NUVEEN UNIT TRUSTS SERIES 81
487, 2000-02-17
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<PAGE>

                                                     File No. 333-95751
                                                     1940 Act File No. 811-08103


                       Securities and Exchange Commission
                            Washington, D.C. 20549
                                Amendment No. 1
                                      To
                                   Form S-6

For Registration under the Securities Act of 1933 of Securities of Unit
Investment Trusts Registered on Form N-8B-2

A.  Exact name of Trust:  Nuveen Unit Trusts, Series 81

B.  Name of Depositor:    John Nuveen & Co. Incorporated

C.  Complete address of Depositor's principal executive offices:

                              333 West Wacker Drive
                              Chicago, Illinois 60606

D.  Name and complete address of agents for service:

                              John Nuveen & Co. Incorporated
                              Attention: Alan G. Berkshire
                              333 West Wacker Drive
                              Chicago, Illinois 60606

                              Chapman and Cutler
                              Attention: Eric F. Fess
                              111 West Monroe Street
                              Chicago, Illinois 60603

It is proposed that this filing will become effective (check appropriate box)

- ----
:  :  immediately upon filing pursuant to paragraph (b)
- ----
:  :  on (date) pursuant to paragraph (b)
- ----
:  :  60 days after filing pursuant to paragraph (a)
- ----
:  :  on (date) pursuant to paragraph (a) of rule 485 or 486
- ----

E.    Title of securities being registered: Units of fractional undivided
      beneficial interest.

F.    Approximate date of proposed sale to the public: As soon as practicable
      after the effective date of the Registration Statement.

- ----
:X :  Check box if it is proposed that this filing will become effective on
- ----  February 17, 2000 at 1:30 p.m. pursuant to Rule 487.
<PAGE>





                                 [NUVEEN LOGO]

Nuveen Unit Trusts, Series 81

Nuveen--Dow Jones Global Titans Index/SM/ Portfolio,

February 2000

Nuveen Nasdaq 100 Index Portfolio,

February 2000

    Prospectus Part A dated February 17, 2000

 .Portfolios Invest in Stocks Included in the Indices

 .Portfolios Seek Capital Appreciation
 .Reinvestment Option
 .Letter of Intent Available

The Securities and Exchange Commission has not approved or disapproved these
securities or passed upon the adequacy of this Prospectus. Any representation
to the contrary is a criminal offense.
                                      ---

INX-02-00-P                            1
<PAGE>

                                              CUSIP Nos:

Nuveen Unit Trusts, Series 81

                                              Dividend
                                              in cash     Reinvested  Wrap
Nuveen--Dow Jones Global Titans Index/SM/
Portfolio, February 2000                      67066R142   67066R159   67066R167
Nuveen Nasdaq 100 Index Portfolio,
February 2000                                 670922152   670922160   670922178


Overview

Nuveen Unit Trusts, Series 81 in-cludes the unit investment trusts listed above.
The Portfolios seek to provide capital appreciation by in-vesting in the common
stocks in-cluded in the respective indices.

The securities held by the Portfo-lios will be periodically adjusted to
generally reflect the current se-lections and weightings of the indi-ces. The
Portfolios are scheduled to terminate in approximately five years.

Contents

2  Overview
3  Nuveen--Dow Jones Global Titans
   Index/SM/ Portfolio, February 2000
3  Risk/Return Summary
3  Investment Objective
3  Investment Strategy
3  Security Selection
3  Dow Jones Global Titans Index/SM/
4  Industry Diversification
4  Primary Risks
4  Investor Suitability
4  Fees and Expenses
6  Schedule of Investments
8  Nuveen Nasdaq 100 Index
   Portfolio, February 2000
8  Risk/Return Summary
8  Investment Objective
8  Investment Strateg
8  Security Selection
8  The Nasdaq 100 Index
8  Industry Diversification
8  Primary Risks
9  Investor Suitability
9  Fees and Expenses
11 Schedule of Investments
13 How to Buy and Sell Units
13 Investing in a Portfolio
13 Sales or Redemptions
13 Risk Factors
15 Distributions
15 Income Distributions
15 Capital Distributions
15 General Information
15 Termination
15 The Sponsor
16 Dealer Concessions
16 Optional Features
16 Letter of Intent
16 Reinvestment
16 Nuveen Mutual Funds
17 Notes to Portfolios
18 Statements of Condition
19 Report of Independent Public
   Accountants

For the Table of Contents of Part B, see Part B of the Prospectus.
- -------

Units are not deposits or obliga-tions of, or guaranteed by any bank. Units are
not FDIC insured and involve investment risk, in-cluding the possible loss of
principal.


"Dow Jones Industrial Average/SM/", The Dow 5/SM/, The Dow 10/SM/, "DJIA/SM/"
and Dow Jones Global Titans Index/SM/ are service marks of Dow Jones & Company,
Inc. ("Dow Jones") and have been licensed for use for certain purposes by John
Nuveen & Co. Incorporated ("Nuveen" or the "Sponsor") on behalf of the Nuveen-
Dow Jones Global Titan Index/SM/ Portfolio (the "Global Titans Portfolio"). The
Portfolio is not endorsed, sold or promoted by Dow Jones, and Dow Jones makes no
representation regarding the advisability of investing in the Portfolio.

The Nasdaq 100(R), Nasdaq 100 Index(R), and Nasdaq(R) are trade or service
marks of The Nasdaq Stock Market, Inc. (which with its affiliates are the Cor-
porations) and are licensed for use by Nuveen. The Nuveen Nasdaq 100 Index
Portfolio (the "Nasdaq 100 Portfolio") has not been passed on by the Corpora-
tions as to its legality or suitability. The Nasdaq 100 Portfolio is not is-
sued, endorsed, sold, or promoted by the Corporations. THE CORPORATIONS MAKE NO
WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE NASDAQ 100 INDEX OR THE
NASDAQ 100 PORTFOLIO.

                                      ---
                                       2
<PAGE>


Nuveen--Dow Jones Global Titans IndexSM Portfolio, February 2000

Risk/Return Summary

Investment Objective

The Portfolio seeks to provide capital appreciation.

Investment Strategy

The Portfolio consists of the securities included in the Dow Jones Global Ti-
tans Index. The securities held by the Portfolio will be periodically adjusted
to generally replicate the current selections and weightings of the Dow Jones
Global Titans Index.

Security Selection

We select the securities for the Portfolio in the following manner:

 . On the Initial Date of Deposit, the Portfolio consists of each of the stocks
  included in the Dow Jones Global Titans Index.

 . During an initial adjustment period that will not exceed 30 days, the Port-
  folio will be modified to duplicate, to the extent practicable, the stocks
  contained in the index and their weightings.

 . Following the initial adjustment period, it is expected that:

 --The Portfolio will continue to be invested in substantially all (at least
  95%) of the stocks in the index; and

 --The Sponsor will attempt to maintain a correlation between the Portfolio's
  holdings and the index of .97 to .99 over the term of the Portfolio. Howev-
  er, the performance of the Portfolio may not mirror the performance of the
  index.

 . Adjustments to the Portfolio's holdings will be made on an ongoing basis
  when:

 --The Portfolio invests in new securities to create new Units;

 --Issues are removed from or added to the index;

 --Securities are sold to meet redemptions, to pay sales charges and ex-
  penses, or for tax reasons; or

 --It is necessary to maintain the correlation between the Portfolio and the
  index.

See "Composition of Trusts," "The Portfolios," and "Investment Supervision" in
Part B of the Prospectus for details.

With the foreign securities included in the Portfolio, the Portfolio may hold
either the stocks of the foreign companies or American Depositary Receipts
("ADRs") of those companies. See "Risk Factors" for a discussion of ADRs and
the risks associated with foreign securities.

Dow Jones Global Titans IndexSM

The Dow Jones Global Titans Index is composed of 50 of some of the world's
most well known and well established blue-chip companies, and provides consid-
erable exposure to global markets.

The major characteristics and key benefits of the companies included in the
Dow Jones Global Titans Index can be summarized into the following points:

  .Market leadership;

  .Multinational exposure;

  .Global diversification;

  .High liquidity;

  .Low turnover;

  .Sufficient market coverage; and

  .Competitive performance.

See "The Dow Jones Global Titans Index" in Part B of the Prospectus for addi-
tional information regarding the index.

                                      ---
                                       3
<PAGE>

Industry Diversification

Based upon the principal business of each issuer and current market values,
the index, as of February 9, 2000, represented the following industries:

<TABLE>
<CAPTION>
                                  Approximate
Industry                        Index Percentage
- --------                        ----------------
<S>                             <C>
Aerospace/Defense                     0.57%
Auto--Cars/Light Trucks               5.30%
Beverages--Non-alcoholic              2.20%
Chemicals--Diversified                1.14%
Computer Software                     8.37%
Computers--Micro                      5.28%
Cosmetics & Toiletries                1.92%
Diversified Financial Services        4.89%
Diversified Manufacturing             8.52%
Food--Misc/Diversified                1.39%
Medical Products                      1.73%
Medical--Drugs                        5.30%
Money Center Banks                    7.20%
Multi-line Insurance                  4.40%
Multimedia                            1.21%
Oil Companies--Integrated             9.61%
Retail--Discount                      3.98%
Semiconductors                        5.45%
Telecommunications Equipment          2.58%
Telephone--Integrated                13.41%
Telephone--Local                      2.69%
Telephone--Long Distance              2.13%
Tobacco                               0.73%
                                     ------
Total                                  100%
</TABLE>

Primary Risks

You can lose money by investing in the Portfolio. In addition, the Portfolio
may not perform as well as you hope. These things can happen for various rea-
sons, including:

 . Stock prices can be volatile.

 . Share prices or dividend rates on the stocks may decline during the life of
  the Portfolio.

 . The Portfolio is not actively managed and may continue to purchase or hold a
  stock included in the index even though the stock's outlook or its market
  value or yield may have changed.

 . The Portfolio will contain stocks of foreign companies. The Portfolio's in-
  vestment in foreign stock presents additional risk, including currency risk.
  Foreign companies may be affected by adverse political, diplomatic and eco-
  nomic developments; changes in foreign currency exchange rates; taxes; less
  publicly available information; greater price volatility; less liquidity and
  other factors.

 . The performance of the Portfolio may not sufficiently correspond with the
  performance of the index. This is due to a variety of factors that include:

 --the impracticability of owning each of the securities in the index with
  the exact weightings at any given time;

 --the possibility of tracking errors;

 --the time that elapses between a change in the index and a change in the
  Portfolio; and

 --sales charges and expenses.

Investor Suitability

The Portfolio may be suitable for you if:

 . You are seeking to own the components of the Dow Jones Global Titans Index
  in one convenient package;

 . You want capital appreciation potential; and

 . The Portfolio represents only a portion of your overall investment portfo-
  lio.

The Portfolio is not appropriate for you if:

 . You are unwilling to take the risks involved with owning an unmanaged index-
  based equity investment;

 . You are seeking preservation of capital or high current income; or

 . You do not have a long-term investment horizon.

Fees and Expenses

This table shows the fees and expenses you may pay, directly or indirectly,
when you invest in the Portfolio.
<TABLE>
<CAPTION>
                                                                    Approximate
                                                    Amount per Unit % of Public
                                                     (based on $10   Offering
                                                         Unit)       Price (1)
                                                    --------------- -----------
<S>                                                 <C>             <C>
Sales Charge
Maximum Sales Charge (Deferred)(2).................     $ 0.450        4.50%(2)

Estimated Annual Operating Expenses

Trustee's Fee......................................     $0.0185       0.185%
Sponsor's Supervisory Fee..........................     $0.0035       0.035%
Bookkeeping and Administrative Fees................     $0.0025       0.025%
Evaluator's Fees...................................     $0.0030       0.030%
Other Operating Expenses(3)........................     $0.0068       0.068%
                                                        -------       ------
Total..............................................     $0.0343       0.343%
Maximum Organization Costs(4)......................     $0.0225       0.225%
</TABLE>

                                      ---
                                       4
<PAGE>

- ---------

(1) Based on 100 Units with a $10 per Unit Public Offering Price as of the
    Initial Date of Deposit.

(2) The maximum sales charge is a fixed dollar amount of $0.45 per Unit, how-
    ever, the maximum sales charge may not exceed 5.5% of the Public Offering
    Price. The entire sales charge is deferred for investors who purchase
    Units prior to the first deferred sales charge deduction (see below).

(3) Other Operating Expenses include annual licensing fees paid to cover a li-
    cense to use service marks, trademarks and trade names of Dow Jones but do
    not include brokerage costs and other transactional fees.

(4) Organization costs are deducted from Portfolio assets at the earlier of
    the close of the initial offering period or 6 months after Initial Date of
    Deposit.

The entire sales charge is deferred and deducted monthly in installments of
$0.09 per Unit from September 29, 2000 through January 31, 2001. However, for
Units purchased after the beginning of the deferred sales charge period you
will pay an up-front sales charge equal to the deferred sales charges already
collected. The maximum sales charge will not exceed 5.5% of the Public Offer-
ing Price of the Units.

The maximum per Unit sales charges are reduced as follows:

<TABLE>
<CAPTION>
                                                               Your maximum
If you buy the following number of Units:*                 sales charge will be:
- ---------------------------------------------------------- ---------------------
<S>                                                        <C>
Less than 5,000...........................................        $0.450
5,000 to 9,999............................................        $0.425
10,000 to 24,999..........................................        $0.400
25,000 to 49,999..........................................        $0.350
50,000 to 99,999..........................................        $0.250
100,000 or more...........................................        $0.150
</TABLE>

 * Sales charge reductions are computed both on a dollar basis and on the ba-
   sis of the number of Units purchased, using the equivalent of 5,000 Units
   to $50,000, 10,000 Units to $100,000 etc., and will be applied on that ba-
   sis which is more favorable to you.

As described in "Public Offering Price" in Part B of the Prospectus, certain
classes of investors are also entitled to reduced sales charges.

Example

This example may help you compare the cost of investing in the Portfolio to
the cost of investing in other funds.

The example assumes that you invest $10,000 in the Portfolio for the periods
indicated and then either redeem or do not redeem your Units at the end of
those periods. The example also assumes a 5% return on your investment each
year and that the Portfolio's operating expenses stay the same. The example
does not include brokerage costs and other transactional fees. Although your
actual costs may be higher or lower, based on these assumptions your costs
would be:

<TABLE>
<CAPTION>
                                                                                             Life of
      1 Year                          3 Years                                               Portfolio
      -------                         -------                                               ---------
      <S>                             <C>                                                   <C>
      $506.80                         $697.01                                                $862.31
</TABLE>

See "Trust Operating Expenses" in Part B of the Prospectus for additional in-
formation regarding expenses.

                                      ---
                                       5
<PAGE>

- --------------------------------------------------------------------------------
Schedule of Investments

(at the Initial Date of Deposit, February 17, 2000)

     Nuveen--Dow Jones Global Titans IndexSM Portfolio, February 2000

<TABLE>
<CAPTION>
                                                                                 Market       Cost of
Number of                                               Ticker   Percentage of  Value per  Securities to
 Shares          Name of Issuer of Securities(1)        Symbol     Index(3)       Share      Trust(2)
- --------------------------------------------------------------------------------------------------------
<S>        <C>                                         <C>       <C>           <C>         <C>
           Aerospace/Defense                                         0.57%
      5    The Boeing Company                          BA            0.57      $    37.313    $   187
           Auto--Cars/Light Trucks                                   5.30
      5    DaimlerChrysler AG                          DCXGn.F       1.03          64.7933        324
      5    Ford Motor Company                          F             0.84          46.1250        231
      5    General Motors Corporation                  GM            0.79          74.7500        374
  1,000    Toyota Motor                                7203.T        2.64          41.1485     41,149
           Beverages--Non-Alcoholic                                  2.20
      5    The Coca-Cola Company                       KO            2.20          53.7500        269
           Chemicals--Diversified                                    1.14
      5    E.I. du Pont de Nemours and Company         DD            1.14          53.3750        267
           Computers--Software                                       8.37
      5    Microsoft Corporation                       MSFT          8.37          97.6250        488
           Computers--Micro                                          5.28
      5    Hewlett-Packard Company                     HWP           1.99         129.0625        645
      5    International Business Machines Corporation IBM           3.29         115.6250        578
           Cosmetics & Toiletries                                    1.92
      5    The Procter & Gamble Company                PG            1.92          93.3750        467
           Diversified Financial Services                            4.89
      5    Citigroup Inc.                              C             2.85          53.5000        268
      5    Lloyds TSB Group Plc                        LLOY.L        0.87           9.4684         47
      5    Morgan Stanley Dean Witter & Co.            MWD           1.17          64.8750        324
           Diversified Manufacturing                                 8.52
      5    General Electric Company                    GE            6.86         134.5625        673
      5    Siemens AG                                  SIEG.F        1.66         160.7506        804
           Food--Misc/Diversified                                    1.39
      5    Nestle SA                                   NSRGY         1.02       1,630.4682      8,152
      5    Unilever NV                                 cva Ntfl4     0.37          46.6437        233
           Medical Products                                          1.73
      5    Johnson & Johnson                           JNJ           1.73          79.8125        399
           Medical--Drugs                                            5.30
      5    Merck & Co., Inc.                           MRK           2.59          65.6250        328
     10    Novartis AG                                 NOVZn.S       1.43       1,267.4583     12,675
      5    Roche Holding Ltd.                          ROCZg.S       1.28      11,197.9327     55,990
           Money Center Banks                                        7.20
      5    Bank of America Corporation                 BAC           1.23          45.1875        226
  1,000    Bank of Tokyo-Mitsubishi, Ltd.              8315.T        0.92          11.7228     11,723
      5    The Chase Manhattan Corporation             CMB           1.06          79.5000        398
     10    Credit Suisse Group                         CSGZn.S       0.78         176.8904      1,769
      5    HSBC Holdings, Plc                          HSBA.L        1.52          12.0610         60
      5    ING Groep N.V.                              ING.AS        0.85          54.5021        273
     10    UBS AG                                      UBSZn.S       0.84         250.4153      2,504
           Multi-Line Insurance                                      4.40
      5    Allianz AG                                  ALVG.DE       1.34         363.9078      1,820
      5    American International Group, Inc.          AIG           2.35          94.3125        472
      5    AXA                                         AXA           0.71         129.6853        648
           Multimedia                                                1.21
      5    The Walt Disney Company                     DIS           1.21          36.9375        185
           Oil Companies--Integrated                                 9.61
      5    BP Amoco Plc                                BPA.L         2.29           8.0682         40
      5    Chevron Corporation                         CHV           0.77          77.9375        390
    500    ENI SpA                                     ENI.IM        0.67           5.3048      2,652
      5    Exxon Mobil Corporation                     XOM           4.11          79.1875        396
      5    Royal Dutch Petroleum Company               RD.AS         1.77          58.6291        293
           Retail--Discount                                          3.98
      5    Wal-Mart Stores, Inc.                       WMT           3.98          52.8750        264
           Semiconductors                                            5.45
      5    Intel Corporation                           INTC          5.45         107.1875        536
</TABLE>

                                      ---
                                       6
<PAGE>

- --------------------------------------------------------------------------------
Schedule of Investments--(continued)

(at the Initial Date of Deposit, February 17, 2000)

     Nuveen--Dow Jones Global Titans IndexSM Portfolio, February 2000

<TABLE>
<CAPTION>
                                                                              Market      Cost of
Number of                                              Ticker  Percentage of Value per Securities to
 Shares          Name of Issuer of Securities(1)       Symbol    Index(3)      Share     Trust(2)
- ----------------------------------------------------------------------------------------------------
<S>        <C>                                         <C>     <C>           <C>       <C>
           Telecommunications Equipment                             2.58
      5    Lucent Technologies Inc.                    LU           2.58     $ 52.3750   $    262
           Telephone Integrated                                    13.41%
      5    AT&T Corp.                                  T            2.43       49.6875        248
      5    British Telecommunications Plc              BTY          1.76       15.6478         78
      5    Deutsche Telekom AG                         DTEG.DE      4.34       83.8270        419
      5    France Telecom SA                           FTE.PA       2.61      152.8610        764
      5    SBC Communications Inc.                     SBC          2.27       38.8125        194
           Telephone--Local                                         2.69
      5    Bell Atlantic Corporation                   BEL          1.40       55.0625        275
      5    Bellsouth Corporation                       BLS          1.29       42.4375        212
           Telephone--Long Distance                                 2.13
      5    MCI WorldCom, Inc.                          WCOM         2.13       47.9375        240
           Tobacco                                                  0.73
      5    Philip Morris Companies Inc.                MO           0.73       18.8750         94
  -----                                                           ------                 --------
  2,750                                                           100.00%                $152,307
  =====                                                           ======                 ========
</TABLE>
- ---------
See "Notes to Portfolios."

Advertising and sales literature may include brief descriptions of the
principal businesses of the companies represented in the Portfolio.

Please note that if this prospectus is used as a preliminary prospectus for fu-
ture Nuveen Defined Portfolios, the portfolio will contain different stocks
from those described above.

                                      ---
                                       7
<PAGE>


Nuveen Nasdaq 100 Index Portfolio, February 2000

Risk/Return Summary

Investment Objective

The Portfolio seeks to provide capital appreciation.

Investment Strategy

The Portfolio consists of the securities included in the Nasdaq 100 Index. The
securities held by the Portfolio will be periodically adjusted to generally
replicate the current selections and weightings of the Nasdaq 100 Index.

Security Selection

We select the securities for the Portfolio in the following manner:

 . On the Initial Date of Deposit, the Portfolio consists of each of the stocks
  included in the Nasdaq 100 Index.

 . During an initial adjustment period that will not exceed 30 days, the Port-
  folio will be modified to duplicate, to the extent practicable, the stocks
  contained in the index and their weightings.

 . Following the initial adjustment period, it is expected that:

 --The Portfolio will continue to be invested in substantially all (at least
  95%) of the stocks in the index; and

 --The Sponsor will attempt to maintain a correlation between the Portfolio's
  holdings and the index of .97 to .99 over the term of the Portfolio. Howev-
  er, the performance of the Portfolio may not mirror the performance of the
  index.

 . Adjustments to the Portfolio's holdings will be made on an ongoing basis
  when:

 --The Portfolio invests in new securities to create new Units;

 --Issues are removed from or added to the index;

 --Securities are sold to meet redemptions, to pay sales charges and ex-
  penses, or for tax reasons; or

 --It is necessary to maintain the correlation between the Portfolio and the
  index.

See "Composition of Trusts," "The Portfolios," and "Investment Supervision" in
Part B of the Prospectus for details.

The Nasdaq 100 Index

The Nasdaq 100 Index is composed of 100 of the largest non-financial domestic
and international issues listed on the Nasdaq Stock Market, Inc. ("Nasdaq").
The Nasdaq lists nearly 5,000 companies and trades more shares per day than
any other major U.S. market. See "The Nasdaq 100 Index" in Part B of the Pro-
spectus for additional information regarding the Index.

Industry Diversification

Based upon the principal business of each issuer and current market values,
the index as of February 9, 2000, represented the following industries:

<TABLE>
<CAPTION>
                                Approximate
Industry                      Index Percentage
- --------                      ----------------
<S>                           <C>
Biotechnology                       5.00%
Commercial Services                 1.00%
Computers                          16.92%
Electronics                         3.11%
Health Care                         0.45%
Media                               1.59%
Retail                              2.82%
Semiconductors                     14.41%
Software                           26.38%
Telecommunications Equipment       13.42%
Telecommunications                  8.93%
Telephone                           2.74%
Other                               3.23%
                                   ------
    Total                            100%
</TABLE>

Primary Risks

You can lose money by investing in the Portfolio. In addition, the Portfolio
may not perform as well as you hope. These things can happen for various rea-
sons, including:

 . Stock prices can be volatile.

 . Share prices or dividend rates on the stocks may decline during the life of
  the Portfolio.

 . The Portfolio is not actively managed and may continue to purchase or hold a
  stock included in the index even though the stock's outlook or its market
  value or yield may have changed.

 . The Portfolio is concentrated in the software and technology industries. Ad-
  verse developments in these industries may affect the value

                                      ---
                                       8
<PAGE>


  of your Units. Companies involved in the software and technology industries
  must contend with rapid changes in technology, intense competition, govern-
  ment regulation, and the rapid obsolescence of products and services.

 . The Portfolio may contain stocks of foreign companies. The Portfolio's in-
  vestment in foreign stock presents additional risk. Foreign companies may be
  affected by adverse political, diplomatic and economic developments; changes
  in foreign currency exchange rates; taxes; less publicly available informa-
  tion; greater price volatility; less liquidity and other factors.

 . The performance of the Portfolio may not sufficiently correspond with the
  performance of the index. This is due to a variety of factors that include:

 --the impracticability of owning each of the securities in the index with
  the exact weightings at any given time;

 --the possibility of tracking errors;

 --the time that elapses between a change in the index and a change in the
  Portfolio; and

 --sales charges and expenses.

Investor Suitability

The Portfolio may be suitable for you if:

 . You are seeking to own the components of the Nasdaq 100 Index in one conve-
  nient package;

 . You want capital appreciation potential; and

 . The Portfolio represents only a portion of your overall investment portfolio.

The Portfolio is not appropriate for you if:

 . You are unwilling to take the risks involved with owning an unmanaged index-
  based equity investment;

 . You are seeking preservation of capital or high current income; or

 . You do not have a long-term investment horizon.

Fees and Expenses

This table shows the fees and expenses you may pay, directly or indirectly,
when you invest in the Portfolio.
<TABLE>
<CAPTION>
                                                                    Approximate
                                                                    % of Public
                                                                     Offering
                                                    Amount per Unit  Price (1)
                                                    --------------- -----------
<S>                                                 <C>             <C>
Sales Charge
Maximum Sales Charge (Deferred)(2) ................     $ 0.450        4.50%(2)

Estimated Annual Operating Expenses

Trustee's Fee......................................     $0.0095       0.095%
Sponsor's Supervisory Fee..........................     $0.0035       0.035%
Bookkeeping and Administrative Fees................     $0.0025       0.025%
Evaluator's Fees...................................     $0.0030       0.030%
Other Operating Expenses(3)........................     $0.0055       0.055%
                                                        -------       ------
Total..............................................     $0.0240       0.240%
Maximum Organization Costs(4)......................     $0.0225       0.225%
</TABLE>
- ---------

(1) Based on 100 Units with a $10 per Unit Public Offering Price as of the
    Initial Date of Deposit.

(2) The maximum sales charge is a fixed dollar amount of $0.45 per Unit, how-
    ever, the maximum sales charge may not exceed 5.5% of the Public Offering
    Price. The entire sales charge is deferred for investors who purchase
    Units prior to the first deferred sales charge deduction (see below).

(3) Other Operating Expenses include annual licensing fees paid to cover a li-
    cense to use service marks, trademarks and trade names of Nasdaq but do
    not include brokerage costs and other transactional fees.

(4) Organization costs are deducted from Portfolio assets at the earlier of
    the close of the initial offering period or 6 months after Initial Date of
    Deposit.

The entire sales charge is deferred and deducted monthly in installments of
$0.09 per Unit from September 29, 2000 through January 31, 2001. However, for
Units purchased after the beginning of the deferred sales charge period you
will pay an up-front sales charge equal to the deferred sales charges already
collected. The maximum sales charge will not exceed 5.5% of the Public Offer-
ing Price of the Units.

                                      ---
                                       9
<PAGE>

The maximum per Unit sales charges are reduced as follows:

<TABLE>
<CAPTION>
                                                               Your maximum
If you buy the following number of Units:*                 sales charge will be:
- ---------------------------------------------------------- ---------------------
<S>                                                        <C>
Less than 5,000...........................................        $0.450
5,000 to 9,999............................................        $0.425
10,000 to 24,999..........................................        $0.400
25,000 to 49,999..........................................        $0.350
50,000 to 99,999..........................................        $0.250
100,000 or more...........................................        $0.150
</TABLE>

 * Sales charge reductions are computed both on a dollar basis and on the ba-
   sis of the number of Units purchased, using the equivalent of 5,000 Units
   to $50,000, 10,000 Units to $100,000 etc., and will be applied on that ba-
   sis which is more favorable to you.

As described in "Public Offering Price" in Part B of the Prospectus, certain
classes of investors are also entitled to reduced sales charges.

Example

This example may help you compare the cost of investing in the Portfolio to
the cost of investing in other funds.

The example assumes that you invest $10,000 in the Portfolio for the periods
indicated and then either redeem or do not redeem your Units at the end of
those periods. The example also assumes a 5% return on your investment each
year and that the Portfolio's operating expenses stay the same. The example
does not include brokerage costs and other transactional fees. Although your
actual costs may be higher or lower, based on these assumptions your costs
would be:

<TABLE>
<CAPTION>
                                                                                             Life of
      1 Year                          3 Years                                               Portfolio
      -------                         -------                                               ---------
      <S>                             <C>                                                   <C>
      $496.50                         $545.66                                                $599.61
</TABLE>

See "Trust Operating Expenses" in Part B of the Prospectus for additional in-
formation regarding expenses.

