INVITROGEN CORP
8-K/A, 2000-02-17
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                   FORM 8-K/A

                                 CURRENT REPORT

          Pursuant To Section 13 or 15(d) of The Securities Exchange Act Of 1934

Date of Report (Date of earliest event reported)    February 2, 2000

                             INVITROGEN CORPORATION
               --------------------------------------------------
               (Exact name of registrant as specified in charter)

          DELAWARE                     0-25317                 33-0373077
          --------                     -------                 ----------
(State or other jurisdiction    (Commission File Number)      (IRS Employer
of incorporation)                                           Identification No.)


        1600 FARADAY AVENUE, CARLSBAD, CA                            92008
        ------------------------------------------------------------------
   (Address of principal executive offices)                       (Zip Code)

Registrant's telephone number, including area code  (760) 603-7200

                                 NOT APPLICABLE
        ------------------------------------------------------------------
          (Former name or former address, if changed since last report)


<PAGE>


ITEM 2.  Acquisition Or Disposition Of Assets

         On February 2, 2000, Invitrogen Corporation ("Invitrogen") completed
a merger pursuant to which Research Genetics, Inc., an Alabama corporation,
merged with a wholly owned Delaware subsidiary of Invitrogen. Research
Genetics, now a Delaware corporation, is a supplier of products and services
for functional genomics and gene-based drug discovery research. Upon
completion of the merger, each share of Research Genetics stock was converted
into the right to receive 64 shares of Invitrogen common stock. The exchange
ratio was calculated by dividing 3,200,000 by the total number of shares of
Research Genetics common stock outstanding immediately prior to the effective
time of the merger. The exchange ratio was based on (i) the negotiated value
of Research Genetics, (ii) the number of Research Genetics shares
outstanding, and (iii) the market price of Invitrogen Common Stock.
Invitrogen intends to continue Research Genetics' operations as part of
Invitrogen's business. A total of 3,200,000 shares of Invitrogen Common Stock
were issued to the shareholders of Research Genetics as a result of the
exchange of securities in the merger.

         In the merger, Invitrogen also acquired through Research Genetics
four tracts of improved real estate which comprise the facilities used by
Research Genetics.  These facilities include approximately 153,000 square
feet of office, production, research and development space, as well as space
for planned expansion. At this time Invitrogen intends to continue to use
these facilities for their current purposes.

ITEM 5.  Other Events

         On February 17, 2000 Invitrogen Corporation reported earnings
information for its year ending December 31, 1999. The news release is filed as
an exhibit hereto and is incorporated herein by reference.

ITEM 7.  Financial Statements and Exhibits

         a) Financial Statements of Research Genetics. The audited financial
            statements for Research Genetics, Inc. as of December 31, 1999 and
            1998 are filed as an exhibit hereto and are incorporated herein by
            reference.

         b) Pro forma financial information. Pro forma financial statements for
            Invitrogen Corporation and Research Genetics for the years ended
            December 31, 1999, 1998 and 1997 are filed as an exhibit hereto and
            are incorporated herein by reference.

         c) Exhibits.

     Exhibit                Description
     -------                -----------

     2.1                    Agreement and Plan of Reorganization dated as of
                            February 1, 2000 by and among Invitrogen
                            Corporation, RG merger Corporation and Research
                            Genetics, Inc. Incorporated by reference to
                            Invitrogen Corporation's filing on form 8-K dated
                            February 16, 2000.

     23.1                   Consent of Arthur Andersen LLP, Independent Public
                            Accountants

     99.1                   Invitrogen Corporation News Release dated February
                            17, 2000

     99.2                   Research Genetics audited (i) Balance Sheets as of
                            December 31, 1999 and 1998; (ii) Statements of
                            Income for the years ended December 31, 1999 and
                            1998; (iii) Statements of Stockholders' Equity for
                            the years ended December 31, 1999 and 1998; (iv)
                            Statements of Cash Flows for the years ended
                            December 31, 1999 and 1998; and related Notes to
                            Financial Statements.

     99.3                   Research Genetics audited (i) Balance Sheets as of
                            December 31, 1998 and 1997; (ii) Statements of
                            Income for the years ended December 31, 1998 and
                            1997; (iii) Statements of Stockholders' Equity for
                            the years ended December 31, 1998 and 1997; (iv)
                            Statements of Cash Flows for the years ended
                            December 31, 1998 and 1997; and related Notes to
                            Financial Statements. Incorporated by reference to
                            Invitrogen Corporation's filing on Form 8-K dated
                            February 16, 2000.



                                          2
<PAGE>

     99.4                   Invitrogen Corporation and Research Genetics
                            Unaudited Pro Forma (i) Combined Balance Sheet as of
                            December 31, 1999; (ii) Combined Statements of
                            Income for the years ended December 31, 1999, 1998
                            and 1997; and (iii) related Notes to Combined
                            Financial Statements.

     27.01                  Financial Data Schedule - Invitrogen Corporation

     27.02                  Financial Data Schedule - Research Genetics


                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Date:    February 17, 2000                INVITROGEN CORPORATION

                                          By:  /s/ James R. Glynn
                                               --------------------------------
                                          James R. Glynn
                                          Chief Financial Officer



                                       3
<PAGE>


                                                 INDEX OF EXHIBITS

     Exhibit                Description
     -------                -----------

     2.1                    Agreement and Plan of Reorganization dated as of
                            February 1, 2000 by and among Invitrogen
                            Corporation, RG merger Corporation and Research
                            Genetics, Inc. Incorporated by reference to
                            Invitrogen Corporation's filing on form 8-K dated
                            February 16, 2000.

     23.1                   Consent of Arthur Andersen LLP, Independent Public
                            Accountants

     99.1                   Invitrogen Corporation News Release dated February
                            17, 2000

     99.2                   Research Genetics audited (i) Balance Sheets as of
                            December 31, 1999 and 1998; (ii) Statements of
                            Income for the years ended December 31, 1999 and
                            1998; (iii) Statements of Stockholders' Equity for
                            the years ended December 31, 1999 and 1998; (iv)
                            Statements of Cash Flows for the years ended
                            December 31, 1999 and 1998; and related Notes to
                            Financial Statements.

     99.3                   Research Genetics audited (i) Balance Sheets as of
                            December 31, 1998 and 1997; (ii) Statements of
                            Income for the years ended December 31, 1998 and
                            1997; (iii) Statements of Stockholders' Equity for
                            the years ended December 31, 1998 and 1997; (iv)
                            Statements of Cash Flows for the years ended
                            December 31, 1998 and 1997; and related Notes to
                            Financial Statements. Incorporated by reference to
                            Invitrogen Corporation's filing on Form 8-K dated
                            February 16, 2000.

     99.4                   Invitrogen Corporation and Research Genetics
                            Unaudited Pro Forma (i) Combined Balance Sheet as of
                            December 31, 1999; (ii) Combined Statements of
                            Income for the years ended December 31, 1999, 1998
                            and 1997; and (iii) related Notes to Combined
                            Financial Statements.

     27.01                  Financial Data Schedule - Invitrogen Corporation

     27.02                  Financial Data Schedule - Research Genetics



                                       4






<PAGE>


                                  EXHIBIT 23.1

         CONSENT OF ARTHUR ANDERSEN LLP, INDEPENDENT PUBLIC ACCOUNTANTS

As independent public accountants, we hereby consent to the incorporation of our
report on Research Genetics, Inc. dated February 3, 2000, included in this Form
8-K, into Invitrogen Corporation's previously filed Registration Statements on
Form S-8 File No.'s 333-86531, 333-74061.

