CELLOMICS INC
S-1/A, EX-3.1.B, 2000-12-14
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                                                 Exhibit 3.1B


         Resolved, that the Board of Directors proposes and declares it
advisable to further amend the Amended and Restated Certificate of Incorporation
of the Company (the "Amended Charter) by amending and restating the initial
section (a) of ARTICLE III, Capital Stock, in its entirety to read as follows:

"(a) The total number of shares of all classes of stock which the Corporation
has authority to issue is Twenty Nine Million Eight Hundred Ninety Four Thousand
Five Hundred (29,894,500), consisting of Twenty Five Million Five Hundred Twenty
Thousand (25,520,000) shares of Common Stock, par value $.01 per share (the
"Common Stock"), and Four Million Three Hundred Seventy-Four Thousand Five
Hundred (4,374,500) shares of Preferred Stock, par value $.01 per share (the
"Preferred Stock"). The number of authorized shares of any such class or classes
may be increased or decreased (but not below the number of shares then
outstanding) by the affirmative vote of the holders of a majority of the
outstanding shares of the Corporation on the basis specified in Part B, Section
5 of this Article III. Upon the filing of this Amendment to the Amended and
Restated Certificate of Incorporation, every outstanding share of Common Stock
shall be split on the basis of 3.19 shares for each one (1) outstanding share of
Common Stock."


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                              AMENDED AND RESTATED

                          CERTIFICATE OF INCORPORATION

                                       OF

                                 CELLOMICS, INC.


         CELLOMICS, INC. (the "Corporation"), a corporation organized under the
laws of the State of Delaware, hereby amends and restates its Certificate of
Incorporation, which was originally filed with the Secretary of State on January
8, 1998 and previously restated and filed with the Secretary of State on January
20, 1998 and February 23, 2000, so that the same shall read, in its entirety, as
follows:


                                    ARTICLE I

                                      NAME

         1. The name of the Corporation is: CELLOMICS, INC.

         2. The address of the Corporation's registered office in the State of
Delaware is 2711 Centerville Road, Suite 400, in the City of Wilmington, County
of New Castle, Delaware, 19808. The Corporation's registered agent at such
address is Corporation Service Company.


                                   ARTICLE II

                                     PURPOSE

         The purpose for which the Corporation is organized is to engage in any
lawful act or activity for which corporations may be organized under the General
Corporation Law of Delaware, as amended from time to time.

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                                   ARTICLE III

                                  CAPITAL STOCK

         (a) The total number of shares of all classes of stock which the
Corporation has authority to issue is Twelve Million Three Hundred Seventy Four
Thousand Five Hundred (12,374,500), consisting of Eight Million (8,000,000)
shares of Common Stock, par value $.01 per share (the "Common Stock"), and Four
Million Three Hundred Seventy-Four Thousand Five Hundred (4,374,500) shares of
Preferred Stock, par value $.01 per share (the "Preferred Stock"). The number of
authorized shares of any such class or classes may be increased or decreased
(but not below the number of shares then outstanding) by the affirmative vote of
the holders of a majority of the outstanding shares of the Corporation on the
basis specified in Part B, Section 5 of this Article III.

         (b) Except as provided in the Amended and Restated Shareholders'
Agreement entered into in connection with the initial issuance of the Series B
Preferred Stock among the Corporation and the shareholders named therein, as may
be further amended from time to time, a copy of which is on file and available
for inspection at the offices of the Corporation (the "Shareholders'
Agreement"), and except for the rights referred to in Section 3(d)(i)(6) hereof
no shareholder shall be entitled as of right to purchase or subscribe for any
unissued shares of the Corporation whether now or hereafter authorized or
whether of a class now existing or of a class hereafter created, or to purchase
or subscribe for any bonds, certificates of indebtedness, debentures, or other
obligations convertible into shares of the Corporation.

         (c) All shares of the Preferred Stock shall be identical except as to
the variations among different series authorized hereinafter. Subject to any
shareholder approval rights hereinafter set forth, the Board of Directors of the
Corporation is expressly authorized to establish series of the Preferred Stock,
to fix the number of shares therein, and to fix the voting powers, designation,
preferences and relative, participating, optional and other special rights and
qualifications, limitations or restrictions of each such series of the Preferred
Stock. Without limitation on the foregoing, the Board of Directors of the
Corporation may establish and designate a series of Preferred Stock of up to One
Million Six Hundred Fifty Thousand (1,650,000) shares to be known as "Series C
Preferred Stock" which shall have the voting powers, preferences and other
rights, qualifications, limitations and restrictions set forth herein.

                                 A. COMMON STOCK

                                    SECTION 1

                                  VOTING RIGHTS

         The holders of shares of Common Stock shall be entitled to one (1) vote
for each share so held with respect to each matter voted on by the shareholders
of the Corporation.



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<PAGE>   4

                                    SECTION 2

                               LIQUIDATION RIGHTS

         Subject to the prior and superior right of the holders of Preferred
Stock, upon any liquidation, dissolution or winding up of the affairs of the
Corporation, the holders of Common Stock, the holders of Series A Preferred
Stock, the holders of Series B Preferred Stock and the holders of Series C
Preferred Stock shall be entitled to receive all remaining assets of the
Corporation. Such assets shall be distributed ratably among the holders of
Common Stock, the holders of Series A Preferred Stock, the holders of Series B
Preferred Stock and the holders of Series C Preferred Stock on the basis of the
number of shares of Common Stock held by each of them and on the number of
shares of Common Stock into which each share of Series A Preferred Stock, Series
B Preferred Stock and Series C Preferred Stock is then convertible.


                                    SECTION 3

                                    DIVIDENDS

         Dividends may be paid on the Common Stock as and when declared by the
Board of Directors, subject, however, to the prior and superior rights of the
holders of Preferred Stock.


                               B. PREFERRED STOCK

         The rights, preferences, privileges and restrictions granted to and
imposed upon the Preferred Stock are as follows:


                                    SECTION 1

                                   DESIGNATION

         A series of Preferred Stock shall be designated and known as "Series A
Preferred Stock," and the number of authorized shares constituting such series
shall be Two Million Twenty-Four Thousand Five Hundred (2,024,500). A series of
Preferred Stock shall be designated and known as "Series B Preferred Stock," and
the number of authorized shares constituting such series shall be Seven Hundred
Thousand (700,000). A series of Preferred Stock shall be designated and known as
"Series C Preferred Stock," and the number of authorized shares constituting
such series shall be One Million Six Hundred Fifty Thousand (1,650,000).



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<PAGE>   5


                                    SECTION 2

                               LIQUIDATION RIGHTS

         (a) Liquidation. In the event of any liquidation, dissolution or
winding up of the Corporation, each holder of shares of Series A Preferred
Stock, each holder of shares of Series B Preferred Stock and each holder of
shares of Series C Preferred Stock shall be entitled to receive, prior and in
preference to any distribution of any of the assets or surplus funds of the
Corporation to the holders of the Common Stock and any other series of Preferred
Stock which is junior to the Series A Preferred Stock, Series B Preferred Stock
and Series C Preferred Stock, by reason of his, her or its ownership thereof, an
amount per share equal to (i) in the case of the Series A Preferred Stock, $5.62
(plus any dividends which, pursuant to Section 6 hereof, have accrued but remain
unpaid at such time), (ii) in the case of the Series B Preferred Stock, $12.07
(plus any dividends which, pursuant to Section 6 hereof, have accrued but remain
unpaid at such time), and (iii) in the case of Series C Preferred Stock, $18.23
(plus any dividends which, pursuant to Section 6 hereof, have accrued but remain
unpaid at such time). After the payment to such holders of such preferential
amounts, any remaining assets and surplus funds shall be distributed to the
holders of Common Stock, the holders of Series A Preferred Stock, the holders of
Series B Preferred Stock and the holders of Series C Preferred Stock in
accordance with Section 2 of Part A of this Article III.

         (b) Pro Rata Distribution. If the assets or surplus funds to be
distributed to (i) the holders of the Series A Preferred Stock under Section
2(a), (ii) the holders of the Series B Preferred Stock under Section 2(a), (iii)
the holders of the Series C Preferred Stock under Section 2(a), and (iv) the
holders of any other series of Preferred Stock ranking on a parity with the
Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock
are insufficient to permit the payment to such holders of their full
preferential amount, the assets and surplus funds legally available for
distribution shall be distributed ratably among (i) the holders of the Series A
Preferred Stock (to the extent provided in Section 2(a) hereof), (ii) the
holders of the Series B Preferred Stock (to the extent provided in Section 2(a)
hereof), (iii) the holders of the Series C Preferred Stock (to the extent
provided in Section 2(a) hereof), and (iv) the holders of such other series of
Preferred Stock in proportion to the full preferential amount each such holder
is otherwise entitled to receive.

         (c) Series A Preferred Stock, Series B Preferred Stock and Series C
Preferred Stock Priority. All of the preferential amounts to be paid to (i) the
holders of the Series A Preferred Stock under this Section 2, (ii) the holders
of the Series B Preferred Stock under this Section 2, (iii) the holders of the
Series C Preferred Stock under this Section 2, and (iv) the holders of any other
series of Preferred Stock ranking on a parity with the Series A Preferred Stock,
Series B Preferred Stock and the Series C Preferred Stock shall be paid or set
apart for payment before the payment or setting apart for payment of any amount
for, or the distribution of any assets or surplus funds of the Corporation to,
the holders of the Common Stock and any other series of Preferred Stock which is
junior to the Series A Preferred Stock, Series B Preferred Stock and Series C
Preferred Stock in connection with such liquidation, dissolution or winding up.

