EMPYREAN BIOSCIENCE INC
S-4/A, EX-3.1.A, 2000-09-05
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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                          CERTIFICATE OF INCORPORATION

                                       OF

                            EMPYREAN BIOSCIENCE, INC.


     FIRST: The name of the Corporation is Empyrean Bioscience, Inc.

     SECOND:  The address of its  registered  office in the State of Delaware is
No. 1209 Orange  Street,  in the City of Wilmington,  County of New Castle.  The
name of its registered agent at such address is The Corporation Trust Company.

     THIRD:  The nature of the  business or purposes to be conducted or promoted
is:  To engage in any  lawful  act or  activity  for which  corporations  may be
organized under the General Corporation Law of Delaware.

     FOURTH: The number of shares for all classes of stock which the Corporation
is authorized to have outstanding is One Hundred Million  (100,000,000),  Ninety
Million  (90,000,000)  of which shall be designated as Common  Shares,  having a
$.0001 par value,  and Ten Million  (10,000,000) of which shall be designated as
Preferred Stock.

     FIFTH: Unless otherwise specified in this Certificate of Incorporation,  no
holder of shares of stock of the Corporation  shall have any preemptive right or
other right to receive any securities of the Corporation.

     SIXTH:  The  Board of  Directors  is  authorized,  subject  to  limitations
prescribed by law and the provisions of the Article  FOURTH,  to provide for the
issuance of the shares of Preferred Stock in series, and by filing a certificate
pursuant to the applicable law of the State of Delaware,  to establish from time
to time the number of shares to be included in each such series,  and to fix the
designation,  powers,  preferences  and rights of the shares of each such series
and the qualifications, limitations or restrictions thereof.

     The authority of the Board with respect to each series shall  include,  but
not be limited to, determination of the following:

     (a)  The number of shares  constituting  that  series  and the  distinctive
          designation of that series;

     (b)  The  dividend  rate on the shares of that  series,  whether  dividends
          shall be  cumulative,  and, if so,  from which date or dates,  and the
          relative rights of priority, if any, of payment of dividends on shares
          of that series;

     (c)  Whether  that  series  shall have  voting  rights,  in addition to the
          voting  rights  provided by law,  and, if so, the terms of such voting
          rights;

     (d)  Whether that series shall have conversion privileges,  and, if so, the
          terms and  conditions  of such  conversion,  including  provision  for
          adjustment  of the  conversion  rate in such  events  as the  Board of
          Directors shall determine;
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     (e)  Whether or not the shares of that series shall be redeemable,  and, if
          so, the terms and conditions of such redemption, including the date or
          date upon or after which they shall be redeemable,  and the amount per
          share  payable  in case of  redemption,  which  amount  may vary under
          different conditions and at different redemption dates;

     (f)  Whether that series shall have a sinking  fund for the  redemption  or
          purchase of shares of that series, and, if so, the terms and amount of
          such sinking fund;

     (g)  The rights of the shares of that series in the event of  voluntary  or
          involuntary liquidation, dissolution or winding up of the corporation,
          and the relative  rights of priority,  if any, of payment of shares of
          that series;

     (h)  Any other relative rights, preferences and limitations of that series.

     Dividends  on  outstanding  shares  of  Preferred  Stock  shall  be paid or
declared  and set  apart  for  payment  before  any  dividends  shall be paid or
declared and set apart for payment on the common shares with respect to the same
dividend period.

     If upon any voluntary or involuntary liquidation, dissolution or winding up
of the  corporation,  the assets available for distribution to holders of shares
of Preferred  Stock of all series shall be  insufficient to pay such holders the
full preferential  amount to which they are entitled,  then such assets shall be
distributed  ratably  among the  shares  of all  series  of  Preferred  Stock in
accordance with the respective preferential amounts (including unpaid cumulative
dividends, if any) payable with respect thereto.

     SEVENTH:  The name of the  Incorporator is ACFB  Incorporated.  The mailing
address is 2300 BP Tower, 200 Public Square, Cleveland, Ohio 44114.

     EIGHTH: The Corporation is to have perpetual existence.