                                      ---
                                      10
<PAGE>

- --------------------------------------------------------------------------------
Schedule of Investments

(at the Initial Date of Deposit, February 17, 2000)

             Nuveen Nasdaq 100 Index Portfolio, February 2000

<TABLE>
<CAPTION>
                                                                             Market      Cost of
Number of                                              Ticker Percentage of Value per Securities to
 Shares          Name of Issuer of Securities(1)       Symbol   Index(3)      Share   Portfolio(2)
- ---------------------------------------------------------------------------------------------------
<S>        <C>                                         <C>    <C>           <C>       <C>
   125     Microsoft Corporation                       MSFT       9.02%     $97.6250     $12,203
    83     Cisco Systems, Inc.                         CSCO       7.43      127.1719      10,555
    82     Intel Corporation                           INTC       6.01      107.1875       8,789
    59     QUALCOMM Incorporated                       QCOM       5.51      121.0000       7,139
    83     Oracle Corporation                          ORCL       3.53       61.2500       5,084
    23     JDS Uniphase Corporation                    JDSU       2.90      212.9375       4,898
    53     Sun Microsystems, Inc.                      SUNW       2.71       92.0000       4,876
    32     Nextel Communications, Inc.                 NXTL       2.70      120.4844       3,856
    72     MCI WORLDCOM, Inc.                          WCOM       2.37       47.9375       3,452
    18     Yahoo! Inc.                                 YHOO       2.21      161.5625       2,908
    59     Global Crossing Ltd.                        GBLX       2.16       58.0000       3,422
    18     VERITAS Software Corporation                VRTS       2.09      166.1875       2,991
    16     Immunex Corporation                         IMNX       1.78      170.9375       2,735
    21     CMGI, Inc.                                  CMGI       1.72      110.6250       2,323
    66     Dell Computer Corporation                   DELL       1.61       38.0000       2,508
    14     Applied Materials, Inc.                     AMAT       1.54      173.3750       2,427
    33     Amgen Inc.                                  AMGN       1.53       69.8750       2,306
    17     Level 3 Communications, Inc.                LVLT       1.36      111.1250       1,889
    16     Apple Computer, Inc.                        AAPL       1.22      113.9375       1,823
    30     Xilinx, Inc.                                XLNX       1.18       65.2500       1,958
    29     Maxim Integrated Products, Inc.             MXIM       1.13       54.3750       1,577
    15     Conexant Systems, Inc.                      CNXT       1.09      122.4375       1,837
    17     LM Ericsson Telephone Company               ERICY      1.06       87.0000       1,479
    16     Siebel Systems, Inc.                        SEBL       1.06      107.9375       1,727
    14     Linear Technology Corporation               LLTC       1.05      101.7500       1,425
    11     PMC-Sierra, Inc.                            PMCS       1.04      160.8125       1,769
    20     Altera Corporation                          ALTR       1.00       76.5625       1,531
    11     Network Appliance, Inc.                     NTAP       0.97      164.2500       1,807
     6     i2 Technologies, Inc.                       ITWO       0.92      272.1875       1,633
     7     Citrix Systems, Inc.                        CTXS       0.90      168.1250       1,177
    16     Amazon.com, Inc.                            AMZN       0.87       70.6875       1,131
    13     Biogen, Inc.                                BGEN       0.85      107.5625       1,398
    15     Metromedia Fiber Network, Inc.              MFNX       0.84       75.3750       1,131
    25     Comcast Corporation                         CMCSK      0.82       46.1250       1,153
    18     Intuit Inc.                                 INTU       0.78       61.0625       1,099
     7     eBay Inc.                                   EBAY       0.76      140.6875         985
     7     VoiceStream Wireless Corporation            VSTR       0.72      149.9375       1,050
     6     Comverse Technology, Inc.                   CMVT       0.71      194.5625       1,167
    15     KLA-Tencor Corporation                      KLAC       0.71       71.7500       1,076
    28     Novell, Inc.                                NOVL       0.71       40.7500       1,141
    16     Tellabs, Inc.                               TLAB       0.70       58.0000         928
     6     BroadVision, Inc.                           BVSN       0.69      182.5000       1,095
    15     Gemstar International Group, Limited        GMST       0.68       76.0000       1,140
     5     Applied Micro Circuits Corporation          AMCC       0.67      225.3750       1,127
    11     CIENA Corporation                           CIEN       0.65      117.6875       1,295
    10     NTL Incorporated                            NTLI       0.64       84.3125         843
    26     ADC Telecommunications, Inc.                ADCT       0.63       41.6250       1,082
    16     Costco Wholesale Corporation                COST       0.59       47.7500         764
    10     RealNetworks, Inc.                          RNWK       0.58       86.4375         864
    18     Chiron Corporation                          CHIR       0.56       45.0625         811
     3     SDL, Inc.                                   SDLI       0.55      319.6875         959
    12     3Com Corporation                            COMS       0.50       74.8125         898
     8     Adobe Systems Incorporated                  ADBE       0.49       98.1875         786
     5     MedImmune, Inc.                             MEDI       0.49      181.2500         906
     8     EchoStar Communications Corporation         DISH       0.48       91.4375         732
</TABLE>

                                      ---
                                       11
<PAGE>

<TABLE>
<CAPTION>
                                                                             Market      Cost of
Number of                                              Ticker Percentage of Value per Securities to
 Shares          Name of Issuer of Securities(1)       Symbol   Index(3)      Share   Portfolio(2)
- ---------------------------------------------------------------------------------------------------
<S>        <C>                                         <C>    <C>           <C>       <C>
     14    PanAmSat Corporation                        SPOT        0.47%    $ 46.3750   $    649
     19    At Home Corporation                         ATHM        0.46       34.1875        650
     16    Paychex, Inc.                               PAYX        0.46       45.7500        732
     27    PeopleSoft, Inc.                            PSFT        0.46       23.8750        645
      3    Network Solutions, Inc.                     NSOL        0.45      303.0000        909
     12    Vitesse Semiconductor Corporation           VTSS        0.44       66.4375        797
      9    Lycos, Inc.                                 LCOS        0.43       72.6250        654
      6    RF Micro Devices, Inc.                      RFMD        0.42       97.3125        584
     18    Starbucks Corporation                       SBUX        0.42       34.1875        615
      9    McLeodUSA Incorporated                      MCLD        0.40       77.8750        701
     11    USA Networks, Inc.                          USAI        0.40       48.5625        534
     26    Parametric Technology Corporation           PMTC        0.38       22.2500        579
     22    Staples, Inc.                               SPLS        0.38       24.3750        536
      9    Adelphia Communications Corporation         ADLAC       0.37       56.4375        508
     13    BMC Software, Inc.                          BMCS        0.37       41.7500        543
      6    NEXTLINK Communications, Inc.               NXLK        0.37      104.6875        628
     18    American Power Conversion Corporation       APCC        0.36       31.4375        566
      5    QLogic Corporation                          QLGC        0.35      101.4375        507
      5    Sanmina Corporation                         SANM        0.35      112.8750        564
      7    Genzyme Corporation                         GENZ        0.28       52.9375        371
     12    Atmel Corporation                           ATML        0.27       39.3125        472
     13    Bed Bath & Beyond Inc.                      BBBY        0.27       27.9375        363
     11    Biomet, Inc.                                BMET        0.27       34.5000        380
      9    Cintas Corporation                          CTAS        0.27       39.4375        355
     11    Fiserv, Inc.                                FISV        0.25       32.0000        352
     16    Concord EFS, Inc.                           CEFT        0.24       18.4375        295
      4    Electronic Arts Inc.                        ERTS        0.24       85.0000        340
     11    Quintiles Transnational Corp.               QTRN        0.23       30.1250        331
     15    Compuware Corporation                       CPWR        0.22       24.0625        361
      6    Adaptec, Inc.                               ADPT        0.20       44.1875        265
      5    Molex Incorporated                          MOLX        0.20       52.1250        261
      6    CNET, Inc.                                  CNET        0.19       61.0000        366
      6    Synopsys, Inc.                              SNPS        0.19       44.5625        267
      6    PACCAR Inc.                                 PCAR        0.18       44.8125        269
     15    Smurfit-Stone Container Corporation         SSCC        0.18       18.0000        270
      7    Legato Systems, Inc.                        LGTO        0.16       33.2500        233
     10    Network Associates, Inc.                    NETA        0.16       30.1250        301
      7    Sigma-Aldrich Corporation                   SIAL        0.16       27.0000        189
      4    Microchip Technology Incorporated           MCHP        0.14       48.1250        193
      4    Dollar Tree Stores, Inc.                    DLTR        0.12       36.7500        147
      3    PacifiCare Health Systems, Inc.             PHSY        0.09       42.8750        129
      5    VISX, Incorporated                          VISX        0.09       26.0000        130
      5    Apollo Group, Inc.                          APOL        0.07       23.3125        117
      4    Herman Miller, Inc.                         MLHR        0.06       21.3750         86
      5    Northwest Airlines Corporation              NWAC        0.06       17.1875         86
  -----                                                          ------                 --------
  1,840                                                          100.00%                $148,495
  =====                                                          ======                 ========
</TABLE>
- ---------
See "Notes to Portfolios."

Advertising and sales literature may include brief descriptions of the
principal businesses of the companies represented in the Portfolio.

Please note that if this prospectus is used as a preliminary prospectus for
future Nuveen Defined Portfolios, the portfolio will contain different stocks
from those described above.


                                      ---
                                       12
<PAGE>

How to Buy and Sell Units

Investing in a Portfolio

The minimum investment is normally $1,000 or 100 Units, whichever is less.
However, for IRA purchases the minimum investment is $500 or the nearest whole
number of Units whose value is less than $500.

You can buy Units from any participating dealer.

As of February 17, 2000, the Initial Date of Deposit, the per Unit Public Of-
fering Price for each Portfolio is $10.00. As described above, Units are sub-
ject to deferred sales charges and in some cases, an up-front sales charge.
The Public Offering Price includes the up-front sales charge, if applicable,
and estimated organization costs of $0.0225 per Unit. The Public Offering
Price changes every day with changes in the price of the securities. As of the
close of business on February 17, 2000, the number of Units of each Portfolio
may be adjusted so that the per Unit Public Offering Price will equal $10.00.

Wrap Account Purchases and certain other investors descsribed in Part B of the
Prospectus, may buy Units with a reduced sales charge of $0.100 per Unit. All
distributions (other than the liquidation distribution) from Units that re-
ceive the reduced sales charges for Wrap Account Purchases will be invested in
additional Units of the Portfolio and will be subject to any remaining de-
ferred sales charges.

Each Portfolio's securities are valued by the Evaluator, The Chase Manhattan
Bank, generally on the basis of their closing sales prices on the applicable
national or foreign securities exchange or The Nasdaq Stock Market, Inc. every
business day.

The Sponsor intends to periodically create additional Units of the Portfolios.
See "Nuveen Defined Portfolios" and "Composition of Trusts" in Part B of the
Prospectus for more details.

See "Public Offering Price" and "Market for Units" in Part B of the Prospectus
for additional information.

Sales or Redemptions

Units may be redeemed by the Trustee, The Chase Manhattan Bank, on any busi-
ness day at their current market value.

Although not obligated to do so, the Sponsor, may maintain a market for Units
and offer to repurchase the Units at prices based on their current market val-
ue. If a secondary market is not maintained, a Unitholder may still redeem
Units through the Trustee.

During the period ending with the earlier of six months after the Initial Date
of Deposit or the end of the initial offering period, the price at which the
Trustee will redeem Units and the price at which the Sponsor may repurchase
Units include estimated organization costs. After such period, the amount paid
will not include such estimated organization costs.

Any applicable deferred sales charges remaining on Units at the time of their
sale or redemption will be collected at that time.

See "Redemption" and "Market for Units" in Part B of the Prospectus for de-
tails.

Risk Factors

You can lose money by investing in a Portfolio. Recently, equity markets have
experienced significant volatility. Your investment is at risk primarily be-
cause of:

 . Market risk

  Market risk is the risk that a particular stock in a Portfolio, the Portfo-
  lio itself or stocks in general may fall in value. Market value may be af-
  fected by a variety of factors including:

  --General stock market movements;

  --Changes in the financial condition of an issuer or an industry;

  --Changes in perceptions about an issuer or an industry;

  --Interest rates and inflation;

  --Governmental policies and litigation; and

  --Purchases and sales of securities by a Portfolio.

 . Inflation risk

  Inflation risk is the risk that the value of assets or income from invest-
  ments will be less in the future as inflation decreases the value of money.

 . Correlation risk

  The performance of a Portfolio may not sufficiently correspond to the per-
  formance of the

                                      ---
                                      13
<PAGE>

  index due to a variety of factors that include:

  --The impracticability of owning each of the securities in the index with
   the exact weighting at a given time;

  --The possibility of tracking errors;

  --The time that elapses between a change in the index and a change in a
   Portfolio; and

  --Sales charges and expenses.

 . Concentration risk

  When stocks in a particular industry make up 25% or more of a Portfolio, it
  is said to be "concentrated" in that industry, which makes the Portfolio
  less diversified and subject to more market risk. The Nasdaq 100 Portfolio
  is concentrated in the securities of software and technology companies.

  Here is what you should know about the Nasdaq 100 Portfolio's concentration
  in stocks of the software and technology industries:

  --Companies involved in these industries must contend with:

   rapid changes in technology;

   worldwide competition;

   rapid obsolescence of products and services;

   cyclical market patterns;

   government regulation;

   evolving industry standards; and

   frequent new product introductions.

  --The stocks of many software and technology companies have exceptionally
   high price-to-earnings ratios with little or no earnings histories.

  --Many software and technology companies have experienced extreme price and
   volume fluctuations that often have been unrelated to their operating per-
   formance.

  --An unexpected change in one or more of the technologies affecting an is-
   suer's products or in the market for products based on a particular tech-
   nology could have an adverse effect on an issuer's operating results.

  --Operating results and customer relationships could be adversely affected
   by:

   an increase in price for, or an interruption or reduction in supply of,
   any key components; and

   the failure of the issuer to comply with rigorous industry standards.

 .Foreign risks

  Certain of the securities included in the Portfolios may be stocks and/or
  American Depositary Receipts ("ADRs") of foreign companies. ADRs are denomi-
  nated in U.S. dollars and are typically issued by a U.S. bank or trust com-
  pany. An ADR evidences ownership of an underlying foreign security. Foreign
  securities present risks beyond securities of U.S. issuers. Such risks in-
  clude:

  --adverse political, diplomatic and economic developments;

  --Political or economic instability;

  --higher brokerage costs;

  --currency risk;

  --less liquidity;

  --more volatile prices;

  --reduced government regulation;

  --different accounting standards;

  --foreign taxation; and

  --less publicly available information.

  The purchase and sale of foreign securities not listed on a U.S. securities
  exchange will occur only in foreign securities markets. Some of the factors
  described above may make it impossible to buy or sell such securities in a
  timely manner. Custody of certain of the securities held in a Portfolio is
  maintained by Cedel Bank S.A., a global custody and clearing institution
  which has entered into a sub-custodian relationship with the Trustee.

  The U.S. and foreign equity markets often rise and fall at different times
  or by different amounts due to economic or other developments particular to
  a given country. This phenomenon would tend to lower the overall price vola-
  tility of a portfolio that included both U.S. and foreign stocks. Sometimes,
  however, global trends will cause the U.S. and foreign markets to move in
  the same direction, reducing or eliminating the risk reduction benefit of
  international investing.

 .Currency risks

  Because securities of foreign issuers generally pay dividends and trade in
  foreign currencies,

                                      ---
                                      14
<PAGE>

  the U.S. dollar value of these securities (and therefore your Units) will
  vary with fluctuations in foreign exchange rates. Most foreign currencies
  have fluctuated widely in value against the U.S. dollar for various economic
  and political reasons.

  To determine the value of foreign securities, or their dividends, the
  Trustee will estimate current exchange rates for the relevant currencies
  based on activity in the various currency exchange markets. However, these
  markets can be quite volatile, depending on the activity of the large inter-
  national commercial banks, various central banks, large multi-national cor-
  porations, speculators and other buyers and sellers of foreign currencies.
  Since actual foreign currency transactions may not be instantly reported,
  the exchange rates estimated by the Trustee may not reflect the amount a
  Portfolio would receive, in U.S. dollars, had the Trustee sold any particu-
  lar currency in the market. When instructed by the Sponsor, the Evaluator,
  The Chase Manhattan Bank, may utilize its own, or an affiliates, exchange
  rate quotations.

 . Litigation

  Microsoft Corporation is currently engaged in litigation with Sun
  Microsystems, Inc., the U.S. Department of Justice, several state Attorneys
  General and Caldera, Inc. The complaints against Microsoft include, copy-
  right infringement, unfair competition, and antitrust violations. The claims
  seek injunctive relief and monetary damages. As of February 11, 2000,
  Microsoft's management asserted that resolving these matters will not have a
  material adverse impact on its financial position or its results of opera-
  tion.

Distributions

Income Distributions

Cash dividends received by a Portfolio, net of expenses, will be paid each
June 30 and December 31 ("Income Distribution Dates"), beginning June 30,
2000, to Unitholders of record each June 15 and December 15 ("Income Record
Dates"), respectively.

Capital Distributions

Distributions of funds in the Capital Account, net of expenses, will be made
annually each December 31 ("Capital Distribution Date") to Unitholders of rec-
ord each December 15 ("Capital Record Date"). In certain circumstances, addi-
tional distributions may be made.

See "Distributions To Unitholders" in Part B of the Prospectus for more de-
tails.

General Information

Termination

Commencing on February 16, 2005, the Mandatory Termination Date, the securi-
ties in each Portfolio will begin to be sold as prescribed by the Sponsor. The
Trustee will provide written notice of the termination to Unitholders which
will specify when certificates may be surrendered.

Unitholders will receive a cash distribution within a reasonable time after
each Portfolio's termination. See "Distributions to Unitholders" and "Other
Information--Termination of Indenture" in Part B of the Prospectus for more
details.

The Sponsor

Since our founding in 1898, John Nuveen & Co. Incorporated has been synonymous
with investments that withstand the test of time. Today, we offer a range of
equity and fixed-income unit trusts designed to suit the unique circumstances
and financial planning needs of mature investors. Nuveen, a leader in tax-ef-
ficient investing, believes that a carefully selected portfolio can play an
important role in building and sustaining the wealth of a lifetime. More than
1.5 million investors have trusted Nuveen to help them maintain the lifestyle
they currently enjoy.

The Prospectus describes in detail the investment objectives, policies and
risks of the Portfolios. We invite you to discuss the contents with your fi-
nancial adviser, or you may call us at 800-257-8787 for additional informa-
tion.

Dealer Concessions

The Sponsor plans to allow a concession of $0.35 per Unit for non-breakpoint
purchases of Units to dealer firms in connection with the sale of Units in a
given transaction. But, in no event will the concession exceed 4.279% of the
Public Offering Price.

The concession paid to dealers is reduced or eliminated in connection with
Units sold in

                                      ---
                                      15
<PAGE>


transactions to investors that receive reduced sales charges based on the num-
ber of Units sold or in connection with Units sold in Wrap Account Purchases
and other investors entitled to the sales charge reduction applicable for Wrap
Account Purchases, as follows:

- -------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                    $ Concession
Number of Units*                                                      per Unit
- ----------------                                                    ------------
<S>                                                                 <C>
Less than 5,000....................................................    $0.350
5,000 to 9,999.....................................................    $0.325
10,000 to 24,999...................................................    $0.300
25,000 to 49,999...................................................    $0.250
50,000 to 99,999...................................................    $0.150
100,000 or more....................................................    $0.075
Wrap Accounts......................................................     0.000
</TABLE>
*Sales charge reductions are computed both on a dollar basis and on the basis
of the number of Units purchased, using the equivalent of 5,000 Units to
$50,000, 10,000 Units to $100,000 etc., and will be applied on that basis
which is more favorable to the purchaser and may result in a reduction in the
discount per Unit.

See "Distributions of Units to the Public" in Part B of the Prospectus for ad-
ditional information on dealer concessions and volume incentives.

Optional Features

Letter of Intent (LOI)

Investors may use a Letter of Intent to get reduced sales charges on purchases
made over a 13-month period (and to take advantage of dollar cost averaging).
The minimum LOI investment is $50,000. See "Public Offering Price" in Part B
of the Prospectus for details.

Reinvestment

Distributions from a Portfolio can be invested with no sales charge into
Nuveen mutual or money market funds. Also, income and certain capital distri-
butions from a Portfolio can be reinvested at a reduced sales charge into ad-
ditional Units of the Portfolio. Distributions reinvested into a Portfolio are
subject to any remaining deferred sales charges. See "Distributions to
Unitholders" and "Accumulation Plan" in Part B of the Prospectus for details.

Nuveen Mutual Funds

Unit purchases may be applied toward breakpoint pricing discounts for Nuveen
Mutual Funds. For more information about Nuveen investment products, obtain a
prospectus from your financial adviser.


                                      ---
                                      16
<PAGE>

- -------------------------------------------------------------------------------
Notes to Portfolios

(1) All securities are represented by regular way contracts to purchase such
    securities for the performance of which an irrevocable letter of credit
    has been deposited with the Trustee. The contracts to purchase the securi-
    ties were entered into by the Sponsor on February 16, 2000.

(2) The cost of the securities to the Portfolio represents the aggregate un-
    derlying value with respect to the securities acquired (generally deter-
    mined by the closing sale prices of the listed securities on the business
    day preceding the Initial Date of Deposit). The valuation of the securi-
    ties has been determined by the Trustee. As of the Initial Date of Depos-
    it, other information regarding the securities is as follows:

<TABLE>
<CAPTION>
                          Value of  Cost to   Gain
                         Securities Sponsor  (loss)
                         ---------- -------- ------
<S>                      <C>        <C>      <C>
Global Titans Portfolio   $152,307  $152,845 $(538)
NASDAQ 100 Portfolio       148,495   148,759  (264)
</TABLE>

(3) The percentages listed represent each security's proportionate relation-
    ship of all index stocks based on market value as of February 9, 2000. Be-
    cause the stocks included in the index and the value of such stocks may
    change from time to time, and because the Portfolio may not be able to du-
    plicate the index exactly, the percentages set forth do not represent the
    actual weighting of each security listed in the Schedule of Investments on
    the Initial Date of Deposit or on any subsequent date.


Please note that if this prospectus is used as a preliminary prospectus for
future Nuveen Defined Portfolios, the portfolio will contain different stocks
from those described above.

- -------------------------------------------------------------------------------

                                      ---
                                      17
<PAGE>


Statements of Condition

(at the Initial Date of Deposit, February 17, 2000)

<TABLE>
<CAPTION>
                                                             Global    Nasdaq
                                                             Titans      100
                                                            Portfolio Portfolio
                                                            --------- ---------
<S>                                                         <C>       <C>
Trust Property
Investment in securities represented by purchase con-
 tracts(1)(2).............................................  $152,307  $148,495
                                                            ========  ========
Liabilities and Interest of Unitholders
Liabilities:
  Deferred sales charge(3)................................  $  6,854  $  6,682
  Reimbursement of Sponsor for organization costs(4)......  $    343  $    334
                                                            --------  --------
     Total................................................  $  7,197  $  7,016
                                                            ========  ========
Interest of Unitholders:
  Units of fractional undivided interest outstanding......    15,230    14,849
  Cost to investors(5)....................................  $152,307  $148,495
   Less: Gross underwriting commission(6).................  $  6,854  $  6,682
   Less: Organization costs(4)............................  $    343  $    334
                                                            --------  --------
  Net amount applicable to investors......................  $145,110  $141,479
                                                            --------  --------
     Total................................................  $152,307  $148,495
                                                            ========  ========
</TABLE>
- ---------

(1) Aggregate cost of securities listed under "Schedule of Investments" is
    based on their aggregate underlying value.

(2) An irrevocable letter of credit has been deposited with the Trustee as
    collateral, which is sufficient to cover the monies necessary for the pur-
    chase of the securities pursuant to contracts for the purchase of such se-
    curities.

(3) Represents the amount of mandatory distributions from a Portfolio ($0.45
    per Unit), payable to the Sponsor in five equal monthly installments of
    $0.09 per Unit beginning on September 29, 2000, and on the last business
    day of each month thereafter through January 31, 2001.

(4) A portion of the Public Offering Price consists of an amount sufficient to
    reimburse the Sponsor for all or a portion of the costs of establishing a
    Portfolio. These costs have been estimated at $0.0225 per Unit for each
    Portfolio. A payment will be made as of the earlier of six months after
    the Initial Date of Deposit or the end of the initial offering period to
    an account maintained by the Trustee from which the obligations of the in-
    vestors to the Sponsor will be satisfied. To the extent that actual organ-
    ization costs are greater than the estimated amount, only the estimated
    organization costs added to the Public Offering Price will be reimbursed
    to the Sponsor and deducted from the assets of each Portfolio.

(5) Aggregate Public Offering Price computed as set forth under "PUBLIC OFFER-
    ING PRICE" in Part B of this Prospectus.

(6) The gross underwriting commission of $0.450 per Unit has been calculated
    on the assumption that the Units sold are not subject to a reduction of
    sales charges. In single transactions involving 5,000 Units or more, the
    sales charge is reduced. (See "PUBLIC OFFERING PRICE" in Part B of this
    Prospectus.)


                                      ---
                                      18
<PAGE>

Report of Independent Public Accountants

To the Board of Directors of John Nuveen & Co. Incorporated and Unitholders of
Nuveen Unit Trusts, Series 81:

We have audited the accompanying statements of condition and the schedules of
investments at date of deposit (included in Part A of this Prospectus) of
Nuveen Unit Trusts, Series 81 as of February 17, 2000. These financial state-
ments are the responsibility of the Sponsor. Our responsibility is to express
an opinion on these financial statements based on our audit.

We conducted our audit in accordance with generally accepted auditing stan-
dards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of mate-
rial misstatement. An audit includes examining, on a test basis, evidence sup-
porting the amounts and disclosures in the financial statements. Our proce-
dures included confirmation of the irrevocable letter of credit arrangement
for the purchase of securities, described in Note (2) to the statement of con-
dition, by correspondence with the Trustee. An audit also includes assessing
the accounting principles used and significant estimates made by the Sponsor,
as well as evaluating the overall financial statement presentation. We believe
that our audit provides a reasonable basis for our opinion.

In our opinion, the statements of condition and the schedules of investments
at date of deposit referred to above present fairly, in all material respects,
the financial position of Nuveen Unit Trusts, Series 81, as of February 17,
2000, in conformity with generally accepted accounting principles.

                                                ARTHUR ANDERSEN LLP

Chicago, Illinois

February 17, 2000

                                      ---
                                      19
<PAGE>

                                     {LOGO]

                       NUVEEN UNIT TRUSTS, SERIES 81
                              PROSPECTUS -- PART A

                             February 17, 2000

                              Sponsor       John Nuveen & Co. Incorporated
                                            333 West Wacker Drive
                                            Chicago, IL 60606-1286
                                            Telephone: 312-917-7700


                              Trustee       The Chase Manhattan Bank
                                            4 New York Plaza
                                            New York, NY 10004-2413
                                            Telephone: 800-257-8787

  This Prospectus does not contain complete information about the Portfolio
filed with the Securities and Exchange Commission in Washington, DC under the:

  Securities Act of 1933 (file no. 333-95751)

  Investment Company Act of 1940 (file no. 811-08103)

  To obtain copies at proscribed rates--
    Write: Public Reference Section of the Commission, 450 Fifth Street NW,
           Washington, DC 20549-6009
    Call:  (800) SEC-0330
    Visit: http://www.sec.gov

  No person is authorized to give any information or representation about the
Portfolio not contained in Parts A or B of this Prospectus or the Information
Supplement, and you should not rely on any other information.

  When Units of the Portfolio are no longer available or for investors who will
reinvest into subsequent series of the Portfolio, this Prospectus may be used
as a preliminary Prospectus for a future series. If this is the case, investors
should note the following:

    1. Information in this Prospectus is not complete and may be changed;

    2. We may not sell these securities until the registration statement
  filed with the Securities and Exchange Commission is effective; and

    3. This Prospectus is not an offer to sell the securities of a future
  series and is not soliciting an offer to buy such securities in any state
  where the offer or sale is not permitted.

<PAGE>

[LOGO]

Nuveen Index Portfolio Prospectus

      Prospectus Part B dated February 17, 2000

  The Prospectus for a Nuveen Defined Portfolio (a "Trust") is divided into two
parts. Part A of the Prospectus relates exclusively to a particular Trust or
Trusts and provides specific information regarding each Trust's portfolio,
strategies, investment objectives, expenses, financial highlights, income and
capital distributions, risk factors and optional features. Part B of the
Prospectus provides more general information regarding the Nuveen Defined
Portfolios. You should read both Parts of the Prospectus and retain them for
future reference. Except as provided in Part A of the Prospectus, the
information contained in this Part B will apply to each Trust.

  Additional information about the Trusts is provided in the Information
Supplement. You can receive an Information Supplement by calling The Chase
Manhattan Bank (the "Trustee") at (800) 257-8787.

Nuveen Defined Portfolios

Each Nuveen Defined Portfolio consists of a portfolio of Securities of
companies described in the applicable Part A of the Prospectus (see "Schedule
of Investments" in Part A of the Prospectus for an initial list of the
Securities included in a Trust).

Minimum Investment--$1,000 or 100 Units ($500 or nearest whole number of Units
whose value is less than $500 for IRA purchases), whichever is less.

Redeemable Units. Units of a Trust are redeemable at the offices of the Trustee
at prices based upon the aggregate underlying value of the Securities
(generally determined by the closing sale prices of listed Securities and the
bid prices of over-the-counter traded Securities). During the period ending
with the earlier of six months after the Initial Date of Deposit or the end of
the initial offering period, the Redemption Price per Unit includes estimated
organization costs per Unit. After such period, the Redemption Price will not
include such estimated organization costs. See "Risk/Return Summary--Fees and
Expenses" in Part A of the Prospectus for the organization costs and see
"REDEMPTION" herein for a more detailed discussion of redeeming your Units.