         (d) Consolidation, Merger, Sale of Assets. A consolidation or merger of
the Corporation with or into another corporation, or a conveyance of all or
substantially all of the assets of the



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Corporation, shall be regarded as a liquidation, dissolution or winding up of
the affairs of the Corporation within the meaning of Article III(A)(2) and
Section 2(a) of this Article III(B) unless, (i) upon consummation of such
consolidation or merger or sale of assets, the holders of voting securities of
the Corporation own directly or indirectly more than fifty percent (50%) of the
voting power to elect directors of the consolidated or surviving or acquiring
corporation or (ii) with respect to the Series A Preferred Stock and the Series
B Preferred Stock, the holders of at least a majority of the voting power of all
the outstanding shares of Series A Preferred Stock and Series B Preferred Stock
(voting together as a separate class) and, with respect to the Series C
Preferred Stock, the holders of at least a majority of the voting power of all
the outstanding shares of the Series C Preferred Stock (voting as a separate
class), determine otherwise no later than thirty (30) business days prior to the
effective date of such event, provided, however, that each holder of Series A
Preferred Stock, each holder of Series B Preferred Stock, and each holder of
Series C Preferred Stock shall have the right to elect the benefits of the
provisions of Section 3(d)(vii) hereof in lieu of receiving payment in any such
deemed liquidation, dissolution or winding up of the Corporation pursuant to
this Section 2, notice of which election shall be submitted in writing to the
Corporation at its principal offices no later than five (5) business days before
the effective date of such event. Any securities to be delivered to the holders
of the Series A Preferred Stock, the holders of the Series B Preferred Stock and
the holders of Series C Preferred Stock upon the closing of any such
consolidation, merger, sale or transfer shall be valued as follows:

                  A. For securities not subject to restrictions on transfer
under an investment letter or other similar restrictions on free marketability:

                  (i) If traded on a securities exchange, the value shall be
         deemed to be the average of the closing prices of such securities on
         such exchange over the thirty (30) day period ending three (3) days
         prior to such closing;

                  (ii) If actively traded over-the-counter, the value shall be
         deemed to be the average of the closing bid or sale prices (whichever
         are applicable) over the thirty (30) day period ending three (3) days
         prior to such closing; and

                  (iii) If there is no active public market, the value shall be
         the fair market value thereof, as mutually determined by the
         Corporation and the holders of at least two-thirds (2/3's) of the
         voting power of all then outstanding shares of Series A Preferred
         Stock, Series B Preferred Stock and Series C Preferred Stock (voting
         together as a separate class) which would be entitled to receive such
         securities or the same type of securities.

                  B. The method of valuation of securities subject to an
investment letter or other restrictions on free marketability shall be to make
an appropriate discount from the market value determined as above in subsection
2A to reflect the approximate fair market value thereof, as mutually determined
by the Corporation and the holders of at least two-thirds (2/3's) of the voting
power of all then outstanding shares of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock (voting together as a separate
class) which would be entitled to receive such securities or the same type of
securities.



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<PAGE>   7

                                    SECTION 3

                                   CONVERSION

         The holders of the Series A Preferred Stock, the holders of the Series
B Preferred Stock and the holders of Series C Preferred Stock shall have
conversion rights as follows (the "Conversion Rights"):

         (a) Right to Convert. Each share of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock shall be convertible, without the
payment of any additional consideration by the holder thereof, at the option of
the holder thereof, at the office of the Corporation or any transfer agent for
the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred
Stock, into such number of fully paid and nonassessable shares of Common Stock
as is determined (i) in the case of the Series A Preferred Stock, by dividing
$5.62 by the Series A Conversion Price, determined as hereinafter provided, in
effect at the time of conversion, (ii) in the case of the Series B Preferred
Stock, by dividing $12.07 by the Series B Conversion Price, determined as
hereinafter provided, in effect at the time of conversion, and (iii) in the case
of the Series C Preferred Stock, by dividing $18.23 by the Series C Conversion
Price, determined as hereinafter provided, in effect at the time of conversion.
If more than one share of the Series A Preferred Stock, Series B Preferred Stock
or Series C Preferred Stock shall be surrendered for conversion at the same time
by the same holder of record, the number of full shares that shall be issuable
upon the conversion thereof shall be computed on the basis of the total number
of shares of the Series A Preferred Stock, Series B Preferred Stock or Series C
Preferred Stock so surrendered. Each share of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock shall be so convertible at any time
after the date of issuance of such share. The price at which shares of Common
Stock shall be deliverable upon conversion of Series A Preferred Stock without
the payment of any additional consideration by the holder thereof (the "Series A
Conversion Price") shall initially be $5.62 per share of Common Stock. The price
at which shares of Common Stock shall be deliverable upon conversion of Series B
Preferred Stock without the payment of any additional consideration by the
holder thereof (the "Series B Conversion Price") shall initially be $12.07 per
share of Common Stock. The price at which shares of Common Stock shall be
deliverable upon conversion of Series C Preferred Stock without the payment of
any additional consideration by the holder thereof (the "Series C Conversion
Price") shall initially be $18.23 per share of Common Stock. The Series A
Conversion Price, the Series B Conversion Price and the Series C Conversion
Price are collectively referred to as the "Conversion Prices." Such initial
Conversion Prices shall be subject to adjustment, in order to adjust the number
of shares of Common Stock into which the Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock are convertible, as hereinafter
provided.

         (b) Automatic Conversion.

                  (i) At the Option of the Corporation.

                           (1) Series A Preferred Stock. Each share of Series A
                  Preferred Stock shall, at the Corporation's option, be
                  converted into shares of Common Stock at the



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<PAGE>   8

                  then effective Series A Conversion Price upon the closing of a
                  firm commitment underwritten public offering pursuant to an
                  effective registration statement under the Securities Act of
                  1933, as amended, covering the offer and sale of Common Stock
                  for the account of the Corporation to the public at an
                  aggregate offering price resulting in gross proceeds to the
                  Corporation as seller of not less than $15,000,000, before
                  deducting underwriting commissions, provided that the offering
                  price per share of Common Stock is not less than three (3)
                  times the original Series A Conversion Price (the "Series A
                  Automatic Conversion Price"). The Corporation may exercise its
                  option pursuant to this Section 3(b)(i)(1) only with respect
                  to all, and not less than all, outstanding shares of Series A
                  Preferred Stock. In the event the Corporation elects to cause
                  the conversion of Series A Preferred Stock pursuant to this
                  Section 3(b)(i)(1), (i) it shall give to each holder of Series
                  A Preferred Stock notice of such conversion at least fifteen
                  (15) days prior to the anticipated closing of such a public
                  offering, and (ii) the party or parties entitled to receive
                  the Common Stock issuable upon such conversion of the Series A
                  Preferred Stock shall not be deemed to have converted their
                  Series A Preferred Stock until immediately prior to the
                  closing of such offering.

                           (2) Series B Preferred Stock. Each share of Series B
                  Preferred Stock shall, at the Corporation's option, be
                  converted into shares of Common Stock at the then effective
                  Series B Conversion Price upon the closing of a firm
                  commitment underwritten public offering pursuant to an
                  effective registration statement under the Securities Act of
                  1933, as amended, covering the offer and sale of Common Stock
                  for the account of the Corporation to the public at an
                  aggregate offering price resulting in gross proceeds to the
                  Corporation as seller of not less than $20,000,000, before
                  deducting underwriting commissions, provided that the offering
                  price per share of Common Stock is not less than two and
                  one-half (2.5) times the original Series B Conversion Price
                  (the "Series B Automatic Conversion Price"). The Corporation
                  may exercise its option pursuant to this Section 3(b)(i)(2)
                  only with respect to all, and not less than all, outstanding
                  shares of Series B Preferred Stock and only if the Corporation
                  has concurrently therewith or prior thereto exercised its
                  option pursuant to Section 3(b)(i)(1) with respect to all (and
                  not less than all) outstanding shares of Series A Preferred
                  Stock. In the event the Corporation elects to cause the
                  conversion of Series B Preferred Stock pursuant to this
                  Section 3(b)(i)(2), (i) it shall give to each holder of Series
                  B Preferred Stock notice of such conversion at least fifteen
                  (15) days prior to the anticipated closing of such a public
                  offering, and (ii) the party or parties entitled to receive
                  the Common Stock issuable upon such conversion of the Series B
                  Preferred Stock shall not be deemed to have converted their
                  Series B Preferred Stock until immediately prior to the
                  closing of such offering.

                           (3) Series C Preferred Stock. Each share of Series C
                  Preferred Stock shall, at the Corporation's option, be
                  converted into shares of Common Stock at the then effective
                  Series C Conversion Price upon the closing of a firm
                  commitment underwritten public offering pursuant to an
                  effective registration statement under the Securities Act of
                  1933, as amended, covering the offer and sale of Common Stock
                  for



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                  the account of the Corporation to the public at an aggregate
                  offering price resulting in gross proceeds to the Corporation
                  as seller of not less than $20,000,000, before deducting
                  underwriting commissions, provided that the offering price per
                  share of Common Stock is not less than two (2) times the
                  original Series C Automatic Conversion Price (the "Series C
                  Automatic Conversion Price"). The Corporation may exercise its
                  option pursuant to this Section 3(b)(i)(3) only with respect
                  to all, and not less than all, outstanding shares of Series C
                  Preferred Stock and only if the Corporation has concurrently
                  therewith or prior thereto exercised its option pursuant to
                  Section 3(b)(i)(1) and (2) with respect to all (and not less
                  than all) outstanding shares of Series A Preferred Stock and
                  Series B Preferred Stock. In the event the Corporation elects
                  to cause the conversion of Series C Preferred Stock pursuant
                  to this Section 3(b)(i)(3), (i) it shall give to each holder
                  of Series C Preferred Stock notice of such conversion at least
                  fifteen (15) days prior to the anticipated closing of such a
                  public offering, and (ii) the party or parties entitled to
                  receive the Common Stock issuable upon such conversion of the
                  Series C Preferred Stock shall not be deemed to have converted
                  their Series C Preferred Stock until immediately prior to the
                  closing of such offering.

                  (ii) At the Option of a Supermajority of the Holders of Series
         A Preferred Stock, Series B Preferred Stock and Series C Preferred
         Stock. Each share of Series A Preferred Stock and Series B Preferred
         Stock shall, upon the vote of the holders of at least two-thirds
         (2/3's) of the voting power of all then outstanding shares of Series A
         Preferred Stock and Series B Preferred Stock (voting together as a
         separate class), be converted into shares of Common Stock at the then
         effective Series A Conversion Price or Series B Conversion Price (as
         the case may be). Each share of Series C Preferred Stock shall, upon
         vote of the holders of at least two-thirds (2/3) of the voting power of
         all then outstanding shares of Series C Preferred Stock (voting as a
         separate class), be converted into shares of Common Stock at the then
         effective Series C Conversion Price. Such conversion shall occur, and
         the party or parties entitled to receive the Common Stock issuable upon
         such conversion of the Series A Preferred Stock, the Series B Preferred
         Stock and the Series C Preferred Stock shall be deemed to have
         converted their shares of Series A Preferred Stock, Series B Preferred
         Stock and/or Series C Preferred Stock, on the date specified by such
         vote, which shall be no earlier than the fifth (5th) business day after
         the date of such vote.