                                                   ARTHUR ANDERSEN LLP

Birmingham, Alabama
February 14, 2000


<PAGE>


                                  EXHIBIT 99.1


                                                                          [LOGO]


Financial and Investor Contacts:                          Media Contact:
Jim Glynn or Cheri Manis                                  Dan Peoples
Invitrogen Corporation                                    Broadgate Consultants
(760) 603-7200                                            (858) 552-8146


                         INVITROGEN CORPORATION REPORTS
                    1999 FULL YEAR AND FOURTH QUARTER RESULTS


         SAN DIEGO, CA, February 17, 2000 -- Invitrogen Corporation (NASDAQ:
IVGN) today announced results for its full year and fourth quarter ended
December 31, 1999.

         Net income for the year ended December 31, 1999, excluding
merger-related costs net of tax, was $9.8 million, up 131% compared with $4.2
million for 1998. Income available to common stockholders for 1999, excluding
merger-related costs, was $10.5 million, or $.57 per share, compared with $3.1
million, or $.23 per share, for the same period in 1998. Income available to
common stockholders in 1999 includes a $1.0 million incremental adjustment
reflecting the final redemption price for redeemable preferred stock that was
determinable upon the company's initial public offering in February.

         Merger-related costs of $4.4 million on a pre-tax basis were recognized
from the company's acquisition of NOVEX in the third quarter of 1999. Income
available to common stockholders for the year ended December 31, 1999, including
these merger-related costs net of tax, was $7.4 million, or $.40 per share.

         Revenues for the year ending in December 1999 were $68.3 million, up
27% from $53.7 million last year.

         Lyle C. Turner, Chairman and Chief Executive Officer, said, "Our
continued growth in both revenues and income reflects a combination of demand
growth, technology acquisition, entry into new markets, and new product
development. The results and accomplishments of last year are evidence of
Invitrogen's emerging leadership position in the genomics revolution."

         According to Turner, the highlights of 1999 included the company's
initial public offering in February, a secondary offering in November and the
acquisition of NOVEX in August. "NOVEX is a leading supplier of pre-cast
electrophoresis gels," said Turner, "and their product lines dovetail extremely
well with Invitrogen's. The merger establishes us as a leader in protein
electrophoresis and


<PAGE>


Page 2 -- Invitrogen Corporation Reports 1999 Full Year and Fourth Quarter
          Results

allows us to cross-sell products to existing customers of both companies and
address new markets utilizing our combined expertise."

         Turner added that on February 2, 2000, Invitrogen acquired Research
Genetics, Inc., a leading supplier of products and services for functional
genomics and gene-based drug discovery research. "By extending our product lines
into new areas of genomics, the NOVEX and Research Genetics acquisitions give us
the ability to serve customers from the earliest phases of gene identification
and target validation, and continue through the various stages of cloning,
protein expression and analysis," he said. The 1999 results of Research Genetics
are not included in Invitrogen's year-end results. However, the company today
filed pro forma combined financial information with the Securities and Exchange
Commission on Form 8-K/A.

         Turner also noted that during 1999 Invitrogen launched 65 products and
obtained 18 new technology licenses. At the end of last year, the company had
more than 85 technology licensing agreements covering approximately 200 patents.
"Our company has been able to grow rapidly thanks to an aggressive in-licensing
strategy that shortens product development times," added Turner. "The fact that
Invitrogen's products do not require FDA approval in the United States or
equivalent approvals in other countries further accelerates our time-to-market."

         Invitrogen's gross margins as a percent of revenues improved by more
than two percentage points during the year, from 64.2% in 1998 to 66.3% in 1999.
The improvement in gross margins resulted from higher absorption of overhead
costs, higher grant revenue, general price increases, lower royalty expenses and
cost reductions in shipping.

         Total operating expenses as a percentage of revenues, excluding
merger-related costs, declined from 52.3% in 1998 to 47.5% in 1999, reflecting
the fact that revenue growth continues to outpace spending for operations. At
the same time, the company said that sales and marketing, G&A and R&D categories
increased on an absolute dollar basis as the company expanded its resources to
support revenue growth, developed new products, and incurred additional expenses
in its first year as a public company. The company noted, however, that G&A
decreased in absolute dollars in the fourth quarter, reflecting workforce
reductions in September 1999 following the NOVEX acquisition.

         Net income for the quarter was $3.3 million, up 270% from the $.9
million recorded for the fourth quarter in 1998. Income available to common
stockholders for the fourth quarter was also $3.3 million, or $.16 per share, up
from $.6 million, or $.04 per share, reported for the same period in 1998.

         Revenues for the fourth quarter were $17 million, up 18% from the $14.4
million recorded for the fourth quarter in 1998. North American revenues grew
25% during the quarter to $11 million


<PAGE>


Page 3 -- Invitrogen Corporation Reports 1999 Full Year and Fourth Quarter
          Results


and European revenues grew 8% to $5 million. The company said revenue growth was
below that of recent quarters because of the negative impact of currency
conversion rates in Europe, an effect that was magnified by strong sales in
European countries. Excluding the effects of currency rates and slower growth in
the company's fine chemicals line, which was acquired as part of the NOVEX
acquisition, European revenues in the NOVEX and Invitrogen product lines grew
34% in the quarter.

         Invitrogen develops, manufactures and markets research tools in kit
form and provides other research products and services to corporate, academic
and government entities. These research kits simplify and improve gene cloning,
gene expression and gene analysis techniques and are used for genomics and
gene-based drug discovery, among other molecular biology activities. Founded in
1987, Invitrogen is headquartered in San Diego, California and has operations in
Huntsville, Alabama, Groningen, Netherlands, and Heidelberg, Germany.

         For more information about Invitrogen, visit the Invitrogen Web site at
www.invitrogen.com.

         Invitrogen will be hosting a conference call regarding these results at
11:00 a.m. Eastern Standard Time. To join the conference call, please dial
212-346-6502 after 10:55 a.m.


         CERTAIN STATEMENTS CONTAINED IN THIS PRESS RELEASE ARE CONSIDERED
"FORWARD-LOOKING STATEMENTS" WITHIN THE MEANING OF THE PRIVATE SECURITIES
LITIGATION REFORM ACT OF 1995, SUCH AS STATEMENTS RELATING TO EMERGING
LEADERSHIP, NEW PRODUCT MARKETS AND SELLING STRATEGIES, AND EXPANDED CUSTOMER
SERVICE OPPORTUNITIES ARE PROSPECTIVE. SUCH FORWARD-LOOKING STATEMENTS ARE
SUBJECT TO A NUMBER OF RISKS, UNCERTAINTIES AND OTHER FACTORS THAT COULD CAUSE
ACTUAL RESULTS TO DIFFER MATERIALLY FROM FUTURE RESULTS EXPRESSED OR IMPLIED BY
SUCH FORWARD-LOOKING STATEMENTS. POTENTIAL RISKS AND UNCERTAINTIES INCLUDE, BUT
ARE NOT LIMITED TO, WHETHER WE CAN MANAGE GROWTH AND SUCCESSFULLY INTEGRATE
RECENTLY ACQUIRED COMPANIES INTO OUR OPERATIONS, WHETHER WE ARE ABLE TO
SUCCESSFULLY DEVELOP AND COMMERCIALIZE NEW PRODUCTS AND SERVICES, AND WHETHER WE
CAN CONTINUE TO IDENTIFY, DEVELOP AND LICENSE NEW TECHNOLOGY, IN ADDITION TO
COMPETITION, AND OTHER RISKS AND UNCERTAINTIES DETAILED FROM TIME TO TIME IN THE
COMPANY'S SECURITIES AND EXCHANGE COMMISSION FILINGS.


