NUVEEN UNIT TRUSTS SERIES 81
497J, 2000-02-18
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                                                               February 18, 2000

(ON JOHN NUVEEN & CO. INCORPORATED LETTERHEAD)

SECURITIES AND EXCHANGE COMMISSION
450 FIFTH STREET, N.W.
WASHINGTON, D.C. 20549

RE:  Nuveen Unit Trusts, Series 81

     File No. 333-95751

     Dear Sir or Madam:

     On behalf of John Nuveen & Co. Incorporated, in accordance with the
     provisions of Rule 497(j) of Regulation C under the Securities Act of 1933
     (the "Securities Act"), this letter serves to certify that the most recent
     amendment to the Registration Statement on Form S-6 (the "Registration
     Statement") of the above-referenced Series does not differ from that which
     would have been filed pursuant to Rule 497(b) of the Securities Act.
     Amendment No. 1, which was the most recent amendment to the Registration
     Statement, was filed electronically with the Commission on February 17,
     2000.

     John Nuveen & Co. Incorporated

     By /s/ Thomas C. Muntz
        ----------------------
        Thomas C. Muntz
        Vice President



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