Dividend and Capital Distributions. Cash dividends received by a Trust will be
paid on those dates set forth under "Distributions" in Part A of the
Prospectus. Distributions of funds in the Capital Account, if any, will be made
annually and as part of the final liquidation distribution, if applicable, and
in certain circumstances, earlier. See "DISTRIBUTIONS TO UNITHOLDERS."

Public Offering Price. Public Offering Price of a Trust during the Initial
Offering Period is based upon the aggregate underlying value of the Securities
in the Trust's portfolio (generally determined by the closing sale prices of
the listed Securities and the ask prices of over-the-counter traded Securities)
plus or minus cash, if any, in the Income and Capital Accounts of the Trust,
plus a sales charge as set forth in Part A of the Prospectus, if applicable,
and is rounded to the nearest cent. The Public Offering Price during the period
ending with the earlier of six months after the Initial Date of Deposit or the
end of the initial offering period also includes organization costs incurred in
establishing a Trust. These costs will be deducted from the assets of the Trust
as of the close of such period. See "Risk/Return Summary--Fees and Expenses" in
Part A of the Prospectus. A pro rata share of accumulated dividends, if any, in
the Income Account from the preceding Record Date to, but not including, the
settlement date (normally three business days after purchase) is added to the
Public Offering Price. (See "PUBLIC OFFERING PRICE.")

  The Securities and Exchange Commission has not approved or disapproved these
securities or passed upon the adequacy of this prospectus. Any representation
to the contrary is a criminal offense.
<PAGE>

                               TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                                            Page
                                                                            ----
<S>                                                                         <C>
NUVEEN DEFINED PORTFOLIOS..................................................   3
COMPOSITION OF TRUSTS......................................................   4
THE PORTFOLIOS.............................................................   5
THE NASDAQ 100 INDEX.......................................................   6
NASDAQ(R) 100 INDEX LICENSING AGREEMENT....................................   7
DOW JONES LICENSING AGREEMENT..............................................   8
DOW JONES GLOBAL TITANS INDEX..............................................   9
PUBLIC OFFERING PRICE......................................................  10
MARKET FOR UNITS...........................................................  12
EVALUATION OF SECURITIES AT THE INITIAL DATE OF DEPOSIT....................  12
TAX STATUS.................................................................  13
RETIREMENT PLANS...........................................................  15
TRUST OPERATING EXPENSES...................................................  15
INVESTMENT SUPERVISION.....................................................  16
DISTRIBUTIONS TO UNITHOLDERS...............................................  17
ACCUMULATION PLAN..........................................................  18
REPORTS TO UNITHOLDERS.....................................................  18
UNIT VALUE AND EVALUATION..................................................  18
DISTRIBUTIONS OF UNITS TO THE PUBLIC.......................................  19
OWNERSHIP AND TRANSFER OF UNITS............................................  20
REPLACEMENT OF LOST, STOLEN OR DESTROYED CERTIFICATES......................  20
REDEMPTION.................................................................  21
PURCHASE OF UNITS BY THE SPONSOR...........................................  22
INFORMATION ABOUT THE TRUSTEE..............................................  22
LIMITATIONS ON LIABILITIES OF SPONSOR AND TRUSTEE..........................  22
SUCCESSOR TRUSTEES AND SPONSORS............................................  23
INFORMATION ABOUT THE SPONSOR..............................................  23
INFORMATION ABOUT THE EVALUATOR............................................  24
OTHER INFORMATION..........................................................  24
LEGAL OPINION..............................................................  25
AUDITORS...................................................................  25
SUPPLEMENTAL INFORMATION...................................................  25
</TABLE>

                                       2
<PAGE>

Nuveen Defined Portfolios

  This Nuveen Defined Portfolio is one of a series of separate but similar
investment companies created by the Sponsor, each of which is designated by a
different Series number. The underlying unit investment trust(s) contained in
this Series are combined under one Trust Indenture and Agreement. Specific
information regarding each Trust is set forth in Part A of this Prospectus.
The various Nuveen Defined Portfolios are collectively referred to herein as
the "Trusts." This Series was created under the laws of the State of New York
pursuant to a Trust Indenture and Agreement dated the Initial Date of Deposit
(the "Indenture") between John Nuveen & Co. Incorporated ("Nuveen" or the
"Sponsor") and the Trustee.

  The Sponsor has deposited with the Trustee delivery statements relating to
contracts for the purchase of the securities described in the applicable Part
A of the Prospectus, together with funds represented by an irrevocable letter
of credit issued by a major commercial bank in the amount required for their
purchase (or the securities themselves). See "Schedule of Investments" in Part
A of the Prospectus, for an initial list of the Securities deposited in the
applicable Trust. See also, "Primary Risks" and "Risk Factors" in Part A of
the Prospectus. As used herein, the term "Securities" means the Securities
(including contracts for the purchase thereof) initially deposited in each
Trust and described in the related portfolio and any additional equity
securities that may be held by a Trust.

  The Trustee has delivered to the Sponsor registered Units which represent
ownership of the entire Trust, and which are offered for sale by this
Prospectus. Each Unit of a Trust represents a fractional undivided interest in
the Securities deposited in such Trust. Units may only be sold in states in
which they are registered. To the extent that any Units of any Trust are
redeemed by the Trustee, the aggregate value of the Trust's assets will
decrease by the amount paid to the redeeming Unitholder, but the fractional
undivided interest of each unredeemed Unit in such Trust will increase
proportionately. The Sponsor will initially, and from time to time thereafter,
hold Units in connection with their offering. Units will remain outstanding
until redeemed upon tender to the Trustee by Unitholders, which may include
the Sponsor, or until termination of the Indenture.

  The Trusts employ an indexing strategy and attempt to track the performance
of a specific market index. There can be no assurance that a Trust will be
able to track the performance of an index because it may be impracticable for
the Trust to duplicate or maintain precisely the relative weightings of the
common stocks which comprise the related stock index or to purchase all of
such stocks. Additionally, an investment in Units of the Trusts includes
payment of sales charges, fees and expenses which are not considered in the
total return of the related stock index.

  Additional Units of each Trust may be issued at any time by depositing in
such Trust additional Securities, contracts to purchase additional Securities
together with cash or irrevocable letters of credit, or cash (or a letter of
credit) to be applied to purchase additional Securities. As additional Units
are issued by a Trust as a result of the deposit of additional Securities, the
aggregate value of the Securities in such Trust will be increased and the
fractional undivided interest in such Trust represented by each Unit will be
decreased. If the Sponsor deposits cash (or a letter of credit), existing and
new investors may experience a dilution of their investments and a reduction
in their anticipated income because of fluctuations in the prices of the
Securities between the time of the cash deposit and the purchase of the
Securities and because each Trust will pay the associated brokerage fees. To
minimize this effect, each Trust will attempt to purchase the Securities as
close to the evaluation time or as close to the evaluation prices as possible.
See "COMPOSITION OF TRUSTS" below.

  The Sponsor may realize a profit (or sustain a loss) as of the opening of
business on the Initial Date of Deposit resulting from the difference between
the purchase prices of the Securities and the cost of such Securities to the
Trust, which is based on the evaluation of the Securities as of the opening of
business on the Initial Date of Deposit. (See "Schedule of Investments" in
Part A of the Prospectus.) The Sponsor may also be considered to have realized
a profit or to have sustained a loss, as the case may be, in the amount of any
difference between the cost of the Securities to the Trust (which is based on
the Evaluator's determination of the aggregate value of the underlying
Securities of the Trust) on the subsequent date(s) of deposit and the cost of
such Securities to Nuveen, if applicable.

                                       3
<PAGE>

Composition of Trusts

  Each Trust initially consists of delivery statements relating to contracts
to purchase Securities (or of such Securities) as are listed under "Schedule
of Investments" in Part A of this Prospectus and, thereafter, of such
Securities as may continue to be held from time to time (including certain
Securities deposited in the Trust to create additional Units or in
substitution for Securities not delivered to a Trust.) To assist the Sponsor
in selecting Securities for the Trusts, the Sponsor may use its own resources
to pay outside research service providers.

  On the Initial Date of Deposit, the Sponsor delivered to the Trustee
Securities or contracts for the purchase thereof for deposit in the Trusts.
This initial deposit into each Trust consisted of shares of each of the stocks
which comprise the related stock index. During an initial adjustment period,
the Sponsor will continue to deposit Securities in a Trust (contracts for the
purchase thereof), or cash (or a letter of credit) with instructions to
purchase such Securities, until at the end of such period when the Trust
contains substantially all of the stocks in the related stock index, in
substantially the same weightings as in such index (the "Initial Adjustment
Period"). The Sponsor estimates that the Initial Adjustment Period will last
no longer than 30 days following the Initial Date of Deposit and could last as
little as one day. During the Initial Adjustment Period, the Sponsor intends
to create and maintain a Trust portfolio that generally corresponds to the
index. In connection with any deposit of Securities, purchase and sale
transactions will generally be effected in accordance with a computer
optimization program. (See "THE PORTFOLIOS").

  Precise duplication of the relationship among the Securities in the related
stock index may not be achieved because it may be economically impracticable
or impossible to acquire very small numbers of shares of certain stocks and
because of other procedural policies of the Trusts, but correlation between
the related stock index and each Trust portfolio is expected to be between .97
and .99 over the life of the Trusts. Correlation is a measure of the extent to
which the price of a Trust fluctuates with the price of the index. If a
portfolio held all the securities in the index with exactly the same
weightings as the index at all times, the correlation would be 1.00. Since a
Trust's holdings and weightings will differ for a variety of reasons, the
correlation will be less than 1.00. Although correlation is indirectly related
to performance, it is not a measure of the extent to which the performance of
a Trust will match the performance of the index.

  By investing in those Securities determined by the optimization model in
substantially the same proportions which comprise the related stock index,
each Trust seeks to produce investment results that generally correspond to
the price and yield performance of the equity securities represented by such
index over the terms of such Trust. Due to various factors that include, among
others: (1) price movements of the various Securities will not duplicate one
another, (2) the Sponsor's current intention to purchase shares of the
Securities in round lot quantities only, (3) reinvestment of excess proceeds
not needed to meet redemptions of Units may not be sufficient to acquire equal
round lots of all of the Securities in a Trust and (4) reinvestment of
proceeds received from Securities which are no longer components of the
related stock index might not result in the purchase of an equal number of
shares in any replacement Security, there can be no assurance that this goal
will be satisfied. An investment in Units of a Trust should be made with an
understanding that each Trust includes payments of sales charges, fees and
expenses which may not be considered in public statements of the total return
of the related stock index.

  Each Trust consists of (a) the Securities listed under the related portfolio
that may continue to be held from time to time in such Trust (b) any
additional equity securities acquired and held by such Trust pursuant to the
provisions of the Indenture and (c) any cash held in the Income and Capital
Accounts of such Trust. Neither the Sponsor nor the Trustee shall be liable in
any way for any failure in any of the Securities. However, should any contract
for the purchase of any of the Securities initially deposited hereunder fail,
the Sponsor will, unless substantially all of the moneys held in a Trust to
cover such purchase are reinvested in substitute Securities in accordance with
the Indenture, refund the cash and sales charge attributable to such failed
contract to all Unitholders on the next distribution date.

  Litigation. Except as provided in Part A of the Prospectus, to the best
knowledge of the Sponsor, there is no litigation pending as of the Initial
Date of Deposit in respect of any Securities which might reasonably be
expected to have a material adverse effect on any of the Trusts. It is
possible that after the Initial Date of Deposit, litigation may be initiated
with respect to Securities in any Trust or current litigation may have
unexpected results. The Sponsor is unable to predict whether any such
litigation may have such results or may be instituted, or if instituted,
whether any such litigation might have a material adverse effect on the
Trusts.

                                       4
<PAGE>

  Unitholders will be unable to dispose of any of the Securities in a Trust
and will not be able to vote the Securities. As the holder of the Securities,
the Trustee will have the right to vote all of the voting stocks in a Trust
and will vote such stocks in accordance with the instructions of the Sponsor.

  The value of the Securities will fluctuate over the life of a Trust and may
be more or less than the value at the time they were deposited in such Trust.
The Securities may appreciate or depreciate in value (or pay dividends)
depending on the full range of economic and market influences affecting these
Securities, including the impact of the Sponsor's purchase and sale of
Securities (especially during the primary offering period of Units of a Trust)
and other factors.

  Whether or not the Securities are listed on a securities exchange, the
principal trading market for the Securities may be in the over-the-counter
market. As a result, the existence of a liquid trading market for the
Securities may depend on whether dealers will make a market in the Securities.
There can be no assurance that a market will be made for any of the
Securities, that any market for the Securities will be maintained or of the
liquidity of the Securities in any markets made. In addition, the Trust may be
restricted under the Investment Company Act of 1940 from selling Securities to
the Sponsor. The price at which the Securities may be sold to meet redemptions
and the value of a Trust will be adversely affected if trading markets for the
Securities are limited or absent. There can be no assurance that a Trust will
achieve its investment objectives.

  Legislation. At any time after the Initial Date of Deposit, legislation may
be enacted, with respect to the Securities in a Trust or the issuers of the
Securities. Changing approaches to regulation may have a negative impact on
certain companies represented in a Trust. There can be no assurance that
future legislation, regulation or deregulation will not have a material
adverse effect on a Trust or will not impair the ability of the issuers of the
Securities to achieve their business goals.

The Portfolios

  Each Trust portfolio will consist of as many of the components of the
related stock index as is feasible in order to seek to achieve the respective
Trust's goal of attempting to provide investment results that duplicate
substantially the total return of the index. Following the Initial Adjustment
Period, each Trust is expected to be invested in no less than 95% of the
stocks comprising the related index. Although it may be impracticable for a
Trust to own certain of such stocks at any time, the Sponsor expects to
maintain a correlation between each Trust portfolio and that of the related
index of between .97 and .99. Adjustments to a Trust portfolio will generally
be made on an ongoing basis in accordance with a computer optimization program
which uses a number of factors, including cash flows, risk, historical
correlation between the underlying stocks in the applicable index and the
index itself and transaction costs in an attempt to produce the optimal
correlation with the applicable index. The Trust may invest in new Securities
in several circumstances, that include, in connection with the creation of
additional Units, as companies are dropped from or added to such index, and as
Securities are sold to meet redemptions or to pay for sales charges and
expenses. These adjustments will be made as practicable generally in
accordance with computer program output showing which of the Securities are
under- or over-represented in a Trust portfolio. Adjustments may also be made
from time to time to maintain the appropriate correlation between a Trust and
the related index. The proceeds from any sale may be distributed or invested
in those Securities which the computer program indicates are under-represented
based upon the computer optimization program. See "INVESTMENT SUPERVISION."

  Due to changes in the composition of the applicable index, adjustments to a
Trust portfolio may be made from time to time. It is anticipated that most of
such changes in the applicable indices will occur as a result of merger or ac-
quisition activity. In such cases, a Trust, as a shareholder of an issuer
which is the object of such merger or acquisition activity, will presumably
receive various offers from potential acquirers of the issuer. The Trustee is
not permitted to accept any such offers until such time as the issuer has been
removed from the related index. Since, in most cases, an issuer is removed
from an index only after the consummation of a merger or acquisition, it is
anticipated that the Trusts will generally acquire, in exchange for the stock
of the deleted issuer, the consideration that is being offered to shareholders
of that issuer who have not tendered their shares prior to that time. Any cash
received as consideration in such transactions will generally be reinvested in
the Securities as determined by the computer program output. Any Securities
received as consideration which are not included

                                       5
<PAGE>

in the related index will generally be sold as soon as practicable and will
also generally be reinvested in accordance with the computer optimization pro-
gram.

  The Sponsor does not anticipate purchasing or selling stock in quantities
which are not economically practicable. In addition, certain Securities may
not be available in the quantities specified by the computer program. For
these reasons, among others, precise duplication of the proportionate rela-
tionships in the related index may not be possible. See "INVESTMENT SUPERVI-
SION."

The NASDAQ 100 Index

  The Nasdaq 100 Index represents the largest and most active non-financial
domestic and international issues listed on The Nasdaq Stock Market. Annual
adjustments were first implemented in 1993 when Nasdaq 100 Index options began
trading on the Chicago Board Options Exchange under the symbol "NDX." In April
1996, Nasdaq 100 futures and options on futures began trading on the Chicago
Mercantile Exchange under the ticker "ND."

  All securities in the index are among the top 150 eligible securities based
on closing prices as of October 29, 1999 and the available total shares out-
standing as of November 30, 1999. Nasdaq 100 issues ranked 101 through 150 in
market value will be replaced by larger eligible securities unless the secu-
rity was in the top 100 eligible securities during the previous year's rank-
ing. Eligibility criteria for the index includes a minimum average daily trad-
ing volume of 100,000 shares. Generally, companies also must have seasoned on
Nasdaq or another major exchange, which means they have been listed for a min-
imum of two years. If the security is a foreign security, the company must
have a world wide market value of a least $10 billion, a U.S. market value of
at least $4 billion, and average trading volume of at least 200,000 shares per
day. In addition, foreign securities must be eligible for listed-options trad-
ing.

  Effective December 21, 1998, the Nasdaq 100 Index is calculated based upon a
modified capitalization weighted methodology. To accomplish this, Nasdaq re-
views the composition of the Nasdaq 100 Index on a quarterly basis, and ad-
justs the weightings of index components using a proprietary algorithm whenev-
er: (1) any individual component securities represent more than 24 percent of
the total market value of the index; and/or (2) the combined weight of all se-
curities having individual weightings of at least 4.5 percent exceeds 48 per-
cent of the total market value of the index. The index will be subsequently
readjusted only if the index weights exceed the 24 percent and/or 48 percent
thresholds.

  The precise post-diversification weightings of component securities in the
index was determined based upon closing prices on December 10, 1998. The ag-
gregate weight of the five largest stocks in the index, approximately 61 per-
cent, was scaled down to 40 percent. Weightings of all index securities are
reset by reducing or enlarging such weights toward 1.0 percent, the average
weight. The value of the adjusted index will continue to be disseminated under
the current symbol NDX.

  The Nasdaq-Amex Market Group, which operates The Nasdaq Stock Market is a
subsidiary of the National Association of Securities Dealers, Inc. (NASD(R)),
the largest securities-industry, self-regulatory organization in the United
States.

  The Nasdaq Stock Market lists nearly 5,000 companies, has the largest volume
of trades of any financial market, and trades more shares per day than any
other major U.S. market. Since making its debut as the world's first elec-
tronic stock market, Nasdaq has been at the forefront of innovation, using
technology to bring millions of investors together with the world's leading
companies. It is among the world's best regulated stock markets, employing the
industry's most sophisticated surveillance systems and regulatory specialists
to protect investors and provide a fair and competitive trading environment.

  The following table depicts the Year-End Index Value for the Nasdaq 100
Index from inception (February 1, 1985) through December 31, 1999 as well as
the total returns of the Nasdaq 100 Index, the Standard & Poor's 500 Composite
Stock Price Index ("S&P 500") and the Dow Jones Industrial Average ("DJIA").
The table uses data that is adjusted to reflect that the Nasdaq 100 Index
level was halved on January 3, 1994, and does not

                                       6
<PAGE>

reflect reinvestment of dividends for the Nasdaq 100 Index. Investors should
note that the figures below represent past performance of the Nasdaq 100
Index, S&P 500 and the DJIA and not their future performance or the
performance of the Nasdaq 100 Index Portfolio (which includes certain fees and
expenses). Past performance is, of course, no guarantee of future results.

<TABLE>
<CAPTION>
                                           Year-End  Nasdaq 100 S&P 500  DJIA
                                          Nasdaq 100   Annual   Annual  Annual
Year                                        Value     Returns   Returns Returns
- ----                                      ---------- ---------- ------- -------
<S>                                       <C>        <C>        <C>     <C>
February 1, 1985.........................       125        --       --      --
1985.....................................    132.29      5.83%   31.06%  33.62%
1986.....................................    141.41      6.89%   18.54%  27.25%
1987.....................................    156.25     10.49%    5.67%   5.55%
1988.....................................    177.41     13.54%   16.34%  16.24%
1989.....................................    223.83     26.17%   31.23%  32.24%
1990.....................................    200.53   (10.41)%  (3.14)% (0.54)%
1991.....................................    330.86     64.99%   30.00%  24.25%
1992.....................................    360.19      8.86%    7.43%   7.40%
1993.....................................    398.28     10.57%    9.94%  16.97%
1994.....................................    404.27      1.50%    1.29%   5.02%
1995.....................................    576.23     42.54%   37.11%  36.94%
1996.....................................    821.36     42.54%   22.68%  28.91%
1997.....................................    990.80     20.63%   33.10%  24.91%
1998.....................................  1,836.01     85.31%   28.60%  18.15%
1999.....................................  3,707.83    101.95%   21.04%  27.20%
Average Annual Return Since Nasdaq 100
 Index's Inception.......................               25.51%   18.86%  19.86%
</TABLE>

  The Nasdaq 100 annual returns have been calculated from the year end values.
The S&P 500 annual returns assume that dividends are reinvested as they are
received. The DJIA annual returns assume dividends are reinvested monthly. The
1, 5, and 10 year annual returns for the Nasdaq 100 Index are 101.95%, 55.77%,
and 35.58% respectively. The 1, 5, and 10 year annual returns for the S&P 500
are 21.04%, 28.36%, and 18.04% respectively. The 1, 5, and 10 year annual re-
turns for the DJIA are 27.20%, 27.08%, and 18.38% respectively.

  Because the Nasdaq 100 Index Portfolio is sold to the public at net asset
value plus the applicable sales charge, and the expenses of the Trust are
deducted before making distributions to Unitholders, and because of a variety
of other reasons described in this Prospectus, investment in the Nasdaq 100
Index Portfolio, if it had existed, would have resulted in investment
performance to Unitholders somewhat reduced from that reflected in the above
table.

  Investors should note that the Trusts are not sponsored, endorsed or
promoted by or affiliated with The Nasdaq Stock Market, Inc. and The Nasdaq
Stock Market, Inc. makes no representation, express or implied, to the Trusts
or Unitholders regarding the advisability of investing in an index investment
or unit investment trusts generally or in the Trusts specifically or the
ability of the indexes to track general stock market performance.

NASDAQ 100(R) Index Licensing Agreement

  The Sponsor has entered into a license agreement with The Nasdaq Stock Mar-
ket, Inc. (the "License Agreement"), under which the Nuveen Nasdaq 100 Index
Portfolio (the "Nasdaq 100 Portfolio") (through the Sponsor) is granted a li-
cense to use the trademarks, service marks and trade names "Nasdaq," "Nasdaq
100," and "Nasdaq 100 Index" solely in materials relating to the creation and
issuance, marketing and promotion of the Trust and in accordance with any ap-
plicable federal and state securities law to indicate the source of the Nasdaq
100 Index as a basis for determining the composition of the Trust's portfolio.
As consideration for the grant of the license, the Trust will pay to The
Nasdaq Stock Market, Inc. an annual fee. If the Nasdaq 100 Index ceases to be
compiled or made available or the anticipated correlation between the Trust
and the Nasdaq 100 Index is not maintained, the Sponsor may direct that the
Trust continue to be operated using the Nasdaq 100 Index as it existed on the
last date on which it was available or may direct that the Indenture be termi-
nated.

                                       7
<PAGE>

  Neither the Trust nor the Unitholders are entitled to any rights whatsoever
under the foregoing licensing arrangements or to use any of the covered trade-
marks or to use the Nasdaq 100 Index, except as specifically described herein
or as may be specified in the Indenture or the License Agreement.

  The Trust is not sponsored, endorsed, sold or promoted by The Nasdaq Stock
Market, Inc. (including its affiliates) (the "Corporations"). The Corporations
have not passed on the legality or suitability of, or the accuracy or adequacy
of descriptions and disclosures relating to, the Nasdaq 100 Portfolio or Units
of the Nasdaq 100 Portfolio. The Corporations make no representation or war-
ranty, express or implied to the owners of Units of the Nasdaq 100 Portfolio
or any member of the public regarding the advisability of investing in Securi-
ties generally or in Units of the Nasdaq 100 Portfolio particularly or the
ability of the Nasdaq 100 Index to track general stock market performance. The
Corporations' only relationship to the Sponsor ("Licensee") and the Nasdaq 100
Portfolio is in the licensing of certain trademarks, service marks, and trade
names of the Corporations and the use of the Nasdaq 100 Index which is deter-
mined, composed and calculated by Nasdaq without regard to the Licensee, the
Nasdaq 100 Portfolio or Unitholders of the Nasdaq 100 Portfolio. Nasdaq has no
obligation to take the needs of the Licensee or the owners of the Nasdaq 100
Portfolio into consideration in determining, composing or calculating the
Nasdaq 100 Index. The Corporations are not responsible for and have not par-
ticipated in the determination of the timing, prices, or quantities of the
Units of the Nasdaq 100 Portfolio to be issued or in the determination or cal-
culation of the equation by which the Units of the Nasdaq 100 Portfolio are to
be converted into cash. The Corporations have no liability in connection with
the administration of the Nasdaq 100 Portfolio, marketing or trading of Units
of the Nasdaq 100 Portfolio.

  THE CORPORATIONS DO NOT GUARANTEE THE ACCURACY AND/OR UNINTERRUPTED
CALCULATION OF THE NASDAQ 100 INDEX OR ANY DATA INCLUDED THEREIN. THE
CORPORATIONS MAKE NO WARRANTY, EXPRESS OR IMPLIED, AS TO RESULTS TO BE
OBTAINED BY LICENSEE, OWNERS OF UNITS OF THE NASDAQ 100 PORTFOLIO, OR ANY
OTHER PERSON OR ENTITY FROM THE USE OF THE NASDAQ 100 INDEX OR ANY DATA
INCLUDED THEREIN. THE CORPORATIONS MAKE NO EXPRESS OR IMPLIED WARRANTIES, AND
EXPRESSLY DISCLAIM ALL WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A
PARTICULAR PURPOSE OR USE WITH RESPECT TO THE NASDAQ 100 INDEX OR ANY DATA
INCLUDED THEREIN. WITHOUT LIMITING ANY OF THE FOREGOING, IN NO EVENT SHALL THE
CORPORATIONS HAVE ANY LIABILITY FOR ANY LOST PROFITS OR SPECIAL, INCIDENTAL,
PUNITIVE, INDIRECT, OR CONSEQUENTIAL DAMAGES, EVEN IF NOTIFIED OF THE
POSSIBILITY OF SUCH DAMAGES.

Dow Jones Licensing Agreement

  The Sponsor has entered into a license agreement with Dow Jones & Company,
Inc. ("Dow Jones") (the "License Agreement"), under which the Dow Jones Global
Titans IndexSM Portfolio (the "Global Titans Portfolio") (through the Sponsor)
is granted a license to use the trademarks, service marks and trade names Dow
Jones Industrial AverageSM, DJIASM, Dow Jones Global Titans IndexSM and
DJInetSM solely in materials relating to the creation and issuance, marketing
and promotion of the Global Titans Portfolio and in accordance with any
applicable federal and state securities law to indicate the source of the
indices as a basis for determining the composition of the Global Titans
Portfolio's portfolio. As consideration for the grant of the license, the
Global Titans Portfolio will pay to Dow Jones an annual fee. If an index
ceases to be compiled or made available or the anticipated correlation between
the Global Titans Portfolio and such index is not maintained, the Sponsor may
direct that the Global Titans Portfolio continue to be operated using the
index as it existed on the last date on which it was available or may direct
that the Indenture be terminated.

  Neither the Global Titans Portfolio nor the Unitholders are entitled to any
rights whatsoever under the foregoing licensing arrangements or to use any of
the covered trademarks or to use the indices, except as specifically described
herein or as may be specified in the Indenture or the License Agreement.

  The Global Titans Portfolio is not sponsored, endorsed, sold or promoted by
Dow Jones. Dow Jones makes no representation or warranty, express or implied,
to the owners of the Global Titans Portfolio or any member of the public re-
garding the advisability of investing in securities generally or in the Global
Titans Portfolio particularly. Dow Jones' only relationship to the Licensee is
the licensing of certain trademarks, trade names and service marks of Dow
Jones and of the Dow Jones Global Titans Index which are determined, composed
and calculated by Dow Jones without regard to the Licensee or the Global Ti-
tans Portfolio. Dow Jones has no obligation to

                                       8
<PAGE>


take the needs of the Licensee or the owners of the Global Titans Portfolio
into consideration in determining, composing or calculating the Dow Jones
Global Titans Index. Dow Jones is not responsible for and has not participated
in the determination of the timing of, prices at, or quantities of the Global
Titans Portfolio to be issued or in the determination or calculation of the
equation by which the Global Titans Portfolio is to be converted into cash.
Dow Jones has no obligation or liability in connection with the administra-
tion, marketing or trading of the Global Titans Portfolio.

