XOMA LTD
10-K/A, 1996-05-23
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                 AMENDMENT NO. 2
                                       ON
                                   FORM 10-K/A

[X]   ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE
      ACT OF 1934 [FEE REQUIRED]

                                       OR

[ ]   TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES
      EXCHANGE ACT OF 1934 [NO FEE REQUIRED]

FOR THE FISCAL YEAR ENDED
DECEMBER 31, 1995                                    COMMISSION FILE NO. 0-14710


                                XOMA CORPORATION
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

    DELAWARE                                              94-2756657
(STATE OF INCORPORATION)                    (I.R.S. EMPLOYER IDENTIFICATION NO.)

    2910 SEVENTH STREET,
    BERKELEY, CALIFORNIA                                   94710
    (ADDRESS OF PRINCIPAL                                (ZIP CODE)
    EXECUTIVE OFFICES)

               REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE:
                                 (510) 644-1170

           SECURITIES REGISTERED PURSUANT TO SECTION 12(B) OF THE ACT:
                                      NONE

           SECURITIES REGISTERED PURSUANT TO SECTION 12(G) OF THE ACT:
                         COMMON STOCK, $.0005 PAR VALUE
                         PREFERRED STOCK PURCHASE RIGHTS

         Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days. Yes X No

         Indicate by check mark if disclosure of delinquent filers pursuant to
Item 405 of Regulation S-K is not contained herein, and will not be contained,
to the best of registrant's knowledge, in definitive proxy or information
statements incorporated by reference in Part III of this Form 10-K or any
amendment to this Form 10-K.  [X]

         The aggregate market value of voting stock held by nonaffiliates of the
registrant, as of April 24, 1996:  $171,197,551.

         Number of shares of Common Stock outstanding as of April 24, 1996:
31,581,420.

                       DOCUMENTS INCORPORATED BY REFERENCE

         Portions of the Company's Proxy Statement for the Company's 1996 Annual
Meeting of Stockholders are incorporated by reference into Part III of this
Report.



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                                     PART IV


ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

         (a)      List of documents filed as part of this Report.

                  (1)      Financial Statements:

                           All financial statements of the registrant referred
                           to in Item 8 of this Report on Form 10-K.

                  (2)      Financial Statement Schedules:

                           All financial statements schedules have been omitted
                           since the required information is included in the
                           financial statements or the notes thereto, or is not
                           applicable or required.

                  (3)      Exhibits:

                           See "Index to Exhibits."

         (b)      Reports on Form 8-K.

                  None.


                                       -2-

<PAGE>
<PAGE>



                                   SIGNATURES


            Pursuant to the requirements of Section 13 or 15(d) of the
Securities Exchange Act of 1934, the registrant has duly caused this report to
be signed on its behalf by the undersigned, thereunto duly authorized, on this
23rd day of May, 1996.


                                            XOMA CORPORATION


                                        By  /s/ JOHN L. CASTELLO
                                            ---------------------------------
                                            John L. Castello,
                                            Chairman of the Board, President
                                            and Chief Executive Officer


            Pursuant to the requirements of the Securities Exchange Act of 1934,
this report has been signed below by the following persons on behalf of the
registrant and in the capacities and on the dates indicated.


SIGNATURE                              TITLE                          DATE
- - ---------                              -----                          ----

/s/ JOHN L. CASTELLO       Chairman of the Board, President        May 23, 1996
- - -----------------------    and Chief Executive Officer
(John L. Castello)         (Principal Executive Officer)


/s/ PATRICK J. SCANNON     Chief Scientific and                    May 23, 1996
- - -----------------------    Medical Officer and Director
(Patrick J. Scannon)                    


/s/ PETER B. DAVIS         Vice President, Finance                 May 23, 1996
- - -----------------------    and Chief Financial Officer
(Peter B. Davis)           (Principal Financial and
                           Accounting Officer)


                                       -3-

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SIGNATURE                              TITLE                          DATE
- - ---------                              -----                          ----

/s/ JAMES G. ANDRESS          Director                             May 23, 1996
- - --------------------------
(James G. Andress)



/s/ WILLIAM K. BOWES, JR.     Director                             May 23, 1996
- - --------------------------
(William K. Bowes, Jr.)



