SUNAMERICA STRATEGIC INVESTMENT SERIES INC
NSAR-B, 1999-12-22
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<PAGE>      PAGE  1
000 B000000 10/31/99
000 C000000 0001075318
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 SUNAMERICA STRATEGIC INVESTMENT SERIES, INC.
001 B000000 811-09169
001 C000000 2125515223
002 A000000 733 THIRD AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10017
002 D020000 3204
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 Y
007 B000000  1
007 C010100  1
007 C020100 TAX MANAGED EQUITY FUND
007 C030100 N
007 C010200  2
007 C010300  3
007 C010400  4
007 C010500  5
007 C010600  6
007 C010700  7
007 C010800  8
007 C010900  9
007 C011000 10
011 A00AA01 SUNAMERICA CAPITAL SERVICES, INC.
011 B00AA01 8-28733
011 C01AA01 NEW YORK
011 C02AA01 NY
011 C03AA01 10017
011 C04AA01 3204
012 A00AA01 SUNAMERICA FUND SERVICES, INC.
012 B00AA01 84-
012 C01AA01 NEW YORK
012 C02AA01 NY
012 C03AA01 10017
012 C04AA01 3204
013 A00AA01 PRICEWATERHOUSECOOPERS LLP
013 B01AA01 NEW YORK
013 B02AA01 NY
013 B03AA01 10036
<PAGE>      PAGE  2
014 A00AA01 ROYAL ALLIANCE ASSOCIATES
014 B00AA01 8-40218
014 A00AA02 SUNAMERICA SECURITIES, INC.
014 B00AA02 8-39428
014 A00AA03 ADVANTAGE CAPITAL CORP.
014 B00AA03 8-00000
014 A00AA04 FSC SECURITIES CORP.
014 B00AA04 8-00000
014 A00AA05 SPELMAN & CO., INC.
014 B00AA05 8-00000
014 A00AA06 SENTRA SECURITIES CORP.
014 B00AA06 8-00000
014 A00AA07 KEOGLER INVESTMENT ADVISORY, INC.
014 B00AA07 8-00000
014 A00AA08 SPECIALIZED INVESTMENTS DIVISION, INC.
014 B00AA08 8-00000
014 A00AA09 AIG EQUITY SALES CORP.
014 B00AA09 8-00000
014 A00AA10 AIG FINANCIAL SECURITIES CORP.
014 B00AA10 8-00000
014 A00AA11 AIG INTERNATIONAL SECURITIES, INC.
014 B00AA11 8-00000
015 A00AA01 STATE STREET BANK & TRUST CO.
015 B00AA01 C
015 C01AA01 NORTH QUINCY
015 C02AA01 MA
015 C03AA01 02171
015 E01AA01 X
018  00AA00 Y
019 A00AA00 Y
019 B00AA00   83
019 C00AA00 SUNAMERICA
020 A000001 JACKSON PARTNERS & ASSOCIATES, INC.
020 B000001 00-0000000
020 C000001     10
020 A000002 GOLDMAN, SACHS & CO.
020 B000002 13-5108880
020 C000002      1
020 A000003 STATE STREET BANK & TRUST CO.
020 B000003 04-1867445
020 C000003      1
020 A000004 CREDIT SUISSE FIRST BOSTON CORP.
020 B000004 13-5659485
020 C000004      1
020 A000005 INVESTMENT TECHNOLOGY GROUP, INC.
020 B000005 00-0000000
020 C000005      0
020 A000006 BEAR, STEARNS & CO., INC.
020 B000006 13-3299429
020 C000006      0
020 A000007 PRUDENTIAL SECURITIES, INC.
<PAGE>      PAGE  3
020 B000007 22-2347336
020 C000007      0
020 A000008 MORGAN STANLEY DEAN WITTER & CO.
020 B000008 13-2655998
020 C000008      0
020 A000009 CIBC WORLD MARKETS CORP.
020 B000009 13-2798343
020 C000009      0
020 A000010 INSTINET CORP.
020 B000010 13-3443395
020 C000010      0
021  000000       13
022 A000001 STATE STREET BANK & TRUST CO.
022 B000001 04-1867445
022 C000001    360125
022 D000001       588
022 A000002 INVESTMENT TECHNOLOGY GROUP, INC.