  DOW JONES DOES NOT GUARANTEE THE ACCURACY AND/OR THE COMPLETENESS OF THE DOW
JONES GLOBAL TITANS INDEX OR ANY DATA INCLUDED THEREIN AND DOW JONES SHALL
HAVE NO LIABILITY FOR ANY ERRORS, OMISSIONS, OR INTERRUPTIONS THEREIN. DOW
JONES MAKES NO WARRANTY, EXPRESS OR IMPLIED, AS TO RESULTS TO BE OBTAINED BY
THE LICENSEE, OWNERS OF THE GLOBAL TITANS PORTFOLIO, OR ANY OTHER PERSON OR
ENTITY FROM THE USE OF THE DOW JONES GLOBAL TITANS INDEX OR ANY DATA INCLUDED
THEREIN. DOW JONES MAKES NO EXPRESS OR IMPLIED WARRANTIES, AND EXPRESSLY
DISCLAIMS ALL WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR
PURPOSE OR USE WITH RESPECT TO THE DOW JONES GLOBAL TITANS INDEX OR ANY DATA
INCLUDED THEREIN. WITHOUT LIMITING ANY OF THE FOREGOING, IN NO EVENT SHALL DOW
JONES HAVE ANY LIABILITY FOR ANY LOST PROFITS OR INDIRECT, PUNITIVE, SPECIAL
OR CONSEQUENTIAL DAMAGES OR LOSSES, EVEN IF NOTIFIED OF THE POSSIBILITY
THEREOF.

Dow Jones Global Titans Index

  Among today's many different investment philosophies and trading strategies,
two are becoming increasingly popular. The first is the move toward large, es-
pecially blue-chip, stocks: one example of this phenomenon was investors' so-
called "Flight to Quality" in 1998 amid global financial turbulence. Market
leaders are favored by investors for their stability: corporate giants with
financial strength and market dominance usually exhibit lower volatility.
Moreover, large-cap stocks have significantly outperformed the broad market
over the past decade.

  The second growing trend is the move toward global markets. More investors
are seeking to capitalize on the benefits of investing globally, in part be-
cause after a nine-year continuous expansion of the U.S. economy, many ana-
lysts now predict that the greatest opportunities lie abroad.

  With these trends in mind, Dow Jones Indexes sought to create an index whose
constituents meet the following criteria: stable earnings potential, broad
global exposure, and relatively low risk and price volatility, particularly in
times of market corrections and downturns. The Dow Jones Global Titans Index
was developed in response to these needs. The 50 constituents of this new in-
dex are some of the world's most well known and well established blue-chip
companies, and provide considerable exposure to global markets.

  The major characteristics and key benefits of the Dow Jones Global Titans
Index can be summarized into the following nine points:

  1. Market leadership

  2. Multinational exposure

  3. Global diversification

  4. High liquidity

  5. Low turnover

  6. Sufficient Market coverage

  7. Competitive performance

  8. Independent characteristics

  9. Systematic procedures

Dow Jones Global Titans Index Selection Process:

1. The Dow Jones Global Index (DJGI) serves as the Universe, or Initial Pool,
   for the Dow Jones Global Titans Index. Using the DJGI as the Initial Pool
   assures sufficient distribution of stocks across countries, regions, eco-
   nomic sectors and industry groups.

                                       9
<PAGE>


2. All companies in the Initial Pool are sorted in descending order by
   weighted average market value. The weighted average market value is calcu-
   lated with respect to data for the past four quarters, giving the greatest
   weight to the most recent quarter: a weight of 4 is assigned to the most
   recent quarter, 3 to the previous quarter, etc.

3. From the weighted average market value ranking, the top 100 companies are
   selected to comprise the Final Pool.

4. Eliminated from the Final Pool are any companies that clearly are not
   "Global"--those that do not generate any revenue from foreign markets.

5. Companies remaining in the Final Pool are ranked separately by each of five
   fundamental measures: assets, book value, sales/revenue, net profit and
   foreign sales.

6. A final ranking of the companies in the Final Pool is generated by equally
   weighting each of the five fundamental measure rankings and the weighted
   average market cap ranking. To break any ties in the final ranking, the
   weighted average market value ranking is used.

7. From the final ranking, the top 50 stocks are selected as Index Components.
   A capitalization-weighted approach is used to calculate the index value.

Public Offering Price

  The Public Offering Price of the Units is based on the aggregate underlying
value of the Securities in a Trust (generally determined by the closing sale
prices of listed Securities and the ask prices of over-the-counter traded
Securities), plus or minus cash, if any, in the Income and Capital Accounts of
the Trust. If Units are purchased after the first deferred sales charge
payment specified in "Risk/Return Summary--Fees and Expenses"

in Part A of the Prospectus, the Public Offering Price includes an upfront
sales charge equal to the difference between the maximum sales charge (as set
forth in Part A of the Prospectus) per Unit and the maximum remaining deferred
sales charge (as set forth in Part A of the Prospectus) and is rounded to the
nearest cent. In addition, a portion of the Public Offering Price during the
initial offering period also consists of Securities in an amount sufficient to
pay for all or a portion of the costs incurred in establishing a Trust,
including costs of preparing the registration statement, the trust indenture
and other closing documents, registering Units with the Securities and
Exchange Commission and states, the initial audit of each Trust portfolio, the
initial evaluation, legal fees, the initial fees and expenses of the Trustee
and any non-material out-of-pocket expenses.

  The Securities purchased with the portion of the Public Offering Price
intended to be used to reimburse the Sponsor for the Trust's organization
costs will be purchased in the same proportionate relationship as all the
Securities contained in the Trust. Securities will be sold to reimburse the
Sponsor for the Trust's organization costs at the earlier of six months after
the Initial Date of Deposit or the end of the initial offering period (a
significantly shorter time period than the life of the Trust). During the
period ending with the earlier of six months after the Initial Date of Deposit
or the end of the initial offering period, there may be a decrease in the
value of the Securities. To the extent the proceeds from the sale of these
Securities are insufficient to repay the Sponsor for the Trust organization
costs, the Trustee will sell additional Securities to allow the Trust to fully
reimburse the Sponsor. In that event, the net asset value per Unit will be
reduced by the amount of additional Securities sold. Although the dollar
amount of the reimbursement due to the Sponsor will remain fixed and will
never exceed the amount per Unit set forth for the Trusts in "Statement of
Condition," this will result in a greater effective cost per Unit to
Unitholders for the reimbursement to the Sponsor. See "Risk/Return Summary--
Fees and Expenses" in Part A of the Prospectus.

  Commencing on those dates set forth under "Risk/Return Summary--Fees and
Expenses" in Part A of this Prospectus, a deferred sales charge in an amount
described in Part A of the Prospectus will be assessed per Unit per applicable
month. The deferred sales charges will be paid from funds in the Capital
Account, if sufficient, or

from the periodic sale of Securities. A pro rata share of accumulated
dividends, if any, in the Income Account from the preceding Record Date to,
but not including, the settlement date (normally three business days after
purchase) is added to the Public Offering Price. The total maximum sales
charge assessed to Unitholders on a per Unit basis will be the amount set
forth in "Risk/Return Summary--Fees and Expenses" in Part A of the Prospectus.
See "UNIT VALUE AND EVALUATION."

                                      10
<PAGE>

  The sales charge applicable to quantity purchases is reduced on a graduated
scale as set forth in Part A of this Prospectus. For purposes of calculating
the applicable sales charge, purchasers who have indicated their intent to
purchase a specified amount of Units of any Nuveen unit investment trust in
the primary or secondary offering period by executing and delivering a letter
of intent to the Sponsor, which letter of intent must be in a form acceptable
to the Sponsor and shall have a maximum duration of thirteen months, will be
eligible to receive a reduced sales charge according to the graduated scale
provided in Part A of this Prospectus, based on the amount of intended
aggregate purchases as expressed in the letter of intent. For purposes of
letter of intent calculations, units of equity products are valued at $10 per
unit. Due to administrative limitations and in order to permit adequate
tracking, the only secondary market purchases that will be permitted to be
applied toward the intended specified amount and that will receive the
corresponding reduced sales charge are those Units that are acquired through
or from the Sponsor. By establishing a letter of intent, a Unitholder agrees
that the first purchase of Units following the execution of such letter of
intent will be at least 5% of the total amount of the intended aggregate
purchases expressed in such Unitholder's letter of intent. Further, through
the establishment of the letter of intent, such Unitholder agrees that Units
representing 5% of the total amount of the intended purchases will be held in
escrow by the Trustee pending completion of these purchases. All distributions
on Units held in escrow will be credited to such Unitholder's account. If
total purchases prior to the expiration of the letter of intent period equal
or exceed the amount specified in a Unitholder's letter of intent, the Units
held in escrow will be transferred to such Unitholder's account. A Unitholder
who purchases Units during the letter of intent period in excess of the number
of Units specified in a Unitholder's letter of intent, the amount of which
would cause the Unitholder to be eligible to receive an additional sales
charge reduction, will be allowed such additional sales charge reduction on
the purchase of Units which caused the Unitholder to reach such new breakpoint
level and on all additional purchases of Units during the letter of intent
period. If the total purchases are less than the amount specified, the
Unitholder involved must pay the Sponsor an amount equal to the difference
between the amounts paid for these purchases and the amounts which would have
been paid if the higher sales charge had been applied; the Unitholder will,
however, be entitled to any reduced sales charge qualified for by reaching any
lower breakpoint level. If such Unitholder does not pay the additional amount
within 20 days after written request by the Sponsor or the Unitholder's
securities representative, the Sponsor will instruct the Trustee to redeem an
appropriate number of the escrowed Units to meet the required payment. By
establishing a letter of intent, a Unitholder irrevocably appoints the Sponsor
as attorney to give instructions to redeem any or all of such Unitholder's
escrowed Units, with full power of substitution in the premises. A Unitholder
or his securities representative must notify the Sponsor whenever such
Unitholder makes a purchase of Units that he wishes to be counted towards the
intended amount.

  Pursuant to the terms of the Indenture, the Trustee may terminate a Trust if
the net asset value of such Trust, as shown by any evaluation, is less than
20% of the total value of the Securities deposited in the Trust during the
primary offering period of the Trust.

  At all times while Units are being offered for sale, the Trustee will
appraise or cause to be appraised daily the value of the underlying Securities
in each Trust as of 4:00 p.m. eastern time, or as of any earlier closing time
on a day on which the New York Stock Exchange (the "Exchange") is scheduled in
advance to close at such earlier time and will adjust the Public Offering
Price of the Units commensurate with such appraisal ("Evaluation Time"). Such
Public Offering Price will be effective for all orders received by a dealer or
the Sponsor at or prior to 4:00 p.m. eastern time on each such day or as of
any earlier closing time on a day on which the Exchange is scheduled in
advance to close at such earlier time. Orders received after that time, or on
a day when the Exchange is closed for a scheduled holiday or weekend, will be
held until the next determination of price.

  The graduated sales charges set forth in the table provided in Part A of
this Prospectus will apply on all applicable purchases of Nuveen investment
company securities on any one day by the same purchaser in the amounts stated,
and for this purpose purchases of a Trust will be aggregated with concurrent
purchases of any other Nuveen unit investment trust or of shares of any open-
end management investment company of which the Sponsor is principal
underwriter and with respect to the purchase of which a sales charge is
imposed. Purchases by or for the account of individuals and their spouses,
parents, children, grandchildren, grandparents, parents-in-law, sons- and
daughters-in-law, siblings, a sibling's spouse and a spouse's siblings
("immediate family members") will be aggregated to determine the applicable
sales charge. The graduated sales charges are also applicable to a trustee or
other fiduciary purchasing securities for a single trust estate or single
fiduciary account.

  Units may be purchased with the applicable reduced sales charge provided for
"Wrap Account Purchases" under "How to Buy and Sell Units" in Part A of the
Prospectus or herein by (1) investors who purchase Units

                                      11
<PAGE>


through registered investment advisers, certified financial planners and
registered broker-dealers who in each case either charge periodic fees for
financial planning, investment advisory or asset management services, or
provide such services in connection with the establishment of an investment
account for which a comprehensive "wrap fee" charge is imposed, (2) bank trust
departments investing funds over which they exercise discretionary investment
authority and that are held in a fiduciary, agency, custodial or similar
capacity, (3) any person who for at least 90 days, has been an officer,
director or bona fide employee of any firm offering Units for sale to
investors, (4) officers and directors of bank holding companies that make
Units available directly or through subsidiaries or bank affiliates, and (5)
officers or directors and bona fide, full-time employees of Nuveen, Nuveen
Advisory Corp., Nuveen Institutional Advisory Corp., Rittenhouse Financial
Services, Inc., The John Nuveen Company, and Dow Jones & Company, Inc. ("Dow
Jones"), including in each case these individuals and their spouses, children,
parents and spouses' parents, however, purchases by parents, individuals
associated with Dow Jones, and adult children who are not members of the
household of the officers, directors or full-time employees described above,
must be made through a registered broker-dealer and (6) any person who for at
least 90 days, has been an officer, director or bona fide employee of any
vendor who provides services to the Sponsor and who purchases Units through a
registered broker-dealer (collectively, the "Discounted Purchases").
Notwithstanding anything to the contrary in this Prospectus, investors who
purchase Units as described in this paragraph will not receive sales charge
reductions for quantity purchases.

  Whether or not Units are being offered for sale, the Trustee will determine
or cause to be determined the aggregate value of each Trust as of 4:00 p.m.
eastern time: (i) on each June 30 or December 31 (or, if such date is not a
business day, the last business day prior thereto), (ii) on any day on which a
Unit is tendered for redemption (or the next succeeding business day if the
date of tender is a non-business day) and (iii) at such other times as may be
necessary. For this purpose, a "business day" shall be any day on which the
Exchange is normally open. (See "UNIT VALUE AND EVALUATION.")

Market for Units

  During the initial public offering period, the Sponsor intends to offer to
purchase Units of each Trust at a price based upon the pro rata share per Unit
of the aggregate underlying value of the Securities in such Trust (generally
determined by the closing sale prices of listed Securities and the ask prices
of over-the-counter traded Securities). Afterward, although it is not
obligated to do so, the Sponsor may maintain a secondary market for Units of
each Trust at its own expense and continuously offer to purchase Units of each
Trust at prices, subject to change at any time, which are based upon the
aggregate underlying value of the Securities in a Trust (generally determined
by the closing sale prices of listed Securities and the bid prices of over-
the-counter traded Securities). During the period ending with the earlier of
six months after the Initial Date of Deposit or the end of the initial
offering period, the price at which the Sponsor expects to repurchase Units
(the "Sponsor's Repurchase Price") includes estimated organization costs per
Unit. After such period, the Sponsor's Repurchase Price will not include such
estimated organization costs. See "Risk/Return Summary--Fees and Expenses" in
Part A of the Prospectus. Unitholders who wish to dispose of their Units
should inquire of the Trustee or their broker as to the current Redemption
Price. Units subject to a deferred sales charge which are sold or tendered for
redemption prior to such time as the entire deferred sales charge on such
Units has been collected will be assessed the amount of the remaining deferred
sales charge at the time of sale or redemption.

  Certificates, if any, for Units are delivered to the purchaser as promptly
after the date of settlement (three business days after purchase) as the
Trustee can complete the mechanics of registration, normally within 48 hours
after registration instructions are received. Purchasers of Units to whom
Certificates are issued will be unable to exercise any right of redemption
until they have received their Certificates, properly endorsed for transfer.
(See "REDEMPTION.")

Evaluation of Securities at the Initial Date of Deposit

  The prices at which the Securities deposited in the Trusts would have been
offered to the public on the business day prior to the Initial Date of Deposit
were determined by the Trustee.

  The amount by which the Trustee's determination of the aggregate value of
the Securities deposited in the Trusts was greater or less than the cost of
such Securities to the Sponsor was profit or loss to the Sponsor. (See Part A
of this Prospectus.) The Sponsor also may realize further profit or sustain
further loss as a result of

                                      12
<PAGE>

fluctuations in the Public Offering Price of the Units. Cash, if any, made
available to the Sponsor prior to the settlement date for a purchase of Units,
or prior to the acquisition of all Portfolio securities by a Trust, may be
available for use in the Sponsor's business, and may be of benefit to the
Sponsor.

Tax Status

  Each Trust has elected and intends to qualify on a continuing basis for
special federal income tax treatment as a "regulated investment company" under
the Internal Revenue Code of 1986, as amended (the "Code"). If a Trust so
qualifies and timely distributes to Unitholders 90% or more of its taxable
income (without regard to its net capital gain, i.e., the excess of its net
long-term capital gain over its net short-term capital loss), it will not be
subject to Federal income tax on the portion of its taxable income (including
any net capital gain) that it distributes to Unitholders. In addition, to the
extent a Trust timely distributes to Unitholders at least 98% of its taxable
income (including any net capital gain), it will not be subject to the 4%
excise tax on certain undistributed income of "regulated investment
companies." Because the Trusts intend to timely distribute their taxable
income (including any net capital gain), it is anticipated that the Trusts
will not be subject to Federal income tax or the excise tax.

  Distributions to Unitholders of a Trust's income, other than distributions
which are designated as capital gain dividends, will be taxable as ordinary
income to Unitholders, except that to the extent that distributions to a
Unitholder in any year exceed the Trust's current and accumulated earnings and
profits, they will be treated as a return of capital and will reduce the
Unitholder's basis in his Units and, to the extent that they exceed his basis,
will be treated as a gain from the sale of his Units as discussed below. Al-
though distributions generally will be treated as distributed when paid, dis-
tributions declared in October, November or December, payable to Unitholders
of record on a specified date in one of those months and paid during January
of the following year will be treated as having been distributed by a Trust
(and received by the Unitholders) on December 31 of the year such distribu-
tions are declared.

  Distributions of a Trust's net capital gain which are properly designated as
capital gain dividends by the Trust will be taxable to Unitholders as long-
term capital gain, regardless of the length of time the Units have been held
by a Unitholder. A Unitholder may recognize a taxable gain or loss if the
Unitholder sells or redeems his Units. Any gain or loss arising from (or
treated as arising from) the sale or redemption of Units will generally be a
capital gain or loss, except in the case of a dealer or a financial institu-
tion. The Internal Revenue Service Restructuring and Reform Act of 1998 (the
"1998 Tax Act") provides that for taxpayers other than corporations, net capi-
tal gain (which is defined as net long-term capital gain over net short-term
capital loss for the taxable year) realized from property (with certain exclu-
sions) is generally subject to a maximum marginal stated tax rate of 20% (10%
in the case of certain taxpayers in the lowest tax bracket). Capital gain or
loss is long-term if the holding period for the asset is more than one year,
and is short-term if the holding period for the asset is one year or less. The
date on which a Unit is acquired (i.e., the "trade date") is excluded for pur-
poses for determining the holding period of the Unit. Capital gains realized
from assets held for one year or less are taxed at the same rates as ordinary
income. Note that if a Unitholder holds Units for six months or less and sub-
sequently sells such Units at a loss, the loss will be treated as a long-term
capital loss to the extent that any long-term capital gain distribution is
made with respect to such Units during the six-month period or less that the
Unitholder owns the Units.

  The Taxpayer Relief Act of 1997 includes provisions that treat certain
transactions designed to reduce or eliminate risk of loss and opportunities
for gain (e.g., short sales, offsetting notional principal contracts, futures
or forward contracts or similar transactions) as constructive sales for pur-
poses of recognition of gain (but not loss) and for purposes of determining
the holding period. Unitholders should consult their own tax advisers with re-
gard to any such constructive sales rules.

  In addition, it should be noted that capital gains may be recharacterized as
ordinary income in the case of certain financial transactions that are consid-
ered "conversion transactions" effective for transactions entered into after
April 30, 1993. Unitholders and prospective investors should consult with
their tax advisers regarding the potential effect of this provision on their
investment in Units.

  Generally, the tax basis of a Unitholder includes sales charges, and such
charges are not deductible. A portion of the sales charge for the Trust is de-
ferred. It is possible that for federal income tax purposes a portion

                                      13
<PAGE>

of the deferred sales charge may be treated as interest which would be deduct-
ible by a Unitholder subject to limitations on the deduction of investment in-
terest. In such case, the non-interest portion of the deferred sales charge
would be added to the Unitholder's tax basis in his Units. In any case the in-
come (or proceeds from redemption) a Unitholder must take into account for
federal income tax purposes is not reduced by amounts deducted to pay the de-
ferred sales charge.

  Distributions which are taxable as ordinary income to Unitholders will con-
stitute dividends for federal income tax purposes. When Units are held by cor-
porate Unitholders, Trust distributions may qualify for the 70% dividends-re-
ceived deduction, subject to the limitations otherwise applicable to the
availability of the deduction, to the extent the distribution is attributable
to dividends received by a Trust from United States corporations (other than
real estate investment trusts) and is designated by a Trust as being eligible
for such deduction. To the extent dividends received by a Trust are attribut-
able to foreign corporations, a corporation that owns Units will not be enti-
tled to the dividends-received deduction with respect to its pro rata portion
of such dividends, since the dividends-received deduction is generally avail-
able only with respect to dividends paid by domestic corporations. Each Trust
will provide each Unitholder with information annually concerning what part of
the Trust's distributions are eligible for the dividends received deduction.

  The Trust may elect to pass through to the Unitholders the foreign income
and similar taxes paid by the Trust in order to enable such Unitholders to
take a credit (or deduction) for foreign income taxes paid by the Trust. If
such an election is made, Unitholders of the Trust, because they are deemed to
own a pro rata portion of the foreign securities held by the Trust, must in-
clude in their gross income, for federal income tax purposes, both their por-
tion of dividends received by the Trust and also their portion of the amount
which the Trust deems to be the Unitholders' portion of foreign income taxes
paid with respect to, or withheld from, dividends, interest or other income of
the Trust from its foreign investments. Unitholders may then subtract from
their federal income tax the amount of such taxes withheld, or else treat such
foreign taxes as deductions from gross income; however, as in the case of in-
vestors receiving income directly from foreign sources, the above described
tax credit or deduction is subject to certain limitations. The 1997 Act im-
poses a required holding period for such credits. Unitholders should consult
their tax advisers regarding this election and its consequences to them.

  Under the Code, certain miscellaneous itemized deductions, such as invest-
ment expenses, tax return preparation fees and employee business expenses,
will be deductible by individuals only to the extent they exceed 2% of ad-
justed gross income. Miscellaneous itemized deductions subject to this limita-
tion under present law do not include expenses incurred by the Trust so long
as the Units of a Trust are held by or for 500 or more persons at all times
during the taxable year or another exception is met. In the event the Units of
a Trust are held by fewer than 500 persons, additional taxable income may be
realized by the individual (and other noncorporate) Unitholders in excess of
the distributions received from the Trust.

  Distributions reinvested into additional Units of a Trust will be taxed to a
Unitholder in the manner described above (i.e., as ordinary income, long-term
capital gain or as a return of capital).

  Under certain circumstances a Unitholder may be able to request an in kind
distribution upon termination of the Trust. See "Redemption." Unitholders
electing an in kind distribution of shares of Securities should be aware that
the exchange is subject to taxation and Unitholders will recognize gain or
loss (subject to various nonrecognition provisions under the Code) based on
the value of the Securities received. Investors electing an in kind distribu-
tion should consult their own tax advisers with regard to such transaction.

  The federal tax status of each year's distributions will be reported to
Unitholders and to the Internal Revenue Service. Each Unitholder will be re-
quested to provide the Unitholder's taxpayer identification number to the
Trustee and to certify that the Unitholder has not been notified that payments
to the Unitholder are subject to back-up withholding. If the proper taxpayer
identification number and appropriate certification are not provided when re-
quested, distributions by the Trust to such Unitholder (including amounts re-
ceived upon the redemption of Units) will be subject to back-up withholding.

  The foregoing discussion relates only to the federal income tax status of
the Trusts and to the tax treatment of distributions by a Trust to United
States Unitholders.

  A Unitholder who is a foreign investor (i.e., an investor other than a
United States citizen or resident or a United States corporation, partnership,
estate or trust) should be aware that, generally, subject to applicable tax

                                      14
<PAGE>

treaties, distributions from a Trust which constitute dividends for Federal
income tax purposes (other than dividends which a Trust designates as capital
gain dividends) will be subject to United States income taxes, including with-
holding taxes. However, distributions received by a foreign investor from a
Trust that are designated by the Trust as capital gain dividends should not be
subject to United States Federal income taxes, including withholding taxes, if
all of the following conditions are met: (i) the capital gain dividend is not
effectively connected with the conduct by the foreign investor of a trade or
business within the United States, (ii) the foreign investor (if an individu-
al) is not present in the United States for 183 days or more during his or her
taxable year, and (iii) the foreign investor provides all certification which
may be required of his status (foreign investors may contact the Sponsor to
obtain a Form W-8 which must be filed with the Trustee and refiled every three
calendar years thereafter). Foreign investors should consult their tax advi-
sors with respect to United States tax consequences of ownership of Units.
Units in a Trust and Trust distributions may also be subject to state and lo-
cal taxation and Unitholders should consult their tax advisors in this regard.

  Unitholders desiring to purchase Units for tax-deferred plans and IRAs
should consult their broker-dealers for details on establishing such accounts.
Units may also be purchased by persons who already have self-directed plans
established.

Retirement Plans

  Units of the Trusts may be well suited for purchase by Individual Retirement
Accounts, Keogh Plans, pension funds and other tax-deferred retirement plans.
Generally the Federal income tax relating to capital gains and income received
in each of the foregoing plans is deferred until distributions are received.
Distributions from such plans are generally treated as ordinary income but
may, in some cases, be eligible for special averaging or tax-deferred rollover
treatment. Investors considering participation in any such plan should review
specific tax laws related thereto and should consult their attorneys or tax
advisers with respect to the establishment and maintenance of any such plan.
Such plans are offered by brokerage firms and other financial institutions.
Fees and charges with respect to such plans may vary.

Trust Operating Expenses

  No annual advisory fee is charged to the Trusts by the Sponsor. The Sponsor
and/or its affiliates do, however, receive an annual fee as set forth in
"Risk/Return Summary--Fees and Expenses" in Part A of the Prospectus for
maintaining surveillance over the portfolio and for performing certain
administrative services for the Trusts (the "Sponsor's Supervisory Fee"). In
providing such supervisory services, the Sponsor may purchase research from a
variety of sources, which may include dealers of the Trusts. If so provided in
Part A of the Prospectus, the Sponsor may also receive an annual fee for
providing bookkeeping and administrative services for a Trust (the
"Bookkeeping and Administrative Fee"). Such services include, but are not
limited to, the preparation of comprehensive tax statements and providing
account information to the Unitholders. If so provided in Part A of the
Prospectus, the Evaluator may also receive an annual fee for performing
evaluation services for the Trusts (the "Evaluator's Fee"). In addition, if so
provided in Part A of the Prospectus, a Trust may be charged an annual
licensing fee to cover licenses for the use of service marks, trademarks and
trade names and/or for the use of databases and research. Estimated annual
Trust expenses are as set forth in Part A of this Prospectus; if actual
expenses are higher than the estimate, the excess will be borne by the Trust.
The estimated expenses do not include the brokerage commissions and other
transactional fees payable by the Trust in purchasing and selling Securities.

  The Trustee receives for ordinary recurring services an annual fee for each
Trust as set forth in "Risk/Return Summary--Fees and Expenses" appearing in
Part A of this Prospectus. The Trustee's Fee may be periodically adjusted in
response to fluctuations in short-term interest rates (reflecting the cost to
the Trustee of advancing funds to a Trust to meet scheduled distributions). In
addition, the Sponsor's Supervisory Fee, Bookkeeping and Administrative Fee,
Evaluator's Fee and the Trustee's Fee may be adjusted in accordance with the
cumulative percentage increase of the United States Department of Labor's
Consumer Price Index entitled "All Services Less Rent of Shelter" since the
establishment of the Trusts. In addition, with respect to any fees payable to
the Sponsor or an affiliate of the Sponsor for providing bookkeeping and other
administrative services, supervisory services and evaluation services, such
individual fees may exceed the actual costs of providing such services for a
Trust, but at no time will the total amount received for such services, in the
aggregate, rendered to all unit investment trusts of which John Nuveen & Co.
Incorporated is the Sponsor in any calendar year exceed the actual

                                      15
<PAGE>

cost to the Sponsor or its affiliates of supplying such services, in the
aggregate, in such year. The Trustee has the use of funds, if any, being held
in the Income and Capital Accounts of each Trust for future distributions,
payment of expenses and redemptions. These Accounts are non-interest bearing
to Unitholders. Pursuant to normal banking procedures, the Trustee benefits
from the use of funds held therein. Part of the Trustee's compensation for its
services to the Trusts is expected to result from such use of these funds.

  The following are additional expenses of the Trusts and, when paid by or are
owed to the Trustee, are secured by a lien on the assets of the Trust or
Trusts to which such expenses are allocable: (1) the expenses and costs of any
action undertaken by the Trustee to protect the Trusts and the rights and
interests of the Unitholders; (2) all taxes and other governmental charges
upon the Securities or any part of the Trusts (no such taxes or charges are
being levied or made or, to the knowledge of the Sponsor, contemplated); (3)
amounts payable to the Trustee as fees for ordinary recurring services and for
extraordinary non-recurring services rendered pursuant to the Indenture, all
disbursements and expenses, including counsel fees (including fees of counsel
which the Trustee may retain) sustained or incurred by the Trustee in
connection therewith; and (4) any losses or liabilities accruing to the
Trustee without negligence, bad faith or willful misconduct on its part. The
expenses are paid monthly and the Trustee is empowered to sell Securities in
order to pay these amounts if funds are not otherwise available in the
applicable Income and Capital Accounts.