         (c) Mechanics of Conversion. Each party who holds of record Series A
Preferred Stock, Series B Preferred Stock or Series C Preferred Stock at the
time of any conversion (whether optional or mandatory) shall be entitled to any
dividends which, pursuant to Section 6 hereof, have accrued but remain unpaid at
such time. Such dividends shall be paid to all such holders within thirty (30)
days of the conversion. No fractional shares of Common Stock shall be issued
upon conversion of the Series A Preferred Stock, Series B Preferred Stock or
Series C Preferred Stock. In lieu of any fractional share to which the holder
would otherwise be entitled, the Corporation shall pay cash equal to such
fraction multiplied by the then effective Series A Conversion Price, Series B
Conversion Price or Series C Conversion Price (as the case may be). Except in
the case of a conversion at the option of the Corporation pursuant to Section
3(b), before any holder of Series A Preferred Stock, Series B Preferred Stock or
Series C Preferred Stock shall be entitled to convert the



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same into full shares of Common Stock, he, she or it shall surrender the
certificate or certificates therefor, duly endorsed, at the office of the
Corporation or of any transfer agent for the Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock, and shall give written notice to
the Corporation at such office that he, she or it elects to convert the same.
Upon the date of a conversion pursuant to Section 3(b), any party entitled to
receive the shares of Common Stock issuable upon such conversion shall be
treated for all purposes as the record holder of such shares of Common Stock on
such date, whether or not such holder has surrendered the certificate or
certificates for such holder's shares of Series A Preferred Stock, Series B
Preferred Stock or Series C Preferred Stock. A holder surrendering his, her or
its certificate or certificates shall notify the Corporation of his, her or its
name or the name or names of his, her or its nominees in which he, she or it
wishes the certificate or certificates for shares of Common Stock to be issued.
If the person or persons in whose name any certificate for shares of Common
Stock issuable upon such conversion shall be other than the registered holder or
holders of the Series A Preferred Stock, Series B Preferred Stock or Series C
Preferred Stock being converted, the Corporation's obligation under this Section
3(c) shall be subject to the payment and satisfaction by such registered holder
or holders of any and all transfer taxes in connection with the conversion and
issuance of such Common Stock. The Corporation shall, as soon as practicable
thereafter (and, in any event, within ten (10) days of such surrender), issue
and deliver at such office to such holder of Series A Preferred Stock, Series B
Preferred Stock or Series C Preferred Stock, or to his, her or its nominee or
nominees, a certificate or certificates for the number of shares of Common Stock
to which he, she or it shall be entitled as aforesaid, together with cash in
lieu of any fraction of a share. Except in the case of a conversion pursuant to
Section 3(b), such conversion shall be deemed to have been made immediately
prior to the close of business on the date of such surrender of the shares of
Series A Preferred Stock, Series B Preferred Stock or Series C Preferred Stock
to be converted, and the party or parties entitled to receive the shares of
Common Stock issuable upon conversion shall be treated for all purposes as the
record holder or holders of such shares of Common Stock on such date.

         (d) Adjustments to Conversion Prices for Diluting Issues:

                  (i) Special Definitions. For purposes of this Section 3(d),
         the following definitions shall apply:

                           (1) "Option" shall mean options, warrants or other
                  rights to subscribe for, purchase or otherwise acquire either
                  Common Stock or Convertible Securities.

                           (2) "Original Series A Issue Date" shall mean the
                  first date on which a share of Series A Preferred Stock shall
                  have been issued.

                           (3) "Original Series B Issue Date" shall mean the
                  first date on which a share of Series B Preferred Stock shall
                  have been issued.

                           (4) "Original Series C Issue Date" shall mean the
                  first date on which a share of Series C Preferred Stock shall
                  have been issued.



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                           (5) "Convertible Securities" shall mean any evidences
                  of indebtedness, shares (other than Common Stock, Series A
                  Preferred Stock, Series B Preferred Stock and Series C
                  Preferred Stock outstanding as of the date of this Amended and
                  Restated Certificate of Incorporation) of capital stock or
                  other securities directly or indirectly convertible into or
                  exchangeable for Common Stock.

                           (6) "Additional Shares of Common Stock" shall mean
                  any or all shares of Common Stock issued (or, pursuant to
                  Section 3(d)(iii), deemed to be issued) by the Corporation
                  after the Original Series C Issue Date, other than shares of
                  Common Stock issued or issuable:

                  (A)      upon conversion of shares of Series A Preferred
                           Stock, Series B Preferred Stock or Series C Preferred
                           Stock; or

                  (B)      (i) upon exercise of warrants to purchase Common
                           Stock or Preferred Stock which were issued or for
                           which an agreement to issue or giving rise to the
                           obligation to issue was entered into prior to the
                           date of filing of this Amended and Restated
                           Certificate of Incorporation with the Delaware
                           Secretary of State (the "Initial Filing Date") or
                           (ii) to Beckman Coulter, Inc. pursuant to the
                           anti-dilution rights created in that certain Common
                           Stock Purchase Agreement dated June 9, 2000, a copy
                           of which is on file and available for inspection at
                           the offices of the Corporation, pursuant to which the
                           Corporation sold shares of Common Stock to Beckman
                           Coulter, Inc.; or

                  (C)      to employees, officers or directors of, or
                           consultants to, the Corporation pursuant to any stock
                           plan approved by the holders of at least a majority
                           of the outstanding Preferred Stock in respect of any
                           stock option plan adopted prior to the Initial Filing
                           Date or by the holders of at least a majority of the
                           outstanding Series A Preferred Stock, Series B
                           Preferred Stock and Series C Preferred Stock (voting
                           together as a separate class) in respect of any stock
                           option plan adopted on or after the Initial Filing
                           Date, provided that the number of shares so issued or
                           issuable between the Initial Filing Date and the
                           earlier of (i) the first anniversary of the original
                           Series C Issue Date, or (ii) upon the closing of a
                           firm commitment underwritten public offering pursuant
                           to an effective registration statement under the
                           Securities Act of 1933, as amended, covering the
                           offer and sale of Common Stock for the account of the
                           Corporation to the public at an aggregate offering
                           price and price per share sufficient to trigger
                           conversion under Section 3(b)(i)(3) above shall not
                           exceed 893,057 (as adjusted for stock splits,
                           combinations and other similar events affecting the
                           Common Stock), plus such additional number of shares
                           of Common Stock as may be approved by the holders of
                           at least a majority of the outstanding Series A
                           Preferred Stock, Series B Preferred Stock and Series
                           C Preferred Stock (voting together as a separate
                           class) (the "Reserved Employee Shares"); all of such
                           plans, options and grants collectively referred to as
                           the "Plans"; or



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<PAGE>   12

                  (D)      to financial institutions or other lenders in
                           connection with borrowing or lease financing
                           arrangements of the Company, provided that such
                           issuances are unanimously approved by the Board of
                           Directors; or

                  (E)      to Carl Zeiss Holding Co., Inc., pursuant to its
                           anti-dilution rights existing as of the Original
                           Series A Issue Date; or

                  (F)      upon the closing of a firm commitment underwritten
                           public offering pursuant to an effective registration
                           statement under the Securities Act of 1933, as
                           amended, covering the offer and sale of Common Stock
                           for the account of the Corporation to the public.

                  (ii) No Adjustment of Conversion Price.

                           (1)      Series A Preferred Stock. Subject to the
                                    provisions of Section 3(d)(iii)(2) and
                                    Section 3(d)(vi) below, no adjustment in the
                                    number of shares of Common Stock into which
                                    any share of Series A Preferred Stock is
                                    convertible shall be made, by adjustment in
                                    the Series A Conversion Price in respect of
                                    the issuance of Additional Shares of Common
                                    Stock or otherwise, unless the consideration
                                    per share for an Additional Share of Common
                                    Stock issued (or deemed to be issued
                                    pursuant to Section 3(d)(iii)) by the
                                    Corporation is less than the Series A
                                    Conversion Price in effect on the date of,
                                    and immediately prior to, the issue of such
                                    Additional Share of Common Stock.

                           (2)      Series B Preferred Stock. Subject to the
                                    provisions of Section 3(d)(iii)(2) and
                                    Section 3(d)(vi) below, no adjustment in the
                                    number of shares of Common Stock into which
                                    any share of Series B Preferred Stock is
                                    convertible shall be made, by adjustment in
                                    the Series B Conversion Price in respect of
                                    the issuance of Additional Shares of Common
                                    Stock or otherwise, unless the consideration
                                    per share for an Additional Share of Common
                                    Stock issued (or deemed to be issued
                                    pursuant to Section 3(d)(iii)) by the
                                    Corporation is less than the Series B
                                    Conversion Price in effect on the date of,
                                    and immediately prior to, the issue of such
                                    Additional Share of Common Stock.

                           (3)      Series C Preferred Stock. Subject to the
                                    provisions of Section 3(d)(iii)(2) and
                                    Section 3(d)(vi) below, no adjustment in the
                                    number of shares of Common Stock into which
                                    any share of Series C Preferred Stock is
                                    convertible shall be made, by adjustment in
                                    the Series C Conversion Price in respect of
                                    the issuance of Additional Shares of Common
                                    Stock or otherwise, unless the consideration
                                    per share for an Additional Share of Common
                                    Stock issued (or deemed to be issued
                                    pursuant to Section 3(d)(iii)) by the
                                    Corporation is less than the Series C
                                    Conversion Price in effect on the date of,
                                    and immediately prior to, the issue of such
                                    Additional Share of Common Stock.



                                       11
<PAGE>   13



                  (iii) Issue of Securities Deemed Issue of Additional Shares of
         Common Stock.