<PAGE>


Page 4 -- Invitrogen Corporation Reports 1999 Full Year and Fourth Quarter
          Results


                     INVITROGEN CORPORATION AND SUBSIDIARIES
               INTERIM CONSOLIDATED CONDENSED STATEMENTS OF INCOME

<TABLE>
<CAPTION>

                                                                               THREE MONTHS ENDED         TWELVE MONTHS ENDED
                                                                                  DECEMBER 31,                DECEMBER 31,
(IN THOUSANDS, EXCEPT PER SHARE DATA)                                          1999         1998            1999        1998
                                                                               ----         ----            ----        ----
                                                                                   (UNAUDITED)
<S>                                                                         <C>          <C>             <C>          <C>
Revenues....................................................................$   17,024   $  14,448       $  68,312    $  53,660
Cost of Revenues............................................................     5,557       5,484          23,018       19,191
                                                                             ---------   ---------       ---------    ---------
   Gross margin.............................................................    11,467       8,964          45,294       34,469
Operating Expenses:
  Sales and marketing.......................................................     3,404       3,036          13,900       11,352
  General and administrative................................................     2,095       2,275           8,837        8,091
  Research and development..................................................     2,252       2,213           9,699        8,603
  Merger related costs......................................................         -           -           4,379            -
                                                                            ----------   ---------       ---------    ---------
     Total operating expenses...............................................     7,751       7,524          36,815       28,046
                                                                            ----------   ---------       ---------    ---------
       Income from operations...............................................     3,716       1,440           8,479        6,423
                                                                            ----------   ---------       ---------    ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions..............................         9         (53)            (90)          25
  Interest and other expense................................................       (22)        (52)           (244)        (249)
  Interest and other income.................................................     1,018         122           2,054          441
                                                                            ----------   ---------       ---------    ---------
                                                                                 1,005          17           1,720          217
                                                                            ----------   ---------       ---------    ---------
Income before provision for income taxes....................................     4,721       1,457          10,199        6,640
Provision for income taxes..................................................     1,377         552           3,534        2,410
                                                                            ----------   ---------       ---------    ---------
   NET INCOME...............................................................     3,344         905           6,665        4,230
   Less:  Preferred stock dividends.........................................         -        (225)           (163)        (900)
            Accretion of non-voting redeemable common stock.................         -         (54)            (74)        (204)
          Adjustment to beneficial conversion feature related to
           convertible preferred stock......................................         -           -             985            -
                                                                            ----------   ---------       ---------    ---------
       INCOME AVAILABLE TO COMMON STOCKHOLDERS..............................$    3,344  $      626       $   7,413    $   3,126
                                                                            ==========  ==========       =========    =========
EARNINGS PER SHARE:
  BASIC.....................................................................$     0.18   $    0.05       $    0.47    $    0.26
                                                                            ==========   =========       =========    =========
  DILUTED...................................................................$     0.16   $    0.04       $    0.40    $    0.23
                                                                            ==========   =========       =========    =========
Weighted average shares used in per share calculation:
  Basic.....................................................................    18,179      12,144          15,869       12,152
  Diluted...................................................................    20,777      14,586          18,429       13,883

PRO FORMA EXCLUDING MERGER RELATED COSTS, NET OF TAX:
Net income..................................................................$    3,344   $     905       $   6,665    $   4,230
  Add back non-recurring merger-related costs...............................         -           -           4,379            -
  Less related tax benefit..................................................         -           -          (1,255)           -
                                                                            ----------   ---------       ----------   ---------
   PRO FORMA NET INCOME.....................................................$    3,344  $      905       $   9,789    $   4,230
                                                                            ==========  ==========       =========    =========
    PRO FORMA INCOME AVAILABLE TO COMMON STOCKHOLDERS.......................$    3,344  $      626       $  10,537    $   3,126
                                                                            ==========  ==========       =========    =========
PRO FORMA EARNINGS PER SHARE:
  BASIC.....................................................................$     0.18   $    0.05       $    0.66    $    0.26
                                                                            ==========   =========       =========    =========
  DILUTED...................................................................$     0.16   $    0.04       $    0.57    $    0.23
                                                                            ==========   =========       =========    =========

</TABLE>


<PAGE>


Page 5 -- Invitrogen Corporation Reports 1999 Full Year and Fourth Quarter
          Results


                     INVITROGEN CORPORATION AND SUBSIDIARIES
                      CONSOLIDATED CONDENSED BALANCE SHEETS

<TABLE>
<CAPTION>

                                                                         DECEMBER 31,         DECEMBER 31,
(IN THOUSANDS)                                                               1999                 1998
                                                                         ------------         ------------
<S>                                                                       <C>                  <C>
                                ASSETS
Current Assets:
   Cash, cash equivalents and investments..............................   $   102,220          $     6,530
   Accounts and notes receivable, net of allowance.....................         7,027                5,778
   Inventories.........................................................         5,344                5,374
   Other current assets................................................         9,004                2,061
                                                                          -----------          -----------
     Total current assets..............................................       123,595               19,743
Property and equipment, net............................................         8,400               10,036
Intangible assets, net.................................................         3,651                1,708
Other assets...........................................................           346                  563
                                                                          -----------          -----------
   Total Assets........................................................   $   135,992          $    32,050
                                                                          ===========          ===========
                 LIABILITIES AND STOCKHOLDERS' EQUITY
Current Liabilities:
   Notes payable to bank...............................................   $        35          $       779
   Current portion of long term obligations............................         1,011                  995
   Accounts payable....................................................         2,351                3,106
   Accrued expenses and other current liabilities......................         5,172                2,836
   Income taxes payable................................................         1,080                  802
                                                                          -----------          -----------
     Total current liabilities.........................................         9,649                8,518
Non-current liabilities................................................           721                1,116
Preferred and redeemable non-voting common stock issues................             -               17,740
Stockholders' equity...................................................       125,622                4,676
                                                                          -----------          -----------
   Total Liabilities and Stockholders' Equity..........................   $   135,992          $    32,050
                                                                          ===========          ===========

</TABLE>

                                      # # #




<PAGE>


                                                                   EXHIBIT 99.2

    RESEARCH GENETICS, INCORPORATED

    Financial Statements
    As of December 31, 1999 and 1998
    Together with Report of Independent Public Accountants


<PAGE>



REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To Invitrogen Corporation:

We have audited the accompanying balance sheets of Research Genetics,
Incorporated, an Alabama corporation, as of December 31, 1999 and 1998, and the
related statements of income, shareholders' equity and cash flows for the years
then ended. These financial statements are the responsibility of the Company's
management. Our responsibility is to express an opinion on these financial
statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to obtain reasonable assurance about whether the financial statements are free
of material misstatement. An audit includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial statements. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.

In our opinion, the financial statements referred to above present fairly, in
all material respects, the financial position of Research Genetics, Incorporated
as of December 31, 1999 and 1998, and the results of its operations and its cash
flows for the years then ended, in conformity with accounting principles
generally accepted in the United States.




                                               ARTHUR ANDERSEN LLP

Birmingham, Alabama
February 3, 2000


<PAGE>


RESEARCH GENETICS, INC.

Balance Sheets  - December 31, 1999 and 1998

<TABLE>
<CAPTION>

                                     ASSETS

                                                                                     1999                  1998
                                                                                 ------------          ------------
<S>                                                                              <C>                   <C>
Current assets:
   Cash                                                                          $      1,443          $     13,185
   Accounts receivable, net of allowance for doubtful accounts of
     $400,000 and $350,000, respectively                                            4,308,776             2,728,952
   Inventory                                                                        2,146,208               572,941
   Prepaid and other assets                                                           207,318               139,202
   Deferred income taxes                                                              344,511               289,562
   Note receivable                                                                    183,000                   -
                                                                                 ------------          ------------
              Total current assets                                                  7,191,256             3,743,842
                                                                                 ------------          ------------
Property and equipment, net                                                        12,909,695             8,770,317
                                                                                 ------------          ------------
Other assets:
   Deposits and other                                                                 210,314               604,171
   Intangibles, net                                                                   820,311               271,943
   Note receivable                                                                       -                  183,000
                                                                                 ------------          ------------
              Total other assets                                                    1,030,625             1,059,114
                                                                                 ------------          ------------
Total assets                                                                     $ 21,131,576          $ 13,573,273
                                                                                 ============          ============
</TABLE>

                                   (continued)


<PAGE>


RESEARCH GENETICS, INC.

