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EXHIBIT 16.1
[PRICEWATERHOUSECOOPERS LLP LETTERHEAD]
October 23, 2000
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549
Commissioners:
We have read the statements made by BioMedicines, Inc. (copy attached), which
we understand will be filed with the Commission as part of the Company's
Registration Statement on Form S-1. We agree with the statements concerning
our Firm in such Form S-1 under the caption "change in independent auditors."
Very truly yours,
/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP
