INVITROGEN CORP
8-K/A, 1999-09-14
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                   FORM 8-K/A

                                 CURRENT REPORT

     Pursuant To Section 13 or 15(d) of The Securities Exchange Act Of 1934

Date of Report (Date of earliest event reported)    September 14, 1999


                              INVITROGEN CORPORATION
               --------------------------------------------------
               (Exact name of registrant as specified in charter)


         DELAWARE                        0-25317               33-0373077
- ----------------------------    ------------------------     -------------
(State or other jurisdiction    (Commission File Number)     (IRS Employer
   of incorporation)                                       Identification No.)

                     1600 FARADAY AVENUE, CARLSBAD, CA    92008
               ---------------------------------------------------
               (Address of principal executive offices) (Zip Code)


Registrant's telephone number, including area code  (760) 603-7200


                                  NOT APPLICABLE
          -------------------------------------------------------------
          (Former name or former address, if changed since last report)


<PAGE>



ITEM 2.  Acquisition Or Disposition Of Assets

         On August 17, 1999, Invitrogen Corporation ("Invitrogen") completed a
merger pursuant to which NOVEX, a California corporation ("NOVEX"), became a
wholly owned subsidiary of Invitrogen. NOVEX is involved in producing and
supplying protein and nucleic acid electrophoresis, detection and analysis
products used in molecular biology. Upon completion of the merger, each share of
NOVEX stock was converted into the right to receive a fraction of a share of
Invitrogen common stock equal to an exchange ratio of .23188 and each
outstanding option to purchase NOVEX common stock was converted into the right
to purchase a fraction of a share of Invitrogen common stock equal to the same
exchange ratio. The exchange ratio was calculated by dividing 3,000,000 by the
sum of (i) the total number of shares of NOVEX common stock outstanding
immediately prior to the effective time of the merger and (ii) the number of
shares of NOVEX common stock issuable upon exercise of all NOVEX stock options
outstanding on the day immediately preceding the effective time of the merger.
The exchange ratio was based on (i) the negotiated value of NOVEX, (ii) the
number of NOVEX shares and options outstanding, and (iii) the recent market
price of Invitrogen Common Stock. Invitrogen intends to continue NOVEX's
operations as part of Invitrogen's business segment. A total of 3,000,000 shares
of Invitrogen Common Stock are issuable to the shareholders and optionholders of
NOVEX as a result of the exchange of securities in the merger.

ITEM 7.  Financial Statements and Exhibits

         (a)               Financial Statements of NOVEX. The audited financial
                           statements required to be filed are incorporated by
                           reference to Invitrogen Corporation's Registration
                           Statement on Form S-4 (Commission File No.
                           333-82593).

                           The unaudited interim financial statements required
                           to be filed are filed as an exhibit hereto and are
                           incorporated herein by reference.

         (b)               Pro forma financial information. The pro forma
                           financial statements required to be filed are filed
                           as an exhibit hereto and are incorporated herein by
                           reference.

         (c)               Exhibits.

     EXHIBIT                              DESCRIPTION
     -------                              -----------
     2.1                                  Agreement and Plan of Reorganization
                                          dated as of June 14, 1999 by and among
                                          Invitrogen Corporation, Invo Merger
                                          Corporation, and NOVEX. Schedules and
                                          similar attachments to this Exhibit
                                          have not been filed; upon request,
                                          Invitrogen will furnish supplementally
                                          to the Commission a copy of any
                                          omitted schedule. Incorporated by
                                          reference from Annex A to the
                                          Registration Statement on Form S-4
                                          (Commission File No. 333-82593).

     23.1                                 Consent of Ernst & Young LLP,
                                          Independent Auditors.

     27.01                                Financial Data Schedule

     99.1                                 NOVEX audited (i) Consolidated Balance
                                          Sheets as of March 31, 1999 and 1998;
                                          (ii) Consolidated Statements of Income
                                          for the years ended March 31, 1999,
                                          1998 and 1997; (iii) Consolidated
                                          Statements of Stockholders' Equity for
                                          the years ended March 31, 1999, 1998
                                          and 1997; (iv) Consolidated Statements
                                          of Cash Flows for the years ended
                                          March 31, 1999, 1998 and 1997; and
                                          related Notes to Consolidated
                                          Financial Statements. Incorporated by
                                          reference to Invitrogen Corporation's
                                          Registration Statement on Form S-4
                                          (Commission File No. 333-82593).

