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<PAGE> 1 EXHIBIT 23.1 CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS We consent to the references to our firm under the captions "Selected Financial Data" and "Experts" and to the use of our report dated May 29, 2000 in Amendment No. 2 to the Registration Statement (Form S-1) and related prospectus of Arena Pharmaceuticals, Inc. for the registration of shares of its common stock. /s/ ERNST & YOUNG LLP July 14, 2000
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