                           (1) Options and Convertible Securities. In the event
                  the Corporation at any time or from time to time after the
                  Original Series C Issue Date shall issue any Options or
                  Convertible Securities or shall fix a record date for the
                  determination of holders of any class of securities entitled
                  to receive any such Options or Convertible Securities, then
                  the maximum number of shares (as set forth in the instrument
                  relating thereto without regard to any provisions contained
                  therein for a subsequent adjustment of such number) of Common
                  Stock issuable upon the exercise of such Options or, in the
                  case of Convertible Securities and Options therefor, the
                  conversion or exchange of such Convertible Securities, shall
                  be deemed to be Additional Shares of Common Stock issued as of
                  the time of such issue or, in case such a record date shall
                  have been fixed, as of the close of business on such record
                  date, provided that such Additional Shares of Common Stock
                  shall not be deemed to have been issued unless (i) with
                  respect to the dilution adjustment for Series A Preferred
                  Stock, the consideration per share (determined pursuant to
                  Section 3(d)(v) hereof) of such Additional Shares of Common
                  Stock would be less than the Series A Conversion Price in
                  effect on the date of and immediately prior to such issue, or
                  such record date, as the case may be, (ii) with respect to the
                  dilution adjustment for Series B Preferred Stock, the
                  consideration per share (determined pursuant to Section
                  3(d)(v) hereof) of such Additional Shares of Common Stock
                  would be less than the Series B Conversion Price in effect on
                  the date of and immediately prior to such issue, or such
                  record date, as the case may be, or (iii) with respect to the
                  dilution adjustment for Series C Preferred Stock, the
                  consideration per share (determined pursuant to Section
                  3(d)(v) hereof) of such Additional Shares of Common Stock
                  would be less than the Series C Conversion Price in effect on
                  the date of and immediately prior to such issue, or such
                  record date, as the case may be, and provided, further, that
                  in any such case in which Additional Shares of Common Stock
                  are deemed to be issued:

                  (A)      no further adjustment in the Conversion Prices shall
                           be made upon the subsequent issue of Convertible
                           Securities or shares of Common Stock upon the
                           exercise of such Options or conversion or exchange of
                           such Convertible Securities;

                  (B)      if such Options or Convertible Securities by their
                           terms provide, with the passage of time, pursuant to
                           any provisions designed to protect against dilution,
                           or otherwise, for any increase or decrease in the
                           consideration payable to the Corporation, or increase
                           or decrease in the number of shares of Common Stock
                           issuable, upon the exercise, conversion or exchange
                           thereof, the Conversion Prices computed upon the
                           original issue thereof (or upon the occurrence of a
                           record date with respect thereto), and any subsequent
                           adjustments based thereon, shall, upon any such
                           increase or decrease becoming effective, be
                           recomputed to reflect such increase or



                                       12
<PAGE>   14

                           decrease insofar as it affects such Options or the
                           rights of conversion or exchange under such
                           Convertible Securities;

                  (C)      upon the expiration of any such Options or any rights
                           of conversion or exchange under such Convertible
                           Securities which shall not have been exercised, the
                           Conversion Prices computed upon the original issue
                           thereof (or upon the occurrence of a record date with
                           respect thereto), and any subsequent adjustments
                           based thereon, shall, upon such expiration, be
                           recomputed as if such Options or Convertible
                           Securities, as the case may be, were never issued;

                  (D)      no readjustment pursuant to clause (B) or (C) above
                           shall have the effect of:

                           (x)      increasing the Series A Conversion Price to
                                    an amount which exceeds the lower of (i) the
                                    Series A Conversion Price on the original
                                    date on which an adjustment was made
                                    pursuant to this Section 3(d)(iii)(l), or
                                    (ii) the Series A Conversion Price that
                                    would have resulted from any issuance of
                                    Additional Shares of Common Stock between
                                    such original adjustment date and the date
                                    on which a readjustment is made pursuant to
                                    clause (B) or (C) above, or

                           (y)      increasing the Series B Conversion Price to
                                    an amount which exceeds the lower of (i) the
                                    Series B Conversion Price on the original
                                    date on which an adjustment was made
                                    pursuant to this Section 3(d)(iii)(1), or
                                    (ii) the Series B Conversion Price that
                                    would have resulted from any issuance of
                                    Additional Shares of Common Stock between
                                    such original adjustment date and the date
                                    on which a readjustment is made pursuant to
                                    clause (B) or (C) above, or

                           (z)      increasing the Series C Conversion Price to
                                    an amount which exceeds the lower of (i) the
                                    Series C Conversion Price on the original
                                    date on which an adjustment was made
                                    pursuant to this Section 3(d)(iii)(1), or
                                    (ii) the Series C Conversion Price that
                                    would have resulted from any issuance of
                                    Additional Shares of Common Stock between
                                    such original adjustment date and the date
                                    on which a readjustment is made pursuant to
                                    clause (B) or (C) above;

                  (E)      in the case of any Options which expire by their
                           terms not more than thirty (30) days after the date
                           of issue thereof, no adjustment of the Conversion
                           Prices shall be made until the expiration or exercise
                           of all such Options, whereupon such adjustment shall
                           be made in the same manner provided in clause (C)
                           above; and

                  (F)      if such record date shall have been fixed and such
                           Options or Convertible Securities are not issued on
                           the date fixed therefor, the adjustment or



                                       13
<PAGE>   15

                           adjustments previously made in the Conversion Prices
                           which became effective on such record date shall be
                           canceled as of the close of business on such record
                           date, and thereafter the Conversion Prices shall be
                           adjusted pursuant to this Section 3(d)(iii) as of the
                           actual date of their issuance.

                           (2) Stock Dividends, Stock Distributions and
                  Subdivisions. In the event the Corporation at any time or from
                  time to time after the Original Series C Issue Date shall
                  declare or pay any dividend or make any other distribution on
                  the Common Stock payable in Common Stock, or effect a
                  subdivision of the outstanding shares of Common Stock (by
                  reclassification or otherwise than by payment of a dividend in
                  Common Stock), then and in any such event, Additional Shares
                  of Common Stock shall be deemed to have been issued:

                  (A)      in the case of any such dividend or distribution,
                           immediately after the close of business on the record
                           date for the determination of holders of any class of
                           securities entitled to receive such dividend or
                           distribution, or

                  (B)      in the case of any such subdivision, at the close of
                           business on the date immediately prior to the date
                           upon which such corporate action becomes effective.

                           If such record date shall have been fixed and such
                           dividend shall not have been fully paid on the date
                           fixed for the payment thereof, the adjustments
                           previously made in the Conversion Prices which became
                           effective on such record date shall be canceled as of
                           the close of business on such record date, and
                           thereafter the Conversion Prices shall be adjusted
                           pursuant to this Section 3(d)(iii) as of the time of
                           actual payment of such dividend.

                  (iv) Adjustment of Conversion Prices Upon Issuance of
         Additional Shares of Common Stock.

                           (1) Adjustment of Series A Conversion Price. In the
                  event the Corporation shall issue Additional Shares of Common
                  Stock (including Additional Shares of Common Stock deemed to
                  be issued with respect to the dilution adjustment for Series A
                  Preferred Stock pursuant to Section 3(d)(iii)(1), but
                  excluding Additional Shares of Common Stock deemed to be
                  issued pursuant to Section 3(d)(iii)(2), which event is dealt
                  with in Section 3(d)(vi) hereof) without consideration or for
                  a consideration per share less than the Series A Conversion
                  Price in effect on the date of and immediately prior to such
                  issue, then such Series A Conversion Price shall be reduced,
                  concurrently with such issue, to the price determined by
                  dividing (i) an amount equal to the sum of (a) the number of
                  shares of Common Stock outstanding immediately prior to such
                  issue or sale and the number of shares of Common Stock
                  issuable upon conversion of all Series A Preferred Stock,
                  Series B Preferred Stock and Series C Preferred Stock and any
                  Convertible Securities multiplied by the then existing Series
                  A Conversion Price and



                                       14
<PAGE>   16

                  (b) the consideration, if any, received by the Corporation
                  upon such issue or sale, by (ii) the total number of shares of
                  Common Stock outstanding immediately after such issue or sale
                  and the number of shares of Common Stock issuable upon
                  conversion of all Series A Preferred Stock, Series B Preferred
                  Stock and Series C Preferred Stock and any Convertible
                  Securities.

                           (2) Adjustment of Series B Conversion Price. In the
                  event the Corporation shall issue Additional Shares of Common
                  Stock (including Additional Shares of Common Stock deemed to
                  be issued with respect to the dilution adjustment for Series B
                  Preferred Stock pursuant to Section 3(d)(iii)(1), but
                  excluding Additional Shares of Common Stock deemed to be
                  issued pursuant to Section 3(d)(iii)(2), which event is dealt
                  with in Section 3(d)(vi) hereof) without consideration or for
                  a consideration per share less than the Series B Conversion
                  Price in effect on the date of and immediately prior to such
                  issue, then such Series B Conversion Price shall be reduced,
                  concurrently with such issue, to the price determined by
                  dividing (i) an amount equal to the sum of (a) the number of
                  shares of Common Stock outstanding immediately prior to such
                  issue or sale and the number of shares of Common Stock
                  issuable upon conversion of all Series A Preferred Stock,
                  Series B Preferred Stock and Series C Preferred Stock and any
                  Convertible Securities multiplied by the then existing Series
                  B Conversion Price and (b) the consideration, if any, received
                  by the Corporation upon such issue or sale, by (ii) the total
                  number of shares of Common Stock outstanding immediately after
                  such issue or sale and the number of shares of Common Stock
                  issuable upon conversion of all Series A Preferred Stock,
                  Series B Preferred Stock and Series C Preferred Stock and any
                  Convertible Securities.

                           (3) Adjustment of Series C Conversion Price. In the
                  event the Corporation shall issue Additional Shares of Common
                  Stock (including Additional Shares of Common Stock deemed to
                  be issued with respect to the dilution adjustment for Series C
                  Preferred Stock pursuant to Section 3(d)(iii)(1), but
                  excluding Additional Shares of Common Stock deemed to be
                  issued pursuant to Section 3(d)(iii)(2), which event is dealt
                  with in Section 3(d)(vi) hereof) without consideration or for
                  a consideration per share less than the Series C Conversion
                  Price in effect on the date of and immediately prior to such
                  issue, then such Series C Conversion Price shall be reduced,
                  concurrently with such issue, to the price determined by
                  dividing (i) an amount equal to the sum of (a) the number of
                  shares of Common Stock outstanding immediately prior to such
                  issue or sale and the number of shares of Common Stock
                  issuable upon conversion of all Series A Preferred Stock,
                  Series B Preferred Stock and Series C Preferred Stock and any
                  Convertible Securities multiplied by the then existing Series
                  C Conversion Price and (b) the consideration, if any, received
                  by the Corporation upon such issue or sale, by (ii) the total
                  number of shares of Common Stock outstanding immediately after
                  such issue or sale and the number of shares of Common Stock
                  issuable upon conversion of all Series A Preferred Stock,
                  Series B Preferred Stock and Series C Preferred Stock and any
                  Convertible Securities.