  Unless the Sponsor determines that an audit is not required, the Indenture
requires each Trust to be audited on an annual basis at the expense of the
Trust by independent public accountants selected by the Sponsor. The Trustee
shall not be required, however, to cause such an audit to be performed if its
cost to a Trust shall exceed $.05 per Unit on an annual basis. Unitholders of
a Trust covered by an audit may obtain a copy of the audited financial
statements upon request.

Investment Supervision

  The Trusts are unit investment trusts and are not "actively managed" funds.
Traditional methods of investment management for a managed fund typically
involve frequent changes in a portfolio of securities on the basis of
economic, financial and market analyses. The portfolios of the Trusts,
however, will not be actively managed and therefore the adverse financial
condition of an issuer will not necessarily require the sale of its Securities
from the portfolio.

  As a general rule, purchases and sales that will be made with respect to a
Trust's portfolio will be those that seek to maintain, to the extent feasible,
a portfolio which reflects the current components of the stock index, taking
into consideration redemptions, sales of additional Units, cash flows,
expenses and the other factors referred to elsewhere in this Prospectus. See
"THE PORTFOLIOS." Such purchases and sales will generally be made in
accordance with the computer program utilized to maintain the related
portfolio, the Indenture and procedures to be specified by the Sponsor. The
Sponsor or its designated agent may direct the Trustee to dispose of
Securities and either to acquire other Securities through the use of the
proceeds of such disposition in order to make changes in a portfolio, or to
distribute the proceeds of such disposition to Unitholders (i) as necessary to
reflect any additions to or deletions from the stock index, (ii) as may be
necessary to establish a closer correlation between the Trust portfolio and
the stock index, (iii) as may be required for purposes of distributing to
Unitholders, when required, their pro rata share of any net realized capital
gains or income, or (iv) as the Sponsor may otherwise determine. In the event
the Trustee receives any Securities or other properties relating to the
Securities (other than normal dividends) acquired in exchange for Securities
such as those acquired in connection with a reorganization, recapitalization,
merger or other transaction, the Trustee is directed to sell such Securities
or other property. However, if the Securities received are components of the
applicable index, the Sponsor may advise the Trustee to keep such Securities.
Any proceeds received in an exchange shall, as the Sponsor or its designee may
direct, be reinvested into any Securities included in the applicable index, or
distributed to Unitholders. In addition, the Sponsor will instruct the Trustee
to dispose of certain Securities and to take such further action as may be
needed from time to time to ensure that the Trust continues to satisfy the
qualifications of a regulated investment company, including the requirements
with respect to diversification under Section 851 of the Internal Revenue
Code, and as may be needed from time to time to avoid the imposition of any
excise or income tax on the Trust as a regulated investment company. All
purchases and sales are made by the Trustee at the direction of the Sponsor or
its designated agent. The Trustee has no responsibility for the composition of
the Trust portfolio or for loss resulting from any transaction directed by the
Sponsor or its agent. When directed by the Sponsor, the Trustee, or an
affiliate, will enter into foreign exchange transactions with the Trust and
may benefit from such transactions in the ordinary course of its foreign
exchange business.

                                      16
<PAGE>

  Proceeds from the sale of Securities (or any securities or other property
received by a Trust in exchange for Securities) are generally credited to the
Capital Account for distribution to Unitholders, to meet redemptions or for
reinvestment into additional Securities in accordance with the optimization
program. The Trustee may also sell Securities, designated by the Sponsor or
its designated agent, from a Trust for the purpose of redeeming Units of the
Trust tendered for redemption and the payment of expenses. The Sponsor may
consider sales of Units of unit investment trusts which it sponsors in making
recommendations to the Trustee as to the selection of broker/dealers to
execute a Trust's portfolio transactions.

Distributions to Unitholders

  The Trustee will distribute any net income received with respect to any of
the Securities in a Trust on or about the Income Distribution Dates to
Unitholders of record on the preceding Income Record Date. See "Distributions"
in Part A of this Prospectus. Persons who purchase Units will commence
receiving distributions only after such person becomes a Record Owner.
Notification to the Trustee of the transfer of Units is the responsibility of
the purchaser, but in the normal course of business such notice is provided by
the selling broker/dealer. Proceeds received on the sale of any Securities in
a Trust, to the extent not used to meet redemptions of Units, pay the deferred
sales charge or pay expenses will be distributed on the Capital Distribution
Date to Unitholders of record on the Capital Record Date, unless such amounts
are reinvested into additional Securities. The Trustee is not required to pay
interest on funds held in the Capital Account of a Trust (but may itself earn
interest thereon and therefore benefit from the use of such funds). A
Unitholder's pro rata portion of the Capital Account, less expenses, will be
distributed as part of the final liquidation distribution. In addition,
because the Trusts have elected to be taxed as "regulated investment
companies," the Trustee may make such distributions to Unitholders as may be
necessary or desirable to maintain the status of the Trusts as regulated
investment companies or to avoid the imposition of any excise or income tax on
a Trust.

  It is anticipated that the deferred sales charge will be collected from the
Capital Account of the Trusts and that amounts in the Capital Account will be
sufficient to cover the cost of the deferred sales charge. To the extent that
amounts in the Capital Account are insufficient to satisfy the then current
deferred sales charge obligation, Securities may be sold to meet such
shortfall. Distributions of amounts necessary to pay the deferred portion of
the sales charge will be made to an account designated by the Sponsor for
purposes of satisfying a Unitholder's deferred sales charge obligations.

  Under regulations issued by the Internal Revenue Service, the Trustee is
required to withhold a specified percentage of any distribution made by a
Trust if the Trustee has not been furnished the Unitholder's tax
identification number in the manner required by such regulations. Any amount
so withheld is transmitted to the Internal Revenue Service and may be
recovered by the Unitholder under certain circumstances by contacting the
Trustee, otherwise the amount may be recoverable only when filing a tax
return. Under normal circumstances, the Trustee obtains the Unitholder's tax
identification number from the selling broker. However, a Unitholder should
examine his or her statements from the Trustee to make sure that the Trustee
has been provided a certified tax identification number in order to avoid this
possible "back-up withholding." In the event the Trustee has not been
previously provided such number, one should be provided as soon as possible.

  Within a reasonable time after a Trust is terminated, each Unitholder will,
upon surrender of his Units for redemption, receive (i) the pro rata share of
the amounts realized upon the disposition of Securities, and (ii) a pro rata
share of any other assets of such Trust, less expenses of such Trust.

  The Trustee will credit to the Income Account of a Trust any dividends
received on the Securities therein. All other receipts (e.g., return of
capital, etc.) are credited to the Capital Account of a Trust.

  The Trustee may establish reserves (the "Reserve Account") within a Trust
for state and local taxes, if any, and any governmental charges payable out of
such Trust.

  Distribution Reinvestment. Any Unitholder may elect to have each distribu-
tion of income on his Units, other than the final liquidating distribution in
connection with the termination of a Trust, automatically reinvested in addi-
tional Units of such Trust. Each person who purchases Units of a Trust may
elect to participate in the reinvestment option by notifying the Trustee in
writing of their election. Reinvestment may not be available in all states. So
long as the election is received by the Trustee at least 10 days prior to the
Record Date for a given

                                      17
<PAGE>

distribution, each subsequent distribution of income and/or capital, as se-
lected by the Unitholder, will be automatically applied by the Trustee to pur-
chase additional Units of a Trust. The remaining deferred sales charge pay-
ments will be assessed on Units acquired pursuant to reinvestment. It should
be remembered that even if distributions are reinvested, they are still
treated as distributions for income tax purposes.

Accumulation Plan

  The Sponsor is also the principal underwriter of several open-end mutual
funds (the "Accumulation Funds") into which Unitholders may choose to reinvest
Trust distributions. Unitholders may elect to reinvest income and capital
distributions automatically, without any sales charge. Each Accumulation Fund
has investment objectives which differ in certain respects from those of the
Trusts and may invest in Securities which would not be eligible for deposit in
the Trusts. Further information concerning the Accumulation Plan and a list of
Accumulation Funds is set forth in the Information Supplement of this
Prospectus, which may be obtained by contacting the Trustee at (800)-257-8787.

  Participants may at any time, by so notifying the Trustee in writing, elect
to change the Accumulation Fund into which their distributions are being
reinvested, to change from capital only reinvestment to reinvestment of both
capital and income or vice versa, or to terminate their participation in the
Accumulation Plan altogether and receive future distributions on their Units
in cash. Such notice will be effective as of the next Record Date occurring at
least 10 days after the Trustee's receipt of the notice. There will be no
charge or other penalty for such change of election or termination. The
character of Trust distributions for income tax purposes will remain unchanged
even if they are reinvested in an Accumulation Fund.

Reports to Unitholders

  The Trustee shall furnish Unitholders of a Trust in connection with each
distribution, a statement of the amount of income, if any, and the amount of
other receipts (received since the preceding distribution) being distributed,
expressed in each case as a dollar amount representing the pro rata share of
each Unit of a Trust outstanding. Within a reasonable period of time after the
end of each calendar year, the Trustee shall furnish to each person, who at
any time during the calendar year was a registered Unitholder of a Trust, a
statement with respect to such Trust that provides (1) a summary of
transactions in the Trust for such year; (2) any Security sold during the year
and the Securities held at the end of such year by the Trust; (3) the
redemption price per Unit based upon a computation thereof on the 31st day of
December of such year (or the last business day prior thereto); and (4)
amounts of income and capital distributed during such year.

  In order to comply with Federal and state tax reporting requirements,
Unitholders will be furnished, upon request to the Trustee, evaluations of the
Securities in a Trust.

Unit Value and Evaluation

  The value of a Trust is determined by the Trustee on the basis of (1) the
cash on hand in the Trust other than cash deposited in the Trust to purchase
Securities not applied to the purchase of such Securities; (2) the aggregate
value of the Securities held in the Trust, as determined by the Evaluator on
the basis of the aggregate underlying value of the Securities in the Trust
next computed; (3) dividends receivable on the Securities trading ex-dividend
as of the date of computation; and (4) all other assets of the Trust; and
deducting therefrom: (1) amounts representing any applicable taxes or
governmental charges and amounts due the Sponsor or Trustee for
indemnification or extraordinary expenses payable out of such Trust for which
no deductions had been made for the purpose of additions to the Reserve
Account; (2) any amounts owing to the Trustee for its advances; (3) an amount
representing estimated accrued expenses of the Trust, including, but not
limited to, unpaid fees and expenses of the Trustee (including legal fees) and
the Sponsor; (4) amounts representing unpaid organization costs; (5) cash held
for distribution to Unitholders of record of the Trust or for redemption of
tendered Units as of the business day prior to the evaluation being made; and
(6) other liabilities incurred by the Trust. The result of such computation is
divided by the number of Units of such Trust outstanding as of the date
thereof and rounded to the nearest cent to determine the per Unit value ("Unit
Value") of such Trust. The Trustee may determine the aggregate value of the
Securities in a Trust in the following manner: if the Securities are listed on
a foreign or U.S. securities exchange or The NASDAQ Stock Market, Inc.
("listed Securities"), this evaluation

                                      18
<PAGE>

is generally based on the most recent closing sale price prior to the
Evaluation Time on that exchange or that system where the Securities are
principally traded (if a listed Security is listed on the New York Stock
Exchange ("NYSE") the closing sale price on the NYSE shall apply) or, if there
is no closing sale price on that exchange or system, at the closing bid prices
(ask prices for primary market purchases). If the Securities are not so
listed, the evaluation shall generally be based on the current bid prices (ask
prices for primary market purchases) on the over-the-counter market (unless it
is determined that these prices are inappropriate as a basis for valuation).
If current bid prices are unavailable, the evaluation is generally determined
(a) on the basis of current bid prices for comparable securities, (b) by
appraising the value of the Securities on the bid side of the market or (c) by
any combination of the above. For foreign Securities the aggregate underlying
value of the Securities during the initial offering period is computed on the
basis of the offering side value of the relevant currency exchange rate
expressed in U.S. dollars as of the Evaluation Time. After the initial
offering period has ended, the aggregate underlying value of the foreign
Securities is computed on the basis of the bid side value of the relevant
currency exchange rate expressed in U.S. dollars as of the Evaluation Time.

  With respect to any Security not listed on a national or foreign exchange or
The NASDAQ Stock Market, Inc., or, with respect to a Security so listed but in
the unusual circumstance in which the Trustee deems the closing sale price on
the relevant exchange to be inappropriate as a basis for valuation, upon the
Trustee's request, the Sponsor shall, from time to time, designate one or more
evaluation services or other sources of information on which the Trustee shall
be authorized conclusively to rely in evaluating such Security, and the
Trustee shall have no liability for any errors in the information so received.
The cost thereof shall be an expense reimbursable to the Trustee from the
Income and Capital Accounts.

Distributions of Units to the Public

  Nuveen, in addition to being the Sponsor, is the sole Underwriter of the
Units. It is the intention of the Sponsor to qualify Units of the Trusts for
sale under the laws of substantially all of the states of the United States of
America.

  Promptly following the deposit of Securities in exchange for Units of the
Trusts, it is the practice of the Sponsor to place all of the Units as
collateral for a letter or letters of credit from one or more commercial banks
under an agreement to release such Units from time to time as needed for
distribution. Under such an arrangement the Sponsor pays such banks
compensation based on the then current interest rate. This is a normal
warehousing arrangement during the period of distribution of the Units to
public investors. To facilitate the handling of transactions, sales of Units
shall be limited to transactions involving a minimum of either $1,000 or 100
Units ($500 or nearest whole number of Units whose value is less than $500 for
IRA purchases), whichever is less. The Sponsor reserves the right to reject,
in whole or in part, any order for the purchase of Units.

  The Sponsor plans to allow a discount to brokers and dealers in connection
with the distribution of Units. The amounts of such discounts are set forth in
Part A of this Prospectus.

  The Sponsor may maintain a secondary market for Units of each Trust. See
"MARKET FOR UNITS."

  The Sponsor reserves the right to change the amount of the dealer
concessions set forth in Part A of this Prospectus from time to time.

  Volume incentives can be earned as a marketing allowance by Eligible Dealer
Firms who reach cumulative firm sales or sales arrangement levels of a
specified dollar amount of Nuveen unit trusts (other than any series of the
Nuveen--The Dow 5SM Portfolios and Nuveen--The Dow 10SM Portfolios) sold in
the primary or secondary market during any quarter as set forth in the table
below. Eligible Dealer Firms are dealers that are providing marketing support
for Nuveen unit trusts in the form of 1) distributing or permitting the
distribution of marketing materials and other product information, 2)
providing Nuveen representatives access to the dealer's branch offices, and 3)
generally facilitating the placement of orders by the dealer's registered
representatives such as putting Nuveen unit trusts on their order entry
screens. Eligible Dealer Firms will not include firms that solely provide
clearing services to broker/dealer firms. For purposes of determining the
applicable volume incentive rate for a given quarter, the dollar amount of all
units sold over the current and three previous quarters (the "Measuring
Period") is aggregated. The volume incentive received by the dealer firm will
equal the dollar

                                      19
<PAGE>

amount of units sold during the current quarter times the highest applicable
rate for the Measuring Period. For firms that meet the necessary volume level,
volume incentives may be given on all applicable trades originated from or by
that firm.

<TABLE>
<CAPTION>
    Total dollar amount sold
     over Measuring Period                            Volume Incentive
   --------------------------                 --------------------------------
   <S>                                        <C>
   $ 5,000,000 to $ 9,999,999                 0.10% of current quarter sales
   $10,000,000 to $19,999,999                 0.125% of current quarter sales
   $20,000,000 to $49,999,999                 0.1375% of current quarter sales
   $50,000,000 or more                        0.15% of current quarter sales
</TABLE>

  Only sales through the Sponsor qualify for volume incentives and for meeting
minimum requirements. The Sponsor reserves the right to modify or change the
volume incentive schedule at any time and make the determination as to which
firms qualify for the marketing allowance and the amount paid.

  Firms are not entitled to receive any dealer concession or volume incentives
for any sales made to investors which qualified as Discounted Purchases (as
defined in "PUBLIC OFFERING PRICE") during the primary or secondary market.
(See "PUBLIC OFFERING PRICE.")

  Certain commercial banks are making Units of the Trusts available to their
customers on an agency basis. A portion of the sales charge paid by these
customers is retained by or remitted to the banks in the amounts shown in Part
A of the Prospectus under "Dealer Concessions." The Glass-Steagall Act
prohibits banks from underwriting Trust Units; the Act does, however, permit
certain agency transactions and banking regulators have not indicated that
these particular agency transactions are not permitted under the Act. In Texas
and in certain other states, any bank making Units available must be
registered as a broker-dealer under state law.

Ownership and Transfer of Units

  The ownership of Units is evidenced by registered Certificates unless the
Unitholder expressly requests that ownership be evidenced by a book entry
position recorded on the books and records of the Trustee. The Trustee is
authorized to treat as the owner of Units that person who at the time is
registered as such on the books of the Trustee. Any Unitholder who holds a
Certificate may change to book entry ownership by submitting to the Trustee
the Certificate along with a written request that the Units represented by
such Certificate be held in book entry form. Likewise, a Unitholder who holds
Units in book entry form may obtain a Certificate for such Units by written
request to the Trustee. Units may be held in denominations of one Unit or any
multiple or fraction thereof. Fractions of Units are computed to three decimal
places. Any Certificates issued will be numbered serially for identification,
and are issued in fully registered form, transferable only on the books of the
Trustee. Book entry Unitholders will receive a Book Entry Position
Confirmation reflecting their ownership.

  Units are transferable by making a written request to the Trustee and, in
the case of Units evidenced by Certificate(s), by presenting and surrendering
such Certificate(s) to the Trustee, The Chase Manhattan Bank, at 4 New York
Plaza, New York, NY 10004-2413, properly endorsed or accompanied by a written
instrument or instruments of transfer. The Certificate(s) should be sent
registered or certified mail for the protection of the Unitholders. Each
Unitholder must sign such written request, and such Certificate(s) or transfer
instrument, exactly as his name appears on (a) the face of the Certificate(s)
representing the Units to be transferred, or (b) the Book Entry Position
Confirmation(s) relating to the Units to be transferred. Such signature(s)
must be guaranteed by a guarantor acceptable to the Trustee. In certain
instances the Trustee may require additional documents such as, but not
limited to, trust instruments, certificates of death, appointments as executor
or administrator or certificates of corporate authority. Mutilated
Certificates must be surrendered to the Trustee in order for a replacement
Certificate to be issued. Although at the date hereof no charge is made and
none is contemplated, a Unitholder may be required to pay $2.00 to the Trustee
for each Certificate reissued or transfer of Units requested and to pay any
governmental charge which may be imposed in connection therewith.

Replacement of Lost, Stolen or Destroyed Certificates

  To obtain a new Certificate replacing one that has been lost, stolen, or
destroyed, the Unitholder must furnish the Trustee with sufficient
indemnification and pay such expenses as the Trustee may incur. This

                                      20
<PAGE>

indemnification must be in the form of an Open Penalty Bond of
Indemnification. The premium for such an indemnity bond may vary, but
currently amounts to 1% of the market value of the Units represented by the
Certificate. In the case however, of a Trust as to which notice of termination
has been given, the premium currently amounts to 0.5% of the market value of
the Units represented by such Certificate.

Redemption

  Unitholders may redeem all or a portion of their Units by (1) making a
written request for such redemption (book entry Unitholders may use the
redemption form on the reverse side of their Book Entry Position Confirmation)
to the Trustee at 4 New York Plaza, New York, NY 10004-2413 (redemptions of
1,000 Units or more will require a signature guarantee), (2) in the case of
Units evidenced by a Certificate, by also tendering such Certificate to the
Trustee, duly endorsed or accompanied by proper instruments of transfer with
signatures guaranteed as explained above, or provide satisfactory indemnity
required in connection with lost, stolen or destroyed Certificates and (3)
payment of applicable governmental charges, if any. Certificates should be
sent only by registered or certified mail to minimize the possibility of their
being lost or stolen. (See "OWNERSHIP AND TRANSFER OF UNITS.") No redemption
fee will be charged. A Unitholder may authorize the Trustee to honor telephone
instructions for the redemption of Units held in book entry form. Units
represented by Certificates may not be redeemed by telephone. The proceeds of
Units redeemed by telephone will be sent by check either to the Unitholder at
the address specified on his account or to a financial institution specified
by the Unitholder for credit to the account of the Unitholder. A Unitholder
wishing to use this method of redemption must complete a Telephone Redemption
Authorization Form and furnish the Form to the Trustee. Telephone Redemption
Authorization Forms can be obtained from a Unitholder's registered
representative or by calling the Trustee. Once the completed Form is on file,
the Trustee will honor telephone redemption requests by any authorized person.
The time a telephone redemption request is received determines the "date of
tender" as discussed below. The redemption proceeds will be mailed within
three business days following the telephone redemption request. Only Units
held in the name of individuals may be redeemed by telephone; accounts
registered in broker name, or accounts of corporations or fiduciaries
(including among others, trustees, guardians, executors and administrators)
may not use the telephone redemption privilege.

  On the third business day following the date of tender, the Unitholder will
be entitled to receive in cash for each Unit tendered an amount equal to the
Unit Value of such Trust determined by the Trustee, as of 4:00 p.m. eastern
time, or as of any earlier closing time on a day on which the Exchange is
scheduled in advance to close at such earlier time, on the date of tender as
defined hereafter ("Redemption Price"). During the period ending with the
earlier of six months after the Initial Date of Deposit or the end of initial
offering period, the Redemption Price per Unit includes estimated organization
costs per Unit. After such period, the Redemption Price will not include such
estimated organization costs. See "Risk/Return Summary--Fees and Expenses" in
Part A of the Prospectus. The price received upon redemption may be more or
less than the amount paid by the Unitholder depending on the value of the
Securities on the date of tender. Units subject to a deferred sales charge
which are tendered for redemption prior to such time as the entire deferred
sales charge on such Units has been collected will be assessed the amount of
the remaining deferred sales charge at the time of redemption. In addition, in
the event of the death of a Unitholder within the one-year period prior to
redemption, any deferred sales charge remaining at the time of redemption
shall be waived. Unitholders should check with the Trustee or their broker to
determine the Redemption Price before tendering Units.

  The "date of tender" is deemed to be the date on which the request for
redemption of Units is received in proper form by the Trustee, except that a
redemption request received after 4:00 p.m. eastern time, or as of any earlier
closing time on a day on which the Exchange is scheduled in advance to close
at such earlier time, or on any day on which the Exchange is normally closed,
the date of tender is the next day on which such Exchange is normally open for
trading and such request will be deemed to have been made on such day and the
redemption will be effected at the Redemption Price computed on that day.

  Under regulations issued by the Internal Revenue Service, the Trustee may be
required to withhold a specified percentage of the principal amount of a Unit
redemption if the Trustee has not been furnished the redeeming Unitholder's
tax identification number in the manner required by such regulations. For
further information regarding this withholding, see "DISTRIBUTIONS TO
UNITHOLDERS." In the event the Trustee has not been previously provided such
number, one must be provided at the time redemption is requested.

                                      21
<PAGE>

  Any amounts paid on redemption representing income shall be withdrawn from
the Income Account of a Trust to the extent that funds are available for such
purpose, or from the Capital Account. All other amounts paid on redemption
shall be withdrawn from the Capital Account.

  The Trustee is empowered to sell Securities of a Trust in order to make
funds available for redemption. To the extent that Securities are sold, the
size and diversity of the Trust will be reduced. Such sales may be required at
a time when Securities would not otherwise be sold and might result in lower
prices than might otherwise be realized. If Securities of a Trust are sold to
pay redemptions and there are excess proceeds after meeting redemption
requests, the Sponsor, or its designee, may, but is not obligated to, instruct
the Trustee to reinvest such excess proceeds in any Securities included in the
related stock index.

  The Redemption Price per Unit during the secondary market will be determined
on the basis of the Unit Value of a Trust. After the period ending with the
earlier of six months after the Initial Date of Deposit or the end of the
initial offering period, the Redemption Price will not include estimated
organization costs. See "Risk/Return Summary--Fees and Expenses" in Part A of
the Prospectus. See "UNIT VALUE AND EVALUATION" for a more detailed discussion
of the factors included in determining Unit Value. The Redemption Price per
Unit will be assessed the amount, if any, of the remaining deferred sales
charge at the time of redemption.

  The right of redemption may be suspended and payment postponed for any
period during which the New York Stock Exchange is closed, other than for
customary weekend and holiday closings, or during which the Securities and
Exchange Commission determines that trading on the New York Stock Exchange is
restricted or any emergency exists, as a result of which disposal or
evaluation of the Securities is not reasonably practicable, or for such other
periods as the Securities and Exchange Commission may by order permit. Under
certain extreme circumstances, the Sponsor may apply to the Securities and
Exchange Commission for an order permitting a full or partial suspension of
the right of Unitholders to redeem their Units. The Trustee is not liable to
any person in any way for any loss or damage which may result from any such
suspension or postponement.

Purchase of Units by the Sponsor

  The Trustee will notify the Sponsor of any tender of Units for redemption.
If the Sponsor's bid in the secondary market at that time equals or exceeds
the Redemption Price it may purchase such Units by notifying the Trustee
before the close of business on the second succeeding business day and by
making payment therefor to the Unitholder not later than the day on which
payment would otherwise have been made by the Trustee. (See "REDEMPTION.") The
Sponsor's current practice is to bid at the Redemption Price in the secondary
market. Units held by the Sponsor may be tendered to the Trustee for
redemption as any other Units.

Information about the Trustee

  The Trustee is The Chase Manhattan Bank. Its address is 4 New York Plaza,
New York, NY 10004-2413. The Trustee is subject to supervision and examination
by the Federal Deposit Insurance Corporation, the Board of Governors of the
Federal Reserve System and either the Comptroller of the Currency or state
banking authorities.

Limitations on Liabilities of Sponsor and Trustee

  The Sponsor and the Trustee shall be under no liability to Unitholders for
taking any action or for refraining from any action in good faith pursuant to
the Indenture, or for errors in judgment, but shall be liable only for their
own negligence, lack of good faith or willful misconduct. The Trustee shall
not be liable for depreciation or loss incurred by reason of the sale by the
Trustee of any of the Securities. In the event of the failure of the Sponsor
to act under the Indenture, the Trustee may act thereunder and shall not be
liable for any action taken by it in good faith under the Indenture.

  The Trustee shall not be liable for any taxes or other governmental charges
imposed upon or in respect of the Securities or upon the interest thereon or
upon it as Trustee under the Indenture or upon or in respect of any Trust
which the Trustee may be required to pay under any present or future law of
the United States of America or of any other taxing authority having
jurisdiction. In addition, the Indenture contains other customary provisions
limiting the liability of the Trustee.

                                      22
<PAGE>

Successor Trustees and Sponsors

  The Trustee or any successor trustee may resign by executing an instrument
of resignation in writing and filing same with the Sponsor and mailing a copy
of a notice of resignation to all Unitholders then of record. Upon receiving
such notice, the Sponsor is required to promptly appoint a successor trustee.
If the Trustee becomes incapable of acting or is adjudged a bankrupt or
insolvent, or a receiver or other public officer shall take charge of its
property or affairs, the Sponsor may remove the Trustee and appoint a
successor by written instrument. The resignation or removal of a trustee and
the appointment of a successor trustee shall become effective only when the
successor trustee accepts its appointment as such. Any successor trustee shall
be a corporation authorized to exercise corporate trust powers, having
capital, surplus and undivided profits of not less than $5,000,000. Any
corporation into which a trustee may be merged or with which it may be
consolidated, or any corporation resulting from any merger or consolidation to
which a trustee shall be a party, shall be the successor trustee.

  If upon resignation of a trustee no successor has been appointed and has
accepted the appointment within 30 days after notification, the retiring
trustee may apply to a court of competent jurisdiction for the appointment of
a successor.

  If the Sponsor fails to undertake any of its duties under the Indenture, and
no express provision is made for action by the Trustee in such event, the
Trustee may, in addition to its other powers under the Indenture (1) appoint a
successor sponsor or (2) terminate the Indenture and liquidate the Trusts.

Information about the Sponsor

  Since our founding in 1898, Nuveen has been synonymous with investments that
withstand the test of time. Today, we offer a broad range of investments
designed for mature investors whose portfolio is the principal source of their
ongoing financial security. More than 1.5 million investors have entrusted
Nuveen to help them maintain the lifestyle they currently enjoy.

  A value investing approach--purchasing securities of strong companies and
communities that represent good long-term value--is the cornerstone of
Nuveen's investment philosophy. It is a careful, long-term strategy that
offers the potential for attractive returns with moderated risk. Successful
value investing begins with in-depth research and a discerning eye for
marketplace opportunity. Nuveen's team of investment professionals is backed
by the discipline, resources and expertise of a century of investment
experience, including one of the most recognized research departments in the
industry.

  To meet the unique circumstances and financial planning needs of mature
investors, Nuveen offers a wide array of taxable and tax-free investment
products--including equity and fixed-income mutual funds, unit trusts,
exchange-traded funds, customized asset management services and cash
management products.

  Nuveen is a subsidiary of The John Nuveen Company which, in turn, is
approximately 78% owned by the St. Paul Companies, Inc. ("St. Paul"). St. Paul
is located in St. Paul, Minnesota and is principally engaged in providing
property-liability insurance through subsidiaries. Nuveen is a member of the
National Association of Securities Dealers, Inc. and the Securities Industry
Association and has its principal offices located in Chicago (333 West Wacker
Drive). Nuveen maintains eight regional offices.