     NINTH:  Except as  otherwise  fixed by or  pursuant  to the  provisions  of
Article VI hereof  relating  to the rights of the holders of any class or series
of stock  having a  preference  over the Common  Stock as to  dividends  or upon
liquidation,  the number of the directors of the Corporation shall be fixed from
time to time by this  Certificate of  Incorporation or pursuant to the Bylaws of
the  Corporation.  The  Directors on the Board of Directors  shall be classified
with respect to the time for which they shall  severally hold office by dividing
them into three classes. The number of directors of the Corporation shall not be
less than one (1) nor more than  fifteen  (15).  The initial  Board of Directors
shall  consist of six (6)  members.  If the total  number of directors is evenly
divisible by three,  then each class shall have one-third of the total number of
directors.  If the total number of  directors is not evenly  divisible by three,
the Board of Directors shall by resolution  determine the number of directors in
each class, which shall be, as nearly as possible,  the same for each class. All
directors  of the  Corporation  shall hold  office  until their  resignation  or
removal or until their successors are duly elected and qualified.  The directors
of the first  class  shall hold  office  until the first  annual  meeting of the
stockholders  to be held after the date upon which such director was elected and
until their  successors  are duly elected and  qualified;  the  directors of the
second  class  shall  hold  office  until  the  second  annual  meeting  of  the
stockholders  to be held after  such date and until  their  successors  are duly
elected and  qualified;  and the  directors of the third class shall hold office
until the third annual  meeting of  stockholders  to be held after such date and
until their successors are duly elected and qualified. At each annual meeting of
stockholders  following the first annual meeting, the successors to the class of
directors  whose  terms  shall  expire in that year shall be  elected,  and said

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successors  shall  hold  office  until the third  following  annual  meeting  of
stockholders  and until  the  election  and  qualification  of their  respective
successors.  If successors to the class of directors  whose term shall expire at
the annual  meeting of  stockholders  are not elected at such meeting or if such
meeting  is  not  held,  directors  may  be  elected  at a  special  meeting  of
stockholders as successors to that class of directors.

     Advance notice of nominations  for the election of directors shall be given
in the manner and to the extent provided in the Bylaws of the Corporation.

     Except as otherwise  provided for or fixed by or pursuant to the provisions
of  Article  VI hereof  relating  to the  rights of the  holders of any class or
series of stock having  preference over the Common Stock as to dividends or upon
liquidation,  newly  created  directorships  resulting  from any increase in the
number of directors may be filled by the Board of Directors and any vacancies of
the Board of Directors resulting from death, resignation, removal or other cause
shall  only be filled by the  affirmative  vote of a majority  of the  remaining
directors  then in  office,  even  though  less  than a quorum  of the  Board of
Directors, or by a sole remaining director, and in accordance with the Bylaws of
the Corporation.  Any director elected in accordance with the preceding sentence
of this  paragraph  shall hold office for the  remainder of the full term of the
director  and until  such  director's  successor  shall  have been  elected  and
qualified.

     Any director or the entire Board of Directors may be removed only for cause
and only by the vote of the  holders  of a  majority  of the  securities  of the
Corporation  then entitled to vote at an election of directors.  For purposes of
this Certificate of  Incorporation,  "cause" shall mean gross neglect or willful
misconduct in the performance of the duties as a director.

     TENTH:  In  furtherance  and not in limitation  of the powers  conferred by
statute, the board of directors is expressly authorized:

          To make, alter or repeal the bylaws of the Corporation.

          To  authorize  and cause to be executed  mortgages  and liens upon the
     real property of the Corporation.

          To set apart out of any of the funds of the Corporation  available for
     dividends a reserve or reserves  for any proper  purpose and to abolish any
     such reserve in the manner in which it was created.

          By a majority of the whole board, to designate one or more committees,
     each  committee  to  consist  of  one  or  more  of  the  directors  of the
     Corporation.

          When and as authorized  by the  stockholders  in accordance  with this
     Certificate of  Incorporation  and applicable  statutes,  to sell, lease or
     exchange  all or  substantially  all  of the  property  and  assets  of the
     Corporation, including its goodwill and its corporate franchises, upon such

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<PAGE>
     terms and  conditions  and for such  consideration  (which may consist,  in
     whole or in part,  of money or  property,  including  shares  of stock  in,
     and/or other  securities of, any other  corporation or corporations) as the
     Corporation's  Board of Directors  shall deem  appropriate  and in the best
     interests of the Corporation.

     ELEVENTH:  Meetings of stockholders may be held within or without the State
of Delaware, as the bylaws may provide. The books of the Corporation may be kept
(subject  to any  provision  contained  in the  statutes)  outside  the State of
Delaware at such place or places as may be  designated  from time to time by the
board of directors or in the bylaws of the  Corporation.  Elections of directors
need not be by written  ballot  unless the  bylaws of the  Corporation  shall so
provide.