022 B000002 00-0000000
022 C000002      5634
022 D000002         0
022 A000003 CREDIT SUISSE FIRST BOSTON CORP.
022 B000003 13-5659485
022 C000003      5586
022 D000003         0
022 A000004 LOUISIANA COURT OF APPEAL THIRD CIRCUIT
022 B000004 00-0000000
022 C000004      5448
022 D000004         0
022 A000005 GOLDMAN, SACHS & CO.
022 B000005 13-5108880
022 C000005      4074
022 D000005       979
022 A000006 WEEDEN & CO. L.P.
022 B000006 13-3364318
022 C000006      4131
022 D000006         0
022 A000007 PRUDENTIAL SECURITIES, INC.
022 B000007 22-2347336
022 C000007      4106
022 D000007         0
022 A000008 SPEAR, LEEDS & KELLOGG
022 B000008 13-5515160
022 C000008      3539
022 D000008         0
022 A000009 HOENIG & CO., INC.
022 B000009 13-2656060
022 C000009      3230
022 D000009         0
022 A000010 HERZOG, HEINE, GEDULD, INC.
022 B000010 13-1955436
022 C000010      2100
<PAGE>      PAGE  4
022 D000010         4
023 C000000     403603
023 D000000       3380
026 A000000 Y
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 Y
054 A00AA00 Y
054 B00AA00 Y
054 C00AA00 Y
054 D00AA00 N
054 E00AA00 N
054 F00AA00 N
054 G00AA00 Y
054 H00AA00 Y
054 I00AA00 N
054 J00AA00 Y
054 K00AA00 N
054 L00AA00 N
054 M00AA00 Y
054 N00AA00 N
054 O00AA00 N
077 A000000 Y
077 B000000 Y
077 C000000 N
077 Q010000 Y
078  000000 N
080 A00AA00 GULF INSURANCE CO.
080 C00AA00    15000
081 A00AA00 Y
081 B00AA00  83
082 A00AA00 N
082 B00AA00        0
083 A00AA00 N
083 B00AA00        0
084 A00AA00 N
084 B00AA00        0
085 A00AA00 Y
085 B00AA00 N
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086 A020000      0
086 B010000      0
086 B020000      0
086 C010000      0
086 C020000      0
<PAGE>      PAGE  5
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
008 A000101 SUNAMERICA ASSET MANAGEMENT CORP.
008 B000101 A
008 C000101 801-19813
008 D010101 NEW YORK
008 D020101 NY
008 D030101 10017
008 D040101 3204
008 A000102 J.P. MORGAN INVESTMENT MANAGEMENT, INC.
008 B000102 S
008 C000102 801-21011
008 D010102 NEW YORK
008 D020102 NY
008 D030102 10036
024  000100 Y
025 A000101 BANKAMERICA CORP.
025 B000101 36-0947896
025 C000101 E
025 D000101    1983
025 A000102 GOLDMAN, SACHS & CO.
025 B000102 13-5108880
025 C000102 E
025 D000102     483
025 D000103       0
025 D000104       0
025 D000105       0
025 D000106       0
025 D000107       0
025 D000108       0
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028 C010100      8960
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<PAGE>      PAGE  6
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028 G040100      9067
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029  000100 Y
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030 C000100  0.00
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033  000100    661
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<PAGE>      PAGE  7
048 E010100        0