                                        1
<PAGE>

     99.2                                 NOVEX unaudited (i) Consolidated
                                          Balance Sheet as of June 30, 1999;
                                          (ii) Consolidated Statements of
                                          Income for the three months ended
                                          June 30, 1999 and 1998; and (iii)
                                          Consolidated Statements of Cash Flows
                                          for the three months ended June 30,
                                          1999 and 1998.

     99.3                                 Invitrogen Corporation and NOVEX
                                          Unaudited Pro Forma (i) Combined
                                          Balance Sheet as of June 30, 1999;
                                          (ii) Combined Statements of Income for
                                          the six months ended June 30, 1999 and
                                          1998 and for the years ended December
                                          31, 1998, 1997 and 1996; and (iii)
                                          related Notes to Combined Financial
                                          Statements.



                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.



Date:    September 14, 1999                     INVITROGEN CORPORATION


                                                By:  /s/ James R. Glynn
                                                     -----------------------
                                                     James R. Glynn
                                                     Chief Financial Officer



                                        2
<PAGE>



                                INDEX OF EXHIBITS

     EXHIBIT                              DESCRIPTION
     -------                              -----------
     2.1                                  Agreement and Plan of Reorganization
                                          dated as of June 14, 1999 by and among
                                          Invitrogen Corporation, Invo Merger
                                          Corporation, and NOVEX. Schedules and
                                          similar attachments to this Exhibit
                                          have not been filed; upon request,
                                          Invitrogen will furnish supplementally
                                          to the Commission a copy of any
                                          omitted schedule. Incorporated by
                                          reference from Annex A to the
                                          Registration Statement on Form S-4
                                          (Commission File No. 333-82593).

     23.1                                 Consent of Ernst & Young LLP,
                                          Independent Auditors.

     27.01                                Financial Data Schedule

     99.1                                 NOVEX audited (i) Consolidated Balance
                                          Sheets as of March 31, 1999 and 1998;
                                          (ii) Consolidated Statements of Income
                                          for the years ended March 31, 1999,
                                          1998 and 1997; (iii) Consolidated
                                          Statements of Stockholders' Equity for
                                          the years ended March 31, 1999, 1998
                                          and 1997; (iv) Consolidated Statements
                                          of Cash Flows for the years ended
                                          March 31, 1999, 1998 and 1997; and
                                          related Notes to Consolidated
                                          Financial Statements. Incorporated by
                                          reference to Invitrogen Corporation's
                                          Registration Statement on Form S-4
                                          (Commission File No.
                                          333-82593).

     99.2                                 NOVEX unaudited (i) Consolidated
                                          Balance Sheet as of June 30, 1999;
                                          (ii) Consolidated Statements of
                                          Income for the three months ended
                                          June 30, 1999 and 1998; and (iii)
                                          Consolidated Statements of Cash Flows
                                          for the three months ended June 30,
                                          1999 and 1998.

     99.3                                 Invitrogen Corporation and NOVEX
                                          Unaudited Pro Forma (i) Combined
                                          Balance Sheet as of June 30, 1999;
                                          (ii) Combined Statements of Income for
                                          the six months ended June 30, 1999 and
                                          1998 and for the years ended December
                                          31, 1998, 1997 and 1996; and (iii)
                                          related Notes to Combined Financial
                                          Statements.


                                        3

<PAGE>

                                  EXHIBIT 23.1

               CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS

      We consent to the incorporation by reference in the Form 8-K/A to be
filed on September 14, 1999 of Invitrogen Corporation of our report dated May
28, 1999, except for the third paragraph of Note 11, as to which the date is
August 17, 1999, with respect to the consolidated financial statements of
Novex, included in the Registration Statement (Form S-4, No. 333-82593) and
Prospectus of Invitrogen Corporation to be filed with the Securities and
Exchange Commission.