Balance Sheets  - December 31, 1999 and 1998

(continued)

<TABLE>
<CAPTION>

                      LIABILITIES AND SHAREHOLDERS' EQUITY

                                                                                     1999                 1998
                                                                                 ------------          ------------
<S>                                                                              <C>                   <C>
Current liabilities:
   Lines of credit                                                               $  1,349,563          $    190,000
   Accounts payable                                                                 1,950,164             1,346,279
   Accrued expenses                                                                   456,854               252,734
   Income tax payable                                                                 600,468               199,959
   Current portion of industrial development bonds                                    255,000               240,000
   Current portion of notes payable                                                 3,975,815               562,347
                                                                                 ------------          ------------
              Total current liabilities                                             8,587,864             2,791,319
                                                                                 ------------          ------------
Other liabilities:
   Deferred income taxes                                                              438,737               322,435
   Notes payable, net of current portion                                            3,909,825             4,037,130
   Industrial development bonds, net of current portion                             2,625,000             2,880,000
                                                                                 ------------          ------------
              Total other liabilities                                               6,973,562             7,239,565
                                                                                 ------------          ------------
              Total liabilities                                                    15,561,426            10,030,884
                                                                                 ------------          ------------

Shareholders' equity:

   Common stock, $.10 par, 100,000 shares authorized, 50,000
      issued and outstanding                                                            5,000                 5,000
   Additional paid-in capital                                                       1,800,180             1,719,515
   Retained earnings                                                                3,764,970             1,817,874
                                                                                 ------------          ------------
              Total shareholders' equity                                            5,570,150             3,542,389
                                                                                 ------------          ------------
Total liabilities and shareholders' equity                                       $ 21,131,576          $ 13,573,273
                                                                                 ============          ============
</TABLE>
<PAGE>



RESEARCH GENETICS, INC.

Statements of Income
For the Years Ended December 31, 1999 and 1998

<TABLE>
<CAPTION>


                                                                                      1999                   1998
                                                                                  -----------           -----------
<S>                                                                               <C>                   <C>
Sales, net                                                                        $24,580,843           $17,006,280

     Cost of sales                                                                  9,674,271             7,282,954
                                                                                  -----------           -----------
Gross profit                                                                       14,906,572             9,723,326

     Selling expenses                                                               2,335,024             1,812,571

     Research and development expenses                                              5,010,812             2,635,309

     Operating expenses                                                             3,473,525             3,005,939
                                                                                  -----------           -----------
Income from operations                                                              4,087,211             2,269,507

     Other (expense) income:

       Interest and other income                                                         (139)              258,829
       Interest expense                                                              (446,600)             (455,521)
       Loss on investment                                                                   -              (205,000)
                                                                                  -----------           -----------
       Total other expense                                                           (446,739)             (401,692)
                                                                                  -----------           -----------
Income before taxes                                                                 3,640,472             1,867,815

     Provision for income taxes                                                     1,245,896               578,695
                                                                                  -----------           -----------
Net income                                                                        $ 2,394,576           $ 1,289,120
                                                                                  ===========           ===========
</TABLE>

<PAGE>



RESEARCH GENETICS, INC.

Statements of Shareholders' Equity
For the Years Ended December 31, 1999 and 1998

<TABLE>
<CAPTION>


                                                       Common Stock                Additional
                                                    ------------------               Paid-in            Retained
                                                   Shares          Amount            Capital            Earnings        Total
                                                   ------          ------            -------            --------        -----
<S>                                               <C>              <C>            <C>                  <C>              <C>
Balance, December 31, 1997                        50,000           $5,000         $ 1,514,515          $1,186,084       $2,705,599

   Contribution                                      -                -               205,000                 -            205,000
   Dividends paid                                    -                -                   -              (657,330)        (657,330)
   Net income                                        -                -                   -             1,289,120        1,289,120
                                                  ------           ------          ----------          ----------       ----------
Balance, December 31, 1998                        50,000            5,000           1,719,515           1,817,874        3,542,389

   Contributions                                     -                -                80,665                 -             80,665
   Dividends paid                                    -                -                   -              (447,480)        (447,480)
   Net income                                        -                -                   -             2,394,576        2,394,576
                                                  ------           ------          ----------          ----------       ----------
Balance, December 31, 1999                        50,000           $5,000          $1,800,180          $3,764,970       $5,570,150
                                                  ======           ======          ==========          ==========       ==========
</TABLE>

<PAGE>



RESEARCH GENETICS, INC.

Statements of Cash Flows
For the Years Ended December 31, 1999 and 1998

<TABLE>

                                                                                          1999                  1998
                                                                                       -----------           -----------
<S>                                                                                   <C>                    <C>
Cash flows from operating activities:
   Net income                                                                         $  2,394,576           $ 1,289,120
   Adjustments to reconcile net income to net cash provided by operating
     activities:
       Depreciation and amortization                                                     1,746,499             1,270,459
       Gains on sales of property and equipment                                             (3,649)               (4,287)
   Changes in:
       Accounts receivable                                                              (1,579,824)             (482,130)
       Inventory                                                                        (1,573,267)             (265,287)
       Prepaid and other assets                                                            (68,116)              (48,517)
       Deferred income taxes                                                               (54,949)             (149,602)
       Deposits and other                                                                  393,857              (351,493)
       Accounts payable                                                                    603,885               784,832
       Accrued expenses                                                                    204,120                70,887
       Income tax payable                                                                  400,509                27,221
       Deferred tax liability                                                              116,302                76,610
                                                                                       -----------           -----------
              Net cash provided by operating activities                                  2,579,943             2,217,813
                                                                                       -----------           -----------
Cash flows from investing activities:
   Property and equipment purchased                                                     (5,669,509)           (3,040,827)
   Proceeds from sales of property and equipment                                            44,868                90,718
   Purchase of intangibles                                                                (805,955)             (349,630)
                                                                                       -----------           -----------
              Net cash used by investing activities                                     (6,430,596)           (3,299,739)
                                                                                       -----------           -----------
Cash flows from financing activities:
   Dividends paid                                                                         (447,480)             (657,330)
   Capital contribution                                                                     80,665               205,000
   Bond payments                                                                          (240,000)             (225,000)
   Proceeds from notes payable                                                           3,782,440             3,408,165
   Principal payments on notes payable                                                    (496,277)           (1,267,779)
   Proceeds from lines of credit                                                        12,250,663             9,865,556
   Payments on lines of credit                                                         (11,091,100)          (10,249,350)
                                                                                       -----------           -----------
              Net cash provided by financing activities                                  3,838,911             1,079,262
                                                                                       -----------           -----------
Net decrease in cash balance                                                               (11,742)               (2,664)

Beginning cash balance                                                                      13,185                15,849
                                                                                       -----------           -----------
Ending cash balance                                                                   $      1,443          $     13,185
                                                                                      ============           ===========
</TABLE>

<PAGE>



RESEARCH GENETICS, INC.

Notes to Financial Statements
December 31, 1999 and 1998

1.     BUSINESS ACTIVITY AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

       BUSINESS ACTIVITY

       Research Genetics, Incorporated (the "Company") was incorporated in the
       state of Alabama on June 1, 1994. The Company operates in one business
       segment which develops, manufactures and sells products designed to
       facilitate molecular biology research. The Company sells its products to
       researchers at universities, corporations, and research institutions
       throughout North America, the Pacific Rim and Europe.

       CONCENTRATIONS OF CUSTOMERS RISK

       Substantially all of the Company's revenues during the years ended
       December 31, 1999 and 1998, were derived from university and research
       institutions which management believes are, to some degree, directly or
       indirectly supported by the U.S. Government. A change in current research
       fundings, particularly with respect to the National Institutes of Health
       and the National Cancer Institute, may have an adverse impact on the
       Company's future results of operations.