/s/ ARTHUR KORNBERG           Director                             May 23, 1996
- - --------------------------
(Arthur Kornberg)



/s/ STEVEN C. MENDELL         Director                             May 23, 1996
- - --------------------------
(Steven C. Mendell)



/s/ W. DENMAN VAN NESS        Director                             May 23, 1996
- - --------------------------
(W. Denman Van Ness)



/s/ GARY WILCOX               Director                             May 23, 1996
- - --------------------------
(Gary Wilcox)


                                       -4-

<PAGE>
<PAGE>



                                INDEX TO EXHIBITS


EXHIBIT
NUMBER
- - -------

 3.1          Restated Certificate of Incorporation, as amended.12

 3.2          Amended and Restated Bylaws.12

 3.3          Stockholder Rights Agreement dated October 27, 1993
              between the Company and First Interstate Bank of
              California, as Rights Agent.13

 3.4          Certificate of Designation of Preferences and
              Rights of Convertible Preferred Stock, Series C
              of the Company.18

 4.1          Form of 4% Convertible Subordinated Debenture due
              November __, 1998 and form of 4% Convertible
              Subordinated Debenture due November 30, 1998,
              Series A.18

10.1          Form of Stock Option Agreement
              for 1981 Stock Option Plan.15

10.2          Form of Stock Option Agreement for
              Restricted Stock Plan.15

10.3          Warrant Agreement dated as of October 11,
              1985 between the Company and Equitec Leasing
              Company.1

10.4          License Agreement dated July 5, 1983 between
              the Company and ICRF Patent Limited.1

10.5          License Agreement dated October 26, 1984
              between the Company and Carlton Medical
              Products Limited.1

10.6          License Agreement dated February 3, 1986
              between the Company and the Kallestad
              Laboratories Division of Erbamont, Inc.
              (with certain confidential information
              deleted.)1

10.7          Restricted Stock Plan as amended and restated
              and further amended.7

10.8          Restricted Stock Purchase Agreement.2

10.9          License Agreement dated September 3, 1986
              between the Company and the Regents of the
              University of California (with certain
              confidential information deleted).2

10.10         Research, Development and Option Agreement,
              License Agreement, Supply Agreement, and
              Security Agreement all dated as of June 9,
              1987 between the Company and Pfizer,
              Inc. (with certain confidential
              information deleted).3

10.11         Manufacturing Agreement dated as of January
              1, 1991 between the Company and Pfizer, Inc.9



                                       -5-

<PAGE>
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EXHIBIT
NUMBER
- - -------

10.12         Lease of premises at 890 Heinz Street,
              Berkeley, California dated as of July 22,
              1987.4

10.13         Lease of premises at Building E at Aquatic Park Center, Berkeley,
              California dated as of July 22, 1987 and amendment thereto dated
              as of April 21, 1988.4

10.14         Lease of premises at Building C at Aquatic Park Center, Berkeley,
              California dated as of July 22, 1987 and amendment thereto dated
              as of August 26, 1987.4

10.15         Letter of Agreement regarding CPI adjustment dates for leases of
              premises at Buildings C, E and F at Aquatic Park Center, Berkeley,
              California dated as of July 22, 1987.4

10.16         Form of indemnification agreement for
              officers.9

10.17         Form of indemnification agreement for
              employee directors.9

10.18         Form of indemnification agreement for
              non-employee directors.9

10.19         XOMA Corporation 1981 Stock Option Plan
              as amended and restated and further
              amended.7

10.20         Lease of premises at 2910 Seventh Street,
              Berkeley, California dated March 25, 1992.15

10.21         Master Equipment Lease Agreement between
              Equitable Life Leasing Corporation and
              the Company.6

10.22         Supply Agreement effective February 27,
              1989 between the Company and Charles River
              Biotechnical Services, Inc. (with certain
              confidential information deleted).6

10.23         Amendment Agreement dated as of October
              17, 1991 between the Company and Charles
              River Laboratories, Inc. (with certain
              confidential information deleted).9

10.24         License Agreement dated as of August 31,
              1988 between the Company and Sanofi (with
              certain confidential information
              deleted).5

10.25         1985 Non-Qualified Stock Option Plan and
              form of Stock Option Agreement.8

10.26         Lease dated June 22, 1992, between the
              Company and Richard B. Gomez,
              Josephine L. Gomez, TTEE-U/A/D, 10,31-90,
              FBO Gomez Family Trust.15



                                       -6-

<PAGE>
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EXHIBIT
NUMBER
- - -------

10.27         Lease dated October 2, 1992, between the
              Company and Virginia Merritt, as Trustee
              of the Bowman Merritt and Virginia Merritt
              Trust.15

10.28         [Omitted]

10.29         [Omitted]

10.30         Research and License Agreement dated August 6, 1990 between the
              Company and New York University (with certain confidential
              information deleted).9

10.31         First Amendment to Agreement dated November 6, 1992 between the
              Company and New York University (with certain confidential
              information deleted).15

10.32         [Omitted]

10.33         License Agreement dated June 11, 1991
              between the Company and Sterling Drug Inc.
              (with certain confidential information deleted).9