  To help advisers and investors better understand and more efficiently use an
investment in the Trusts to reach their investment goals, the Sponsor may
advertise and create specific investment programs and systems. For example,
such activities may include presenting information on how to use an investment
in the Trust, alone or in combination with an investment in other mutual funds
or unit investment trusts sponsored by Nuveen, to accumulate assets for future
education needs or periodic payments such as insurance premiums. The Sponsor
may produce software or additional sales literature to promote the advantages
of using the Trusts to meet these and other specific investor needs.

  In advertising and sales literature, the Sponsor may compare the performance
of a given investment strategy or a Trust with that of, or reflect the
performance of: (1) the Consumer Price Index; (2) equity mutual funds or
mutual fund indices as reported by various independent services which monitor
the performance of mutual funds, or other industry or financial publications
such as Barron's, Changing Times, Forbes and Money Magazine;

                                      23
<PAGE>

and/or (3) the S&P 500 Index or other unmanaged indices and investment
strategies. Advertisements involving these indices, investments or strategies
may reflect performance over different periods of time by means of aggregate,
average, year-by-year, or other types of total return and performance figures.
Any given performance quotation or performance comparison should not be
considered as representative of the performance of the Trusts for any future
period. Such advertising may also reflect the standard deviation of the index,
investment or strategy returns for any period. This calculation of standard
deviation is sometimes referred to as the "Sharpe measure" of return.

Information about the Evaluator

  The Trustee will serve as Evaluator of the Trusts. The Sponsor intends to
replace the Trustee as Evaluator during the life of the Trusts.

  The Evaluator may resign or may be removed by the Sponsor or the Trustee, in
which event the Sponsor and the Trustee are to use their best efforts to
appoint a satisfactory successor. Such resignation or removal shall become
effective upon the acceptance of appointment by the successor Evaluator. If
upon resignation of the Evaluator no successor has accepted appointment within
30 days after notice of resignation, the Evaluator may apply to a court of
competent jurisdiction for the appointment of a successor.

  The Trustee, Sponsor and Unitholders may rely on any evaluation furnished by
the Evaluator and shall have no responsibility for the accuracy thereof.
Determinations by the Evaluator under the Indenture shall be made in good
faith upon the basis of the best information available to it, provided,
however, that the Evaluator shall be under no liability to the Trustee,
Sponsor or Unitholders for errors in judgment. This provision shall not
protect the Evaluator in any case of willful misfeasance, bad faith, gross
negligence or reckless disregard of its obligations and duties.

Other Information

Amendment of Indenture

  The Indenture may be amended by the Trustee and the Sponsor without the
consent of any of the Unitholders (1) to cure any ambiguity or to correct or
supplement any provision thereof which may be defective or inconsistent, (2)
to make such amendments as may be necessary for the Trust to continue to
qualify as a regulated investment company for federal income tax purposes, or
(3) to make such other provisions as shall not adversely affect the
Unitholder. Certain other amendments to the Indenture require the approval of
either the consent of 66 2/3% or 100% of Unitholders. However, the Indenture
cannot be amended to (a) alter the rights to the Unitholders as against each
other, (b) provide the Trustee with the power to engage in business or
investment activities other than as specifically provided in the Indenture or
(c) adversely affect the characterization of the Trust as a regulated
investment company for federal income tax purposes. The Trustee shall advise
the Unitholders of any amendment requiring the consent of Unitholders, or upon
request of the Sponsor, promptly after execution thereof.

Termination of Indenture

  A Trust may be liquidated at any time by an instrument executed by the
Sponsor and consented to by 66 2/3% of the Units of the Trust then
outstanding. A Trust may also be liquidated by the Trustee when the value of
such Trust, as shown by any evaluation, is less than 20% of the total value of
the Securities deposited in the Trust as of the conclusion of the primary
offering period and may be liquidated by the Trustee in the event that Units
not yet sold aggregating more than 60% of the Units originally created are
tendered for redemption by the Sponsor. The Indenture also provides that if at
any time the stock index to which the Trust relates is no longer compiled,
maintained or made available, the Sponsor may (a) direct that the Trust
continue to be operated utilizing the components of the related stock index,
as they existed on the last day on which the stock index's components were
available to the Trust; or (b) direct the Trustee to liquidate the Trust in
such a manner as the Sponsor shall direct. The sale of Securities from the
Trust upon termination may result in realization of a lesser amount than might
otherwise be realized if such sale were not required at such time. For this
reason, among others, the amount realized by a Unitholder upon termination may
be less than the amount of Securities originally represented by the Units held
by such Unitholder. The Indenture will terminate upon the redemption, sale or
other disposition

                                      24
<PAGE>

of the last Security held thereunder, but in no event shall it continue beyond
the Mandatory Termination Date set forth under "General Information--
Termination" in Part A of this Prospectus.

  Commencing on the Mandatory Termination Date, Securities will begin to be
sold in connection with the termination of a Trust. The Sponsor will determine
the manner, timing and execution of the sale of the Securities. Written notice
of the termination of a Trust specifying the time or times at which
Unitholders may surrender their certificates for cancellation shall be given
by the Trustee to each Unitholder at his address appearing on the registration
books of such Trust maintained by the Trustee. Unitholders will receive a cash
distribution from the sale of the remaining Securities within a reasonable
time after the Trust is terminated. Regardless of the distribution involved,
the Trustee will deduct from the funds of a Trust any accrued costs, expenses,
advances or indemnities provided by the Indenture, including estimated
compensation of the Trustee and costs of liquidation and any amounts required
as a reserve to provide for payment of any applicable taxes or other
governmental charges. Trustee will then distribute to each Unitholder his pro
rata share of the balance of the Income and Capital Accounts.

Legal Opinion

  The legality of the Units offered hereby has been passed upon by Chapman and
Cutler, 111 West Monroe Street, Chicago, Illinois 60603. Carter, Ledyard &
Milburn, 2 Wall Street, New York, New York 10005, has acted as counsel for the
Trustee with respect to the Series.

Auditors

  The "Statement of Condition" and "Schedule of Investments" at the Initial
Date of Deposit included in Part A of this Prospectus have been audited by
Arthur Andersen LLP, independent public accountants, as indicated in their
report in Part A of this Prospectus, and are included herein in reliance upon
the authority of said firm as experts in giving said report.

Supplemental Information

  Upon written or telephonic request to the Trustee, investors will receive at
no cost to the investor supplemental information about this Trust, which has
been filed with the Securities and Exchange Commission and is intended to
supplement information contained in Part A and Part B of this Prospectus. This
supplement includes additional general information about the Sponsor and the
Trusts.

                                      25
<PAGE>



                            NUVEEN INDEX PORTFOLIO
                             PROSPECTUS -- PART B

                            February 17, 2000

                              Sponsor       John Nuveen & Co. Incorporated
                                            333 West Wacker Drive
                                            Chicago, IL 60606-1286
                                            Telephone: 312-917-7700


                              Trustee       The Chase Manhattan Bank
                                            4 New York Plaza
                                            New York, NY 10004-2413
                                            Telephone: 800-257-8787


             Legal Counsel to Sponsor       Chapman and Cutler
                                            111 West Monroe Street
                                            Chicago, IL 60603


                          Independent       Arthur Andersen LLP
                   Public Accountants       33 West Monroe Street
                       for the Trusts       Chicago, IL 60603

  This Prospectus does not contain complete information about the Unit Trust
filed with the Securities and Exchange Commission in Washington, DC under the
Securities Act of 1933 and the Investment Company Act of 1940.

  To obtain copies at proscribed rates--
    Write: Public Reference Section of the Commission, 450 Fifth Street NW,
           Washington, DC 20549-6009
    Call:  (800) SEC-0330
    Visit: http://www.sec.gov

  No person is authorized to give any information or representation about the
Trusts not contained in Parts A or B of this Prospectus or the Information
Supplement, and you should not rely on any other information.

  When Units of this Trust are no longer available or for investors who will
reinvest into subsequent series of the Trusts, this Prospectus may be used as
a preliminary Prospectus for a future series. If this is the case, investors
should note the following:

    1. Information in this Prospectus is not complete and may be changed;

    2. We may not sell these securities until the registration statement
  filed with the Securities and Exchange Commission is effective; and

    3. This prospectus is not an offer to sell the securities of a future
  series and is not soliciting an offer to buy such securities in any state
  where the offer or sale is not permitted.

<PAGE>

                   NUVEEN UNIT TRUSTS INFORMATION SUPPLEMENT

                               FEBRUARY 17, 2000

                         NUVEEN UNIT TRUSTS, SERIES 81

     The Information Supplement provides additional information concerning the
structure and operations of a Nuveen Unit Trust not found in the prospectuses
for the Trusts. This Information Supplement is not a prospectus and does not
include all of the information that a prospective investor should consider
before investing in a Trust. This Information Supplement should be read in
conjunction with the prospectus for the Trust in which an investor is
considering investing ("Prospectus"). Copies of the Prospectus can be obtained
by calling or writing the Trustee at The Chase Manhattan Bank, 4 New York Plaza,
New York, NY 10004-2413 (800-257-8787). This Information Supplement has been
created to supplement information contained in the Prospectus.

     This Information Supplement is dated February 17, 2000. Capitalized terms
have been defined in the Prospectus.

<PAGE>

                               TABLE OF CONTENTS

Accumulation Plan

Information About the Sponsor

Risk Factors
<PAGE>

Accumulation Plan

     The Sponsor, John Nuveen & Co. Incorporated, is also the principal
underwriter of the Accumulation Funds listed in the following table. Each of
these funds is an open-end, diversified management investment company into which
Unitholders may choose to reinvest Trust distributions automatically, without
any sales charge. Unitholders may reinvest both interest and capital
distributions or capital distributions only. Each Accumulation Fund has
investment objectives which differ in certain respects from those of the Trusts
and may invest in securities which would not be eligible for deposit in the
Trusts. The investment adviser to each Accumulation Fund is a wholly-owned
subsidiary of the Sponsor. Unitholders should contact their financial adviser or
the Sponsor to determine which of the Accumulation Funds they may reinvest into,
as reinvestment in certain of the Accumulation Funds may be restricted to
residents of a particular state or states. Unitholders may obtain a prospectus
for each Accumulation Fund through their financial adviser or through the
Sponsor at (800) 321-7227. For a more detailed description, Unitholders should
read the prospectus of the Accumulation Fund in which they are interested.

     The following is a complete list of the Accumulation Funds currently
available, as of the Date of Deposit of this Prospectus, to Unitholders under
the Accumulation Plan. The list of available Accumulation Funds is subject to
change without the consent of any of the Unitholders.

Accumulation Funds

Mutual Funds

Nuveen Flagship Municipal Trust

     Nuveen Municipal Bond Fund
     Nuveen Insured Municipal Bond Fund
     Nuveen Flagship All-American Municipal Bond Fund
     Nuveen Flagship Limited Term Municipal Bond Fund
     Nuveen Flagship Intermediate Municipal Bond Fund

Nuveen Flagship Multistate Trust I

     Nuveen Flagship Arizona Municipal Bond Fund
     Nuveen Flagship Colorado Municipal Bond Fund
     Nuveen Flagship Florida Municipal Bond Fund
     Nuveen Flagship Florida Intermediate Municipal Bond Fund
     Nuveen Maryland Municipal Bond Fund
     Nuveen Flagship New Mexico Municipal Bond Fund

                                      -3-
<PAGE>

     Nuveen Flagship Pennsylvania Municipal Bond Fund
     Nuveen Flagship Virginia Municipal Bond Fund

Nuveen Flagship Multistate Trust II

     Nuveen California Municipal Bond Fund
     Nuveen California Insured Municipal Bond Fund
     Nuveen Flagship Connecticut Municipal Bond Fund
     Nuveen Massachusetts Municipal Bond Fund
     Nuveen Massachusetts Insured Municipal Bond Fund
     Nuveen Flagship New Jersey Municipal Bond Fund
     Nuveen Flagship New Jersey Intermediate Municipal Bond Fund
     Nuveen Flagship New York Municipal Bond Fund
     Nuveen New York Insured Municipal Bond Fund

Nuveen Flagship Multistate Trust III

     Nuveen Flagship Alabama Municipal Bond Fund
     Nuveen Flagship Georgia Municipal Bond Fund
     Nuveen Flagship Louisiana Municipal Bond Fund
     Nuveen Flagship North Carolina Municipal Bond Fund
     Nuveen Flagship South Carolina Municipal Bond Fund
     Nuveen Flagship Tennessee Municipal Bond Fund

Nuveen Flagship Multistate Trust IV

     Nuveen Flagship Kansas Municipal Bond Fund
     Nuveen Flagship Kentucky Municipal Bond Fund
     Nuveen Flagship Kentucky Limited Term Municipal Bond Fund
     Nuveen Flagship Michigan Municipal Bond Fund
     Nuveen Flagship Missouri Municipal Bond Fund
     Nuveen Flagship Ohio Municipal Bond Fund
     Nuveen Flagship Wisconsin Municipal Bond Fund

Flagship Utility Income Fund

Nuveen Municipal Money Market Fund, Inc.

Nuveen Taxable Funds, Inc.

Nuveen Investment Trust

     Nuveen Growth and Income Stock Fund
     Nuveen Balanced Stock and Bond Fund
     Nuveen Balanced Municipal and Stock Fund
     Nuveen European Value Fund

Nuveen Investment Trust II

     Nuveen Rittenhouse Growth Fund
     Nuveen Innovation Fund
     Nuveen International Growth Fund

Nuveen Investment Trust III

     Nuveen Income Fund

Money Market Funds

     Nuveen California Tax-Free Money Market Fund
     Nuveen Massachusetts Tax-Free Money Market Fund

                                      -4-
<PAGE>

     Nuveen New York Tax-Free Money Market Fund
     Nuveen Tax-Free Reserves, Inc.
     Nuveen Tax-Exempt Money Market Fund, Inc.

     Each person who purchases Units of a Trust may become a participant in the
Accumulation Plan and elect to have his or her distributions on Units of the
Trust invested directly in shares of one of the Accumulation Funds. Reinvesting
Unitholders may elect any interest distribution plan. Thereafter, each
distribution of interest income or principal on the participant's Units
(principal only in the case of a Unitholder who has chosen to reinvest only
principal distributions) will, on the applicable distribution date, or the next
day on which the New York Stock Exchange is nominally open ("Business Day") if
the distribution date is not a business day, automatically be received by the
transfer agent for each of the Accumulation Funds, on behalf of such participant
and applied on that date to purchase shares (or fractions thereof) of the
Accumulation Fund chosen at net asset value as computed as of 4:00 p.m. eastern
time on each such date. All distributions will be reinvested in the Accumulation
Fund chosen and no part thereof will be retained in a separate account. These
purchases will be made without a sales charge.

     The Transfer Agent of the Accumulation Fund will mail to each participant
in the Accumulation Plan a quarterly statement containing a record of all
transactions involving purchases of Accumulation Fund shares (or fractions
thereof) with Trust dividend distributions or as a result of reinvestment of
Accumulation Fund dividends. Any distribution of capital used to purchase shares
of an Accumulation Fund will be separately confirmed by the Transfer Agent.
Unitholders will also receive distribution statements from the Trustee detailing
the amounts transferred to their Accumulation Fund accounts.

     Participants may at any time, by so notifying the Trustee in writing, elect
to change the Accumulation Fund into which their distributions are being
reinvested, to change from capital only reinvestment to reinvestment of both
capital and dividends or vice versa, or to terminate their participation in the
Accumulation Plan altogether and receive future distributions on their Units in
cash. There will be no charge or other penalty for such change of election or
termination. The character of Trust distributions for income tax purposes will
remain unchanged even if they are reinvested in an Accumulation Fund.

                         INFORMATION ABOUT THE SPONSOR

     Since our founding in 1898, Nuveen has been synonymous with investments
that withstand the test of time. Today, we offer a broad range of investments
designed for mature investors whose portfolio is the principal source of their
ongoing financial security. More than 1.3 million investors have entrusted
Nuveen to help them maintain the lifestyle they currently enjoy.

     A value investing approach--purchasing securities of strong companies and
communities that represent good long-term value--is the cornerstone of Nuveen's
investment philosophy. It is a careful, long-term strategy that offers the
potential for consistent, attractive returns with moderated risk. Successful
value investing begins with in-depth

                                      -5-
<PAGE>

research and a discerning eye for marketplace opportunity. Nuveen's team of
investment professionals is backed by the discipline, resources and expertise of
a century of investment experience, including one of the most recognized
research departments in the industry.

     To meet the unique circumstances and financial planning needs of mature
investors, Nuveen offers a wide array of taxable and tax-free investment
products--including equity and fixed-income mutual funds, unit trusts, exchange-
traded funds, customized asset management services and cash management products.

     The Sponsor is also principal underwriter of the registered open-end
investment companies set forth herein under "Accumulation Plan" as well as for
the Golden Rainbow A James Advised Mutual Fund, and acted as co-managing
underwriter of Nuveen Municipal Value Fund, Inc., Nuveen California Municipal
Value Fund, Inc., Nuveen New York Municipal Value Fund, Inc., Nuveen Municipal
Income Fund, Inc., Nuveen Premium Income Municipal Fund, Inc., Nuveen
Performance Plus Municipal Fund, Inc., Nuveen California Performance Plus
Municipal Fund, Inc., Nuveen New York Performance Plus Municipal Fund, Inc.,
Nuveen Municipal Advantage Fund, Inc., Nuveen Municipal Market Opportunity Fund,
Inc. Nuveen California Municipal Market Opportunity Fund, Inc., Nuveen
Investment Quality Municipal Fund, Inc., Nuveen California Investment Quality
Municipal Fund, Inc., Nuveen New York Investment Quality Municipal Fund, Inc.,
Nuveen Insured Quality Municipal Fund, Inc., Nuveen Florida Investment Quality
Municipal Fund, Nuveen Pennsylvania Investment Quality Municipal Fund, Nuveen
New Jersey Investment Quality Municipal Fund, Inc., and the Nuveen Select
Quality Municipal Fund, Inc., Nuveen California Select Quality Municipal Fund,
Inc., Nuveen New York Select Quality Municipal Fund, Inc., Nuveen Quality Income
Municipal Fund, Inc., Nuveen Insured Municipal Opportunity Fund, Inc., Nuveen
Florida Quality Income Municipal Fund, Nuveen Michigan Quality Income Municipal
Fund, Inc., Nuveen Ohio Quality Income Municipal Fund, Inc., Nuveen Texas
Quality Income Municipal Fund, Nuveen California Quality Income Municipal Fund,
Inc., Nuveen New York Quality Income Municipal Fund, Inc., Nuveen Premier
Municipal Income Fund, Inc., Nuveen Premier Insured Municipal Income Fund, Inc.,
Nuveen Select Tax-Free Income Portfolio, Nuveen Select Tax-Free Income Portfolio
2, Nuveen Insured California Select Tax-Free Income Portfolio, Nuveen Insured
New York Select Tax-Free Income Portfolio, Nuveen Premium Income Municipal Fund
2, Inc., Nuveen Select Tax-Free Income Portfolio 3, Nuveen Select Maturities
Municipal Fund, Nuveen Insured California Premium Income Municipal Fund, Inc.,
Nuveen Arizona Premium Income Municipal Fund, Inc., Nuveen Insured Florida
Premium Income Municipal Fund, Nuveen Michigan Premium Income Municipal Fund,
Inc., Nuveen New Jersey Premium Income Municipal Fund, Inc., Nuveen Insured New
York Premium Income Municipal Fund, Inc., Nuveen Premium Income Municipal Fund
4, Inc., Nuveen Pennsylvania Premium Income Municipal Fund 2, Nuveen Maryland
Premium Income Municipal Fund, Nuveen Virginia Premium Income Municipal Fund,
Nuveen Massachusetts Premium Income Municipal Fund, Nuveen Insured California
Premium Income Municipal Fund 2, Inc., Nuveen Washington Premium Income
Municipal Fund, Nuveen Georgia Premium Income Municipal Fund, Nuveen Missouri
Premium Income Municipal Fund, Nuveen Connecticut Premium Income Municipal Fund,
Nuveen North Carolina Premium Income Municipal Fund, Nuveen California Premium
Income Municipal Fund, Nuveen Dividend Advantage Municipal Fund, Nuveen
California Dividend Advantage Municipal Fund, Nuveen New York Dividend Advantage
Municipal Fund, Nuveen

                                      -6-
<PAGE>

Insured Premium Income Municipal Fund 2, all registered closed-end management
investment companies. These registered open-end and closed-end investment
companies currently have approximately $35 billion in securities under
management. Nuveen is a subsidiary of The John Nuveen Company which, in turn, is
approximately 78% owned by the St. Paul Companies, Inc. ("St. Paul"). St. Paul
is located in St. Paul, Minnesota and is principally engaged in providing
property-liability insurance through subsidiaries. Nuveen is a member of the
National Association of Securities Dealers, Inc. and the Securities Industry
Association and has its principal office located in Chicago (333 West Wacker
Drive). Nuveen maintains 8 regional offices.

     To help advisers and investors better understand and more efficiently use
an investment in the Trust to reach their investment goals, the Trust's sponsor,
John Nuveen & Co. Incorporated, may advertise and create specific investment
programs and systems. For example, such activities may include presenting
information on how to use an investment in the Trust, alone or in combination
with an investment in other mutual funds or unit investment trusts sponsored by
Nuveen, to accumulate assets for future education needs or periodic payments
such as insurance premiums. The Trust's sponsor may produce software or
additional sales literature to promote the advantages of using the Trust to meet
these and other specific investor needs.

     The Sponsor offers a program of advertising support to registered broker-
dealer firms, banks and bank affiliates ("Firms") that sell Trust Units or
shares of Nuveen Open-End Mutual Funds (excluding money-market funds) ("Funds").
Under this program, the Sponsor will pay or reimburse the Firm for up to one
half of specified media costs incurred in the placement of advertisements which
jointly feature the Firm and the Nuveen Funds and Trusts. Reimbursements to the
Firm will be based on the number of the Firm's registered representatives who
have sold Fund Shares and/or Trust Units during the prior calendar year
according to an established schedule. Reimbursements under this program will be
made by the Sponsor and not by the Funds or Trusts.

Risk Factors

     An investment in Units should be made with an understanding of the risks
which an investment in common stocks entails, including the risk that the
financial condition of the issuers of the Securities or the general conditions
of the common stock market may worsen and the value of the Securities and
therefore the value of the Units may decline. Common stocks are especially
susceptible to general stock market movements and to volatile increases and
decreases of value as market confidence in and perceptions of the issuers
change. These perceptions are based on unpredictable factors including
expectations regarding government, economic, monetary and fiscal policies,
inflation and interest rates, economic expansion or contraction, and global or
regional political, economic or banking crises. Shareholders of common stocks
have rights to receive payments from the issuers of those common stocks that are
generally subordinate to those of creditors of, or holders of debt obligations
or preferred stocks of, such issuers. Shareholders of common stocks of the type
held by the Trust(s) have a right to receive dividends only when and if, and in
the amounts, declared by the issuer's board of directors and have a right to
participate in amounts available for distribution by the issuer only after all
other claims on the issuer have been paid or provided for. Common stocks do not
represent an obligation of the issuer and, therefore, do not offer any assurance
of income or provide the same degree of protection of capital as do debt
securities. The issuance of additional debt securities or preferred stock will
create prior claims for payment of principal, interest and dividends which could
adversely affect the ability and inclination of the issuer to declare or pay
dividends on its common stock or the rights of holders of common stock with
respect to assets of the issuer upon liquidation or bankruptcy. The value of
common stocks is subject to market fluctuations for as long as the common stocks
remain outstanding, and thus the value of the Securities in a Trust may be
expected to fluctuate over the life of a Trust to values higher or lower than
those prevailing on the Initial Date of Deposit.

     Holders of common stock incur more risk than holders of preferred stocks
and debt obligations because common stockholders, as owners of the entity, have
generally inferior rights to receive payments from the issuer in comparison with
the rights of creditors of, or holders of debt obligations or preferred stocks
issued by, the issuer. Cumulative preferred stock dividends must be paid before
common stock dividends and any cumulative preferred stock dividend omitted is
added to future dividends payable to the holders of cumulative preferred stock.
Preferred stockholders are also generally entitled to rights on liquidation
which are senior to those of common stockholders.

     Foreign Securities Risks. Certain of the Securities in one or more of the
Trusts may be of foreign issuers, and therefore, an investment in such a Trust
involves some investment risks that are different in some respects from an
investment in a Trust that invests entirely in securities of domestic issuers.
Those investment risks include future political and governmental restrictions
which might adversely affect the payment or receipt of payment of dividends on
the relevant Securities, currency exchange rate fluctuations, exchange control
policies, and the limited liquidity and small market capitalization of such
foreign countries' securities markets. In addition, for foreign issuers that are
not subject to the reporting requirements of the Securities Exchange Act of
1934, there may be less publicly available information than is available from a
domestic issuer. Also, foreign issuers are not necessarily subject to uniform
accounting, auditing and financial reporting standards, practices and
requirements comparable to those applicable to domestic issuers. However, due to
the nature of the issuers of the Securities included in the Trust, the Sponsor
believes that adequate information will be available to allow the Sponsor to
provide portfolio surveillance.

    Certain of the Securities in one or more of the Trusts may be in ADR or GDR
form. ADRs, which evidence American Depositary Receipts and GDRs, which evidence
Global Depositary Receipts, represent common stock deposited with a custodian in
a depositary. American Depositary Shares and Global Depositary Shares
(collectively, the "Depositary Receipts") are issued by a bank or trust company
to evidence ownership of underlying securities issued by a foreign corporation.
These instruments may not necessarily be denominated in the same currency as the
securities into which they may be converted. For purposes of the discussion
herein, the terms ADR and GDR generally include American Depositary Shares and
Global Depositary Shares, respectively.

     Depositary Receipts may be sponsored or unsponsored. In an unsponsored
facility, the depositary initiates and arranges the facility at the request of
market makers and acts as agent for the Depositary Receipts holder, while the
company itself is not involved in the transaction. In a sponsored facility, the
issuing company initiates the facility and agrees to pay certain administrative
and shareholder-related expenses. Sponsored facilities use a single depositary
and entail a contractual relationship between the issuer, the shareholder and
the depositary; unsponsored facilities involve several depositaries with no
contractual relationship to the company. The depositary bank that issues
Depositary Receipts generally charges a fee, based on the price of the
Depositary Receipts, upon issuance and cancellation of the Depositary Receipts.
This fee would be in addition to the brokerage commissions paid upon the
acquisition or surrender of the security. In addition, the depositary bank
incurs expenses in connection with the conversion of dividends or other cash
distributions paid in local currency into U.S. dollars and such expenses are
deducted from the amount of the dividend or distribution paid to holders,
resulting in a lower payout per underlying shares represented by the Depositary
Receipts than would be the case if the underlying share were held directly.
Certain tax considerations, including tax rate differentials and withholding
requirements, arising from applications of the tax laws of one nation to
nationals of another and from certain practices in the Depositary Receipts
market may also exist with respect to certain Depositary Receipts. In varying
degrees, any or all of these factors may affect the value of the Depositary
Receipts compared with the value of the underlying shares in the local market.
In addition, the rights of holders of Depositary Receipts may be different than
those of holders of the underlying shares, and the market for Depositary
Receipts may be less liquid than that for the underlying shares. Depositary
Receipts are registered securities pursuant to the Securities Act of 1933 and
may be subject to the reporting requirements of the Securities Exchange Act of
1934.

     For the Securities that are Depositary Receipts, currency fluctuations will
affect the U.S. dollar equivalent of the local currency price of the underlying
domestic share and, as a result, are likely to affect the value of the
Depositary Receipts and consequently the value of the Securities. The foreign
issuers of securities that are Depositary Receipts may pay dividends in foreign
currencies which must be converted into dollars. Most foreign currencies have
fluctuated widely in value against the United States dollar for many reasons,
including supply and demand of the respective currency, the soundness of the
world economy and the strength of the respective economy as compared to the
economies of the United States and other countries. Therefore, for any
securities of issuers (whether or not they are in Depositary Receipt form) whose
earnings are stated in foreign currencies, or which pay dividends in foreign
currencies or which are traded in foreign currencies, there is a risk that their
United States dollar value will vary with fluctuations in the United States
dollar foreign exchange rates for the relevant currencies.

     On January 1, 1999, Austria, Belgium, Finland, France, Germany, Ireland,
Italy, Luxembourg, the Netherlands, Portugal and Spain (eleven of the fifteen
member countries of the European Union ("EU")) are scheduled to establish fixed
conversion rates between their existing sovereign currencies and the euro. On
such date the euro is expected to become the official currency of these eleven
countries. As of January 1, 1999, the participating countries will no longer
control their own monetary policies by directing independent interest rates for
their currencies. Instead, the authority to direct monetary policy, including
money supply and official interest rates for the euro, will be exercised by the
new European Central Bank. The conversion of the national currencies of the
participating countries to the euro could negatively impact the market rate of
the exchange between such currencies (or the newly created euro) and the U.S.
dollar. In addition, European corporations, and other entities with significant
markets or operations in Europe (whether or not in the participating countries),
face strategic challenges as these entities adapt to a single trans-national
currency. The euro conversion may have a material impact on revenues, expenses
or income from operations; increase competition due to the increased price
transparency of EU markets; effect issuers' currency exchange rate risk and
derivatives exposure; disrupt current contracts; cause issuers to increase
spending on information technology updates required for the conversion; and
result in potential adverse tax consequences. The Sponsor is unable to predict
what impact, if any, the euro conversion will have on any of the issuers of
Securities contained in the Trust.