       REVENUE RECOGNITION

       Revenues from product sales are recognized upon shipment to the customer.
       The Company generally does not receive material upfront fees; those that
       are received are deferred and recognized when products are shipped to the
       customer or when services are rendered. Grant revenue is recorded as
       earned, as defined within the specific agreements and is not refundable.
       Grant revenue was $8,216 and $58,505 in 1999 and 1998, respectively. Cost
       of grant revenue is included in research and development. Royalty revenue
       is recognized when earned, generally upon the receipt of cash, and is not
       refundable.

       CASH AND CASH EQUIVALENTS

       The Company considers all highly liquid investments with an original
       maturity of three months or less to be cash equivalents. Cash equivalents
       at December 31, 1999 and 1998 consist primarily of funds held by an FDIC
       insured financial institution.

       INVENTORIES

       Inventories are stated at lower of cost (first-in, first-out method) or
       market. The Company reviews the components of its inventory on a
       quarterly basis for excess, obsolete and impaired inventory and makes
       appropriate dispositions as obsolete stock is identified.

       PROPERTY AND EQUIPMENT

       Property and equipment is stated at cost and depreciated over the
       estimated useful lives of the assets (3 to 39 years) using the
       straight-line method. Amortization of leasehold improvements is computed
       on the straight-line method over the shorter of the lease term or the
       estimated useful lives of the assets. Maintenance and repairs are charged
       to operations as incurred. When assets are sold, or otherwise disposed
       of, the cost and related accumulated depreciation are removed from the
       accounts and any gain or loss is included in operations.

       INTANGIBLES

       Intangibles consist of genome libraries. The Company amortizes these
       genome libraries on a straight line basis over three years.

       LONG-LIVED ASSETS

       The Company has adopted Statement of Financial Accounting Standards No.
       121, "Accounting for the Impairment of Long-Lived Assets". The statement
       requires that long-lived assets and certain identifiable intangibles to
       be held and used by an entity be reviewed for possible impairment
       whenever events or changes in circumstances indicate that the carrying
       amount of an asset may not be fully recoverable. The Company periodically
       re-evaluates the original assumptions and rationale utilized in the
       establishment of the carrying value and estimated lives of its long-lived
       assets. The criteria used for these evaluations include management's
       estimate of the asset's continuing ability to generate income from
       operations and positive cash
<PAGE>


       flow in future periods as well as the strategic significance of any
       intangible asset in the Company's business objectives.

       RESEARCH AND DEVELOPMENT COSTS

       All research and development costs are charged to operations as incurred.

       FAIR VALUE OF FINANCIAL INSTRUMENTS

       The carrying amounts of all receivables, payables and accrued balances
       approximate fair value due to the short-term nature of such instruments.
       The carrying amount of the line of credit approximates fair value due to
       the floating rate on such instruments. The carrying value of long-term
       debt with fixed payment terms approximates fair value.

       INCOME TAXES

       The Company uses the liability method of accounting for income taxes in
       accordance with Statement of Financial Statement Accounting Standards No.
       109, "Accounting for Income Taxes". Deferred income taxes reflect the net
       tax effects of temporary differences between the carrying amounts of
       assets and liabilities for financial reporting purposes and the amounts
       used for income tax purposes, using enacted tax rates in effect for the
       year in which the differences are expected to reverse. Valuation
       allowances are established, when necessary, to reduce deferred tax assets
       to the amount expected to be realized.

       USE OF ESTIMATES

       The preparation of financial statements in conformity with generally
       accepted accounting principles requires management to make estimates and
       assumptions that affect the reported amounts of assets and liabilities
       and disclosures of contingent assets and liabilities at the date of the
       financial statements and the reported amounts of revenues and expenses
       during the reporting period. Actual results could differ from those
       estimates.

       RECENT ACCOUNTING PRONOUNCEMENTS

       In December, 1999, the Securities and Exchange Commission ("SEC") issued
       Staff Accounting Bulletin (SAB) No. 101, "Revenue Recognition in
       Financial Statements". This SAB summarizes the SEC's view in applying
       generally accepted accounting principles to revenue recognition in
       financial statements. This SAB is effective for all registrants during
       the first quarter of fiscal 2000. Management has reviewed the impact of
       SAB 101 on the Company's financial statements, and does not believe that
       its adoption will have a material impact on the Company's financial
       statements.

2.     RELATED PARTY TRANSACTIONS

       Related party transactions consist of minor pass-through arrangements
       with various start-up biotech companies in which the Company's chief
       executive officer and majority shareholder holds a nominal equity
       interest.

3.     INVENTORIES

       Inventories include material, labor and overhead costs, and consist of
       the following at December 31, 1999 and 1998:

<TABLE>
<CAPTION>


                                                                 1999                1998
                                                               --------            -------
              <S>                                            <C>                   <C>
              Raw materials and components                   $  557,097            $177,294
              Work in process                                   225,580              98,547
              Finished goods                                  1,363,531             297,100
                                                             ----------            --------
                                                             $2,146,208            $572,941
                                                             ==========            ========
</TABLE>

<PAGE>


4.       PROPERTY AND EQUIPMENT

       Property and equipment consist of the following at December 31, 1999 and
1998:

<TABLE>
<CAPTION>

                                                                           1999                 1998
                                                                       ------------         -----------
              <S>                                                     <C>                   <C>
              Land                                                    $   5,406,865         $ 1,891,350
              Building                                                    3,278,264           3,126,655
              Machinery and equipment                                     9,012,866           8,009,733
              Leasehold improvements                                      1,166,805             548,692
                                                                       ------------         -----------
                                                                         18,864,800          13,576,430
              Accumulated depreciation and amortization                  (5,955,105)         (4,806,113)
                                                                       ------------         -----------
                                                                       $ 12,909,695         $ 8,770,317
                                                                       ============         ===========
</TABLE>


5.     NOTES RECEIVABLE

       The Company holds two notes receivable totaling $108,000 and $75,000 as
       of December 31, 1999 and 1998, respectively. The promissory notes
       originated in 1996, are unsecured, bear annual interest of eight percent
       and are due in full in September 2000.

6.     RETIREMENT PLAN

       The Company has a 401(k) profit sharing plan that covers all employees
       who meet the minimum participation requirements. For those employees
       participating, annual compensation may be deferred up to the maximum
       prescribed by the Internal Revenue Code. The Company contributes an
       amount equal to 50% of the first 5% of the participating employee's
       pre-tax contribution. Matching contributions for the year ended December
       31, 1999 and 1998 were $91,010 and $71,217, respectively.

7.     LINES OF CREDIT AND NOTES PAYABLE

<TABLE>
<CAPTION>

                                                                                                   December 31,        December 31,
                                                                                                       1999               1998
                                                                                                   -----------         ------------
       <S>                                                                                         <C>                 <C>
       SouthTrust Bank,  $1,000,000 line of credit  available,  payable
       June 2000, plus interest at a fixed  rate of 7.25%.  The line of
       credit  note is  collateralized  by a  Security  Agreement covered
       by property and equipment.                                                                  $   958,785         $   543,115

       SouthTrust Bank,  $1,500,000 line of credit available,  payable
       January 1999, plus interest at the  bank's  base  rate,  7.75%.  The
       line of  credit  note is  collateralized  by a  Security Agreement
       covered by equipment, inventory and accounts receivable.                                        380,000             190,000

       SouthTrust Bank, $1,000,000 line of credit available, payable February
       2000, plus interest at the bank's base rate, 8.1%. The line of credit
       note is collateralized by a Security Agreement covered by equipment,
       inventory and accounts receivable.                                                              794,979                -

       SouthTrust  Bank, note payable in monthly  installments of $15,800
       through June 1999 including interest at 7.75%,  collateralized  by a
       General Security  Agreement  covered by machinery and equipment.                                  -                 121,836

       SouthTrust  Bank,  note  payable  in  monthly  installments  of $9,282
       through  October  2008 including interest at 7.75%, collateralized by a
       General Security Agreement covered by land.                                                   1,538,637           1,457,488