     TWELFTH : Nominations of persons for election to the Board of Directors may
be made at an annual meeting of  stockholders or special meeting of stockholders
called by the Board of Directors for the purpose of electing directors (i) by or
at the  direction  of the Board of Directors  or (ii) by an  stockholder  of the
Corporation  entitled to vote for the  election of directors at such meeting who
complies  with the notice of  procedures  set forth in this  Article  XII.  Such
nominations,  other  than  those  made by or at the  direction  of the  Board of
Directors,  shall be made  pursuant to timely notice in writing to the Secretary
of the Corporation. To be timely, a stockholder's notice must be delivered to or
mailed or received at the principal  executive  offices of the  Corporation  not
less  than 60 days nor more  than 90 days  prior  to the  scheduled  date of the
meeting, regardless of any postponement, deferral or adjournment of that meeting
to a later date; provided,  however,  that if less than 70 days' notice or prior
public  disclosure of the date of the meeting is given or made to  stockholders,
notice by the  stockholder  to be timely must be so  delivered  or received  not
later than the close of  business of the 10th day  following  the earlier or (i)
the date on which such  notice of the date of the meeting was mailed or (ii) the
day on which such public disclosure was made.

     A  stockholder's  notice  to the  Secretary  shall set forth (i) as to each
person whom the stockholder proposes to nominate for election or reelection as a
director  (a) the name,  age,  business  address and  residence  address of such
person, (b) the principal occupation or employment of such person, (c) the class
and  number of shares of the  Corporation  that are  beneficially  owned by such
person on the date of such  stockholder's  notice and (d) any other  information
relating to such person that is required to be  disclosed  in  solicitations  of
proxies for  election  of  directors,  or is  otherwise  required,  in each case
pursuant to  Regulation  14A under the  Securities  Exchange Act of 1934, or any
successor statute thereto (including,  without limitation, such person's written
consent to being named in the proxy  statement  as a nominee and to serving as a
director if elected);  (ii) as to the stockholder giving notice (a) the name and
address,  as  such  information  appears  on the  Corporation's  books,  of such
stockholder  and  any  other  stockholders  known  by  such  stockholder  to  be
supporting  such  nominee(s),  (b)  the  class  and  number  of  shares  of  the
Corporation  that are  beneficially  owned by such  stockholder  and each  other
stockholder  known by such  stockholder to be supporting  such nominee(s) on the
date of such stockholder  notice, (c) a representation that the stockholder is a
holder of record of stock of the  Corporation  entitled to vote at such  meeting
and  intends  to appear in person or by proxy at the  meeting  to  nominate  the
person or  persons  specified  in the  notice;  and (iii) a  description  of all
arrangements  or  understandings  between the  stockholder  and each nominee and
other person or persons  (naming  such person or persons)  pursuant to which the
nomination or nominations are to be made by the stockholder.

                                       4
<PAGE>
     Subject to the rights,  if any,  of the holders of any series of  Preferred
Stock then  outstanding,  no person shall be eligible for election as a director
of the Corporation  unless nominated in accordance with the procedures set forth
in this Article XII. The chairman of the meeting  shall,  if the facts  warrant,
determine  and  declare  to the  meeting  that a  nomination  was  not  made  in
accordance  with the procedures  prescribed by this Article XII and if he should
so determine,  he shall so declare to the meeting and the  defective  nomination
shall be disregarded.

     THIRTEENTH: At the annual meeting of stockholders, only such business shall
be conducted,  and only such  proposals  shall be acted upon, as shall have been
properly  brought  before the annual  meeting of  stockholders  (i) by or at the
direction of the Board of Directors or (ii) by a stockholder of the  Corporation
who complies with the procedures set forth in this Article XIII. For business or
a proposal to be properly  brought before an annual meeting of stockholders by a
stockholder, the stockholder must have given timely notice thereof in writing to
the Secretary of the Corporation.  To be timely, a stockholder's  notice must be
delivered to or mailed and received at the  principal  executive  offices of the
Corporation  not less than 60 days nor more than 90 days prior to the  scheduled
date  of the  annual  meeting,  regardless  of  any  postponement,  deferral  or
adjournment  of that meeting to a later date;  provided,  however,  that if less
than 70  days'  notice  or prior  public  disclosure  of the date of the  annual
meeting is given or made to stockholders, notice by the stockholder to be timely
must be so delivered or mailed and received not later than the close of business
on the 10th day following the earlier of (i) the day on which such notice of the
date of the meeting  was mailed or (ii) the day on which such public  disclosure
was made.