                                       15
<PAGE>   17

                  (v) Determination of Consideration. For purposes of this
         Section 3(d), the consideration received by the Corporation for the
         issue of any Additional Shares of Common Stock shall be computed as
         follows:

                           (1) Cash and Property: Such consideration shall:

                  (A)      insofar as it consists of cash, be the aggregate
                           amount of cash received by the Corporation excluding
                           amounts paid or payable for accrued interest or
                           accrued dividends;

                  (B)      insofar as it consists of property other than cash,
                           be computed at the fair value thereof at the time of
                           such issue, as determined in good faith by the Board
                           of Directors; and

                  (C)      in the event Additional Shares of Common Stock are
                           issued together with other shares of securities or
                           other assets of the Corporation for a single
                           undivided consideration, be the proportion of such
                           consideration so received allocable to such
                           Additional Shares of Common Stock, computed as
                           provided in clauses (A) and (B) above, as determined
                           in good faith by the Board of Directors.

                           (2) Options and Convertible Securities. The
                  consideration per share received by the Corporation for
                  Additional Shares of Common Stock deemed to have been issued
                  pursuant to Section 3(d)(iii)(1) shall be determined by
                  dividing

                           (x)      the total amount, if any, received or
                                    receivable by the Corporation as
                                    consideration for the issue of such Options
                                    or Convertible Securities, plus the minimum
                                    aggregate amount of additional consideration
                                    (as set forth in the instruments relating
                                    thereto, without regard to any provision
                                    contained therein for a subsequent
                                    adjustment of such consideration) payable to
                                    the Corporation upon the exercise of such
                                    Options or the conversion or exchange of
                                    such Convertible Securities, or in the case
                                    of Options for Convertible Securities, the
                                    exercise of such Options for Convertible
                                    Securities and the conversion or exchange of
                                    such Convertible Securities, by

                           (y)      the maximum number of shares of Common Stock
                                    (as set forth in the instruments relating
                                    thereto, without regard to any provision
                                    contained therein for a subsequent
                                    adjustment of such number) issuable upon the
                                    exercise of such Options or the conversion
                                    or exchange of such Convertible Securities.

                  (vi) Adjustment for Stock Dividends, Stock Distributions,
         Subdivisions, Combinations or Consolidations of Common Stock.



                                       16
<PAGE>   18

                           (1) Stock Dividends, Stock Distributions or
                  Subdivisions. In the event the Corporation shall issue
                  Additional Shares of Common Stock pursuant to Section
                  3(d)(iii)(2) in a stock dividend, other stock distribution or
                  subdivision, the Conversion Prices in effect immediately prior
                  to such stock dividend, stock distribution or subdivision
                  shall, concurrently with the effectiveness of such stock
                  dividend, stock distribution or subdivision, be
                  proportionately decreased to adjust equitably for such
                  dividend, distribution or subdivision.

                           (2) Combinations or Consolidations. In the event the
                  outstanding shares of Common Stock shall be combined or
                  consolidated, by reclassification or otherwise, into a lesser
                  number of shares of Common Stock, the Conversion Prices in
                  effect immediately prior to such combination or consolidation
                  shall, concurrently with the effectiveness of such combination
                  or consolidation, be proportionately increased to adjust
                  equitably for such combination or consolidation.

                  (vii) Adjustment for Merger or Reorganization, etc. In case of
         any consolidation or merger of the Corporation with or into another
         corporation or the conveyance of all or substantially all of the assets
         of the Corporation to another corporation, or any proposed
         reorganization or reclassification of the Corporation (except a
         transaction for which provision for adjustment is otherwise made in
         this Section 3), each share of Series A Preferred Stock, Series B
         Preferred Stock and Series C Preferred Stock shall thereafter be
         convertible into the number of shares of stock or other securities or
         property to which a holder of the number of shares of Common Stock of
         the Corporation deliverable upon conversion of such Series A Preferred
         Stock, Series B Preferred Stock and Series C Preferred Stock would have
         been entitled upon such consolidation, merger, conveyance,
         reorganization or reclassification; and, in any such case, appropriate
         adjustment (as determined in good faith by the Board of Directors)
         shall be made in the application of the provisions herein set forth
         with respect to the rights and interest thereafter of the holders of
         the Series A Preferred Stock, the holders of the Series B Preferred
         Stock and the holders of Series C Preferred Stock, to the end that the
         provisions set forth herein (including provisions with respect to
         changes in and other adjustments of the Conversion Prices) shall
         thereafter be applicable, as nearly as reasonably may be, in relation
         to any shares of stock or other property thereafter deliverable upon
         the conversion of the Series A Preferred Stock, Series B Preferred
         Stock and Series C Preferred Stock. The Company shall not effect any
         such consolidation, merger or sale unless prior to or simultaneously
         with the consummation thereof the successor corporation or purchaser,
         as the case may be, shall assume by written instrument the obligation
         to deliver to the holders of the Series A Preferred Stock, the holders
         of the Series B Preferred Stock and the holders of Series C Preferred
         Stock such shares of stock, securities or assets as, in accordance with
         the foregoing provisions, such holders are entitled to receive.

                  Upon the occurrence of any deemed liquidation, dissolution or
         winding up of the Corporation pursuant to Section 2(d) hereof, each
         holder of Series A Preferred Stock, each holder of Series B Preferred
         Stock and each holder of Series C Preferred Stock shall have the option
         of electing treatment of its shares of Series A Preferred Stock, Series
         B Preferred Stock and Series C Preferred Stock under this Section
         3(d)(vii) in lieu of Section 2(d) hereof,



                                       17
<PAGE>   19

         notice of which election shall be submitted in writing to the
         Corporation at its principal offices no later than five (5) business
         days before the effective date of such event.

         (e) No Impairment. The Corporation will not, by amendment of its
Certificate of Incorporation or through any reorganization, transfer of assets,
consolidation, merger, dissolution, issue or sale of securities or any other
voluntary action, avoid or seek to avoid the observance or performance of any of
the terms to be observed or performed hereunder by the Corporation but will at
all times in good faith assist in the carrying out of all the provisions of this
Section 3 and in the taking of all such action as may be necessary or
appropriate in order to protect the Conversion Rights of the holders of the
Series A Preferred Stock, the holders of the Series B Preferred Stock and the
holders of the Series C Preferred Stock against impairment.

         (f) Certificate as to Adjustments. Upon the occurrence of each
adjustment or readjustment of the Conversion Prices pursuant to this Section 3,
the Corporation at its expense shall promptly compute such adjustment or
readjustment in accordance with the terms hereof and furnish to each holder of
Series A Preferred Stock, each holder of Series B Preferred Stock and each
holder of Series C Preferred Stock a certificate setting forth such adjustment
or readjustment and showing in detail the facts upon which such adjustment or
readjustment is based. The Corporation shall, upon the written request at any
time of any holder of Series A Preferred Stock, any holder of Series B Preferred
Stock or any holder of Series C Preferred Stock, furnish or cause to be
furnished to such holder a like certificate setting forth (i) all such
adjustments and readjustments theretofore made, (ii) the Conversion Prices at
the time in effect, and (iii) the number of shares of Common Stock and the
amount, if any, of other property which at such time would be received upon the
conversion of Series A Preferred Stock, Series B Preferred Stock and Series C
Preferred Stock.

         (g) Notices of Record Date. In the event of any taking by the
Corporation of a record of the holders of any class of securities for the
purpose of determining the holders thereof who are entitled to receive any
dividend (other than a cash dividend which is in the same amount per share as
cash dividends paid in previous quarters) or other distribution, the Corporation
shall mail to each holder of Series A Preferred Stock, each holder of Series B
Preferred Stock and each holder of Series C Preferred Stock at least ten (10)
days prior to the date thereof, a notice specifying the date on which any such
record is to be taken for the purpose of such dividend or distribution.

         (h) Common Stock Reserved. The Corporation shall reserve and at all
times keep available out of its authorized but unissued Common Stock, free from
preemptive or other preferential rights, restrictions, reservations,
dedications, allocations, options, other warrants and other rights under any
stock option, conversion option or similar agreement, such number of shares of
Common Stock as shall from time to time be sufficient to effect conversion of
the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred
Stock.

         (i) No Reissuance of Series A Preferred Stock, Series B Preferred Stock
or Series C Preferred Stock. No shares of Series A Preferred Stock, Series B
Preferred Stock or Series C Preferred Stock which are converted into shares of
Common Stock as provided herein shall be reissued.



                                       18
<PAGE>   20

         (j) Issue Tax. The issuance of certificates for shares of Common Stock
upon conversion of Series A Preferred Stock, Series B Preferred Stock or Series
C Preferred Stock shall be made without charge to the holders thereof for any
issuance tax in respect thereof, provided that the Corporation shall not be
required to pay any tax which may be payable in respect of any transfer involved
in the issuance and delivery of any certificate in a name other than that of the
holder of the Series A Preferred Stock, the holder of the Series B Preferred
Stock or the holder of Series C Preferred Stock which is being converted.

         (k) Closing of Books. The Corporation will at no time close its
transfer books against the transfer of any shares of Series A Preferred Stock,
any shares of Series B Preferred Stock, any shares of Series C Preferred Stock
or any shares of Common Stock issued or issuable upon the conversion of any
shares of Series A Preferred Stock, Series B Preferred Stock or Series C
Preferred Stock in any manner which interferes with the timely conversion of
such Series A Preferred Stock, Series B Preferred Stock or Series C Preferred
Stock, except as may otherwise be required to comply with applicable securities
laws.