       SouthTrust Bank, note payable in March 2000 including  interest at 7.5%,
       collateralized  by a General Security Agreement covered by land.                              3,500,000                -
</TABLE>

<PAGE>


<TABLE>
<CAPTION>

                                                                                                    December 31,     December 31,
                                                                                                        1999             1998
                                                                                                   ------------      ------------
       <S>                                                                                          <C>              <C>
       SBA & SouthTrust  Bank,  note  payable in monthly  installments  of $2,250
       through May 2002 including interest at 7.75%, collateralized by mortgage on
       building,  machinery and equipment A life  insurance policy  of $200,000  is
       also pledged as security                                                                         92,768             111,665

       SouthTrust Bank, note payable in monthly installments of $11,465 through
       June 2003 including interest of 8.5%, collateralized by a General Security
       Agreement covered by machinery and equipment                                                    418,394             515,341

       SouthTrust Bank, note payable in monthly installments of $10,578 through
       June 2004 including interest of 8.75%, collateralized by equipment                              469,532             550,860

       SouthTrust Bank, note payable in monthly installments of $18,929
       through October 2005 including  interest of 7.0%. The note is  collateralized
       by a Security  Agreement  covered by property and equipment                                   1,082,108           1,226,847

       Perkin-Elmer,  note payable in monthly  installments of $6,511 through
       December 1999 including interest at 11.6%, collateralized by equipment                             -                 55,860

       IKON  Capital  Resource,  note  payable in monthly  installments  of $503
       through  March 1999 including interest at 18.2%, collateralized by equipment                       -                  1,465

       Note Payable to an individual due January 2002, interest at 9.6% payable
       monthly, unsecured                                                                                 -                 15,000
                                                                                                   -----------         -----------
                                                                                                     9,235,203           4,789,477

       Less Current Portion of Lines of Credit and Notes Payable                                    (5,325,378)           (752,347)
                                                                                                   -----------         -----------
       Long-Term Portion of Lines of Credit and Notes Payable                                      $ 3,909,825         $ 4,037,130
                                                                                                   ===========         ===========
</TABLE>

       The long-term portion of the lines of credit and notes payable mature as
follows:

<TABLE>
<CAPTION>

             YEAR ENDED DECEMBER 31,
             ----------------------
             <S>                                          <C>
                      2000                                $5,325,378
                      2001                                   695,825
                      2002                                   743,459
                      2003                                   729,073
                      2004                                   541,752
                   Thereafter                              1,199,716
                                                          ----------
                                                          $9,235,203
                                                          ==========
</TABLE>

       Substantially all of the Company's accounts receivable, inventory,
       property and equipment are pledged as security on the above notes.

       The above notes contain various financial covenants. As of December 31,
       1999 and 1998, the Company was in compliance with its various financial
       covenants.

8.     BONDS PAYABLE

       The Company has an outstanding loan agreement with the State Industrial
       Development Authority, a public corporation of the State of Alabama, for
       the repayment of certain Variable Rate Industrial Development Revenue
       Bonds issued for the benefit of the Company. The note securing the loan
       agreement bears interest at a rate which varies weekly with prevailing
       market conditions. Interest is payable monthly and principal is due
       annually on January 1. The principal amount of the bonds was $2,880,000
       at December 31, 1999.

       In addition, the Company has a reimbursement agreement with SouthTrust
       Bank which provides a letter of credit related to the above mentioned
       bonds. The amount of such letter of credit was $2,625,000 at December 31,


<PAGE>


       1999. The Company pays an annual fee of 1.25% of the outstanding letter
       of credit. The credit agreement provides for certain financial covenants
       to be met through the year 2000. This letter of credit is personally
       guaranteed by the Company's majority stockholder. The Company also pays
       an annual remarketing fee equal to 0.12% of the outstanding bond
       principal balance.

       Improvements and equipment acquired with the bond proceeds become the
       property of the Industrial Development Board of the City of Huntsville.
       The Company has entered into a lease arrangement with the Board whereby
       the property is leased for one dollar per year through January 1, 2008.
       The Company has an option to purchase the property from the Board for one
       hundred dollars.

       The bonds mature as follows:

<TABLE>
<CAPTION>

                  YEAR ENDED DECEMBER 31
                  ----------------------
                       <S>                                 <C>
                            2000                           $   255,000
                            2001                               270,000
                            2002                               280,000
                            2003                               295,000
                            2004                               310,000
                       Thereafter                            1,470,000
                                                           -----------
                                                           $ 2,880,000
                                                           ===========
</TABLE>

9.     INCOME TAXES

       Significant components of the Company's deferred tax assets and
       liabilities are as follows at December 31, 1999 and 1998:

<TABLE>
<CAPTION>
                                                                              1999               1998
                                                                           ---------          ---------
           <S>                                                             <C>                <C>
           Deferred tax assets:
              Various accruals                                             $  93,000          $  68,000
              Bad debt reserve and other reserves                            160,000            141,000
              Other                                                           92,000             81,000
                                                                           ---------          ---------
           Total deferred tax assets                                         345,000            290,000

           Deferred tax liabilities:
              Depreciation and amortization                                 (439,000)          (322,000)
                                                                           ---------          ---------
           Net deferred tax liability                                      $ (94,000)         $ (32,000)
                                                                           =========          =========
</TABLE>

       The provision for income taxes is based on results of operations, reduced
       by the available research and development credit and state tax credit,
       and consists of the following for the years ended December 31, 1999 and
       1998:

<TABLE>
<CAPTION>

                                                                            1999               1998
                                                                         -----------         --------
           <S>                                                            <C>                <C>
           Current:
              Federal                                                    $ 1,177,000         $454,000
              State                                                          131,000           51,000
                                                                         -----------         --------
           Total current provision                                         1,308,000          505,000

           Deferred:
              Federal                                                        (56,000)          68,000
              State                                                           (6,000)           6,000
                                                                         -----------         --------
           Total deferred provision                                          (62,000)          74,000
                                                                         -----------         --------
           Total provision                                               $ 1,246,000         $579,000
                                                                         ===========         ========
</TABLE>


<PAGE>


       The provision for income taxes differs from the amount computed by
       applying the federal statutory rate to the Company's income before the
       provision for income taxes as follows for the years ended December 31,
       1999 and 1998:

<TABLE>
<CAPTION>

                                                                             1999               1998
                                                                         -------------      ------------
              <S>                                                         <C>               <C>
              Federal tax provision at statutory rate                     $ 1,238,000       $  635,000
              State tax, net of federal benefit                               120,000           62,000
              Research and development and other credits                     (132,000)        (132,000)
              Other                                                            20,000           14,000
                                                                          -----------       ----------
              Provision for income taxes                                  $ 1,246,000       $  579,000
                                                                          ===========       ==========
</TABLE>

10.    COMMITMENTS AND CONTINGENCIES

       The Company is at times subject to pending and threatened legal actions
       that arise out of the normal course of business. In the opinion of
       management, based in part on the advise of legal counsel, the ultimate
       disposition of these matters will not have a material adverse effect on
       the financial position or results of operations of the Company.

11.    SUBSEQUENT EVENT

       On February 2, 2000, the Company was acquired by Invitrogen Corporation
       in exchange for 3,200,000 shares of Invitrogen common stock.


<PAGE>


                                  EXHIBIT 99.4

          INVITROGEN UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS

The following unaudited pro forma combined balance sheet as of December 31,
1999, illustrates the effect of the merger as if it had occurred on December 31,
1999. The following unaudited pro forma combined statements of income for the
three years ended December 31, 1999, illustrate the effect of the merger as if
it had occurred on January 1, 1997. There were no material differences between
the accounting policies of Invitrogen and Research Genetics and, therefore, no
conforming of accounting policy adjustments have been made to the pro forma
financial statements. The unaudited pro forma combined statements of income for
the three years ended December 31, 1999 include both Invitrogen's and Research
Genetics' financial data for these same periods.