     Software and Technology Issuers. An investment in Units of the Nuveen
Nasdaq 100 Index Portfolio should be made with an understanding of the problems
and risks inherent in the software and technology sectors in general. The
Portfolio includes a concentration of issuers within the software and technology
industries.

     Software and technology companies generally include companies involved in
the development, design, manufacture and sale of computers, software, computer-
related equipment, computer networks, communications systems, telecommunications
products, electronic products and other related products, systems and services.
The market for these products, especially those specifically related to the
Internet, is characterized by rapidly changing technology, rapid product and
service obsolescence, cyclical market patterns, intense competition, evolving
industry standards and frequent new product introductions. The success of the
issuers of the Securities depends in substantial part on the timely and
successful introduction of new products. An unexpected change in one or more of
the technologies affecting an issuer's products or in the market for products
based on a particular technology could have a material adverse effect on an
issuer's operating results. Furthermore, there can be no assurance that the
issuers of the securities will be able to respond in a timely manner to compete
in the rapidly developing marketplace.

     Based on the trading history of software and technology stocks, factors
such as the announcement of new products, the development of new technologies or
the general condition of the industry have caused and are likely to cause the
market price of high-technology common stocks to fluctuate substantially. In
addition, software and technology company stocks have experienced extreme price
and volume fluctuations that often have been unrelated to the operating
performance of such companies. This market volatility may adversely affect the
market price of the securities and therefore the ability of a Unitholder to
redeem Units at a price equal to or greater than the original price paid for
such Units.

     Some key components of certain products of software and technology issuers
are currently available only from single sources. There can be no assurance that
in the future suppliers will be able to meet the demand for components in a
timely and cost effective manner. Accordingly, an issuer's operating results and
customer relationships could be adversely affected by either an increase in
price for, or an interruption or reduction in supply of, any key components.
Additionally, many technology issuers are characterized by a highly concentrated
customer base consisting of a limited number of large customers who may require
product vendors to comply with rigorous industry standards. Any failure to
comply with such standards may result in a significant loss or reduction of
sales. Because many products and technologies of software and technology
companies are incorporated into other related products, such companies are often
highly dependent on the performance of the personal computer, electronics and
telecommunications industries. There can be no assurance that these customers
will place additional orders, or that an issuer of securities will obtain orders
of similar magnitude as past orders from other customers. Similarly, the success
of certain software and technology companies is tied to a relatively small
concentration of products or technologies. Accordingly, a decline in demand of
such products, technologies or from such customers could have a material adverse
impact on issuers of the securities.

     Many software or technology companies rely on a combination of patents,
copyrights, trademarks and trade secret laws to establish and protect their
proprietary rights in their products and technologies. There can be no assurance
that the steps taken by the issuers of the securities to protect their
proprietary rights will be adequate to prevent misappropriation of their
software or technology or that competitors will not independently develop
software or technologies that are substantially equivalent or superior to such
issuers' software or technology. In addition, due to the increasing public use
of the Internet, it is possible that other laws and regulations may be adopted
to address issues such as privacy, pricing, characteristics, and quality of
Internet products and services. The adoption of any such laws could have a
material adverse impact on the securities in the Portfolio. The above factors
could adversely affect the value of the Trust's Units.

                                      -7-
<PAGE>

                      Contents of Registration Statement

A.  Bonding Arrangements of Depositor:

          The Depositor has obtained the following Stockbrokers Blanket Bonds
    for its officers, directors and employees:

          Insurer/Policy No.                                 Amount

          Reliance Insurance Company
          B 262 6895                                       $26,000,000

B. The amendment to the Registration Statement comprises the following papers
    and documents:
                                The facing sheet

                                 The Prospectus

                                 The signatures


                        Consents of Independent Public
                     Accountants and Counsel as indicated

                        Exhibits as listed on page S-5

C.   Explanatory Note

     The Amendment to the Registration Statement may contain multiple separate
prospectuses. Each prospectus will relate to an individual unit investment trust
and will consist of a Part A, a Part B and an Information Supplement. Each
prospectus will be identical with the exception of the respective Part A which
will contain the financial information specific to such underlying unit
investment trust.

D.   Undertakings


     1.   The Information Supplement to the Trust(s) will not include third
party financial information.

                                      S-1
<PAGE>

                                  Signatures

     The Registrant, Nuveen Unit Trusts, Series 81 hereby identifies Series 75,
Series 66, Series 65, Series 63, Series 61, Series 53, Series 52, Series 51,
Series 50, Series 46, Series 43, Series 39, Series 38, Series 37, Series 36,
Series 35, Series 33, Series 4 and Series 1 of the Nuveen Unit Trusts for
purposes of the representations required by Rule 487 and represents the
following:

     (1) that the portfolio securities deposited in the series as to the
securities of which this Registration Statement is being filed do not differ
materially in type or quality from those deposited in such previous series;

     (2) that, except to the extent necessary to identify the specific portfolio
securities deposited in, and to provide essential financial information for, the
series with respect to the securities of which this Registration Statement is
being filed, this Registration Statement does not contain disclosures that
differ in any material respect from those contained in the registration
statements for such previous series as to which the effective date was
determined by the Commission or the staff; and

     (3) that it has complied with Rule 460 under the Securities Act of 1933.

     Pursuant to the requirements of the Securities Act of 1933, the Registrant,
Nuveen Unit Trusts, Series 81 has duly caused this amendment to the Registration
Statement to be signed on its behalf by the undersigned thereunto duly
authorized in the City of Chicago and State of Illinois on the 17th day of
February, 2000.

                                       NUVEEN UNIT TRUSTS, SERIES 81
                                               (Registrant)

                                       By JOHN NUVEEN & CO. INCORPORATED
                                                  (Depositor)

                                       By /s/ Benjamin T. Fulton
                                          ------------------------------
                                       Managing Director and Vice President



                                       Attest    Nicholas Dalmaso
                                              --------------------------
                                                  Assistant Secretary

                                      S-2

<PAGE>

     Pursuant to the requirements of the Securities Act of 1933, this Amendment
to the Registration Statement has been signed below by the following persons in
the capacities and on the date indicated:


<TABLE>
<CAPTION>

     Signature                       Title*                         Date
     ---------                       ------                         ----
<S>                         <C>                             <C>
Timothy R. Schwertfeger     Chairman, Board of Directors, )
                            Chief Executive Officer       )
                            and Director                  )
                                                          )
                                                          )
                                                          )
                                                          )
John P. Amboian             President and Director        )   Larry W. Martin
                                                          )   ---------------
                                                          )   Larry W. Martin
                                                          )  Attorney-in-Fact**
                                                          )
Margaret E. Wilson          Vice President and            )   February 17, 2000
                            Controller                    )
</TABLE>

- ---------

*  The titles of the persons named herein represent their capacity in and
relationship to John Nuveen & Co. Incorporated, the Depositor.

** The power of attorney for Messrs. Amboian and Schwertfeger were filed on
March 20, 1997 as Exhibit P to Form N-8B-2 (File No. 811-08103) and for Ms.
Wilson as Exhibit 6.2 to Nuveen Unit Trusts, Series 12 (File No. 333-49197)
filed on May 14, 1998.

                                      S-3
<PAGE>

                   Consent of Independent Public Accountants

The consent of Arthur Andersen LLP to the use of its name in the Prospectus
included in the Registration Statement is filed by this amendment as Exhibit 4.4
to the Registration Statement.

                         Consent of Chapman and Cutler

The consent of Chapman and Cutler to the use of its name in the Prospectus
included in the Registration Statement is contained in its opinion filed by
this amendment as Exhibit 3.1 to the Registration Statement.

                      Consent of The Chase Manhattan Bank

The consent of The Chase Manhattan Bank to the use of its name in the Prospectus
included in the Registration Statement is filed by this amendment as Exhibit 4.2
to the Registration Statement.

                     Consent of Carter, Ledyard & Milburn

The consent of Carter, Ledyard & Milburn to the use of its name in the
Prospectus included in the Registration Statement is filed by this amendment as
Exhibit 3.2 to the Registration Statement.

                                      S-4
<PAGE>

                                List of Exhibits

1.1(a)  Copy of Standard Terms and Conditions of Trust for Nuveen Unit Trusts,
        Series 4 and certain subsequent series, effective May 29, 1997 between
        John Nuveen & Co. Incorporated, Depositor and The Chase Manhattan Bank,
        Trustee (incorporated by reference to Amendment No. 1 to Form S-6 [File
        No. 333-25225] filed on May 29, 1997 on behalf of Nuveen Unit Trusts,
        Series 4).

1.1(b)  Trust Indenture and Agreement.

1.2     Copy of Certificate of Incorporation, as amended, of John Nuveen & Co.
        Incorporated, Depositor (incorporated by reference to Form N-8B-2 [File
        No. 811-1547] filed on September 27, 1967 on behalf of Nuveen Tax-Exempt
        Unit Trust, Series 16).

1.3     Copy of amendment of Certificate of Incorporation changing name of
        Depositor to John Nuveen & Co. Incorporated (incorporated by reference
        to Form N-8B-2 [File No. 811-2198] filed on April 11, 1985 on behalf of
        Nuveen Tax-Exempt Unit Trust, Series 37).

2.1     Copy of Certificate of Ownership (included in Exhibit 1.1(a) on pages 2
        to 8, inclusive, and incorporated herein by reference).

3.1     Opinion of counsel as to legality of securities being registered.


3.2     Opinion of counsel as to advancement of funds by Trustee.

4.2     Consent of The Chase Manhattan Bank.

4.4     Consent of Arthur Andersen LLP.

6.1     List of Directors and Officers of Depositor and other related
        information (incorporated by reference to Exhibit E to Form N-8B-2 [File
        No. 811-08103] filed on March 20, 1997 on behalf of Nuveen Unit Trusts,
        Series 1 and subsequent Series).

                                      S-5

<PAGE>

                                                                  Exhibit 1.1(b)

                         Nuveen Unit Trusts, Series 81

                         Trust Indenture and Agreement

                           Dated: February 17, 2000

     This Trust Indenture and Agreement by and between John Nuveen & Co.
Incorporated, as Depositor and The Chase Manhattan Bank, as Trustee, sets forth
certain provisions in full and incorporates other provisions by reference to the
document entitled "Standard Terms and Conditions of Trust for Nuveen Unit Trust,
Series 4 and certain subsequent Series, effective May 29, 1997" (herein called
the "Standard Terms and Conditions of Trust"), and such provisions as are set
forth in full and such provisions as are incorporated by reference constitute a
single instrument. All references herein to Articles and Sections are to
Articles and Sections of the Standard Terms and Conditions of Trust.

                                Witnesseth That:

     In consideration of the promises and of the mutual agreements herein
contained, the Depositor and the Trustee, agree as follows:

                                     Part I

                     Standard Terms and Conditions of Trust

     Subject to the Provisions of Part II hereof, all the provisions contained
in the Standard Terms and Conditions of Trust are herein incorporated by
reference in their entirety and shall be deemed to be a part of this instrument
as fully and to the same extent as though said provisions had been set forth in
full in this instrument.

                                    Part II

                     Special Terms and Conditions of Trust

     The following special terms and conditions are hereby agreed to:

     (a) The Securities defined in Section 1.01(1) listed in Schedule A hereto
have been deposited in trust under this Trust Indenture and Agreement.

     (b) The fractional undivided interest in and ownership of the Trust Fund
represented by each Unit for the Trust(s) on the Initial Date of Deposit is
1/(the number of Units) set forth under the caption "Statement(s) of Condition--
Interest of Unitholders: Units of fractional undivided interest outstanding" in
the Prospectus.
<PAGE>


     (c)  The number of Units created of the Trust(s) are as set forth under the
caption "Statement(s) of Condition--Interest of Unitholders: Units of fractional
undivided interest outstanding" in the Prospectus for the Trust(s).

     (d)  Each Trust elects to be treated and to qualify as a Regulated
          Investment Company as defined in the Internal Revenue Code, and the
          Trustee is hereby directed to make such elections, including any
          appropriate election to be taxed as a corporation, as shall be
          necessary to effect such qualification.

     (e)  Section 10.02 shall be amended to read in its entirety as follows:

               Section 10.02. Initial Costs. Subject to reimbursement as
     hereinafter provided, the cost of organizing the Trust(s) and the sale of
     the Trust Units shall be borne by the Depositor, provided, however, that
     the liability on the part of the Depositor under this section shall not
     include any fees or other expenses incurred in connection with the
     administration of the Trust(s) subsequent to the deposit referred to in
     Section 2.01. At the earlier of six months after the Initial Date of
     Deposit or the conclusion of the primary offering period (as certified by
     the Depositor to the Trustee), the Trustee shall withdraw from the Account
     or Accounts specified in the Prospectus or, if no Account is therein
     specified, from the Capital Account, and pay to the Depositor the
     Depositor's reimbursable expenses of organizing the Trust(s) in an amount
     certified to the Trustee by the Depositor. In no event shall the amount
     paid by the Trustee to the Depositor for the Depositor's reimbursable
     expenses of organizing the Trust(s) exceed the estimated per Unit amount of
     organization costs set forth in the prospectus for the Trust(s) multiplied
     by the number of Units of the Trust(s) outstanding at the earlier of six
     months after the Initial Date of Deposit or the end of the initial offering
     period; nor shall the Depositor be entitled to or request reimbursement for
     expenses of organizing the Trust(s) incurred after the earlier of six
     months after the Initial Date of Deposit or the end of the initial offering
     period. If the cash balance of the Capital Account is insufficient to make
     such withdrawal, the Trustee shall, as directed by the Depositor, sell
     Securities identified by the Depositor, or distribute to the Depositor
     Securities having a value, as determined under Section 4.01 as of the date
     of distribution, sufficient for such reimbursement. Securities sold or
     distributed to the Depositor to reimburse the Depositor pursuant to this
     Section shall be sold or distributed by the Trustee, in accordance with the
     instructions of the Depositor or its designee. The reimbursement provided
     for in this section shall be for the account of the Unitholders of record
     at the earlier of six months after the Initial Date of Deposit or the
     conclusion of the primary offering period. Any assets deposited with the
     Trustee in respect of the expenses reimbursable under this Section 10.02
     shall be held and administered as assets of the Trust(s) for all purposes
     hereunder. The Depositor shall deliver to the Trustee any cash identified
     in the Statement(s) of Condition of the Trust(s) included in the Prospectus
     not later than the 10 calendar days following the Initial Date of Deposit
     or deposit of additional Securities, as applicable and the Depositor's
     obligation to make such delivery shall be secured by the letter of credit
     deposited pursuant to Section 2.01. Any cash which the Depositor has
     identified as to be used for reimbursement of expenses pursuant to this
     Section 10.02 shall be held by the Trustee, without interest, and reserved
     for such purpose and, accordingly, prior to the earlier of six months after
     the Initial Date of Deposit or the conclusion of the primary offering
     period, shall not be subject to distribution or, unless the Depositor
     otherwise directs, used for payment of redemptions in excess of the per
     Unit amount payable pursuant to the next sentence. If a Unitholder redeems
     Units prior to the earlier of six months after the Initial Date of Deposit
     or the conclusion of the primary offering period, the Trustee shall pay to
     the Unitholder, in

                                      -2-
<PAGE>


     addition to the Redemption Value of the tendered Units, unless otherwise
     directed by the Depositor, an amount equal to the estimated per Unit cost
     of organizing the Trust(s) set forth in the Prospectus, or such lower
     revision thereof most recently communicated to the Trustee by the Depositor
     pursuant to Section 5.01, multiplied by the number of Units tendered for
     redemption; to the extent the cash on hand in the Trust(s) is insufficient
     for such payment, the Trustee shall have the power to sell Securities in
     accordance with Section 5.02. As used herein, the Depositor's reimbursable
     expenses of organizing the Trust(s) shall include the cost of the initial
     preparation and typesetting of the registration statement, prospectuses
     (including preliminary prospectuses), the indenture, and other documents
     relating to the Trust(s), SEC and state blue sky registration fees, the
     cost of the initial valuation of the portfolio and audit of the Trust(s),
     the initial fees and expenses of the Trustee, and legal and other out-of-
     pocket expenses related thereto, but not including the expenses incurred in
     the printing of preliminary prospectuses and prospectuses, expenses
     incurred in the preparation and printing of brochures and other advertising
     materials and any other selling expenses.

     (f) Article I of the Standard Terms and Conditions of Trust is hereby
amended to replace the definitions of "Capital Distribution Date," "Contract
Securities," "Initial Date of Deposit," "Mandatory Termination Date," "Record
Date," "Securities" and "Unit" and to add the following definitions:

     Capital Distribution Date

          The meaning assigned to it in the Prospectus for a Trust.

     Contract Securities

          The Securities which are to be acquired by any Trust Fund pursuant to
     a contract or contracts for the purchase of such securities which have been
     assigned to the Trustee along with the amounts required for their purchase
     which have been delivered to the Trustee.

     Evaluator

          The party designated in the Prospectus for a Trust or any party
     appointed by the Sponsor.

     Initial Date of Deposit

          The meaning assigned to it in the Prospectus for each respective Trust
     Fund.

     Mandatory Termination Date

          The meaning assigned to it in the Prospectus for a Trust.

                                      -3-
<PAGE>

     Prospectus

          The prospectus relating to a Trust in the form first used to confirm
     sales of Units.

     Record Date

          As applicable, the meaning assigned in "Income Record Date" and/or
     "Capital Record Date" in the Prospectus for each respective Trust Fund.

     Securities

          The securities, including Contract Securities listed in Schedule A to
     the Trust Agreement or other securities that may be deposited in the Trust
     Fund and any obligations received in exchange or substitution for such
     securities, as may from time to time continue to be held as a part of any
     Trust Fund.

     Unit

          The fractional undivided interest in and ownership of an individual
     Trust Fund equal initially to 1/(the number of Units of fractional
     undivided interest outstanding) provided in the Statement of Condition in
     the Prospectus for the Trust Fund, the denominator of which fraction shall
     be (1) increased by the number of any additional Units issued pursuant to
     Section 2.03 hereof and (2) decreased by the number of any such Units
     redeemed as provided in Section 5.02. Whenever reference is made herein to
     the "interest" of a Unitholder in the Trust Fund or in the Income or
     Capital Accounts, it shall mean such fractional undivided interest
     represented by the number of Units, whether or not evidenced by a
     Certificate or Certificates, held of record by such Unitholder in such
     Trust Fund.

In addition, the definitions of "Rollover Distribution," "Rollover Notification
Date," "Rollover Unitholder" and "Special Redemption and Liquidation Period"
shall be deleted.

      (g) The following subsection (d) shall be added to Section 7.02:

          (d) The Depositor may employ agents in connection with its duties
     under Section 3.11 and 3.13 hereof and shall not be answerable for the
     default or misconduct of such agents if they shall have been selected with
     reasonable care. The fees of such agents shall be reimbursable to the
     Depositor from the Trust Fund, provided, however, that the


                                      -4-
<PAGE>

     amount of such reimbursement in any year (i) shall reduce the amount
     payable to the Depositor for such year with respect to the service in
     question and shall not exceed the maximum amount payable to the Depositor
     for such service for such year and (ii) if such agent is an affiliate of
     the Depositor, the amount of the reimbursement, when combined with (a) all
     compensation received by such agent from other series of the Fund or other
     unit investment trusts sponsored by the Depositor or its affiliates and (b)
     the amount payable to the Depositor from the Trust Fund and from other
     series of the Fund or other unit investment trusts sponsored by the
     Depositor or its affiliates in respect of the service in question, shall
     not exceed the aggregate cost of such agent and the Depositor of providing
     such service. The Trustee shall pay such reimbursement against the
     Depositor's invoice therefor upon which the Trustee may rely as the
     Depositor's certification that the amount claimed complies with the
     provisions of this paragraph.

     (h)  Section 4.01 shall be amended to read in its entirety as follows:

     Section 4.01. Evaluation of Securities. The Evaluator shall determine
     separately and promptly furnish to the Trustee and the Depositor upon
     request the value of each issue of Securities as of the Evaluation Time as
     provided in the following manner:

          (a)  The Evaluator will prepare each evaluation for which market
     quotations for the Securities are available by the use of outside services
     normally used and contracted with for this purpose. If the Securities are
     listed on a national or foreign securities exchange or The NASDAQ Stock
     Market, Inc., the evaluation will be based on the closing sale price on the
     exchange or system where the Securities are principally traded (if a
     Security is listed on the New York Stock Exchange, the closing sale price
     on that exchange shall apply) or, if there is no closing sale price on the
     exchange or system, at the closing bid price on the exchange or system. If
     such market quotations are not available, the Evaluator shall determine the
     value of the Securities. Such evaluation shall generally be based on the
     current bid prices on the over-the-counter market (unless it is determined
     that these prices are inappropriate as a basis for evaluation). If such
     prices are not available on the over-the-counter market, the evaluation
     will generally be made by the Evaluator in good faith (1) on the basis of
     the current bid prices for comparable securities, (2) by the Evaluator's
     appraising the value of the Securities in good faith at the bid side of the
     market or (3) by any combination thereof. If such prices are in a currency
     other than U.S. dollars, the Evaluation of such Security shall be converted
     to U.S. dollars based on current bid side exchange rates, unless the
     Security is in the form of an American Depositary Share or Receipt, in
     which case the Evaluations shall be based upon the U.S. dollar prices in
     the market for American Depositary Shares or Receipts (unless the Evaluator
     deems such prices inappropriate as a basis for valuation). As used herein,
     the closing sale price is deemed to mean the most recent closing sale price
     on the relevant securities exchange immediately prior to the Evaluation
     Time.

     For each evaluation, the Evaluator shall also determine and furnish to the
     Trustee and the Depositor the aggregate of (a) the value of all Securities
     on the basis of such evaluation and (b) on the basis of the information
     furnished to the Evaluator by the Trustee pursuant to Section 3.02, the
     amount of cash then held in the Capital Account which was received by the
     Trustee after the Record Date preceding such determination less any amounts
     held in the Capital Account for distribution to Unitholders on a subsequent
     Distribution Date when a Record Date occurs four business days or less
     after such determination. For the purposes of the foregoing, the Evaluator
     may obtain current prices for the Securities from investment dealers or
     brokers (including the Depositor) that customarily deal in similar
     securities.

     With respect to any Security not listed on a national or foreign exchange
     or The NASDAQ Stock Market, Inc., or, with respect to a Security so listed
     but in the unusual circumstance in which the Evaluator deems the closing
     sale price on the relevant exchange to be inappropriate as a basis for
     valuation, upon the Evaluator's request, the Depositor shall,

                                      -5-
<PAGE>


     from time to time, designate one or more evaluation services or other
     sources of information on which the Evaluator shall be authorized
     conclusively to rely in evaluating such Security. The Depositor shall also
     designate one or more banks (which may include the Trustee) or other source
     of information from which the Evaluator shall take foreign exchange rate
     quotations. The Evaluator shall have no liability for any errors in the
     information received from any source designated by the Depositor. The cost
     thereof shall be an expense reimbursable to the Evaluator from the Income
     and Capital Accounts.

          (b)  Notwithstanding Section 4.01(a), except in those cases in which
     the Securities are listed on a national or foreign securities exchange or
     The NASDAQ Stock Market, Inc., and the closing sales prices are used and
     except for Trust Fund Evaluations required by Section 5.02 in determining
     Redemption Price, during the initial offering period, the evaluations of
     the Securities shall generally be made in the manner described in Section
     4.01(a) based on the closing ask prices of the Securities rather than the
     closing bid prices and on current offering side exchange rates.

     (i)  Section 5.01 shall be amended to read in its entirety as follows:

     Section 5.01. Trust Fund Evaluation. As of the Evaluation Time next
     following any tender by a Unitholder for redemption and on any other
     business day desired by it or as may be required hereunder, the Trustee
     shall as to each Trust Fund:

     Add--

          (1)  cash on hand in the Trust Fund (other than cash held especially
     for the purchase of Contract Securities) and moneys in the process of being
     collected from declared dividends,

          (2)  the aggregate value of each issue of the Securities in the Trust
     Fund (including Contract Securities) as determined by the Evaluator
     pursuant to Section 4.01, and

          (3)  all other assets of a Trust;

     Deduct--

          (1)  amounts representing any applicable taxes, governmental charges
     or other charges pursuant to Section 3.03 payable out of the Trust Fund and
     for which no deductions shall have previously been made for the purpose of
     addition to the Reserve Account,

          (2)  amounts representing estimated accrued fees and expenses of the
     Trust Fund including but not limited to unpaid fees and expenses of the
     Trustee (including legal and auditing expenses), the Evaluator, the
     Depositor and counsel, and

          (3)  amounts representing unpaid accrued organization costs, and

                                      -6-
<PAGE>

          (4) cash allocated for distribution to Unitholders of the Trust Fund
     of record as of the business day prior to the evaluation then being made.

     The resulting figure is herein called a "Trust Fund Evaluation."

     Prior to the payment to the Depositor of its reimbursable organization
     costs to be made at the earlier of six months after the Initial Date of
     Deposit or the conclusion of the primary offering period in accordance with
     Section 10.02, for purposes of determining the Trust Fund Evaluation under
     this Section 5.01, the Trustee shall rely upon the amounts representing
     unpaid accrued organization costs in the estimated amount per Unit set
     forth in the Prospectus until such time as the Depositor notifies the
     Trustee in writing of a revised estimated amount per Unit representing
     unpaid accrued organization costs. Upon receipt of such notice, the Trustee
     shall use this revised estimated amount per Unit representing unpaid
     accrued organization costs in determining the Trust Fund Evaluation but
     such revision of the estimated expenses shall not effect calculations made
     prior thereto and no adjustment shall be made in respect thereof.

     Amounts receivable by the Trust(s) in a foreign currency shall be reported
     to the Evaluator who shall convert the same to U.S. dollars based on
     current exchange rates, in the same manner as provided in Section 4.01, for
     the conversion of the valuation of foreign Securities, and the Evaluator
     shall report such conversion with each Evaluation made pursuant to Section
     4.01.

     (j) Notwithstanding anything to the contrary contained in Sections 3.04,
3.11, 3.13, 4.03 and 8.05 or otherwise herein, expenses of each Trust shall be
paid to the appropriate party on or about the 15th day of each month. Until the
Trustee is notified by the Depositor that the primary offering period has
terminated, the fees, where applicable, shall be accrued daily and based on the
number of Units outstanding on each day.

After the primary offering period has terminated, the fees, where applicable,
shall be based on the number of Units outstanding on the most recent prior
Income Record Date specified in the Prospectus or the number of Units
outstanding at the end of the initial offering period, as appropriate.

     (k) Paragraph (e) of Section 8.01 of Article VIII of the Standard Terms and
Conditions of Trust is amended to read as follows:

           (e) (I) Subject to the provisions of subparagraphs (II) and (III) of
this paragraph, the Trustee may employ agents, sub-custodians, attorneys,
accountants and auditors and shall not be answerable for the default or
misconduct of any such agents, sub-custodians, attorneys, accountants or
auditors if such agents, sub-custodians, attorneys, accountants or auditors
shall have been selected with reasonable care. The Trustee shall be fully
protected in respect of any action under this Indenture taken or suffered in
good faith by the Trustee in accordance with the opinion of counsel, which may
be counsel to the Depositor acceptable to the Trustee, provided, however, that
this disclaimer of liability shall not (i) excuse the Trustee from the
responsibilities specified in subparagraph II below or (ii) limit the obligation
of the Trustee to indemnify the Trust(s) under subparagraph III below. The fees
and expenses charged by such agents, sub-custodians, attorneys, accountants or
auditors shall constitute an expense of the Trust(s) reimbursable from the
Income and Capital Accounts of the affected Trust as set forth in section 8.05
and 3.04 hereof.

          (II) The Trustee may place and maintain in the care of an eligible
     foreign custodian (which is employed by the Trustee as a sub-custodian as
     contemplated by subparagraph (I) of this paragraph (e) and which may be an
     affiliate or subsidiary of the Trustee or any other entity in which the
     Trustee may have an ownership interest) a Trust's foreign securities, cash
     and cash equivalents in amounts reasonably necessary to effect the Trust's
     foreign securities transactions, provided that the Trustee hereby agrees to
     perform all the duties assigned by rule 17f-5 as now in effect or as it may
     be amended in the future, to the boards of management investment companies.
     The Trustee's duties under the preceding sentence will not be
     delegated.

          As used in this subparagraph (II),

               (1)  "foreign securities" include: securities issued and sold
     primarily outside the United States by a foreign government, a national of
     any foreign country or a corporation or other organization incorporated or
     organized under the laws of any foreign country and securities issued or
     guaranteed by the government of the United States or by any state or any
     political subdivision thereof or by any agency thereof or by any entity
     organized under the laws of the United States or of any state thereof which
     have been issued and sold primarily outside the United States.

               (2)  "eligible foreign custodian" means

               (a)  The following securities depositories and clearing agencies
     which operate transnational systems for the central handling of securities
     or equivalent book entries which, by appropriate exemptive order issued by
     the Securities and Exchange Commission, have been qualified as eligible
     foreign custodians for the Trust(s) but only for so long as such exemptive
     order continues in effect: the Euroclear System ("Euroclear"), and Cedel
     Bank S.A. ("CEDEL").