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048 K010100        0
048 K020100 0.000
049  000100 N
050  000100 N
051  000100 N
052  000100 N
053 A000100 Y
053 B000100 Y
053 C000100 N
055 A000100 N
055 B000100 N
056  000100 Y
057  000100 N
058 A000100 N
059  000100 Y
060 A000100 Y
060 B000100 Y
061  000100      500
062 A000100 N
062 B000100   0.0
062 C000100   0.0
062 D000100   0.0
062 E000100   0.0
062 F000100   0.0
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062 L000100   0.0
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062 O000100   0.0
062 P000100   0.0
062 Q000100   0.0
062 R000100   0.0
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063 B000100  0.0
066 A000100 Y
<PAGE>      PAGE  8
066 B000100 N
066 C000100 N
066 D000100 N
066 E000100 N
066 F000100 N
066 G000100 Y
067  000100 N
068 A000100 N
068 B000100 N
069  000100 N
070 A010100 Y
070 A020100 N
070 B010100 Y
070 B020100 N
070 C010100 Y
070 C020100 N
070 D010100 Y
070 D020100 N
070 E010100 Y
070 E020100 N
070 F010100 Y
070 F020100 N
070 G010100 Y
070 G020100 N
070 H010100 Y
070 H020100 N
070 I010100 N
070 I020100 N
070 J010100 Y
070 J020100 N
070 K010100 Y
070 K020100 N
070 L010100 Y
070 L020100 Y
070 M010100 Y
070 M020100 N
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070 N020100 N
070 O010100 Y
070 O020100 Y
070 P010100 N
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070 Q010100 N
070 Q020100 N
070 R010100 Y
070 R020100 N
071 A000100     77703
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<PAGE>      PAGE  9
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072 C000100      366
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072 H000100        0
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072 J000100       52
072 K000100        0
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072 M000100        4
072 N000100       89
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072 P000100        0
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072 R000100       22
072 S000100       12
072 T000100      223
072 U000100        0
072 V000100        0
072 W000100       60
072 X000100      838
072 Y000100      282
072 Z000100     -136
072AA000100        0
072BB000100      910
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072DD020100        0
072EE000100        0
073 A010100   0.0000
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074 D000100        0
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074 F000100    76579
074 G000100        0
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<PAGE>      PAGE  10
074 P000100       52
074 Q000100        0
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074 U010100     1836
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074 X000100     2885
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075 A000100        0
075 B000100    31622
076  000100     0.00
SIGNATURE   PETER SUTTON
TITLE       CONTROLLER



