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<PAGE>
EXHIBTI 16.1
September 15, 2000
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549
Commissioners:
We have read the statements made by drkoop.com, Inc., which we understand will
be filed with the Commission, pursuant to Item 4 of Form 8-K, as part of the
Company's Form 8-K report dated September 15, 2000. We agree with the statements
concerning our Firm in such Form 8-K.
Very truly yours,
PricewaterhouseCoopers LLP
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