                                          ERNST & YOUNG LLP


San Diego, California
September 13, 1999


<PAGE>
                                  EXHIBIT 99.2

                                      NOVEX
                  INTERIM CONDENSED CONSOLIDATED BALANCE SHEET
                                 (IN THOUSANDS)

<TABLE>
<CAPTION>
                                                                   JUNE 30, 1999
                                                                   -------------
                                                                    (UNAUDITED)
<S>                                                                  <C>
ASSETS
Current Assets:
    Cash and cash equivalents ...................................    $    111
    Accounts and notes receivable ...............................       3,481
    Inventories .................................................       2,845
    Deferred income taxes .......................................         201
    Prepaid expenses and other current assets ...................         167
                                                                     --------
        Total current assets ....................................       6,805
Property and equipment, net .....................................       2,643
Intangible assets, net ..........................................         436
Other assets ....................................................         186
                                                                     --------
Total Assets ....................................................    $ 10,070
                                                                     --------
                                                                     --------

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
    Note payable to bank ........................................    $    570
    Current portion of long-term debt............................       1,031
    Accounts payable ............................................       1,334
    Accrued expenses ............................................       1,076
    Income taxes payable ........................................         355
                                                                     --------
        Total current liabilities ...............................       4,366
                                                                     --------
Long-term debt, less current maturities .........................         825
Redeemable convertible preferred stock ..........................       2,939
Stockholders' Equity:
    Common stock, par value......................................         750
    Other stockholders' equity...................................       1,190
                                                                     --------
Total stockholders' equity ......................................       1,940
                                                                     --------
Total Liabilities and Stockholders' Equity ......................    $ 10,070
                                                                     --------
                                                                     --------
</TABLE>


                                        1
<PAGE>

                                      NOVEX
                    INTERIM CONSOLIDATED STATEMENTS OF INCOME
                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                                    THREE MONTHS ENDED
                                                                         JUNE 30,
                                                                    ------------------
                                                                    1999          1998
                                                                    ----          ----
                                                                       (UNAUDITED)
<S>                                                               <C>            <C>
Revenues........................................................  $  6,936       $  5,081
Cost of Revenues................................................     3,178          2,284
                                                                  --------       --------
   Gross margin.................................................     3,758          2,797
Operating Expenses:
  Sales and marketing...........................................     1,616          1,151
  General and administrative....................................     1,053            904
  Research and development......................................       486            412
                                                                  --------       --------
     Total operating expenses...................................     3,155          2,467
                                                                  --------       --------
       Income from operations...................................       603            330
                                                                  --------       --------
Other Income (Expense):
  Gain (loss) on foreign currency transactions..................         4             (5)
  Interest and other expense....................................       (50)           (43)
                                                                  --------       --------
                                                                       (46)           (48)
                                                                  --------       --------
Income before provision for income taxes........................       557            282
Provision for income taxes......................................       212            106
                                                                  --------       --------
Net income......................................................       345            176
   Less:  Preferred stock dividends.............................       (39)           (39)
                                                                  --------       --------
       Income available to common stockholders..................  $    306       $    137
                                                                  --------       --------
                                                                  --------       --------
Earnings per share:
  Basic                                                           $   0.05       $   0.02
                                                                  --------       --------
                                                                  --------       --------
  Diluted.......................................................  $   0.03       $   0.02
                                                                  --------       --------
                                                                  --------       --------
Weighted average shares used in per share calculation:
  Basic                                                              6,710          6,687
  Diluted.......................................................    12,205         10,985

</TABLE>

                                        2
<PAGE>

                                      NOVEX
                  INTERIM CONSOLIDATED STATEMENTS OF CASH FLOWS
                                 (IN THOUSANDS)

<TABLE>
<CAPTION>
                                                                                      THREE MONTHS ENDED
                                                                                           JUNE 30,
                                                                                      ------------------
                                                                                      1999           1998
                                                                                      ----           ----
                                                                                         (UNAUDITED)
<S>                                                                                 <C>            <C>
CASH FLOWS FROM OPERATING ACTIVITIES:
Net Income....................................................................      $    345       $    176
Adjustments to reconcile net income to net cash provided by
  operating activities:
Depreciation and amortization.................................................           213            161
Deferred income taxes.........................................................             -             19
Provision for uncollectible accounts..........................................             -              5
Changes in operating assets and liabilities:
  Accounts receivable.........................................................          (142)          (413)
  Inventories.................................................................          (280)          (737)
  Prepaid expenses and other current assets...................................           (62)           (74)
  Account payable.............................................................            (7)           132
  Accrued expenses............................................................          (127)           172
  Income taxes payable........................................................           170              1
                                                                                    --------       --------
     Net cash provided (used) by operating activities.........................           110           (558)
                                                                                    --------       --------
CASH FLOWS FROM INVESTING ACTIVITIES:
  Purchases of property and equipment ........................................          (256)          (338)
  Payments for intangible assets..............................................            (2)            (2)
  Other assets................................................................           (56)             -
                                                                                    --------       --------
     Net cash used by investing activities....................................          (314)          (340)
                                                                                    --------       --------
CASH FLOWS FROM FINANCING ACTIVITIES:
Borrowings on notes payable to bank, net......................................            19             50
Additions to long-term debt...................................................             -            921
Payments on long-term debt....................................................             -            (22)
Proceeds from sale of common stock............................................            12              -
                                                                                    --------       --------
     Net cash provided by financing activities................................            31            949
                                                                                    --------       --------
Effect of exchange rate changes on cash.......................................           (22)            (1)
                                                                                    --------       --------
     Net increase (decrease) in cash and cash equivalents.....................          (195)            50
Cash and cash equivalents, beginning of period................................           306            188
                                                                                    --------       --------
Cash and cash equivalents, end of period......................................      $    111       $    238
                                                                                    --------       --------
                                                                                    --------       --------
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid for interest........................................................      $     35       $     48
                                                                                    --------       --------
                                                                                    --------       --------
Cash paid for income taxes....................................................      $     60       $     91
                                                                                    --------       --------
                                                                                    --------       --------
NONCASH INVESTING AND FINANCING ACTIVITIES:
  Assets acquired with long-term debt.........................................      $      -       $    500
                                                                                    --------       --------
                                                                                    --------       --------
</TABLE>