<TABLE> <S> <C>

<ARTICLE> 6
<CIK> 0001075318
<NAME> SUNAMERICA STRATEGIC INVESTMENT SERIES, INC.
<SERIES>
   <NUMBER> 011
   <NAME> SUNAMERICA TAX MANAGED EQUITY FUND CLASS A

<S>                             <C>
<PERIOD-TYPE>                   8-MOS
<FISCAL-YEAR-END>                          OCT-31-1999
<PERIOD-START>                             MAR-01-1999
<PERIOD-END>                               OCT-31-1999
<INVESTMENTS-AT-COST>                       75,606,117<F1>
<INVESTMENTS-AT-VALUE>                      79,640,649<F1>
<RECEIVABLES>                                1,764,612<F1>
<ASSETS-OTHER>                                  20,106<F1>
<OTHER-ITEMS-ASSETS>                            39,783<F1>
<TOTAL-ASSETS>                              81,465,150<F1>
<PAYABLE-FOR-SECURITIES>                       756,234<F1>
<SENIOR-LONG-TERM-DEBT>                              0<F1>
<OTHER-ITEMS-LIABILITIES>                      233,440<F1>
<TOTAL-LIABILITIES>                            989,674<F1>
<SENIOR-EQUITY>                                      0<F1>
<PAID-IN-CAPITAL-COMMON>                    77,352,975<F1>
<SHARES-COMMON-STOCK>                        1,835,974<F2>
<SHARES-COMMON-PRIOR>                                0<F2>
<ACCUMULATED-NII-CURRENT>                      (1,592)<F1>
<OVERDISTRIBUTION-NII>                               0<F1>
<ACCUMULATED-NET-GAINS>                      (910,439)<F1>
<OVERDISTRIBUTION-GAINS>                             0<F1>
<ACCUM-APPREC-OR-DEPREC>                     4,034,532<F1>
<NET-ASSETS>                                80,475,476<F1>
<DIVIDEND-INCOME>                              366,474<F1>
<INTEREST-INCOME>                               53,668<F1>
<OTHER-INCOME>                                       0<F1>
<EXPENSES-NET>                                 556,539<F1>
<NET-INVESTMENT-INCOME>                      (136,397)<F1>
<REALIZED-GAINS-CURRENT>                     (910,439)<F1>
<APPREC-INCREASE-CURRENT>                    4,034,532<F1>
<NET-CHANGE-FROM-OPS>                        2,987,696<F1>
<EQUALIZATION>                                       0<F1>
<DISTRIBUTIONS-OF-INCOME>                            0<F1>
<DISTRIBUTIONS-OF-GAINS>                             0<F1>
<DISTRIBUTIONS-OTHER>                                0<F1>
<NUMBER-OF-SHARES-SOLD>                      3,854,550<F2>
<NUMBER-OF-SHARES-REDEEMED>                  2,026,576<F2>
<SHARES-REINVESTED>                                  0<F2>
<NET-CHANGE-IN-ASSETS>                      80,375,476<F1>
<ACCUMULATED-NII-PRIOR>                              0<F1>
<ACCUMULATED-GAINS-PRIOR>                            0<F1>
<OVERDISTRIB-NII-PRIOR>                              0<F1>
<OVERDIST-NET-GAINS-PRIOR>                           0<F1>
<GROSS-ADVISORY-FEES>                          257,412<F1>
<INTEREST-EXPENSE>                                   0<F1>
<GROSS-EXPENSE>                                839,407<F1>
<AVERAGE-NET-ASSETS>                        18,203,108<F2>
<PER-SHARE-NAV-BEGIN>                            12.50<F2>
<PER-SHARE-NII>                                      0<F2>
<PER-SHARE-GAIN-APPREC>                           1.15<F2>
<PER-SHARE-DIVIDEND>                                 0<F2>
<PER-SHARE-DISTRIBUTIONS>                            0<F2>
<RETURNS-OF-CAPITAL>                                 0<F2>
<PER-SHARE-NAV-END>                              13.65<F2>
<EXPENSE-RATIO>                                   1.45<F2>
<FN>
<F1>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND
AS A WHOLE
<F2>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND CLASS A
</FN>


</TABLE>

<TABLE> <S> <C>

<ARTICLE> 6
<CIK> 0001075318
<NAME> SUNAMERICA STRATEGIC INVESTMENT SERIES, INC.
<SERIES>
   <NUMBER> 012
   <NAME> SUNAMERICA TAX MANAGED EQUITY FUND CLASS B