     A  stockholder's  notice to the Secretary shall set forth as to each matter
the stockholder proposes to bring before an annual meeting of stockholders (i) a
description,  in 500 words or less, of the business desired to be brought before
the annual  meeting and the reasons for  conducting  such business at the annual
meeting,  (ii)  the  name  and  address,  as  such  information  appears  on the
Corporation's  books, of the  stockholder  proposing such business and any other
stockholder known by such stockholder to be supporting such proposal,  (iii) the
class and number of shares of the  Corporation  that are  beneficially  owned by
such  stockholder  and each other  stockholder  known by such  stockholder to be
supporting  such  proposal  on the  date of such  stockholder's  notice,  (iv) a
description,  in 500 words or less, of any interest of the  stockholder  in such
proposal and (v) a representation  that the stockholder is a holder of record of
stock of the  Corporation  and  intends  to  appear in person or by proxy at the
meeting to present the proposal specified in the notice.

     The chairman of the meeting  shall,  if the facts  warrant,  determine  and
declare to the meeting that the business  was not  properly  brought  before the
meeting in accordance  with the procedures  prescribed by this Article XIII, and
if he should so  determine,  he shall so  declare  to the  meeting  and any such
business  not  properly  brought  before the  meeting  shall not be  transacted.
Notwithstanding the foregoing, nothing in this Article XIII shall be interpreted
or construed to require the inclusion of information  about any such proposal in
any proxy  statement  distributed  by, at the direction of, or on behalf of, the
Board of Directors.

     FOURTEENTH:  The Corporation  reserves the right to amend, alter, change or
repeal any provision  contained in this  Certificate  of  Incorporation,  in the
manner now or hereafter  prescribed by statute,  and all rights  conferred  upon
stockholders herein are granted subject to this reservation.

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     FIFTEENTH: No director shall be personally liable to the Corporation or any
of its  stockholders  for  monetary  damages for breach of  fiduciary  duty as a
director,  except for  liability  (1) for any breach of the  director's  duty of
loyalty to the Corporation or its stockholders, (2) for acts or omissions not in
good faith or which involve  intentional  misconduct  or a knowing  violation of
law, (3) under Section 174 of the Delaware  General  Corporation Law, or (4) for
any transaction from which the director derived an improper personal benefit. If
the Delaware  General  Corporation  Law  hereafter  is amended to authorize  the
further  elimination  or  limitation  of the  liability of  directors,  then the
liability of a director of the  Corporation,  in addition to the  limitations on
personal  liability  provided  herein,  shall be limited to the  fullest  extent
permitted  by the  amended  Delaware  General  Corporation  Law.  Any  repeal or
modification of this Article shall be prospective  only, and shall not adversely
affect any limitation on the personal liability of a director of the Corporation
existing at the time of such repeal or modification.

     SIXTEENTH: A. Each person who was or is made a party to or is threatened to
be made a party to or is  involved in any action,  suit or  proceeding,  whether
civil, criminal,  administrative or investigative  (hereinafter a "proceeding"),
by reason of the fact that he or she, or a person of whom he or she is the legal
representative,  is or was a director or officer of the Corporation or is or was
serving at the request of the  Corporation as a director,  officer,  employee or
agent of another corporation or of a partnership,  joint venture, trust or other
enterprise,  including  service with respect to employee benefit plans,  whether
the basis of such  proceeding  is alleged  action in an  official  capacity as a
director, officer, employee or agent or in any other capacity while serving as a
director,  officer, employee or agent, shall be indemnified and held harmless by
the  Corporation  to the fullest  extent,  authorized  by the  Delaware  General
Corporation  Law, as the same exists or may  hereafter be amended  (but,  in the
case of any such amendment,  only to the extent that such amendment  permits the
Corporation to provide  broader  indemnification  rights than said law permitted
the  Corporation  to provide  prior to such  amendment),  against  all  expense,
liability and loss (including attorneys' fees,  judgments,  fines, ERISA, excise
taxes or  penalties  and amounts  paid or to be paid in  settlement)  reasonably
incurred  or  suffered  by  such  person  in   connection   therewith  and  such
indemnification  shall  continue as to a person who has ceased to be a director,
officer,  employee  or agent and shall inure to the benefit of his or her heirs,
executors and  administrators;  provided,  however,  that, except as provided in
subsection B of this Article,  the  Corporation  shall indemnify any such person
seeking  indemnification  in  connection  with a  proceeding  (or part  thereof)
initiated  by  such  person  only if  such  proceeding  (or  part  thereof)  was
authorized  by  the  Board  of  Directors  of  the  Corporation.  The  right  to
indemnification  conferred in this Article  shall be a contract  right and shall
include  the  right  to be paid by the  Corporation  the  expenses  incurred  in
defending  any such  proceeding in advance of its final  disposition;  provided,
however,  that if the Delaware General Corporation Law requires,  the payment of
such  expenses  incurred  by a director  or officer in his or her  capacity as a
director or officer  (and not in any other  capacity in which  service was or is
rendered  by such  person  while  a  director  or  officer,  including,  without
limitation,  service  to an  employee  benefit  plan) in  advance  of the  final
disposition of a proceeding  shall be made only upon delivery to the Corporation
of an  undertaking,  by or on behalf of such  director or officer,  to repay all
amounts so advanced if it shall  ultimately be determined  that such director or
officer is not entitled to be indemnified  under this Article or otherwise.  The

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Corporation may, by action of its Board of Directors, provide indemnification to
employees  and agents of the  Corporation  with the same scope and effect as the
foregoing indemnification of directors and officers.