         (l) Definition of Common Stock. As used in this Section 3, the term
"Common Stock" shall mean and include the Corporation's authorized Common Stock,
par value $.01 per share, as constituted on the date of filing of this Amended
and Restated Certificate of Incorporation, and shall also include any capital
stock of any class of the Corporation thereafter authorized which shall neither
be limited to a fixed sum or percentage of par value in respect of the rights of
the holders thereof to participate in dividends nor entitled to a preference in
the distribution of assets upon the voluntary or involuntary liquidation,
dissolution or winding up of the Corporation; provided that the shares of Common
Stock receivable upon conversion of shares of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock shall include only shares
designated as Common Stock of the Corporation on the date of filing of this
Amended and Restated Certificate of Incorporation.


                                    SECTION 4

                                   REDEMPTION

         (a) Mandatory Redemption.

                  (i) If, on the fifth anniversary of the date of the Original
         Series A Issue Date (as defined in Section 3(d)(i) of Part B of this
         Article III) (such fifth anniversary being referred to herein as the
         "Fifth Anniversary Redemption Date"), there remain outstanding shares
         of Series A Preferred Stock, Series B Preferred Stock and/or Series C
         Preferred Stock, the holders of a majority of the then outstanding
         shares of Series A Preferred Stock, Series B Preferred Stock and Series
         C Preferred Stock (voting together as a separate class) may elect to
         have the Corporation redeem all (but not less than all) of the
         outstanding shares of Series A Preferred Stock, Series B Preferred
         Stock and Series C Preferred Stock at the Series A Redemption Price,
         Series B Redemption Price or Series C Stock Redemption Price (as the
         case may be) per share defined in paragraph (d) below, payable in cash
         in accordance with



                                       19
<PAGE>   21

         the schedule set forth in paragraph (ii) below; provided, however, that
         the Series C Preferred Stock shall be redeemed if, and only if, in
         addition to the vote of a majority of the holders of the Series A
         Preferred Stock, the Series B Preferred Stock and the Series C
         Preferred Stock (voting together as a separate class), the holders of a
         majority of outstanding shares of the Series C Preferred Stock (voting
         as a separate class) elect to have the Corporation redeem all, but only
         all, of the outstanding shares of Series C Preferred Stock. The
         election to redeem shares of Series A Preferred Stock, Series B
         Preferred Stock and Series C Preferred Stock under this paragraph (a)
         shall be made at least forty-five (45) days prior to the Fifth
         Anniversary Redemption Date.

                  (ii) Redemptions pursuant to this paragraph (a) shall be made
         in four (4) equal installments beginning on the Fifth Anniversary
         Redemption Date, and on each of the three (3) successive anniversaries
         of such date (each a "Subsequent Anniversary Redemption Date" and
         together with the Fifth Anniversary Redemption Date, the "Anniversary
         Redemption Dates"). The number of shares of Series A Preferred Stock
         required to be redeemed on any Anniversary Redemption Date shall be
         equal to the amount determined by dividing (x) the aggregate number of
         shares of Series A Preferred Stock outstanding immediately prior to the
         Anniversary Redemption Date by (y) the number of remaining Anniversary
         Redemption Dates (including the Anniversary Redemption Date to which
         such calculation applies). The number of shares of Series B Preferred
         Stock required to be redeemed on any Anniversary Redemption Date shall
         be equal to the amount determined by dividing (x) the aggregate number
         of shares of Series B Preferred Stock outstanding immediately prior to
         the Anniversary Redemption Date by (y) the number of remaining
         Anniversary Redemption Dates (including the Anniversary Redemption Date
         to which such calculation applies). The number of shares of Series C
         Preferred Stock required to be redeemed on any Anniversary Redemption
         Date shall be equal to the amount determined by dividing (x) the
         aggregate number of shares of Series C Preferred Stock outstanding
         immediately prior to the Anniversary Redemption Date by (y) the number
         of remaining Anniversary Redemption Dates (including the Anniversary
         Redemption Date to which such calculation applies).

                  (iii) If in any given year in which redemption is required
         sufficient funds are not legally available for such redemption on the
         applicable Anniversary Redemption Date to redeem all of the shares of
         Series A Preferred Stock, Series B Preferred Stock and Series C
         Preferred Stock then due to be redeemed, any redemption effected
         pursuant to this Section 4(a) shall be made as follows:

                           (1) the Corporation shall use a portion of such
                  available funds to redeem a number of shares of Series A
                  Preferred Stock equal to (x) the number of shares of Series A
                  Preferred Stock then due to be redeemed multiplied by (y) a
                  fraction, the numerator of which is the amount of funds
                  legally available for such redemption and the denominator of
                  which is the amount of funds that would be required to redeem
                  all of the shares of Series A Preferred Stock, Series B
                  Preferred Stock and Series C Preferred Stock then due to be
                  redeemed (such fraction, the "Reduction Ratio"), and


                                       20
<PAGE>   22

                           (2) the Corporation shall use the remainder of such
                  available funds to redeem a number of shares of Series B
                  Preferred Stock and Series C Preferred Stock equal to (x) the
                  number of shares of Series B Preferred Stock or Series C
                  Preferred Stock, as the case may be, then due to be redeemed
                  multiplied by (y) the Reduction Ratio.

                  (iv) Any redemption effected pursuant to this Section 4(a)
         shall be made on a pro rata basis among the holders of the Series A
         Preferred Stock based on the number of shares of Series A Preferred
         Stock then held by each of them. Any redemption effected pursuant to
         this Section 4(a) shall be made on a pro rata basis among the holders
         of the Series B Preferred Stock based on the number of shares of Series
         B Preferred Stock then held by each of them. Any redemption effected
         pursuant to this Section 4(a) shall be made on a pro rata basis among
         the holders of the Series C Preferred Stock based on the number of
         shares of Series C Preferred Stock then held by each of them.

         (b) Miscellaneous. Redemption shall only be permitted to the extent
that it is permitted under the General Corporation Law of Delaware. The
Corporation shall, to the fullest extent permitted by law, do all things
necessary to redeem the Series A Preferred Stock, Series B Preferred Stock and
Series C Preferred Stock and make the payments therefor pursuant to the terms of
this Section 4.

         (c) Available Funds. If in any given year in which redemption is
required sufficient funds are not legally available for such redemption on the
applicable Anniversary Redemption Date to redeem all of the shares of Series A
Preferred Stock, Series B Preferred Stock and Series C Preferred Stock then due
to be redeemed, any and all such unredeemed shares shall be carried forward and
redeemed together with other shares of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock which are due to be redeemed, at
such time and to the extent that funds of the Corporation are legally available
therefor. The shares of Series A Preferred Stock, Series B Preferred Stock and
Series C Preferred Stock which are subject to redemption but which have not been
redeemed and as to which the Series A Redemption Price, Series B Redemption
Price or Series C Preferred Stock (as the case may be) is not paid or set aside
due to insufficient legally available funds shall continue to be entitled to the
dividend, conversion and other rights, preferences and privileges of the Series
A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock until
such shares have been redeemed and the Series A Redemption Price, Series B
Redemption Price or Series C Preferred Stock (as the case may be) has been paid
or otherwise set aside with respect thereto.


                                       21
<PAGE>   23

         (d) Redemption Price. The price at which such shares of Series A
Preferred Stock shall be redeemed (the "Series A Redemption Price") shall be a
price equal to $5.62 per share, plus any dividends which, pursuant to Section 6
hereof, have accrued but remain unpaid at such time. The price at which shares
of Series B Preferred Stock shall be redeemed (the "Series B Redemption Price")
shall be a price equal to $12.07 per share, plus any dividends which, pursuant
to Section 6 hereof, have accrued but remain unpaid at such time. The price at
which such shares of Series C Preferred Stock shall be redeemed (the "Series C
Redemption Price") shall be $18.23 per share, plus any dividends which, pursuant
to Section 6 hereof, have accrued but remain unpaid at such time, provided that
for purposes of determining the Series C Redemption Price such accrued but
unpaid dividends shall be compounded annually.

         (e) Notice. Notice of any redemption shall be given by the Corporation
by certified or registered mail (return receipt requested), postage prepaid, by
personal delivery or overnight courier. Any notice given by the Corporation
shall be addressed to each holder at the address as it appears on the stock
transfer books of the Corporation and shall specify the applicable Anniversary
Redemption Date and the number of shares to be redeemed. On or after the
Anniversary Redemption Date as specified in any notice, the holder shall
surrender such holder's certificate for the number of shares to be redeemed as
stated in the notice to or from the Corporation. If less than all of the shares
represented by such certificates are redeemed, a new certificate shall forthwith
be issued for the unredeemed shares.

         (f) Conversion After Redemption. From and after an Anniversary
Redemption Date, no shares of the Series A Preferred Stock, Series B Preferred
Stock or Series C Preferred Stock to be redeemed on such Anniversary Redemption
Date shall be entitled to the conversion privileges set forth in Section 3
hereof.


