ADVANCED BUSINESS SCIENCES INC/DE
10SB12G, 1999-06-22
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                      SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, DC 20549

                                  FORM 10-SB

                       Advanced Business Sciences, Inc.
                (Name of Small Business Issuer in its charter)


               DELAWARE                                87-0347787
       (State of incorporation)             (IRS Employer Identification No.)

3345 No. 107th Street, Omaha, Nebraska                    68134
(Address of principal executive offices)               (Zip Code)


                  Issuer's telephone number: (402) 498-2734

      Securities to be registered under Section 12(b) of the Act: None.

         Securities to be registered under Section 12(g) of the Act:

                  Common Stock (par value $0.001 per share)
                               (Title of class)


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                              TABLE OF CONTENTS

                                                                          Page


PART  I......................................................................1
      Item 1 Description of Business..........................................1
                  (a)   Business Development.................................1
                  (b)   Business of Issuer...................................2
                        (i)   Introduction  .................................2
                        (ii)  The Electronic Monitoring Market...............3
                        (iii) Competition....................................4
                        (iv)  Business Strategy..............................4
                        (v)   The Products and Services of the Company.......5
                        (vi)  The Technology.................................6
                        (vii) Intellectual Property Rights...................8
                        (viii) Regulation....................................8
                        (ix)  Research and Development.......................9
                        (x)   Customers; Orders Backlog......................9
                        (xi)  Seasonality....................................9
                  (c)   Reports to Security Holders..........................9
      Item 2 Management's Discussion and Analysis or Plan of Operation.......10
                  (a)   Revenue ............................................11
                  (b)   Cost of Sales.......................................11
                  (c)   Gross Profit .......................................12
                  (d)   Expenses Research and Development...................12
                  (e)   Sales and Marketing.................................12
                  (f)   General and Administrative .........................13
                  (g)   Profit (loss) from Operations.......................13
                  (h)   Interest Expense....................................13
                  (i)   Asset Abandonment Charge............................14
                  (j)   Net Loss............................................14
                  (k)   Liquidity and Capital Resources.....................14
                  (l)   Impact of Year 2000 Issues..........................14
      Item 3 Description of Property.........................................15
      Item 4 Security Ownership of Certain Beneficial Owners and Management..16
      Item 5 Directors, Executive Officers, Promoters and Control Persons....17
      Item 6 Executive Compensation..........................................19
      Item 7 Certain Relationships and Related Transactions..................20
      Item 8 Description of Securities.......................................20
                  (a)   General.............................................20
                  (b)   Common Shares.......................................20
                  (c)   Preferred Stock.....................................21

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                  (d)   No Preemptive Rights................................21
                  (e)   Delaware Business Combination Statute...............21
                  (f)   Certain Charter Provisions..........................22
                        (i)   General ......................................22
                        (ii)  Number of Directors; Removal; Vacancies ......22
                        (iii) Classified Board of Directors ................22
                        (iv)  Approval of Repurchases ......................23
                        (v)   Amendments to Bylaws .........................23
                        (vi)  Amendment of the Certificate of Incorporation 23
                  (g)   Limitation of Liability and Indemnification.........23
                  (h)   Transfer Agent and Registrar........................24

PART  II..................................................................II-1
      Item 1 Market Price of and Dividends on the Company's Common Equity and
             Other Shareholder Matters......................................II-1
      Item 2 Legal Proceedings..............................................II-1
      Item 3 Changes in and Disagreements with Accountants..................II-2
      Item 4 Recent Sales of Unregistered Securities........................II-2
      Item 5 Indemnification of Directors and Officers......................II-3

PART F/S...................................................................F/S-1

PART  III..................................................................III-1
      Item 1 Index to Exhibits.............................................III-1
      Item 2 Description of Exhibits.......................................III-1

SIGNATURES...............................................................III-1


                                     iii

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                                    PART I.

Item 1. Description of Business

      (a)   Business Development

      ADVANCED BUSINESS SCIENCES, INC. ("ABS" or the "Company") is a development
stage  company.  The Company  develops,  produces,  markets and supports a broad
product line of solutions relating to the tracking,  monitoring and reporting of
individuals  and things.  ABS  products  are  designed to enhance  productivity,
reduce costs,  and improve overall  response using on-line access to information
previously  maintained  on a variety  of media.  Today,  the  Company  primarily
markets to the criminal justice application for house arrest (HA) and continuous
electronic  monitoring (CEM). ABS currently serves the criminal justice industry
and individual monitoring within eleven (11) states: Arizona,  Minnesota,  Iowa,
New Jersey,  Ohio, Texas,  Wisconsin,  Colorado,  South Carolina,  New York, and
Kansas.

      The  Company was  incorporated  under the laws of the State of Colorado on
June 13,  1983 under the name "Sage  Institute  International,  Inc." A Delaware
corporation under the name "Sage Analytics International, Inc." was incorporated
on July 17, 1986; and, on September 2, 1986, the Company was reincorporated as a
Delaware  corporation  by merging  the  Colorado  corporation  with and into the
Delaware corporation.

      On December 17, 1997,  the  shareholders  of Advanced  Business  Sciences,
Inc., a Nebraska  corporation,  concluded a share exchange with the Company (the
"Share  Exchange")  whereupon the Nebraska  corporation  became the wholly-owned
subsidiary  of the Company and  control of the  Company was  transferred  to the
shareholders  of the Nebraska  corporation.  See "Security  Ownership of Certain
Beneficial Owners and Management," "Directors, Executive Officers, Promoters and
Control  Persons," and "Recent Sales of  Unregistered  Securities."  The Company
changed its name to Advanced Business Sciences, Inc. on December 18, 1997.

      On  September  28,  1998,  the  Company  concluded a share  exchange  with
Comguard  Leasing  and  Financial,  Inc.,  an  Illinois  corporation,   and  its
shareholders  (the  "Comguard   Acquisition").   The  Comguard  Acquisition  was
rescinded  effective June 1, 1999, and the Company  acquired  selected assets in
exchange  for  advances  made to  Comguard  Leasing and  Financial,  Inc. or its
subsidiary, Comguard, Inc.

      (b)   Business of Issuer

            (i)   Introduction

            The Company was initially engaged in the commercial application of a
form of decision support technology which incorporated  proprietary  methodology
and  software.  This  technology  was  marketed to both  government  and private
industry. The Company conducted no business operations

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from in or about April,  1996, until the completion of the Share Exchange.  Upon
completion of the Share Exchange, the Company commenced operations once again as
described below.

            The Company designs, develops, produces, sells and supports wireless
products and services  relating to the  tracking,  monitoring  and  reporting of
individuals and things.  Currently,  the Company's  business relates to criminal
justice applications for house arrest and electronic monitoring.

            The ABS<ComTrak(R) product, which utilizes Global Positioning System
("GPS") technology,  wireless  communications and proprietary computer software,
provides  real time  monitoring,  tracking  and  reporting of adult and juvenile
offenders as a criminal justice rehabilitative  alternative.  Through controlled
monitoring in ABS or customer staffed operations centers,  the system tracks the
geographic location of every offender in the system, reports specific activities
and  identifies  violations  against   customer-established   parameters.   This
information  is then  delivered to the  appropriate  authorities  using  various
methods,  including  telephone  calls,  paging  and  internet-based  e-mail  and
web-based  reports.  The  Company  believes  use  of  its  system  can  offer  a
substantial  cost  savings  over  the  cost of  incarceration  and  improve  the
efficiency  of  probation  and parole  officers.  It also offers the  backlogged
criminal  justice  systems a more  secure  solution  to the  problems of rapidly
growing  criminal  populations,  overcrowded  correctional  facilities  and more
lenient sentencing alternatives.

            In addition to the criminal justice market, the Company has targeted
additional  industries  where  it  believes  its  products  and  services  offer
attractive solutions to current problems.
These markets are as follows:


    Industry                   Applications
    --------                   ------------



 Transportation          Automatic vehicle tracking
                         Payload status

   Healthcare            Emergency response services
                         Tracking of infants and Alzheimer's patients


            The monitoring and reporting operations of the Company are conducted
through ABS Nebraska, Inc., a Nebraska corporation ("ABS Nebraska"),  the direct
subsidiary of the Company.  The Company has twenty-two  (22) full time employees
and one (1) part-time employee.

            (ii)  The Electronic Monitoring Market

            To  date,  the  Company  has  focused   primarily  upon   electronic
monitoring  in the  criminal  justice  system.  In  1980,  the  total  estimated
correctional  population  was,  according  the United  States  Bureau of Justice
Statistics,  1.8 million. In 1996, that number was 5.5 million.  This growth has
resulted  in  obvious  stresses  on the  correctional  system  in  terms of both
management  and costs.  While this has led to  increased  use of  probation  and
parole as  alternatives  to  incarceration,  caseworkers  are  unable to monitor
probationers  and  parolees  effectively.  Electronic  monitoring  enhances  the
ability

                                      2

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of caseworkers to monitor the activities of probationers  and parolees,  as well
as affording house arrest as an economic alternative to incarceration.

            The  traditional  house  arrest  application  utilizes  (1) a  fixed
location radio frequency ("RF") device connected to a power source and telephone
line (an "HAU") and (2) a  tamper-proof  transmitter  cuff worn by the offender.
The individual under house arrest must remain within a specified distance of the
HAU. When they leave that proximity,  the HAU transmits a notification  over the
telephone  line to a  monitoring  center.  The  monitoring  center  software and
operators determine if this is a permitted or authorized departure, using tables
of  individual  schedules  provided  by the  contracting  authorities.  If  they
determine it is a violation of the programmed  schedule,  a violation  notice is
created and the  appropriate  authorities  are contacted  using  pre-established
protocols.  These protocols can include voice calls, paging,  faxing,  e-mail or
some combination. Additionally, reports are created for transmission as required
by the customer organization.

            HAU equipment first became commercially  available in 1984. In 1987,
twenty-one (21) states reported using this electronic monitoring as a sentencing
alternative.  By 1995,  all fifty states were using at least limited  amounts of
house arrest  electronic  monitoring.  Experts  estimate that as many as 300,000
individuals  now  incarcerated  could be supervised  more  cost-effectively  and
safely using appropriate electronic supervision.  There were an estimated 95,000
individuals  under  electronic  house  arrest at the  beginning  of 1998.  These
individuals were monitored primarily through third party service providers under
contract to the appropriate local, state and federal agencies.

            The Company believes there is a substantial opportunity to provide a
mobile system to monitor  offenders in the community  environment  away from the
fixed HA  location.  ABS has  pioneered  the  development  of a mobile  Personal
Tracking Unit ("PTU") system which provides continuous  monitoring away from the
fixed location, utilizing GPS locational information and wireless communications
technologies.  ABS is a leader in the field  deployment of such  systems.  As of
March 31, 1999, the Company had approximately  forty (40) of its PTU's in use in
the criminal justice system in Arizona, Texas, Ohio, Wisconsin and Iowa.

            (iii) Competition

            Today, there are several companies providing  monitoring services on
a  nation-wide  basis,  including  BI  Incorporated  ("BI"),   SecurityLink  (an
Ameritech company),  and General Security Services Corp. In addition,  there are
many smaller  companies  that provide  monitoring  services on a local basis for
smaller  governmental  agencies.  BI is  believed  to  be  the  largest  company
monitoring  offenders in the criminal  justice  market,  with a reported  21,500
active units as of March 31, 1999.

            There are also other  companies  which  provide HA equipment  and at
least two others with GPS-based  systems.  BI has historically  been the largest
provider of the equipment in use today. However, the Company believes that BI is
no longer  offering its equipment for sale except in connection  with  contracts
which engage it to provide  monitoring  services.  Other companies  producing HA
equipment include ElmoTech, Comguard, Digital Products Corporation, and Tracking
Systems Corporation.

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            ABS believes that only one other company, Pro Tech Monitoring, Inc.,
has a GPS-based product in the field today. BI, however,  has announced plans to
introduce a GPS-based product in 1999.

            (iv)  Business Strategy

            The key elements of the Company's business strategy are:

            o     Be a leader in applying GPS  technology  to  applications  for
                  tracking  people and  assets.  The  Company  believes it has a
                  leadership  position today, and has invested  substantially in
                  efforts to improve its  products.  Improvements  in technology
                  components  and  communications  systems are being  constantly
                  evaluated.  The Company intends to incorporate appropriate new
                  or  improved  capabilities  into its  products  on an  ongoing
                  basis, and to continue to devote significant  resources to the
                  area of product development.

            o     Target  application   opportunities   within  specific  market
                  niches,  to be a supplier of  equipment  and software to those
                  end  markets.  The  Company  believes  that it is a leader  in
                  applying  GPS  technology   today  in  the  criminal   justice
                  marketplace.  It intends to  capitalize  on that  position  by
                  targeting  the  service  providers  that need  additional  and
                  replacement  HA  equpment  and who have a need  for  GPS-based
                  systems.

                  GPS technology,  in general,  has already gained acceptance in
                  the  automatic   vehicle   location  ("AVL")  segment  of  the
                  transportation industry and ABS believes that its core product
                  can be  readily  adapted  to  that  market.  The  Company  has
                  targeted  the location of  untethered  trailers as one initial
                  application niche to serve in the transportation industry. ABS
                  believes  that  its  products  have  application   within  the
                  healthcare  industry and has targeted  segments of the newborn
                  infant care and senior care as initial market opportunities.

                  Additionally,  the Company  will  maintain the  capability  to
                  undertake  special projects,  funded by specific  customers to
                  meet their unique needs.  These special  projects will be done
                  to advance  ABS's  knowledge  in targeted  markets and to fund
                  development within specific application areas.

            o     Partner  with  world-class  organizations  that can assist the
                  Company in the development  and  distribution of its products.
                  The Company will  maintain  certain core  competencies  on its
                  staff,   including  the  senior  technology   knowledge,   and
                  knowledge  specific to managing its production,  distribution,
                  and  sales  functions.  Part of the  business  strategy  is to
                  identify  partner  companies  in  the  areas  of  engineering,
                  manufacturing,  technology,  communications  and distribution.
                  These companies will be best-of-class and

                                      4

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                  derive their revenue and profit  opportunities  in application
                  areas in parallel with ABS.

            (v)   The Products and Services of the Company

            The Company markets the ABS<ComTrak(R)  solution. The ABS<ComTrak(R)
solution provides its customers  real-time  monitoring of any person or thing on
either a continuous or periodic basis, whether the person or object is moving or
is at a fixed location.

            The ABS<ComTrak(R) solution consists of four basic components:

                  A Personal Tracking Unit ("PTU") is worn by or placed near the
subject.  The PTU is secured to the subject via a Wireless Cuff ("WC"), which is
about the size of many wrist watches.  The WC is waterproof and shockproof;  its
case and strap are designed to be tamper resistant. The PTU utilizes information
from  the GPS to  triangulate  the  subject's  physical  position.  The PTU then
transmits this and other information to an Operations  Center. In addition,  the
PTU can be used in a docking station as a Home Arrest Monitor ("HAM").

                  The PTU  monitors  the status of the WC and itself and reports
to the Operations Center (see below) the following conditions:


   o       Status of radiofrequency contact between PTU and HAM,
          including proximity violations (i.e. failure to remain within
          specified proximity of HAM)

   o       Tampering with PTU or HAM

   o       Status of communications between HAM and Operations
          Center

   o       Status of power connection of HAM

   o       Status of PTU battery

   o       Exclusion zone violations (i.e., being in an area or location
          from which the subject is prohibited)


                  ABS Nebraska operates an Operations Center (the "OC") 24 hours
per day,  7 days per week.  The OC  monitors  the  HAM's and PTU's and  provides
technical support to customers.

                  Each customer  maintains a Customer  Workstation ("CW") at its
site.  The CW is used by the  customer  to build  daily  schedules  and  program
inclusion and exclusion zones. Six levels of service are provided by the Company
to meet the specific needs of its customers.


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            (vi)  The Technology

                  (A)   Wireless Services and their Regulation

                  Wireless  communications are transmitted through the space via
radiofrequency radiation, one of several types of electromagnetic radiation. The
RF part of the electromagnetic  spectrum is generally defined as electromagnetic
radiation with  frequencies  in the range of 3 kilohertz to 300  gigahertz.  One
"hertz" equals one cycle per second. A kilohertz  ("kHz") is one thousand hertz,
a megahertz  ("mHz") is one million hertz and a gigahertz ("gHz") is one billion
hertz.  Microwave  radiation is a  high-frequency  form of RF usually defined as
from about 300 mHz to 300 gHz.

                  Familiar  uses of RF involving  telecommunications  include AM
and FM radios,  television,  citizens  band  radio,  hand-held  walkie  talkies,
amateur   radio,   short-wave   radio,   cordless   telephones   and   microwave
point-to-point     and     ground-to-satellite     telecommunications     links.
Non-telecommunications applications include microwave ovens and radar.

                  The  manufacture,  sale and use of devices  which  utilize any
part of the RF spectrum are subject to  regulation.  The Federal  Communications
Commission (the "FCC") is the principal  agency  responsible for such regulation
within the United States.  State and local governments,  however,  exercise some
control  respecting the siting of wireless  facilities.  While many transmitters
(such  as radio  stations)  must be  individually  licensed,  certain  low-power
transmitters  need  not  be.  These  would  include  such  devices  as  cordless
telephones,  baby monitors, garage door openers, wireless home security systems,
and keyless  automobile  entry  systems.  Before such a device may be  marketed,
however,  it  must  first  be  tested  to  determine  if the  device  meets  FCC
specifications  and then receive  authorization  from the FCC. The devices which
the Company markets fit within this regulatory scheme.

                  (B)   Global Positioning System

                  The Global  Positioning System ("GPS") consists of at least 24
operational  satellites  that orbit the earth  every 12 hours.  Operated  by the
Department of Defense,  this constellation  typically permits from five to eight
satellites  to be visible from any point on earth at any given moment in time. A
master control facility located at Schriever Air Force Base in Colorado monitors
signals from the  satellites  and uploads  orbital and clock data.  Users of GPS
convert signals from four different satellites to compute position and time.

                  Only authorized users of GPS with specially equipped receivers
are permitted to use the Precise  Positioning  System  ("PPS").  PPS is accurate
within 22 meters for horizontal position,  27.7 meters for vertical position and
100 nanoseconds time accuracy. On the other hand, civil users of GPS such as the
Company are  permitted  to use the Standard  Positioning  Service  ("SPS").  The
accuracy of SPS is  intentionally  degraded by the Department of Defense using a
technique  referred to as  selective  availability.  SPS is accurate  within 100
meters for horizontal

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position,  156 meters for vertical  position and 340 nanoseconds  time accuracy.
SPS is available 24 hours per day without charge or  restrictions on a worldwide
basis.

                  To correct  the  errors  created  by  selective  availability,
methods have been developed which are generally  referred to as Differential GPS
("DGPS")  techniques.  DGPS  corrects  errors at one location with measured bias
errors at a known  position.  A reference  receiver (or base  station)  computes
corrections  for each satellite  signal.  Corrections may then be transmitted by
radio  link or other  electronic  means.  The U.S.  Coast  Guard,  for  example,
maintains a network of differential monitors and transmits DGPS corrections over
radiobeacons  covering  much of the U. S.  coastline.  Private DGPS services are
also  available,  some  of  which  require  payment  of a user  fee.  PTU's  are
configured  to use SPS.  PTU's may be  configured  to use DGPS if  customers  so
desire.

                  On March 29, 1996, a Presidential directive (the "Presidential
Directive") announced that it is the policy of the U.S. Government that the U.S.
would continue to provide SPS for peaceful civil,  commercial and scientific use
on a continuous,  worldwide basis,  free of direct user fees, but that selective
availability  would be  discontinued  within ten years. On January 25, 1999, the
Vice President  announced a budgetary  initiative to modernize GPS by adding two
new civil signals to future GPS satellites.

                  GPS satellites  and their ground  support  systems are complex
electronic  systems  subject to electronic and mechanical  failures and possible
sabotage.  The  satellites  have  design  lives of 7.5 years and are  subject to
damage by the hostile space environment in which they operate. To repair damaged
or  malfunctioning  satellites is not  economically  feasible.  If a significant
number of  satellites  were to become  inoperable,  there could be a substantial
delay before they are replaced with new satellites. A reduction in the number of
operating  satellites would impair the current utility of the GPS system and the
growth of current and additional market opportunities. In addition, there can be
no assurance that the U.S. government will remain committed to the operation and
maintenance  of GPS satellites  over a long period,  or that the policies of the
U.S.  Government  for the  use of GPS  without  charge  will  remain  unchanged.
However, the Presidential Directive marks the first time in the evolution of GPS
that access for consumer,  civilian and commercial use has a solid foundation in
law.  Because of  ever-increasing  commercial  applications  of GPS,  other U.S.
Government  agencies may become involved in the administration or the regulation
of the  use of GPS  signals.  Any of the  foregoing  factors  could  affect  the
willingness  of buyers of the  Company's  products to select  GPS-based  systems
instead of products  based on competing  technologies.  Any resulting  change in
market  demand for GPS  products  could have a  material  adverse  effect on the
Company's financial results.

                  A recent study by the Johns Hopkins University Applied Physics
Laboratory  (January,  1999)  examined the  susceptibility  of GPS  equipment to
intentional or inadvertent signal  interference.  This study concluded that only
intentional   interference   (i.e.,   jamming)   and   ionospheric   errors  and
scintillation  represented any significant risk. Such risks,  however,  could be
reduced using various mitigation  techniques;  and, moreover,  such interference
would  most  likely  be short in  duration.  Nevertheless,  concerns  about  the
integrity of GPS could translate into reduced demand for the Company's  products
and services.

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            (vii) Intellectual Property Rights

            The Company has three pending U.S. Patent Applications  covering its
technology.  Two  of  the  patent  applications  cover  a  system  for  remotely
monitoring an  individual,  and for  providing  real time  notification  if that
individual fails to comply with predetermined conditions.  The third application
covers a unique antenna for use with the system.

            The  Company  has  been  granted  a  nonexclusive,   nontransferable
software license from SiRF Technology  Incorporated ("SiRF").  SiRF has designed
GPS chip sets and software solutions that allow ABS to embed GPS technology into
its products.  This license may be terminated if SiRF loses any of its rights as
to the software products encompassed therein or by either party upon thirty (30)
days  written  notice in the event of a  material  breach of the  license by the
other party.

     The  Company  has  acquired  from  Electronic  Rainbow,   Inc.  all  rights
respecting  monitoring  software,  hardware and firmware developed by Electronic
Rainbow,  Inc. The Company has granted Electronic  Rainbow,  Inc. a nonexclusive
license to use such  software,  hardware  and  firmware in  connection  with the
healthcare industry.

            (viii) Regulation

     The  manufacture,  sale and use of RF devices is  regulated by the FCC. See
Item  1(b)(vi)(A) of this Part I.  Similarly,  insofar as GPS remains funded and
controlled  by the U. S.  government,  devices  utilizing  GPS must conform with
government specifications.

            The use of tracking devices as an aid to, or indeed  substitute for,
physical surveillance by law enforcement personnel, is subject to federal, state
and  local  law.  Generally  stated,  tracking  devices  may be  attached  to or
installed upon the monitored person or object without court order as long as the
person or object  remain in public view.  Once the person or object is withdrawn
from public view, a court order is required.  But,  where a tracking  device has
been placed with contraband  (e.g.,  stolen goods),  rather than with a lawfully
possessed  item,  warrantless  monitoring  can  continue to occur even after the
monitored  object has been taken onto private  premises.  As a rule, all persons
presently  monitored by the Company are subject to a court order  requiring such
monitoring as a condition to their release.

            The use of tracking  devices by private  persons is also  subject to
applicable  law. The  monitoring of persons  without their consent or of objects
without their owners' or lawful  possessors'  consent may be a violation of laws
protecting privacy and property rights.

            (ix)  Research and Development

            During 1997 and 1998,  the Company  expended  $32,065 and  $468,563,
respectively,  toward research and  development.  The costs of such research and
development are borne by the Company and not by any of its customers.


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            (x)   Customers; Orders Backlog

            Because the Company is a development  stage company,  it has to date
sustained  significant  losses.  The loss of any customer  could have a material
adverse  effect upon the  prospects  and  business of the  Company.  There is no
material backlog of orders for products of the Company.

            (xi)  Seasonality

            The Company's business is not seasonal.

      (c)   Reports to Security Holders

      The Company is  voluntarily  filing this  Registration  Statement  on Form
10-SB in order to make information  concerning  itself more readily available to
the  public.  Management  believes  that  being a  reporting  company  under the
Securities  Exchange Act of 1934 (the "Exchange Act") could provide existing and
prospective investors with additional  information  concerning the Company. As a
result of filing this Registration  Statement,  the Company will be obligated to
file interim and periodic  reports with the Securities  and Exchange  Commission
(the  "Commission")  in accordance with the Exchange Act. The Company intends to
continue to file these periodic  reports under the Exchange Act voluntarily even
if its obligation to file such reports is suspended under applicable  provisions
of the Exchange Act.

      The reports and other  information  filed by the Company may be  inspected
and  copied  at  prescribed  rates at the  public  reference  facilities  of the
Commission in Washington,  D.C. Copies of such material can be obtained from the
Public  Reference  Section of the Commission,  Washington,  D.C.,  20549, at the
Commission's New York Regional Office located at Seven World Trade Center, Suite
1300, New York, New York 10048,  and at its Midwest  Regional  Office,  500 West
Madison Street, Suite 1400, Chicago,  Illinois 60661.  Descriptions contained in
this Registration Statement as to the contents of any contract or other document
filed as an exhibit to this Registration  Statement are not necessarily complete
and each  such  description  is  qualified  by  reference  to such  contract  or
document.  The Commission maintains a Web site that contains reports,  proxy and
information  statements  and  other  information  regarding  issuers  that  file
electronically with the Commission (including the Company).  The address of this
Web site is http://www.sec.gov.

      The  Company  intends to furnish to its  stockholders,  after the close of
each fiscal year, an annual report relating to the operations of the Company and
containing  audited  financial  statements  examined  and  reported  upon  by an
independent certified public accountant. In addition, the Company may furnish to
stockholders such other reports as may be authorized,  from time to time, by the
Board of Directors. The Company's year end is December 31.


                                      9

<PAGE>



Item 2. Management's Discussion and Analysis or Plan of Operation

      ABS is a developmental  stage company.  As such, the financial  results of
operations  reflect  the  primary  activities  of the  Company  directed  toward
development and testing of its GPS products, principally for offender monitoring
in the criminal justice marketplace.

      The following table provides a breakdown of selected results of operations
for the three months  ended March 31, 1999,  and March 31, 1998 and is the basis
for the following discussion of first quarter results.

               Selected Results of Operations For the three months
                                     ended:
                                   (Unaudited)


                                                  March 31, 1999  March 31, 1998
                                                  --------------  --------------

Revenues .........................................   $  48,869  $      9,663
Cost of Sales ....................................      38,124        20,832
                                                    -----------   ------------
Gross Profit Loss) ...............................   $  10,745    ( $11,169 )

Expenses
     Research and Development ....................   $  33,184  $     58,026
     Sales and Marketing .........................     127,126        64,130
     General and Administrative ..................     523,761       397,232
                                                    -----------   ------------

      Total Expenses .............................   $ 684,071       519,388
                                                    -----------   ------------
      Loss from Operation ........................    (673,326)     (530,557)

Other Income and Expense)
     Interest Income .............................      - 0 -         - 0 -
     Other Income ................................      - 0 -         - 0 -
     Loss on Sales of Property and Equipment            - 0 -       (    349 )
     Interest Expense ............................    ( 53,906 )    (  7,774 )
     Asset Abandonment ...........................         - 0        - 0 -
                                                     -----------   ------------

      Provision for Income Taxes .................      - 0 -         - 0 -

       Net Loss ..................................   ( 727,232 )   ( $538,680 )
                                                       =======       ========

      (a)   Revenue

      The Company derives revenue from sale of products,  billable  services for
monitoring,  software license fees,  equipment and software leasing, and charges
for maintenance and repair of equipment.

                                      10

<PAGE>



For the quarter ended March 31, 1999, Revenue increased $39,206,  to $48,869, an
increase of 405.7% over the comparable period of 1998 of $9,963. The reasons for
this increase are higher monitoring service fees as a result of more units being
monitored by ABS,  and  additional  lease fees,  as a result of more units being
leased in the first  quarter of 1999 as  compared  to the  comparable  period in
1998. For the twelve months ended December 31, 1998, Revenue increased $23, 253,
or 89.1%,  over the comparable period of 1997. The reasons for this increase are
higher  monitoring  service fees as result of more units being monitored by ABS,
and  additional  lease fees,  as a result of more units being  leased in 1998 as
compared to the comparable period in 1997.

      (b)   Cost of Sales

      Cost of Sales  represents the direct costs  associated with the generation
of revenue, and includes cost of goods for products which are sold, direct costs
of  distribution  of software and equipment,  maintenance  expenses on equipment
repaired  under  service  agreements,  and the  direct  variable  communications
expenses  associated with the monitoring  services provided by the Company.  For
the three months ended March 31,  1999,  Cost of Sales was $38,124,  or 78.7% of
revenues,  compared with $20,832, or 215.6% of revenue for the comparable period
in 1998.  The  primary  reasons for the lower cost of sales as a  percentage  of
revenue in the 1999 period were  increased  utilization of the Company assets in
the field, resulting in higher revenue generation per unit and a lowering of the
fixed communications costs as a percentage of that revenue.

      For the twelve months ended December 31, 1998,  Cost of Sales was $90,146,
or 182.7% of  revenues,  compared  with  $22,867,  or 87.6% of  revenue  for the
comparable period in 1997. The primary reasons for the higher cost of sales as a
percentage  of  revenue  in 1998  were,  increased  cellular  and long  distance
telephone  expenses,  and  increased  shipping  and  delivery  expenses.   These
proportionate  increases  were due to an increase in the number of customer  and
prospect demonstrations and demonstration units deployed by the company in 1998,
as a result of its sales and marketing activities.

      (c)   Gross Profit

      For the first three months of 1999, Gross Profit for the Company increased
$21,914,  to $10,475,  compared to a negative  Gross  Profit of $(11,169) in the
comparable   period  of  1998.   The   reasons  for  this   increase   were  the
proportionately  lower Cost of Sales in the 1999 period,  as discussed above. In
the twelve months ended December 31, 1998, Gross Profit for the Company declined
$44,026,  to a loss of $40,793  compared to a positive Gross Profit of $3,233 in
the  comparable   period  of  1997.  The  reasons  for  this  decline  were  the
proportionately higher Cost of Sales in 1998, as discussed above.

      (d)   Expenses Research and Development

      Research and Development expenses are the direct costs associated with the
Company's  development of its  proprietary  products.  Expenses in this category
include the cost of outside contracted engineering and design, staffing expenses
for the Company's own engineers and software

                                      11

<PAGE>



developers,  and  the  actual  costs  of  components,  prototypes,  and  testing
equipment and services used in the product development functions.  For the first
three months of 1999,  Research and Development  expenses  decreased  $24,842 to
$33,184,  compared  to $58,026 in the  comparable  period of 1998.  The  primary
reason for this decrease was the timing for the  continuing  development  of the
Company's ABS COMTRAK unit for criminal justice  temporarily reduced expenses in
this  category.  The Company  was in the  planning  stages for its next  product
release,  and  therefor  was not  expending  as much with its outside  suppliers
during the period.

      Research and Development  expenses  increased $217,199 in the twelve month
period  ending  December  31,  1998 to  $500,628,  compared  to  $283,429 in the
comparable  period of 1997. The primary reason for this increase was the funding
for the  continuing  development  of the Company's ABS COMTRAK unit for criminal
justice  applications  and for  development of the Company's  monitoring  center
system.  The new device was  installed in 1998 for  customers  and  prospects in
Arizona, Texas, Iowa, Wisconsin, New Jersey, and Ohio.

      (e)   Sales and Marketing

      Sales and Marketing  expenses  represent the costs of the Company's  sales
and marketing staff,  travel and related  expenses  associated with sales to the
Company's  customers and  prospects,  the costs of  advertising in magazines and
periodicals,  attendance at trade shows, and production of marketing and related
collateral  material.  For the three  months  ended  March 31,  1999,  Sales and
Marketing  expenses  increased  $62,996 to $127,126,  compared to $64,130 in the
comparable  quarter of 1998.  The primary  reason for this increase was that the
Company  increased the sales & marketing  staff and payroll over the  comparable
period in 1998.

      Sales and Marketing  expenses  increased $43,068 to $427,120 in the twelve
months ended December 31, 1998, compared to $384,052 in the comparable period of
1997. The reason for this increase was the Company's  expanded efforts to market
the ABS COMTRAK unit to the criminal  justice market place in 1998, and to build
a market image for that product within the criminal justice market.

      (f)   General and Administrative

      General and  Administrative  expenses  are all the  indirect  and overhead
expenses  associated  with  the  operations  of the  Company,  outside  of those
expenses described above. These expenses include executive,  administrative, and
accounting staff payroll,  taxes and benefits,  rent on property, all travel not
included in the Sales and Marketing expense,  fixed telephone  expenses,  office
leases and supplies,  and recruiting and training expense.  For the three months
ended March 31, 1999, General and  Administrative  expense increased $126,529 to
$523,761,  from $397,232 in the comparable  period of 1998. The primary  reasons
for this  increase were  increases in  administrative  and  executive  staff and
payroll.


                                      12

<PAGE>



      For the twelve months ended December 31, 1998,  General and Administrative
expense  increased by $628,000 to $2,176,396,  from $1,548,396 in the comparable
period  of 1997.  The  primary  reasons  for this  increase  were  increases  in
administrative and executive staff and payroll.

      (g)   Profit (loss) from Operations

      For the three months ended March 31, 1999, Loss from Operations  increased
$142,769 to $(673,326),  compared to $(530,557) for the same period in 1998. The
reason for this increase was higher expenses in the period,  as explained above,
offset by slightly higher gross profits.

      For the twelve  months  ended  December  31,  1998,  Loss from  Operations
increased  by  $(932,293)  to  $(3,144,937),  compared to an  operating  loss of
$(2,212,644)  in the  comparable  period of 1997.  The reasons for this increase
were higher Research and Development and General and Administrative expense, and
to a lesser extent, higher Sales and Marketing expense, and lower Gross Profit.

      (h)   Interest Expense

      For the three  months  ended March 31, 1999,  Interest  expense  increased
$46,132 to $53,906,  compared to  Interest  expense of $7,774 in the  comparable
period of 1998.  This interest  expense  increase was due to larger  outstanding
balances in Company borrowings in 1999 over 1997.

      For the twelve months ended December 31, 1998,  Interest expense increased
$22,614 to $206,426,  compared to Interest expense of $183,812 in the comparable
period of 1997.  This  interest  expense  increase  was due  primarily to larger
outstanding balances in Company borrowings in 1998 over 1997.

      (i)   Asset Abandonment Charge

      For the twelve  months ended  December 31,  1998,  the Company  incurred a
charge  for  Asset  Abandonment  of  $94,300..  This  charge  was the  result of
adjustments to the Company's  property and equipment  assets to reflect obsolete
or unusable assets.

      (j)   Net Loss

      For the three months  ended March 31, 1999,  the Company had a Net Loss of
$(727,232)  or $(.06) per share,  compared to a Net Loss of  $(538,680),  in the
comparable period of 1998, for the reasons described above.

      For the twelve months ended  December 31, 1998, the Company had a Net Loss
of $(3,446,012) or $(.37) per share, compared to a Net Loss of $(1,825,259),  or
$(.33) per share in the  comparable  period of 1997,  for the reasons  described
above.


                                      13

<PAGE>



      (k)   Liquidity and Capital Resources

      For the three months ended March 31, 1999,  the Company used  $(1,111,408)
of cash in operating  activities and another $(43,909) in investing  activities.
It generated $(689,782 in cash from financing activities.  The total of all cash
flow  activities  resulted  in a  decrease  in the  balance  of  cash  and  cash
equivalents for the three month period of $(365,535).

      For  the  twelve  months  ended   December  31,  1998,  the  Company  used
$(2,863,876) of cash in operating activities and another $(358,581) in investing
activities. It generated $3,599,749 in cash from financing activities. The total
of all cash flow  activities  resulted in an increase in the balance of cash and
cash  equivalents  of  $377,292  for the 1998 fiscal  year.  This  increase  was
primarily  the result of an increase in cash  provided by financing  activities,
and reduced by the increase in cash used in operating and investing activities.

      As noted in the accompanying Independent Auditors Report, the Company is a
development stage business and has not yet achieved profitable  operations.  The
Company  lacks  sufficient  operating  capital,  and intends to fund its ongoing
development  and operations  through a combination of additional  equity capital
and  further  borrowings.  As of  March  31,  1999,  the  Company  did not  have
commitments  for  either  debt or share  purchases  to a meet its  planned  1999
operating capital requirements.

      (l)   Impact of Year 2000 Issues

      The Year 2000 issue is related to computer  software  utilizing two digits
rather  than four to  define  the  appropriate  year.  As a  result,  any of the
Company's  computer  programs or any of the Company's  suppliers or vendors that
have date  sensitive  software may incur system  failures or generate  incorrect
data if "00" is recognized as 1900 rather than 2000.

      The Company has been  addressing Year 2000 issues  throughout  fiscal year
1998 and has modified or is in the process of modifying any products or services
that are  affected by Year 2000 issues.  The Company has a formal  comprehensive
Year  2000  readiness  plan in  place  and  under  the  oversight  of  executive
management.

      The Company's greatest risk for a material  disruption in services lies in
a  potential  disruption  of  telecommunication  services  due  to  an  external
telecommunication  service  provider's failure to be Year 2000 compliant and the
resulting  impact  upon the  Company's  monitoring  services.  The  Company  has
contacted and obtained  assurances  from its  telecommunications  providers that
their  networks are Year 2000  compliant.  In  addition,  the Company has backup
telecommunication  provider  connectivity  if for any reason the primary carrier
has a disruption in service.

      Databases,  operating  systems and system  hardware have been reviewed and
updated as necessary for Year 2000 readiness. A review of the model 1702 GPS PTU
date format  revealed  that the 4-digit year is being used for all  calculations
and Year 2000 issues should affect the model 1702.

                                      14

<PAGE>



Year 2000 issues were known when the GPS control software was developed and code
was written to comply with these issues.

      Reviews of models 100, 101 and 102  firmware of our HA products  show that
they are not  affected  by Year 2000  issues due to the way the  information  is
processed.  The internal hardware  components have been reviewed and will not be
affected by Year 2000 issues.  Review is currently  being done on the HA control
software that reports violations.

      In addition to the review of the system,  a Year 2000  testing  laboratory
was  also  established.   In  this  laboratory,  a  monitoring  environment  was
established  that  mirrored the current  operating  environment.  As part of our
testing,  all monitoring computers and monitoring units were set to December 31,
1999 and allowed to run for three (3) days.  Preliminary  results show continued
unaffected processing of monitoring information.

      The Company  believes that, based upon changes and  modifications  already
made and those that are  currently  planned  for  implementation  in fiscal year
1999,  the impact of Year 2000  issues  will not be  material.  However,  to the
extent  the  Company or third  parties on which it relies do not timely  achieve
Year 2000  readiness,  the  Company's  results of  operations  may be  adversely
affected.

Item 3. Description of Property

            The Company leases  approximately  6,212 square feet of office space
located  at  3345  No.  107th  Street,  Omaha,  Nebraska.  All of the  Company's
administrative,  sales,  service and other business  operations are conducted at
this  location.  This lease is for a term  commencing  on December 1, 1998,  and
ending on November 30, 2001.  The base rent is  $4,659.00  per month.  The lease
also  requires the Company to pay  $1,099.53  per month as its pro rata share of
the operating expenses respecting the leased premises.

            The Company leases  computers,  office  equipment and furniture from
several sources. The rent for such items is in excess of $3,900.00 per month.

            In the opinion of the Company's management, the Company's properties
are adequately covered by insurance.