     B. If a claim under subsection A of this Article is not paid in full by the
Corporation  within  thirty (30) days after a written claim has been received by
the Corporation,  the claimant may at any time thereafter bring suit against the
Corporation  to recover  the unpaid  amount of the claim and, if  successful  in
whole or in part,  the claimant shall be entitled to be paid also the expense of
prosecuting  such claim. It shall be a defense to any such action (other than an
action  brought  to  enforce a claim for  expenses  incurred  in  defending  any
proceeding in advance of its final disposition  where the required  undertaking,
if any is required,  has been tendered to the Corporation) that the claimant has
not met the  standards of conduct which make it  permissible  under the Delaware
General  Corporation  Law for the  Corporation to indemnify the claimant for the
amount  claimed,  but  the  burden  of  proving  such  defense  shall  be on the
Corporation.  Neither the  failure of the  Corporation  (including  its Board of
Directors,  independent  legal  counsel,  or its  stockholders)  to have  made a
determination  prior to the commencement of such action that  indemnification of
the  claimant  is  proper  in the  circumstances  because  he or she has met the
applicable  standard of conduct set forth in the  Delaware  General  Corporation
Law, nor an actual  determination  by the  Corporation  (including  its Board of
Directors, independent legal counsel, or its stockholders) that the claimant has
not met such applicable standard of conduct, shall be a defense to the action or
create a presumption  that the claimant has not met the  applicable  standard of
conduct.

     C. The right to  indemnification  and the payment of  expenses  incurred in
defending a  proceeding  in advance of its final  disposition  conferred in this
Article  shall not be  exclusive of any other right which any person may have or
hereafter   acquire  under  any  statute,   provision  of  this  Certificate  of
Incorporation, bylaw, agreement, vote of stockholders or disinterested directors
or otherwise.

     D. The  Corporation  may maintain  insurance,  at its  expense,  to protect
itself  and any  director,  officer,  employee  or agent of the  Corporation  or
another  corporation,  partnership,  joint  venture,  trust or other  enterprise
against any such  expense,  liability  or loss,  whether or not the  Corporation
would have the power to indemnify such person against such expense, liability or
loss under the Delaware General Corporation Law.

     E. As used in this Article,  references to "the Corporation" shall include,
in  addition  to  the  resulting  or  surviving  corporation,   any  constituent
corporation  absorbed  in a  consolidation  or  merger  which,  if its  separate
existence  had  continued,  would have had power and  authority to indemnify its
directors,  officers,  employees and agents,  so that any person who is or was a
director,  officer, employee or agent of such constituent corporation,  or is or
was  serving  at the  request of such  constituent  corporation  as a  director,
officer, employee or agent of another corporation,  partnership,  joint venture,
trust,  or  other  enterprise,  shall  stand  in the  same  position  under  the
provisions   of  this  Article  with  respect  to  the  resulting  or  surviving
corporation as he would have with respect to such constituent corporation if its
separate existence had continued.

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     F. If this Article or any portion hereof shall be invalidated on any ground
by any court of competent jurisdiction,  then the Corporation shall nevertheless
indemnify each director,  officer,  employee and agent of the  Corporation as to
expenses  (including  attorneys'  fees),  judgments,  fines and amounts  paid in
settlement  with  respect to any  action,  suit or  proceeding,  whether  civil,
criminal, administrative or investigative, including a grand jury proceeding and
an action by the Corporation,  to the fullest extent permitted by any applicable
portion of this  Article  that shall not have been  invalidated  or by any other
applicable law.

     THE UNDERSIGNED,  being the Incorporator hereinabove named, for the purpose
of forming a corporation pursuant to the General Corporation Law of the State of
Delaware, does make this certificate,  hereby declaring and certifying that this
is its act and deed and the facts herein stated are true,  and  accordingly  has
hereunto set its hand this _____ day of July, 2000.

                                       ACFB INCORPORATED
                                       Incorporator


                                       By:
                                            ------------------------------------
                                            Jill Silver, Assistant Secretary

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