                                        3

<PAGE>

                                  EXHIBIT 99.3

          INVITROGEN UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS

         The following unaudited pro forma condensed combined balance sheet as
of June 30, 1999, illustrates the effect of the merger as if it had occurred on
June 30, 1999. The following unaudited pro forma combined statements of income
for the six months ended June 30, 1999 and 1998 and for the three years ended
December 31, 1998, illustrate the effect of the merger as if it had occurred on
January 1, 1996. There were no material differences between the accounting
policies of Invitrogen and NOVEX and, therefore, no adjustments have been made
to the pro forma financial statements. The unaudited pro forma combined
statements of income for the three years ended December 31, 1998 include both
Invitrogen's and NOVEX's financial data for these same periods, whereas in our
previously filed registration statement for the merger NOVEX's financial data
for the three fiscal years ended March 31, 1999 was used in the unaudited pro
forma combined statements of income.

         The pro forma combined financial statements are presented for
comparative purposes only and are not necessarily indicative of the combined
financial position or results of operations of future periods or the results
that actually would have been realized had Invitrogen and NOVEX been a single
entity during the periods presented.

         Pursuant to the terms of the merger, each share of NOVEX stock was
converted into the right to receive .23188 of a share of Invitrogen. The pro
forma combined financial statements have been derived from the respective
historical audited and unaudited consolidated financial statements of
Invitrogen and NOVEX and should be read in conjunction with such financial
statements and the notes thereto that are incorporated herein by reference.

                                        1

<PAGE>

                       INVITROGEN CORPORATION AND NOVEX
                 UNAUDITED PRO FORMA COMBINED BALANCE SHEET
                                 JUNE 30, 1999
                                 (IN THOUSANDS)

<TABLE>
<CAPTION>
                                                              HISTORICAL       HISTORICAL         PRO FORMA           PRO FORMA
                                                              INVITROGEN          NOVEX          ADJUSTMENTS          COMBINED
                                                              ----------       ----------        -----------          ---------
<S>                                                          <C>               <C>               <C>                 <C>
ASSETS
Current Assets:
    Cash and cash equivalents .......................        $    36,094       $       111       $         -         $    36,205
    Short-term investments ..........................              2,439                 -                 -               2,439
    Accounts and notes receivable ...................              4,116             3,481                (3) (2)          7,594
    Inventories .....................................              2,823             2,845                 -               5,668
    Deferred income taxes ...........................                595               201                 -                 796
    Prepaid expenses and other current assets .......              1,539               167               692  (4)          2,398
                                                             -----------       -----------       -----------         -----------
        Total current assets ........................             47,606             6,805               689              55,100
Property and equipment, net .........................              7,182             2,643                 -               9,825
Intangible assets, net ..............................              3,192               436                 -               3,628
Other assets ........................................                171               186                 -                 357
                                                             -----------       -----------       -----------         -----------
Total Assets ........................................        $    58,151       $    10,070       $       689         $    68,910
                                                             -----------       -----------       -----------         -----------
                                                             -----------       -----------       -----------         -----------