10.34         Employment Agreement dated April 29, 1992
              between the Company and John L. Castello.15

10.35         Employment Agreement dated April 29, 1992
              between the Company and Steven C. Mendell15

10.36         Stipulation and Agreement of Settlement,
              Compromise and Dismissal dated May 10, 1992.10

10.37         Settlement Agreement for Litigation with
              Centocor dated July 28, 1992 (with certain
              confidential information deleted).11

10.38         Securities Purchase Agreement dated November 19,
              1993 among the Company, Ortelius and GDK.14

10.39         Subscription Agreement dated November 21, 1993
              between the Company and Shipley Raidy Capitol
              Corporation.16

10.40         Letter Agreement dated July 14, 1993 between the
              Company and Pfizer, Inc. (with certain confidential
              information deleted).16

10.41         Cross License Agreement dated December 15, 1993 between Research
              Development Foundation and the Company (with certain confidential
              information deleted).16

10.42         Cross License Agreement dated December 15, 1993 between the
              Company and Research Development Foundation (with certain
              confidential information deleted).16

10.43         Management Incentive Compensation Plan.16



                                       -7-

<PAGE>
<PAGE>

EXHIBIT
NUMBER
- - -------

10.44         Employment Agreement dated March 29, 1993 between
              the Company and Patrick J. Scannon, M.D., Ph.D.16

10.45         [Omitted]

10.46         Technology Acquisition Agreement dated
              June 3, 1994 between Connective Therapeutics,
              Inc. and the Company (with certain confidential
              information deleted).17

10.47         Employment Agreement dated April 1, 1994 between
              the Company and Peter B. Davis.17

10.48         Letter Agreement dated November 7, 1995 between the
              Company and Pfizer, Inc.  (Certain confidential
              information has been omitted from this exhibit.  The
              symbol "XXXX" indicates the location in the text of
              the exhibit of the confidential information so omitted.
              Such information has been filed separately with the
              Securities and Exchange Commission in connection with
              a request for confidential treatment.)18

10.49         Amendment No. 1 to License Agreement dated
              March 23, 1995 between the Company and Burroughs
              Wellcome Co.  (Certain confidential information
              has been omitted from this exhibit.  The symbol "XXXX"
              indicates the location in the text of the exhibit of
              the confidential information so omitted.  Such
              information has been filed separately with the
              Securities and Exchange Commission in connection
              with a request for confidential treatment.)18

10.50         Form of Offshore Subscription Agreement relating to
              the Company's Convertible Preferred Stock, Series C.18

10.51         Form of Offshore Securities Subscription Agreement
              relating to the Company's 4% Convertible Subordinated
              Debentures due 1998.18

10.52         Form of Letter Agreement relating to the Company's
              4% Convertible Subordinated Debentures due
              November 30, 1998, Series A.18

23.1          Consent of Independent Public Accountants.18

27.1          Financial Data Schedule.18

- - -------------------------

1     Incorporated by reference to the Company's initial Registration Statement
      on Form S-1 (File No. 33-4793).

2     Incorporated by reference to the Company's Registration Statement on Form
      S-1 (File No. 33-12832).

3     Incorporated by reference to the Company's report on Form 10-Q for the
      quarter ended June 30, 1987 (File No. 0-14710).

4     Incorporated by reference to the Company's report on Form 10-K for the
      year ended December 31, 1987 (File No. 0-14710).

5     Incorporated by reference to the Company's report on Form 10-Q for the
      quarter ended September 30, 1988 (File No.0-14710).

                                       -8-

<PAGE>
<PAGE>



6     Incorporated by reference to the Company's Registration Statement on Form
      S-1 (File No. 33-27319).

7     Incorporated by reference to the Company's Registration Statement on Form
      S-8 (File No. 33-39155).

8     Incorporated by reference to Ingene Registration Statement on Form S-1
      (File No. 33-5150).

9     Incorporated by reference to the Company's Annual Report on Form 10-K for
      the fiscal year ended December 31, 1991 (File No. 0-14710).

10    Incorporated by reference to the Company's Current Report on Form 8-K
      dated May 28, 1992.

11    Incorporated by reference to the Company's Current Report on Form 8-K
      dated September 18, 1992, as amended.

12    Incorporated by reference to the Company's Registration Statement on Form
      S-3 (File No. 33-74982).

13    Incorporated by reference to the Company's Current Report on Form 8-K
      dated October 27, 1993.

14    Incorporated by reference to the Company's Current Report on Form 8-K
      dated December 21, 1993.

15    Incorporated by reference to the Company's Annual Report on Form 10-K for
      the fiscal year ended December 31, 1992 (File No. 0-14710).

16    Incorporated by reference to the Company's Annual Report on Form 10-K for
      the fiscal year ended December 31, 1993 (File No. 0-14710).

17    Incorporated by reference to the Company's Annual Report on Form 10-K for
      the fiscal year ended December 31, 1994 (File No. 0-14710).

18    Previously filed.


                                       -9-


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