<S>                             <C>
<PERIOD-TYPE>                   8-MOS
<FISCAL-YEAR-END>                          OCT-31-1999
<PERIOD-START>                             MAR-01-1999
<PERIOD-END>                               OCT-31-1999
<INVESTMENTS-AT-COST>                       75,606,117<F1>
<INVESTMENTS-AT-VALUE>                      79,640,649<F1>
<RECEIVABLES>                                1,764,612<F1>
<ASSETS-OTHER>                                  20,106<F1>
<OTHER-ITEMS-ASSETS>                            39,783<F1>
<TOTAL-ASSETS>                              81,465,150<F1>
<PAYABLE-FOR-SECURITIES>                       756,234<F1>
<SENIOR-LONG-TERM-DEBT>                              0<F1>
<OTHER-ITEMS-LIABILITIES>                      233,440<F1>
<TOTAL-LIABILITIES>                            989,674<F1>
<SENIOR-EQUITY>                                      0<F1>
<PAID-IN-CAPITAL-COMMON>                    77,352,975<F1>
<SHARES-COMMON-STOCK>                        2,026,103<F2>
<SHARES-COMMON-PRIOR>                                0<F2>
<ACCUMULATED-NII-CURRENT>                      (1,592)<F1>
<OVERDISTRIBUTION-NII>                               0<F1>
<ACCUMULATED-NET-GAINS>                      (910,439)<F1>
<OVERDISTRIBUTION-GAINS>                             0<F1>
<ACCUM-APPREC-OR-DEPREC>                     4,034,532<F1>
<NET-ASSETS>                                80,475,476<F1>
<DIVIDEND-INCOME>                              366,474<F1>
<INTEREST-INCOME>                               53,668<F1>
<OTHER-INCOME>                                       0<F1>
<EXPENSES-NET>                                 556,539<F1>
<NET-INVESTMENT-INCOME>                      (136,397)<F1>
<REALIZED-GAINS-CURRENT>                     (910,439)<F1>
<APPREC-INCREASE-CURRENT>                    4,034,532<F1>
<NET-CHANGE-FROM-OPS>                        2,987,696<F1>
<EQUALIZATION>                                       0<F1>
<DISTRIBUTIONS-OF-INCOME>                            0<F1>
<DISTRIBUTIONS-OF-GAINS>                             0<F1>
<DISTRIBUTIONS-OTHER>                                0<F1>
<NUMBER-OF-SHARES-SOLD>                      2,060,880<F2>
<NUMBER-OF-SHARES-REDEEMED>                     34,777<F2>
<SHARES-REINVESTED>                                  0<F2>
<NET-CHANGE-IN-ASSETS>                      80,375,476<F1>
<ACCUMULATED-NII-PRIOR>                              0<F1>
<ACCUMULATED-GAINS-PRIOR>                            0<F1>
<OVERDISTRIB-NII-PRIOR>                              0<F1>
<OVERDIST-NET-GAINS-PRIOR>                           0<F1>
<GROSS-ADVISORY-FEES>                          257,412<F1>
<INTEREST-EXPENSE>                                   0<F1>
<GROSS-EXPENSE>                                839,407<F1>
<AVERAGE-NET-ASSETS>                        13,418,741<F2>
<PER-SHARE-NAV-BEGIN>                            12.50<F2>
<PER-SHARE-NII>                                 (0.06)<F2>
<PER-SHARE-GAIN-APPREC>                           1.14<F2>
<PER-SHARE-DIVIDEND>                                 0<F2>
<PER-SHARE-DISTRIBUTIONS>                            0<F2>
<RETURNS-OF-CAPITAL>                                 0<F2>
<PER-SHARE-NAV-END>                              13.58<F2>
<EXPENSE-RATIO>                                   2.10<F2>
<FN>
<F1>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND
AS A WHOLE
<F2>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND
 CLASS B
</FN>


</TABLE>

<TABLE> <S> <C>

<ARTICLE> 6
<CIK> 0001075318
<NAME> SUNAMERICA STRATEGIC INVESTMENT SERIES, INC.
<SERIES>
   <NUMBER> 013
   <NAME> SUNAMERICA TAX MANAGED EQUITY FUND CLASS II