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
    Note payable to bank ............................        $         -       $       570       $         -         $       570
    Current portion of long-term obligations ........                438             1,031                 -               1,469
    Accounts payable ................................              1,742             1,334                (3) (2)          3,073
    Accrued expenses ................................              1,697             1,076             4,442  (4)          7,215
    Income taxes payable ............................                631               355              (663) (4)            323
                                                             -----------       -----------       -----------         -----------
        Total current liabilities ...................              4,508             4,366             3,776              12,650
                                                             -----------       -----------       -----------         -----------

Long-term obligations, less current maturities ......                664               825                 -               1,489
Redeemable convertible preferred stock ..............                  -             2,939            (2,939) (3)              -

Stockholders' Equity:
    Common stock, par value..........................                134               750              (724) (3)            160
    Other stockholders' equity.......................             52,845             1,190               576  (3)(4)      54,611
                                                             -----------       -----------       -----------         -----------

Total stockholders' equity ..........................             52,979             1,940              (148)             54,771
                                                             -----------       -----------       -----------         -----------
Total Liabilities and Stockholders' Equity ..........        $    58,151       $    10,070       $       689         $    68,910
                                                             -----------       -----------       -----------         -----------
                                                             -----------       -----------       -----------         -----------
</TABLE>

       See Notes to Unaudited Pro Forma Combined Financial Statements.


                                        2
<PAGE>

                       INVITROGEN CORPORATION AND NOVEX
              UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME
                        SIX MONTHS ENDED JUNE 30, 1999
                    (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                             HISTORICAL     HISTORICAL       PRO FORMA         PRO FORMA
                                                             INVITROGEN        NOVEX        ADJUSTMENTS         COMBINED
                                                             ----------     ----------      -----------        ---------
<S>                                                          <C>             <C>             <C>                <C>
Revenues.................................................     $ 19,888       $ 13,897        $    (19) (2)      $ 33,766
Cost of Revenues.........................................        5,087          6,496              (5) (2)        11,578
                                                              --------       --------        --------           --------
   Gross margin..........................................       14,801          7,401             (14)            22,188
Operating Expenses:
  Sales and marketing....................................        3,878          3,128               -              7,006
  General and administrative.............................        2,498          1,900               -              4,398
  Research and development...............................        3,963            961             (14) (2)         4,910
                                                              --------       --------        --------           --------
     Total operating expenses............................       10,339          5,989             (14)            16,314
                                                              --------       --------        --------           --------
       Income from operations............................        4,462          1,412               -              5,874
                                                              --------       --------        --------           --------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........         (206)             -               -               (206)
  Interest and other expense.............................          (13)          (126)              -               (139)
  Interest and other income..............................          602              1               -                603
                                                              --------       --------        --------           --------
                                                                   383           (125)              -                258
                                                              --------       --------        --------           --------
Income before provision for income taxes.................        4,845          1,287               -              6,132
Provision for income taxes...............................        1,696            488               -              2,184
                                                              --------       --------        --------           --------
Net income...............................................        3,149            799               -              3,948
Less:  Preferred stock dividends.........................         (163)           (78)             78  (3)          (163)
      Accretion of non-voting redeemable common stock....          (74)             -               -                (74)
      Adjustment to beneficial conversion feature related
        to convertible preferred stock...................          985              -               -                985
                                                              --------       --------        --------           --------
       Income available to common stockholders...........     $  3,897       $    721        $     78           $  4,696
                                                              --------       --------        --------           --------
                                                              --------       --------        --------           --------
Earnings per share:
  Basic..................................................     $   0.32       $   0.11                           $   0.32
                                                              --------       --------                           --------
                                                              --------       --------                           --------
  Diluted................................................     $   0.27       $   0.07                           $   0.27
                                                              --------       --------                           --------
                                                              --------       --------                           --------
Weighted average shares used in per share calculation:
  Basic..................................................       12,116          6,706                             14,645   (3)
  Diluted................................................       14,230         11,810                             17,101   (3)
</TABLE>

      See Notes to Unaudited Pro Forma Combined Financial Statements.