The pro forma combined financial statements are presented for comparative
purposes only and are not necessarily indicative of the combined financial
position or results of operations of future periods or the results that actually
would have been realized had Invitrogen and Research Genetics been a single
entity during the periods presented.

Pursuant to the terms of the merger, each share of Research Genetics stock was
converted into the right to receive 64 shares of Invitrogen. The pro forma
combined financial statements have been derived from the respective historical
audited consolidated financial statements of Invitrogen and Research Genetics
and should be read in conjunction with such financial statements and the notes
thereto that are incorporated herein by reference.


<PAGE>


                                   INVITROGEN CORPORATION AND RESEARCH GENETICS
                                    UNAUDITED PRO FORMA COMBINED BALANCE SHEET

                                                 DECEMBER 31, 1999

                                                  (IN THOUSANDS)


<TABLE>
<CAPTION>

                                                                              HISTORICAL
                                                            HISTORICAL         RESEARCH          PRO FORMA              PRO FORMA
                                                            INVITROGEN         GENETICS         ADJUSTMENTS             COMBINED
                                                          --------------    --------------    --------------         --------------
<S>                                                         <C>               <C>               <C>                     <C>

ASSETS
Current Assets:
    Cash and cash equivalents .......................        $   102,220       $         1       $         -            $   102,221
    Accounts and notes receivable ...................              7,027             4,309                (1) (2)            11,335
    Inventories .....................................              5,344             2,146                 -                  7,490
    Income taxes receivable .........................              4,495                 -                 -                  4,495
    Deferred income taxes ...........................              3,216               345                 -                  3,561
    Prepaid expenses and other current assets .......              1,293               390                 -                  1,683
                                                          --------------    --------------    --------------         --------------
        Total current assets ........................            123,595             7,191                (1)               130,785
Property, plant and equipment, net ..................              8,400            12,910                                   21,310
Intangible assets, net ..............................              3,651               820                 -                  4,471
Other assets ........................................                346               211                 -                    557
                                                          --------------    --------------    --------------         --------------
Total Assets ........................................        $   135,992       $    21,132       $        (1)           $   157,123
                                                          ==============    ==============    ==============         ==============

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
    Note payable to bank ............................        $        35       $     1,350       $         -            $     1,385
    Current portion of long-term obligations ........              1,011             4,231                 -                  5,242
    Accounts payable ................................              2,351             1,950                (1) (2)             4,300
    Accrued expenses ................................              5,172               457             3,920  (4)             9,549
    Income taxes payable ............................              1,080               600               (91) (4)             1,589
                                                          --------------    --------------    --------------         --------------
        Total current liabilities ...................              9,649             8,588             3,828                 22,065
                                                          --------------    --------------    --------------         --------------

Long-term obligations, less current maturities ......                721             6,535                 -                  7,256
Deferred income taxes ...............................                  -               439                 -                    439

Stockholders' Equity:
    Common stock, par value..........................                191                 5                27  (3)               223
    Other stockholders' equity.......................            125,431             5,565            (3,856) (3)(4)        127,140
                                                          --------------    --------------    --------------         --------------

Total stockholders' equity ..........................            125,622             5,570            (3,829)               127,363
                                                          --------------    --------------    --------------         --------------
Total Liabilities and Stockholders' Equity ..........        $   135,992       $    21,132       $        (1)           $   157,123
                                                          ==============    ==============    ==============         ==============
</TABLE>
         See Notes to Unaudited Pro Forma Combined Financial Statements.


<PAGE>


                  INVITROGEN CORPORATION AND RESEARCH GENETICS
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME

                          YEAR ENDED DECEMBER 31, 1999

                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                                           HISTORICAL
                                                            HISTORICAL      RESEARCH       PRO FORMA          PRO FORMA
                                                            INVITROGEN      GENETICS      ADJUSTMENTS          COMBINED
                                                             ---------      ---------       ----------         ---------
<S>                                                         <C>            <C>            <C>                 <C>
Revenues.................................................     $ 68,312       $ 24,581        $    (13) (2)      $ 92,880
Cost of Revenues.........................................       23,018          9,674              (2) (2)        32,690
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       45,294         14,907             (11)            60,190
Operating Expenses:
  Sales and marketing....................................       13,900          2,335               -             16,235
  General and administrative.............................        8,837          3,474               -             12,311
  Research and development...............................        9,699          5,011             (11) (2)        14,699
  Merger related costs...................................        4,379              -               -              4,379
                                                             ---------      ---------       ---------          ---------
     Total operating expenses............................       36,815         10,820             (11)            47,624
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        8,479          4,087               -             12,566
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........          (90)             -               -                (90)
  Interest and other expense.............................         (244)          (447)              -               (691)
  Interest and other income..............................        2,054              -               -              2,054
                                                             ---------      ----------      ---------          ---------
                                                                 1,720           (447)              -              1,273
                                                             ---------      ----------      ---------          ---------
Income before provision for income taxes.................       10,199          3,640               -             13,839
Provision for income taxes...............................        3,534          1,245              -               4,779
                                                             ---------      ---------       ---------          ---------
  Net Income.............................................        6,665          2,395               -              9,060

Less:  Preferred stock dividends.........................         (163)             -               -               (163)
      Accretion of non-voting redeemable common stock....          (74)             -               -                (74)
      Adjustment to beneficial conversion feature related
        to convertible preferred stock...................          985              -               -                985
                                                             ---------      ---------       ---------          ---------
       Income available to common stockholders...........     $  7,413       $  2,395        $      -           $  9,808
                                                             =========      =========       =========          =========
Earnings per share:
  Basic..................................................     $   0.47       $  47.90                           $   0.51
                                                             =========      =========       =========          =========
  Diluted................................................     $   0.40       $  47.90                           $   0.45
                                                             =========      =========                          =========
Weighted average shares used in per share calculation:
  Basic..................................................       15,869             50                             19,069   (3)
  Diluted................................................       18,429             50                             21,629   (3)
</TABLE>


         See Notes to Unaudited Pro Forma Combined Financial Statements.


<PAGE>



                  INVITROGEN CORPORATION AND RESEARCH GENETICS
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME

                          YEAR ENDED DECEMBER 31, 1998

                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>

                                                                           HISTORICAL
                                                            HISTORICAL      RESEARCH       PRO FORMA          PRO FORMA
                                                            INVITROGEN      GENETICS      ADJUSTMENTS          COMBINED
                                                             ---------      ---------       ----------         ---------
<S>                                                         <C>            <C>            <C>                 <C>
Revenues.................................................     $ 53,660       $ 17,006        $    (99) (2)      $ 70,567
Cost of Revenues.........................................       19,191          7,283             (62) (2)        26,412
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       34,469          9,723             (37)            44,155
Operating Expenses:
  Sales and marketing....................................       11,352          1,813               -             13,165
  General and administrative.............................        8,091          3,006               -             11,097
  Research and development...............................        8,603          2,635             (37) (2)        11,201
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................       28,046          7,454             (37)            35,463
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        6,423          2,269               -              8,692
                                                             ---------      ---------       ---------          ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........           25              -               -                 25
  Interest and other expense.............................         (249)          (661)              -               (910)
  Interest and other income..............................          441            259               -                700
                                                             ---------      ---------       ---------          ---------
                                                                   217           (402)              -               (185)
                                                             ---------      ----------      ---------          ----------
Income before provision for income taxes.................        6,640          1,867               -              8,507
Provision for income taxes...............................        2,410            578               -              2,988
                                                              ---------      --------        --------           ---------
  Net income.............................................        4,230          1,289               -              5,519

Less:  Preferred stock dividends.........................         (900)             -               -               (900)
      Accretion of non-voting redeemable common stock....         (204)             -               -               (204)
                                                             ---------      ---------       ---------          ---------
       Income available to common stockholders...........     $  3,126       $  1,289        $      -           $  4,415
                                                              ========       ========        ========           ========
Earnings per share:
  Basic..................................................     $   0.26       $  25.78                           $   0.29
                                                              ========       ========                           ========
  Diluted................................................     $   0.23       $  25.78                           $   0.26
                                                              ========       ========                           ========
Weighted average shares used in per share calculation:
  Basic..................................................       12,152             50                             15,352   (3)
  Diluted................................................       13,883             50                             17,083   (3)
</TABLE>

         See Notes to Unaudited Pro Forma Combined Financial Statements.