Item 4. Security Ownership of Certain Beneficial Owners and Management

      The following table sets forth certain  information  regarding  beneficial
ownership of the Company's common stock, par value $0.001 per share (the "Common
Shares"), as of May 27, 1999, by (i) each stockholder known by the Company to be
a beneficial owner1 of more than five percent
- --------
1A beneficial owner of a security means

      (a)  Any  person  who,  directly  or  indirectly,  through  any  contract,
      arrangement,  understanding,  relationship or otherwise has or shares: (1)
      voting  power,  which  includes the power to vote, or to direct the voting
      of, such security or (2)  investment  power,  which  includes the power to
      dispose, or to direct the disposition of, such security.

      (b) Any  person  who,  directly  or  indirectly,  creates or uses a trust,
      proxy,  power of attorney,  pooling  arrangement,  or any other  contract,
      arrangement  or device with the purpose or effect of divesting such person
      of beneficial  ownership of a security or  preventing  the vesting of such
      beneficial ownership.

                                      15

<PAGE>



of the Common  Shares,  (ii) by each of the  Company's  directors  and executive
officers,  and (iii) the  directors and  executive  officers as a group.  Unless
otherwise  indicated,  all shares are owned directly and the indicated owner has
sole voting and dispositive power with respect thereto.



   Name and Address of         Amount and Nature of
     Beneficial Owner           Beneficial Owner            Percent of Class
     ----------------           ----------------            ----------------

Dennis Anderson                     1,017,114                     8.31%
135 Lois Avenue
Carroll, Iowa 51401

Robert Badding                       773,843                      6.32%
304 Timberline Road
Carroll, Iowa 51401

John Gaukel                          510,000                      4.17%
3854 No. 208th Street
Elkhorn, Nebraska 68022

Roger Kanne2                         702,126                      5.74%
1311 Amy Avenue
Carroll, Iowa 51401

Benjamin J. Lamb                    1,000,000                     8.17%
11205 Washington Street
Omaha, Nebraska 68137

Ronald Muhlbauer                     705,286                      5.76%
222 Pleasant Ridge
Carroll, Iowa 51401

James Pietig                         372,574                      3.04%
129 Pleasant Ridge
Carroll, Iowa 51401

Rob Rasmussen                        282,600                      2.31%
13912 Poppleton Circle
Omaha, Nebraska 68144

- --------
2Includes 592,626 Common Shares held directly by Mr. Kanne, 29,358 Common Shares
held by Country  Stores,  50,729  Common  Shares held by E. T. Videos and 29,413
Common Shares held by K & K Developers.  Country,  Stores, E.T. Videos and K & K
Developers are affiliates of Mr. Kanne.

            16

<PAGE>





Directors and Executive             5,363,543                     43.82%
Officers as a Group (8
persons)

 .

Item 5. Directors, Executive Officers, Promoters and Control Persons

      The  executive  officers and directors of the Company and their ages as of
the date of this Registration Statement are as follows:



Name                               Age                 Position
- ----                               ---                 --------

Benjamin J. Lamb                    57    President and Chief Executive Officer,
                                                                        Director

Rob Rasmussen                       58                       Secretary, Director

John Gaukel                         54                  Vice President, Director

Roger Kanne                         58                       Treasurer, Director

Dennis Anderson                     54                                  Director

Robert Badding                      69                                  Director

Ronald Muhlbauer                    57                                  Director

James Pietig                        56                                  Director


Benjamin "Jack" Lamb was elected  President and Chief  Executive  Officer of ABS
effective February 1, 1999, and was elected to the Board of Directors.  He has a
proven track record for taking  programs from concept to business plan,  funding
through  development,  into test and on to production and sales in  rapid-growth
technology  markets.  Mr. Lamb is a graduate of the University of Georgia with a
BA degree in  Psychology  and he holds an AS Degree in General  Science from the
U.S. Army Institute of Technology.  He has over 30 years experience in executive
management positions,  most notably with Harris Corporation.  More recently, Mr.
Lamb was founder and Chief Executive Officer of INTECK Corporation,  a privately
held software company.

     Rob  Rasmussen is Secretary and has been a member of the Board of Directors
of since May, 1997. He has over 30 years of experience as an administrator  with
service-oriented  companies,  including 15 years with Arthur  Andersen & Co., an
internationally known CPA firm. Mr. Rasmussen is a graduate of the University of
Denver,  Colorado,  with a BS  degree  in  Business  Administration  and he is a
Certified Public  Accountant.  He was responsible for the preliminary review and
due  diligence  of ABS leading to the  acquisition  of  majority  control of the
Company. Mr. Rasmussen served as Chief Operating Officer from acquisition of the
Company until February, 1999. In that capacity, he had day-to-day responsibility
for the operation of ABS and stabilizing the Company's relationships with

                                      17

<PAGE>



shareholders,  banks,  suppliers and  creditors.  Mr.  Rasmussen's  present
responsibilities include Business Development and Investor Relations.

John Gaukel is Vice President and Chief Technical  Officer and has been a member
of the Board of  Directors  since 1995.  He is a graduate of the  University  of
Nebraska at Omaha,  with a BS degree in Physics and a minor in Mathematics.  Mr.
Gaukel is the inventor of the patent  pending  technology of ABS, which has been
assigned to the Company, and he holds three other patents which are unrelated to
ABS's business. He continues to devote his time to the ever-evolving changes and
enhancements to the Company's product lines.

Ronald W.  Muhlbauer is Chairman of the Board and has been a member of the Board
of Directors since 1996. He is a Certified  Public  Accountant and, for the past
27 years, has been a partner with the accounting firm of Olsen, Muhlbauer & Co.,
L.L.P., in Carroll, Iowa. Mr. Muhlbauer is a graduate of Creighton University in
Omaha, Nebraska, with a BS degree in Business Administration.

Roger J. Kanne has been  Treasurer and a member of the Board of Directors of ABS
since October, 1997. His business experience stems from his involvement as owner
and  operator  of several  business  entities  including  retail  and  wholesale
petroleum jobbers, real estate developments, convenience stores and video stores
in an eight state area.

Dennis L. Anderson joined the Board of Directors of ABS in October,  1997. He is
a  graduate  of  Buena  Vista   University  of  Iowa  and  currently  serves  as
secretary-treasurer  of The Farner Bocken  Company of Carroll,  Iowa, a regional
distributor  of food,  tobacco and related  snack  products  to  locations  in a
multi-state area. Mr. Anderson has been active in the management of this closely
held corporation for the past 24 years.

Robert E. Badding  joined the Board of Directors of ABS in October,  1997. He is
founder  and  Chief  Executive  Officer  of  Badding  Construction,  a  regional
commercial and residential  construction  firm. Mr. Badding has been involved in
all levels of the construction management of this multi-state firm.

     James L. Pietig joined the ABS Board in December,  1997.  Mr. Pietig served
as Chief Executive officer of Pepsi Cola Company of Carroll,  Iowa. He currently
manages his investments in a hotel- convention complex and in private and public
land companies and developments.

      The Company's  certificate  of  incorporation  provides that the Company's
Board of Directors is to be divided into three classes. As a result of the Share
Exchange, however, all directorships will be open to election at the next annual
meeting of the  stockholders.  It is anticipated that at the next annual meeting
of stockholders such  directorships  will be divided into three classes with one
class  having a term of one year,  one class  having a term of two years and one
class  having a term of three  years.  At each  annual  meeting of  stockholders
thereafter  at which  the term of each  class of  directors  expires,  successor
directors of such class will be elected for a three-year term.


                                      18

<PAGE>



      Executive  officers of the Company are appointed by the Board of Directors
on an annual basis and serve until their  successors  have been duly elected and
qualified.

      The Board of  Directors is expected to establish  and  designate  specific
functions and areas of oversight to an Executive  Committee,  an Audit Committee
and a Compensation Committee on or before October 1, 1999. The Bylaws permit the
creation of additional committees.

Item 6. Executive Compensation

            The Company's chief executive  officer receives a base salary in the
amount of $150,000 per year.  In addition,  as a condition  of  employment,  the
chief executive officer received 1,000,000 Common Shares and options to purchase
4,000,000 Common Shares at an exercise price of $0.10 per share. The options are
exercisable and vested as follows:  (1) one-third of such options are vested and
exercisable  beginning the earlier of December 30, 1999, or when the closing bid
price  for  the  Common  Shares  exceeds  $3.00  per  share  for at  least  five
consecutive  trading  days;  (2)  one-third  of  such  options  are  vested  and
exercisable  beginning the earlier of December 30, 2000, or when the closing bid
price for the Common Shares exceeds $4.00 for at least five consecutive  trading
days; and (3) one-third of such options are vested and exercisable beginning the
earlier of  December  30,  2001,  or when the  closing  bid price for the Common
Shares exceeds $6.00 per share for at least five consecutive  trading days. When
vested,  the options are  exercisable  for a period of three years.  All options
shall vest and be  immediately  exercisable  in the event of a sale or merger of
the  Company,  including a transfer of control.  The chief  executive  officer's
employment  by the Company  commenced  on February  1, 1999 and,  therefore,  he
received no compensation  from the Company prior to that time. No other employee
of the Company received a salary and other  compensation  that exceeded $100,000
in any  year  preceding  the  date  hereof.  There  were  no  options  or  stock
appreciation rights outstanding during 1998.

Item 7. Certain Relationships and Related Transactions

      On April 6 and 8, 1998,  the Company  entered  into loan  agreements  with
Commercial   Savings  Bank  and  US  Bank,  each  in  the  principal  amount  of
$1,000,0000.  These loans were  unconditionally  guarantied by Dennis  Anderson,
Robert Badding, Mary Collison,  John Gaukel, Martin Halibur, Roger Kanne, Ronald
Muhlbauer,  James Pietig, Rob Rasmussen and James DiPrima.  In consideration for
giving these guaranties,  each of these individuals received 100,000 fully paid,
nonassessable Common Shares.

      James Pietig, a director of the Company,  and Mary Collison, a stockholder
of the Company, each established a line of credit in the amount of $500,000 with
First Star Bank of Iowa,  N.A.  (the  "lending  institution").  These loans were
unconditionally  guarantied by Dennis Anderson,  Robert Badding and Roger Kanne,
each of  whom is an  officer  and/or  director  of the  Company,  and by  Martin
Halibur,  a  stockholder  of the  Company.  The amounts  drawn on these lines of
credit bear interest at the lending institution's prime interest rate plus 0.250
percent (the "Regular Rate").  Interest is payable monthly. The entire amount of
unpaid principal and accrued interest is due and payable on January 31, 2000. On
April 30, 1999, the amounts drawn under these lines of credit were loaned by

                                      19

<PAGE>



Mr. Pietig and Ms. Collison to the Company.  As of the date of this registration
statement,  the  outstanding  principal  balance  under these lines of credit is
$1,000,000.  The Company has agreed to repay the loans under  substantially  the
same terms as with the lending  institution.  In the event of default,  however,
the Company  will pay  interest  at a rate equal to the  Regular  Rate plus five
percent (5%). These loans are unsecured. As consideration for entering into this
arrangement,  each of the lenders and  guarantors  received  83,333  fully paid,
nonassessable Common Shares and a warrant to purchase 83,333 Common Shares at an
exercise price of $1.00 per share,  exercisable at any time on or before October
31, 2000.

Item 8. Description of Securities

      (a)   General

      The authorized  capital stock of the Company consists of 50,000,000 Common
Shares,  and 1,000,000 shares of Preferred Stock, par value $0.01 per share (the
"Preferred Stock"). As of May 27, 1999, there were outstanding 12,238,572 Common
Shares held of record by 424 stockholders.
There are no shares of Preferred Stock presently outstanding.

      (b)   Common Shares

      Holders of Common Shares are entitled to one vote per share in all matters
to be  voted  on by  the  stockholders.  Subject  to  preferences  that  may  be
applicable to any Preferred  Stock  outstanding  at the time,  holders of Common
Shares are  entitled  to  receive  ratably  such  dividends,  if any,  as may be
declared  from  time to time by the  Board of  Directors  out of  funds  legally
available  therefor.  See  "Dividend  Policy".  In the  event of a  liquidation,
dissolution or winding up of the Company,  holders of Common Shares are entitled
to  share  ratably  in all  assets  remaining  after  payment  of the  Company's
liabilities and the liquidation preference, if any, of any outstanding Preferred
Stock.  All of the  outstanding  shares of  Common  Shares  are  fully  paid and
non-assessable.  The rights,  preferences  and  privileges  of holders of Common
Shares are  subject  to,  and may be  adversely  affected  by, the rights of the
holders  of shares of any  series  of  Preferred  Stock  which the  Company  may
designate and issue in the future.

      (c)   Preferred Stock

      The Board of  Directors  has the  authority,  without any further  vote or
action by the  stockholders,  to provide  for the  issuance  of up to  1,000,000
shares of  Preferred  Stock  from time to time in one or more  series  with such
designations,  rights, preferences and limitations as the Board of Directors may
determine, including the consideration received therefor. The Board also has the
authority to determine  the number of shares  comprising  each series,  dividend
rates, redemption provisions,  liquidation preferences, sinking fund provisions,
conversion  rights and voting rights  without  approval by the holders of Common
Shares.  Although it is not  possible  to state the effect that any  issuance of
Preferred  Stock  might  have on the rights of  holders  of Common  Shares,  the
issuance of Preferred Stock may have one or more of the following effects (i) to
restrict  Common Shares  dividends if Preferred  Stock  dividends  have not been
paid, (ii) to dilute the voting power and equity

                                      20

<PAGE>



interest  of holders of Common  Shares to the extent  that any  Preferred  Stock
series  has  voting  rights or is  convertible  into  Common  Shares or (iii) to
prevent  current  holders of Common Shares from  participating  in the Company's
assets upon liquidation until any liquidation  preferences granted to holders of
Preferred Stock are satisfied. In addition, the issuance of Preferred Stock may,
under certain circumstances, have the effect of discouraging a change in control
of the Company by, for example,  granting  voting rights to holders of Preferred
Stock that  require  approval by the  separate  vote of the holders of Preferred
Stock  for  any  amendment  to  the   Certificate   of   Incorporation   or  any
reorganization, consolidation, merger or other similar transaction involving the
Company.  As a result,  the issuance of such Preferred Stock may discourage bids
for the Common  Shares at a premium  over the market price  therefor,  and could
have a materially  adverse effect on the market value of the Common Shares.  The
Board of Directors  does not  presently  intend to issue any shares of Preferred
Stock.

      (d)   No Preemptive Rights

      No holder of any capital stock of the Company has any preemptive  right to
subscribe for or purchase  securities  of any class or kind of the Company,  nor
any redemption or conversion rights.

      (e)   Delaware Business Combination Statute

      The  Company  will be subject  to the  provisions  of  Section  203 of the
Delaware General Corporation Law (the "DGCL"). In general,  this law prohibits a
publicly held  Delaware  corporation  from engaging in a "business  combination"
with an "interested stockholder" for a period of three years after the date that
the person became an interested stockholder unless (with certain exceptions) the
business combination or the transaction in which the person became an interested
stockholder  is  approved  in  a  prescribed  manner.   Generally,  a  "business
combination"  includes  a  merger,  asset or stock  sale,  or other  transaction
resulting in a financial benefit to the stockholder. An "interested stockholder"
is, generally  defined as a person who, together with affiliates and associates,
owns (or within  three years  prior,  did own) 15% or more of the  corporation's
voting  stock.  This  provision of Delaware law may have the effect of delaying,
deferring  or  preventing  a change of control of the  Company  without  further
action by the stockholder.

      (f)   Certain Charter Provisions

            (i)   General

            Certain provisions of the Company's Certificate of Incorporation and
Bylaws could make more  difficult the  acquisition  of the Company by means of a
tender  offer,  a proxy contest or otherwise as well as the removal of incumbent
officers and  directors.  These  provisions  are expected to discourage  certain
types  of  coercive  takeover  practices  and  inadequate  takeover  bids and to
encourage  persons  seeking to acquire control of the Company to first negotiate
with the Company.


                                      21

<PAGE>



            (ii)  Number of Directors; Removal; Vacancies

            The  Certificate  of  Incorporation  and the Bylaws provide that the
number of directors shall be determined from time to time  exclusively by a vote
of a majority of the  Company's  Board of  Directors  then in office;  provided,
however,  that the number of Directors shall not be less than three (3) nor more
than fifteen  (15).  The  Certificate  of  Incorporation  also provides that the
Company's  Board of Directors  shall have the exclusive right to fill vacancies,
including  vacancies  created by an expansion of the Board.  The  Certificate of
Incorporation  further  provides  that  Directors may be removed with or without
cause upon the affirmative  vote of at least  two-thirds of all of the shares of
the Company's  capital stock then entitled to vote in the election of directors;
provided,  however,  that if there are one or more Interested  Stockholders  (as
defined in Article 9 of the  Certificate  of  Incorporation),  Directors  may be
removed only for cause and, in addition to such two-thirds vote, there must also
be an  affirmative  vote for  removal of not less than a majority  of the voting
power  of  the  shares  held  by   stockholders   other  than  such   Interested
Stockholders.

            (iii) Classified Board of Directors

            The Certificate of Incorporation provides for the Company's Board of
Directors  to be divided  into  three  classes of  directors  serving  staggered
three-year terms. As a result, approximately one-third of the Company's Board of
Directors  will be elected each year.  See  "Management--Executive  Officers and
Directors".  This  provision  could  prevent a party who  acquires  control of a
majority of the outstanding  voting stock from obtaining control of the Board of
Directors until the second annual  stockholders  meeting  following the date the
acquiror  obtains the controlling  stock  interest.  It could have the effect of
discouraging  a  potential  acquiror  from  making a tender  offer or  otherwise
attempting to obtain control of the Company, thus increasing the likelihood that
incumbent directors will retain their position.

            (iv)  Approval of Repurchases

            The  Certificate  of  Incorporation  prohibits  repurchases  by  the
Company  from  a  stockholder  owning  more  than  5% of  the  Company's  voting
securities  (a  "Significant   Stockholder")   (other  than  those  stockholders
currently meeting such description) who has owned such securities of the Company
for less than two years,  unless  approved by an affirmative  vote of at least a
majority  of the total  votes  entitled  to vote  generally  in the  election of
Directors other than the voting power held by the Significant Stockholder.

            (v)   Amendments to Bylaws

            The  Certificate  of  Incorporation   provides  that  the  Board  of
Directors or the holders of at least  two-thirds  of all shares of the Company's
capital  stock  then  entitled  to vote have the  power to amend or  repeal  the
Company's Bylaws;  provided,  however,  that if there are one or more Interested
Stockholders,  the Bylaws may be amended,  in addition to such two-thirds  vote,
upon the  affirmative  vote for such  action of not less than a majority  of the
voting  power of the shares  held by  stockholders  other  than such  Interested
Stockholders.

                                      22

<PAGE>




            (vi)  Amendment of the Certificate of Incorporation

            Any proposal to amend,  alter, change or repeal any provision of the
Certificate of  Incorporation  requires  approval by the  affirmative  vote of a
majority vote of the voting power of all of the shares of the Company's  capital
stock  entitled  to vote  generally  in the  election  of  directors;  provided,
however,  that an affirmative  vote of the holders of at least two-thirds of the
total votes  eligible to be case is required to amend the  provisions  described
above.

      (g)   Limitation of Liability and Indemnification

      The Certificate of  Incorporation  contains certain  provisions  permitted
under  the  DGCL  relating  to the  liability  of  directors.  These  provisions
eliminate a director's  personal liability for monetary damages resulting from a
breach of fiduciary  duty,  except in certain  circumstances  involving  certain
wrongful  acts,  such as a breach of a  director's  duty of  loyalty  or acts or
omissions  that involve  intentional  misconduct or a knowing  violation of law.
These  provisions  do not limit or  eliminate  the rights of the  Company or any
stockholder to seek non-monetary relief, such as an injunction or rescission, in
the event of a breach of a director's  fiduciary duty. These provisions will not
alter a director's  liability under federal  securities laws. The Certificate of
Incorporation and Bylaws also contain provisions  indemnifying the directors and
officers of the Company to the fullest extent permitted by the DGCL. The Company
believes  that these  provisions  will  assist the  Company  in  attracting  and
retaining qualified individuals to serve as directors.

      (h)   Transfer Agent and Registrar

      The  Transfer  Agent and  Registrar  of the Common  Shares is Atlas  Stock
Transfer Corporation of Salt Lake City, Utah.


                                      23

<PAGE>



                                   PART II.

Item 1 Market Price of and  Dividends on the  Company's  Common Equity and Other
     Shareholder Matters

      The Common  Shares of the  Company  are traded on the OTC  Bulletin  Board
under the trading  symbol ABSH (or ABSHE).  The  following  table sets forth the
high and low bid information for each quarter since January, 1998.


        Year                Quarter                High                  Low
        ----                -------                ----                  ---

        1998                  1st                $2.6250               $1.2500

                              2nd                $4.3750               $1.2500

                              3rd                $4.5000               $1.5000

                              4th                $2.6875               $0.7500

        1999                  1st                $2.1250               $0.7500


The source of the foregoing  information is Bloomberg,  L.P.  Quotations reflect
inter-dealer prices, without retail mark-up, mark-down or commission and may not
represent actual transactions.

      Prior to January,  1998,  the Common  Shares were traded  under the symbol
SAII; however,  the Company does not have any bid information prior to the Share
Exchange.

      As of May 27, 1999, there were outstanding  12,238,572  Common Shares held
of record by 424 stockholders.  There are no shares of Preferred Stock presently
outstanding.

Item 2. Legal Proceedings

      The  Company's  subsidiary,  ABS  Nebraska,  is a  defendant  in an action
pending  in  Montana  Eighteenth  Judicial  District  Court,   Gallatin  County,
captioned Applied  Technologies,  Inc. v. Advanced Business  Sciences,  Inc., et
al., No.  98-285.  This action was initially  filed on September  11, 1998.  The
Amended Complaint alleges that ABS Nebraska is in breach of contract under which
the  Plaintiff,  Applied  Technologies,  Inc.,  was  to  produce  prototype  and
production  parolee tracking devices.  The Amended Complaint seeks  compensatory
and  consequential  damages in an amount to be determined  at trial,  attorney's
fees and such  other  relief as the court may deem  equitable  and  proper.  ABS
Nebraska has denied the allegations, has raised certain affirmative defenses and
has brought a  counterclaim  alleging,  among other  things,  that the Plaintiff
failed  to  deliver  in  a  timely  manner  all  documents  schematic  drawings,
mechanical drawings,  computer disks of designs, vendors lists with part numbers
and art work.  Management  believes  that,  in the event of an adverse  decision
against ABS Nebraska, the maximum liability will not exceed $90,000.


                                     II-1

<PAGE>



Item 3. Changes in and Disagreements with Accountants

                               [Not applicable]

Item 4. Recent Sales of Unregistered Securities

      On December  17, 1997,  the Company  consummated  a plan and  agreement of
reorganization  with ABS  Nebraska and all of the  shareholders  of ABS Nebraska
(the "ABS  Shareholders").  Under this agreement,  the Company issued  7,050,000
Common  Shares to the ABS  Shareholders  in  exchange  for all of the issued and
outstanding  shares of ABS Nebraska.  An additional  450,000  Common Shares were
issued to  finders.  Certain  ABS  Shareholders  were also  issued  warrants  to
purchase  574,000 Common Shares at an exercise  price of $1.00 per share,  which
warrants expire on December 20, 2000. As a result of this  transaction,  the ABS
Shareholders  owned  approximately 88% of the then issued and outstanding Common
Shares and ABS Nebraska became the wholly-owned  subsidiary of the Company. This
transaction   was  exempt  from  the   registration   and  prospectus   delivery
requirements of the Securities Act of 1933, as amended (the  "Securities  Act"),
under Section 4(2) thereof.

      Effective [December 31, 1997], the Company issued 165,000 Common Shares as
payment for certain accounts payable, 82,500 Common Shares for certain services,
and 2,063 Common Shares as payment of bonus compensation to an employee. Each of
these  transactions  was exempt from the  registration  and prospectus  delivery
requirements of the Securities Act under Section 4(2) thereof.

      On  February  1,  1998,  the  Company  issued  1,250,000  units  having an
aggregate purchase price of $2,500,000. A unit consisted on one Common Share and
a warrant to purchase  one Common  Share at an  exercise  price of (1) $3.00 per
share during the first year,  (2) $4.00 per share during the second year and (3)
$5.00 per share during the third year. The warrants expire February 1, 2001. All
but sixteen investors in this offering were accredited investors.  The Company's
management  believes that this  transaction  was in substantial  compliance with
Rule 506 under  the  Securities  Act;  however,  the  Company  has a  contingent
liability  for the  entire  offering  plus  costs  associated  with  any  future
litigation respecting this matter.

      Effective  April 1, 1998, the Company issued  1,000,000  shares to certain
individuals in consideration  for these individuals  giving their  unconditional
guaranty of indebtedness  incurred by the Company with  Commercial  Savings Bank
and  US  Bank.  See  "Certain  Relationships  and  Related  Transactions."  This
transaction   was  exempt  from  the   registration   and  prospectus   delivery
requirements of the Securities Act under Section 4(2) thereof.

      On August 24, 1998, the Company issued  2,191,145 Common Shares to acquire
Comguard Leasing and Financial, Inc., an Illinois corporation.  This transaction
was rescinded  effective June 1, 1999.  However,  242,500 Common Shares remained
outstanding as consideration for services in consummating the transaction.  This
transaction   was  exempt  from  the   registration   and  prospectus   delivery
requirements of the Securities Act under Section 4(2) thereof.


                                     II-2

<PAGE>



      In 1999, the Company issued 152,000 Common Shares as payment of bonuses to
employees  accrued during 1998. Each of these  transactions  was exempt from the
registration  and prospectus  delivery  requirements of the Securities Act under
Section 4(2) thereof.

      On February 1, 1999, the Company agreed to issue  1,000,000  shares of its
Common Shares to Benjamin J. Lamb in consideration for Mr. Lamb entering into an
employment  agreement  with the Company.  This  transaction  was exempt from the
registration  and prospectus  delivery  requirements of the Securities Act under
Section 4(2) thereof.

      On March 15, 1999, the Company issued to certain  directors,  officers and
stockholders of the Company in the aggregate  500,000 Common Shares and warrants
to purchase in the aggregate 500,000 Common Shares at an exercise price of $1.00
per share.  The warrants are  exercisable  at any time on or before  October 31,
2000.  These  securities  were given in  consideration  for direct  loans to the
Company or for giving unconditional  guaranties to loans from First Star Bank of
Iowa, N.A. which funded this indebtedness.  This transaction was exempt from the
registration  and prospectus  delivery  requirements of the Securities Act under
Section 4(2) thereof.

      On June 1, 1999,  the  Company  entered  into  agreements  rescinding  the
Comguard  Acquisition.  To consummate  this  rescission,  the Company  issued to
Frederick Bishop 100,000 Common Shares and issued to Michael Reeves a warrant to
purchase 50,000 Common Shares at an exercise price of $1.50 per share,  expiring
on June  1,  2004.  This  transaction  was  exempt  from  the  registration  and
prospectus  delivery  requirements  of the  Securities  Act under  Section  4(2)
thereof.

Item 5. Indemnification of Directors and Officers

      Section  145 of the  General  Corporation  Law of the  State  of  Delaware
permits  indemnification  by  a  corporation  of  certain  officers,  directors,
employees and agents. Consistent therewith, Article 12 of the Company's Restated
Certificate of  Incorporation  provides that the Company,  to the fullest extent
permitted by law, shall indemnify a director,  officer, employee or agent of the
Company or a person  who is or was  serving  at the  request  of the  Company as
director, officer, employee or agent of another corporation,  partnership, joint
venture, trust or other enterprise.

      Article  VIII  of  the  Company's   Restated   Bylaws  provides  that  any
indemnification (unless ordered by a court) shall be made by the Company only as
authorized in the specific case upon a determination that indemnification of the
director or officer is proper in the  circumstances  because such person has met
the applicable standard of conduct, as the case may be. Such determination shall
be made,  with  respect to a person who is a director  or officer at the time of
such determination,  (i) by a majority vote of the directors who are not parties
to such action, suit or proceeding, even though less than a quorum, or (ii) by a
committee of such  directors  designated by a majority  vote of such  directors,
even though less than a quorum,  or (iii) if there are no such directors,  or if
such directors so direct,  by independent  legal counsel in a written opinion or
(iv) by the  stockholders.  Such  determination  shall be made,  with respect to
former directors and officers,  by any person or persons having the authority to
act on the  matter on behalf of the  Company.  To the  extent,  however,  that a
present or former  director or officer of the Company has been successful on the
merits or otherwise

                                     II-3

<PAGE>



in defense of any action,  suit or proceeding  described above, or in defense of
any claim,  issue or matter  therein,  such person shall be indemnified  against
expenses  (including  attorneys' fees) actually and reasonably  incurred by such
person in connection  therewith,  without the necessity of  authorization in the
specific case.  including  service with respect to an employee benefit plan, who
was or is  made  (or  threatened  to be  made)  a party  to a  civil,  criminal,
administrative or investigative proceeding.

      Article  VIII of the  Company's  Restated  Bylaws  further  provides  that
expenses  incurred by a director or officer in  defending  any civil,  criminal,
administrative or investigative  action, suit or proceeding shall be paid by the
Company in advance of the final  disposition of such action,  suit or proceeding
upon receipt of an  undertaking  by or on behalf of such  director or officer to
repay such amount if it shall  ultimately be determined  that such person is not
entitled to be indemnified by the Company as authorized in Article VIII.



                                     II-4

<PAGE>



                                   PART F/S

      The Company's  financial  statements for the years ended December 31, 1998
and 1997,  and for the quarter  ended March  31,1999,  have been examined to the
extent  indicated in their  reports by  Schvaneveldt  and  Company,  independent
certified  accountants,  and have been  prepared in  accordance  with  generally
accounting  principles  and pursuant to  Regulation  S-B as  promulgated  by the
Commission.  These financial  statements are included herein on the following 32
pages, in response to Part F/S of this Form 10-SB.

                                    F/S-1

<PAGE>



                       Advanced Business Sciences, Inc.
                         (A Development Stage Company)

                             Financial Statements
                               March 31, 1999 &
                           December 31, 1998 & 1997


                                    F/S-2

<PAGE>



                       Advanced Business Sciences, Inc.
                         (A Development Stage Company)


                                     Index

                                                                    Page

Independent Accountants' Audit Report......................................F/S-4

Financial Statements
   Balance Sheets....................................................F/S-5-F/S-6
   Statements of Operations..........................................F/S-7-F/S-8
   Statements of Stockholders' Equity (Deficit).....................F/S-9-F/S-12
   Statements of Cash Flows........................................F/S-13-F/S-14
   Notes to Financial Statements...................................F/S-15-F/S-28

Supplemental Information
   Independent Accountants' Audit Report on Supplemental Information......F/S-30
   Schedules of Expenses...........................................F/S-31-F/S-32


                                    F/S-3

<PAGE>










                          Independent Auditors Report

Board of Directors
Advanced Business Sciences, Inc.

I have audited the accompanying  balance sheets of Advanced  Business  Sciences,
Inc.,  as of March  31,  1999,  December  31,  1998 and  1997,  and the  related
statements of operations,  stockholders'  equity,  and cash flows for the period
January 1, 1999 to March 31,  1999 and the years  ended  December  31,  1998 and
1997.  These  financial  statements  are  the  responsibility  of the  Company's
management.  My  responsibility  is to express  an  opinion  on these  financial
statements based on my audit.

I conducted my audit in accordance with generally  accepted auditing  standards.
Those standards  require that I plan and perform the audit to obtain  reasonable
assurance   about  whether  the  financial   statements  are  free  of  material
misstatements. An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the accounting  principles used and the significant  estimates made by
management, as well as evaluating the overall financial statements presentation.
I believe that my audit provides a reasonable basis for my opinion.

The accompanying  financial  statements have been prepared  assuming the Company
will  continue as a going  concern.  As discussed  in Note #15 to the  financial
statements,  the Company has an  accumulated  deficit at March 31,  1999.  These
factors raise  substantial  doubt about the  Company's  ability to continue as a
going concern.  Management's plans in regard to these matters are also discussed
in Note #15. The financial  statements do not include any adjustments that might
result from the outcome of this uncertainty.

In my opinion,  the aforementioned  financial  statements present fairly, in all
material respects,  the financial position of Advanced Business Sciences,  Inc.,
as of March 31,  1999,  December  31,  1998 and  1997,  and the  results  of its
operations  and its cash flows for the period  January 1, 1999 to March 31, 1999
and the years ended  December 31, 1998 and 1997,  in conformity  with  generally
accepted accounting principles.




Salt Lake City, Utah
June 7, 1999

                                    F/S-4

<PAGE>


<TABLE>

                             Advanced Business Sciences, Inc.
                               (A Development Stage Company)
                                      Balance Sheets
                        March 31, 1999, December 31, 1998 and 1997

<CAPTION>
                                                             1999        1998        1997
                                                             ----        ----        ----

<S>                                                       <C>          <C>          <C>

Current Assets
   Cash and Cash Equivalents........................     $ 12,057  $   377,592   $      300
   Receivables
     Trade Accounts ................................       50,846       13,995       11,461
     Employees .....................................       14,720       26,309          345
     Stock Subscription Receivable (note 11) .......      564,452      599,452          -0-
   Inventory .......................................      654,389      535,055      582,108
   Prepaid Expenses.................................      148,830       16,212        5,000
                                                          -------       ------        -----


      Total Current Assets .........................    1,445,294    1,568,615      599,214
                                                        ---------    ---------      -------


Property and Equipment
   Furniture and Equipment (note 4).................      603,118      571,779      549,514
   Leasehold Improvements (note 4)..................       16,326       16,326       77,585
   Leased Equipment (note 4)........................      148,533      194,236       29,039
   Intellectual Property (notes 4 & 8)..............      169,000      169,000          -0-
                                                          -------      -------           -



      Total Cost ...................................      936,977      951,341      656,138

      Less Accumulated Depreciation and Amortization      398,551      346,277      237,402
                                                          -------      -------      -------

      Net Book Value ...............................      538,426      605,064      418,736
                                                          -------      -------      -------
Other Assets
   Rent and Utility Deposits .......................        4,073        4,073       11,950
   Patents (note 5).................................       13,631       13,631       15,145
   Advance to Comguard (note 9).....................       88,514       66,992          -0-
   Investment in Comguard (note 9)..................        2,191        2,191          -0-
                                -                           -----        -----           -
      Total Other Assets ...........................      108,409       86,887       27,095
                                                          -------       ------       ------

      Total Assets .................................   $2,092,129   $2,260,566   $1,045,045
                                                       ==========   ==========   ==========


</TABLE>



    The accompanying notes are an integral part of these financial statements

                                          F/S-5

<PAGE>

<TABLE>


                             Advanced Business Sciences, Inc.
                               (A Development Stage Company)
                                Balance Sheets -Continued-
                        March 31, 1999, December 31, 1998 and 1997

<CAPTION>


                                                             1999        1998        1997
                                                             ----        ----        ----
 <S>                                                     <C>        <C>         <C>
Current Liabilities
   Cash in Bank Overdraft............................  $     -0-    $ 206,230   $  17,411
   Accounts Payable..................................     393,208     392,016     439,446
   Payroll Taxes Accrued and Withheld (note 6).......      57,794     220,440     228,739
   Accrued Interest..................................      41,512      19,795      25,019
   Accrued Wages.....................................         -0-      15,200      41,769
   Note Payable Short Term Debt (note 12)............   2,895,780   2,034,768      87,453
   Current Portion of Long-Term Debt (note 12).......      20,039      25,978     133,948
                                                           ------      ------     -------

      Total Current Liabilities                         3,408,333   2,914,427     973,785
                                                        ---------   ---------     -------

Long-Term Liabilities
   Long-Term Debt, Less Current Portion (note12)......    123,364     123,675      80,000
                                                          -------     -------      ------

       Total Liabilities                                3,531,697   3,038,102    1,053,785
                                                        ---------   ---------    ---------

Commitments and Contingency (note 17)

Stockholders' Equity (Deficit) (note 14)
   Preferred Stock 1,000,000 Shares Authorized at $.01
     Par Value; None Issued
   Common Stock 50,000,000 Shares Authorized at $.001
     Par Value; 13,285,494 12,633,494 and 7,487,099
     Shares Issued and Outstanding Respectively
     Retroactively Restated...........................     13,286      12,634        7,487
   Paid-in Capital....................................  8,047,094   7,982,546    5,310,477
   Deficit Accumulated During the Development Stage... (9,499,948)( 8,772,716)  (5,326,704)

      Total Stockholders' Equity (Deficit)             (1,439,568) (  777,536)  (    8,740)
                                                       ----------    ---------   ---------

      Total Liabilities and Stockholders'
                         Equity (Deficit)            $  2,092,129   $2,260,566  $1,045,045
                                                     ============   ==========  ==========

</TABLE>


    The accompanying notes are an integral part of these financial statements

                                          F/S-6

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
                            Statements of Operations
              For the Period January 1, 1999 to March 31, 1999 and
                the Years Ended December 31,1998 and 1997 and the
        Period from August 11, 1989 (Date of Inception) to March 31, 1999

<CAPTION>

                                           Period Ended  Year Ended  Year Ended  (Inception)
                                                  March    December    December    to March
                                               31, 1999    31, 1998    31, 1997    31, 1999
                                             ----------- ----------- ----------- -----------
<S>                                           <C>         <C>         <C>       <C>

Revenues.............................        $   48,869  $   49,353  $   26,100 $   173,362

Cost of Sales........................            38,124      90,146      22,867     185,655
                                                 ------      ------      ------     -------

Gross Profit (Loss)..................            10,745  (   40,793)      3,233  (   12,293)
- -------------------

Expenses
   Research and Development..........            33,184     500,628     283,429   1,468,839
   Sales and Marketing...............           127,126     427,120     384,052   1,105,534
   General and Administrative........           523,761   2,176,396   1,548,396   6,956,392
                                                -------   ---------   ---------   ---------

      Total Expenses                            684,071   3,104,144   2,215,877   9,530,765
                                                -------   ---------   ---------   ---------
      Loss from Operations                   (  673,326) (3,144,937) (2,212,644) (9,543,058)

Other Income and (Expense)
   Interest Income...................               -0-         -0-       4,172      14,744
   Other Income......................               -0-         -0-         -0-      84,528
   Loss on Sale of Property and Equipment           -0-        (349)     (2,876)     (9,336)
   Interest Expense.................         (   53,906) (  206,426) (  183,812) (  522,427)
   Asset Abandonment (note 4)........                -0- (   94,300)        -0-  (   94,300)
                           -                          -      ------          -       ------

      Total Other Income and Expense         (   53,906) (  301,075) (  182,516) (  526,791)
                                                 ------     -------     -------     -------

      Loss Before Extraordinary Item and
      Provision for Income Taxes             (  727,232) (3,446,012) (2,395,160)(10,069,849)

Extraordinary Item
   Gain from Extinguishment of Debt,
     Net of Income Taxes (note 16)                   -0-        -0-      569,901     569,901
                                                      -          -       -------     -------

      Loss Before Provisions for Income Taxes(  727,232) (3,446,012) (1,825,259) (9,499,948)

      Provision for Income Taxes                    -0-         -0-         -0-         -0-
                                                     -           -           -           -

      Net Loss                               ($ 727,232)($3,446,012)($1,825,259)($9,499,948)
                                             ========== =========== =========== ===========

</TABLE>

    The accompanying notes are an integral part of these financial statements

                                            F/S-7

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
                            Statements of Operations
              For the Period January 1, 1999 to March 31, 1999 and
                    the Years Ended December 31,1998 and 1997
<CAPTION>

                                                       Period Ended  Year Ended  Year Ended
                                                              March    December    December
                                                           31, 1999    31, 1998    31, 1997
                                                         ----------- ----------- -----------
<S>                                                       <C>         <C>        <C>

      Loss Per Share Before Extraordinary Items          ($     .06) ($     .37) ($.     44)