                                        3

<PAGE>

                         INVITROGEN CORPORATION AND NOVEX
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME
                           SIX MONTHS ENDED JUNE 30, 1998
                        (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                             HISTORICAL     HISTORICAL       PRO FORMA         PRO FORMA
                                                             INVITROGEN        NOVEX        ADJUSTMENTS         COMBINED
                                                             ----------     ----------      -----------        ---------
<S>                                                          <C>             <C>             <C>                <C>
Revenues.................................................     $ 14,873       $  9,857        $    (25) (2)      $ 24,705
Cost of Revenues.........................................        4,065          4,221              (6) (2)         8,280
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       10,808          5,636             (19)            16,425
Operating Expenses:
  Sales and marketing....................................        3,438          1,873               -              5,311
  General and administrative.............................        2,098          1,811               -              3,909
  Research and development...............................        3,306            762             (19) (2)         4,049
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................        8,842          4,446             (19)            13,269
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        1,966          1,190               -              3,156
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........            3             (9)              -                 (6)
  Interest and other expense.............................          (18)          (116)              -               (134)
  Interest and other income..............................          184              3               -                187
                                                             ---------      ---------       ---------          ---------
                                                                   169           (122)              -                 47
                                                             ---------      ----------      ---------          ---------
Income before provision for income taxes.................        2,135          1,068               -              3,203
Provision for income taxes...............................          761            410               -              1,171
                                                              --------       --------        --------           ---------
Net income...............................................        1,374            658               -              2,032
Less:  Preferred stock dividends.........................         (450)           (77)             77  (3)          (450)
      Accretion of non-voting redeemable common stock....          (98)             -               -                (98)
                                                             ---------      ---------       ---------          ---------
       Income available to common stockholders...........     $    826       $    581        $     77           $  1,484
                                                             ---------      ---------       ---------          ---------
                                                             ---------      ---------       ---------          ---------
Earnings per share:
  Basic..................................................     $   0.09       $   0.09                           $   0.12
                                                             ---------      ---------                          ---------
                                                             ---------      ---------                          ---------
  Diluted................................................     $   0.08       $   0.05                           $   0.11
                                                             ---------      ---------                          ---------
                                                             ---------      ---------                          ---------
Weighted average shares used in per share calculation:
  Basic..................................................        9,632          6,687                             12,157   (3)
  Diluted................................................       10,996         10,985                             13,581   (3)
</TABLE>

      See Notes to Unaudited Pro Forma Combined Financial Statements.

                                       4
<PAGE>

                         INVITROGEN CORPORATION AND NOVEX
                 UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME
                           YEAR ENDED DECEMBER 31, 1998
                       (IN THOUSANDS, EXCEPT PER SHARE DATA)
<TABLE>
<CAPTION>
                                                             HISTORICAL     HISTORICAL       PRO FORMA         PRO FORMA
                                                             INVITROGEN        NOVEX        ADJUSTMENTS         COMBINED
                                                             ----------     ----------      -----------        ---------
<S>                                                          <C>             <C>             <C>                <C>
Revenues.................................................     $ 31,414       $ 22,293        $    (47) (2)      $ 53,660
Cost of Revenues.........................................        8,642         10,560             (11) (2)        19,191
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       22,772         11,733             (36)            34,469
Operating Expenses:
  Sales and marketing....................................        6,976          4,376               -             11,352
  General and administrative.............................        4,428          3,663               -              8,091
  Research and development...............................        7,209          1,430             (36) (2)         8,603
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................       18,613          9,469             (36)            28,046
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        4,159          2,264               -              6,423
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........           61            (36)              -                 25
  Interest and other expense.............................          (35)          (214)              -               (249)
  Interest and other income..............................          431             10               -                441
                                                             ---------      ---------       ---------          ---------
                                                                   457           (240)              -                217
                                                             ---------      ----------      ---------          ---------
Income before provision for income taxes.................        4,616          2,024               -              6,640
Provision for income taxes...............................        1,638            772               -              2,410
                                                              ---------      --------        --------           ---------
Net income...............................................        2,978          1,252               -              4,230
Less:  Preferred stock dividends.........................         (900)          (155)            155  (3)          (900)
      Accretion of non-voting redeemable common stock....         (204)             -               -               (204)
                                                             ---------      ---------       ---------          ---------
       Income available to common stockholders...........     $  1,874       $  1,097        $    155           $  3,126
                                                             ---------      ---------       ---------          ---------
                                                             ---------      ---------       ---------          ---------
Earnings per share:
  Basic .................................................     $   0.19       $   0.16                           $   0.26
                                                             ---------      ---------                          ---------
                                                             ---------      ---------                          ---------
  Diluted................................................     $   0.17       $   0.11                           $   0.23
                                                             ---------      ---------                          ---------
                                                             ---------      ---------                          ---------
Weighted average shares used in per share calculation:
  Basic..................................................        9,626          6,691                             12,152   (3)
  Diluted................................................       11,208         11,195                             13,883   (3)
</TABLE>

        See Notes to Unaudited Pro Forma Combined Financial Statements.