               (b)  Any other entity that shall have been qualified as an
     eligible foreign custodian for the foreign securities of the Trust(s) by
     the Securities and Exchange Commission by exemptive order, rule or other
     appropriate action, commencing on such date as it shall have been so
     qualified but only for so long as such exemptive order, rule or other
     appropriate action continues in effect.

               (III)  The Trustee will indemnify and hold the Trust(s) harmless
     from and against any loss occurring as a result of an eligible foreign
     custodian's willful misfeasance, reckless disregard, bad faith, or gross
     negligence in performing custodial duties.

     (l) Section 8.01(i) shall be amended to read in its entirety as follows:

          (i) Notwithstanding any provisions of this Agreement to the contrary,
     no payment to a Depositor or to any principal underwriter (as defined in
     the Investment Company Act of 1940) for each Trust Fund or to any
     affiliated person (as so defined) or agent of a Depositor or such
     underwriter shall be allowed the Trustee as an expense except for payment
     of such reasonable amounts as the Securities and Exchange Commission may
     prescribe as compensation for performing bookkeeping and other
     administrative services of a character normally performed by the
     Trustee.

     (m) Section 8.01 shall be amended to add the following paragraph (m):

     (m) The Chase Manhattan Bank, or an affiliate, may, when instructed by the
Sponsor pursuant to Section 3.14, enter into foreign exchange transactions with
the Trust(s), with the same rights and powers as if The Chase Manhattan Bank
were not the Trustee hereunder.


                                      -7-
<PAGE>


     (n)  All references to the "NASDAQ National Market System" herein and in
the Standard Terms and Conditions of Trust shall be replaced with "The NASDAQ
Stock Market, Inc."

     (o)  Subsection (b) of Section 2.01 shall be restated in its entirety as
follows:

          (b)  (1) From time to time following the Initial Date of Deposit for a
     Trust, the Depositor is hereby authorized, in its discretion, to assign,
     convey to and deposit with the Trustee (i) additional Securities for such
     Trust, duly endorsed in blank or accompanied by all necessary instruments
     of assignment and transfer in proper form, or (ii) Contract Securities
     relating to such additional Securities, accompanied by cash and/or
     Letter(s) of Credit as specified in paragraph (c) of this Section 2.01. In
     lieu of additional Securities or Contract Securities, the Depositor may
     deposit with the Trustee cash (or a Letter of Credit) in an amount equal to
     the valuation made in accordance with Section 4.01 for the date of such
     deposit of the additional Securities not delivered or represented by
     Contract Securities and the Depositor or its designated agent shall, on
     behalf of each Trust, enter into contracts to purchase such additional
     Securities and shall provide the Trustee such information as the Trustee
     may require in order to settle such transactions and take delivery of such
     additional Securities which the Trustee is hereby directed to do. Deposits
     of additional Securities shall consist of Securities included in the Nasdaq
     100 Index for the Nuveen Nasdaq 100 Index Portfolio and the Dow Jones
     Global Titans Index for the Nuveen Dow Jones Global Titans Index Portfolio
     as determined by the Depositor or its designee. Any brokerage fees related
     to the purchase of Securities deposited in the Trust Fund after the Initial
     Date of Deposit shall be an expense of such Trust Fund. The Depositor shall
     deliver any additional Securities which were not delivered concurrently
     with the deposit of additional Securities and which were represented by
     Contract Obligations within 10 calendar days after such deposit of
     additional Securities (the "Additional Securities Delivery Period"). If a
     contract to buy such Securities between the Depositor and seller is
     terminated by the seller thereof for any reason beyond the control of the
     Depositor or if for any other reason such Securities are not delivered to a
     Trust by the end of the Additional Securities Delivery Period for such
     deposit, the Trustee shall immediately draw on the Letter of Credit, if
     any, in amounts sufficient to settle such contract, apply the monies in
     accordance with Section 2.01(d), and the Depositor shall forthwith take the
     remedial action specified in Section 3.10. If the Depositor does not take
     the action specified in Section 3.10 within 10 calendar days of the end of
     the Additional Securities Delivery Period, the Trustee shall forthwith take
     the action specified in Section 3.10. If the Depositor has acted as broker
     in connection with any purchase of Securities made on behalf of a Trust,
     which it is hereby authorized to do, it shall be entitled to reimbursement
     in accordance with applicable law and regulations. The Trustee shall have
     no liability for any loss or depreciation resulting from any acquisition of
     Securities pursuant to this Section (other than to confirm the identity and
     amount of Securities delivered to it pursuant to contracts deposited or
     entered into by the Depositor) and shall have no responsibility for the
     composition of a Trust portfolio.

          (2) Additional Securities (or Contract Securities therefor) may, at
     the Depositor's discretion, be deposited or purchased in round lots. If the
     amount of the deposit is insufficient to acquire round lots of each
     Security to be acquired, the additional Securities shall be deposited or
     purchased in accordance with the instructions of the Depositor or its
     designee.

                                      -8-
<PAGE>


          (3) If at the time of a deposit of additional Securities, Securities
     of an issue deposited on the Initial Date of Deposit (or of an issue of
     Replacement Securities acquired to replace an issue deposited on the
     Initial Date of Deposit) are unavailable, cannot be purchased at reasonable
     prices or their purchase is prohibited or restricted by applicable law,
     regulation or policies, the Depositor may (i) deposit, or purchase on
     behalf of each Trust or designate an agent to purchase on behalf of each
     Trust in respect of cash deposited therein for such purpose, in lieu
     thereof, another issue of Securities or Replacement Securities or (ii)
     deposit cash or a letter of credit in an amount equal to the valuation of
     the issue of Securities whose acquisition is not feasible and enter into
     contracts, or designate an agent to enter into contracts, on behalf of a
     Trust to acquire such Securities of such issue when they become available.

          (4) In connection with and at the time of any deposit of additional
     Securities pursuant to this Section 2.01 (b), the Depositor shall exactly
     replicate Cash (as defined below) received or receivable by the Trust(s) as
     of the date of such deposit. For purposes of this paragraph, "Cash" means,
     as to the Capital Account, cash or other property (other than Securities)
     on hand in the Capital Account or receivable and to be credited to the
     Capital Account as of the date of the deposit (other than amounts to be
     distributed solely to persons other than holders of Units created by the
     deposit) and, as to the Income Account, cash or other property (other than
     Securities) received by the Trust(s) in respect of a record date for a
     payment on a Security which has occurred or will occur before the Trusts
     will be the holder of record of a Security, reduced by (i) the amount of
     any cash or other property received or receivable on any Security allocable
     (in accordance with the Trustee's calculations of distributions from the
     Income Account pursuant to Section 3.05) to a distribution made or to be
     made in respect of a Record Date occurring prior to the deposit and (ii)
     unpaid fees and expenses allocable to the period prior to the deposit. Such
     replication will be made on the basis of a fraction, the numerator of which
     is the number of Units created by the deposit and the denominator of which
     is the number of Units which are outstanding immediately prior to the
     deposit. Cash represented by a foreign currency shall be replicated in such
     currency or, if the Trustee has entered into a contract for the conversion
     thereof, in U.S. dollars in an amount replicating the dollars to be
     received on such conversion.

     (p) Section 2.01(c) of the Standard Terms and Conditions of Trust is hereby
     amended by adding the following at the conclusion thereof:

     "If any Contract Obligation requires settlement in a foreign currency, in
     connection with the deposit of such Contract Obligation the Depositor will
     deposit with the Trustee either an amount of such currency sufficient to
     settle the contract or a foreign exchange contract in such amount which
     settles concurrently with the settlement of the Contract Obligation and
     cash or a Letter of Credit in U.S. dollars sufficient to perform such
     foreign exchange contract."

     (q) The second paragraph of Section 3.04(b) shall have the following added
     to the end of the paragraph:

     Notwithstanding anything to the contrary contained in this paragraph, the
     Depositor or its designee may, but is not obligated to, direct the
     investment of any amounts held in the Capital Account that have not
     previously been used to pay for the redemption of Units tendered to a Trust
     Fund, into any Securities included in the applicable index.

     (r) The following shall be added as subsection (f) to Section 3.04:

          (f) Notwithstanding the foregoing, if a Trust has elected to be taxed
     as a "regulated investment company" as defined in the United States
     Internal Revenue Code of 1986, as amended, the Trustee shall make such
     additional distributions to Unitholders as shall be determined by the
     Depositor or such agent as the Depositor shall designate to be necessary or
     desirable to maintain the status of each Trust as a Regulated Investment
     Company or to avoid imposition of any income or excise taxes on
     undistributed income of the Trust. The Trustee shall be authorized to rely
     conclusively upon the direction, and shall have no duty to make any
     additional distributions from the Trusts in the absence of such direction.
     The Trustee shall have no liability for any tax or other liability incurred
     by reason of action or inaction resulting from such direction. The fees of
     such agent designated by the Depositor shall be an expense of the Trusts
     reimbursable to the Trustee in accordance with section 8.05.

     (s) The following replaces the second paragraph of Section 3.08:

          In the event that an offer by the issuer of any of the Securities of
     any other party shall be made to issue new securities, or to exchange
     securities, for Trust Securities, the Trustee shall reject such offer.
     However, should any issuance, exchange or substitution be effected
     notwithstanding such rejection or without an initial offer, any securities,
     cash and/or property received shall be deposited hereunder and shall be
     promptly sold, if securities or property, by the Trustee; provided,
     however, if such securities are components of the applicable index, the
     Depositor may advise the Trustee to keep such securities. The cash received
     in such exchange and cash proceeds of any such sales shall, as the
     Depositor or its designee shall direct, be (1) reinvested into any
     Securities included in the applicable index or (2) distributed to
     Unitholders on the next Capital Distribution Date in the manner set forth
     in this Agreement regarding distributions from the Capital Account. Without
     limiting the generality of the foregoing, in determining whether such
     reinvestment is practicable, the Depositor may, but is not obligated to,
     specifically consider the ability of a Trust to reinvest such proceeds into
     round lots of a Security. Except as provided in Article VIII, the Trustee
     shall not be liable or responsible in any way for depreciation or loss
     incurred by reason of any such rejection or sale.

     (t) Section 3.06 shall be amended to read, in its entirety, as follows:


                                      -9-
<PAGE>


     Section 3.06.  Sale of Securities and Reinvestment. The Depositor by
     written notice may direct the Trustee to sell Securities at such price and
     time and in such manner as shall be deemed appropriate by the Depositor if
     the Depositor shall have determined that any one or more of the following
     conditions exist:

          (a) that there has been a default in the payment of principal of or
     interest on any outstanding debt obligations of the issuer of such
     Securities;

          (b) that the price of any such Security has declined to such an
     extent, as a result of adverse issuer credit factors, so that in the
     opinion of the Depositor the retention of such Securities would be
     detrimental to the interest of the Unitholders;

          (c) if a Trust has elected to be taxed as a "regulated investment
     company" as defined in the United States Internal Revenue Code of 1986, as
     amended, that such sale is necessary or advisable (i) to maintain the
     qualification of the Trust as a regulated investment company or (ii) to
     provide funds to make any distribution for a taxable year in order to avoid
     imposition of any income or excise taxes on undistributed income in the
     Trust;

          (d) that the Security has been removed from the applicable index; or

          (e) Depositor or its designee determines that such sale is
     appropriate.

          Upon receipt of such direction from the Depositor, the Trustee shall
     proceed to sell the specified Securities in such manner as the Depositor or
     its designee shall direct. The Depositor or its designee may enter into
     contracts on behalf of the Trust(s) to reinvest the proceeds of the sale of
     any Security sold pursuant to this section, Section 5.02 or otherwise
     pursuant to this Agreement into any Security included in the applicable
     index. Without limiting the generality of the foregoing, in determining
     whether such reinvestment is practicable, the Depositor may, but is not
     obligated to, specifically consider the ability of the Trust(s) to reinvest
     such proceeds into round lots of a Security. Contracts for sale or purchase
     of Securities shall be made by the Depositor on behalf of the Trust(s) or
     by such agent as the Depositor shall designate. The Depositor or its
     designee shall provide the Trustee such information as the Trustee may
     require in order to settle the transactions. The Trustee shall not be
     liable or responsible in any way for depreciation or loss incurred by
     reason of any sale or purchase made pursuant to any such direction or by
     reason of the failure of the Depositor to give any such direction, and in
     the absence of such direction the Trustee shall have no duty to sell or
     purchase any Securities under this Section 3.06 and shall have no
     responsibility for the composition of each Trust portfolio. The Depositor
     shall not be liable for errors of judgment in directing or failing to
     direct the Trustee pursuant to this Section 3.06. This provision, however,
     shall not protect the Depositor against

                                     -10-
<PAGE>


     any liability for which it would otherwise be subject by reason of willful
     misfeasance, bad faith or gross negligence in the performance of its duties
     or by reason of its reckless disregard of their obligations and duties
     hereunder.

          The Depositor or its designated agent shall make such reviews of each
     Trust portfolio as shall be necessary to maintain qualification of the
     Trust as a Regulated Investment Company and the Depositor shall be
     authorized to rely conclusively upon such reviews in directing sales
     pursuant to paragraph (c) of this section.

     (u) Paragraphs (a) and (b) of Section 3.10 shall be amended as follows:


          (a) The New Securities shall be a component of the applicable index.


          (b) The Depositor shall furnish a notice to the Trustee (which may
     be part of the Failed Contract Notice) in respect of the New Security
     purchased or to be purchased that shall (i) identify the New Securities,
     (ii) state that the contract to purchase, if any, entered into by the
     Depositor is satisfactory in form and substance and (iii) state that the
     foregoing conditions of clause (a) have been satisfied with respect to the
     New Securities.

Paragraph (c) of Section 3.10 shall be deleted.

     (v) Article III of the Standard Terms and Conditions of Trust is hereby
amended to add the following section:

     Section 3.14. License Fees.

          For the Nuveen Nasdaq 100 Index Portfolio ("Nasdaq 100 Trust") and
     pursuant to a Licensing Agreement between the Nasdaq Stock Market, Inc.
     ("Nasdaq") and the Depositor (the "Nasdaq"), as consideration for the
     licenses granted by Nasdaq for the right to use its trademarks and trade
     names or service marks, the Nasdaq 100 Trust will pay the fees provided for
     in the Nasdaq Agreement to Nasdaq or the Depositor to reimburse the
     Depositor for payment of the expenses.

          If the Nasdaq Agreement provides for an annual license fee computed in
     whole or in part by reference to the quarter-end asset balances of the
     Nasdaq 100 Trust, for purposes of calculating the accrual of estimated
     expenses, such annual fee shall accrue at a daily rate and the Trustee is
     authorized to compute an annual licensing fee payment (i) until the
     quarter-end in which the Depositor has informed the Trustee that there will
     be no further deposits of additional Securities, by reference to an
     estimate of the quarter-end asset balances which the Depositor shall
     provide the Trustee, and (ii) thereafter by reference to the previous
     quarter-end asset balance of the applicable Nasdaq 100 Trust. The Trustee
     shall adjust the net asset value (Trust Fund Evaluation) as of the dates
     specified in the preceding sentence to account for any variation between
     accrual of estimated license fees and the license fees payable pursuant to
     the Nasdaq Agreement, but such adjustment shall not affect calculations
     made prior thereto and no adjustment shall be made in respect thereof.

          Pursuant to a Licensing Agreement between Dow Jones and Company Inc.
     ("Dow Jones") and the Depositor (the "Dow Agreement"), for the Nuveen Dow
     Jones Global Titans Index Portfolio (the "Dow Index Trust"), as
     consideration for the licenses granted by Dow Jones for the right to use
     its trademarks and trade names or service marks, the Dow Index Trust will
     pay the fees set forth in the Dow Agreement to Dow Jones or the Depositor
     to reimburse the Depositor for payment of the expenses.

          If the Dow Agreement provides for an annual license fee computed in
     whole or in part by reference to the quarter-end asset balances for the Dow
     Index Trust, for purposes of calculating the accrual of estimated expenses,
     such annual fee shall accrue at a daily rate and the Trustee is authorized
     to compute an annual licensing fee payment (i) until the quarter-end in
     which the Depositor has informed the Trustee that there will be no further
     deposits of additional Securities, by reference to an estimate of the
     quarter-end asset balances which the Depositor shall provide the Trustee,
     and (ii) thereafter by reference to the previous quarter-end asset balance
     of the Dow Index Trust. The Trustee shall adjust the net asset value (Trust
     Fund Evaluation) as of the dates specified in the preceding sentence to
     account for any variation between accrual of estimated license fees and the
     license fees payable pursuant to the Dow Agreement, but such adjustment
     shall not affect calculations made prior thereto and no adjustment shall be
     made in respect thereof.


                                     -11-

<PAGE>


     (w) The following is added to the end of the first paragraph of Section
5.02.

     Sales of foreign securities shall be made in such manner and at such price
     as the Depositor, or its delegate, shall direct, and the Trustee shall not
     be liable or responsible for depreciation or loss incurred by reason of any
     sale made pursuant to such direction. If Securities in the Trust(s) are
     sold for the payment of the Redemption Price and there are excess proceeds
     remaining after meeting redemption requests, the Depositor or its designee
     may, but is not obligated to, direct the investment of such excess proceeds
     into any Securities included in the applicable index.

     (x) Section 5.03 shall be deleted.

     (y) The following paragraph shall be added to Section 9.01:

          Notwithstanding anything to the contrary herein, if at any time the
     applicable index shall no longer be compiled, maintained or made available,
     the Depositor may (a) direct that the Trust(s) created hereby continue to
     be operated hereunder utilizing the components of the applicable index as
     existed on the last date on which the applicable index components were
     available to a Trust or (b) direct the Trustee to terminate this Agreement
     and the Trusts created hereby and liquidate the Trusts in such manner as
     the Depositor shall direct.

     (z) The first paragraph of Section 10.01 shall be replaced with the
following paragraph:

     Section 10.01.  Amendment and Waiver. This Agreement may be amended from
     time to time by the Depositor and the Trustee without the consent of any of
     the Unitholders (a) to cure any ambiguity or to correct or supplement any
     provisions contained herein which may be defective or inconsistent with any
     other provision contained herein; (b) to change any provision hereof as may
     be required by the Securities and Exchange Commission or any successor
     governmental agency exercising similar authority; (c) to make such
     amendments as may be necessary for each Trust to continue to qualify as a
     regulated investment company for federal income tax purposes; or (d) to
     make such other provisions in regard to matters or questions arising
     hereunder as shall not adversely affect the interest of the Unitholders (as
     determined in good faith by the Depositor and the Trustee). This Agreement
     may also be amended from time to time by the Depositor and the Trustee (or
     the performance of any of the provisions of this Agreement may be waived)
     with the consent of holders of Units representing 66-2/3% of the Units at
     the time outstanding under the Trust Agreement of the individual Trust Fund
     or Trust Funds affected for the purpose of adding any provisions of this
     Agreement or of materially modifying in any manner the rights of the
     holders of Units of such Trust Fund or Trust Funds; provided, however, that
     in no event may any amendment be made which would (a) alter the rights to
     the Unitholders as against each other, (b) provide the Trustee with the
     power to engage in business or investment activities other than as
     specifically provided in this Agreement or (c) adversely affect the
     characterization of the Trust as a regulated investment company for federal
     income tax purposes; provided, further, that the consent of 100% of the
     Unitholders of any individual Trust Fund is required to amend

                                     -12-
<PAGE>


     this Agreement (a) to reduce the aforesaid percentage of Units the holders
     of which are required to consent to certain amendments and (b) to reduce
     the interest in such Trust Fund represented by any Units of such Trust
     Fund.

     (aa) Article III of the Standard Terms and Conditions of Trust is hereby
     amended to add the following section:

          Section 3.15. Foreign Currency Exchange. Unless the Depositor shall
otherwise direct, whenever funds are received by the Trustee in foreign
currency, upon the receipt thereof or, if such funds are to be received in
respect of a sale of Securities, concurrently with the contract of the sale for
the Security (in the latter case the foreign exchange contract to have a
settlement date coincident with the relevant contract of sale for the Security),
the Trustee shall enter into a foreign exchange contract for the conversion of
such funds to U.S. dollars pursuant to the instruction of the Depositor. The
Trustee shall have no liability for any loss or depreciation resulting from
action taken pursuant to such instruction.




     (bb) Section 8.01 shall be amended to add the following as paragraph (1):

          (1) The Trustee except by reason of its own negligence or willful
misconduct shall not be liable for any action taken or suffered to be taken by
it in good faith and believed by it to be authorized or within the discretion or
rights or powers conferred upon it by this Indenture.

                                     -13-
<PAGE>


          In Witness Whereof, John Nuveen & Co. Incorporated, has caused this
Trust Indenture and Agreement for Nuveen Unit Trusts, Series 81 to be executed
by its President, one of its Vice Presidents or one of its Assistant Vice
Presidents and its corporate seal to be hereto affixed and attested by its
Secretary or its Assistant Secretary and The Chase Manhattan Bank has caused
this Trust Indenture and Agreement to be executed by one of its Vice Presidents
or Second Vice Presidents and its corporate seal to be hereto affixed and
attested to by one of its Assistant Treasurers; all as of the day, month and
year first above written.
                                       John Nuveen & Co. Incorporated,
                                                   Depositor


                                       By /s/ Benjamin T. Fulton
                                          ----------------------------
                                              Authorized Officer


(Seal)

Attest:

By /s/ Nicholas Dalmaso
   -------------------------
       Assistant Secretary

                                       The Chase Manhattan Bank, Trustee


                                       By /s/ James P. Donovan
                                          ----------------------------
                                              Assistant Vice President


(Seal)

Attest:

By /s/ Rachelle Cohen
   --------------------------
       Assistant Treasurer

                                     -14-
<PAGE>


                Schedule A to the Trust Indenture and Agreement

                        Securities Initially Deposited

                                      in

                         Nuveen Unit Trusts, SERIES 81



    (Note:  Incorporated herein and made a part hereof is the "Schedule of
            Investments" as set forth for the Trust(s) in the Prospectus.)

                                     -15-

<PAGE>
                                                                     Exhibit 3.1

                              February 17, 2000


John Nuveen & Co. Incorporated
333 West Wacker Drive
Chicago, Illinois  60606


     Re:                 Nuveen Unit Trusts, Series 81
                         -----------------------------


Gentlemen:


     We have served as counsel for you, as Depositor of Nuveen Unit Trusts,
Series 81 (hereinafter referred to as the "Fund"), in connection with the
issuance under the Trust Indenture and Agreement dated the date hereof between
John Nuveen & Co. Incorporated, as Depositor, and The Chase Manhattan Bank, as
Trustee, of Units of fractional undivided interest in the one or more Trusts of
said Fund (hereinafter referred to as the "Units").


     In connection therewith, we have examined such pertinent records and
documents and matters of law as we have deemed necessary in order to enable us
to express the opinions hereinafter set forth.

     Based upon the foregoing, we are of the opinion that:


     1.  The execution and delivery of the Trust Indenture and Agreement and the
 establishment of book entry positions and the execution and issuance of
 certificates evidencing the Units in the Trust(s) of the Fund have been duly
 authorized; and

     2.  The book entry positions and certificates evidencing the Units in the
 Trust(s) of the Fund when duly established or duly executed and delivered by
 the Depositor and the Trustee in accordance with the aforementioned Trust
 Indenture and Agreement, will constitute valid and binding obligations of such
 Trust(s) and the Depositor in accordance with the terms thereof.

     We hereby consent to the filing of this opinion as an exhibit to the
Registration Statement (File No. 333-95751) relating to the Units referred to
above and to the use of our name and to the reference to our firm in said
Registration Statement and in the related Prospectus.


                                     Respectfully submitted,


                                     /s/ Chapman and Cutler
                                     ----------------------
                                     Chapman and Cutler
EFF:ps

<PAGE>


                   [Letterhead of Carter, Ledyard & Milburn]

                                                                     Exhibit 3.2

                               February 17, 2000

The Chase Manhattan Bank,
  as Trustee of
Nuveen Unit Trusts, Series 81
Nuveen-NASDAQ 100 Index Portfolio, February 2000
Nuveen-Dow Jones Global Titans Index(SM), February 2000
4 New York Plaza, 3rd Floor
New York, New York 10004

Attention: Mr. Steven B. Wolinsky
           Senior Vice President

     Re:  Nuveen Unit Trusts, Series 81
          Nuveen-NASDAQ 100 Index Portfolio, February 2000
          Nuveen-Dow Jones Global Titans Index(SM),
          February 2000
          ----------------------------------------------------

Dear Sirs:

     We are acting as counsel for The Chase Manhattan Bank ("Chase") in
connection with the execution and delivery of a Standard Terms and Conditions of
Trust for Nuveen Unit Trusts Series 4 and certain subsequent Series dated May
29, 1997 and a related Trust Indenture and Agreement dated today's date (such
Standard Terms and Conditions of Trust and related Trust Indenture and Agreement
are collectively referred to as the "Indenture"), each between John Nuveen & Co.
Incorporated, as Depositor (the "Depositor"), and Chase, as Trustee (the
"Trustee"), establishing the Nuveen Unit Trusts, Series 81, Nuveen-NASDAQ 100
Index Portfolio, February, 2000 and Nuveen-Dow Jones Global Titans Index(SM),
February 2000 (each a "Trust Fund"), and the confirmation by Chase, as Trustee
under the Indenture, that it has caused to be credited to the Depositor's
account at The Depository Trust Company a number of units constituting the
entire interest in the Trust Fund (such aggregate units being herein called
"Units") each of which represents an undivided interest in such Trust Fund,
which consists of common stocks (including confirmations of contracts for the
purchase of certain stock not yet delivered and cash, cash equivalents or an
irrevocable letter of credit in the amount required for such purchase upon the
receipt of such stock), such stocks being defined in the Indenture as Securities
and referenced in the schedules to the Indenture.
<PAGE>

     We have examined the Indenture, the Closing Memorandum executed and
delivered today by the Depositor and the Trustee (the "Closing Memorandum"), the
form of certificate for the Units included in the Indenture and a specimen of
the certificates to be issued thereunder (the "Certificates") and such other
documents as we have deemed necessary in order to render this opinion. Based on
the foregoing, we are of the opinion that:

          1.  Chase is a duly organized and existing corporation having the
     powers of a trust company under the laws of the State of New York.

          2.  The Indenture has been duly executed and delivered by Chase and,
     assuming due execution and delivery by the Depositor, constitutes the valid
     and legally binding obligation of Chase.

          3.  The Certificates are in proper form for execution and delivery by
     Chase, as Trustee.

          4.  Chase, as Trustee, has registered on the registration books of
     the Trust Fund the ownership of the Units by The Depository Trust Company,
     where it has caused the Units to be credited to the account of the
     Depositor. Upon receipt of confirmation of the effectiveness of the
     registration statement for the sale of the Units filed with the Securities
     and Exchange Commission under the Securities Act of 1933, the Trustee may
     cause the Units to be transferred on the registration books of the Trust
     Fund to such other names, and in such denominations, as the Depositor may
     order, and may deliver Certificates evidencing such ownership as provided
     in the Closing Memorandum.

          5.  Chase, as Trustee, may lawfully advance amounts to the Trust Fund
     and may be reimbursed, without interest, for any such advances from funds
     in the income and capital accounts, as provided in the Indenture.

     In rendering the foregoing opinion, we have not considered, among other
things, whether the Securities have been duly authorized and delivered.

                              Very truly yours,


                              /s/ CARTER, LEDYARD & MILBURN
                              -----------------------------
                              CARTER, LEDYARD & MILBURN

<PAGE>


                                     [On Letterhead of The Chase Manhattan Bank]


                                                                     Exhibit 4.2




                               February 17, 2000



John Nuveen & Co. Incorporated
333 West Wacker Drive
Chicago, IL 60606

     Re:  Nuveen Unit Trust, Series 81

Dear Sirs:

     The Chase Manhattan Bank is acting as Evaluator for the series of Nuveen
Unit Trust set forth above (the "Trust"). We enclose a list of the Securities to
be deposited in the Trust on the date hereof. The prices indicated therein
reflect our evaluation of such Securities as of close of business on February
16, 2000 in accordance with the valuation method set forth in the Standard Terms
and Conditions of Trust for Nuveen Unit Trust Series 4 and subsequent. We
consent to the reference to The Chase Manhattan Bank as the party performing the
evaluations of the Trust Securities in the Registration Statement (No. 333-
95751) filed with the Securities And Exchange Commission with respect to the
registration of the sale of the Trust Units and to the filing of this consent as
an exhibit thereto.
                                     Very Truly Yours,

                                     /s/ Rachelle Cohen
                                     -----------------------

                                     Rachelle Cohen

                                     Assistant Treasurer
EFF:ps


<PAGE>

                                  Memorandum

                    Re:  Nuveen Unit Trusts, Series 81

     The list of securities comprising each trust of the fund, the evaluation,
record and distribution dates and other changes pertaining specifically to the
new series, such as size and number of units of the trusts in the fund and the
statement of condition of the new fund will be filed by amendment.

                                   1940 Act

                             Forms N-8A and N-8B-2

     Form N-8A and Form N-8B-2 were filed in respect of Nuveen Unit Trusts,
Series 1 (File No. 811-08103).

                                   1933 Act

                                 The Indenture

     The form of the proposed Trust Indenture and Agreement is expected to be in
all respects consistent with the form of Trust Indenture and Agreement dated May
29, 1997 relative to Nuveen Unit Trusts, Series 4.

                               /s/ Chapman and Cutler

                               Chapman and Cutler

Chicago, Illinois

January 31, 2000


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