      Loss Per Share After Extraordinary Items           (      .06) (      .37) (      .33)

      Weighted Average Shares Outstanding as
      Retroactively Restated                             12,935,494   9,391,265   5,405,367

</TABLE>


    The accompanying notes are an integral part of these financial statements

                                            F/S-8

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
              Statements of Stockholders' Equity (Deficit)
             For the Period from January 5, 1992 to March 31, 1999
<CAPTION>
                                                                                    Deficit
                                                                                Accumulated
                                                                                 During the
                                                    Common Stock     Paid-in    Development
                                              Shares   Par Value     Capital          Stage
                                              ------   ---------     -------        -----
<S>                                      <C>          <C>         <C>           <C>
Balance, January 5, 1992                        -0-  $       -0- $       -0-    $      -0-

Issuance of Stock for Cash at $0.0012
Per Share Retroactively Restated          3,300,000        3,300         700

Net Loss for Year Ended
December 31, 1992                                                               (    5,870)
                  -------------------------------------------------------------------------

Balance, December 31, 1992                3,300,000        3,300         700    (    5,870)

Net Loss for Year Ended
December 31, 1993                                                               (    7,734)
                   ------------------------------------------------------------------------

Balance, December 31, 1993                3,300,000        3,300         700    (   13,604)

Net Income for Year Ended
December 31, 1994                                                                    17,924
                   ------------------------------------------------------------------------

Balance, December 31, 1994                3,300,000        3,300         700          4,320

Issuance of Stock for Services and the
Assignment, Rights, Title and Interest
in an Invention Disclosed in the
Company's Patent Application on
January 1, 1995 at $.0012 Per Share
Retroactively Restated                      583,688          584         123

Capital Contributed by a Shareholder                                   3,200

Issuance of Stock through a Private
Placement Memorandum at $3.64
Per Share Retroactively Restated            294,360          294   1,070,106

Cost of Private Placement                                         (   54,192)

</TABLE>
    The accompanying notes are an integral part of these financial statements

                                          F/S-9

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
             Statements of Stockholders' Equity (Deficit)-Continued-
              for the Period from January 5, 1992 to March 31, 1999

<CAPTION>
                                                                                    Deficit
                                                                                Accumulated
                                                                                 During the
                                                    Common Stock     Paid-in    Development
                                              Shares   Par Value     Capital          Stage
                                              ------   ---------     -------          -----
<S>                                        <C>         <C>         <C>          <C>

Net Loss for the Year Ended
December 31, 1995                                                               (  659,788)
                                             ----------------------------------------------

Balance, December 31, 1995                 4,178,048       4,178   1,019,937    (  655,468)

Issuance of Stock through a Private
Placement Memorandum at $3.64 Per
Share Retroactively Restated                 118,140         118     429,482

Cost of Private Placement                                         (   56,431)

Cancellation of  Stock at $.001 Per
Share Retroactively Restated                (577,500)  (     577)        577

Issuance of Stock at $.01 Per Share
in Connection with Notes Payable
Retroactively Restated                        412,500         412  (     412)

Issuance of Stock Related to the
Conversion of 10% Convertible
Sub-Ordinate Debenture at $6.06
Per Share Retroactively Restated               41,250          41     249,959

Net Loss for the Year Ended
December 31, 1996                                                               (2,845,977)
                                             ----------------------------------------------

Balance, December 31, 1996                  4,172,438       4,172   1,643,112   (3,501,445)

Issuance of Stock at $.01 Per Share
in Connection with Notes Payable
Retroactively Restated                        165,000         165  (      165)

Issuance of Stock Related to
Conversion of 10% Convertible
Subordinated Debentures at $6.06
Per Share Retroactively Restated               16,500          17      99,983
</TABLE>


    The accompanying notes are an integral part of these financial statements

                                          F/S-10

<PAGE>
<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
             Statements of Stockholders' Equity (Deficit)-Continued-
             for the Period from January 5, 1992 to March 31, 1999
<CAPTION>
                                                                                    Deficit
                                                                                Accumulated
                                                                                 During the
                                                    Common Stock     Paid-in    Development
                                              Shares   Par Value     Capital          Stage
                                              ------   ---------     -------          -----
<S>                                        <C>         <C>         <C>          <C>
Cost of Private Placement                                         (   20,400)

Issuance of  Stock for Services at $.01
Per Share Retroactively Restated              82,500          82  (       72)

Issuance of Stock Related to
Conversion of Sub-Ordinated
Debentures, Notes and Accrued
Interest, Retroactively Restated           1,349,617       1,350   1,871,259

Issuance of Stock Related to Notes
Payable and Accrued Interest
Retroactively Restated (note 7)              799,507         800   1,682,102

Issuance of Stock Related to Notes
Payable and Accrued Interest
Retroactively Restated                        12,375          12      29,988

Issuance of Stock Related to
Payments of Bonuses                            2,063           2       5,107

Issuance of Shares Related to Finder
Fees for "Reverse Acquisition Takeover"
of Sage Analytical International, Inc.        450,000        450

Shares Issued to Shareholders of Sage
Analytical International, Inc., Prior to
"Reverse Acquisition Takeover"                437,099        437  (      437)

Net Loss for the Year Ended
December 31, 1997                                                               (1,825,259)
                                             ----------------------------------------------

Balance, December 31, 1997                  7,487,099      7,487   5,310,477    (5,326,704)


</TABLE>


    The accompanying notes are an integral part of these financial statements

                                          F/S-11

<PAGE>

<TABLE>

                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
             Statements of Stockholders' Equity (Deficit)-Continued-
             for the Period from January 5, 1992 to March 31, 1999
<CAPTION>
                                                                                    Deficit
                                                                                Accumulated
                                                                                 During the
                                                    Common Stock     Paid-in    Development
                                              Shares   Par Value     Capital          Stage
                                              ------   ---------     -------          -----
<S>                                        <C>         <C>         <C>          <C>
Shares Issued for Comguard Leasing
and Financial, Inc., Acquisition           2,191,145       2,191

Consultation Fees Comguard Acquisition
at $0.10 Per Share                           242,500         243      24,007

Shares Issued for Employee Bonuses
at $0.10 Per Share                           457,750         458      45,317

Private Placement Memorandum
Proceeds at $2.00 Per Share                1,250,000       1,250   2,498,750

Shares Issued for Line of Credit
Guarantor Fees at $0.10 Per Share          1,000,000       1,000      99,000

Shares Sold Pursuant to Warrant
Exercise at $1.00 Per Share                    5,000            5       4,995

Loss for Year Ended
December 31, 1998                                                               (3,446,012)
                                             ----------------------------------------------

Balance, December 31, 1998                12,633,494       12,634   7,982,546   (8,772,716)

Shares Issued for 1998 Employee
Bonuses at $0.10 Per Share                   152,000          152      15,048

Shares Issued for Line of Credit
Guarantor Fees at $0.10 Per Share            500,000          500      49,500

Loss for Period Ended
March 31, 1999                                                                  (  727,232)
                                             ----------------------------------------------

Balance, March 31, 1999                   13,285,494  $    13,286  $8,047,094  ($9,499,948)
                                          =================================================
</TABLE>


    The accompanying notes are an integral part of these financial statements

                                          F/S-12

<PAGE>

<TABLE>

                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
                            Statements of Cash Flows
                For the Period January 1, 1999 and March 31, 1999
              and the Years Ended December 31, 1998 and 1997 Period
           from August 11, 1989 (Date of Inception) to March 31, 1999
<CAPTION>

                                            Period Ended  Year Ended  Year Ended  (Inception)
                                                   March    December    December    to March
                                                31, 1999    31, 1998    31, 1997    31, 1999
                                               ----------  ----------  ----------  ----------
<S>                                            <C>         <C>         <C>        <C>

Cash Flows from Operating Activities
  Net Loss                                     ($727,232)($3,446,012)($1,825,259)($9,499,948)
  Adjustments to Reconcile Net Loss to Net Cash
  Used in Operating Activities
   Loss on Assets Write Off                           -0-      94,300         -0-      94,300
   Loss on Inventory Obsolence                        -0-     202,996         -0-     202,996
   Rounding                                     (      2)          -0-        -0-          -0-
   Depreciation and Amortization                  52,274      172,221     130,917     462,159
   Loss on Sale of Property and Equipment             -0-         349       2,876       9,336
   Ex enses Paid by Issuance of Stock
     in Lieu of Cash                              50,000      170,025       5,567     225,592
   Gain from Forgiveness of Debt                      -0-          -0-  ( 569,901)  ( 569,901)
   Changes in Operating Assets and Liabilities
     (Increase) Decrease in
        Trade Accounts Receivable                (36,851)      (2,534)     (5,984)    (50,846)
     (Increase) Decrease in
        Employee Receivables                      11,589      (25,964)      4,655     (14,720)
     (Increase) Decrease in Inventory           ( 73,631)      47,053    (115,467)   (654,389)
     (Increase) Decrease in Prepaid Expenses    (132,618)      11,212       6,314    (148,830)
     Increase (Decrease) in Accounts Payable       1,192      (47,430)    110,827     393,208
     Increase (Decrease) in Payroll
         Taxes Accrued                          (162,646)      (8,299)    206,744      57,794
     Increase (Decrease) in Accrued Interest      21,717       (5,224)    (18,653)     41,512
     I(crease (Decrease) in Accrued Wages       ( 15,200)     (26,569)    (24,113)         -0-
     (Increase) Decrease in Advances
        to Stockholders                               -0-         -0-   (  14,748)         -0-
                                             --------------------------------------------------

      Net Cash Used In Operating Activities    (1,011,408) (2,863,876) (2,106,225) (9,451,737)

Cash Flows from Investing Activities
  Proceeds from Sale of Property
          and Equipment                                -0-         -0-     30,510      31,160
  Purchase of Property and Equipment              (22,387)  ( 130,466)  (  29,039)  ( 775,043)
  (Increase) Decrease in Rent and Utility Deposit      -0-      7,877      (3,780)     (4,073)
  (Increase) in Patents                                -0-         -0-  (   4,390)  (  15,145)
  Purchase of Intellectual Property                         ( 169,000)         -0-  ( 169,000)
  Funds Advanced to Comguard                      (21,522)  (  66,992)         -0-  (  88,514)
                                             --------------------------------------------------

      Net Cash Used in Investing Activities     (  43,909)  ( 358,581)  (   6,699) (1,020,615)
</TABLE>

    The accompanying notes are an integral part of these financial statements

                                            F/S-13

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                          (A Development Stage Company)
                            Statements of Cash Flows
                For the Period January 1, 1999 and March 31, 1999
              and the Years Ended December 31, 1998 and 1997 Period
           from August 11, 1989 (Date of Inception) to March 31, 1999
<CAPTION>

                                            Period Ended  Year Ended  Year Ended  (Inception)
                                                   March    December    December    to March
                                                31, 1999    31, 1998    31, 1997    31, 1999
                                               ----------  ----------  ----------  ----------
<S>                                            <C>         <C>         <C>        <C>
Cash Flows from Financing Activities
  Increase (Decrease) in Notes Payable Banks          -0-   1,970,473    120,100   2,895,780
  Proceeds from Long-Term Debt                   897,013   (   87,453) 2,397,000   4,144,081
  Repayment of Long-Term Debt                    (36,001)         -0-  ( 342,286)         -0-
  Proceeds from Issuance of Common Stock              -0-   2,505,000         -0-  4,009,000
  Increase (Decrease) in Banks Overdraft        (206,230)    (188,819)   (63,990)         -0-
  (Increase) Decrease in Notes Receivable
   Stockholders                                   35,000    ( 599,452)        -0-  ( 599,452)
  Cash Receivable in Note Receivable Stockholder      -0-          -0-        -0-     35,000
                                                       -            -          -      ------

      Net Cash Provided by Financing Activities  689,782    3,599,749  2,110,824  10,484,409
                                                 -------    ---------  ---------  ----------
      Increase (Decrease) in Cash
      and Cash Equivalents                     ( 365,535)     377,292  (   2,100)     12,057
                                               ---------      -------  ----------     ------

      Cash and Cash Equivalents,
      Beginning of Period                        377,592         300       2,400         -0-
                                                 -------         ---       -----          -

      Cash and Cash Equivalents,
      End of Period                         $     12,057   $ 377,592   $     300  $  12,057
                                            ============   =========   =========  =========

Disclosure from Operating Activities
  Interest                                       $53,905   $ 206,426   $ 183,812  $ 561,965
  Taxes                                               -0-         -0-         -0-        -0-
</TABLE>

    The accompanying notes are an integral part of these financial statements

                                            F/S-14

<PAGE>




                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                         Notes to Financial Statements

NOTE #1 - Organization and Nature of Business

Advanced Business Sciences,  Inc., (the Company) was incorporated under the laws
of the  state of  Colorado  on June 13,  1983,  under the name  "Sage  Institute
International,  Inc." A  Delaware  Corporation,  using the name  Sage  Analytics
International,  Inc., was incorporated on July 17, 1986 and on September 2, 1986
the Company was reincorporated as a Delaware Corporation by merging the Colorado
Corporation with assets into the Delaware Corporation.

On December 17, 1997, the shareholders of Advanced  Business  Sciences,  Inc., a
Nebraska Corporation, concluded a share exchange with the Company. Following the
exchange of shares the Nebraska  Corporation  became the wholly owned subsidiary
of the Company and control of the Company was transferred to the shareholders of
the Nebraska Corporation.

The purpose for which the Company is organized is to own, engage in, operate and
carry  on any  lawful  business,  and to do all  things  incidental  thereto  or
connected  therewith  which  are not  forbidden  by the  laws of the  states  of
Delaware  and  Nebraska.  The Company  designs,  develops,  produces,  sells and
supports wireless  products and services  relating to the tracking,  monitoring,
and  reporting of  individuals  and things.  Currently  the  Company's  business
relates  to  criminal  justice  applications  for house  arrest  and  electronic
monitoring.

The Company is considered to be a development stage company.

NOTE #2 - Significant Accounting Policies

A.    The Company uses the accrual method of accounting.
B.    Revenues and directly  related  expenses are recognized in the period when
      the goods are shipped to the customer.
C.    The Company considers all short term,  highly liquid  investments that are
      readily  convertible,  within  three  months,  to  known  amounts  as cash
      equivalents. The Company currently has no cash equivalents.
D.    Primary  Earnings  Per Share  amounts  are based on the  weighted  average
      number of shares  outstanding  at the dates of the  financial  statements.
      Fully Diluted Earnings Per Share shall be shown on stock options and other
      convertible issues that may be exercised within ten years of the financial
      statement dates.
E.    Inventories:  Inventories  are stated at the lower of cost,  determined by
      the FIFO method or market.
F.    Depreciation:  The cost of property and equipment is depreciated  over the
      estimated  useful  lives of the  related  assets.  The  cost of  leasehold
      improvements is depreciated  (amortized)  over the lesser of the length of
      the related assets or the estimated  lives of the assets.  Depreciation is
      computed on the straight  line method for  reporting  purposes and for tax
      purposes.

                                    F/S-15

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #2 - Significant Accounting Policies -Continued-

G.    Estimates:  The preparation of the financial statements in conformity with
      generally  accepted  accounting  principles  requires  management  to make
      estimates  and  assumptions  that  affect  the  amounts  reported  in  the
      financial  statements and accompanying  notes. Actual results could differ
      from those estimates.
H.    New  Technical  Pronouncements:  In 1997,  SFAS No.  129,  "Disclosure  of
      Information  about  Capital  Structure"  was issued  effective for periods
      ending after  December 15,  1997.  The Company has adopted the  disclosure
      provisions of SFAS No. 129 effective  with the fiscal year ended  December
      31, 1998.

      In June 1997, SFAS No. 130,  "Reporting  Comprehensive  Income" was issued
      effective for fiscal years beginning after December 31, 1997, with earlier
      application  permitted.  The  Company  has  elected  to adopt SFAS No. 130
      effective with the fiscal year ended  December 31, 1998.  Adoption of SFAS
      No.  130 is not  expected  to  have a  material  impact  on the  Company's
      financial statements.

      In June 1997, SFAS No. 131,  "Disclosures  about Segments of an Enterprise
      and  Related  Information"  was  issued for fiscal  year  beginning  after
      December 31, 1997,  with earlier  application  permitted.  The Company has
      elected to adopt SFAS No.  131,  effective  with the  fiscal  years  ended
      December  31,  1998.  Adoption  of SFAS No. 131 is not  expected to have a
      material impact on the Company's financial statements.

NOTE #3 - Reverse Takeover and Recapitalization

Pursuant  to a Plan and  Agreement  of  Reorganization  dated  November 3, 1997,
Advanced Business Sciences,  Inc., a Nebraska Corporation,  (the legal acquiree)
and Sage  Analytics  International,  Inc.,  a Delaware  Corporation,  (the legal
acquirer)  exchanged common stock to give the shareholders of the legal acquiree
control of the legal acquirer.

Shareholders of the legal acquiree  surrendered  100% of the outstanding  shares
(80,000  shares) in exchange for 6,600,000  shares of the legal  acquirer.  Each
share  of the  legal  acquiree  was  exchanged  for  82.5  shares  of the  legal
acquirer's  previously unissued common stock. As part of the agreement the legal
acquirer issued 450,000 shares to persons as finders fees.

Following the exchange the  shareholders  of the legal  acquiree held  6,600,000
shares of the 7,487,099 issued shares of the legal acquirer (88.2%).

On December 18, 1997,  Sage Analytics  International,  Inc., the legal acquirer,
filed a  Certificate  of Amendment  with the  Secretary of State of the state of
Delaware changing its name to Advanced Business Sciences, Inc.

                                    F/S-16

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #3 - Reverse Takeover and Recapitalization -Continued-

The share exchange of a private operating Company,  (Advanced Business Sciences,
Inc.)  into  a   non-operating   public  shell   corporation   (Sage   Analytics
International, Inc.), with no assets or liabilities resulted in the shareholders
of the private company having actual  operating  control of the combined company
after  the  transaction,  and  the  shareholders  of  the  former  public  shell
continuing only as passive investors.

This transaction is considered to be a capital transaction in substance,  rather
than a business  combination.  That is, the  transaction  is  equivalent  to the
issuance of stock by the  private  company  for the net  monetary  assets of the
shell  corporation,  accompanied  by  a  recapitalization.   The  accounting  is
identical to that  resulting from a reverse  acquisition,  except no goodwill or
other intangible is recorded.

APB No., 16,  paragraph 70 states that,  "Presumptive  evidence of the acquiring
corporation  in  combinations  effected  by an  exchange of stock is obtained by
identifying the former common  stockholder  interest of a combined company which
either  retains  or  receives  the larger  portion  of the voting  rights of the
combined corporation.  That corporation should be treated as the acquirer unless
other evidence clearly indicates that another corporation is the acquirer."

Staff  accounting  Bulletin  Topic 2A  affirms  the  above  principle  and gives
guidelines that the post  reverse-acquisition  comparative  historical financial
statements  furnished  for the  legal  acquirer  should  be those  of the  legal
acquiree.

In accordance  with this guideline the outstanding  shares of Advanced  Business
Sciences,  Inc., have been retroactively  restated on the Balance Sheet, and the
Statement of Stockholders'  Equity to give effect to the 82.5 shares for 1 share
exchange.  The retroactively  restated shares have been used in the Computations
for Earnings (Losses) Per Share to preserve comparability of those figures.

NOTE #4 - Property and Equipment and Depreciation Expenses

The Company capitalized the purchase of equipment for merger purchases in excess
of $500 per item.  Capitalized amounts are depreciated over the estimated useful
life of the assets as follows:

                                                              Estimated
      Property & Equipment Useful Life
      Furniture & Equipment  5 to 7 Years
      Leasehold Improvements 15 Years
      Leased Equipment 2 to 3 Years




                                    F/S-17

<PAGE>




                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #4 - Property and Equipment and Depreciation Expenses -Continued-

Property and equipment at cost are as follows:   1999        1998        1997
- ----------------------------------------------   ----        ----        ----
      Furniture & Equipment                  $603,118   $ 571,779   $ 549,514
      Leasehold Improvements                   16,326      16,326      77,585
      Intellectual Property                   169,000     169,000          -0-
      Leased Equipment                        148,533     194,236      29,039

         Total Cost                           936,977     951,341     656,138
         Less Accumulated Depreciation        398,551     346,277     237,402
                                              -------     -------     -------
         Net Book Value                     $538,426    $605,064     $418,736
                                              =======    ========    ========

      Depreciation and Amortization Expenses $52,274     $172,221    $130,917

In 1998,  the  Company  reduced  the size of its office and  warehouse  space in
Omaha,  Nebraska.  Leasehold  improvements and equipment that could not be moved
were written off.

NOTE #5 - Patents

The  Company  has filed  three  Petitions  to the  Commissioner  of Patents  and
Trademarks on an apparatus and methods for continuous  Electronic Monitoring and
Tracking of  individuals.  The  original  application  was filed on December 30,
1994. In 1997 a new Continuation in Part Patent Application was filed to further
pursue protection for the subject matter presented in the original applications.

NOTE #6 - Payroll Taxes

In January 1999, the Company paid the Internal  Revenue  Service  $162,646 which
represented the balance of the withheld and accrued Federal Withholding,  Social
Security and Medicare taxes for the quarterly tax periods  ending  September 30,
1996,  December 31, 1996,  March 31, 1997, June 30, 1997 and September 30, 1997.
After the payment the Company owed $57,794 in penalties and interest  associated
with the  aforementioned  quarterly payroll taxes. The Company has requested the
Internal Revenue Service to abate these penalties and interest.

NOTE #7 -  Restatement  of 1997  Issuance  of  Shares In  Satisfaction  of Notes
     Payable

In 1997, the Company issued 799,507 shares of its common stock, for satisfaction
of debt in the amount of $1,770,355.  In 1998,  the Company  learned that it had
obligations of $87,453 that required payments in cash and was not settled by the
issuance of the shares of stock.  In 1998, the cash  obligation was paid and the
issuance of the 799,507  shares of stock for  $1,770,355 was restated to 799,507
shares of stock issued for satisfaction of debt of $1,682,902.


                                    F/S-18

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #8 - Intellectual Property

In 1998, the Company paid $80,000 and incurred $89,000 as an account payable for
the  design of the  logics  and in source  code for the  software  that runs and
displays the support for house arrest monitoring programs.  The Company will use
the intellectual property to have manufactured to its specification equipment to
be used in its  sales of  monitoring  and  tracking  devises.  The  intellectual
property will be amortized on a per unit basis as the units are purchased.

In 1998,  the Company  purchased a Software  License  Agreement with a developer
from  California,  a license  for the  software of a  technology  for use in the
Global  Position  System  Market.  The Company  paid $4,995 for the  software to
operate the license and  capitalized it as software with a three-year  life. The
License  is of an  unspecified  length of time but the  Company  feels  that the
technology will be outdated with the three-year life period.

NOTE #9 - Acquisition and Rescission of Comguard Leasing and Financial, Inc.

On  August  24,  1998,  the  Company  entered  into  a  Plan  and  Agreement  of
Reorganization,  pursuant  to which the Company  acquired  all of the issued and
outstanding shares of capital stock of Comguard Leasing and Financial,  Inc., an
Illinois  Corporation.  On June 1,  1999,  the  Company,  Comguard  Leasing  and
Financial,  Inc., and the shareholders of Comguard Leasing and Financial,  Inc.,
entered into and agreement  whereby the 2,191,145 shares of the Company's shares
issued to acquire Comguard Leasing and Financial, Inc., would be returned to the
Company  and  the  Company  would  receive  a note  from  Comguard  Leasing  and
Financial,  Inc., in the amount of $109,207 which  represents  the  expenditures
made by the Company on behalf of Comguard Leasing and Financial, Inc.

NOTE #10 - Litigation

The  Company  has  been  named as a  Defendant  in a suit  filed in the  Montana
Eighteenth  Judicial  District Court,  Gallatin County,  Montana.  The complaint
against  the  Company  alleges  breach of a contract  and  requests  an award of
compensatory and  consequential  damages in an amount to be determined at trial,
costs and attorney fees as allowed by law.

The  Company  answered  the  complaint,  has  denied  all  material  allegations
contained in the  complaint,  has asserted  eight  affirmation  defenses and has
asserted a counterclaim.

Insufficient  discovery  has taken place to make an  evaluation of the potential
outcome  of  the  litigation.   The  company  has  accrued  no  amounts  due  in
contemplation of the outcome of the litigation.


                                    F/S-19

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #11 -Stock Subscription Receivable

On   December   30,   1998,   the   Company   issued   to   a   related   party,
(stockholder/officer), 299,726 shares of its common stock at $2.00 per share for
a Stock Subscription Receivable of $599,452. As of June 1, 1999, the Company had
received payment in full of the stock subscription receivable.


NOTE #12 - Short Term and Long Term Debt

The Company has the following short term and long term debt.

<TABLE>
<CAPTION>


Short Term Debt                                      1999          1998        1997
- ---------------                                      ----          ----        ----
<S>                                              <C>             <C>         <C>


Term note payable to a commercial bank #1,
due June 1, 1999, Interest Rate 10.50%.       $ 1,000,000        $ 1,000,000 $     -0-

Term note, payable to a commercial bank
and others #2, due October 5, 1999,
interest at 8% per annum.                         998,767            998,768       -0-

Term note payable to a commercial bank #3,
due January 31, 2000 entered at prime
rate, announced by the bank, plus 2.5%.           897,013                 -0-      -0-

Note payable to shareholder, non interest, due on
demand.                                                -0-            36,000   87,453
                                                        -             ------   ------

         Total Short Term Debt                 $2,895,780         $2,034,768  $87,453
                                               ==========         ==========  =======

</TABLE>

On April 1, 1998, the Company issued 1,000,000 shares to certain  individuals as
consideration  for these  individuals  giving  their  unconditional  guaranty of
indebtedness incurred by the Company with commercial banks #1 and #2.

On March 15,  1999,  the  Company  issued to  certain  directors,  officers  and
stockholders of the Company in the aggregate  500,000 Common Shares and Warrants
to purchase in the aggregate 500,000 Common Shares at an exercise price of $1.00
per share.  The warrants are  exercisable  at any time on or before  October 31,
2000.  These  securities  were given in  consideration  for direct  loans to the
Company or for giving unconditional guaranties to such loans.


                                    F/S-20

<PAGE>




                         Advanced Business Sciences, Inc
                          (A Development Stage Company)
                    Notes to Financial Statements -Continued-

NOTE #12 - Short Term and Long Term Debt -Continued-
<TABLE>
<CAPTION>


Long-Term Debt                                       1999          1998        1997
- --------------                                       ----          ----        ----
<S>                                               <C>           <C>           <C>


Capitalized  equipment  lease,  payable
in twelve (12) monthly  installments  of
$7,605, including imputed interest at 9%,
with a bargain purchase option of $18,
through August 1997. This lease is
currently in default.                            $     -0-     $     -0-     $  33,948

Capitalized  equipment  lease,  payable
in twenty-four  (24) to forty-eight (48)
monthly installments of $1,481, and $1,264
respectively, including imputed interest
at 14.73%, through September 1998.                 63,403        69,653             -0-

10% convertible subordinated debentures,
due June 2002, convertible into shares
of common stock at $500 per share
(pre-reverse  takeover) in accordance
with a Private Placement Memorandum
dated May 15, 1996.                                80,000        80,000        180,000
          --- -----                                ------        ------        -------

      Total Long-Term Debt                        143,403       149,653        213,948

      Less Current Portion                         20,039        25,978        133,948
                                                   ------        ------        -------

         Long-Term Debt                       $   123,364   $   123,675      $  80,000
                                              ===========   ===========      =========

</TABLE>

The aggregate  maturities of long-term  debt for the years ending after December
31, 1998 are as follows:

      Years Ending
      December 31,           Amount
      ------------           ------
      1999              $    25,978
      2000                   20,039
      2001                   13,148
      2002                   90,488
      ----                   ------
            Total       $   149,653
                        ===========


                                    F/S-21

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #13 - Taxes

The  Company  accounts  for  income  taxes in  accordance  with SFAS  No.,  109,
Accounting for Income Taxes, which requires an asset and liability approach to a
financial accounting and reporting for income taxes.  Deferred income tax assets
and  liabilities  are computed  annually for  differences  between the financial
statement and tax bases of assets and liabilities that will result in taxable or
deductible  amounts in the future based on enacted tax laws and rates applicable
to the periods in which the  differences  are expected to affect taxable income.
Valuation  allowances  are  established  when  necessary to reduce  deferred tax
assets to the amount  expected  to be  realized.  Income tax  expense is the tax
payable or refundable  for the period plus or minus the change during the period
in deferred tax assets and liabilities.

The Company has net operating  losses to carryforward for future tax purposes as
follows:

      Year of Loss                  Amount of Loss      Expiration Date
      ------------------            ---------------    ----------------
      December 31, 1995             $     655,468           2015
      December 31, 1996                 2,845,977           2016
      December 31, 1997                 1,825,259           2017
      December 31, 1998                 3,446,012           2018

Net deferred  taxes in the  accompanying  balance  sheets  include the following
components as of December 31, 1998 and 1997:
                                             1998           1997
                                    -------------- --------------
      Deferred Tax Asset            $   2,972,583  $   1,800,939
      Net Operating Loss Carry-
        forward Valuation
        Allowance                   (   2,972,583)    (1,800,939)
                                    --------------    ------------

            Net Deferred Tax Asset  $          -0- $          -0-
                                    =============  ---------------

      Current Tax Expense           $          -0-  $         -0-

The Company  has  established  the  valuation  allowance  at 100% of maximum tax
benefit because it is uncertain if the net loss carryforwards will result in tax
asset benefits.

                                    F/S-22

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #14 - Stockholders' Equity

Preferred Stock

      The Company is authorized to issue  1,000,000  shares of preferred  stock,
      $.01 par value, per share.

      The  Preferred  shares  may be  issued  from  time  to time in one or more
      series.  The Board of Directors is  authorized to fix the number of shares
      of any series of Preferred  shares and to determine the designation of any
      such series.  The Board of Directors  is also  authorized  to determine or
      alter the rights, preferences,  privileges, and restrictions granted to or
      imposed upon any wholly,  unissued series of Preferred  shares and, within
      the limits and restrictions stated in any resolution or resolutions of the
      Board of Directors originally fixing the number of shares constituting any
      series,  to increase  or  decrease  (but not below the number of shares of
      such  series  than  outstanding)  the number of shares of any such  series
      subsequent to the issue of shares of that series.

      No preferred shares are issued.

Common Stock

      The  Company is  authorized  to issue  50,000,000  shares of common  stock
      $0.001 par value, per share.

Common Stock Issued for Services and Other Non-Cash Transactions

      The Company  issued  583,688 post reverse  takeover  shares to acquire the
      assignment,  rights,  titles and interest in an  invention  valued at $707
      disclosed in the Company's Patent Application on January 1, 1995.

      In 1997,  the Company  issued  165,000  post  reverse  takeover  shares as
      incentive for accounts payable. No value assigned to the shares issued.

      In 1997,  the Company  issued  82,500  post  reverse  takeover  shares for
      services rendered valued at $10. An additional 2,063 post reverse takeover
      shares were issued to an employee as payment of bonus compensation  valued
      at $5,103.

      Pursuant to the Plan and Agreement of  Reorganization  between the Company
      and Sage Analytics International,  Inc., the Company issued 450,000 shares
      as finders fees value at $450.



                                    F/S-23

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #14 - Stockholders' Equity -Continued-

      Common shares of the Company's post reverse  takeover stock,  owned by the
      shareholders of Sage Analytics International, Inc., are 437,099 shares.

      Pursuant to a Plan and Agreement of Reorganization  dated August 24, 1998,
      the Company  issued  2,191,145  shares of common  stock to acquire 100% of
      Comguard Leasing and Financial, Inc., an Illinois Corporation, outstanding
      stock. An agreement dated June 1, 1999,  rescinded the agreement of August
      24, 1998 and required the return of the 2,191,145 shares of common stock.

      The Company issued 242,500 shares of its common stock as  compensation  to
      outsiders in  conjunction  with the  acquisition  of Comguard  Leasing and
      Financial,  Inc. These shares will not be returned to the Company pursuant
      to the June 1, 1999, agreement.

      The  Company  issued  457,750  shares of its  common  stock as  payment of
      employee bonuses for 1998 valued at $45,775.

      The Company issued  1,000,000 shares of its common stock to Guarantor's of
      the Companies loans with two Commercial Banks,  (bank #1 and bank #2). The
      guarantor fees were valued at $100,000.

      In 1999,  the Company  issued 152,000 shares of common stock as payment of
      accrued 1998 bonuses to employees valued at $15,200.

      In 1999,  the  Company  issued  500,000  shares  to the  makers  and their
      Guarantors  of the  credit  line at a  Commercial  Bank,  (bank  #3).  The
      Guarantor's fees were valued at $50,000.

Options and Warrants

      Sage Analytics International,  Inc., the legal acquirer, (see Note #3) had
      2,816,500  options,  with exercise prices ranging from a minimum of $0.375
      (pre-split) to a maximum of $3.50 (pre-split). All of these options expire
      no later than November 2003.

      The  legal  acquirer  also  had  141,305  warrants  issued  at the date of
      acquisition,  each of which  entitles  the holder  thereof to purchase ten
      shares of common  stock at $0.625 per share of common  stock  (pre-split).
      All warrants expire in or around June 1999.

      Pursuant to a Private Placement  Memorandum,  the Company issued 1,250,000
      units during 1998. Proceeds of the units provided the Company $2,500,000.


                                    F/S-24

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #14 - Stockholders' Equity -Continued-

      Each unit issued  consisted  of one share of common  stock $.001 par value
      per share and one redeemable common stock purchase  warrant.  Each warrant
      entitles  the holder  thereof to purchase  one share of common  stock at a
      price of $3.00  during the first  year,  $4.00  during the second year and
      $5.00  during the third year,  after which time the  exercise  period will
      expire.  The  exercise  prices  are  subject  to  adjustments  to  prevent
      dilution,  for three years from the date of the  memorandum  (February  1,
      1998).

      The  outstanding  warrants are redeemable at the Company's  option at $.05
      each on 30 days prior  written  notice at any time after the closing price
      of  common  stock  has  equaled  or  exceeded  200% of the then  effective
      exercise price for twenty consecutive trading days.

      Prior to the reverse  takeover as described in Note #3, the legal acquirer
      reverse split its outstanding shares on a one for twenty, basis.

Convertible Debentures and Notes Payable

      In 1997, the Company  issued  2,177,999  post reverse  takeover  shares to
      settle  subordinated  debentures,  notes  payables  and  accrued  interest
      totaling $3,772,964.

Deficit Accumulated in the Development Stage

      The Company is considered to be a development  stage  company.  Operations
      have not produced  significant  revenues and  expenditures  for  operating
      expenses  exceed  revenues by $9,499,948.  This amount is considered to be
      the deficit accumulated during the development stage.

NOTE #15 - Going Concern

The accompanying financial statements of Advanced Business Sciences,  Inc., have
been prepared on a going-concern basis, which contemplates profitable operations
and the satisfaction of liabilities in the normal course of business.  There are
uncertainties  that raise  substantial doubt about the ability of the Company to
continue as a going  concern.  As shown in the  statements  of  operations,  the
Company has not yet achieved  profitable  operations.  As of March 31, 1999, the
Company has insufficient  working capital.  These items raise  substantial doubt
about the ability of the Company to continue as a going concern.

Management presently believes that the Company is in the final development stage
of its electronic  tracking and monitoring  devices and the delivery of services
relating to these devices.  Although there has been substantial  progress in the
development of this technology,  the Company does not have any significant sales
and there can be no assurance that the Company will have any significant sales.

                                    F/S-25

<PAGE>




                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #15 - Going Concern -Continued-

 Management plans to continue financing  development of the Company's technology
through the plan described herein.

Advanced  Business  Sciences,  Inc., has been acquired by a public company.  The
Plan and Agreement  requires the Company  stockholders  to exchange their common
stock for approximately  90% of the common stock in the public company.  The new
public company is proceeding with a private placement offering intended to raise
2.5  million  dollars  to be used  for the  elimination  of debt,  reduction  of
outstanding trade accounts payable, product development and working capital.

The Company's  continuation  as a going concern is dependent upon its ability to
satisfactorily  meet its debt obligations,  meet its product  development goals,
secure new financing and generate  sufficient  cash flows from  operations.  The
financial  statements  do not include  any  adjustments  that might  result from
outcome of these uncertainties.

NOTE #16 - Lease Obligations

The Company  conducts its  operations in leased  facilities and has entered into
leases for warehouse and office space.  In addition the Company has an operating
lease for a telephone  system and voice  processing  system.  The future minimum
lease payments under the three  operating  leases as of December 31, 1999 are as
follows:

      Years Ending Lease
      December 31,           Amount
      ------------           ------
      1999              $    76,735
      2000                   76,735
      2001                   70,340
      ----                   ------
            Total       $   223,810
                        ===========

NOTE #16 - Extinguishment of Debt

The Company was a beneficiary of the stock agreement dated May 6, 1997,  between
the majority stockholder,  Robert D. Brummels, his son, Tim R. Brummels, and ABS
Holding Co., Inc. The terms and conditions of this stock  agreement  resulted in
Robert D. Brummels  assuming  several notes payable to American  Interstate Bank
totaling  $452,608  including  interest.  Robert D. Brummels also assumed a term
note payable to Norwest Bank totaling $102,055 including interest. Additionally,
the  Company  was  released of the notes  payable to Tim R.  Brummels  including
interest totaling $108,000.


                                    F/S-26

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #16 - Extinguishment of Debt -Continued-

In return,  the Company released Robert D. Brummels and Tim R. Brummels of their
obligation   to  the  Company   totaling   $82,981  and  $9,781,   respectively.
Furthermore,  the Company  co-signed an ABS Holding Co.,  Inc.,  note payable to
Robert D. And Tim R. Brummels in the amount of $300,000. Finally, Robert D., and
Tim R. Brummels resigned their positions as Board of Director members, officers,
agents and employees of the Company.  As a result of this stock  agreement,  the
Company recognized a gain of $569,901 resulting from the extinguishment of debt.

NOTE #17 - Contingencies and Commitments

On February 1, 1998,  the Company  issued  1,250,000  units  having an aggregate
purchase price of $2,500,000. A unit consisted on one Common Share and a warrant
to purchase one Common Share at an exercise  price of (1) $3.00 per share during
the first  year,  (2) $4.00 per share  during the second  year and (3) $5.00 per
share  during the third year.  The  warrants  expire  February 1, 2001.  All but
sixteen  investors in this offering  were  accredited  investors.  The Company's
management  believes that this  transaction  was in substantial  compliance with
Rule 506 under  the  Securities  Act;  however,  the  Company  has a  contingent
liability  for the  entire  offering  plus  costs  associated  with  any  future
litigation respecting this matter.

The Company  entered into an Agreement  with a business  executive to act as its
President and Chief  Executive  Officer on February 1, 1999.  Under terms of the
Agreement the executive  will act as President,  Chief  Executive  Officer and a
voting Director of the Company.

The Contract  will  commence on February 1, 1999 and continue  through the third
anniversary of that date.  Thereafter  the contract may be renewed  annually and
continue  on the  same  terms  and  conditions  for  an  indefinite  term  until
termination in accordance with the terms of the Agreement.

The  executive  shall be  compensated  for his  services at the rate of $150,000
annually to be paid in accordance with the Company normal payroll practices.

The executive  shall be eligible for an annual bonus in accordance with criteria
established by the Board each year.

As discussed in note #18, the executive shall receive 1,000,000 shares of common
stock as a hiring incentive.

The  Company  has  signed and filed with the state of  Nebraska  UCC,  financing
statements  attached to the bank #1 loans.  This Financing  Statement covers the
following types (or items) of property. All inventory,  chattel paper, accounts,
equipment and general intangibles;  whether any of the foregoing is owned now or
acquired  later;  all accessions,  additions,  replacements,  and  substitutions
relating to any of the foregoing; all records of any kind relating to any of the
foregoing;  all proceeds relating to any of the foregoing (including  insurance,
general intangibles and other accounts proceeds).