                                       5
<PAGE>

                        INVITROGEN CORPORATION AND NOVEX
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME
                          YEAR ENDED DECEMBER 31, 1997
                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                             HISTORICAL     HISTORICAL       PRO FORMA         PRO FORMA
                                                             INVITROGEN        NOVEX        ADJUSTMENTS         COMBINED
                                                             ----------     ----------      -----------        ---------
<S>                                                          <C>             <C>             <C>                <C>
Revenues.................................................     $ 24,965       $ 16,240        $    (23) (2)      $ 41,182
Cost of Revenues.........................................        7,989          7,976              (7) (2)        15,958
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       16,976          8,264             (16)            25,224
Operating Expenses:
  Sales and marketing....................................        4,959          3,346               -              8,305
  General and administrative.............................        3,932          3,380               -              7,312
  Research and development...............................        4,416          1,518             (16) (2)         5,918
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................       13,307          8,244             (16)            21,535
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        3,669             20               -              3,689
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........          145              -               -                145
  Interest and other expense.............................          (88)          (154)              -               (242)
  Interest and other income..............................          211              3               -                214
                                                             ---------      ---------       ---------          ---------
                                                                   268           (151)              -                117
                                                             ---------      ----------      ---------          ---------
Income before provision for income taxes.................        3,937           (131)              -              3,806
Provision for income taxes...............................        1,413            (42)              -              1,371
                                                             ---------      ----------      ---------          ---------
Net income...............................................        2,524            (89)              -              2,435
Less:  Preferred stock dividends.........................         (475)          (147)            147  (3)          (475)
      Accretion of non-voting redeemable common stock....         (175)             -               -               (175)
      Adjustment to beneficial conversion feature related
        to convertible preferred stock...................      (15,000)             -               -            (15,000)
                                                             ---------      ----------      ---------          ---------
       Income available to common stockholders...........     $(13,126)      $   (236)       $    147           $(13,215)
                                                             ---------      ----------      ---------          ---------
                                                             ---------      ----------      ---------          ---------
Earnings per share:
  Basic..................................................     $  (1.47)      $  (0.04)                          $  (1.15)
                                                             ---------      ----------                         ---------
                                                             ---------      ----------                         ---------
  Diluted................................................     $  (1.47)      $  (0.04)                          $  (1.15)
                                                             ---------      ----------                         ---------
                                                             ---------      ----------                         ---------
Weighted average shares used in per share calculation:
  Basic..................................................        8,939          6,679                             11,461   (3)
  Diluted................................................        8,939          6,679                             11,461   (3)
</TABLE>

      See Notes to Unaudited Pro Forma Combined Financial Statements.

                                       6
<PAGE>

                       INVITROGEN CORPORATION AND NOVEX
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME
                           YEAR ENDED DECEMBER 31, 1996
                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                             HISTORICAL     HISTORICAL       PRO FORMA         PRO FORMA
                                                             INVITROGEN        NOVEX        ADJUSTMENTS         COMBINED
                                                             ----------     ----------      -----------        ---------
<S>                                                          <C>             <C>             <C>                <C>
Revenues.................................................     $ 19,121       $ 13,450        $    (15) (2)      $ 32,556
Cost of Revenues.........................................        5,818          6,280              (4) (2)        12,094
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       13,303          7,170             (11)            20,462
Operating Expenses:
  Sales and marketing....................................        4,236          2,327               -              6,563
  General and administrative.............................        3,880          2,411               -              6,291
  Research and development...............................        2,659          1,234             (11) (2)         3,882
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................       10,775          5,972             (11)            16,736
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        2,528          1,198               -              3,726
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........          172              -               -                172
  Interest and other expense.............................          (87)          (131)              -               (218)
  Interest and other income..............................           70              4               -                 74
                                                             ---------      ---------       ---------          ---------
                                                                   155           (127)              -                 28
                                                             ---------      ----------      ---------          ---------
Income before provision for income taxes.................        2,683          1,071               -              3,754
Provision for income taxes...............................          939            479               -              1,418
                                                             ---------      ----------      ---------          ---------
Net income...............................................        1,744            592               -              2,336
Less: Accretion of non-voting redeemable common stock....         (171)             -               -               (171)
                                                             ---------      ----------      ---------          ---------
       Income available to common stockholders...........     $  1,573       $    592        $      -           $  2,165
                                                             ---------      ----------      ---------          ---------
                                                             ---------      ----------      ---------          ---------
Earnings per share:
  Basic..................................................     $   0.19       $   0.09                           $   0.20
                                                             ---------      ----------                         ---------
                                                             ---------      ----------                         ---------
  Diluted................................................     $   0.16       $   0.06                           $   0.17
                                                             ---------      ----------                         ---------
                                                             ---------      ----------                         ---------
Weighted average shares used in per share calculation:
  Basic..................................................        8,356          6,679                             10,831   (3)
  Diluted................................................       10,080         10,672                             12,554   (3)
</TABLE>