                                    SECTION 5

                                  VOTING RIGHTS

         (a) Number of Votes. Except as otherwise required by law and the
provisions of this Section 5, the holders of Series A Preferred Stock, the
holders of Series B Preferred Stock, the holders of Series C Preferred Stock and
the holders of Common Stock shall be entitled to notice of any shareholders'
meeting and to vote together as a single class of capital stock upon any matter
submitted to a shareholder for a vote, on the following basis:

                  (i) Holders of Common Stock shall have one vote per share;

                  (ii) Holders of Series A Preferred Stock shall have that
         number of votes per share as is equal to the number of shares of Common
         Stock into which each such share of Series A Preferred Stock held by
         such holder is convertible at the time of such vote;

                  (iii) Holders of Series B Preferred Stock shall have that
         number of votes per share as is equal to the number of shares of Common
         Stock into which each such share of Series



                                       22
<PAGE>   24

         B Preferred Stock held by such holder is convertible at the time of
         such vote;

                  (iv) Holders of Series C Preferred Stock shall have that
         number of votes per share as is equal to the number of shares of Common
         Stock into which each such share of Series C Preferred Stock held by
         such holder is convertible at the time of such vote

         (b) Election of Directors. The Board of Directors shall consist of not
less than six (6) nor more than nine (9) without the approval or written consent
of the holders of a majority of the outstanding shares of Series A Preferred
Stock, Series B Preferred Stock and Series C Preferred Stock (voting together as
a separate class). Except as otherwise required by law, and subject to the terms
of the Amended and Restated Shareholders' Agreement dated February 23, 2000, by
and among the Corporation and certain of its shareholders, as the same may be
amended, the holders of Series A Preferred Stock, the holders of Series B
Preferred Stock, the holders of Series C Preferred Stock and the holders of
Common Stock shall be entitled to vote upon the election of directors on the
following basis:

                  (i) so long as at least 215,385 shares of Series A Preferred
         Stock or at least 73,149 shares of Series B Preferred Stock remain
         issued and outstanding, the holders of Common Stock then issued and
         outstanding, voting separately as a class, shall, by majority vote,
         elect two (2) members of the Board of Directors;

                  (ii) (1) so long as at least 355,385 shares of Series A
         Preferred Stock remain issued and outstanding, the holders of Series A
         Preferred Stock then issued and outstanding, voting separately as a
         class, shall, by majority vote, elect two (2) members of the Board of
         Directors, or (2) if less than 355,385 but more than 215,385 shares of
         Series A Preferred Stock remain issued and outstanding, the holders of
         Series A Preferred Stock then issued and outstanding, voting separately
         as a class, shall, by majority vote, elect one (1) member of the Board
         of Directors;

                  (iii) so long as at least 73,149 shares of Series B Preferred
         Stock remain issued and outstanding, the holders of Series B Preferred
         Stock then issued and outstanding, voting separately as a class, shall,
         by majority vote, elect one (1) member of the Board of Directors (who
         shall be reasonably acceptable to the Company, provided that Barclay A.
         Phillips shall be deemed acceptable to the Company);

                  (iv) the holders of Series A Preferred Stock and the holders
         of Series B Preferred Stock, and the holders of Common Stock then
         issued and outstanding, voting together as a single class (in the
         manner set forth in paragraph (a) above) shall, by majority vote, elect
         one (1) member of the Board of Directors who will add strategic
         business and industry value to the Company and who is mutually
         acceptable to the Company and the holders of a majority of the Series B
         Preferred;

                  (v) the holders of Common Stock then issued and outstanding,
         voting together as a single class (in the manner set forth in paragraph
         (a) above) with (1) the holders of Series A Preferred Stock (so long as
         at least 215,385 shares of Series A Preferred Stock



                                       23
<PAGE>   25

         remain issued and outstanding), (2) the holders of Series B Preferred
         Stock (so long as at least 73,149 shares of Series B Preferred Stock
         remain issued and outstanding) and (3) the holders of Series C
         Preferred Stock (so long as at least 173,250 shares of Series C
         Preferred Stock remain issued and outstanding) shall, by majority vote,
         elect any members of the Board of Directors not elected as provided in
         paragraphs (i), (ii), (iii) and (iv) above; and

                  (vi) if fewer than 215,385 shares of Series A Preferred Stock
         remain issued and outstanding and fewer than 73,149 shares of Series B
         Preferred Stock remain issued and outstanding and fewer than 173,250
         shares of Series C Preferred Stock remain issued and outstanding, the
         holders of Series A Preferred Stock, the holders of Series B Preferred
         Stock, the holders of the Series C Preferred Stock and the holders of
         Common Stock then issued and outstanding, voting together as a single
         class (in the manner set forth in paragraph (a) above) shall, by
         majority vote, elect the entire Board of Directors.

         (c) Quorums. Except as otherwise required by law, the following shall
constitute quorums at meetings of shareholders:

                  (i) The presence in person, by teleconference or by proxy of
         the holders of shares constituting a majority of the votes entitled to
         vote thereat, calculated in accordance with Section 5(a) hereof, shall
         constitute a quorum for the purpose of transaction of business at all
         meetings of shareholders, except with respect to election of directors
         under Section 5(b) hereof; and

                  (ii) For the purpose of electing directors, (A) the presence
         in person, by teleconference or by proxy of the holders of a majority
         of the shares of Series A Preferred Stock entitled to vote thereat
         shall constitute a quorum for the purpose of electing that number of
         directors of the Board of Directors which such shareholders are
         entitled to elect; (B) the presence in person, by teleconference or by
         proxy of the holders of a majority of the shares of Series B Preferred
         Stock entitled to vote thereat shall constitute a quorum for the
         purpose of electing that number of directors of the Board of Directors
         which such shareholders are entitled to elect; and (C) the presence in
         person or by proxy of the holders of a majority of the shares of Common
         Stock, Series A Preferred Stock, Series B Preferred Stock and Series C
         Preferred Stock entitled to vote thereat shall constitute a quorum for
         the purpose of electing that number of directors of the Board of
         Directors which such shareholders are entitled to elect.


                                    SECTION 6

                                 DIVIDEND RIGHTS

         Each holder of shares of Series A Preferred Stock, each holder of
shares of Series B Preferred Stock and each holder of Series C Preferred Stock
shall be entitled to receive, for each share of Series A Preferred Stock, Series
B Preferred Stock and Series C Preferred Stock registered in his, her or its
name on the stock transfer books of the Corporation, annual




                                       24
<PAGE>   26

dividends at rates equal to forty-five cents ($0.45) per annum per share of
Series A Preferred Stock (the "Series A Dividend Rate"), ninety-seven cents
($0.97) per annum per share of Series B Preferred Stock (the "Series B Dividend
Rate"), and one dollar and forty six cents ($1.46) per annum per share of Series
C Preferred Stock (the "Series C Dividend Rate"). Dividends on Series A
Preferred Stock, Series B Preferred Stock and Series C Preferred Stock shall
accrue on each share beginning on the date of issuance, shall be payable each
January 1 for the twelve (12) months or, in the case of the year in which such
share is issued or the year in which such share is redeemed or converted,
portion of the twelve (12) months, then ended, and shall be cumulative.
Dividends payable on the Series A Preferred Stock, Series B Preferred Stock and
Series C Preferred Stock may, at the Corporation's option, be paid either in
cash or in fully-paid and non-assessable shares of Common Stock; provided that
no dividends on the Series A Preferred Stock, the Series B Preferred Stock or
the Series C Preferred Stock may be paid in cash unless all dividends (or equal
percentages thereof) paid on both the Series A Preferred Stock, the Series B
Preferred Stock and the Series C Preferred Stock are paid in cash. If the
Company elects to pay dividends on the Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock in Common Stock, each share of
Common Stock issued in payment of such dividends shall be deemed to have a value
equal to the then Fair Market Value of a share of Common Stock (as defined
below). The Corporation warrants that all Common Stock issued in such manner
will be duly authorized and issued and fully paid and non-assessable upon issue
by the Corporation and free from original issue taxes. Any payment made by the
Corporation on the unpaid cumulative dividends, if less than the total amount of
such dividends, shall be applied first to those dividends which have been
accrued for the longest time.

         The "Fair Market Value" of one share of Common Stock shall be deemed to
be the average of the daily closing prices for the thirty (30) consecutive
trading days ending no more than fifteen (15) trading days before the date of
computation (as adjusted for any stock dividend, split, combination or
reclassification that took effect during such thirty (30) day period). The
closing price for each day (the "Closing Price") shall be the last reported
sales price regular way or, in case no such reported sales took place on such
day, the average of the last reported bid and asked prices regular way, in
either case on the principal national securities exchange on which the Common
Stock is listed or admitted to trading (or if the Common Stock is not at the
time listed or admitted for trading on any such exchange, then such price as
shall be equal to the average of the last reported bid and asked prices, as
reported by the Nasdaq Small Capitalization Market (the "Small Cap Market") or
the Nasdaq National Market ("Nasdaq") on such day, or if, on any day in
question, the Common Stock shall not be quoted on the Small Cap Market or the
Nasdaq, then such price shall be equal to the average of the last reported bid
and asked prices on such day as reported by The National Quotation Bureau
Incorporated or any similar reputable quotation and reporting service, if such
quotation is not reported by The National Quotation Bureau Incorporated);
provided, however, that if the Common Stock is not traded in such manner that
the quotations referred to in this Section 6 are available for the period
required hereunder, the Fair Market Value shall be determined in good faith by
the Board of Directors of the Company or, if such determination cannot be made,
by a recognized independent investment banking firm selected by the Board of
Directors of the Company (or if such selection cannot



                                       25
<PAGE>   27

be made, by a recognized independent investing banking firm selected by the
American Arbitration Association in accordance with its rules), and provided,
further, that in no event shall the Fair Market Value as of any date be deemed
to be more than the fair market value as last determined by the Board of
Directors for purposes of issuing stock options under any Plan.

         No dividend or other distribution shall be paid on or declared or set
apart for payment on any shares of the Common Stock of the Corporation or any
shares of any class or series or issue of Preferred Stock as long as any
dividends payable on the Series A Preferred Stock, Series B Preferred Stock and
Series C Preferred Stock are in arrears, unless the holders of at least a
majority of the then outstanding shares of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock (voting together as a separate
class) consent to such dividend or distribution.

         The term "distribution" as used in this Section 6 and in Section 7
hereof shall include the transfer of cash or property without consideration,
whether by way of dividend or otherwise (except a dividend in shares of Common
Stock), or the purchase or redemption of shares of the Corporation (other than
from employees of the Corporation upon termination of employment or pursuant to
the Corporation's rights of first refusal, in each case upon approval of the
Board of Directors), for cash or property, including such transfer, purchase or
redemption by a subsidiary of the Corporation. The time of any distribution by
way of dividends shall be the date of declaration thereof, and the time of any
distribution by purchase or redemption of shares shall be the date on which cash
or property is transferred by the Corporation, whether or not pursuant to a
contract of an earlier date; provided that where a debt security is issued in
exchange for shares, the time of the distribution is the date when the
Corporation acquires the shares for such exchange.