                                    F/S-27

<PAGE>



                        Advanced Business Sciences, Inc
                         (A Development Stage Company)
                   Notes to Financial Statements -Continued-

NOTE #18 - Subsequent Events

On February 1, 1999,  the Company  contractually  committed to its President and
Chief Executive  Officer as a hiring incentive to issue the executive  1,000,000
shares of the Company's  common stock at no cost. Such shares shall be issued as
registered shares. At the date of this report these shares have not been issued.




                                    F/S-28

<PAGE>













                           Supplemental Information


                                    F/S-29

<PAGE>













      Independent Accountants' Audit Report on Supplemental in Formation



Board of Directors and Stockholders
Advanced Business Sciences, Inc.
Omaha, Nebraska


The audit was made for the purpose of forming an opinion on the basic  financial
statements taken as a whole. The supplemental  information presented hereinafter
is presented for purposes of  additional  analysis and is not a required part of
the basic  financial  statements.  Such  information  has been  subjected to the
auditing procedures applied in the audits of the basic financial statements and,
in our opinion,  is fairly  stated in all  material  respects in relation to the
basic financial statements taken as a whole.






June 7, 1999
Salt Lake City, Utah














                                    F/S-30

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                         (A Development Stage Company)
                             Schedules of Expenses
         For the Period January 1, 1999 to March 31, 1999 and the Years
                         Ended December 31,1998 and 1997
<CAPTION>

                                                     March    December    December
                                                  31, 1999    31, 1998    31, 1997
                                                  --------    --------    --------
<S>                                             <C>          <C>        <C>

Expenses
   Salaries and Wages                           194,884      666,650    $  712,370
   Bad Debt                                          -0-          -0-        4,011
   Bank Charges                                     345        1,041         4,549
   Commissions                                       -0-          -0-           -0-
   Consulting Fees                               60,000      380,099        41,103
   Contract Labor                                    -0-      43,392            -0-
   Depreciation and Amortization                 52,274      172,221       130,917
   Donations                                         -0-         325            -0-
   Dues and Subscriptions                         2,911        3,456         9,410
   Employee Hiring Costs                             -0-       2,908            -0-
   Equipment Rental                               4,720       14,190        14,830
   Freight                                        3,864       13,001            -0-
   Insurance:
      General                                    24,614       48,103        45,684
      Health                                     24,514       38,145        41,687
      Officer Life                                1,075           -0-           -0-
   Meals and Entertainment                        3,155       16,391         4,027
   Miscellaneous                                 13,882        5,382        18,851
   Office Supplies                                6,952       24,296         3,961
   Penalties                                         -0-      58,391         2,556
   Postage                                          715        3,115            -0-
   Professional Fees                             17,376      154,510        92,040
   Rent                                          17,575       70,337        84,002
   Repairs and Maintenance                           52        3,266            -0-
   Security Expense                                  -0-       1,140         8,749
   Supplies                                          -0-       8,429            -0-
   Taxes:
      Payroll                                    27,750       51,988        82,356
      Other                                       3,927       25,195         3,539
   Telephone                                     54,756       92,590        92,078
   Training                                          -0-          -0-        1,035
   Travel                                         5,057       36,933        42,972
   Utilities                                      2,804       14,507        17,003
   Vehicle Expense                                  559       23,399        16,699

</TABLE>


        See Independent Accountant's Audit Report on Supplemental Information



                                       F/S-31

<PAGE>

<TABLE>


                          Advanced Business Sciences, Inc.
                            (A Development Stage Company)
                           Schedules of Expenses-Continued
                  For the Period January 1, 1999 to March 31, 1999
                    and the Years Ended December 31,1998 and 1997
<CAPTION>

                                                     March    December    December
                                                  31, 1999    31, 1998    31, 1997
                                                  --------    --------    --------
<S>                                             <C>          <C>        <C>

   Inventory Obsolence                                  -0-    202,996      46,789
   Settlement Costs                                     -0-         -0-     27,178
                                                         -           -      ------

         Total Expenses                         $  523,761  $2,176,396  $1,548,396
                                                ==========  ==========  ==========
</TABLE>



        See Independent Accountant's Audit Report on Supplemental Information



                                       F/S-32

<PAGE>

<TABLE>


                        Advanced Business Sciences, Inc.
                                Expense Schedule
         For the Period January 1, 1999 to March 31, 1999 and the Years
                        Ended December 31, 1998 and 1997
<CAPTION>

                                                       1999        1998        1997
                                                       ----        ----        ----
<S>                                                <C>         <C>         <C>


Research & Development
   Salaries                                       $  19,365    $  95,219   $ 180,185
   Telephone                                          4,066       55,527      71,179
   Materials & Supplies                               9,753      299,900      32,065
   Testing                                               -0-      49,982          -0-
                                                          -       ------           -

         Total Research & Development             $  33,184   $  500,628   $ 283,429
                                                  =========    =========    =========

Sales & Marketing
   Con$ultant Fees                                $      -0-   $      -0-  $  98,443
   Salaries                                          46,875      165,985     197,351
   Payroll Taxes                                      1,810       13,796          -0-
   Contract Labor                                    20,468       16,650          -0-
   Commissions                                           -0-         948          -0-
   Sales Shows Expenses                                  -0-      17,222      10,581
   Marketing/Sales Brochures                         10,318       46,999          -0-
   Advertising                                       29,712       31,305      10,582
   Entertainment                                         -0-       2,715          -0-
   Telephone                                          3,482       18,130       7,672
   Office Supplies                                    2,536        1,814          -0-
   Travel                                            11,925       68,731      28,287
   Supplies & Miscellaneous                              -0-      42,825      31,136
                                                          -       ------      ------

         Total Sales & Marketing                  $ 127,126    $ 427,120   $ 384,052
                                                  =========    =========   =========

</TABLE>



        See Independent Accountant's Audit Report on Supplemental Information



                                       F/S-33

<PAGE>



                                      PART III.

Item 1. Index to Exhibits

   See Item 2 of this Part III.

Item 2. Description of Exhibits


 Exhibit
 Number                   Description
 ------                   -----------

3.01      Restated Certificate of Incorporation of the Company

3.02      Restated Bylaws of the Company

4.01      Form of Common Stock Certificate

10.01     Business Office Lease

10.02     Loan Agreement with Commercial Savings Bank

10.03     Loan Agreement with US Bank, N.A.

10.04     Loan Agreement with Mary Collison

10.05     Loan Agreement with James Pietig

10.06     License with SiRF Technology, Inc.

10.07     Employment Agreement by and between the Company and
          Benjamin J. Lamb

21.01     Subsidiaries of the Company

23.01     Consent of Schvaneveldt & Associates

27.01     Financial Data Schedules



                                     SIGNATURES

   In accordance  with Section 12 of the  Securities  Exchange Act of 1934,  the
registrant caused this registration  statement to be signed on its behalf by the
undersigned, thereunto duly authorized.


                                            ADVANCED BUSINESS SCIENCES, INC.


                                            By: /s/ Benjamin J. Lamb
                                            ------------------------
Date: June 18, 1999                             Benjamin J. Lamb
                                           President and Chief Executive Officer




                                       III-1




                       RESTATED CERTIFICATE OF INCORPORATION
                                         OF
                          ADVANCED BUSINESS SCIENCES, INC.

   The  undersigned,  Benjamin J. Lamb  certifies  that he is the  President and
Chief  Executive  Officer of ADVANCED  BUSINESS  SCIENCES,  INC., a  corporation
organized  and  existing  under the laws of the State of  Delaware,  and  hereby
certifies as follows:

1. The name of the corporation is "ADVANCED BUSINESS SCIENCES, INC.."

2. The original  Certificate  of  Incorporation  was filed with the Secretary of
   State of the  State  of  Delaware  on July  17,  1986,  under  the name  Sage
   Analytics International, Inc.

3. This Restated  Certificate of  Incorporation of the corporation has been duly
   adopted  by  resolutions  of the Board of  Directors  of the  corporation  in
   accordance with the provisions of Section 245 of the General  Corporation Law
   of the State of Delaware  and,  upon filing  with the  Secretary  of State in
   accordance  with  Section  103,  shall  thenceforth  supersede  the  original
   Certificate of  Incorporation,  as heretofore  amended,  and shall, as it may
   thereafter  be  amended  or  supplemented  in  accordance  with its terms and
   applicable law, be the Certificate of Incorporation of the corporation.

4. The text of the  Certificate of  Incorporation  of the  corporation is hereby
   restated to read in its entirety as follows:

                                  ARTICLE 1.  NAME

   The name of the Corporation is ADVANCED BUSINESS SCIENCES, INC.

                       ARTICLE 2.  REGISTERED OFFICE AND AGENT

   The  registered  office of the  Corporation  in the State of  Delaware  is to
located at 220  Continental  Drive,  City of Newark,  County of New Castle;  its
registered   agent  at  the  address  shall  be  American   Guaranty  and  Trust
Corporation.

                                 ARTICLE 3.  PURPOSE

   The purpose of the Corporation is to engage in any lawful act of activity for
which  corporations  may be  organized  under  the  General  Corporation  Law of
Delaware.

                              ARTICLE 4.  CAPITAL STOCK

   The  total  number  of  shares of stock  which  the  corporation  shall  have
authority  to issue is  51,000,000  consisting  of  50,000,000  shares of Common
Stock,  $.001 par value per share (the "Common Stock"),  and 1,000,000 shares of
Preferred Stock, $.01 par value per share (the "Preferred Stock").

   The  Preferred  Stock may be issued from time to time in one or more  series.
The Board of Directors is  authorized  to fix the number of shares of any series
of Preferred shares and to determine the designation of any of such series.  The
Board  of  Directors  is also  authorized  to  determine  or alter  the  rights,
preferences,  privileges, and restrictions granted to or imposed upon any wholly
unissued series of Preferred shares and,


<PAGE>



within the limits and  restrictions  stated in any  resolution or resolutions of
the Board of Directors  originally fixing the number of shares  constituting any
series,  to  increase  or  decrease  (but not below the number of shares of such
series then  outstanding) the number of shares of any such series  subsequent to
the issue of shares of that series.

   Effective  as of December 18, 1997,  each twenty (20)  outstanding  shares of
Common Stock and  Preferred  Stock will be combined and  converted  into one (1)
share each of the Common Stock and Preferred Stock, respectively,  provided that
no  fractional  shares  shall be issued but shall be  rounded up to the  nearest
whole  number.  There shall be no  increase  or  decrease  in the  corporation's
authorized  capital  stock or its par value per share,  or in the  corporation's
capital.

                            ARTICLE 5.  PREEMPTIVE RIGHTS

   No  stockholder  of the  Corporation  shall  have any  preemptive  rights  to
purchase,  subscribe for or otherwise  acquire any share or other  securities of
the Corporation, whether now or hereafter authorized, and any and all preemptive
rights are hereby denied.

                                ARTICLE 6.  DIRECTORS

   The  corporation  shall be under the direction of a board of  directors.  The
board of directors  shall consist of not less than three directors nor more than
15  directors.  The number of directors  within this range shall be as stated in
the  Corporation's  by-laws,  as may be amended from time to time.  The board of
directors  shall divide the directors into three classes and, when the number of
directors  is  changed,  shall  determine  the  class or  classes  to which  the
increased or decreased number of directors shall be apportioned;  provided, that
the  directors  in each class  shall be as nearly  equal in number as  possible;
provided,  further, that no decrease in the number of directors shall affect the
term of any director then in office.

   The classification shall be such that the term of one class shall expire each
succeeding year. The Corporation's board of directors shall initially be divided
into the three  classes  named  Class I, Class II,  and Class III,  with Class I
initially  consisting of one director and Class II and Class III each  initially
consisting of two  directors.  The terms,  classifications,  qualifications  and
election of the board of directors and the filling of vacancies thereon shall be
as provided herein and in the by-laws.  The names of those persons of each class
to serve on the board of directors shall be as follows:

                                      Class I:

           Term of Office Expires at 1987 annual meeting of stockholders:

                                  Thomas E. Sawyer

                                      Class II:

           Term of Office Expires at 1988 annual meeting of stockholders:

                                   R. Keith Jones
                                     Keith Oakes

                                         2

<PAGE>




                                     Class III:

           Term of Office Expires at 1989 annual meeting of stockholders:

                                  Kent G. Stephens
                                   Jon D. Stephens

   Subject  to the  foregoing,  at  each  annual  meeting  of  stockholders  the
successors  to the class of  directors  whose terms  shall then expire  shall be
elected  to hold  office  for a term  expiring  at the third  succeeding  annual
meeting and until their successors shall be elected and qualified.

   Any  vacancy  occurring  in the board of  directors,  including  any  vacancy
created by reason of an increase in the number of directors, shall be filled for
the unexpired term by the concurring vote of a majority of the directors then in
office,  whether or not a quorum,  and any  director so chosen shall hold office
for the  remainder  of the full term of the class of  directors in which the new
directorship  was  created or the  vacancy  occurred  and until such  director's
successor shall have been elected and qualified.

   Any director may be removed with or without cause by an  affirmative  vote of
at least two-thirds of the total votes eligible to be cast by stockholders,  all
stockholders voting together as a single class, at a duly constituted meeting of
stockholders called expressly for that purpose; provided, however, that if there
are at the time one or more  Interested  Stockholders  (as  defined in Article 9
hereof),  directors  may only be  removed  with  cause and in  addition  to such
two-thirds  vote, there must also be an affirmative vote for removal of not less
than a  majority  of the  voting  power of the  issued  and  outstanding  shares
entitled  to vote  thereon  held by  stockholders  other  than  such  Interested
Stockholders.

                          ARTICLE 7.  DIRECTORS' LIABILITY

   The  personal  liability  of the  directors  of  the  Corporation  is  hereby
eliminated to the fullest  extent  permitted by subsection (7) of subsection (b)
of Section 102 of the General  Corporation Law of the State of Delaware,  as the
same may be amended or supplemented.

                                 ARTICLE 8.  BY-LAWS

   The board of  directors  shall  have the power to amend from time to time the
by-laws of the Corporation.  Such action by the board of directors shall require
the affirmative vote of at least a majority of the directors then in office at a
duly constituted meeting of the board of directors called for such purpose.  The
stockholders  may amend by-laws made by the board of  directors.  Such action by
the  stockholders  shall require the affirmative  vote of at least two-thirds of
the total votes cast at a duly  constituted  meeting of stockholders  called for
such  purpose;  provided,  however,  that if  there  are at the time one or more
Interested  Stockholders  (as defined in Article 9 hereof),  in addition to such
two-thirds  vote,  there must also be an affirmative vote for such action of not
less than a majority of the voting  power of the issued and  outstanding  shares
entitled  to vote  thereon  held by  stockholders  other  than  such  Interested
Stockholders.


                                         3

<PAGE>



                      ARTICLE 9.  CERTAIN BUSINESS COMBINATIONS

   The votes of  stockholders  and  directors  required to approve any  Business
Combination  shall  be as set  forth  in this  Article  9.  The  term  "Business
Combination"  is used as defined in  subsection  1 of this  Article 9. All other
capitalized  terms not otherwise defined in this Article 9 or elsewhere in these
Articles of Incorporation are sued as defined in subsection 3 of this Article 9.

   Subsection 1.  Vote Required for Certain Business Combinations.

      A.  Higher  Vote for  Certain  Business  Combinations.  In addition to any
affirmative vote required by law or these Articles of Incorporation,  and except
as otherwise expressly provided in subsection 2 of this Article 9:

      (i) any merger,  consolidation or share exchange of the Corporation or any
   Subsidiary (as hereinafter  defined) with (a) any Interested  Stockholder (as
   hereinafter  defined) or (b) any other corporation  (whether or not itself an
   Interested Stockholder) which is, or after the merger, consolidation or share
   exchange  would be, an Affiliate or Associate  (as the terms are  hereinafter
   defined) of any person who or which was an  Interested  Stockholder  prior to
   the transaction; or

      (ii) any  sale,  lease,  exchange,  mortgage,  pledge,  transfer  or other
   disposition  other than in the usual and regular  course of business ( in one
   transaction or a series of  transactions in any  twelve-month  period) to any
   Interested  Stockholder  or any  Affiliate or  Associate  of such  Interested
   Stockholder, other than the Corporation or any Subsidiary having, measured at
   the time  the  transaction  or  transactions  are  approved  by the  board of
   directors of the Corporation,  an aggregate book value as of directors of the
   Corporation's most recent fiscal quarter of five percent or more of the total
   Market  Value  (as  hereinafter  defined)  of the  outstanding  shares of the
   Corporation  or of its net  worth  as of the end of its  most  recent  fiscal
   quarter or;

      (iii)  the  issuance,   sale,   transfer  or  other   disposition  by  the
   Corporation,   or  any  Subsidiary  (in  one   transaction  or  a  series  of
   transactions)  of any equity  securities of the Corporation or any Subsidiary
   having an aggregate  Market Value of five percent or more of the total Market
   Value  of the  outstanding  shares  of  the  Corporation  to  any  Interested
   Stockholder  or any  Affiliate or Associate  of any  Interested  Stockholder,
   other than the Corporation or any of its Subsidiaries, except pursuant to the
   exercise  of  warrants,  rights  or  options  to  subscribe  to  or  purchase
   securities  offered,  issued or granted pro rata to all holders of the Voting
   Stock  (as  hereinafter  defined)  of the  Corporation  or any  other  method
   affording  substantially  proportionate  treatment  to the  holders of Voting
   Stock; or

      (iv)  the  adoption  of any  plan  or  proposal  for  the  liquidation  or
   dissolution of the Corporation or any Subsidiary  proposed by or on behalf of
   an Interested  Stockholder  or any Affiliate or Associate of such  Interested
   Stockholder, other than the Corporation or any of its Subsidiaries; or

      (v) any  reclassification  of  securities  (including  any  reverse  share
   split),   or   recapitalization   of  the  Corporation,   or  any  merger  or
   consolidation  of the  Corporation  with  any of its  Subsidiaries  or  other
   transaction (whether or not with or into or otherwise involving an Interested
   Stockholder) which has the effect, directly or indirectly, in one transaction
   or a series of transactions,  of increasing the  proportionate  amount of the
   outstanding  shares of any class of equity or  convertible  securities of the
   Corporation or

                                         4

<PAGE>



   any  Subsidiary  which is  directly  or  indirectly  owned by any  Interested
   Stockholder  or any  Affiliate or Associate  of any  Interested  Stockholder,
   other than the corporation or any of its Subsidiaries; or

      (vi) any agreement,  arrangement or understanding providing for any one or
   more actions specified in classes (i) through (v) of this Paragraph A of this
   Subsection  (1);  shall be approved by  affirmative  vote of at least (a) the
   holders of  two-thirds  of the total number of  outstanding  shares of Voting
   Stock  and  (b)  the  holders  of  two-thirds  of  the  voting  power  of the
   outstanding shares of Voting Stock, excluding for purposes of calculating the
   affirmative  vote and the total number of outstanding  shares of voting Stock
   under this clause  (b),  all shares of Voting  Stock of which the  beneficial
   owner is the Interested  Stockholder  involved in the Business Combination or
   any Affiliate or Associate of such  Interest  Stockholder.  Such  affirmative
   vote shall be required notwithstanding the fact that no vote may be required,
   or that a lesser percentage may be specified, by law.

   B. Definition of "Business  Combination." The term "Business  Combination" as
used in this  Article 9 shall mean any  transaction  which is referred to in any
one or more of classes (i) through (v) of paragraph A of this subsection 1.

   Subsection 2.  When Higher Vote is Not Required.

   The  provisions  of subsection 1 of this Article 9 shall not be applicable to
any particular Business Combination, and such Business Combination shall require
only such  affirmative  vote as is  required by law and any other  provision  of
these Articles of  Incorporation,  if all the conditions  specified in either of
the foregoing paragraphs A and B are met:

     A. Approval of Continuing  Directors.  The Business  Combination shall have
been  approved  by a  majority  of  the  Continuing  Directors  (as  hereinafter
defined).

     B. Price and Procedure Requirements.  All of the following conditions shall
have been met:

      (i) The  aggregate  amount  of the  cash  and the  Market  Value as of the
   Valuation  Date (as  hereinafter  defined)  of the  Business  Combination  of
   non-cash consideration to be received per share by holders of common stock in
   such  Business  Combination  shall be at least  equal to the  highest  of the
   following:

         (a)  (if  applicable)  the  highest  per  share  price  (including  any
      brokerage  commissions,  transfer taxes and soliciting dealers' fees) paid
      by the Interested  Stockholder  for any shares of common stock acquired by
      it (1) within the two-year  period  immediately  prior to the first public
      announcement   of  the   proposal  of  the   Business   Combination   (the
      "Announcement  Date")  or (2) in the  transaction  in which it  became  an
      Interested Stockholder, whichever is higher; or

         (b) the  Market  Value per share of common  stock of the same  class or
      series on the  Announcement  Date or on the date on which  the  Interested
      Stockholder became an Interested Stockholder (such latter date is referred
      to in this Article 9 as the "Determination Date"), whichever is higher, or

         (c) the price per share  equal to the Market  Value per share of common
      stock of the same  class or  series  determined  pursuant  to  subdivision
      (i)(b) hereof, multiplied by the ratio of (1) the

                                         5

<PAGE>



      highest per share price (including brokerage  commissions,  transfer taxes
      and soliciting  dealer's fees) paid by the Interested  Stockholder for any
      shares of common  stock of the same class or series  acquired by it within
      the two-year period  immediately prior to the Announcement  Date, over (2)
      the Market  Value per share of common stock of the same class or series on
      the first day in such two-year period on which the Interested  Stockholder
      acquired shares of common stock.

      (iii)  The  aggregate  amount of the cash and the  Market  Value as of the
   Valuation Date of non-cash  consideration to be received per share by holders
   of shares of any class or series of  outstanding  Voting  Stock,  other  than
   common  stock,  shall be at least equal to the highest of the  following  (it
   being  intended  that  the  requirements  of this  paragraph  B(ii)  shall be
   required to be met with respect to every class of  outstanding  Voting Stock,
   whether or not the Interested  Stockholder has previously acquired any shares
   of a particular class of Voting Stock):

         (a)  (if  applicable)  the  highest  per  share  price  (including  any
      brokerage  commissions,  transfer taxes and soliciting dealers' fees) paid
      by the  Interest  Stockholder  for any  shares of such  class or series of
      Voting Stock  acquired by it: (1) within the two-year  period  immediately
      prior  to the  Announcement  Date or (2) in the  transaction  in  which it
      became an Interested Stockholder, whichever is higher; or

         (b) (if applicable) the highest  preferential amount per share to which
      the holders of shares of such class or series of Voting Stock are entitled
      in the event of any voluntary or involuntary  liquidation,  dissolution or
      winding up of the Corporation; or

         (c) the Market  value per share of such class or series of Voting Stock
      on the  Announcement  Date  or on the  Determination  Date,  whichever  is
      higher; or

         (d) the  price per share  equal to the  Market  Value per share of such
      class or series of stock determined pursuant to subdivision (ii)(c) hereof
      multiplied by the ratio of (1) the highest per share price  (including any
      brokerage  commissions,  transfer taxes and soliciting dealers' fees) paid
      by the  Interested  Stockholder  for any  shares of any class or series of
      Voting Stock acquired by it within the two-year period  immediately  prior
      to the  Announcement  Date over (2) the Market Value per share of the same
      class or series of Voting Stock on the first day in such  two-year  period
      on which the Interested  Stockholder acquired any shares of the same class
      or series of Voting Stock.

      (iii) The consideration to be received by holders of a particular class or
   series of  outstanding  Voting  Stock shall be in cash or in the same form as
   the Interested  Stockholder  has previously  paid for shares of such class or
   series of Voting Stock. If the Interested  Stockholder has paid for shares of
   any class or series of Voting Stock with varying forms of consideration,  the
   form of  consideration  for such  class or series of  Voting  Stock  shall be
   either cash or the form used to acquire the largest  number of shares of such
   class or series of Voting Stock previously acquired by it.

      (iv)  After  such   interested   Stockholder   has  become  an  Interested
   Stockholder and prior to the consummation of such Business  Combination:  (a)
   there shall have been no failure to declare and pay the regular date therefor
   any full quarterly  dividends  (whether or not cumulative) on any outstanding
   preferred  stock  of the  Corporation;  (b)  there  shall  have  been  (1) no
   reduction in the annual rate of dividends  paid on any class or series of the
   capital stock of the Corporation (except as necessary to reflect

                                         6

<PAGE>



   any  subdivision  of the capital  stock),  and (2) an increase in such annual
   rate of dividends as necessary to reflect any reclassification (including any
   reverse  share  split),  recapitalization,   reorganization  or  any  similar
   transaction which has the effect of reducing the number of outstanding shares
   of common stock;  and (c) such Interested  Stockholder  shall have not become
   the beneficial owner of any additional shares of capital stock except as part
   of the transaction which results in such Interested  Stockholder  becoming an
   Interested  Stockholder or by virtue of  proportionate  stock splits or stock
   dividends.

   The provisions of  subdivisions  (iv) (a) and (iv) (b) of this  subsection do
not  apply if such  actions  shall  have  been  approved  by a  majority  of the
Continuing  Directors  and  if no  Interested  Stockholder  or an  Affiliate  or
Associate of the Interested  Stockholder  voted as a director of the Corporation
in a manner inconsistent with such subdivisions, and the Interested Stockholder,
within  ten  days  after  any  act or  failure  to act  inconsistent  with  such
subdivisions, notifies the board of directors of the Corporation in writing that
the Interested  Stockholder  disapproves  thereof and requests in god faith that
the board of directors rectify such act or failure to act.

      (v)  After  such   Interested   Stockholder   has  become  an   Interested
   Stockholder, such Interested Stockholder shall not have received the benefit,
   directly or indirectly  (except  proportionately  as a  stockholder),  of any
   loans, advances, guarantees, pledges or other financial assistance or any tax
   credits or other tax  advantages  provided by the  Corporation  or any of its
   Subsidiaries  (whether in anticipation of or in connection with such Business
   Combination or otherwise).

      (vi) A proxy or information  statement  describing  the proposed  Business
   Combination and complying with the  requirements  of the Securities  Exchange
   Act of 1934 and the  rules  and  regulations  thereunder  (or any  subsequent
   provisions  replacing  such  Act,  rules or  regulations)  shall be mailed to
   public  stockholders  of the  Corporation  at  least  25  days  prior  to the
   consummation  of such  Business  Combination  (whether  or not such  proxy or
   information  statement  is  required  to be  mailed  pursuant  to such Act or
   subsequent provisions).

   SubCertain Definitions.

For the purpose of this Article 9:

   A. A "person" shall mean any individual, firm, corporation or other entity.

   B. "Interested Stockholder" shall mean any person (other than the Corporation
or any  Subsidiary  or any other  person  who at the date of  adoption  of these
Articles  of  Incorporation  or the date of the  Agreement  of Merger  with Sage
Institute International, Inc., was the beneficial owner, directly or indirectly,
of 10 percent or more of the voting  power of the Voting  Stock  outstanding  on
such date ) who or which:

         (i) is the beneficial owner,  directly or indirectly,  of 10 percent or
      more of the voting power of the then outstanding Voting Stock; or

         (ii) is an  Affiliate  of the  Corporation  and at any time  within the
      two-year  period  immediately  prior  to the  date  in  question  was  the
      beneficial  owner,  directly or  indirectly,  of 10 percent or more of the
      voting power of the then outstanding Voting Stock.


                                         7

<PAGE>



   C. A "beneficial  owner," when used with respect to any Voting Stock, means a
person:

         (i) that,  individually  or with any of its  Affiliates or  Associates,
      beneficially owns Voting Stock directly or indirectly; or

         (ii) that,  individually  or with any of its  Affiliates or Associates,
      has (a)  the  right  to  acquire  Voting  Stock  (whether  such  right  is
      exercisable  immediately  or only after passage of time),  pursuant to any
      agreement, arrangement or understanding or upon the exercise of conversion
      rights, exchange rights, warrants of options, or otherwise;  (b) the right
      to vote or direct the voting of Voting  Stock  pursuant to any  agreement,
      arrangement  or  understanding;  or (c) of Voting  Stock  pursuant  to any
      agreement, arrangement or understanding; or

         (iii) that,  individually  or with any of its Affiliates or Associates,
      has  any  agreement,  arrangement  or  understanding  for the  purpose  of
      acquiring,  holding,  voting or  disposing  of Voting Stock with any other
      person  that   beneficially   owns,  or  whose  Affiliates  or  Associates
      beneficially own, directly or indirectly, such shares of Voting Stock.

   D.  For  the  purpose  of  determining  whether  a  person  is an  Interested
Stockholder  pursuant to paragraph B of this  subsection 3, the number of shares
of Voting Stock deemed to be  outstanding  shall include  shares deemed owned by
such person through  application  of paragraph C of this  subsection 3 but shall
not include any other shares of Voting  Stock which may be issuable  pursuant to
any  agreement,  arrangement  or  understanding,  or upon exercise of conversion
rights, warrants or options, or otherwise.

   E. "Affiliate" means a person that directly or indirectly through one or more
intermediaries controls, or is controlled by, or is under common control with, a
specified person.

   F. "Associate," when used to indicate a relationship with any person,  means:
(1) any  domestic  or  foreign  corporation  or  organization,  other  than  the
Corporation  or a  subsidiary  of the  Corporation,  of which such  person is an
officer, director or partner or is, directly or indirectly, the beneficial owner
of ten percent or more of any class of equity securities; (2) any trust or other
estate in which such person has a substantial beneficial interest or as to which
person  serves as a  trustee  or in a similar  fiduciary  capacity;  and (3) any
relative or spouse of such  person,  or any  relative of such spouse who has the
same home as such person or who is a director or officer of the  Corporation  or
any of its Affiliates.

   G. "Subsidiary" means any corporation of which Voting Stock having a majority
of the  votes  entitled  to be cast is owned,  directly  or  indirectly,  by the
Corporation.

   H.  "Continuing  Director"  means any member of the board of directors of the
Corporation who is unaffiliated with the Interested Stockholder and was a member
of the  board  of  directors  of the  Corporation  prior  to the  time  that the
Interested  Stockholder (including any Affiliate or Associate of such Interested
Stockholder) became an Interested  Stockholder,  and any successor of Continuing
Director who is unaffiliated with the Interested  Stockholder and recommended to
succeed a Continuing Director by a majority of Continuing  Directors then on the
board of directors of the Corporation.

   I. "Market Value" means:


                                         8

<PAGE>



      (i) in the case of stock,  the highest closing sal price during the 30-day
   period immediately preceding the date in question of a share of such stock on
   the composite tape for New York Stock  Exchange - listed stocks,  or, if such
   stock is not quoted on the composite  tape,  or the New York Stock  Exchange,
   or, if such stock is not listed on such exchange, the principal United States
   securities  exchange  registered under the Securities Exchange Act of 1934 on
   which  such  stock is  listed,  or, if such  share is not  listed on any such
   exchange,  the highest closing sales price or bid quotation with respect to a
   share of such stock during the 30-day  period  preceding the date in question
   on the National Association of Securities Dealers, Inc., Automated Quotations
   System of any system then in use, or if no such quotations are available, the
   fair  market  value  on the  date in  question  of a share  of such  stock as
   determined by the board of directors of the Corporation in good faith; and

      (ii) in the case of  property  other than cash or stock,  the fair  market
   value of such property on the date in question as determined by a majority of
   the board of directors of the Corporation in good faith.

   J.  "Valuation  Date"  means:  (A) For a  business  combination  voted  on by
stockholders,  the latter of the day prior to the date of the stockholders  vote
or the date twenty days prior to the  consummation of the Business  Combination;
and (B) for a Business Combination not voted upon by the stockholders,  the date
of the consummation of the Business Combination.

   K. "Voting Stock" means the then  outstanding  shares of capital stock of the
Corporation entitled to vote generally in the election of directors.

   L. In the event of any Business  Combination in which the  Corporation is the
surviving corporation, the phrase "consideration other than cash to be received"
as used in  paragraphs  B(i) and B(ii) of  subsection  2 of this Article 9 shall
include  the shares of common  stock  and/or  the  shares of any other  class or
series of outstanding Voting Stock retained by the holders of such shares.

   Subsection 4. Powers of the Continuing Directors.

   A  majority  of the  Continuing  Directors  shall  have the power and duty to
determine for the purpose of this Article 9, on the basis of  information  known
to them  after  reasonable  inquiry,  (A)  whether  a  person  is an  Interested
Stockholder,  (B) the number of shares of Voting Stock beneficially owned by any
person,  (C) whether a person is an Affiliate  or Associate of another,  and (D)
whether  the  requirements  of  paragraph B of  subsection  2 have been met with
respect  to any  Business  Combination;  and the good faith  determination  of a
majority of the  Continuing  Directors on such matters shall be  conclusive  and
binding for all the purposes of this Article 9.

                             ARTICLE 10.  ANTI-GREENMAIL

   Any direct or indirect  purchase or other  acquisition by the  Corporation of
any  Voting  Stock  (as  defined  in  Article  9  hereof)  from any  Significant
Stockholder (as hereinafter  defined) who has beneficially  owned (as defined in
Article 9 hereof) such Voting Stock for less than two years prior to the date of
such  purchase  or other  acquisition  shall,  except as  hereinafter  expressly
provided,  require the affirmative vote of the holders of at least a majority of
the total number of the then  outstanding  shares of Voting Stock,  excluding in
calculating such shares all Voting Stock  beneficially owned by such Significant
Stockholder.  Such affirmative vote shall be required  notwithstanding  the fact
that no vote may be required, or that a lesser percentage may

                                         9

<PAGE>



be specified,  by law or any agreement  with a national  securities  exchange or
otherwise,  but no such  affirmative  vote shall be required with respect to any
purchase  or other  acquisition  of  Voting  Stock  made as part of a tender  or
exchange  offer by the  Corporation  to purchase  Voting Stock on the same terms
from all  holders  of the same  class of  Voting  Stock and  complying  with the
applicable requirements of the Securities Exchange Act of 1934 and the rules and
regulations thereunder.

For the purpose of this Article 10:

   A.  "Significant   Stockholder"   shall  mean  any  person  (other  than  the
corporation or any  corporation of which a majority of any class of Voting Stock
is owned, directly or indirectly,  by the Corporation or any other person who at
the date of  adoption  of these  Articles  of  Incorporation  or the date of the
Agreement of Merger with Sage Institute International,  Inc., was the beneficial
owner,  directly or indirectly,  of 5 percent or more of the voting power of the
Voting Stock  outstanding  on such date) who or which is the  beneficial  owner,
directly  or  indirectly,  of 5  percent  or more  of the  voting  power  of the
outstanding Voting Stock.

                 ARTICLE 11.  AMENDMENT OF ARTICLES OF INCORPORATION

   Except as set forth in this Article 11 or as otherwise  specifically required
by law, no amendment of any provision of these Articles of  Incorporation  shall
be made unless such  amendment  has been approved both by the board of directors
of the Corporation and by the stockholders of the Corporation by the affirmative
vote of the  holders  of at least a  majority  of the  shares  entitled  to vote
thereon at a duly called annual or special meeting;  provided,  however, that if
such  amendment  is to be the  provisions  set  forth in this  Article  11 or in
Article  6,  7, 8, 9 or 10  hereof,  such  amendment  must  be  approved  by the
affirmative vote of the holders of at least two-thirds of the shares entitled to
vote thereon rather than a majority; provided, further, that if there are one or
more interested  Stockholders  (as defined in Article 9 hereof),  the provisions
set  forth in this  Article  11 or in  Article  6, 7, 8, 9 or 10  hereof  may be
repealed or amended only with the affirmative vote both of (a) the holders of at
least  two-thirds of the total number of outstanding  shares of Voting Stock (as
defined in Article 9 hereof),  and (b) the holders of at least two-thirds of the
total number of  outstanding  shares of Voting Stock,  excluding for purposes of
calculating  both the affirmative  vote and the number of outstanding  shares of
Voting  Stock under this clause (b) all the shares of Voting  Stock of which the
beneficial  owner is an Interested  Stockholder  or an Affiliate or Associate of
such Interested Stockholder (as such terms are defined in Article 9 hereof).

                            ARTICLE 12.  INDEMNIFICATION

   The  Corporation  shall  indemnify  any  person  who was or is a party  or is
threatened  to be made a part to any  threatened,  pending or completed  action,
suit or proceeding, whether civil, criminal,  administrative or investigative by
reason of the fact that he is or was a director,  officer,  employee or agent of
the  Corporation,  or is or was serving at the request of the  Corporation  as a
director, officer, employee or agent of another corporation,  partnership, joint
venture, trust or other enterprise, to the fullest extent permitted by law.

   IN WITNESS WHEREOF,  the corporation has caused this Restated  Certificate of
Incorporation  to be signed by its  President and Chief  Executive  Officer this
10th day of June, 1999.


                                         10

<PAGE>




                                         ADVANCED BUSINESS SCIENCES, INC.



                                         By: /s/ Benjamin J. Lamb
                                         ------------------------
                                              Benjamin J. Lamb
                                         President and Chief Executive Officer



                                         11





                                  RESTATED BYLAWS

                                         OF

                          ADVANCED BUSINESS SCIENCES, INC.


<PAGE>



                                 TABLE OF CONTENTS

                                                                            Page

ARTICLE I.   OFFICES...........................................................1
      Section 1.1 Registered Office ...........................................1
      Section 1.2 Other Offices................................................1

ARTICLE II.   MEETINGS OF STOCKHOLDERS.........................................1
      Section 2.1 Place of Meetings. ..........................................1
      Section 2.2 Annual Meetings. ............................................1
      Section 2.3 Special Meetings. ...........................................1
      Section 2.4 Notice. .....................................................2
      Section 2.5 Adjournments. ...............................................2
      Section 2.6 Quorum. .....................................................2
      Section 2.7 Voting. .....................................................2
      Section 2.8 Consent of Stockholders in Lieu of Meeting. .................3
      Section 2.9 List of Stockholders Entitled to Vote. ......................3
      Section 2.10 Stock Ledger. ..............................................3
      Section 2.11 Conduct of Meetings. .......................................4

ARTICLE III.   DIRECTORS.......................................................4
      Section 3.1 Number and Election of Directors. ...........................4
      Section 3.2 Vacancies. ..................................................4
      Section 3.3 Duties and Powers. ..........................................4
      Section 3.4 Meetings. ...................................................5
      Section 3.5 Quorum. .....................................................5
      Section 3.6 Actions by Written Consent. .................................5
      Section 3.7 Meetings by Means of Conference Telephone. ..................5
      Section 3.8 Committees. .................................................6
      Section 3.9 Compensation. ...............................................6
      Section 3.10 Interested Directors. ......................................6

ARTICLE IV.   OFFICERS.........................................................7
      Section 4.1 General. ....................................................7
      Section 4.2 Election. ...................................................7
      Section 4.3 Voting Securities Owned by the Corporation. .................7
      Section 4.4 Chairman of the Board of Directors. .........................7
      Section 4.5 President. ..................................................8
      Section 4.6 Vice Presidents. ............................................8
      Section 4.7 Secretary. ..................................................8
      Section 4.8 Treasurer. ..................................................9
      Section 4.9 Assistant Secretaries. ......................................9
      Section 4.10 Assistant Treasurers. ......................................9
      Section 4.11 Other Officers. ...........................................10

                                         ii

<PAGE>




ARTICLE V.   STOCK............................................................10
      Section 5.1 Form of Certificates. ......................................10
      Section 5.2 Signatures. ................................................10
      Section 5.3 Lost Certificates. .........................................10
      Section 5.4 Transfers. .................................................11
      Section 5.5 Record Date.................................................11
      Section 5.6 Record Owners. .............................................12

ARTICLE VI.   NOTICES.........................................................12
      Section 6.1 Notices. ...................................................12
      Section 6.2 Waivers of Notice. .........................................12

ARTICLE VII.   GENERAL PROVISIONS.............................................12
      Section 7.1 Dividends. .................................................12
      Section 7.2 Disbursements. .............................................13
      Section 7.3 Fiscal Year. ...............................................13
      Section 7.4 Corporate Seal. ............................................13

ARTICLE VIII.   INDEMNIFICATION...............................................13
      Section 8.1 Power to Indemnify in Actions, Suits or Proceedings
                  other than those by or in the Right of the Corporation. ....13
      Section 8.2 Power to Indemnify in Actions, Suits or Proceedings
                  by or in the Right of the Corporation. .....................14
      Section 8.3 Authorization of Indemnification. ..........................14
      Section 8.4 Good Faith Defined. ........................................14
      Section 8.5 Indemnification by a Court. ................................15
      Section 8.6 Expenses Payable in Advance. ...............................15
      Section 8.7 Nonexclusivity of Indemnification and Advancement
                  of Expenses. ...............................................15
      Section 8.8 Insurance. .................................................16
      Section 8.9 Certain Definitions. .......................................16
      Section 8.10 Survival of Indemnification and Advancement
                   of Expenses. ..............................................16
      Section 8.11 Limitation on Indemnification. ............................17
      Section 8.12 Indemnification of Employees and Agents. ..................17

ARTICLE IX.   AMENDMENTS......................................................17
      Section 9.1 Amendments. ................................................17
      Section 9.2 Entire Board of Directors. .................................17


                                        iii

<PAGE>



                                  RESTATED BYLAWS
                                         OF
                          ADVANCED BUSINESS SCIENCES, INC.
                       (hereinafter called the "Corporation")

                                 ARTICLE I.  OFFICES

Section 1.1  Registered Office.