      See Notes to Unaudited Pro Forma Combined Financial Statements.

                                       7
<PAGE>

                        INVITROGEN CORPORATION AND NOVEX
           NOTES TO UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS

1.   BASIS OF PRESENTATION

     The Merger is intended to be accounted for as a pooling of interests.
     Under this method of accounting the unaudited pro forma combined
     statements of income combine the historical statements of income for
     Invitrogen for the six months ended June 30, 1999 and 1998 and three
     years ended December 31, 1998 with the historical statements of income
     for NOVEX for the same periods. All unaudited pro forma combined income
     statements assume consummation of the Merger on January 1, 1996.

     The unaudited pro forma combined balance sheet combines the historical
     balance sheets of Invitrogen and NOVEX at June 30, 1999 and assumes
     consummation of the Merger on June 30, 1999.

2.   INTERCOMPANY TRANSACTIONS

     All significant intercompany sales and balances have been eliminated in
     the combination.

3.   MERGER TRANSACTION

     The unaudited pro forma combined financial statements reflects the
     conversion of NOVEX redeemable convertible preferred stock into NOVEX
     common stock and the subsequent issuance of 2.5 million shares of
     Invitrogen common stock for all of the outstanding common stock for
     NOVEX at an exchange ratio of 0.23188. The unaudited pro forma combined
     net income (loss) per share also reflects the assumption of all
     outstanding NOVEX stock options by Invitrogen at the same exchange
     ratio.

4.   MERGER COSTS

     Costs incurred as a result of the Merger are expected to be $4.4 million
     and are subject to change. These costs will be expensed after the Merger
     is completed. The unaudited pro forma combined statements of income
     exclude expenses related to the Merger as they are nonrecurring in
     nature.

                                       8

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<MULTIPLIER> 1,000

<S>                             <C>                     <C>
<PERIOD-TYPE>                   3-MOS                   3-MOS
<FISCAL-YEAR-END>                          MAR-31-2000             MAR-31-1999
<PERIOD-START>                             APR-01-1999             APR-01-1998
<PERIOD-END>                               JUN-30-1999             JUN-30-1998
<CASH>                                             111                     238
<SECURITIES>                                         0                       0
<RECEIVABLES>                                    3,587                   2,151
<ALLOWANCES>                                       106                     130
<INVENTORY>                                      2,845                   2,253
<CURRENT-ASSETS>                                 6,805                   5,473
<PP&E>                                           4,926                   3,910
<DEPRECIATION>                                   2,283                   1,552
<TOTAL-ASSETS>                                  10,070                   8,317
<CURRENT-LIABILITIES>                            4,366                   4,460
<BONDS>                                              0                       0
                            2,939                   2,784
                                          0                       0
<COMMON>                                           750                     561
<OTHER-SE>                                       1,190                     139
<TOTAL-LIABILITY-AND-EQUITY>                    10,070                   8,317
<SALES>                                          6,936                   5,081
<TOTAL-REVENUES>                                 6,936                   5,081
<CGS>                                            3,178                   2,284
<TOTAL-COSTS>                                    3,178                   2,284
<OTHER-EXPENSES>                                 3,155                   2,467
<LOSS-PROVISION>                                     0                       0
<INTEREST-EXPENSE>                                  50                      43
<INCOME-PRETAX>                                    557                     282
<INCOME-TAX>                                       212                     106
<INCOME-CONTINUING>                                345                     176
<DISCONTINUED>                                       0                       0
<EXTRAORDINARY>                                      0                       0
<CHANGES>                                            0                       0
<NET-INCOME>                                       345                     176
<EPS-BASIC>                                       0.05                    0.02
<EPS-DILUTED>                                     0.03                    0.02


</TABLE>


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