<PAGE>


                  INVITROGEN CORPORATION AND RESEARCH GENETICS
                UNAUDITED PRO FORMA COMBINED STATEMENTS OF INCOME

                          YEAR ENDED DECEMBER 31, 1997

                      (IN THOUSANDS, EXCEPT PER SHARE DATA)

<TABLE>
<CAPTION>
                                                                           HISTORICAL
                                                            HISTORICAL      RESEARCH       PRO FORMA          PRO FORMA
                                                            INVITROGEN      GENETICS      ADJUSTMENTS          COMBINED
                                                             ---------      ---------       ----------         ---------
<S>                                                         <C>            <C>            <C>                 <C>
Revenues.................................................     $ 41,182       $ 14,331        $   (179) (2)      $ 55,334
Cost of Revenues.........................................       15,958          6,840             (85) (2)        22,713
                                                             ---------      ---------       ----------         ---------
   Gross margin..........................................       25,224          7,491             (94)            32,621
Operating Expenses:
  Sales and marketing....................................        8,305          1,630               -              9,935
  General and administrative.............................        7,312          2,252               -              9,564
  Research and development...............................        5,918          1,721             (94) (2)         7,545
                                                             ---------      ---------       ----------         ---------
     Total operating expenses............................       21,535          5,603             (94)            27,044
                                                             ---------      ---------       ----------         ---------
       Income from operations............................        3,689          1,888               -              5,577
                                                             ---------      ---------       ----------         ---------
Other Income (Expense):
  Gain (loss) on foreign currency transactions...........          145              -               -                145
  Interest and other expense.............................         (242)          (456)              -               (698)
  Interest and other income..............................          214             25               -                239
                                                             ---------      ---------       ----------         ---------
                                                                   117           (431)              -               (314)
                                                             ---------      ---------       ----------         ---------
Income before provision for income taxes.................        3,806          1,457               -              5,263
Provision for income taxes...............................        1,371            475               -              1,846
                                                             ---------      ---------       ----------         ---------
  Net income.............................................        2,435            982               -              3,417

Less:  Preferred stock dividends.........................         (475)             -               -               (475)
      Accretion of non-voting redeemable common stock....         (175)             -               -               (175)
      Adjustment to beneficial conversion feature related
        to convertible preferred stock...................      (15,000)            -               -            (15,000)
                                                             ---------      ---------       ----------         ---------
       Income available to common stockholders...........     $(13,215)     $    982        $      -           $ (12,233)
                                                             =========      =========       ==========         =========
Earnings per share:
  Basic..................................................     $  (1.15)      $  19.64                           $  (0.83)
                                                             =========      =========                          =========
  Diluted................................................     $  (1.15)      $  19.64                           $  (0.83)
                                                             =========      =========                          =========
Weighted average shares used in per share calculation:
  Basic..................................................       11,461             50                             14,661   (3)
  Diluted................................................       11,461             50                             14,661   (3)
</TABLE>

         See Notes to Unaudited Pro Forma Combined Financial Statements.


<PAGE>



                  INVITROGEN CORPORATION AND RESEARCH GENETICS
           NOTES TO UNAUDITED PRO FORMA COMBINED FINANCIAL STATEMENTS

1.       BASIS OF PRESENTATION

The Merger will be accounted for as a pooling of interests. Under this method of
accounting the unaudited pro forma combined statements of income combine the
historical statements of income for Invitrogen for the three years ended
December 31, 1999 with the historical statements of income for Research Genetics
for the same periods. All unaudited pro forma combined income statements assume
consummation of the Merger on January 1, 1997. The unaudited pro forma combined
balance sheet combines the historical balance sheets of Invitrogen and Research
Genetics at December 31, 1999 and assumes consummation of the Merger on December
31, 1999.

2.   INTERCOMPANY TRANSACTIONS

All significant intercompany sales and balances have been eliminated in the
combination.

3.   MERGER TRANSACTION

The unaudited pro forma combined financial statements reflects the issuance of
3.2 million shares of Invitrogen common stock for all of the outstanding common
stock for Research Genetics at an exchange ratio of 64.

4.   MERGER COSTS

Costs incurred as a result of the Merger are expected to be $6.1 million and are
subject to change. These costs were expensed in February 2000 after the Merger
was completed. Included in these costs are $2.2 million in fees paid by research
Genetics' principal shareholder. These fees are treated as capital contribution
to the company. The unaudited pro forma combined statements of income exclude
expenses related to the Merger as they are nonrecurring in nature.


<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FNIANCIAL INFORMATION EXTRACTED FROM INVITROGEN
CORPORATION'S NEWS RELEASE DATED FEBRUARY 17, 2000 ATTACHED HERETO AS AN EXHIBIT
AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000

<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-START>                             JAN-01-1999
<PERIOD-END>                               DEC-31-1999
<CASH>                                         102,220
<SECURITIES>                                         0
<RECEIVABLES>                                    7,462
<ALLOWANCES>                                       435
<INVENTORY>                                      5,344
<CURRENT-ASSETS>                               123,595
<PP&E>                                          16,143
<DEPRECIATION>                                   7,743
<TOTAL-ASSETS>                                 135,992
<CURRENT-LIABILITIES>                            9,649
<BONDS>                                            721
                                0
                                          0
<COMMON>                                           191
<OTHER-SE>                                     125,431
<TOTAL-LIABILITY-AND-EQUITY>                   135,992
<SALES>                                         66,595
<TOTAL-REVENUES>                                68,312
<CGS>                                           23,018
<TOTAL-COSTS>                                   23,018
<OTHER-EXPENSES>                                36,815
<LOSS-PROVISION>                                   169
<INTEREST-EXPENSE>                                 244
<INCOME-PRETAX>                                 10,199
<INCOME-TAX>                                     3,534
<INCOME-CONTINUING>                              6,665
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                    56,665
<EPS-BASIC>                                       0.47
<EPS-DILUTED>                                     0.40


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM RESEARCH
GENETICS' FINANCIAL STATEMENTS AS OF DECEMBER 31, 1999 AND 1998 AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000

<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-START>                             JAN-01-1999
<PERIOD-END>                               DEC-31-1999
<CASH>                                               1
<SECURITIES>                                         0
<RECEIVABLES>                                    4,709
<ALLOWANCES>                                       400
<INVENTORY>                                      2,146
<CURRENT-ASSETS>                                 7,191
<PP&E>                                          18,865
<DEPRECIATION>                                   5,955
<TOTAL-ASSETS>                                  21,132
<CURRENT-LIABILITIES>                            8,588
<BONDS>                                          6,535
                                0
                                          0
<COMMON>                                             5
<OTHER-SE>                                       5,565
<TOTAL-LIABILITY-AND-EQUITY>                    21,132
<SALES>                                         24,573
<TOTAL-REVENUES>                                24,581
<CGS>                                            9,674
<TOTAL-COSTS>                                    9,674
<OTHER-EXPENSES>                                10,820
<LOSS-PROVISION>                                    50
<INTEREST-EXPENSE>                                 447
<INCOME-PRETAX>                                  3,640
<INCOME-TAX>                                     1,245
<INCOME-CONTINUING>                              2,395
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     2,395
<EPS-BASIC>                                      47.90
<EPS-DILUTED>                                    47.90


</TABLE>


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