   The  registered  office of the  Corporation  shall be in the City of  Newark,
County of New Castle, State of Delaware.

Section 1.2  Other Offices.

   The  Corporation  may also have  offices at such other places both within and
without the State of Delaware  as the Board of  Directors  may from time to time
determine.

                        ARTICLE II.  MEETINGS OF STOCKHOLDERS

Section 2.1  Place of Meetings.

   Meetings of the  stockholders  for the election of directors or for any other
purpose shall be held at such time and place, either within or without the State
of Delaware as shall be designated from time to time by the Board of Directors.

Section 2.2  Annual Meetings.

   The Annual  Meetings of  Stockholders  for the election of directors shall be
held on such date and at such time as shall be  designated  from time to time by
the Board of  Directors.  Any other  proper  business may be  transacted  at the
Annual Meeting of Stockholders.

Section 2.3  Special Meetings.

   Unless  otherwise  required by law or by the certificate of  incorporation of
the Corporation,  as amended and restated from time to time (the "Certificate of
Incorporation"),  Special Meetings of Stockholders, for any purpose or purposes,
may be  called  by  either  (i) the  Chairman,  if  there  be one,  or (ii)  the
President,  (iii) any Vice President, if there be one, (iv) the Secretary or (v)
any  Assistant  Secretary,  if there be one,  and  shall be  called  by any such
officer  at the  request  in  writing  of (i) the  Board  of  Directors,  (ii) a
committee of the Board of Directors  that has been duly  designated by the Board
of  Directors  and whose  powers and  authority  include  the power to call such
meetings or (iii)  stockholders  owning a majority  of the capital  stock of the
Corporation  issued and  outstanding  and entitled to vote.  Such request  shall
state the purpose or purposes of the proposed  meeting.  At a Special Meeting of
Stockholders, only such business shall be conducted as shall be specified in the
notice of meeting (or any supplement thereto).

Section 2.4  Notice.

   Whenever  stockholders  are  required  or  permitted  to take any action at a
meeting,  a written  notice of the meeting  shall be given which shall state the
place, date and hour of the meeting, and, in the case of a special


<PAGE>



meeting,  the  purpose or  purposes  for which the  meeting  is  called.  Unless
otherwise  required by law, the written notice of any meeting shall be given not
less than ten nor more than  sixty days  before the date of the  meeting to each
stockholder entitled to vote at such meeting.

Section 2.5  Adjournments.

   Any  meeting  of the  stockholders  may be  adjourned  from  time  to time to
reconvene at the same or some other  place,  and notice need not be given of any
such  adjourned  meeting  if the time and place  thereof  are  announced  at the
meeting  at which  the  adjournment  is taken.  At the  adjourned  meeting,  the
Corporation  may transact any business  which might have been  transacted at the
original  meeting.  If the adjournment is for more than thirty days, or if after
the adjournment a new record date is fixed for the adjourned meeting,  notice of
the adjourned  meeting shall be given to each  stockholder of record entitled to
vote at the meeting.

Section 2.6  Quorum.

   Unless  otherwise  required by law or the Certificate of  Incorporation,  the
holders of a majority of the capital stock issued and  outstanding  and entitled
to vote thereat,  present in person or represented by proxy,  shall constitute a
quorum at all meetings of the  stockholders  for the transaction of business.  A
quorum, once established,  shall not be broken by the withdrawal of enough votes
to leave less than a quorum.  If,  however,  such quorum shall not be present or
represented at any meeting of the  stockholders,  the  stockholders  entitled to
vote thereat,  present in person or  represented  by proxy,  shall have power to
adjourn the meeting from time to time, in the manner provided in Section , until
a quorum shall be present or represented.

Section 2.7  Voting.

   Unless  otherwise  required by law, the Certificate of Incorporation or these
Bylaws, any question brought before any meeting of stockholders,  other than the
election of directors, shall be decided by the vote of the holders of a majority
of the total number of votes of the capital  stock  represented  and entitled to
vote  thereat,  voting  as a single  class.  Unless  otherwise  provided  in the
Certificate of Incorporation, and subject to Section
 hereof,  each  stockholder  represented at a meeting of  stockholders  shall be
entitled to cast one vote for each share of the capital  stock  entitled to vote
thereat held by such  stockholder.  Such votes may be cast in person or by proxy
but no proxy shall be voted on or after  three years from its date,  unless such
proxy provides for a longer period.  The Board of Directors,  in its discretion,
or the officer of the  Corporation  presiding at a meeting of  stockholders,  in
such officer's discretion, may require that any votes cast at such meeting shall
be cast by written ballot.

Section 2.8  Consent of Stockholders in Lieu of Meeting.

   Unless  otherwise  provided in the Certificate of  Incorporation,  any action
required  or  permitted  to be  taken  at  any  Annual  or  Special  Meeting  of
Stockholders of the  Corporation  may be taken without a meeting,  without prior
notice and without a vote,  if a consent or consents in writing,  setting  forth
the action so taken,  shall be signed by the holders of outstanding stock having
not less than the minimum  number of votes that would be  necessary to authorize
or take such action at a meeting at which all shares  entitled  to vote  thereon
were present and voted and shall be delivered to the  Corporation by delivery to
its registered office in the State of Delaware, its principal place of business,
or an officer or agent of the  corporation  having  custody of the book in which
proceedings of meetings of stockholders are recorded. Delivery made to the

                                         2

<PAGE>



Corporation's  registered  office shall be by hand or by certified or registered
mail,  return receipt  requested.  Every written  consent shall bear the date of
signature of each stockholder who signs the consent and no written consent shall
be effective to take the corporate  action  referred to therein  unless,  within
sixty days of the earliest  dated  consent  delivered in the manner  required by
this Section hereof to the Corporation,  written consents signed by a sufficient
number of holders to take action are delivered to the Corporation by delivery to
its registered office in the State of Delaware, its principal place of business,
or an officer or agent of the  Corporation  having  custody of the book in which
proceedings  of meetings of  stockholders  are  recorded.  Prompt  notice of the
taking of the corporate action without a meeting by less than unanimous  written
consent shall be given to those  stockholders  who have not consented in writing
and who, if the action had been taken at a meeting,  would have been entitled to
notice of the meeting if the record date for such meeting had been the date that
written  consents  signed by a  sufficient  number of holders to take the action
were delivered to the Corporation as provided above in this section.

Section 2.9  List of Stockholders Entitled to Vote.

   The  officer of the  Corporation  who has  charge of the stock  ledger of the
Corporation  shall  prepare and make,  at least ten days before every meeting of
stockholders,  a  complete  list  of the  stockholders  entitled  to vote at the
meeting,  arranged  in  alphabetical  order,  and  showing  the  address of each
stockholder and the number of shares registered in the name of each stockholder.
Such list shall be open to the examination of any  stockholder,  for any purpose
germane to the meeting, during ordinary business hours, for a period of at least
ten days  prior to the  meeting  either  at a place  within  the city  where the
meeting  is to be held,  which  place  shall be  specified  in the notice of the
meeting, or, if not so specified,  at the place where the meeting is to be held.
The list shall also be  produced  and kept at the time and place of the  meeting
during the whole time thereof,  and may be inspected by any  stockholder  of the
Corporation who is present.

Section 2.10  Stock Ledger.

   The stock ledger of the Corporation  shall be the only evidence as to who are
the  stockholders  entitled to examine the stock  ledger,  the list  required by
Section hereof or the books of the Corporation, or to vote in person or by proxy
at any meeting of stockholders.

Section 2.11  Conduct of Meetings.

   The Board of Directors of the  Corporation may adopt by resolution such rules
and regulations  for the conduct of the meeting of the  stockholders as it shall
deem  appropriate.  Except  to the  extent  inconsistent  with  such  rules  and
regulations as adopted by the Board of Directors, the chairman of any meeting of
the  stockholders  shall have the right and  authority to prescribe  such rules,
regulations  and  procedures and to do all such acts as, in the judgment of such
chairman,  are  appropriate  for the proper conduct of the meeting.  Such rules,
regulations  or  procedures,  whether  adopted  by the  Board  of  Directors  or
prescribed by the chairman of the meeting, may include, without limitation,  the
following:  (i) the  establishment  of an  agenda or order of  business  for the
meeting;  (ii) the  determination of when the polls shall open and close for any
given  matter to be voted on at the  meeting;  (iii)  rules and  procedures  for
maintaining  order  at the  meeting  and  the  safety  of  those  present;  (iv)
limitations on attendance at or  participation in the meeting to stockholders of
record of the corporation, their duly authorized and constituted proxies or such
other persons as the chairman of the meeting shall  determine;  (v) restrictions
on entry to the meeting after the time fixed

                                         3

<PAGE>



for  the  commencement  thereof;  and  (vi)  limitations  on the  time allotted
to questions or comments by participants.

                               ARTICLE III.  DIRECTORS

Section 3.1  Number and Election of Directors.

   The  Board of  Directors  shall  consist  of not less  than one nor more than
fifteen  members,  the exact  number of which  shall  initially  be fixed by the
Incorporator and thereafter from time to time by the Board of Directors.  Except
as provided in Section hereof,  directors shall be elected by a plurality of the
votes cast at the Annual Meetings of  Stockholders  and each director so elected
shall hold office until the next Annual Meeting of  Stockholders  and until such
director's  successor is duly elected and  qualified,  or until such  director's
earlier death,  resignation or removal. Any director may resign at any time upon
written notice to the Corporation. Directors need not be stockholders.

Section 3.2  Vacancies.

   Unless  otherwise  required  by  law  or the  Certificate  of  Incorporation,
vacancies arising through death, resignation, removal, an increase in the number
of directors or otherwise may be filled only by a majority of the directors then
in office,  though less than a quorum, or by a sole remaining director,  and the
directors  so  chosen  shall  hold  office  until  the next  Annual  Meeting  of
Stockholders and until their successors are duly elected and qualified, or until
their earlier death, resignation or removal.

Section 3.3  Duties and Powers.

   The business and affairs of the Corporation  shall be managed by or under the
direction  of the Board of  Directors  which may exercise all such powers of the
Corporation  and do all such  lawful acts and things as are not by statute or by
the Certificate of  Incorporation or by these Bylaws required to be exercised or
done by the stockholders.

Section 3.4  Meetings.

   The Board of Directors may hold  meetings,  both regular and special,  either
within  or  without  the State of  Delaware.  Regular  meetings  of the Board of
Directors may be held without  notice at such time and at such place as may from
time to time be determined by the Board of  Directors.  Special  meetings of the
Board  of  Directors  may be  called  by the  Chairman,  if  there  be one,  the
President,  or by any director.  Notice thereof stating the place, date and hour
of the  meeting  shall be given to each  director  either  by mail not less than
forty-eight (48) hours before the date of the meeting,  by telephone or telegram
on twenty-four  (24) hours'  notice,  or on such shorter notice as the person or
persons   calling  such  meeting  may  deem  necessary  or  appropriate  in  the
circumstances.

Section 3.5  Quorum.

   Except as otherwise  required by law or the Certificate of Incorporation,  at
all  meetings  of the Board of  Directors,  a majority  of the  entire  Board of
Directors shall  constitute a quorum for the transaction of business and the act
of a majority of the directors present at any meeting at which there is a quorum
shall be the act

                                         4

<PAGE>



of the Board of  Directors.  If a quorum  shall not be present at any meeting of
the Board of Directors,  the directors  present  thereat may adjourn the meeting
from time to time,  without notice other than announcement at the meeting of the
time and place of the adjourned meeting, until a quorum shall be present.

Section 3.6  Actions by Written Consent.

   Unless  otherwise  provided in the  Certificate  of  Incorporation,  or these
Bylaws, any action required or permitted to be taken at any meeting of the Board
of Directors or of any committee thereof may be taken without a meeting,  if all
the members of the Board of Directors or committee,  as the case may be, consent
thereto in writing,  and the  writing or writings  are filed with the minutes of
proceedings of the Board of Directors or committee.

Section 3.7  Meetings by Means of Conference Telephone.

   Unless otherwise provided in the Certificate of Incorporation, members of the
Board of Directors of the Corporation, or any committee thereof, may participate
in a  meeting  of the  Board  of  Directors  or such  committee  by  means  of a
conference telephone or similar  communications  equipment by means of which all
persons participating in the meeting can hear each other, and participation in a
meeting  pursuant to this Section  shall  constitute  presence in person at such
meeting.

Section 3.8  Committees.

   The Board of Directors may designate one or more  committees,  each committee
to  consist of one or more of the  directors  of the  Corporation.  The Board of
Directors  may  designate  one or more  directors  as  alternate  members of any
committee,  who may replace any absent or disqualified  member at any meeting of
any  such  committee.  In the  absence  or  disqualification  of a  member  of a
committee,  and in the absence of a designation  by the Board of Directors of an
alternate  member to replace the absent or  disqualified  member,  the member or
members thereof present at any meeting and not disqualified from voting, whether
or not such  member or members  constitute  a quorum,  may  unanimously  appoint
another  member of the Board of  Directors to act at the meeting in the place of
any absent or disqualified member. Any committee, to the extent permitted by law
and provided in the resolution  establishing such committee,  shall have and may
exercise  all  the  powers  and  authority  of the  Board  of  Directors  in the
management of the business and affairs of the Corporation, and may authorize the
seal of the  Corporation  to be affixed to all papers which may require it. Each
committee  shall keep regular  minutes and report to the Board of Directors when
required.

Section 3.9  Compensation.

   The  directors  may be paid their  expenses,  if any, of  attendance  at each
meeting of the Board of Directors and may be paid a fixed sum for  attendance at
each meeting of the Board of Directors or a stated  salary as director,  payable
in cash or securities.  No such payment shall preclude any director from serving
the  Corporation  in any other  capacity and  receiving  compensation  therefor.
Members of special or standing  committees may be allowed like  compensation for
attending committee meetings.

Section 3.10  Interested Directors.


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<PAGE>



   No contract or  transaction  between the  Corporation  and one or more of its
directors or officers,  or between the  Corporation  and any other  corporation,
partnership,  association,  or other  organization  in which  one or more of its
directors  or officers are  directors or officers or have a financial  interest,
shall be void or voidable solely for this reason, or solely because the director
or  officer  is  present  at or  participates  in the  meeting  of the  Board of
Directors or committee thereof which authorizes the contract or transaction,  or
solely because the director or officer's vote is counted for such purpose if (i)
the material facts as to the director or officer's  relationship or interest and
as to the  contract or  transaction  are  disclosed or are known to the Board of
Directors  or the  committee,  and the Board of  Directors  or committee in good
faith  authorizes  the contract or  transaction  by the  affirmative  votes of a
majority of the disinterested directors, even though the disinterested directors
be less  than a  quorum;  or (ii)  the  material  facts  as to the  director  or
officer's  relationship  or interest and as to the contract or  transaction  are
disclosed or are known to the stockholders entitled to vote thereon, and the con
tract or  transaction  is  specifically  approved  in good  faith by vote of the
stockholders; or (iii) the contract or transaction is fair as to the Corporation
as of the time it is authorized, approved or ratified by the Board of Directors,
a committee thereof or the stockholders.  Common or interested  directors may be
counted in  determining  the  presence  of a quorum at a meeting of the Board of
Directors or of a committee which authorizes the contract or transaction.

                                ARTICLE IV.  OFFICERS

Section 4.1  General.

   The officers of the Corporation shall be chosen by the Board of Directors and
shall include a President, a Secretary and a Treasurer.  The Board of Directors,
in its  discretion,  also may choose a Chairman of the Board of  Directors  (who
must be a  director)  and one or more Vice  Presidents,  Assistant  Secretaries,
Assistant  Treasurers and other  officers.  Any number of offices may be held by
the same  person,  unless  otherwise  prohibited  by law or the  Certificate  of
Incorporation.  The officers of the Corporation  need not be stockholders of the
Corporation  nor,  except in the case of the Chairman of the Board of Directors,
need such officers be directors of the Corporation.

Section 4.2  Election.

   The Board of Directors,  at its first meeting held after each Annual  Meeting
of  Stockholders  (or action by written  consent of  stockholders in lieu of the
Annual Meeting of Stockholders), shall elect the officers of the Corporation who
shall  hold their  offices  for such terms and shall  exercise  such  powers and
perform  such  duties as shall be  determined  from time to time by the Board of
Directors;  and all  officers of the  Corporation  shall hold office until their
successors are chosen and qualified,  or until their earlier death,  resignation
or removal.  Any officer elected by the Board of Directors may be removed at any
time by the affirmative vote of the Board of Directors. Any vacancy occurring in
any office of the  Corporation  shall be filled by the Board of  Directors.  The
salaries  of all  officers  of the  Corporation  shall be fixed by the  Board of
Directors.

Section 4.3  Voting Securities Owned by the Corporation.

   Powers of attorney, proxies, waivers of notice of meeting, consents and other
instruments  relating to securities  owned by the Corporation may be executed in
the  name of and on  behalf  of the  Corporation  by the  President  or any Vice
President or any other officer authorized to do so by the Board of Directors and
any such officer may, in the name of and on behalf of the Corporation,  take all
such action as any such officer may

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<PAGE>



deem advisable to vote in person or by proxy at any meeting of security  holders
of any  corporation in which the  Corporation may own securities and at any such
meeting shall possess and may exercise any and all rights and power  incident to
the  ownership  of  such  securities  and  which,  as  the  owner  thereof,  the
Corporation  might  have  exercised  and  possessed  if  present.  The  Board of
Directors  may,  by  resolution,  from time to time  confer like powers upon any
other person or persons.

Section 4.4  Chairman of the Board of Directors.

   The Chairman of the Board of Directors, if there be one, shall preside at all
meetings of the stockholders and of the Board of Directors.  The Chairman of the
Board of  Directors  shall be the Chief  Executive  Officer of the  Corporation,
unless the Board of Directors  designates  the President as the Chief  Executive
Officer,  and,  except where by law the  signature of the President is required,
the  Chairman  of the Board of  Directors  shall  possess  the same power as the
President  to sign all  contracts,  certificates  and other  instruments  of the
Corporation  which may be  authorized  by the  Board of  Directors.  During  the
absence or disability of the  President,  the Chairman of the Board of Directors
shall exercise all the powers and discharge all the duties of the President. The
Chairman of the Board of Directors  shall also perform such other duties and may
exercise  such other powers as may from time to time be assigned by these Bylaws
or by the Board of Directors.

Section 4.5  President.

   The President shall, subject to the control of the Board of Directors and, if
there be one, the Chairman of the Board of Directors,  have general  supervision
of the business of the Corporation and shall see that all orders and resolutions
of the Board of Directors are carried into effect.  The President  shall execute
all  bonds,  mortgages,  contracts  and  other  instruments  of the  Corporation
requiring a seal,  under the seal of the  Corporation,  except where required or
permitted by law to be  otherwise  signed and executed and except that the other
officers of the Corporation may sign and execute documents when so authorized by
these  Bylaws,  the Board of  Directors  or the  President.  In the  absence  or
disability of the Chairman of the Board of Directors,  or if there be none,  the
President  shall  preside at all meetings of the  stockholders  and the Board of
Directors. If there be no Chairman of the Board of Directors, or if the Board of
Directors shall otherwise designate,  the President shall be the Chief Executive
Officer of the  Corporation.  The President shall also perform such other duties
and may exercise  such other powers as may from time to time be assigned to such
officer by these Bylaws or by the Board of Directors.

Section 4.6  Vice Presidents.

   At the request of the President or in the President's absence or in the event
of the  President's  inability or refusal to act (and if there be no Chairman of
the Board of Directors),  the Vice President, or the Vice Presidents if there is
more than one (in the order designated by the Board of Directors), shall perform
the duties of the  President,  and when so acting,  shall have all the powers of
and be subject to all the restrictions  upon the President.  Each Vice President
shall  perform  such other  duties  and have such  other  powers as the Board of
Directors from time to time may prescribe.  If there be no Chairman of the Board
of Directors and no Vice  President,  the Board of Directors shall designate the
officer of the Corporation  who, in the absence of the President or in the event
of the inability or refusal of the President to act, shall perform the duties of
the President,  and when so acting,  shall have all the powers of and be subject
to all the restrictions upon the President.

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<PAGE>




Section 4.7  Secretary.

   The  Secretary  shall attend all  meetings of the Board of Directors  and all
meetings of  stockholders  and record all the  proceedings  thereat in a book or
books to be kept for that purpose;  the Secretary shall also perform like duties
for  committees of the Board of Directors  when  required.  The Secretary  shall
give,  or cause to be given,  notice of all  meetings  of the  stockholders  and
special meetings of the Board of Directors,  and shall perform such other duties
as may be  prescribed  by the Board of  Directors,  the Chairman of the Board of
Directors or the President,  under whose  supervision the Secretary shall be. If
the Secretary shall be unable or shall refuse to cause to be given notice of all
meetings of the stockholders and special meetings of the Board of Directors, and
if there be no  Assistant  Secretary,  then either the Board of Directors or the
President  may choose  another  officer to cause  such  notice to be given.  The
Secretary shall have custody of the seal of the Corporation and the Secretary or
any Assistant Secretary, if there be one, shall have authority to affix the same
to any  instrument  requiring it and when so affixed,  it may be attested by the
signature of the Secretary or by the signature of any such Assistant  Secretary.
The Board of Directors may give general  authority to any other officer to affix
the seal of the  Corporation  and to attest to the  affixing  by such  officer's
signature.  The  Secretary  shall  see  that  all  books,  reports,  statements,
certificates and other documents and records required by law to be kept or filed
are properly kept or filed, as the case may be.

Section 4.8  Treasurer.

   The Treasurer  shall have the custody of the corporate  funds and  securities
and shall keep full and accurate accounts of receipts and disbursements in books
belonging to the  Corporation  and shall  deposit all moneys and other  valuable
effects in the name and to the credit of the Corporation in such depositories as
may be designated by the Board of Directors.  The Treasurer  shall  disburse the
funds of the  Corporation  as may be ordered by the Board of  Directors,  taking
proper  vouchers for such  disbursements,  and shall render to the President and
the Board of Directors,  at its regular meetings, or when the Board of Directors
so requires,  an account of all  transactions  as Treasurer and of the financial
condition  of the  Corporation.  If  required  by the  Board of  Directors,  the
Treasurer  shall give the Corporation a bond in such sum and with such surety or
sureties as shall be  satisfactory  to the Board of  Directors  for the faithful
performance of the duties of the office of the Treasurer and for the restoration
to the Corporation, in case of the Treasurer's death, resignation, retirement or
removal from office, of all books, papers, vouchers, money and other property of
whatever kind in the  Treasurer's  possession or under the  Treasurer's  control
belonging to the Corporation.

Section 4.9  Assistant Secretaries.

   Assistant  Secretaries,  if there be any,  shall perform such duties and have
such  powers  as from  time to time  may be  assigned  to them by the  Board  of
Directors, the President, any Vice President, if there be one, or the Secretary,
and  in the  absence  of  the  Secretary  or in  the  event  of the  Secretary's
disability  or refusal to act,  shall perform the duties of the  Secretary,  and
when  so  acting,  shall  have  all  the  powers  of and be  subject  to all the
restrictions upon the Secretary.

Section 4.10  Assistant Treasurers.

   Assistant  Treasurers,  if there be any,  shall  perform such duties and have
such  powers  as from  time to time  may be  assigned  to them by the  Board  of
Directors, the President, any Vice President, if there be one, or the Treasurer,
and  in the  absence  of  the  Treasurer  or in  the  event  of the  Treasurer's
disability or refusal to act,

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<PAGE>



shall perform the duties of the  Treasurer,  and when so acting,  shall have all
the powers of and be  subject to all the  restrictions  upon the  Treasurer.  If
required  by the Board of  Directors,  an  Assistant  Treasurer  shall  give the
Corporation  a bond in such sum and with  such  surety or  sureties  as shall be
satisfactory  to the Board of  Directors  for the  faithful  performance  of the
duties of the  office of  Assistant  Treasurer  and for the  restoration  to the
Corporation, in case of the Assistant Treasurer's death, resignation, retirement
or removal from office, of all books, papers, vouchers, money and other property
of whatever kind in the Assistant Treasurer's  possession or under the Assistant
Treasurer's control belonging to the Corporation.

Section 4.11  Other Officers.

   Such other  officers as the Board of Directors  may choose shall perform such
duties and have such  powers as from time to time may be assigned to them by the
Board of Directors.  The Board of Directors may delegate to any other officer of
the  Corporation  the power to choose such other officers and to prescribe their
respective duties and powers.

                                  ARTICLE V.  STOCK

Section 5.1  Form of Certificates.

   Every  holder  of  stock  in the  Corporation  shall  be  entitled  to have a
certificate  signed,  in the name of the  Corporation (i) by the Chairman of the
Board of Directors,  the President or a Vice President and (ii) by the Treasurer
or an Assistant  Treasurer,  or the  Secretary or an Assistant  Secretary of the
Corporation,  certifying  the number of shares owned by such  stockholder in the
Corporation.

Section 5.2  Signatures.

   Any or all of the signatures on a certificate may be a facsimile. In case any
officer, transfer agent or registrar who has signed or whose facsimile signature
has been  placed  upon a  certificate  shall  have  ceased  to be such  officer,
transfer agent or registrar before such certificate is issued,  it may be issued
by the  Corporation  with the same effect as if such  person were such  officer,
transfer agent or registrar at the date of issue.

Section 5.3  Lost Certificates.

   The Board of Directors may direct a new  certificate to be issued in place of
any certificate theretofore issued by the Corporation alleged to have been lost,
stolen or destroyed,  upon the making of an affidavit of that fact by the person
claiming  the  certificate  of stock  to be  lost,  stolen  or  destroyed.  When
authorizing such issue of a new certificate,  the Board of Directors may, in its
discretion  and as a condition  precedent to the issuance  thereof,  require the
owner of such  lost,  stolen or  destroyed  certificate,  or the  owner's  legal
representative,  to advertise  the same in such manner as the Board of Directors
shall require and/or to give the Corporation a bond in such sum as it may direct
as  indemnity  against any claim that may be made against the  Corporation  with
respect to the certificate alleged to have been lost, stolen or destroyed or the
issuance of such new certificate.

Section 5.4  Transfers.


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<PAGE>



   Stock of the Corporation  shall be  transferable in the manner  prescribed by
law and in these  Bylaws.  Transfers  of stock shall be made on the books of the
Corporation  only by the person  named in the  certificate  or by such  person's
attorney  lawfully  constituted  in  writing  and  upon  the  surrender  of  the
certificate therefor, which shall be cancelled before a new certificate shall be
issued.  No transfer of stock shall be valid as against the  Corporation for any
purpose until it shall have been entered in the stock records of the Corporation
by an entry showing from and to whom transferred.

Section 5.5  Record Date.

   (a) In order that the Corporation may determine the stockholders  entitled to
notice of or to vote at any meeting of stockholders or any adjournment  thereof,
the board of  directors  may fix a record  date,  which  record  date  shall not
precede the date upon which the resolution  fixing the record date is adopted by
the Board of  Directors,  and which record date shall not be more than sixty nor
less than ten days before the date of such  meeting.  If no record date is fixed
by the Board of Directors, the record date for determining stockholders entitled
to notice of or to vote at a meeting  of  stockholders  shall be at the close of
business  on the day next  preceding  the day on which  notice is given,  or, if
notice is waived,  at the close of business on the day next preceding the day on
which the meeting is held. A determination of stockholders of record entitled to
notice of or to vote at a meeting of stockholders shall apply to any adjournment
of the meeting;  providing,  however,  that the Board of Directors may fix a new
record date for the adjourned meeting.

   (b) In order that the Corporation may determine the stockholders  entitled to
consent to corporate action in writing without a meeting, the Board of Directors
may fix a record  date,  which record date shall not precede the date upon which
the resolution fixing the record date is adopted by the Board of Directors,  and
which  record date shall not be more than ten days after the date upon which the
resolution  fixing the record date is adopted by the Board of  Directors.  If no
record  date has been  fixed by the  Board of  Directors,  the  record  date for
determining  stockholders  entitled  to consent to  corporate  action in writing
without a meeting, when no prior action by the Board of Directors is required by
law, shall be the first date on which a signed written consent setting forth the
action taken or proposed to be taken is delivered to the Corporation by delivery
to its registered  office in this State, its principal place of business,  or an
officer  or  agent  of the  Corporation  having  custody  of the  book in  which
proceedings  of  meetings  of  stockholders  are  recorded.  Delivery  made to a
corporation's  registered  office shall be by hand or by certified or registered
mail, return receipt requested. If no record date has been fixed by the Board of
Directors  and prior  action by the Board of  Directors  is required by law, the
record date for determining stockholders entitled to consent to corporate action
in writing  without a meeting  shall be at the close of  business  on the day on
which the Board of Directors adopts the resolutions taking such prior action.

   (c) In order that the Corporation may determine the stockholders  entitled to
receive payment of any dividend or other distribution or allotment of any rights
or the  stockholders  entitled to exercise  any rights in respect of any change,
conversion or exchange of stock,  or for the purpose of any other lawful action,
the Board of  Directors  may fix a record  date,  which  record  date  shall not
precede  the date upon which the  resolution  fixing the record date is adopted,
and which record date shall be not more than sixty days prior to such action. If
no record date is fixed,  the record date for determining  stockholders  for any
such purpose  shall be at the close of business on the day on which the Board of
Directors adopts the resolution relating thereto.

Section 5.6 Record Owners.

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<PAGE>




   The  Corporation  shall be entitled to  recognize  the  exclusive  right of a
person registered on its books as the owner of shares to receive dividends,  and
to vote as such  owner,  and to hold liable for calls and  assessments  a person
registered  on its  books as the  owner of  shares,  and  shall  not be bound to
recognize any equitable or other claim to or interest in such share or shares on
the part of any other  person,  whether  or not it shall  have  express or other
notice thereof, except as otherwise required by law.

                                ARTICLE VI.  NOTICES

Section 6.1 Notices.

   Whenever  written notice is required by law, the Certificate of Incorporation
or  these  Bylaws,  to be  given  to any  director,  member  of a  committee  or
stockholder,  such  notice  may be given by mail,  addressed  to such  director,
member of a committee or stockholder,  at such person's address as it appears on
the records of the Corporation,  with postage thereon  prepaid,  and such notice
shall be deemed to be given at the time when the same shall be  deposited in the
United States mail.  Written notice may also be given personally or by telegram,
telex or cable.

Section 6.2 Waivers of Notice.

   Whenever any notice is required by law, the Certificate of  Incorporation  or
these Bylaws, to be given to any director, member of a committee or stockholder,
a waiver thereof in writing,  signed,  by the person or persons entitled to said
notice,  whether  before  or after  the time  stated  therein,  shall be  deemed
equivalent  thereto.  Attendance of a person at a meeting,  present in person or
represented  by proxy,  shall  constitute  a waiver  of notice of such  meeting,
except where the person attends the meeting for the express purpose of objecting
at the beginning of the meeting to the  transaction of any business  because the
meeting is not lawfully called or convened.

                          ARTICLE VII.  GENERAL PROVISIONS

Section 7.1 Dividends.

   Dividends  upon  the  capital  stock  of  the  Corporation,  subject  to  the
requirements of the DGCL and the provisions of the Certificate of Incorporation,
if any,  may be  declared  by the Board of  Directors  at any regular or special
meeting of the Board of  Directors  (or any  action by  written  consent in lieu
thereof  in  accordance  with  Section 3.6 hereof),  and may be paid  in  cash,
in
property, or in shares of the Corporation's capital stock. Before payment of any
dividend,  there may be set aside out of any funds of the Corporation  available
for dividends  such sum or sums as the Board of Directors  from time to time, in
its  absolute  discretion,  deems  proper  as a  reserve  or  reserves  to  meet
contingencies,  or for equalizing dividends, or for repairing or maintaining any
property  of the  Corporation,  or for any  proper  purpose,  and the  Board  of
Directors may modify or abolish any such reserve.

Section 7.2 Disbursements.

   All checks or demands for money and notes of the Corporation  shall be signed
by such  officer or  officers  or such  other  person or persons as the Board of
Directors may from time to time designate.


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<PAGE>



Section 7.3 Fiscal Year.

   The fiscal year of the Corporation  shall be fixed by resolution of the Board
of Directors.

Section 7.4 Corporate Seal.

   The corporate seal shall have inscribed  thereon the name of the Corporation,
the year of its organization and the words "Corporate Seal, Delaware".  The seal
may be used by causing it or a facsimile  thereof to be  impressed or affixed or
reproduced or otherwise.

                           ARTICLE VIII.  INDEMNIFICATION

Section 8.1  Power to Indemnify in Actions, Suits or Proceedings other than
             those by or in the Right of the Corporation.

Subject to Section 8.3, the Corporation shall indemnify any person who was or is
a party  or is  threatened  to be made a party  to any  threatened,  pending  or
completed action, suit or proceeding, whether civil, criminal, administrative or
investigative  (other than an action by or in the right of the  Corporation)  by
reason of the fact  that such  person is or was a  director  or  officer  of the
Corporation,  or is or was a director or officer of the  Corporation  serving at
the request of the  Corporation  as a director or officer,  employee or agent of
another corporation, partnership, joint venture, trust, employee benefit plan or
other enterprise, against expenses (including attorneys' fees), judgments, fines
and amounts paid in settlement  actually and reasonably  incurred by such person
in connection with such action,  suit or proceeding if such person acted in good
faith and in a manner such person reasonably believed to be in or not opposed to
the best interests of the Corporation,  and, with respect to any criminal action
or  proceeding,  had no reasonable  cause to believe such  person's  conduct was
unlawful. The termination of any action, suit or proceeding by judgment,  order,
settlement,  conviction,  or upon a plea of nolo  contendere or its  equivalent,
shall not, of itself,  create a presumption  that the person did not act in good
faith and in a manner  which such  person  reasonably  believed  to be in or not
opposed to the best  interests  of the  Corporation,  and,  with  respect to any
criminal  action  or  proceeding,  had  reasonable  cause to  believe  that such
person's conduct was unlawful.

Section 8.2 Power to Indemnify  in Actions,  Suits or  Proceedings  by or in the
Right of the Corporation.

Subject to Section 8.3, the Corporation shall indemnify any person who was or is
a party  or is  threatened  to be made a party  to any  threatened,  pending  or
completed  action or suit by or in the  right of the  Corporation  to  procure a
judgment  in its  favor by  reason  of the fact  that  such  person  is or was a
director  or officer of the  Corporation,  or is or was a director or officer of
the  Corporation  serving  at the  request  of the  Corporation  as a  director,
officer, employee or agent of another corporation,  partnership,  joint venture,
trust,  employee  benefit plan or other enterprise  against expenses  (including
attorneys'  fees) actually and reasonably  incurred by such person in connection
with the defense or  settlement  of such action or suit if such person  acted in
good  faith and in a manner  such  person  reasonably  believed  to be in or not
opposed to the best interests of the Corporation; except that no indemnification
shall be made in respect of any claim,  issue or matter as to which such  person
shall have been adjudged to be liable to the Corporation  unless and only to the
extent  that the Court of Chancery or the court in which such action or suit was
brought shall  determine upon  application  that,  despite the  adjudication  of
liability but in view of all the circumstances of the case, such

                                         12

<PAGE>



person is fairly and  reasonably  entitled to indemnity for such expenses  which
the Court of Chancery or such other court shall deem proper.

Section 8.3 Authorization of Indemnification.

     Any  indemnification  under this Article VIII (unless  ordered by a court)
shall be
made by the  Corporation  only as  authorized  in the specific  case upon a
determination that  indemnification of the director or officer is proper in
the  circumstances  because such person has met the applicable  standard of
conduct  set  forth  in  Section 8.1 or 8.2 hereof,  as the  case  may  be.
Such
determination  shall be made, with respect to a person who is a director or
officer at the time of such  determination,  (i) by a majority  vote of the
directors  who are not parties to such  action,  suit or  proceeding,  even
though  less  than a  quorum,  or (ii)  by a  committee  of such  directors
designated  by a majority vote of such  directors,  even though less than a
quorum,  or (iii) if there are no such  directors,  or if such directors so
direct,  by independent  legal counsel in a written  opinion or (iv) by the
stockholders.  Such  determination  shall be made,  with  respect to former
directors  and officers,  by any person or persons  having the authority to
act on the matter on behalf of the  Corporation.  To the  extent,  however,
that a present or former  director or officer of the  Corporation  has been
successful  on the merits or  otherwise  in defense of any action,  suit or
proceeding  described  above,  or in defense of any claim,  issue or matter
therein,  such person  shall be  indemnified  against  expenses  (including
attorneys'  fees)  actually  and  reasonably  incurred  by such  person  in
connection  therewith,  without  the  necessity  of  authorization  in  the
specific case.

Section 8.4 Good Faith Defined.

For purposes of any determination under Section 8.3, a person shall be deemed to
have acted in good faith and in a manner such person  reasonably  believed to be
in or not opposed to the best interests of the Corporation,  or, with respect to
any criminal  action or proceeding,  to have had no reasonable  cause to believe
such  person's  conduct was unlawful,  if such  person's  action is based on the
records or books of  account of the  Corporation  or another  enterprise,  or on
information  supplied  to such  person by the  officers  of the  Corporation  or
another  enterprise  in the  course of their  duties,  or on the advice of legal
counsel for the  Corporation or another  enterprise or on information or records
given or reports made to the Corporation or another enterprise by an independent
certified  public  accountant  or by an appraiser or other expert  selected with
reasonable  care by the  Corporation  or another  enterprise.  The term "another
enterprise"  as used in this  Section  shall mean any other  corporation  or any
partnership,  joint venture, trust, employee benefit plan or other enterprise of
which such  person is or was  serving at the  request  of the  Corporation  as a
director,  officer,  employee or agent. The provisions of this Section 8.4 shall
not
be deemed to be  exclusive or to limit in any way the  circumstances  in which a
person may be deemed to have met the applicable standard of conduct set forth in
Section 8.1 or 8.2, as the case may be.

Section 8.5 Indemnification by a Court.

