SUNAMERICA STRATEGIC INVESTMENT SERIES INC
NSAR-B, EX-99.77B, 2000-12-21
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Report of Independent Accountants

To the Shareholders and Board of Directors of
SunAmerica Strategic Investment Series, Inc.

In planning and performing our audit of the financial
statements of SunAmerica Strategic Investment Series,
 Inc. (the "Fund") for the year
 ended October 31, 2000, we considered its internal control,
 including control activities for safeguarding securities,
 in order to determine our auditing procedures for the purpose of
 expressing our opinion on the financial
statements and to comply with the requirements of Form N-SAR
, not to provide assurance on internal control.The management of the Fund
 is responsible for establishing and maintaining
 internal control.  In fulfilling this responsibility,
 estimates and judgments by
 management are required to assess the expected benefits
 and related costs of controls.  Generally, controls that
 are relevant to an audit pertain to the entity's
 objective of preparing financial statements for external
 purposes that are fairly presented in conformity with generally
accepted accounting principles.  Those controls include the
safeguarding of assets against unauthorized acquisition, use or
disposition.
Because of inherent limitations in internal control,
 error or fraud may occur and not be detected.  Also,
 projection of any evaluation of internal control to future
periods is subject to the risk that it may become inadequate
 because of changes in conditions or that the effectiveness
 of the design and operation may deteriorate.

Our consideration of internal control would not necessarily
disclose all matters in internal control that might be material
 weaknesses under standards established
 by the American Institute of Certified Public Accountants.
  A material weakness is a condition in which the design or
 operation of one or more of the internal control components
 does not reduce to a relatively low level
 the risk that misstatements caused by error or fraud in
amounts that would
be material in relation to the financial statements
 being audited may occur and not be detected within
a timely period by employees in the normal course of
 performing their assigned functions.  However, we noted
no matters involving internal control and its operation,
including controls for safeguarding securities,
 that we consider to be material weaknesses as defined
above as of October 31, 2000.
This report is intended solely for the information and
 use of management, the Board of Directors of the Fund,
 and the Securities and Exchange Commission.



PricewaterhouseCoopers LLP
New York, NY 10036
December 15, 2000
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