EMPYREAN BIOSCIENCE INC
S-4/A, EX-99.1, 2000-11-21
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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                                                                    Exhibit 99.1

                            EMPYREAN BIOSCIENCE, INC.
                            23800 COMMERCE PARK ROAD
                                     SUITE A
                              CLEVELAND, OHIO 44122

The undersigned hereby appoints Richard C. Adamany and Bennett C. Rubin and each
of them, proxies, with power of substitution and revocation,  acting unanimously
and  voting or if only one is  present  and  voting  then that one,  to vote the
shares of stock of EMPYREAN  BIOSCIENCE,  INC. which the undersigned is entitled
to vote, at the annual meeting of  stockholders  to be held at the above address
on  ___________,  2001  at  _____________,  eastern  standard  time,  and at any
adjournment or adjournments  thereof,  with all the powers the undersigned would
possess if present:

                 For all nominees            WITHHOLD
              listed at right (except  authority to vote for
                 as marked to the       all nominees listed
                  contrary below)              below

I. ELECTION OF         [ ]                      [ ]          NOMINEES:
   DIRECTORS:                                                Richard C. Adamany
                                                             Lawrence D. Bain
INSTRUCTION: TO WITHHOLD AUTHORITY TO                        Robert G.J. Burg II
VOTE FOR ANY INDIVIDUAL NOMINEE, STRIKE                      Michael Cicak
A LINE THROUGH THAT NOMINEE'S NAME AT                        Andrew J. Fishleder
RIGHT.                                                       Bennett S. Rubin

                                                     FOR     AGAINST     ABSTAIN
2.   APPROVAL OF MERGER AGREEMENT                    [ ]       [ ]         [ ]
     BETWEEN EMPYREAN DELAWARE AND
     EMPYREAN WYOMING

                                                     FOR     AGAINST     ABSTAIN
3.   APPROVAL OF AMENDMENT TO 1998                   [ ]       [ ]         [ ]
     STOCK PLAN

4.   IN THEIR  DISCRETION,  THE  PROXIES ARE  AUTHORIZED  TO VOTE UPON ALL OTHER
     MATTERS THAT PROPERLY MAY BE PRESENTED AT THE MEETING.
<PAGE>
THIS  PROXY IS  SOLICITED  ON  BEHALF  OF THE  BOARD OF  DIRECTORS  OF  EMPYREAN
BIOSCIENCE,  INC. AND WILL BE VOTED FOR THE ELECTION OF DIRECTORS  UNLESS MARKED
TO WITHHOLD  AUTHORITY  AND WILL BE VOTED IN ACCORDANCE  WITH ANY  SPECIFICATION
INDICATED  HEREON;  IN THE ABSENCE OF A SPECIFICATION  AS TO ANY PROPOSAL,  THIS
PROXY WILL BE VOTED FOR SUCH PROPOSAL.

PLEASE SIGN AND DATE AND RETURN  PROMPTLY IN THE ENCLOSED  ENVELOPE.  NO POSTAGE
NEED BE AFFIXED IF MAILED IN THE UNITED STATES.

The undersigned  hereby revokes proxy or proxies  heretofore  given to vote such
shares at said meeting or at any adjournment thereof.

Signature of Stockholder: _____________________________ Date:_____________

FIRST CLASS MAIL  IMPORTANT:  PLEASE  SIGN AND RETURN  PROMPTLY  PROXY  MATERIAL
ENCLOSED. (Please sign exactly as name appears on this proxy, indicating,  where
proper, official position or representative capacity).


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