Notwithstanding any contrary  determination in the specific case under
Section  8.3,  and   notwithstanding   the  absence  of  any  determination
thereunder  any  director  or officer may apply to the Court of Chancery in
the  State  of  Delaware  for   indemnification  to  the  extent  otherwise
permissible  under  Sections  8.1  and  8.2  hereof.   The  basis  of  such
indemnification  by a court  shall be a  determination  by such  court that
indemnification  of the director or officer is proper in the  circumstances
because such person has met the  applicable  standards of conduct set forth
in Section 8.1 or 8.2 hereof, as the case may be. Neither a contrary

                                         13

<PAGE>



determination  in the  specific  case  under  Section  8.3 nor the  absence
of any
determination  thereunder  shall be a defense  to such  application  or create a
presumption that the director or officer seeking indemnification has not met any
applicable  standard of conduct.  Notice of any application for  indemnification
pursuant to this Section 8.5 shall be given to the  Corporation  promptly  upon
the
filing of such application.  If successful, in whole or in part, the director or
officer seeking indemnification shall also be entitled to be paid the expense of
prosecuting such application.

Section 8.6 Expenses Payable in Advance.

   Expenses incurred by a director or officer in defending any civil,  criminal,
administrative or investigative  action, suit or proceeding shall be paid by the
Corporation  in  advance  of the  final  disposition  of  such  action,  suit or
proceeding  upon receipt of an  undertaking  by or on behalf of such director or
officer to repay such  amount if it shall  ultimately  be  determined  that such
person is not entitled to be  indemnified  by the  Corporation  as authorized in
this Article VIII.

Section 8.7 Nonexclusivity of Indemnification and Advancement of Expenses.

   The  indemnification  and  advancement  of  expenses  provided  by or granted
pursuant  to this  shall not be deemed  exclusive  of any other  rights to which
those seeking  indemnification  or advancement of expenses may be entitled under
the Certificate of Incorporation,  any Bylaw, agreement, vote of stockholders or
disinterested  directors  or  otherwise,  both as to  action  in  such  person's
official  capacity  and as to action in  another  capacity  while  holding  such
office,  it being the  policy of the  Corporation  that  indemnification  of the
persons  specified in Sections 8.1 and 8.2 hereof  shall be made to the fullest
extent
permitted  by law.  The  provisions  of this shall not be deemed to preclude the
indemnification  of any person who is not  specified  in Section 8.1 or 8.2 but
whom the
Corporation has the power or obligation to indemnify under the provisions of the
General Corporation Law of the State of Delaware, or otherwise.

Section 8.8 Insurance.

   The Corporation  may purchase and maintain  insurance on behalf of any person
who is or was a director or officer of the Corporation,  or is or was a director
or officer of the  Corporation  serving at the request of the  Corporation  as a
director, officer, employee or agent of another corporation,  partnership, joint
venture,  trust, employee benefit plan or other enterprise against any liability
asserted  against such person and incurred by such person in any such  capacity,
or arising out of such person's  status as such,  whether or not the Corporation
would have the power or the  obligation  to indemnify  such person  against such
liability under the provisions of this Article VIII.

Section 8.9 Certain Definitions.

     For purposes of this Article  VIII,  references  to "the  Corporation"
shall include,  in addition to the resulting  corporation,  any constituent
corporation  (including any  constituent  of a  constituent)  absorbed in a
consolidation  or merger which,  if its separate  existence had  continued,
would have had power and  authority to indemnify its directors or officers,
so that any person who is or was a director or officer of such  constituent
corporation,  or is or  was a  director  or  officer  of  such  constituent
corporation  serving at the request of such  constituent  corporation  as a
director,  officer, employee or agent of another corporation,  partnership,
joint venture,  trust,  employee  benefit plan or other  enterprise,  shall
stand in the same position under the provisions

                                         14

<PAGE>



of this Article VIII with respect to the resulting or surviving corporation
as such
person  would have with  respect  to such  constituent  corporation  if its
separate  existence  had  continued.  For  purposes of this  Article  VIII,
references to "fines"  shall include any excise taxes  assessed on a person
with respect to an employee benefit plan; and references to "serving at the
request of the  Corporation"  shall  include  any  service  as a  director,
officer,  employee or agent of the Corporation  which imposes duties on, or
involves  services by, such director or officer with respect to an employee
benefit plan, its participants or beneficiaries;  and a person who acted in
good faith and in a manner  such  person  reasonably  believed to be in the
interest of the participants and  beneficiaries of an employee benefit plan
shall  be  deemed  to have  acted  in a  manner  "not  opposed  to the best
interests of the Corporation" as referred to in this Article VIII.

Section 8.10 Survival of Indemnification and Advancement of Expenses.

   The  indemnification  and  advancement  of expenses  provided  by, or granted
pursuant to, this shall,  unless otherwise provided when authorized or ratified,
continue  as to a person who has ceased to be a  director  or officer  and shall
inure to the  benefit  of the  heirs,  executors  and  administrators  of such a
person.

Section 8.11 Limitation on Indemnification.

   Notwithstanding  anything  contained  in this Article VIII to the  contrary,
except  for
proceedings  to enforce  rights to  indemnification  (which shall be governed by
Section 8.5 hereof),  the  Corporation  shall not be  obligated  to  indemnify
any
director or officer in connection with a proceeding (or part thereof)  initiated
by such person  unless such  proceeding  (or part  thereof)  was  authorized  or
consented to by the Board of Directors of the Corporation.

Section 8.12 Indemnification of Employees and Agents.

   The Corporation may, to the extent  authorized from time to time by the Board
of  Directors,  provide  rights to  indemnification  and to the  advancement  of
expenses to employees and agents of the  Corporation  similar to those conferred
in this Article VIII to directors and officers of the Corporation.

                               ARTICLE IX.  AMENDMENTS

Section 9.1 Amendments.

   These Bylaws may be altered, amended or repealed, in whole or in part, or new
Bylaws  may  be  adopted  by the  stockholders  or by the  Board  of  Directors,
provided, however, that notice of such alteration, amendment, repeal or adoption
of new Bylaws be  contained  in the notice of such  meeting of  stockholders  or
Board of Directors as the case may be. All such  amendments  must be approved by
either the holders of a majority of the  outstanding  capital stock  entitled to
vote thereon or by a majority of the entire Board of Directors then in office.

Section 9.2 Entire Board of Directors.

   As used in this Article IX and in these  Bylaws  generally,  the term
"entire  Board of
Directors" means the total number of directors which the Corporation  would have
if there were no vacancies.

                                         15

<PAGE>




Adopted as of the 1st day of March, 1999


                                         16




                  NOT VALID UNLESS COUNTERSIGNED BY TRANSFER AGENT
                       INCORPORATED UNDER THE LAWS OF DELAWARE



                                  Advanced Business
                                   Sciences, Inc.

                       AUTHORIZED CAPITAL STOCK:  $50,000,000
                                   $.001 PAR VALUE
                                                                      688-797800
                                             SEE REVERSE FOR CERTAIN DEFINITIONS





   THIS CERTIFIES THAT  _______________________________________________________
holder of                           Shares of   ADVANCED BUSINESS SCIENCES, INC.
          -------------------------

transferable only on the books of the Corporation by the holder hereof in person
or by Attorney upon surrender of this Certificate properly endorsed.

   In Witness  Whereof,  the said  Corporation has caused this Certificate to be
signed by its duly  authorized  officers and its  Corporate  Seal to be hereunto
affixed.

Dated:



   Secretary                                    President

                                                    COUNTERSIGNED AND REGISTERED

                                               BY
                                                            AUTHORIZED SIGNATURE





<PAGE>



The following  abbreviations,  when used in the  inscription on the face of this
certificate,  shall  be  construed  as  though  they  were  written  out in full
according to applicable laws or regulations:

   TEN COM - as tenants in common   UNIF GIFT MIN ACT -- . . . . .  Custodian --
 .

   TEN ENT - as tenants by the entireties     (Cust)  (Minor)

   JT TEN -   as joint tenants with right of survivorship under Uniform Gifts to
             Minors survivorship and not as tenants
             Act . . . . . .
         in common                                (State)

       Additional abbreviations may also be used though not in the above list.

   For Value Received,              hereby sell, assign and transfer unto

PLEASE INSERT SOCIAL SECURITY OR OTHER
     IDENTIFYING NUMBER OF ASSIGNEE


- ------------------------------------------




- ------------------------------------------------------------------------------

   (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE)

- ------------------------------------------------------------------------------
- ------------------------------------------------------------------------------



- ------------------------------------------------------------------------------


          Shares of the capital stock represented by the within Certificate, and
     do hereby irrevocably constitute and appoint

___________________________  Attorney
to transfer  the said stock on the books of the within  named  Corporation  with
full power of substitution in the premises.

Dated


Signature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
                                 NOTICE:  The signature in this  assignment must
                                 correspond  with the name as  written  upon the
                                 face of the Certificate,  in every  particular,
                                 without  alteration  or  enlargement,   or  any
                                 change whatever.


Signature Guaranteed By: . . . . . . . . . . . . . . . . . . . . . . . . . . . .
                           (Please have signature  guaranteed by a National Bank
                           through  its  officer or by a member  firm of a major
                           stock exchange)







BUSINESS PROPERTY LEASE
THIS  LEASE is  entered  into this  30th dav of  November,  1998,  between F & J
Enterprises, Inc., Landlord, and Advanced Business Sciences, Inc., Tenant.

PREMISES
1. Landlord  leases to Tenant 3343,  3345 and.3347  North 107 1h Street,  Omaha,
Nebraska,  68134 - as  outlined in red on  attached  Exhibit "A" Omaha,  Douglas
County,  Nebraska, (the "Premises"),  containing approximately 6,212 square feet
of area, on the following terms and conditions.

TERM
2. This Lease shall be for a term of Three (3) years, beginning on the I" day of
December,  1998 and ending on the 30th day of November,  2001, unless terminated
earlier as provided in this Lease.

If for any reason the  Premises  are  delivered  to Tenant on any date before or
after the,  term  commencement  day,  rental for the period  between the date of
possession and the term commencement date shall be adjusted on a pro rata basis.
Such earlier or later taking of possession shall not change the termination date
of this  Lease.  This Lease shall not be void or voidable in the event of a late
delivery by Landlord,  nor shall  Landlord be liable to Tenant for any resulting
loss or damage.

USE OF PREMISES
3. The  Premises  are  leased to Tenant,  and are to be used by Tenant,  for the
purposes of office, sales and service of semi-conductor/GPS Systems and no other
purpose.  Tenant agrees to use the Premises in such a manner as to not interfere
with  the  right  of  other  tenants  in the Real  Estate,  to  comply  with all
applicable governmental laws, ordinances, and regulations in connection with its
use of the Premises, to keep the Premises in a clean and sanitary condition,  to
keep the Premises and all sidewalks and  approaches  thereto in a safe condition
free and clear of ice and snow and all other  matter  which may be  dangerous to
the public and free of all obstructions, and to use all reasonable precaution to
prevent waste, damage, or injury to the Premises.

RENT
4. (a) Base Rent.  The total Base Rent  under  this Lease is One  Hundred  Sixty
Seven  Thousand  Seven Hundred  Twenty-Four  and no/100  Dollars  ($167,724.00).
Tenant  agrees  to pay rent to  Landlord  at 3323  North  107'h  Street,  Omaha,
Nebraska  68134,  or at any other place  Landlord may  designate in writing,  in
lawful money of the United States,  in monthly  installments in advance,  on the
first day of each month, as follows:

For the period from December 1, 1998 to November 30, 2001, $4,659.00 per month.

(b)  Operating  Expenses.  In addition to the Base Rent,  Tenant shall pay a pro
rata share of  operating  expenses of the real estate of which the  Premises are
part,  parking areas,  and grounds ("Real Estate").  "Operating  expenses" shall
mean all costs of maintaining  and operating the Real Estate,  including but not
limited  to all taxes  and  special  assessments  levied  upon the Real  Estate,
fixtures,  and  personal  property  used by  Landlord  at the Real  Estate,  all
insurance  costs,  all costs of labor,  material and  supplies for  maintenance,
repair, replacement, and operation of the Real Estate, including but not limited
to line painting, lighting, snow removal, landscaping, cleaning, depreciation of
machinery and equipment used in such  maintenance,  repair and replacement,  and
management costs including  building  superintendents.  Operating Expenses shall
not include  property  additions  and capital  improvements  to the real estate,
alterations  made for specific  tenants,  depreciation of the Real Estate,  debt
service on long-term debt or income taxes paid by Landlord.



<PAGE>



"Tenant's pro rata share" shall mean the  percentage  determined by dividing the
square feel of the  Premises as shown in Paragraph 1 by the square feet of store
area of the Real Estate, as defined by the American National Standard  published
by Building Owners and Managers Association,  which at the date hereof is agreed
to be 30,074 square feet.

Tenant's pro rata share of the  Operating  Expenses  shall be  determined  on an
annual basis for each  calendar year ending on December 31 and shall be prorated
for the number of months  Tenant  occupied the Premises if Tenant did not occupy
the Premises the full year. Tenant shall pay One Thousand Ninety-Nine and 53/100
Dollars  ($1099.53)  per month,  on the first of each month in advance with rent
for Tenant's  estimated pro rata share of the Operating  Expenses.  Landlord may
change this amount at any time upon written notice to Tenant. At the end of each
year, an analysis of the total year's  Operating  Expenses shall be presented to
Tenant and Tenant  shall pay the amount,  if any, by which the Tenant's pro rata
share  of the  Operating  Expenses  for the  year  exceeded  the  amount  of the
Operating  Expenses  paid by Tenant.  Tenant shall pay any such excess charge to
the Landlord within thirty (30) days after receiving the statement. In the event
this  lease  terminates  at any time  other  than the last day of the year,  the
excess  Operating  Expenses  shall be determined as of the date of  termination.
Upon termination of this Lease, any overpayment of Operating  Expenses by Tenant
shall be applied to the amounts due  Landlord  from Tenant  under this Lease and
any remaining overpayment shall be refunded to Tenant.

(c)  Payment  of  Rent.  Tenant  agrees  to pay the Base  Rent as and when  due,
together  with Tenant's  share of the  Operating  Expenses and all other amounts
required to be paid by Tenant under this Lease.  In the event of  nonpayment  of
any amounts due under this Lease,  whether or not  designated as rent,  Landlord
shall  have all the  rights and  remedies  provided  in this Lease or by law for
failure to pay rent.

(d) Late  Charge.  If the Tenant  fails to pay the Base Rent  together  with the
Tenant's  share of the Operating  Expenses and all other amounts  required to be
paid by Tenant under this Lease,  on or before the third day after such payments
are due,  Tenant  agrees to pay  Landlord a late charge of Ten (10%)  Percent of
Total Base Rent and Operating Expenses.

(e) Security Deposit. As partial  consideration for the execution of this Lease,
the Tenant has  delivered to Landlord the sum of $5,758.53 as Security  Deposit.
The Security  Deposit will be returned to Tenant at the expiration of this Lease
if Tenant has fully complied with all covenants and conditions of this Lease.

SERVICES
 Landlord shall furnish electricity,  Sewer, Water and Gas Lines to the Premises
at Landlord's Expense.  Tenant shall be responsible for payment of all bills for
utilities to the Premises during normal business hours,  and at such other times
as Landlord may deem necessary or desirable, in the manner customary to the Real
Estate.  Landlord  shall have the right to  discontinue  any service  during any
period for which rent is not  promptly  paid by  Tenant.  Landlord  shall not be
liable for damages,  nor shall the rental be abated, for failure to furnish,  or
delay  in  furnishing,  any  service  when  failure  to  furnish,  or  delay  in
furnishing,  is occasioned in whole or in part by needful repairs,  renewals, or
improvements,  or by any  strike or labor  controversy,  or by any  accident  or
casualty  whatsoever,  or by any  unauthorized act or default of any employee of
Landlord,  or for any other  cause or causes  beyond the  control  of  Landlord.
Tenant shall pay when due, all water, gas, electricity, sewer use fees, incurred
at or chargeable to the Premises.



<PAGE>




ASIGNMENT OR SUBLEASE
6.  Tenant  shall not  assign  this Lease or sublet the whole or any part of the
Premises,  transfer this Lease by operation of law or  otherwise,  or permit any
other person except  agents and  employees of Tenant to occupy the Premises,  or
any part thereof,  without the prior written  consent of Landlord.  Landlord may
consider the following in determining whether to withhold consent: (a) financial
responsibility of the new tenant, (b) identity and business character of the new
tenant, (c) nature and legality of the proposed use of the Premises.

Landlord  shall  have the right to assign its  interest  under this Lease or the
rent reserved hereunder.

TENANT'S IMPROVEMENTS
7.  Tenant  shall  have the  right to place  partitions  and  fixtures  and make
improvements  or other  alterations  in the  interior of the Premises at its own
expense.  Prior to  commencing  any such work,  Tenant  shall  first  obtain the
written consent of Landlord for the proposed work.  Landlord may, as a condition
to its consent, require that the work be done by Landlord's own employees and/or
under Landlord's supervision, but at the expense of Tenant, and that Tenant give
sufficient  security that the Premises will be completed free and clear of liens
and in a manner  satisfactory  to Landlord.  Upon  termination of this Lease, at
Landlord's  option,  Tenant will  repair and restore the  Premises to its former
condition,  at  Tenant's  expense,  or  any  such  improvements,  additions,  or
alteration  installed or made by Tenant,  except  Tenant's trade fixtures at the
termination  of tie Lease  provided  Tenant is not then in default  and  provide
further that Tenant repairs any damage cause by such removal.

REPAIRS
8. Landlord  agrees to maintain in good  condition,  and repair as necessary the
foundations,  exterior walls and the roof of the Premises. Tenant agrees that it
will make,  at its own cost and  expense,  all repairs and  replacements  to the
Premises not required to be made by Landlord, including, but not limited to, all
interior and exterior doors, door frames, windows, plate glass, and the heating,
air conditioning, plumbing and electrical systems servicing the Premises. Tenant
agrees to do all redecorating,  remodeling, alteration, and painting required by
it  during  the term of the  Lease at its own cost and  expense,  to pay for any
repairs to the Premises or the Real Estate made  necessary by any  negligence or
carelessness of Tenant or any of its agents or employees or persons permitted on
the Real Estate by Tenant,  and to maintain the Premises in a safe, clean, neat,
and  sanitary  condition.  Tenant  shall  be  entitled  to no  compensation  for
inconvenience,  injury,  or loss of  business  arising  from the  making  of any
repairs  by  Landlord,  Tenant,  or other  tenants to the  premises  or the Real
Estate.

CONDITION OF PREMISES
9. Except as provided herein,  Tenant agrees that no promises,  representations,
statements  or  warranties  have  been  made on  behalf  of  Landlord  to Tenant
respecting  the condition of the  Premises,  or the manner of operating the Real
Estate,  or the making of any repairs to the Premises.  By taking  possession of
the  Premises,   Tenant   acknowledges  that  the  Premises  were  in  good  and
satisfactory   condition  when  possession  was  taken.  Tenant  shall,  at  the
termination of this Lease, by lapse of time or otherwise, remove all of Tenant's
property and  surrender  the  Premises to Landlord in as good  condition as when
Tenant took possession, normal wear excepted.



<PAGE>



PERSONAL PROPERTY AT RISK OF TENANT
10. All personal  property in the Premises  shall be at the risk of Tenant only.
Landlord  shall not be liable  for any damage to any  property  of Tenant or its
agents or employees in the Premises caused by steam, electricity, sewage, gas or
odors, or from water,  rain, or snow which may leak into, issue or flow into the
Premises from any part of the Real Estate,  or from any other place,  or for any
damage  done to  Tenant's  property in moving same to or from the Real Estate or
the Premises.  Tenant shall give Landlord,  or its agents, prompt written notice
of any damage to or defects in water pipes, gas or warming or cooling  apparatus
in the Premises.

LANDLORD'S RESERVED RIGHTS

11. Without notice to Tenant,  without  liability to Tenant for damage or injury
to property, person, or business, and without effecting an eviction of Tenant or
a  disturbance  of Tenant's  use or  possession  or giving rise to any claim for
setoff or abatement of rent, Landlord shall have the right to:

   Change the name or street  address of the Real  Estate.  Install and maintain
   signs on the exterior of the Real Estate.
   Have access to all mail  chutes  according  to the rules of the United  Sates
   Post Office Department. At reasonable times, to decorate, and to make, at its
   own expense, repairs, alterations, additions, and
improvements structural or otherwise, in or to the Premises, the Real Estate, or
part thereof, and any adjacent building, land, street, or alley, and during such
operations  to take into and through the Premises or any part of the Real Estate
all  materials  required,  and to  temporarily  close or  suspend  operation  of
entrances,  doors,  corridors,  elevators,  or other  facilities  to do so.  (e)
Possess passkeys to the Premises.  (f) Show the Premises to prospective  tenants
at  reasonable  times.  (g)  Take  any and all  reasonable  measures,  including
inspections   or  the  making  of  repairs,   alterations,   and  additions  and
improvements  to the  Premises  or to the  Real  Estate,  which  Landlord  deems
necessary or desirable for the safety, protection, operation, or preservation of
the  Premises or the Real  Estate.  (h) Approve  all sources  furnishing  signs,
painting,  and/or  lettering  to the  Premises,  and  approve  all  signs on the
Premises prior to installation thereof.

INSURANCE
12.  Tenant  shall not use or occupy  the  premises  or any part  thereof in any
manner which could  invalidate any policies of insurance now or hereafter placed
on the real estate or increase the risks covered by insurance on the real estate
or necessitate  additional insurance premiums or policies of insurance,  even if
such use may be in furtherance of tenant's business  purposes.  In the event any
policies of insurance are  invalidated by acts or omissions of tenant,  landlord
shall have the right to terminate this lease or, at landlord's option, to charge
tenant for extra  insurance  premiums  required on the real estate on account of
the increased  risk caused by tenant's use and  occupancy of the premises.  Each
party  hereby  waives  all claims  for  recovery  from the other for any loss or
damage to any of its  property  insured  under valid and  collectible  insurance
policies  to the  extent  of  any  recovery  collectible  under  such  policies.
Provided,  that this waiver shall apply only when  permitted  by the  applicable
policy of insurance.

INDEMNITY
13. Tenant shall indemnify, hold harmless, and defend Landlord from and against,
and  Landlord  shall not be liable to Tenant on  account  of, any and all costs,
expenses,  liabilities,  losses,  damages,  suits,  actions,  fines,  penalties,
demands, or claims of any kind, including  reasonable  attorney's fees, asserted
by or on behalf of any person,  entity, or governmental authority arising out of
or in any way  connected  with  either (a) a failure by Tenant to perform any of
the  agreements,  terms or conditions of this Lease  required to be performed by
Tenant; (b) a failure by Tenant to comply with any laws,  statutes,  ordinances,
regulations


<PAGE>



or order of any governmental authority; or (c) any accident,  death, or personal
injury, or damage to, or loss or theft of property which shall occur on or about
the  Premises,  or the Real Estate,  except as the same may be the result of the
negligence of Landlord, its employees, or agents.

LIABILITY INSURANCE
14. Tenant agrees to procure and maintain continuously during the entire term of
this  Lease,  a policy  or  policies  of  insurance  in a company  or  companies
acceptable to Landlord, at Tenant's own cost and expense,  insuring Landlord and
Tenant from all claims,  demands or actions; such comprehensive  insurance shall
protect  and name the Tenant as the  Insured  and shall  provide  coverage of at
least  $1,000,000.00 for injuries to any one person,  $2,000,000.00 for injuries
to persons in any one accident and $1,000,000.00 for damage to property, made by
or on behalf of any person or persons, firm or corporation arising from, related
to, or  connected  with the conduct and  operation  of Tenant's  business in the
Premises,  or  arising  out of and  connected  with  the  use and  occupancy  of
sidewalks and other Common Areas by the Tenant. All such insurance shall provide
that the  Landlord  shall be given a  minimum  of ten (10)  days  notice  by the
insurance  company  prior  to  cancellation,   termination  or  change  of  such
insurance.  Tenant  shall  provide  Landlord  with  copies  of the  policies  or
certificates  evidencing  that such  insurance  is in full  force and effect and
stating the term and  provisions  thereof.  If Tenant  fails to comply with such
requirements  for insurance,  Landlord may, but shall not be obligated to obtain
such  insurance and keep the same in effect,  and Tenant agrees to pay Landlord,
upon demand, the premium cost thereof.

DAMAGE BY FIRE OR OTHER CASUALTY
15. If, during the term of this Lease,  the Premises shall be so damaged by fire
or any other cause except Tenant's  negligent or intentional act so as to render
the Premises  untenantable,  the rent shall be abated while the Premises  remain
untenantable;  and in the event of such damage,  Landlord shall elect whether to
repair the Premises or to cancel this Lease,  and shall notify Tenant in writing
of its election within sixty (60) days after such damage.  In the event Landlord
elects to repair the Premise,  the work or repair shall begin promptly and shall
be carried on without  unnecessary  delay.  In the event Landlord  elects not to
repair the Premises,  the Lease shall be deemed  cancelled as of the date of the
damage. Such damage shall not extend the Lease term.

CONDEMNATION
16. If the whole or any part of the Premises shall be taken by public  authority
under the power of eminent  domain,  then the term of this Lease  shall cease on
that portion of the Premises so taken, from the date of possession, and the rent
shall be paid to that date, with a proportionate refund by Landlord to Tenant of
such rent as may have been paid by Tenant  in  advance.  If the  portion  of the
Premises  taken is such that it prevents the  practical  use of the Premises for
Tenant's purposes, then Tenant shall have the right either (a) to terminate this
Lease by giving  written  notice of such  termination to Landlord not later than
thirty (30) days after the  taking;  or (b) to  continue  in  possession  of the
remainder of the  Premises,  except that the rent shall be reduced in proportion
to the area of the Premises taken. In the event of any taking or condemnation of
the Premises,  in whole or in part, the entire  resulting award of damages shall
be the  exclusive  property  of  Landlord,  including  all  damages  awarded  as
compensation for diminution in value to the leasehold, without any deduction for
the  value of any  unexpired  term of this  Lease,  or for any  other  estate or
interest in the Premises now or hereafter vested in Tenant.

DEFAULT OR BREACH
   Each of the following  events shall  constitute a default or a breach of this
Lease by Tenant:

      In Tenant fails to pay Landlord any rent or additional when due hereunder;
      If Tenant vacates or abandons the Premises;


<PAGE>



      If  Tenant  files  a  petition  in   bankruptcy   or   insolvency  or  for
reorganization  under any bankruptcy act, or voluntarily  takes advantage of any
such act by answer or  otherwise,  or makes an  assignment  for the  benefits of
creditors;
      If involuntary proceedings under any bankruptcy or insolvency act shall be
instituted against Tenant, or if a receiver or trustee shall be appointed of all
or substantially  all of the property of Tenant,  and such proceedings shall not
be dismissed or the receivership or trusteeship  vacated within thirty (30) days
after the institution or appointment; or

      If Tenant  fails to perform or comply with any other term or  condition of
this Lease and if such  nonperformance  shall  continue for a period of ten (10)
days after notice thereof by Landlord to Tenant, time being of the essence.



<PAGE>




EFFECT OF DEFAULT
   In the event of any  default or breach  hereunder,  in  addition to any other
right or remedy available to Landlord,  either at law or in equity, Landlord may
exert, any one or more of the following rights:

      Landlord may re-enter the Premises immediately and remove the property and
personnel of Tenant,  and shall have the right,  but not the obligation to store
such property in a public  warehouse or at a place selected by Landlord,  at the
risk and expense of Tenant.

      Landlord may retake the Premises  and may  terminate  this Lease by giving
written  notice of  termination  to  Tenant.  Without  such  notice,  Landlord's
retaking will not terminate the Lease. On termination, Landlord may recover from
Tenant all damages proximately resulting from the breach,  including the cost of
recovering the Premises and the difference  between the rent due for the balance
of the  Lease  term,  as  though  the  Lease  had not been  terminated,  and the
reasonable  rental value of the  Premises,  which sum shall be  immediately  due
Landlord from Tenant.

      Landlord  may relet the  Premises or any part thereof for any term without
terminating  this  Lease,  at such  rent  and on such  terms  as it may  choose.
Landlord  may make  alternations  and  repairs to the  Premises.  In addition to
Tenant's liability to Landlord for breach of this lease,  Tenant shall be liable
for all expenses of the reletting, for any alterations and repairs made, and for
the rent due for the balance of the lease term,  which sum shall be  immediately
due  Landlord  from Tenant.  The amount due Landlord  will be reduced by the net
rent received by Landlord during the remaining term of this Lease from reletting
the Premises or any part  thereof.  If during the  remaining  term of this Lease
Landlord receives more than the amount due Landlord under this subparagraph, the
Landlord  shall pay such  excess to Tenant,  but only to the  extent  Tenant has
actually made 1,i, payment pursuant to this sub-paragraph.

SURRENDER - HOLDING OVER
19. Tenant shall,  upon  termination of this Lease,  whether by lapse of time or
otherwise,  peaceably and promptly surrender the Premises to Landlord. If Tenant
remains in possession after the termination of this Lease, without written Lease
duly  executed by the parties,  Tenant shall be deemed a  trespasser.  If Tenant
pays, and Landlord  accepts,  rent for a period after termination of this Lease,
Tenant shall be deemed to be occupying  the Premises only as a Tenant from month
to month,  subject to all the terms,  conditions,  and agreements of this Lease,
except that the rent shall be two times the monthly rent  specified in the Lease
immediately before termination.

SUBORDINATION AND ATTORNMENT
20. Landlord  reserves the right to place liens and encumbrances on the Premises
superior in lien and effect to this lease,  This Lease, and all rights of Tenant
hereunder,  shall, at the option of Landlord,  be subject and subordinate to any
liens and encumbrances now or hereafter imposed by Landlord upon the Premises or
the Real Estate or any part thereof, and Tenant agrees to execute,  acknowledge,
and deliver to  Landlord,  upon  request,  any and all  instruments  that may be
necessary or proper to subordinate  this Lease and all rights herein to any such
lien or encumbrance as may be required by Landlord.

In the event any  proceedings are brought for the foreclosure of any mortgage on
the Premises,  Tenant will attorn to the purchaser at the  foreclosure  sale and
recognize  such purchaser as the Landlord  under this Lease.  The purchaser,  by
virtue  of such  foreclosure,  shall be deemed to have  assumed,  as  substitute
Landlord, the terms and conditions of


<PAGE>



this  Lease  until  the  resale  or  other  disposition  of its  interest.  Such
assumption,  however,  shall not be deemed an acknowledgment by the purchaser of
the validity of any then existing claims of Tenant against the prior Landlord.

Tenant  agrees  to  execute  and  deliver  such  further  assurances  and  other
documents,  including a new lease upon the same terms and  conditions  contained
herein,  confirming  the foregoing,  as such  purchaser may reasonably  request.
Tenant waives any right of election to terminate  this Lease because of any such
foreclosure proceedings.

                                       NOTICE
21. Any notice of demands to be given  hereunder  shall be given in writing  and
sent by registered or certified  mail to Landlord at Century  Development,  3323
North 107th Street,  Omaha,  Nebraska  68134 and to Tenant at Advanced  Business
Sciences, Inc., 3345 North 107 th Street, Omaha, Nebraska 68134 or at such other
address as either party may from time to time  designate  in writing.  Each such
notice  shall be deemed to have  been  given at the time it shall be  personally
delivered to such  address or deposited in the United  States mail in the manner
prescribed herein.

RIGHT TO TERMINATE
22.  Landlord  shall  have the right to  terminate  this Lease at the end of any
calendar  month by giving the Tenant  written  notice at least six months before
the date of the  termination  of  Landlord's  intention  to  remodel,  remove or
demolish  the  Premises,  or to  sell,  or  make a  ground  lease  of  the  land
thereunder.

RULES AND REGULATIONS
23. Tenant and Tenant's  agents,  employees and invitees shall fully comply with
all rules and  regulations  of the Veal  Estate,  as amended  from time to time,
which are made a part of this lease as if fully set forth herein. Landlord shall
have the right to amend such rules and  regulations as Landlord deems  necessary
or  desirable  for the safety,  care,  cleanliness,  or proper  operation of the
Premises and the Real Estate.

NET LEASE
24. This is a net-net-net Lease and the parties agree and understand that Tenant
shall  pay  Tenant's  proportionate  share of the  real  estate  taxes,  special
assessments,  insurance  and  all  other  Operating  Expenses  as  described  in
subparagraph 4.b of this Lease.

MISCELLANEOUS
25. (a) Binding on Assigns. All terms, conditions,  and agreements of this Lease
shall be binding upon,  apply,  and inure to the benefit of the parities  hereto
and their  respective  heirs,  representatives,  successors,  and  assigns.  (b)
Amendment  in Writing.  This Lease  contains  the entire  agreement  between the
parties and may be amended ~i, only by subsequent written agreement.  (c) Waiver
- - None. The failure of Landlord to insist upon strict  performance of any of the
terms,  conditions  and agreements of this Lease shall not be deemed a waiver of
any of its rights or remedies  hereunder and shall not be deemed a waiver of any
subsequent breach or default of any of such terms,  conditions,  and agreements.
The  doing of  anything  by  Landlord  which  Landlord  is not  obligated  to do
hereunder shall not impose any future obligation on Landlord nor otherwise amend
any provision of this Lease.  (d) No Surrender.  No surrender of the Premises by
Tenant shall be effected by Landlord's acceptance of the keys to the Premises or
of the rent due hereunder, or by any other means whatsoever,  without Landlord's
written  acknowledgment  that  such  acceptance  constitutes  a  surrender.  (e)
Captions.  The  captions  of the  various  paragraphs  in  this  Lease  are  for
convenience only and do not define, limit, describe, or construe the contents of
such paragraphs.  (f) Brokers. Tenant hereby warrants that no real estate broker
has or will represent it in this transaction and that


<PAGE>



no finder's  fees have been earned by a third  party.

          (g)  Applicable  Law. This Lease shall be governed by and construed in
     accordance with the laws of the State of Nebraska.

Until  this  Lease is  executed  on behalf of all  parties  hereto,  it shall be
construed as an offer to lease of Tenant to Landlord.



<PAGE>




IN WITNESS WHEREOF, the parties hereto have executed this Lease the day and year
first above written.

F & J Enterprises, Inc.
Landlord

Witness   By:____________________

Advanced Business Sciences, Inc.
Tenant

Witness  By:_____________________






      Commercial Savings Bank FIXED RATE
      627 North Adams - P.O. Box 277 REVOLVING OR
      Carroll, Iowa 51401-0277 - 712-792-4346 DRAW NOTE
      "LENDER"
                                   Borrower
                       Advanced Business Sciences, Inc.
                          3345... NORTH 107TH STREET
                               Omaha, NE 68134

                   TELEPHONE NO.
                   IDENTIFICATION NO-. 47-075198


OFFICER         INTEREST        PRINCIPAL AMOUNT/        FUNDING /
MATURITY     CUSTOMER             LOAN
INITIALS         RATE         CREDIT LIMIT               AGREEMENT   DATE
            NUMBER                 NUMBER

005             8.000%              $999,767.13                      04/04/99
10/05/99         1-21--534
PURPOSE: REFINANCE NOTE 45697 - OPERATING

PROMISE TO PAY:  For value  received,  Borrower  promises to pay to the order of
Lender,  indicated  above,  the  principal  amount of NINE  HUNDRED  NINETY-NINE
THOUSAND SEVEN HUNDRED  SIXTY-SEVEN  AND 13/100  -Dollars ($ 999,767.13)  or, if
less,  the aggregate  unpaid  principal  amount of all loans or advances made by
Lender to Borrower,  plus interest on the unpaid  principal  balance at the rate
and in the manner described  below,  until all amounts owing under this Note are
paid in full. All amounts received by Lender shall be applied first to expenses,
late charges,  accrued unpaid interest, and then to unpaid principal,  or in any
other order as determined by Lender,  in Lender's sole discretion,  as permitted
by law.  REVOLVING OR DRAW FEATURE:  x This Note possesses a revolving  feature.
Upon  satisfaction  of all conditions set forth in this Note,  Borrower shall be
entitled to borrow up to the full principal  amount of the Note and to repay and
re-borrow  from time to time during the term of the Note.  This Note possesses a
draw  feature.  Upon  satisfaction  of all  conditions  set forth in this  Note,
Borrower  shall be  entitled  to make one or more draws  under  this  Note.  Any
repayment may not be re-borrowed.  The aggregate  amount of such draws shall not
exceed the full principal  amount of this Note.  Information  with regard to any
loans or advances  under this Note shall be recorded and maintained by Lender in
Its Internal  records and such records  shall be conclusive of the principal and
interest  owed by Borrower  under this Note unless there Is a material  error in
such  records.  Lender's  failure  to record  the date and amount of any loan or
advance shall not


<PAGE>



limit or otherwise  affect the  obligations of Borrower under this Note to repay
the  principal  amount  of the  loans or  advances  together  with all  interest
accruing thereon.  Lender shall not be obligated to provide Borrower with a copy
of the record on a periodic  basis.  Borrower  shall be  entitled  to inspect or
obtain a copy of the record  during  Lender's  business  hours.  CONDITIONS  FOR
ADVANCES:  If there is no default under this Note, Borrower shall be entitled to
borrow monies under this Note (subject to the limitations described above) under
the following conditions:

INTEREST  RATE:  Interest  under this Note shall be computed on the basis of 365
days and the  actual  number  of days per year.  So long as there is no  default
under this Note,  interest on this Note shall be calculated at the fixed rate of
EIGHT AND  N0/1000  percent  (8.000 %) per annum or the  maximum  interest  rate
Lender is permitted to charge by law,  whichever is less.  DEFAULT  RATE: In the
event of any  default  under  this  Note,  the Lender  may,  in its  discretion,
determine that all amounts owed to Lender shall bear Interest at the lesser of:

or the maximum interest rate Lender is permitted to charge by law.
PAYMENT SCHEDULE: Borrower shall pay the principal and interest according to the
following schedule:

A SINGLE PAYMENT OF THE UNPAID PRINCIPAL BALANCE PLUS ACCRUED
INTEREST IS DUE AND PAYABLE ON OCTOBER 5, 1999.

All payments will be made to Lender at Its address described above, or at any
other address so designated by Lender, and In lawful currency of the United
States of America.

RENEWAL: If checked,  X  this Note is a renewal of Loan Number 45697

SECURITY:  To secure the payment and  performance of obligations  incurred under
this Note,  Borrower  grants  Lender a security  interest  in, and  pledges  and
assigns to Lender, all of Borrower's rights, title, and interest, in all monies,
Instruments,  savings,  checking  and  other  deposit  accounts  of  Borrower's,
(excluding  IRA, Keogh and trust accounts and deposits  subject to tax penalties
If so assigned) that are now or in the future in Lender's custody or control.  X
If checked, the obligations under this Note are also secured by a lien on and/or
security  interest  in the  property  described  in the  documents  executed  in
connection  with this Note as well as any other property  designated as security
for this Note now or in the future.

          PREPAYMENT:  This Note may be  prepaid In part or in full on or before
     its maturity date. If this Note is prepaid in full, there will be:
     No  minimum   finance   charge     A  minimum   finance  charge  of
     --------------------.  LATE PAYMENT  CHARGES:  If payment is received  more
     than n/a days  late,  Borrower  will be charged a late  payment  charge of:
       _________% of the unpaid payment  amount;   $ or % of the
     unpaid payment  amount,  whichever is   greater  l less; as
     additional interest.

IMPORTANT: READ BEFORE SIGNING. THE TERMS OF THIS AGREE AGREEMENT
SHOULD BE READ CAREFULLY BECAUSE ONLY THOSE TERMS IN WRITING ARE


<PAGE>



ENFORCEABLE. NO OTHER TERMS OR ORAL PROMISES NOT CONTAINED IN THIS
WRITTEN CONTRACT MAY BE LEGALLY ENFORCED. BORROWER MAY CHANGE
THE TERMS OF THIS AGREEMENT ONLY BY ANOTHER WRITTEN AGREEMENT.
THIS NOTICE ALSO APPLIES TO ANY OTHER CREDIT AGREEMENTS (EXCEPT
EXEMPT TRANSACTIONS) NOW IN EFFECT BETWEEN YOU AND THIS LENDER.

