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<PAGE> 1 EXHIBIT 23.1 CONSENT OF INDEPENDENT AUDITORS We hereby consent to the incorporation by reference in the Registration Statement on Form S-8 of Prosperity Bancshares, Inc. of our report dated July 12, 2000 on our audit of the financial statements of the Prosperity Bancshares, Inc. 401(k) Profit Sharing Plan Ownership Plan as of December 31, 1999, which report is included in this Annual Report on Form 11-K. John S. Luby, CPA /s/ John S. Luby, CPA Corpus Christi, Texas July 13, 2000
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