<S>                             <C>
<PERIOD-TYPE>                   8-MOS
<FISCAL-YEAR-END>                          OCT-31-1999
<PERIOD-START>                             MAR-01-1999
<PERIOD-END>                               OCT-31-1999
<INVESTMENTS-AT-COST>                       75,606,117<F1>
<INVESTMENTS-AT-VALUE>                      79,640,649<F1>
<RECEIVABLES>                                1,764,612<F1>
<ASSETS-OTHER>                                  20,106<F1>
<OTHER-ITEMS-ASSETS>                            39,783<F1>
<TOTAL-ASSETS>                              81,465,150<F1>
<PAYABLE-FOR-SECURITIES>                       756,234<F1>
<SENIOR-LONG-TERM-DEBT>                              0<F1>
<OTHER-ITEMS-LIABILITIES>                      233,440<F1>
<TOTAL-LIABILITIES>                            989,674<F1>
<SENIOR-EQUITY>                                      0<F1>
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<SHARES-COMMON-STOCK>                        2,050,672<F2>
<SHARES-COMMON-PRIOR>                                0<F2>
<ACCUMULATED-NII-CURRENT>                      (1,592)<F1>
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<ACCUMULATED-NET-GAINS>                      (910,439)<F1>
<OVERDISTRIBUTION-GAINS>                             0<F1>
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<NET-ASSETS>                                80,475,476<F1>
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<ACCUMULATED-GAINS-PRIOR>                            0<F1>
<OVERDISTRIB-NII-PRIOR>                              0<F1>
<OVERDIST-NET-GAINS-PRIOR>                           0<F1>
<GROSS-ADVISORY-FEES>                          257,412<F1>
<INTEREST-EXPENSE>                                   0<F1>
<GROSS-EXPENSE>                                839,407<F1>
<AVERAGE-NET-ASSETS>                        13,494,791<F2>
<PER-SHARE-NAV-BEGIN>                            12.50<F2>
<PER-SHARE-NII>                                 (0.06)<F2>
<PER-SHARE-GAIN-APPREC>                           1.16<F2>
<PER-SHARE-DIVIDEND>                                 0<F2>
<PER-SHARE-DISTRIBUTIONS>                            0<F2>
<RETURNS-OF-CAPITAL>                                 0<F2>
<PER-SHARE-NAV-END>                              13.60<F2>
<EXPENSE-RATIO>                                   2.10<F2>
<FN>
<F1>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND
AS A WHOLE
<F2>INFORMATION GIVEN PERTAINS TO SUNAMERICA TAX MANAGED EQUITY FUND
CLASS II
</FN>


</TABLE>

Report of Independent Accountants

To the Board of Directors and Shareholders of

SunAmerica Strategic Investment Series, Inc.-Tax Managed Equity Fund

In planning and performing our audit of the financial statements of
SunAmerica Strategic Investment Series, Inc.-Tax Managed Equity Fund (the
"Fund") for the period ended October 31, 1999, we considered its internal
control, including control activities for safeguarding securities, in order
to determine our auditing procedures for the purpose of expressing our
opinion on the financial statements and to comply with the requirements of
Form N-SAR, not to provide assurance on internal control.
The management of the Fund is responsible for establishing and maintaining
internal control.  In fulfilling this responsibility, estimates and
judgments by management are required to assess the expected benefits and
related costs of controls.  Generally, controls that are relevant to an
audit pertain to the entity's objective of preparing financial statements
for external purposes that are fairly presented in conformity with
generally
accepted accounting principles.  Those controls include the safeguarding of
assets against unauthorized acquisition, use or disposition.
Because of inherent limitations in internal control, errors or fraud may
occur and not be detected.  Also, projection of any evaluation of internal
control to future periods is subject to the risk that controls may become
inadequate because of changes in conditions or that the effectiveness of
their design and operation may deteriorate.
Our consideration of internal control would not necessarily disclose all
matters in internal control that might be material weaknesses under
standards established by the American Institute of Certified Public
Accountants.  A material weakness is a condition in which the design or
operation of one or more of the internal control components does not reduce
fraud in amounts that would be material in relation to the financial
statements being audited may occur and not be detected within a timely
functions.  However, we noted no matters involving internal control and its
operation, including controls for safeguarding securities, that we consider
to be material weaknesses as defined above as of October 31, 1999.
This report is intended solely for the information and use of management
and
the Board of Directors, management and the Securities and Exchange
Commission and is not intended to be and should not be used by anyone other
than these specified parties.

PricewaterhouseCoopers LLP

December 13, 1999








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