BORROWER  ACKNOWLEDGES  THAT BORROWER HAS READ,  UNDERSTANDS,  AND AGREES TO TYE
TERMS AND  CONDITIONS OF THIS NOTE INCLUDING THE PROVISIONS ON THE REVERSE SIDE;
BORROWER ACKNOWLEDGES RECEIPT OF AN EXACT COPY OF THIS NOTE.

NOTE DATE: APRIL 5, 1999
BORROWER:  ADVANCED BUSINESS SCIENCES, INC.BORROWER:
   ADVANCED BUSINESS SCIENCES, INC.

   BENJAMIN  J. LAMB, PRESIDENT & CEO          ROGER J. KANNE DIRECTOR &
TREASURER
BORROWER, BORROWER:
BORROWER: BORROWER:
BORROWER: BORROWER:




<PAGE>



TERMS AND CONDITIONS
I -  DEFAULT:  Borrower  will be in  default  under  this Note In the event that
Borrower,  any guarantor or any other third party pledging  collateral to secure
this Note: (a) falls to make any payment on this Note or any other  indebtedness
to Lender when due; (b) falls to perform any obligation or breaches any warranty
or covenant to Lender  contained In this Note, any security  Instrument,  or any
other  present  or  future  written  agreement   regarding  this  or  any  other
indebtedness  of  Borrower  to  Lender;  (c)  provides  or  causes  any false or
misleading  signature or representation to be provided to Lender; (d) allows the
collateral securing this Note Of any) to be lost, stolen, destroyed,  damaged in
any material respect,  or subjected to seizure or confiscation;  (e) permits the
entry or service of any  garnishment,  judgment,  tax levy,  attachment  or lien
against  Borrower,  any guarantor,  or any of their property;  (Q dies,  becomes
legally Incompetent, Is dissolved or terminated, ceases to operate Its business,
becomes  insolvent,  makes an assignment for the benefit of creditors,  falls to
pay debts as they become due,  has a material  adverse  change In its  financial
condition,  or becomes  the  subject  of any  bankruptcy,  Insolvency  or debtor
rehabilitation  proceeding;  or (9) causes Lender, in good faith, to believe the
prospect of payment or performance is impaired.  2. RIGHTS OF LENDER ON DEFAULT:
If there Is a default  under this Note,  Lender will be entitled to exercise one
or more of the following  remedies  without notice or demand (except as required
by law): (a) to cease making additional advances under this Note; (b) to declare
the principal amount plus accrued Interest under this Note and all other present
and future  obligations of Borrower  Immediately due and payable In full; (c) to
collect the  outstanding  obligation  of Borrower  with or without  resorting to
judicial  process;  (d) to  take  possession  of any  collateral  in any  manner
permitted  by law;  (e) to require  Borrower  to deliver and make  available  to
Lender any collateral at a place  reasonably  convenient to Borrower and Lender;
(f) to sell,  lease or  otherwise  dispose of any  collateral  and  collect  any
deficiency  balance with or without  resorting to legal process;  (g) to set-off
Borrower's  obligations against any amounts due to Borrower  Including,  but not
limited to monies, Instruments, and deposit accounts maintained with Lender; and
(h) to exercise  all other rights  available  to Lender under any other  written
agreement or applicable law. Lender's rights are cumulative and may be exercised
together,  separately,  and In any order. Lender's remedies under this paragraph
are In addition to those available at common law, Including, but not limited to,
the right of set-off. 3. DEMAND FEATURE: If this Note contains a demand feature,
Lender's right to demand payment,  at any time, and from time to time,  shall be
In  Lender's  sole and  absolute  discretion,  whether  or not any  default  has
occurred. 4. FINANCIAL INFORMATION: Borrower will at all times keep proper books
of record and account In which full,  true and correct  entries shall be made in
accordance with generally accepted accounting  principles and will upon Lender's
request deliver to Lender,  within ninety (90) days after the end of each fiscal
year of Borrower, a copy of the annual financial statements of Borrower relating
to such  fiscal  year,  such  statements  to include  (1) the  balance  sheet of
Borrower  as at the  end of  such  fiscal  year  and  (11)  the  related  income
statement, statement of retained earnings and statement of


<PAGE>



changes in the financial  position of Borrower for such fiscal year,  which,  at
Lender's request,  shall be prepared by such certified public accountants as may
be reasonably  satisfactory to Lender. Borrower also agrees to deliver to Lender
within  fifteen (15) days after filing  same,  a copy of  Borrower's  income tax
returns  and also,  from time to time,  such other  financial  Information  with
respect to Borrower  as Lender may  request.  S.  MODIFICATION  AND WAIVER:  The
modification or waiver of any of Borrower's obligations or Lender's rights under
this Note must be  contained in a writing  signed by Lender.  Lender may perform
any of  Borrower's  obligations  or delay or fail to exercise  any of its rights
without  causing  a waiver  of those  obligations  or  rights.  A waiver  on one
occasion  will  not  constitute  a  waiver  on any  other  occasion.  Borrower's
obligations under this Note shall not be affected If Lender amends, compromises,
exchanges,  fails  to  exercise,  Impairs  or  releases  any of the  obligations
belonging  to any  co-borrower  or  guarantor  or any of its rights  against any
co-borrower,  guarantor or  collateral.  6.  SEVERABILITY/MAXIMUM  RATE:  If any
provision  of this Note is  invalid,  Illegal or  unenforceable,  the  validity,
legality, and enforceability of the remaining provisions shall not In any way be
affected or Impaired  thereby.  Notwithstanding  any reference to highest lawful
rate,  maximum  Interest  rate  permitted to be charged by relevant law or other
like terms,  such  references  shall not be deemed to establish a maximum lawful
rate of Interest as contemplated by Iowa Code 9 535.2,2 because the parties have
agreed in writing to a rate of interest  pursuant to Iowa Code  111535.2.  There
shall be no automatic reduction to the highest lawful rate or other like term a3
to any  Borrower or any other party  barred by law from  availing  Itself In any
action or  proceedings  of the defense of usury,  or any Borrower or other party
barred or exempted from the operation of any law limiting the amount of interest
that may be paid for the loan or use of money, or In the event this transaction,
because  of its amount or  purpose  or for any other  reason is exempt  from the
operation of any statute limiting t6 amount of interest that may be paid for the
loan or use of money. Borrower agrees that any late charge,  delinquency charge,
or  other  like  charge  shall be  interest  for the  purpose  of Iowa  Law.  7.
ASSIGNMENT:  Borrower will not be entitled to assign any of its rights, remedies
or  obligations  described  In this Note  without the prior  written  consent of
Lender  which may be withhold by Lender In Its sole  discretion.  Lender will be
entitled to assign some or all of its rights and remedies described in this Note
without  notice to or the prior  consent of  Borrower  In any  manner.  The term
*Lender" shall mean the Lender  specified in this Agreement,  Its successors and
assigns,  and  subsequent  holders of this Note. 8. NOTICE:  Any notice or other
communication  to be provided to Borrower or Lender  under this Note shall be In
writing and sent to the parties at the addresses  described In this Note or such
other  address as the parties may  designate  In writing  from time to time.  9.
APPLICABLE  LAW:  This Note shall be  governed by the laws of the state of Iowa.
Borrower  consents to the  jurisdiction  and venue of any court  located In such
state In the  event  of any  legal  proceeding  pertaining  to the  negotiation,
execution, performance or enforcement of any term or condition contained In this
Note or any related  loan  document and agrees not to commence or seek to remove
such legal  proceeding In or to a different  court.  10.  COLLECTION  COSTS:  If
Lender hires an attorney to assist in collecting any amount due or enforcing any
right or remedy  under this Note,  Borrower  agrees to pay  Lender's  reasonable
attorneys'  fees and collection  costs.  11.  MISCELLANEOUS:  This Note is being
executed for Commercial purposes. Borrower and Lender agree that time is of the


<PAGE>



essence. Borrower waives presentment, demand for payment, notice of dishonor and
protest.  All  references  to  Borrower  In this Note shall  include  all of the
parties  signing  this  Note,  and this Note  shall be  binding  upon the heirs,
successors  and  assigns  of  Borrower  and  Lender.  If there is more  than one
Borrower, their Obligations will be joint and several. This Note and any related
documents represent the complete and integrated  understanding  between Borrower
and Lender  pertaining to the terms and conditions of those documents.  12. JURY
TRIAL WAIVER:  BORROWER  HEREBY WAIVES ANY RIGHT TO A TRIAL BY JURY IN ANY CIVIL
ACTION ARISING OUT OF, OR BASED UPON, THIS NOTE OR THE COLLATERAL  SECURING THIS
NOTE.  13.  ADDITIONAL  TERMS:  THIS NOTE IS  SECURED  BY A  LIMITED  CONTINUING
GUARANTY  DATED APRIL 6, 1998,  IN THE AMOUNT OF $285,000 FROM MARY COLLISON AND
BY A LIMITED CONTINUING GUARANTY DATED APRIL 6, 1998, IN THE AMOUNT OF $ 285,000
FROM ROGER J. KANNE AND BY A LIMITED CONTINUING GUARANTY DATED APRIL 6, 1998, IN
THE AMOUNT OF  $285,000.00  FROM JANES L.  PIETIG AND BY A L IMI TMD  CONTINUING
GUARANTY  DATED  APRIL 6, 1998,  IN THE  AMOUNT OF  $285,000.00  FROM  DENNIS L.
ANDERSON AND BY A LIMITED CONTINUING GUARANTY DATED APRIL 6, 1998, IN THE AMOUNT
OF $285,000.00 FROM ROBERT E. BADDING AND BY A LIMITED CONTINUING GUARANTY DATED
APRIL 6, 1998, IN THE AMOUNT OF $285,000.00 FROM MARTIN J. HALBUR.




                                PROMISSORY NOTE
Principal   Loan Date       Maturity   Loan No.  Call  Collateral        Account
     Officer          Initials
$1,000,000.00    04/08/1998      06/01/1999       005281              1735062078
  CO8
     References  in the shaded area are for  Lender's  use only and do not limit
the applicability of this document to any particular loan or item.

Borrower: Advanced Business Sciences, Inc.  Lender: U.S. Bank
National Association
          3345 N. 107th Street                      88th & Center
          Omaha, NE 68134                           8800 West Center Road
                                                    Omaha, NE 68124

Principal Amount: $1,000,000.00 Initial Rate: 10.500%        Date of
Note: April 8, 1998

PROMISE TO PAY. Advanced Business Sciences, Inc. ("Borrower") promises
to pay to U.S. Bank National  Association  ("Lender"),  or order, In lawful
money of the United States of America,  the principal amount of One Million
& 00/100 Dollars ($1,000,000.00) or so much as may be outstanding, together
with Interest on the unpaid outstanding  principal balance of each advance.
Interest shall be calculated  from the date of each advance until repayment
of each advance.

PAYMENT. Borrower will pay this loan In one payment of all outstanding principal
plus all accrued unpaid interest on June 1, 1999. In addition, Borrower will pay
regular monthly  payments of accrued unpaid Interest  beginning May 1, 1998, and
all  subsequent  interest  payments  are due on the same day of each month after
that.  The annual  interest  rate for this Note is computed on a 365/360  basis;
that is, by applying  the ratio of the annual  interest  rate over a year of 360
days, multiplied by the outstanding principal balance,  multiplied by the actual
number of days the principal balance is outstanding. Borrower will pay Lender at
Lender's  address  shown above or at such other place as Lender may designate in
writing. Unless otherwise agreed or required by applicable law, payments will be
applied first to accrued unpaid interest,  then to principal,  and any remaining
amount to any unpaid collection costs and late charges.

VARIABLE INTEREST RATE. The interest rate on this Note is subject to change from
time to time  based on  changes  in an index  which  is the U.S.  Bank  National
Association  Reference  Rate (the  "Index").  The Index is not  necessarily  the
lowest  rate  charged  by  Lender  on its loans and is set by Lender in its sole
discretion.  If the Index  becomes  unavailable  during  the term of this  loan,
Lender may designate a substitute  index after notifying  Borrower.  Lender will
tell  Borrower  the  current  Index  rate  upon  Borrower's  request.   Borrower
understands  that  Lender  may make  loans  based on  other  rates as well.  The
interest  rate  change  will not occur  more  often  than  each  day.  The Index
currently  IS 8.500% per annum.  The  Interest  rate to be applied to the unpaid
principal


<PAGE>



balance  of this  Note  will be at a rate of 2.000  percentage  points  over the
Index,  resulting  In an Initial  rate of 10.500%  per annum.  NOTICE:  Under no
circumstances  will the interest rate on this Note be more than the maximum rate
allowed by applicable law.

PREPAYMENT. Borrower may pay all or a portion of the amount owed earlier than it
is due. Early payments will not, unless agreed to by Lender in writing,  relieve
Borrower of Borrower's obligation to continue to make payments of accrued unpaid
interest. Rather, they will reduce the principal balance due.

DEFAULT.  Borrower  will be in  default  if any of the  following  happens:  (a)
Borrower  fails to make any payment when due.  (b)  Borrower  breaks any promise
Borrower has made to Lender, or Borrower fails to comply with or to perform when
due any other term, obligation, covenant, or condition contained in this Note or
any agreement  related to this Note, or in any other  agreement or loan Borrower
has with Lender. (c) Any representation or statement made or furnished to Lender
by Borrower  or on  Borrower's  behalf is false or  misleading  in any  material
respect  either  now or at the time  made or  furnished.  (d)  Borrower  becomes
insolvent, a receiver is appointed for any part of Borrower's property, Borrower
makes an assignment for the benefit of creditors, or any proceeding is commenced
either by Borrower or against  Borrower under any bankruptcy or insolvency laws.
(e) Any creditor tries to take any of Borrower's  property on or in which Lender
has a  lien  or  security  interest.  This  includes  a  garnishment  of  any of
Borrower's  accounts  with Lender.  (f) Any  guarantor  dies or any of the other
events described in this default section occurs with respect to any guarantor of
this  Note.  (g) A  material  adverse  change  occurs  in  Borrower's  financial
condition,  or Lender  believes  the prospect of payment or  performance  of the
Indebtedness is impaired. (h) Lender in good faith deems itself insecure.

If any default,  other than a default in payment, is curable and if Borrower has
not been given a notice of a breach of the same  provision  of this Note  within
the preceding twelve (12) months,  it may be cured (and no event of default will
have occurred) if Borrower, after receiving written notice from Lender demanding
cure of such default:  (a) cures the default within fifteen (15) days; or (b) if
the cure requires more than fifteen (15) days, immediately initiates steps which
Lender deems in Lender's  sole  discretion  to be sufficient to cure the default
and  thereafter  continues  and  completes all  reasonable  and necessary  steps
sufficient to produce compliance as soon as reasonably practical.

LENDER'S  RIGHTS.  Upon default,  Lender may declare the entire unpaid principal
balance on this Note and all accrued unpaid interest  immediately  due,  without
notice, and then Borrower will pay that amount. Upon default,  including failure
to pay upon final maturity,  Lender, at its option, may also, if permitted under
applicable  law,  increase  the  variable  interest  rate on this  Note to 5.000
percentage  points over the Index. The interest rate will not exceed the maximum
rate  permitted by applicable  law.  Lender may hire or pay someone else to help
collect this Note if Borrower  does not pay.  Borrower also will pay Lender that
amount.  This includes,  subject to any limits under  applicable  law,  Lender's
attorneys'  fees and Lender's legal expenses  whether or not there is a lawsuit,
including  attorneys'  fees  and  legal  expenses  for  bankruptcy   proceedings
(including  efforts  to modify  or vacate  any  automatic  stay or  injunction),
appeals,  and  any  anticipated   post-judgment   collection  services.  If  not
prohibited  by  applicable  law,  Borrower  also  will pay any court  costs,  in
addition to all other sums  provided  by law.  This Note has been  delivered  to
Lender and accepted by Lender in the


<PAGE>



State of Nebraska. If there is a lawsuit,  Borrower agrees upon Lender's request
to submit to the  jurisdiction  of the  courts of Douglas  County,  the State of
Nebraska.  This Note shall be governed by and construed In  accordance  with the
laws of the State of Nebraska.

RIGHT OF SETOFF.  Borrower grants to Lender a contractual  security interest in,
and hereby  assigns,  conveys,  delivers,  pledges,  and transfers to Lender all
Borrower's right, title and interest in and to, Borrower's accounts with Lender.
(whether checking, savings, or some other account), including without limitation
all accounts  held jointly with someone else and all accounts  Borrower may open
in the  future,  excluding  however  all IRA and Keogh  accounts,  and all trust
accounts for which the grant of a security  interest would be prohibited by law.
Borrower authorizes Lender, to the extent permitted by applicable law, to charge
or setoff all sums owing on this Note against any and all such accounts.

COLLATERAL. This Note is secured by FS/SA all inclusive.

LINE OF CREDIT.  This Note evidences a revolving line of credit.  Advances under
this Note may be requested orally by Borrower or by an authorized person. Lender
may, but need not,  require that all oral requests be confirmed in writing.  All
communications,  instructions, or directions by telephone or otherwise to Lender
are to be  directed to Lender's  office  shown  above.  The  following  party or
parties are authorized to request advances under the line of credit until Lender
receives  from  Borrower  at Lender's  address  shown  above  written  notice of
revocation of their authority: Rob Rasmussen and Roger Kanne. Borrower agrees to
be liable for all sums either:  (a) advanced in accordance with the instructions
of an  authorized  person or (b)  credited to any of  Borrower's  accounts  with
Lender.  The  unpaid  principal  balance  owing on this  Note at any time may be
evidenced  by  endorsements  on  this  Note  or by  Lender's  internal  records,
including daily computer  print-outs.  Lender will have no obligation to advance
funds under this Note if: (a) Borrower or any  guarantor is in default under the
terms of this Note or any  agreement  that  Borrower or any  guarantor  has with
Lender,  including  any agreement  made in  connection  with the signing of this
Note; (b) Borrower or any guarantor  ceases doing business or is insolvent;  (c)
any guarantor  seeks,  claims or otherwise  attempts to limit,  modify or revoke
such  guarantor's  guarantee  of this Note or any other  loan with  Lender;  (d)
Borrower has applied  funds  provided  pursuant to this Note for purposes  other
than those  authorized  by Lender;  or (e)  Lender in good  faith  deems  itself
insecure under this Note or any other agreement between Lender and Borrower.

PURPOSE OF LOAN.   Working Capital.

GENERAL  PROVISIONS.  Lender may delay or forgo  enforcing  any of its rights or
remedies under this Note without losing them.  Borrower and any other person who
signs,  guarantees or endorses this Note,  to the extent  allowed by law,  waive
presentment, demand for payment, protest and notice of dishonor. Upon any change
in the terms of this Note, and unless otherwise expressly


<PAGE>



stated in writing,  no party who signs this Note,  whether as maker,  guarantor,
accommodation  maker or endorser,  shall be released  from  liability.  All such
parties agree that Lender may renew or extend  (repeatedly and for any length of
time) this loan,  or release any party or  guarantor or  collateral;  or impair,
fail to realize upon or perfect  Lender's  security  interest in the collateral;
and take any other action deemed  necessary by Lender  without the consent of or
notice to anyone.  All such  parties also agree that Lender may modify this loan
without  the  consent of or notice to anyone  other than the party with whom the
modification is made.




<PAGE>



04-08-1998                              PROMISSORY NOTE
                                            Page  2
Loan No. 005281                           (Continued)

PRIOR TO SIGNING THIS NOTE, BORROWER READ AND UNDERSTOOD ALL THE
PROVISIONS OF HIS NOTE, INCLUDING THE VARIABLE INTEREST RATE PROVISIONS.
BORROWER AGREES TO THE TERMS OF THE NOTE  AND ACKNOWLEGES RECEIPT
OF A COMPLETED COPY OF THE NOTE.

BORROWER:

Advanced Business Sciences, Inc.

BY                                             By:
     Ron Muhlbauer, President  Rob Rasmussen, Chief Operating Officer

B                                              By:

John Gaukel, Vice President R & D
     Roger Kanne, Treasurer
               NT
Variable Rate. Line of Credit.




<PAGE>



                          CHANGE IN TERMS AGREEMENT
Principal Loan Date       Maturity Loan No.      Call Collateral        Account
     Officer          Initials
$1,000,000.00 08-15-1999         34             3886                 1735062078
  MEE08

References in the shaded area are for Lender's use only and do not limit the
applicability of this document to any particular loan or item.
Borrower:Advanced Business Sciences, Inc.Lender:  U.S. Bank National Association
         3345 N. 107th Street                        88th & Center    8800 West
Center Road
            Omaha, NE 68134                             Omaha, NE  68124
Principal Amount: $1,000,000.00
                                                 Date of Agreement: June 1,1999
DESCRIPTION OF EXISTING INDEBTEDNESS. Revolving Promissory Note dated April
8,1998, in the original amount of $1,000,000.00.
DESCRIPTION OF COLLATERAL. FS/SA all business assets.
DESCRIPTION OF CHANGE IN TERMS. Extend current maturity date of June 1, 1999, to
become due on August 15, 1999, All other terms and conditions shall remain the
same.

PROMISE TO PAY. Advanced Business Sciences, Inc. ("Borrower") promises to pay to
U.S.  Bank National  Association  ("Lender"),  or order,  in lawful money of the
United States of America,  the principal  amount of One Million & 00/100 Dollars
($1,000,000.00) or so much as may be outstanding,  together with Interest on the
unpaid  outstanding  principal  balance  of  each  advance.  Interest  shall  be
calculated from the date of each advance until repayment of each advance.

PAYMENT. Borrower will pay this loan in one payment of all outstanding principal
plus all accrued unpaid Interest on August 15, 1999. In addition,  Borrower will
pay regular monthly payments of accrued unpaid interest  beginning July 1, 1999,
and all subsequent Interest payments are due on the same day of each month after
that.  The annual  interest  rate for this  Agreement  is  computed on a 365/360
basis;  that is, by applying,  the ratio of the annual interest rate over a year
of 360 days, multiplied by the outstanding principal balance,  multiplied by the
actual number of days the principal  balance is  outstanding.  Borrower will pay
Lender at  Lender's  address  shown  above or at such other  place as Lender may
designate in writing.  Unless  otherwise  agreed or required by applicable  law,
payments will be applied first to accrued  unpaid  interest,  then to principal,
and any remaining amount to any unpaid collection costs and late charges.

VARIABLE INTEREST RATE. The interest rate on this Agreement is subject to change
from time to time based on changes in an index which is the U.S.  Bank  National
Association  Reference  Rate (the  "Index").  The Index is not  necessarily  the
lowest  rate  charged  by  Lender  on its loans and is set by Lender in its sole
discretion.  If the Index  becomes  unavailable  during  the term of this  loan,
Lender may designate a substitute  index after notifying  Borrower.  Lender will
tell  Borrower  the  current  Index  rate  upon  Borrower's  request.   Borrower
understands that Lender may make loans


<PAGE>



based on other rates as well. The interest rate change will not occur more often
than each day. The Index currently is 7.750% per annum.  The interest rate to be
applied to the unpaid  principal  balance of this Agreement will be at a rate of
2.000 percentage  points over the Index,  resulting in an initial rate of 9.750%
per  annum.  NOTICE:  Under  no  circumstances  will the  interest  rate on this
Agreement be more than the maximum rate allowed by applicable law.

PREPAYMENT. Borrower may pay without penalty all or a portion of the amount owed
earlier than it is due. Early  payments will not,  unless agreed to by Lender in
writing,  relieve Borrower of Borrower's obligation to continue to make payments
of accrued unpaid interest. Rather, they will reduce the principal balance due.

DEFAULT.  Borrower  will be in  default  if any of the  following  happens:  (a)
Borrower  fails to make any payment when due.  (b)  Borrower  breaks any promise
Borrower has made to Lender, or Borrower fails to comply with or to perform when
due any  other  term,  obligation,  covenant,  or  condition  contained  in this
Agreement or any agreement related to this Agreement,  or in any other agreement
or loan Borrower has with Lender.  (c) Any  representation  or statement made or
furnished to Lender by Borrower or on  Borrower's  behalf is false or misleading
in any  material  respect  either  now or at the  time  made or  furnished.  (d)
Borrower becomes  insolvent,  a receiver is appointed for any part of Borrower's
property,  Borrower  makes an assignment  for the benefit of  creditors,  or any
proceeding  is  commenced  either by  Borrower  or  against  Borrower  under any
bankruptcy or insolvency  laws. (e) Any creditor tries to take any of Borrower's
property on or in which Lender has a lien or security interest.  This includes a
garnishment of any of Borrower's accounts with Lender. (f) Any guarantor dies or
any of the other events described in this default section occurs with respect to
any  guarantor  of this  Agreement.  (g) A  material  adverse  change  occurs in
Borrower's  financial  condition,  or Lender believes the prospect of payment or
performance  of the  Indebtedness  is  impaired.  (h) Lender in good faith deems
itself insecure.

If any default,  other than a default in payment, is curable and if Borrower has
not been  given a notice of a breach  of the same  provision  of this  Agreement
within  the  preceding  twelve  (12)  months,  it may be cured  (and no event of
default will have  occurred) if Borrower,  after  receiving  written notice from
Lender demanding cure of such default: (a) cures the default within fifteen (15)
days;  or (b) if the cure  requires  more than  fifteen  (16) days,  immediately
initiates  steps which Lender deems in Lender's sole discretion to be sufficient
to cure the default and  thereafter  continues and completes all  reasonable and
necessary  steps  sufficient  to  produce   compliance  as  soon  as  reasonably
practical.

LENDER'S  RIGHTS.  Upon default,  Lender may declare the entire unpaid principal
balance on this  Agreement  and all accrued  unpaid  interest  immediately  due,
without notice, and then Borrower will pay that amount. Upon default,  including
failure  to pay upon  final  maturity,  Lender,  at its  option,  may  also,  if
permitted  under  applicable  law,  increase the variable  interest rate on this
Agreement to 5.000 percentage  points over the Index. The interest rate will not
exceed the maximum rate  permitted  by  applicable  law.  Lender may hire or pay
someone else to help collect this  Agreement if Borrower does not pay.  Borrower
also will pay Lender that  amount.  This  includes,  subject to any limits under
applicable law, Lender's  attorneys' fees and Lender's legal expenses whether or
not  there is a  lawsuit,  including  attorneys'  fees and  legal  expenses  for
bankruptcy proceedings (including


<PAGE>



efforts to modify or vacate any automatic stay or injunction),  appeals, and any
anticipated  post-judgment  collection services. If not prohibited by applicable
law,  Borrower  also will pay any court  costs,  in  addition  to all other sums
provided by law.  This  Agreement  has been  delivered to Lender and accepted by
Lender in the State of  Nebraska.  If there is a lawsuit,  Borrower  agrees upon
Lender's  request to submit to the jurisdiction of the courts of Douglas County,
the State of  Nebraska.  This  Agreement  shall be governed by and  construed In
accordance with the laws of the State of Nebraska,

RIGHT OF SETOFF.  Borrower grants to Lender a contractual  security interest in,
and hereby  assigns,  conveys,  delivers,  pledges,  and transfers to Lender all
Borrower's right, title and interest in and to, Borrower's  accounts with Lender
(whether checking, savings, or some other account), including without limitation
all accounts  held jointly with someone else and all accounts  Borrower may open
in the  future,  excluding  however  all IRA and Keogh  accounts,  and all trust
accounts for which the grant of a security  interest would be prohibited by law.
Borrower authorizes Lender, to the extent permitted by applicable law, to charge
or setoff all sums owing on this Agreement against any and all such accounts.

LINE OF CREDIT.  This Agreement  evidences a revolving line of credit.  Advances
under this  Agreement  may be requested  orally by Borrower or by an  authorized
person. Lender may, but need not, require that all oral requests be confirmed in
writing.  All  communications,  instructions,  or  directions  by  telephone  or
otherwise  to Lender are to be directed  to Lender's  office  shown  above.  The
following party or parties are authorized to request  advances under the line of
credit until  Lender  receives  from  Borrower at Lender's  address  shown above
written notice of revocation of their authority:  Rob Rasmussen and Roger Kanne.
Borrower  agrees to be liable for all sums either:  (a)  advanced in  accordance
with  the  instructions  of an  authorized  person  or  (b)  credited  to any of
Borrower's  accounts  with Lender.  The unpaid  principal  balance owing on this
Agreement at any time may be evidenced by  endorsements  on this Agreement or by
Lender's internal records, including daily computer print-outs. Lender will have
no  obligation  to advance  funds under this  Agreement  if: (a) Borrower or any
guarantor is in default under the terms of this  Agreement or any agreement that
Borrower or any  guarantor  has with Lender,  including  any  agreement  made in
connection  with the signing of this  Agreement;  (b) Borrower or any  guarantor
ceases  doing  business or is  insolvent;  (c) any  guarantor  seeks,  claims or
otherwise attempts to limit, modify or revoke such guarantor's guarantee of this
Agreement or any other loan with Lender; (d) Borrower has applied funds provided
pursuant to this Agreement for purposes  other than those  authorized by Lender;
or (e) Lender in good faith deems itself  insecure  under this  Agreement or any
other agreement between Lender and Borrower.

CONTINUING VALIDITY. Except as expressly changed by this Agreement, the terms of
the original  obligation or obligations,  including all agreements  evidenced or
securing  the  obligation(s),  remain  unchanged  and in full force and  effect.
Consent  by Lender to this  Agreement  does not waive  Lender's  right to strict
performance of the  obligation(s)  as changed,  nor obligate  Lender to make any
future change in terms. Nothing in this Agreement will constitute a satisfaction
of the obligation(s).  It is the intention of Lender to retain as liable parties
all makers and endorsers of the original obligation(s),  including accommodation
parties, unless a party is expressly released by Lender in writing. Any maker or
endorser, including accommodation makers, will not be released by virtue of


<PAGE>



this Agreement.  If any person who signed the original  obligation does not sign
this  Agreement  below,  then all persons  signing below  acknowledge  that this
Agreement is given conditionally, based on the representation to Lender that the
non-signing  party  consents to the changes and  provisions of this Agreement or
otherwise  will not be  released  by it.  This  waiver  applies  not only to any
initial  extension,  modification  or release,  but also to all such  subsequent
actions.

PURPOSE OF LOAN. Working Capital.

YEAR 2000.  Borrower has reviewed  and  assessed  its  business  operations  and
computer  systems and  applications to address the "year 2060 problem" (that is,
that  computer  applications  and  equipment  used  by  Borrower,   directly  or
indirectly   through  third   parties,   may  be  unable  to  properly   perform
date-sensitive  functions  before,  during and after January 1, 2000).  Borrower
reasonably  believes  that the year 2000  problem  will not result in a material
adverse  change in  Borrower's  business  condition  (financial  or  otherwise),
operations, properties or prospects or ability to repay Lender. Borrower




<PAGE>



06-01-1999                           CHANGE IN TERMS AGREEMENT
                             Page 2 (Continued)

          Loan NO 34
agrees that this representation will be true and correct on
and shall be deemed  made by Borrower on each date  Borrower  requests  any
advance under this Agreement or Note or delivers any information to Lender.
Borrower will promptly deliver to Lender such information  relating to this
representation as Lender requests from time to time.

PRIOR NOTE. #34.

MISCELLANEOUS PROVISIONS.  Lender may delay or forgo enforcing any of its rights
or remedies  under this Agreement  without  losing them.  Borrower and any other
person who signs,  guarantees or endorses this Agreement,  to the extent allowed
by law, waive presentment,  demand for payment,  protest and notice of dishonor.
Upon any change in the terms of this Agreement,  and unless otherwise  expressly
stated  in  writing,  no party  who  signs  this  Agreement,  whether  as maker,
guarantor,  accommodation  maker or endorser,  shall be released from liability.
All such parties agree that Lender may renew or extend  (repeatedly  and for any
length of time) this loan, or release any party or guarantor or  collateral;  or
impair,  fail to  realize  upon or perfect  Lender's  security  Interest  in the
collateral;  and take any other action  deemed  necessary by Lender  without the
consent  of or notice to anyone.  All such  parties  also agree that  Lender may
modify this loan without the consent of or notice to anyone other than the party
with whom the modification is made.

PRIOR TO SIGNING THIS  AGREEMENT,  BORROWER READ AND UNDERSTOOD ALL TH RO ISIONS
OF THIS  AGREEMENT  INCLUDING THE VARIABLE  INTEREST RATE  PROVISIONS.  BORROWER
AGREES TO THE TE S 0 THE AGREEMENT AND ACKNOWLEDGES  RECEIPT OF A COMPLETED COPY
OF THE AGREEMENT.

BORROWER

Advanced Business Sciences,. Inc.

By:                                            By:
   Benjamin J. Lamb, President & CEO         Rob Rasmussen, Secretary

By:                                            By:
   John Gaukel, Vice President R & D          Roger Kanne, Treasurer






<PAGE>



                          NOTICE OF FINAL AGREEMENT

Principal   Loan Date  Maturity Loan No. Call   Collateral        Account
     Officer          Initials
$1,000,000.00  08-15-1999         34             3886         1735062078
  MEE08
     References  in the shaded area are for  Lender's  use only and do not limit
the applicability of this document to any particular loan or item.

Borrower:  Advanced Business Sciences, Inc. Lender:
           U.S. Bank National Association
           3345 N. 107th Street                  88th & Center
           Omaha, NE 68134                       8800 West Center Road
                                                 Omaha, NE 68124

          NOTICE - WRITTEN AGREEMENTS.  A credit agreement must be in writing to
     be  enforceable  under  Nebraska  law.  To  protect  you  and us  from  any
     misunderstandings or disappointments, any contract, promise, undertaking or
     offer  to  forbear  repayment  of  money  or to make  any  other  financial
     accommodation  in connection  with this loan of money or grant or extension
     of credit, or any amendment of, cancellation of, waiver of, or substitution
     for any or all of the terms or  provisions  of any  instrument  or document
     executed in  connection  with this loan of money or grant or  extension  of
     credit      must      be     in      writing      to     be      effective.
     ---------------------------------------------------------------------------
     --------------------

By signing this document each Party  represents and agrees that: (a) The written
Loan Agreement represents the final agreement between the Parties, (b) There are
no  unwritten  oral  agreements  between the  Parties,  and (c) The written Loan
Agreement may not be contradicted by evidence of any prior, contemporaneous,  or
subsequent oral agreements or understandings of the Parties.

As used In this Notice, the following terms have the following meanings:

          Loan. The term "Loan" means the following  described  loan: a Variable
     Rate (2.000% over U.S. Bank National Association  Reference Rate, making an
     initial rate of 9.750%),  Nondisclosable Revolving Line of Credit Loan to a
     Corporation  for  $1,000,000.00  due on August 15, 1999.  This is a secured
     renewal of the following described indebtedness: #34.


<PAGE>




Parties. The term "Parties" means U.S. Bank National Association and any and all
entities or  individuals  who are  obligated  to repay the loan or have  pledged
property as security for the Loan, including without limitation the following:

Borrower:           Advanced Business Sciences, Inc.
Guarantor:          Roger J. Kanne, James L. Pietig, Dennis L. Anderson,
                    Mary M. Collison, Robert Badding, Martin J. Halbur, DDS,
                    Ronald W. Muhlbauer, James C. DiPrima, John J. Gaukel and
                    Robin L. Rasmussen

Loan Agreement. The term "Loan Agreement" means one or more promises, promissory
notes, agreements,  undertakings,  security agreements,  deeds of trust or other
documents,  or  commitments,  or any  combination of those actions or documents,
relating to the Loan, including without limitation the following:

                               NECESSARY FORMS

Promissory Note / Change In Terms Agr.            Commercial Guaranty
Security Agreement                                UCC - 1
Disbursement Request and Authorization            Notice of Final Agreement

                                     OPTIONAL FORMS
Amortization Schedule






<PAGE>



06-01-1999                        NOTICE OF FINAL AGREEMENT
                                           Page 2
Loan NO 34                               (Continued)

Each  Party  who  signs  below,  other  than  U.S.  Bank  National  Association,
acknowledges,  r represents and warrants to U.S. Bank National  Association that
It has received, read and understood this Notice of Final Agreement. This Notice
Is dated June 1, 1999.

BORROWER:

Advanced Business Sciences Inc.

By:                                                 By:
_____________________________
       Benjamin  J. Lamb, President & CEO         Rob Rasmussen, Secretary

By:  ______________________________                                         By:
- ----------------------------------------
John Gaukel, Vice President R & D                      Roger Kanne, Treasurer


GUARANTOR:

Roger J. Kanne

James Pletlg

Dennis L Anderson

Mary M. Collison

Robert Baddling

Martin J. Halbur, DDS

Ronald W. Muhlbauer
                      -
    --,-%
James C DiPrima

John J. Gaukel

Robin L. Rasmussen

LENDER:


<PAGE>




U.S. Bank National Association

By:

Authorized Officer




<PAGE>




          COMMERCIAL  SECURITY  AGREEMENT  Principal Loan Date Maturity Loan No.
     Call  Collateral   Account  Officer   Initials   $1,000,000.00   04-08-1998
     06-01-1999  005281  1735062078  C08  References  in the shaded area are for
     Lender's use only and do not limit the  applicability  of this  document to
     any particular loan or item.  Borrower:  Advanced Business  Sciences,  Inc.
     Lender:  U.S. Bank National  Association 334S N. 107th Street 88th & Center
     Omaha,  NE 68134 8800 West Center  Road,  Omaha,  NE 68124 THIS  COMMERCIAL
     SECURITY AGREEMENT is entered Into between Advanced Business Sclences, Inc.
     (referred  to  below as  "Grantor");  and U.S.  Bank  National  Association
     (referred to below as "Lender"). For valuable consideration, Grantor grants
     to Lender a security  Interest In the Collateral to secure the Indebtedness
     and agrees that Lender shall have the rights stated In this  Agreement with
     respect to the Collateral, In addition to all other rights which Lender may
     have by law.  DEFINITIONS.  The  following  words shall have the  following
     meanings when used in this Agreement.  Terms not otherwise  defined in this
     Agreement  shall have the meanings  attributed to such terms in the Uniform
     Commercial  Code.  All  references to dollar  amounts shall mean amounts in
     lawful  money  of  the  United  States  of  America.  Agreement.  The  word
     "Agreement" means this Commercial  Security  Agreement,  as this Commercial
     Security  Agreement may be amended or modified from time to time,  together
     with all  exhibits  and  schedules  attached  to this  Commercial  Security
     Agreement from time to time.  Collateral.  The word "Collateral"  means the
     following  described  property of Grantor,  whether now owned or  hereafter
     acquired, whether now existing or hereafter arising, and wherever located:

       All Inventory, chattel paper, accounts, equipment and general Intangibles

       In addition,  the word "Collateral"  includes all the following,  whether
now owned or hereafter acquired, whether now existing or
       hereafter arising, and wherever located:

          (a) All attachments,  accessions, accessories, tools, parts, supplies,
increases, and additions to and all replacements of and substitutions for
          any property described above.
          (b) All products and produce of any of the property  described in this
          Collateral   section.   (c)   All   accounts,   general   intangibles,
          instruments, rents, monies, payments, and all other rights,
arising out of a sale, lease, or other disposition
           of any of the property described in this Collateral section.


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         (d)  All  proceeds  (including   insurance  proceeds)  from  the  sale,
destruction, loss, or other disposition of any of the property described in this
          Collateral section.
          (e) All records and data relating to any of the property  described in
this  Collateral  section,  whether  in  the  form  of  a  writing,  photograph,
microfilm,
           microfiche,  or  electronic  media,  together  with all of  Grantor's
right,  title, and interest in and to all computer software required to utilize,
create,
           maintain, and process any such records or data on electronic media.

          Event of  Default.  The words  "Event  of  Default"  mean and  include
     without  limitation  any of the  Events of Default  set forth  below in the
     section titled "Events of Default."

          Grantor.  The word "Grantor" means Advanced Business  Sciences,  Inc.,
     its successors and
assigns

          Guarantor.  The word "Guarantor' means and includes without limitation
     each and all of the guarantors'.  sureties,  and  accommodation  parties in
     connection with the Indebtedness.

