additional Information not included in the Prospectus (Part II).

     The following exhibits:


      1.1  -- Form of Trust Indenture (incorporated by reference to Exhibit
              1.1 to the Registration Statement of Defined Asset Funds,
              Municipal Defined Fund Series 2, 1933 Act File No. 333-61285).
    1.1.1  -- Form of Standard Terms and Conditions of Trust Effective
              October 21, 1993 (incorporated by reference to Exhibit 1.1.1 to
              the Registration Statement of Municipal Investment Trust Fund,
              Multistate Series-48, Defined Asset Funds, 1933 Act File No.
              33-50247).
      1.2  -- Form of Master Agreement Among Underwriters (incorporated by
              reference to Exhibit 1.2 to the Registration Statement of The
              Corporate Income Fund, One Hundred Ninety-Fourth Monthly Payment
              Series, 1933 Act File No. 2-90925).
      2.1 --  Form of Certificate of Beneficial Interest (included in Exhibit
              1.1.1).
     *3.1 --  Opinion of counsel as to the legality of the securities being
              issued including their consent to the use of their name under the
              headings "How the Fund Works --Legal Opinion" in the Prospectus.
     *4.1 --  Consent of the Evaluator.
     *5.1 --  Consent of independent accountants.
      9.1 --  Information Supplement (incorporated by reference to Exhibit 9.1
              to Amendment No. 1 to the Registration Statement of Municipal
              Investment Trust Fund, Multistate Series-409, 1933 Act File
              333-81777).

-------------------
*To be filed with Amendment to Registration Statement.


                              DEFINED ASSET FUNDS
                        MUNICIPAL INVESTMENT TRUST FUND
                               MULTISTATE SERIES

                                   SIGNATURES

     The registrant hereby identifies the series number of Defined Asset Funds
listed on page R-1 for the purposes of the representations required by Rule 487
and represents the following:

     1)   That the portfolio securities deposited in the series as to which
          this registration statement is being filed do not differ materially
          in type or quality from those deposited in such previous series;

     2)   That, except to the extent necessary to identify the specific
          portfolio securities deposited in, and to provide essential
          information for, the series with respect to which this registration
          statement is being filed, this registration statement does not contain
          disclosures that differ in any material respect from those contained
          in the registration statements for such previous series as to which
          the effective date was determined by the Commission or the staff; and

     3)   That it has complied with Rule 460 under the Securities Act of 1933.

     PURSUANT TO THE REQUIREMENTS OF THE SECURITIES ACT OF 1933, THE REGISTRANT
HAS DULY CAUSED THIS REGISTRATION STATEMENT OR AMENDMENT TO THE REGISTRATION
STATEMENT TO BE SIGNED ON ITS BEHALF BY THE UNDERSIGNED THEREUNTO DULY
AUTHORIZED IN THE CITY OF NEW YORK AND STATE OF NEW YORK ON THE 31ST DAY OF
MAY, 2000.

     Signatures appear on pages R-3, R-4, R-5 and R6.

     A majority of the members of the Board of Directors of Merrill Lynch,
Pierce, Fenner & Smith Incorporated has signed this Registration Statement or
Amendment to the Registration Statement pursuant to Powers of Attorney
authorizing the person signing this Registration Statement or Amendment to the
Registration Statement to do so on behalf of such members.

     A majority of the members of the Board of Directors of Salomon Smith Barney
Inc. has signed this Registration Statement or Amendment to the Registration
Statement pursuant to Powers of Attorney authorizing the person signing this
Registration Statement or Amendment to the Registration Statement to do so on
behalf of such members.

     A majority of the members of the Executive Committee of the Board of
Directors of PaineWebber Incorporated has signed this Registration Statement or
Amendment to the Registration Statement pursuant to Powers of Attorney
authorizing the person signing this Registration Statement or Amendment to the
Registration Statement to do so on behalf of such members.

     A majority of the members of the Board of Directors of Dean Witter Reynolds
Inc. has signed this Registration Statement or Amendment to the Registration
Statement pursuant to Powers of Attorney authorizing the person signing this
Registration Statement or Amendment to the Registration Statement to do so on
behalf of such members.


MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED
   DEPOSITOR


By the following persons, who constitute a         Powers of Attorney have been
   majority of the Board of Directors of Merrill   filed under Form SE and  the
   Lynch, Pierce, Fenner & Smith                   following 1933 Act  File
   Incorporated:                                   Numbers: 333-70593

      GEORGE A. SCHIEREN
      JAY M. FIFE



By    J. DAVID MEGLEN
      (As authorized signatory for Merrill Lynch, Pierce, Fenner & Smith
      Incorporated and Attorney-in-fact for the persons listed above)



SALOMON SMITH BARNEY INC.
   DEPOSITOR


By the following persons, who constitute a  Powers of Attorney have been
   majority of the Board of Directors of    filed under the 1933 Act
   Salomon Smith Barney Inc.:               File Numbers:  333-63417 and
                                            333-63033.
      MICHAEL A. CARPENTER
      DERYCK C. MAUGHAN



By    GINA LEMON
      (As authorized signatory for Salomon
      Smith Barney Inc. and Attorney-in-fact
      for the persons listed above)



PAINEWEBBER INCORPORATED
   DEPOSITOR


By the following persons, who constitute         Powers of Attorney have been
   the Board of Directors of PaineWebber         filed under Form SE and the
   Incorporated:                                 following 1933 Act File
                                                 Number: 2-61279

     MARGO N. ALEXANDER
     TERRY L. ATKINSON
     BRIAN M. BAREFOOT
     STEVEN P. BAUM
     MICHAEL CULP
     REGINA A. DOLAN
     JOSEPH J. GRANO, JR.
     EDWARD M. KERSCHNER
     JAMESP. MacGILVRAY
     DONALD B. MARRON
     ROBERT H. SILVER
     MARK B. SUTTON



By    ROBERT E. HOLLEY
      (As authorized signatory for
      PaineWebber Incorporated and
      Attorney-in-fact for the persons listed
      above)



DEAN WITTER REYNOLDS INC.
   DEPOSITOR


By the following persons, who constitute a    Powers of Attorney have been filed
majority of the Board of Directors of Dean    under Form SE and the following
Witter Reynolds Inc.:                         1933 Act File Number: 33-17085
                                              333-13039, 333-47553 and 333-89009

      BRUCE F. ALONSO
      RICHARD M. DeMARTINI
      RAYMOND J. DROP
      JAMES F. HIGGINS
      JOHN J. MACK
      MITCHELL M. MERIN
      STEPHEN R. MILLER
      PHILIP J. PURCELL
      JOHN H. SCHAEFER
      THOMAS C. SCHNEIDER
      ALAN A. SCHRODER
      ROBERT G. SCOTT


By    MICHAEL D. BROWNE
      (As authorized signatory for Dean Witter
      Reynolds Inc. and Attorney-in-fact for the
      persons listed above)




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