                                    SECTION 7

                                    COVENANTS

         Without limiting the rights of the holders of the Series A Preferred
Stock, the holders of the Series B Preferred Stock or the holders of Series C
Preferred Stock to each vote as separate classes or together as a single class,
as required by law or as otherwise provided under this Amended and Restated
Certificate of Incorporation, so long as any shares of Series A Preferred Stock,
Series B Preferred Stock or Series C Preferred Stock shall be outstanding, the
Corporation shall not, without first obtaining the affirmative vote or written
consent of the holders of not less than two-thirds (2/3's) of such outstanding
shares of Series A Preferred Stock, Series B Preferred Stock and Series C
Preferred Stock (voting together as a separate class):

                  (a) amend or repeal any provision of, or add any provision to,
         this Amended and Restated Certificate of Incorporation or the
         Corporation's Bylaws which adversely affects the holders of the Series
         A Preferred Stock, the holders of the Series B Preferred Stock or the



                                       26
<PAGE>   28

         holders of the Series C Preferred Stock or any right, preference or
         privilege of such holders; provided, however, that any amendment or
         repeal of this Amended and Restated Certificate of Incorporation or the
         Corporation's Bylaws which adversely affects the holders of the Series
         C Preferred Stock shall require the affirmative vote or written consent
         of at least a majority of the outstanding shares of the Series C
         Preferred Stock (voting as a separate class);

                  (b) reclassify any Common Stock into shares having any
         preference or priority as to dividends or assets or other rights and
         privileges in any case superior to or on a parity with any such
         preference, priority, right or privilege of the Series A Preferred
         Stock, Series B Preferred Stock or Series C Preferred Stock (including,
         without limitation, by granting to the holder of any security issued by
         the Corporation a security interest or lien on assets of the
         Corporation); provided, however, that any such reclassification which
         results in such reclassified shares having any rights or preferences
         superior to or on parity with the Series C Preferred Stock shall
         require the affirmative vote or written consent of at least a majority
         of the outstanding shares of the Series C Preferred Stock (voting as a
         separate class); or otherwise effect a capital reorganization of either
         the Corporation or any subsidiary of the Corporation, or effect a
         liquidation or dissolution of the Corporation;

                  (c) apply any of its assets to the redemption, retirement,
         purchase or other acquisition directly or indirectly, through
         subsidiaries or otherwise, of any shares of Common Stock or other
         securities of the Corporation (other than the Series A Preferred Stock,
         the Series B Preferred Stock and the Series C Preferred Stock in
         accordance with the provisions of Section 4 hereof), except from
         employees of the Corporation upon termination of employment or pursuant
         to the Corporation's rights of first refusal;

                  (d) consolidate or merge the Corporation or any subsidiary of
         the Corporation into or with, or acquire or cause any subsidiary of the
         Corporation to acquire the stock or all or substantially all the assets
         of, any other corporation, partnership or other entity;

                  (e) sell, lease, convey, encumber or otherwise dispose of all
         or substantially all of the property or business of the Corporation or
         any subsidiary of the Corporation or effect a voluntary dissolution or
         liquidation of the Corporation;

                  (f) create, authorize or issue, directly or indirectly,
         capital stock or other securities, having any preference or priority as
         to dividends or assets, or other rights or privileges, in any case
         superior to or on a parity with any such preference, priority, right or
         privilege of the Series A Preferred Stock, the Series B Preferred Stock
         or the Series C Preferred Stock (including, without limitation, by
         granting to the holder of any security issued by the Corporation a
         security interest or lien on assets of the Corporation); provided,
         however, that any such creation, authorization or issuance of capital
         stock or securities having any rights or preferences superior to or on
         parity with the Series C Preferred Stock shall require the affirmative
         vote or written consent of at least a majority of the outstanding
         shares of the Series C Preferred Stock (voting as a separate class);


                                       27
<PAGE>   29

                  (g) increase or decrease the authorized number of shares of
         Preferred Stock; provided, however, any increase or decrease in the
         authorized number of shares of Series C Preferred Stock shall require
         the affirmative vote or written consent of at least a majority of the
         outstanding shares of the Series C Preferred Stock (voting as a
         separate class);

                  (h) pay, set aside for payment or declare any dividend or
         other distribution (as defined in Section 6 hereof) on any share of
         Common Stock or any shares of any class of Preferred Stock (other than
         Series A Preferred Stock, Series B Preferred Stock and Series C
         Preferred Stock), unless all dividends accumulated on the Series A
         Preferred Stock, Series B Preferred Stock and Series C Preferred Stock
         shall have been either paid in full or funds set aside for the payment
         thereof in accordance with the provisions of Section 6 hereof;

                  (i) change the nature of the Corporation's business in any
         material way or make any material change to the Corporation's business
         plan, as approved by the holders of at least two-thirds (2/3's) of the
         outstanding shares of Series A Preferred Stock, Series B Preferred
         Stock and Series C Preferred Stock (voting together as a separate
         class);

                  (j) issue any shares of Common Stock, provided that the
         Corporation, upon approval of the Board of Directors, may issue shares
         of Common Stock issuable upon occurrence of the events described in, or
         in connection with the circumstances set forth in, subclauses (A), (B),
         (C) and (E) of Section 3(d)(i)(6) hereof; or

                  (k) increase the size of the Board of Directors to more than
         nine (9) directors or decrease the size of the Board of Directors to
         fewer than six (6) directors.


                                    SECTION 8

                      STOCK DIVIDENDS, STOCK DISTRIBUTIONS,
                  SUBDIVISIONS, COMBINATIONS AND CONSOLIDATIONS

         In the event the Corporation shall issue additional shares of Series A
Preferred Stock, Series B Preferred Stock or Series C Preferred Stock in a stock
dividend, other stock distribution or subdivision, or in the event the
outstanding shares of Series A Preferred Stock, Series B Preferred Stock or
Series C Preferred Stock shall be combined or consolidated, by reclassification
or otherwise, into a lesser number of shares of Series A Preferred Stock, Series
B Preferred Stock or Series C Preferred Stock, (i) the amounts set forth in
Section 2(a) hereof, (ii) the Series A Automatic Conversion Price, the Series B
Automatic Conversion Price and the Series C Automatic Conversion Price (each as
defined in Section 3(b) hereof), (iii) the amounts set forth in Section 4(d)
hereof, (iv) the number of shares of Series A Preferred Stock, Series B
Preferred Stock and Series C Preferred Stock specified in Section 5(b) and
Section 7, and (v) the Series A Dividend Rate, Series B Dividend Rate and Series
C Dividend Rate set forth in Section 6 hereof, in each case in effect
immediately prior to such event shall, concurrently therewith, be
proportionately decreased



                                       28
<PAGE>   30

(in the case of a stock dividend, other stock distribution or subdivision) or
increased (in the case of a combination or consolidation) in each such case to
adjust equitably therefor.


                                    SECTION 9

                                 RESIDUAL RIGHTS

         All rights accruing to the outstanding shares of capital stock of the
Corporation not expressly provided for to the contrary herein shall be vested in
the Common Stock.


                                   ARTICLE IV

                               BOARD OF DIRECTORS


                                    SECTION 1

                                   MANAGEMENT

         The business and affairs of the Corporation shall be managed by the
board of directors. The board of directors shall meet at least once during every
calendar quarter. A two-thirds (2/3's) affirmative vote of the board of
directors shall be required to approve each annual budget and operating plan of
the Corporation.


                                    SECTION 2

                                    NO BALLOT

         The directors need not be elected by written ballot unless the bylaws
of the Corporation shall so provide.

                                    SECTION 3

                          INDEMNIFICATION AND LIABILITY

         To the fullest extent permitted by Delaware General Corporation Law as
the same exists or may hereafter be amended, each officer and director of this
Corporation shall be indemnified by the Corporation and shall not be personally
liable to the Corporation or its stockholders for monetary damages for breach of
fiduciary duty as a director or officer.



                                       29
<PAGE>   31

                                    ARTICLE V

                            MEETINGS OF STOCKHOLDERS

         Meetings of the stockholders may be held within or without the State of
Delaware, as the bylaws may provide. The books of the Corporation may be kept
(subject to any provision contained in the Delaware statutes) outside the State
of Delaware at such place or places as may be designated from time to time by
the board of directors or in the Bylaws of the Corporation.


                                   ARTICLE VI

                                     BYLAWS

         In furtherance and not in limitation of the powers conferred by the
laws of the State of Delaware, the board of directors is expressly authorized to
adopt, amend or repeal the Bylaws of the Corporation.


                                   ARTICLE VII

                               PERPETUAL EXISTENCE

         The Corporation is to have perpetual existence.




                                       30
<PAGE>   32

                                  ARTICLE VIII

                            COMPROMISE OR ARRANGEMENT

         Whenever a compromise or arrangement is proposed between the
Corporation and its creditors or any class of them and/or between this
Corporation and its stockholders or any class of them, any court of equitable
jurisdiction within the State of Delaware may, on the application in a summary
way of this Corporation or of any creditor or stockholder thereof or on the
application of any receiver or receivers appointed for this Corporation under
the provisions of section 291 of Title 8 of the Delaware Code or on the
application of trustees in dissolution or of any receiver or receivers appointed
for this Corporation under the provisions of section 279 of Title 8 of the
Delaware Code order a meeting of the creditors or class of creditors, and/or of
the stockholders or class of stockholders of this Corporation, as the case may
be, to be summoned in such matter as the said court directs. If a majority in
number representing three-fourths in value of the creditors or class of
creditors, and/or of the stockholders or class of stockholders of this
Corporation, as the case may be, agree to any compromise or arrangement and to
any reorganization of this Corporation as a consequence of such compromise or
arrangement, the said compromise or arrangement and the said reorganization
shall, if sanctioned by the court to which the said application has been made,
be binding on all the creditors or class of creditors, and/or on all the
stockholders or class of stockholders, of this Corporation, as the case may be,
and also on this Corporation.

                                   ARTICLE IX

                              AMENDMENTS AND REPEAL

         Subject to any limitations contained in this Amended and Restated
Certificate of Incorporation (including, without limitation, those contained in
Section 7 of Part B of Article III), the Corporation reserves the right to
amend, alter, change, or repeal any provision contained in this Amended and
Restated Certificate of Incorporation, in the manner now or hereafter prescribed
by the laws of the State of Delaware, and all rights herein conferred are
granted subject to this reservation.

         This Amended and Restated Certificate of Incorporation has been duly
adopted by vote of the stockholders in accordance with the provisions of
Sections 242, 245 and 211 of the General Corporation Law of Delaware, as
amended.

         IN WITNESS WHEREOF, CELLOMICS, INC., has caused this certificate to be
signed by its President as of this ____ day of September ________, 2000.

                                    CELLOMICS, INC.

                                    By: __________________________________
                                        Name:  D. Lansing Taylor
                                        Title: Chief Executive Officer and
                                               President



                                       31


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