          Indebtedness. The word "Indebtedness" means the indebtedness evidenced
     by the Note, including all principal and interest,  together with all other
     indebtedness and costs and expenses for which Grantor is responsible  under
     this Agreement or under any of the Related Documents.

          Lender.  The word "Lender" means U.S. Bank National  Association,  its
     successors and assigns.

          Note. The word "Note" means the note or credit  agreement  dated April
     8, 1998, in the principal  amount of $1,000,000.00  from Advanced  Business
     Sciences,  Inc. to Lender,  together with all renewals of,  extensions  of,
     modifications of, refinancings of,  consolidations of and substitutions for
     the note or credit agreement. I

          Related  Documents.  The words "Related  Documents"  mean' and include
     without   limitation  all  promissory  notes,   credit   agreements,   loan
     agreements,  environmental  agreements,  guaranties,,  security agreements,
     mortgages,  deeds of  trust,  and all  other  instruments,  agreements  and
     documents,  whether now or hereafter existing,  executed in connection with
     the Indebtedness.

RIGHT OF SETOFF. Grantor hereby grants Lender A contractual security interest in
and hereby assigns, conveys,  delivers,  pledges, and transfers all of Grantor's
right,  title and interest in and to  Grantor's  accounts  with Lender  (whether
checking,  savings, or some other account),  including all accounts held jointly
with someone else and all  accounts  Grantor may open in the future,  excluding,
however, all IRA and Keogh accounts,  and all trust accounts for which the grant
of a security


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interest would be prohibited by law. Grantor  authorizes  Lender,  to the extent
permitted by applicable  law, to charge or setoff all  Indebtedness  against any
and all such accounts.

OBLIGATIONS OF GRANTOR. Grantor warrants and covenants to Lender as follows:

Organization.  Grantor  is  a  corporation  which  is  duly  organized,  validly
existing,  and in  good  standing  under  the  laws  of the  state  of  Grantors
incorporation.  Grantor has its chief executive  office at 3345 N. 107th Street,
Omaha,  NE 68134.  Grantor  will notify  Lender of any change in the location of
Grantor's chief executive office.

Authorization.  The execution,  delivery,  and  performance of this Agreement by
Grantor have been duly authorized by all necessary  action by Grantor and do not
conflict  with,  result in a violation of, or constitute a default under (a) any
provision of its articles of incorporation or  organization,  or bylaws,  or any
agreement or other instrument binding upon Grantor or (b) any law,  governmental
regulation, court decree, or order applicable to Grantor.

Perfection  of  Security  Interest.  Grantor  agrees to execute  such  financing
statements and to take whatever other actions are requested by Lender to perfect
and  continue  Lender's  security  interest in the  Collateral.  Upon request of
Lender,  Grantor will deliver to Lender any and all of the documents  evidencing
or constituting the Collateral, and Grantor will note Lender's interest upon any
and all  chattel  paper if not  delivered  to Lender for  possession  by Lender.
Grantor  hereby  appoints  Lender as its  irrevocable  attorney-in-fact  for the
purpose of  executing  any  documents  necessary  to perfect or to continue  the
security interest granted in this Agreement. Lender may at any time, and without
further  authorization  from  Grantor,  file a  carbon,  photographic  or  other
reproduction  of any  financing  statement  or of  this  Agreement  for use as a
financing  statement.  Grantor  will  reimburse  Lender for all expenses for the
perfection and the continuation of the perfection of Lender's  security interest
in the  Collateral.  Grantor  promptly  will notify  Lender before any change in
Grantor's  name  including any change to the assumed  business names of Grantor.
This Is a continuing  Security Agreement and will continue In effect even though
all or any part of the Indebtedness Is paid In full and even though for a period
of time Grantor may not be Indebted to Lender.

No Violation.  The execution and delivery of this Agreement will not Violate any
law or  agreement  governing  Grantor or to which  Grantor  is a party,  and its
certificate or articles of Incorporation  and bylaws do not prohibit any term or
condition of this Agreement.

Enforceability of Collateral. To the extent the Collateral consists of accounts,
chattel  paper,  or  general  intangibles,  the  Collateral  is  enforceable  in
accordance  with its terms,  is  genuine,  and  complies  with  applicable  laws
concerning  form,  content  and manner of  preparation  and  execution,  and all
persons  appearing to be obligated on the Collateral have authority and capacity
to contract and are in fact obligated as they appear to be on the Collateral. At
the time any account becomes subject to a security  interest in favor of Lender,
the account shall be a good and valid account  representing an undisputed,  bona
fide indebtedness  incurred by the account debtor,  for merchandise held subject
to delivery  instructions  or  theretofore  shipped or  delivered  pursuant to a
contract of sale, or for services  theretofore  performed by Grantor with or for
the account debtor;


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there  shall be no setoffs or  counterclaims  against any such  account;  and no
agreement under which any deductions or discounts may be claimed shall have been
made with the account debtor except those disclosed to Lender in writing.

Location of the  Collateral.  Grantor,  upon request of Lender,  will deliver to
Lender  in form  satisfactory  to  Lender  a  schedule  of real  properties  and
Collateral.  locations  relating  to  Grantor's  operations,  including  without
limitation  the  following:  (a) all real property  owned or being  purchased by
Grantor;  (b) all real  property  being  rented or leased  by  Grantor;  (c) all
storage facilities owned, rented,  leased, or being used by Grantor; and (d) all
other properties where Collateral is or may- be located.  Except in the ordinary
course  of its  business,  Grantor  shall not  remove  the  Collateral  from its
existing locations without the prior written consent of Lender.

          Removal of  Collateral.  Grantor shall keep the  Collateral (or to the
     extent the Collateral consists of intangible property such as accounts, the
     records  concerning the Collateral) at Grantor's address shown above, or at
     such other locations as are acceptable to Lender. Except in the

04-08-1998                 COMMERCIAL SECURITY AGREEMENT
                           Page 2
Loan No 005281                           (Continued)
- ------------------------------------------------------------------------------
- ------------
ordinary course of its business, including the sales of inventory, Grantor shall
not remove the Collateral from its existing  locations without the prior written
consent of Lender.  To the extent that the Collateral  consists of vehicles,  or
other titled  property,  Grantor shall not take or permit any action which would
require application for certificates of title for the vehicles outside the State
of Nebraska, without the prior written consent of Lender. Transactions Involving
Collateral.  Except for  inventory  sold or accounts  collected  in the ordinary
course  of  Grantor's  business,  Grantor  shall  not  sell,  offer to sell,  or
otherwise transfer or dispose of the Collateral. While Grantor is not in default
under this  Agreement,  Grantor  may sell  inventory,  but only in the  ordinary
course of its business and only to buyers who qualify as a buyer in the ordinary
course of business. A sale in the ordinary course of Grantor's business does not
include a transfer in partial or total  satisfaction of a debt or any bulk sale.
Grantor shall not pledge, mortgage,  encumber or otherwise permit the Collateral
to be subject to any lien, security interest, encumbrance, or charge, other than
the security interest provided for in this Agreement,  without the prior written
consent of Lender.  This includes security  interests even if junior in right to
the security  interests  granted under this Agreement.  Unless waived by Lender,
all proceeds from any disposition of the Collateral (for whatever  reason) shall
be held in trust for Lender and shall not be  commingled  with any other  funds;
provided however, this requirement shall not constitute consent by Lender to any
sale or other disposition.  Upon receipt,  Grantor shall immediately deliver any
such proceeds to Lender.  Title.  Grantor represents and warrants to Lender that
it holds  good and  marketable  title to the  Collateral,  free and clear of all
liens and  encumbrances  except  for the lien of this  Agreement.  No  financing
statement  covering any of the  Collateral is on file in any public office other
than those which reflect the security  interest  created by this Agreement or to
which Lender has specifically consented. Grantor shall defend Lender's rights in
the Collateral against the claims and demands of all other persons.


<PAGE>



Collateral  Schedules  and  Locations.  As often as Lender  shall  require,  and
insofar as the Collateral consists of accounts and general intangibles,  Grantor
shall deliver to Lender schedules of such Collateral, including such information
as Lender may  require,  including  without  limitation  names and  addresses of
account debtors and agings of accounts and general  intangibles.  Insofar as the
Collateral consists of inventory and equipment, Grantor shall deliver to Lender,
as often as Lender shall require, such lists, descriptions,  and designations of
such  Collateral  as Lender may require to  identify  the  nature,  extent,  and
location of such Collateral. Such information shall be submitted for Grantor and
each of its  subsidiaries  or related  companies.  Maintenance and Inspection of
Collateral. Grantor shall maintain all tangible Collateral in good condition and
repair.  Grantor  will not  commit or permit  damage  to or  destruction  of the
Collateral  or  any  part  of  the   Collateral.   Lender  and  its   designated
representatives  and  agents  shall  have the right at all  reasonable  times to
examine,  inspect,  and audit the  Collateral  wherever  located.  Grantor shall
immediately  notify  Lender  of  all  cases  involving  the  return,  rejection,
repossession,  loss or damage of or to any Collateral; of any request for credit
or adjustment or of any other  dispute  arising with respect to the  Collateral;
and generally of all happenings and events affecting the Collateral or the value
or the amount of the Collateral.  Taxes, Assessments and Liens. Grantor will pay
when due all  taxes,  assessments,  and liens  upon the  Collateral,  its use or
operation, upon this Agreement, upon any promissory note or notes evidencing the
Indebtedness,  or upon any of the other Related Documents.  Grantor may withhold
any such  payment or may elect to  contest  any lien if Grantor is in good faith
conducting an  appropriate  proceeding  to contest the  obligation to pay and so
long as Lender's  interest in the Collateral is not jeopardized in Lender's sole
opinion. If the Collateral is subjected to a lien which is not discharged within
fifteen  (15) days,  Grantor  shall  deposit  with  Lender  cash,  a  sufficient
corporate  surety  bond or other  security  satisfactory  to Lender in an amount
adequate  to provide for the  discharge  of the lien plus any  interest,  costs,
attorneys' fees or other charges that could accrue as a result of foreclosure or
sale of the  Collateral.  In any contest  Grantor shall defend itself and Lender
and shall  satisfy any final adverse  judgment  before  enforcement  against the
Collateral.  Grantor shall name Lender as an additional obligee under any surety
bond  furnished  in  the  contest  proceedings.   Compliance  With  Governmental
Requirements. Grantor shall comply promptly with all laws, ordinances, rules and
regulations  of all  governmental  authorities,  now  or  hereafter  in  effect,
applicable to the ownership, production,  disposition, or use of the Collateral.
Grantor  may contest in good faith any such law,  ordinance  or  regulation  and
withhold  compliance during any proceeding,  including  appropriate  appeals, so
long as  Lender's  interest  in the  Collateral,  in  Lender's  opinion,  is not
jeopardized.  Hazardous  Substances.  Grantor  represents  and warrants that the
Collateral never has been, and never will be so long as this Agreement remains a
lien  on  the  Collateral,  used  for  the  generation,   manufacture,  storage,
transportation,  treatment,  disposal,  release  or  threatened  release  of any
hazardous  waste or substance,  as those terms are defined in the  Comprehensive
Environmental Response,  Compensation, and Liability Act of 1980, as amended, 42
U.S.C.  Section  9601,  et  seq.   ("CERCLA"),   the  Superfund  Amendments  and
Reauthorization  Act of  1986,  Pub.  L.  No.  99-499  ("SARA"),  the  Hazardous
Materials  Transportation  Act, 49 U.S.C.  Section 1801,  et seq.,  the Resource
Conservation  and  Recovery  Act,  42 U.S.C.  Section  6901,  et seq.,  or other
applicable state or Federal laws, rules, or regulations  adopted pursuant to any
of the foregoing.  The terms "hazardous  waste" and "hazardous  substance" shall
also include,  without  limitation,  petroleum and petroleum  by-products or any
fraction  thereof and asbestos.  The  representations  and warranties  contained
herein


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are based on  Grantor's  due  diligence  in  investigating  the  Collateral  for
hazardous  wastes and  substances.  Grantor  hereby (a)  releases and waives any
future claims against Lender for indemnity or  contribution in the event Grantor
becomes  liable for cleanup or other costs under any such laws,  and, (b) agrees
to  indemnify  and hold  harmless  Lender  against any and all claims and losses
resulting from a breach of this provision of this Agreement.  This obligation to
indemnify shall survive the payment of the  Indebtedness and the satisfaction of
this  Agreement.  Maintenance of Casualty  Insurance.  Grantor shall procure and
maintain all risks  insurance,  including  without  limitation  fire,  theft and
liability.  coverage  together  with such other  insurance as Lender may require
with respect to the Collateral, in form, amounts, coverages and basis reasonably
acceptable to Lender and issued by a company or companies reasonably  acceptable
to Lender.  Grantor, upon request of Lender, will deliver to Lender from time to
time the policies or certificates  of insurance in form  satisfactory to Lender,
including  stipulations  that  coverages  will not be  cancelled  or  diminished
without at least ten (10) days' prior written notice to Lender and not including
any  disclaimer  of the  insurer's  liability for failure to give such a notice.
Each insurance policy also shall include an endorsement  providing that coverage
in favor of  Lender  will not be  impaired  in any way by any act,  omission  or
default of Grantor or any other person. In connection with all policies covering
assets in which  Lender  holds or is offered a security  interest,  Grantor will
provide  Lender  with such loss  payable  or other  endorsements  as Lender  may
require.  If Grantor at any time fails to obtain or maintain  any  insurance  as
required under this Agreement, Lender may (but shall not be obligated to) obtain
such insurance as Lender deems  appropriate,  including if it so chooses "single
interest  insurance," which will cover only Lender's interest in the Collateral.
Application of Insurance  Proceeds.  Grantor shall promptly notify Lender of any
loss or damage to the Collateral. Lender may make proof of loss if Grantor fails
to do so within fifteen (15) days of the casualty. All proceeds of any insurance
on the Collateral,  including accrued proceeds thereon,  shall be held by Lender
as part of the  Collateral.  If Lender  consents to repair or replacement of the
damaged or  destroyed  Collateral,  Lender  shall,  upon  satisfactory  proof of
expenditure,  pay or reimburse Grantor from the proceeds for the reasonable cost
of repair or restoration. If Lender does not consent to repair or replacement of
the Collateral,  Lender shall retain a sufficient  amount of the proceeds to pay
all of the  Indebtedness,  and shall pay the  balance to Grantor.  Any  proceeds
which have not been  disbursed  within six (6) months  after  their  receipt and
which Grantor has not committed to the repair or  restoration  of the Collateral
shall be used to prepay the Indebtedness. Insurance Reserves. Lender may require
Grantor to maintain  with Lender  reserves  for payment of  insurance  premiums,
which  reserves  shall be  created  by monthly  payments  from  Grantor of a sum
estimated  by Lender to be  sufficient  to produce,  at least  fifteen (15) days
before the premium due date, amounts at least equal to the insurance premiums to
be paid.  If fifteen  (15) days before  payment is due,  the  reserve  funds are
insufficient,  Grantor  shall upon  demand  pay any  deficiency  to Lender.  The
reserve funds shall be held by Lender as a general deposit and shall  constitute
a  non-interest-bearing  account  which  Lender  may  satisfy  by payment of the
insurance  premiums  required to be paid by Grantor as they  become due.  Lender
does not hold the  reserve  funds in trust for  Grantor,  and  Lender is not the
agent of Grantor for payment of the  insurance  premiums  required to be paid by
Grantor.  The  responsibility for the payment of premiums shall remain Grantor's
sole responsibility.  Insurance Reports.  Grantor, upon request of Lender, shall
furnish to Lender  reports on each  existing  policy of  insurance  showing such
information as Lender may reasonably  request  including the following:  (a) the
name, of the insurer;  (b) the risks insured;  (c) the amount of the policy; (d)
the


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property insured; (e) the then current value on the basis of which insurance has
been obtained and the manner of determining  that value;  and (f) the expiration
date of the policy.  In addition,  Grantor shall upon request by Lender (however
not more often than  annually)  have an independent  appraiser  satisfactory  to
Lender  determine,  as  applicable,  the cash value or  replacement  cost of the
Collateral.
GRANTOR'S RIGHT TO POSSESSION AND TO COLLECT ACCOUNTS. Until default and
except as otherwise  provided  below with respect to accounts,  Grantor may have
possession  of the  tangible  personal  property and  beneficial  use of all the
Collateral  and may use It in any  lawful  manner  not  inconsistent  with  this
Agreement or the Related  Documents,  provided that Grantors fight to possession
and  beneficial use shall not apply to any  Collateral  where  possession of the
Collateral by Lender is required by law to perfect Lender's security interest in
such Collateral.  Until otherwise notified by Lender, Grantor may collect any of
the Collateral  consisting of accounts.  At any time and even though no Event of
Default  exists,  Lender may  exercise its rights to collect the accounts and to
notify account  debtors to make payments  directly to Lender for  application to
the Indebtedness.  Lender at any time has possession of any Collateral,  whether
before or after an Event of Default,  Lender  shall be deemed to have  exercised
reasonable  care in the custody and  preservation  of the  Collateral  if Lender
takes such action for that  purpose as Grantor  shall  request or as Lender,  in
Lender's sole discretion,  shall deem appropriate under the  circumstances,  but
failure to honor any  request  by Grantor  shall not of itself be deemed to be a
failure to exercise  reasonable  care.  Lender shall not be required to take any
steps necessary to preserve any rights in the Collateral  against prior parties,
nor to protect,  preserve or maintain any security  interest given to secure the
Indebtedness. EXPENDITURES BY LENDER. If not discharged or paid when due, Lender
may (but shall not be obligated to) discharge or pay any amounts





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04-08-1998COMMERCIAL SECURITY AGREEMENT
  Page 3
Loan No 005281 (Continued)

required to be  discharged or paid by Grantor  under this  Agreement,  including
without limitation all taxes, liens, security interests, encumbrances, and other
claims,  at any time  levied or placed on the  Collateral.  Lender also may (but
shall  not be  obligated  to)  pay  all  costs  for  insuring,  maintaining  and
preserving the Collateral.  All such expenditures incurred or paid by Lender for
such  purposes  will then bear  interest at the rate charged under the Note from
the date  incurred or paid by Lender to the date of  repayment  by Grantor.  All
such expenses shall become a part of the  Indebtedness  and, at Lender's option,
will (a) be payable on  demand,  (b) be added to the  balance of the Note and be
apportioned  among and be payable  with any  installment  payments to become due
during  either  (I) the  term of any  applicable  insurance  policy  or (ii) the
remaining term of the Note, or (c) be treated as a balloon payment which will be
due and payable at the Note's maturity.  This Agreement also will secure payment
of these  amounts.  Such  right  shall be in  addition  to all other  rights and
remedies to which  Lender may be  entitled  upon the  occurrence  of an Event of
Default.  EVENTS OF DEFAULT.  Each of the following shall constitute an Event of
Default under this  Agreement:  Default on  Indebtedness.  Failure of Grantor to
make any  payment  when due on the  Indebtedness.  Other  Defaults.  Failure  of
Grantor to comply  with or to perform any other  term,  obligation,  covenant or
condition  contained in this Agreement or in any of the Related  Documents or in
any other agreement between Lender and Grantor. False Statements.  Any warranty,
representation  or  statement  made or  furnished  to  Lender by or on behalf of
Grantor  under this  Agreement,  the Note or the Related  Documents  is false or
misleading in any material respect, either now or at the time made or furnished.
Defective  Collateralization.  This  Agreement  or any of the Related  Documents
ceases to be in full  force and  effect  (including  failure  of any  collateral
documents to create a valid and perfected security interest or lien) at any time
and for any reason.  Insolvency.  The  dissolution  or  termination of Grantor's
existence as a going business,  the insolvency of Grantor,  the appointment of a
receiver for any part of Grantor's  property,  any assignment for the benefit of
creditors,  any type of creditor workout,  or the commencement of any proceeding
under any  bankruptcy  or  insolvency  laws by or against  Grantor.  Creditor or
Forfeiture  Proceedings.  Commencement of foreclosure or forfeiture proceedings,
whether by judicial proceeding,  self-help, repossession or any other method, by
any creditor of Grantor or by any governmental  agency against the Collateral or
any other collateral  securing the Indebtedness.  This includes a garnishment of
any of Grantor's  deposit accounts with Lender.  However,  this Event of Default
shall not apply if there is a good faith  dispute by Grantor as to the  validity
or  reasonableness of the claim which is the basis of the creditor or forfeiture
proceeding  and if  Grantor  gives  Lender  written  notice of the  creditor  or
forfeiture  proceeding  and deposits with Lender monies or a surety bond for the
creditor or forfeiture  proceeding,  in an amount  determined by Lender,  in its
sole discretion,  as being an adequate  reserve or bond for the dispute.  Events
Affecting  Guarantor.  Any of the  preceding  events  occurs with respect to any
Guarantor  of any  of  the  Indebtedness  or  such  Guarantor  dies  or  becomes
incompetent.  Lender,  at its option,  may, but shall not be required to, permit
the Guarantor's estate to assume unconditionally the obligations


<PAGE>



arising under the guaranty in a manner satisfactory to Lender, and, in doing so,
cure the Event of Default.  Adverse Change.  A material adverse change occurs in
Grantor's  financial  condition,  or Lender  believes the prospect of payment or
performance of the Indebtedness is impaired.
Insecurity. Lender, in good faith, deems itself insecure.
Right to Cure. If any default, other than a Default on Indebtedness,  is curable
and if  Grantor  has not  been  given a prior  notice  of a  breach  of the same
provision of this Agreement,  it may be cured (and no Event of Default will have
occurred) if Grantor,  after Lender sends written notice  demanding cure of such
default,  (a) cures the default  within  fifteen (15) days;  or (b), if the cure
requires more than fifteen (15) days,  immediately  initiates steps which Lender
deems in  Lender's  sole  discretion  to be  sufficient  to cure the default and
thereafter continues and completes all reasonable and necessary steps sufficient
to produce compliance as soon as reasonably practical.  I RIGHTS AND REMEDIES ON
DEFAULT.  If an  Event of  Default  occurs  under  this  Agreement,  at any time
thereafter,  Lender  shall  have all the  rights  of a secured  party  under the
Nebraska Uniform Commercial Code. In addition and without limitation, Lender may
exercise  any one or more  of the  following  rights  and  remedies:  Accelerate
Indebtedness.  Lender  may  declare  the  entire  Indebtedness,   including  any
prepayment  penalty which Grantor would be required to pay,  immediately due and
payable,  without  notice.  Assemble  Collateral.  Lender may require Grantor to
deliver  to  Lender  all or any  portion  of the  Collateral  and  any  and  all
certificates of title and other documents relating to the Collateral. Lender may
require  Grantor to assemble the Collateral and make it available to Lender at a
place to be  designated  by Lender.  Lender  also shall have full power to enter
upon the property of Grantor to take possession of and remove the Collateral. If
the Collateral contains other goods not covered by this Agreement at the time of
repossession,  Grantor  agrees  Lender may take such other goods,  provided that
Lender makes  reasonable  efforts to return them to Grantor after  repossession.
Sell the Collateral.  Lender shall have full power to sell, lease,  transfer, or
otherwise deal with the  Collateral or proceeds  thereof in its own name or that
of Grantor.  Lender may sell the  Collateral at public  auction or private sale.
Unless the  Collateral  threatens  to decline  speedily in value or is of a type
customarily  sold on a recognized  market,  Lender will give Grantor  reasonable
notice of the time and place of any public sale,  or of the time after which any
private sale or any other intended  disposition of the Collateral is to be made.
The  requirements  of reasonable  notice shall be met if such notice is given at
least ten (10) days  before the time of the sale or  disposition.  All  expenses
relating to the disposition of the Collateral,  including without limitation the
expenses of  retaking,  holding,  insuring,  preparing  for sale and selling the
Collateral-,  shall become a part of the Indebtedness  secured by this Agreement
and shall be  payable  on demand,  with  interest  at the Note rate from date of
expenditure  until  repaid.   Appoint  Receiver.  To  the  extent  permitted  by
applicable  law, Lender shall have the following  rights and remedies  regarding
the  appointment  of a receiver:  (a) Lender may have a receiver  appointed as a
matter of right,  (b) the  receiver  may be an  employee of Lender and may serve
without  bond,  and (c) all fees of the receiver  and his or her attorney  shall
become part of the  Indebtedness  secured by this Agreement and shall be payable
on demand, with interest at the Note rate from date of expenditure until repaid.
Collect Revenues,  Apply Accounts.  Lender, either itself or through a receiver,
may collect the  payments,  rents,  income,  and revenues  from the  Collateral.
Lender may at any time in its discretion  transfer any  Collateral  into its own
name or that of its nominee and receive the payments, rents,


<PAGE>



income,   and  revenues  therefrom  and  hold  the  same  as  security  for  the
Indebtedness  or  apply  it to  payment  of the  Indebtedness  in such  order of
preference  as Lender may  determine.  Insofar  as the  Collateral  consists  of
accounts, general intangibles,  insurance policies, instruments,  chattel paper,
choses in action, or similar property,  Lender may demand, collect, receipt for,
settle, compromise,  adjust, sue for, foreclose, or realize on the Collateral as
Lender may determine, whether or not Indebtedness or Collateral is then due. For
these  purposes,  Lender may, on behalf of and in the name of Grantor,  receive,
open and dispose of mail addressed to Grantor;  change any address to which mail
and payments are to be sent; and endorse notes,  checks,  drafts,  money orders,
documents of title,  instruments and items pertaining to payment,  shipment,  or
storage of any Collateral.  To facilitate collection,  Lender may notify account
debtors and  obligors on any  Collateral  to make  payments  directly to Lender.
Obtain  Deficiency.  If  Lender  chooses  to sell any or all of the  Collateral,
Lender may obtain a judgment against Grantor for any deficiency remaining on the
Indebtedness  due to Lender after  application of all amounts  received from the
exercise of the rights provided in this Agreement. Grantor shall be liable for a
deficiency  even if the  transaction  described in this  subsection is a sale of
accounts or chattel paper. Other Rights and Remedies.  Lender shall have all the
rights and remedies of a secured  creditor  under the  provisions of the Uniform
Commercial Code, as may be amended from time to time. In addition,  Lender shall
have and may exercise any or all other rights and remedies it may have available
at law, in equity, or otherwise. Cumulative Remedies. All of Lender's rights and
remedies, whether evidenced by this Agreement or the Related Documents or by any
other  writing,   shall  be  cumulative  and  may  be  exercised  singularly  or
concurrently.  Election by Lender to pursue any remedy shall not exclude pursuit
of any other remedy,  and an election to make  expenditures or to take action to
perform an obligation of Grantor under this Agreement,  after Grantor's  failure
to perform, shall not affect Lender's right to declare a default and to exercise
its remedies.  MISCELLANEOUS PROVISIONS.  The following miscellaneous provisions
are a part of this  Agreement:  Amendments.  This  Agreement,  together with any
Related  Documents,  constitutes the entire  understanding  and agreement of the
parties as to the  matters  set forth in this  Agreement.  No  alteration  of or
amendment  to this  Agreement  shall be  effective  unless  given in writing and
signed by the party or parties  sought to be charged or bound by the  alteration
or amendment.  Applicable  Law. This  Agreement has been delivered to Lender and
accepted  by Lender in the State of  Nebraska.  If there is a  lawsuit,  Grantor
agrees upon Lender's  request to submit to the jurisdiction of the courts of the
State  of  Nebraska.  This  Agreement  shall be  governed  by and  construed  in
accordance with the laws of the State of Nebraska.  Attorneys'  Fees;  Expenses.
Grantor agrees to pay upon demand all of Lender's costs and expenses,  including
attorneys'  fees and Lender's legal  expenses,  incurred in connection  with the
enforcement of this Agreement.  Lender may pay someone else to help enforce this
Agreement,  and Grantor  shall pay the costs and  expenses of such  enforcement.
Costs and expenses include  Lender's  attorneys' fees and legal expenses whether
or not there is a lawsuit,  including  attorneys'  fees and legal  expenses  for
bankruptcy  proceedings (and including efforts to modify or vacate any automatic
stay or  injunction),  appeals,  and any  anticipated  post-judgment  collection
services. Grantor also shall pay all court costs




<PAGE>








04-08-1998                     COMMERCIAL SECURITY AGREEMENT
                                          Page 4
Loan No 005281                          (Continued)


and such additional fees as may be directed by the court.

          Caption   Headings.   Caption  headings  in  this  Agreement  are  for
     convenience purposes only and are not to be used to interpret or define the
     provisions of this Agreement.

Multiple  Parties;  Corporate  Authority.  All obligations of Grantor under this
Agreement  shall be joint and several,  and all references to Grantor shall mean
each and every  Grantor.  This means that each of the persons  signing  below is
responsible for all obligations in this Agreement.

Notices. All notices required to be given under this Agreement shall be given in
writing,  may be sent by telefacsimile  (unless otherwise  required by law), and
shall be effective  when actually  delivered or when deposited with a nationally
recognized  overnight  courier or  deposited in the United  States  mail,  first
class, postage prepaid, addressed to the party to whom the notice is to be given
at the address  shown above.  Any party may change its address for notices under
this Agreement by giving formal written notice to the other parties,  specifying
that the purpose of the notice is to change the party's  address.  To the extent
permitted by  applicable  law, if there is more than one Grantor,  notice to any
Grantor will constitute  notice to all Grantors.  For notice  purposes,  Grantor
will keep Lender informed at all times of Grantor's current address(es).

Power of  Attorney.  Grantor  hereby  appoints  Lender  as its  true and  lawful
attorney-in-fact,  irrevocably,  with  full  power  of  substitution  to do  the
following:  (a) to demand,  collect,  receive,  receipt for, sue and recover all
sums of money or other property which may now or hereafter  become due, owing or
payable  from the  Collateral;  (b) to  execute,  sign and  endorse  any and all
claims, instruments,  receipts, checks, drafts or warrants issued in payment for
the Collateral; (c) to settle or compromise any and all claims arising under the
Collateral,  and, in the place and stead of Grantor,  to execute and deliver its
release and settlement for the claim;  and (d) to file any claim or claims or to
take any action or institute or take part in any proceedings,  either in its own
name or in the name of Grantor, or otherwise,  which in the discretion of Lender
may seem to be necessary or  advisable.  This power is given as security for the
Indebtedness, and the authority hereby conferred is and shall be irrevocable and
shall remain in full force and effect until renounced by Lender.

Severability.  If a court of competent  jurisdiction finds any provision of this
Agreement to be invalid or unenforceable as to any person or circumstance,  such
finding shall not render that provision invalid or unenforceable as to any other
persons or  circumstances.  If feasible,  any such offending  provision shall be
deemed to be modified  to be within the limits of  enforceability  or  validity;
however, if the offending provision cannot be so modified,  it shall be stricken
and all other  provisions of this  Agreement in all other  respects shall remain
valid and enforceable.



<PAGE>



Successor  Interests.  Subject to the limitations set forth above on transfer of
the Collateral, this Agreement shall be binding upon and inure to the benefit of
the parties, their successors and assigns.

Waiver.  Lender  shall  not be deemed  to have  waived  any  rights  under  this
Agreement unless such waiver is given in writing and signed by Lender.  No delay
or omission  on the part of Lender in  exercising  any right shall  operate as a
waiver of such right or any other  right.  A waiver by Lender of a provision  of
this  Agreement  shall not  prejudice or  constitute a waiver of Lender's  right
otherwise to demand strict compliance with that provision or any other provision
of this Agreement.  No prior waiver by Lender, nor any course of dealing between
Lender and Grantor,  shall  constitute a waiver of any of Lender's  rights or of
any of Grantor's obligations as to any future transactions. Whenever the consent
of Lender is required  under this  Agreement,  the  granting of such  consent by
Lender in any instance  shall not  constitute  continuing  consent to subsequent
instances  where such  consent is required  and in all cases such consent may be
granted or withheld in the sole discretion of Lender.

GRANTOR ACKNOWLEDGES HAVING READ ALL THE PROVISIONS OF THIS
COMMERCIAL SECURITY AGREEMENT, AND GRANTOR AGREES TO ITSJERMS. THIS
AGREEMENT IS DATED APRIL 8, 1998.

GRANTOR:

Advanced Business Sciences, Inc.

By:   ______________________________ By:  __________________________________
       Ron Muhlbauer, President         Rob Rasmussen, Chief Operating Officer

By:  ______________________________  By:
      John Gaukel, Vice President R & D         Roger  Kanne, Treasurer



LENDER:

U.S. Bank National Association

By:  ______________________________
       Authorized Officer






                                LOAN AGREEMENT


      This  Loan  Agreement  (this  "Agreement"),  dated as of this  30th day of
April,  1999,  by and  between  Advanced  Business  Sciences,  Inc.,  a Delaware
corporation,, with its principal place of business and chief executive office at
3345 No. 107th  Street,  Omaha,  Nebraska  68134 (the  "Borrower"),  and Mary M.
Collison  residing at 640 Hidden  Valley Road,  Carroll,  Iowa  51401-3205  (the
"Lender").

      WHEREAS, in order to provide funds to the Borrower for working capital and
other  purposes,  the  Borrower  desires to borrow up to Five  Hundred  Thousand
Dollars  ($500,000) from the Lender, and the Lender is willing to make a loan to
the Borrower of such amount, upon the terms and conditions set forth herein;

      NOW THEREFORE,  in  consideration  of the terms and  conditions  contained
herein,  and of any loans or extensions of credit  heretofore,  now or hereafter
made to or for the benefit of the  Borrower by the  Lender,  the parties  hereto
hereby agree as follows:

      1.    DEFINITIONS.

      1.1   General Terms.  When used herein, the following terms shall have the
following meanings:

      "Affiliate" shall mean any Person (a) that directly or indirectly, through
one or more  intermediaries,  controls or is  controlled  by, or is under common
control with a Person, including, without limitation, the officers and directors
of such Person,  (b) that directly or beneficially  owns or holds 20% or more of
any equity interest in such Person,  excluding the Lender, or (c) 20% or more of
whose voting stock (or in the case of a Person which is not a  corporation,  20%
or more of any equity interest) is owned directly or beneficially or held by the
Affiliate. As used herein, the term "control" shall mean possession, directly or
indirectly,  of the power to direct  the  management  or  policies  of a Person,
whether through ownership of securities or otherwise.

      "Assets"  shall mean  assets  reflected  on a balance  sheet  prepared  in
accordance  with  Generally   Accepted   Accounting   Principles,   except  that
investments in or monies due from any Affiliate shall be excluded therefrom.

      "Business  Day" shall mean any day other than a Saturday,  Sunday or other
day on which banks in Omaha, Nebraska, are authorized or required to be closed.

      "Default"  shall mean an event  which  through  the passage of time or the
service of notice or both would mature into an Event of Default.

      "Default  Rate"  shall  mean a rate of  interest  per  annum  equal to the
Regular Rate plus five percent.



<PAGE>



      "Event of Default"  shall mean the  occurrence  or existence of any one or
more  of the  following  events:  (a)  the  Borrower  fails  to  pay  any of its
"Obligations"  hereunder  upon  demand or when such  Obligations  are due or are
declared due; (b) the Borrower fails or neglects to perform, keep or observe any
of the covenants,  conditions or agreements  contained in any of the subsections
of this Agreement or in any of the other ; or (c) any warranty or representation
now or  hereafter  made by the  Borrower in  connection  with this  Agreement is
untrue or incorrect  in any  material  respect,  or any  schedule,  certificate,
statement,  report,  financial data, notice, or writing furnished at any time by
the Borrower to the Lender is untrue or incorrect in any material respect, as of
the date on which the  warranty,  representation  or the facts set forth therein
are stated, certified or deemed made.

      "Generally Accepted  Accounting  Principles" shall mean, as of the date of
any determination with respect thereto, generally accepted accounting principles
as  used  by the  Financial  Accounting  Standards  Board  and/or  the  American
Institute of Certified Public Accountants,  consistently  applied and maintained
throughout the periods indicated.

      "Indebtedness"  shall mean at a  particular  time,  (a)  indebtedness  for
borrowed  money or for the  deferred  purchase  price of property or services in
respect of which the Borrower is liable,  contingently or otherwise,  as obligor
or otherwise or any commitment by which the Borrower  assures a creditor against
loss, including contingent reimbursement  obligations with respect to letters of
credit,  (b)  indebtedness  guaranteed in any manner by the Borrower,  including
guaranties  in  the  form  of an  agreement  to  repurchase  or  reimburse,  (c)
obligations  under leases which shall have been or should be, in accordance with
Generally Accepted Accounting Principles,  recorded as capital leases in respect
of which  obligations  the Borrower is liable,  contingently  or  otherwise,  as
obligor, guarantor or otherwise, or in respect of which obligations the Borrower
assures a creditor against loss, and (d) any unfunded obligation of the Borrower
to a "multiemployer  plan" as such term is defined under the Employee Retirement
Income Security Act of 1974, as amended ("ERISA").

      "Liabilities" shall have the meaning usually given that term in accordance
with Generally Accepted Accounting Principles, and shall include Indebtedness.

      "Line of Credit" shall have the meaning ascribed thereto at subsection 2.1
hereof.

      "Note"   shall  mean  a   promissory   note  issued  by  the  Borrower  in
substantially the form of Exhibit "A" hereto.

      "Obligations"  shall mean all of the Borrower's  obligations,  liabilities
and  indebtedness to the Lender and/or to any Affiliate of the Lender of any and
every kind and nature arising or existing under this  Agreement,  whether now or
hereafter  owing,  arising,  due or payable and  howsoever  evidenced,  created,
incurred,  acquired,  or owing, whether primary,  secondary,  direct,  indirect,
contingent, fixed or otherwise (including obligations of performance).

      "Person"  shall mean any  individual,  sole  proprietorship,  partnership,
joint venture, trust,  unincorporated  organization,  association,  corporation,
institution,  entity,  party, or government (whether national,  federal,  state,
provincial, county, city, municipal or otherwise, including, without limitation,
any instrumentality, division, agency, body or department thereof).


<PAGE>




      "Plan" shall mean any employee  benefit or other plan  maintained  for the
employees of the  Borrower or to which the  Borrower is obligated to  contribute
and subject to Title IV of ERISA.

      "Regular  Rate" shall mean a rate of interest per annum equal to the prime
rate of interest from time to time  established by First Star Bank of Iowa, N.A.
plus 25 basis points.

      1.2 Accounting  Terms.  Any accounting  terms used in this Agreement which
are not specifically  defined herein shall have the meanings  customarily  given
them in accordance with Generally Accepted Accounting Principles.

      1.3 Other Terms Defined in Nebraska  Uniform  Commercial  Code.  All other
terms  contained in this  Agreement  (and which are not  otherwise  specifically
defined herein) shall have the meanings provided in the Uniform  Commercial Code
of the State of Nebraska (the "Code") to the extent the same are used or defined
therein.

      1.4 Effective Date. All references to "the date hereof," "the date of this
Agreement,"  "the effective  date hereof,"  "effective as of the date hereof" or
"of even date  herewith"  contained  herein  or in the other  shall be deemed to
refer to the day and year first above written.

      2.    CREDIT.

      2.1 Line of Credit.  Subject to the terms and conditions herein set forth,
Lender  agrees to advance  funds to Borrower  upon its request from time to time
beginning  on the date  hereof and  terminating  on January  31,  2000,  in such
amounts as the Borrower may from time to time request, in increments of not less
than Ten  Thousand  Dollars  ($10,000),  up to but not  exceeding  Five  Hundred
Thousand  Dollars  ($500,000)  at any time  outstanding  (the "Line of Credit").
Borrower  may reborrow any advance once such advance has been repaid in whole or
in part.

      2.2   Interest.

      (a) So long as no Event of Default has  occurred  and is  continuing,  the
Borrower shall pay to the Lender interest on the outstanding  principal  balance
of the Obligations at the Regular Rate.

      (b) Upon  delivery of written  notice by the Lender to the Borrower of the
occurrence of an Event of Default, the Borrower shall pay to the Lender interest
from the date of such Event of Default to and including the date of cure of such
Event of Default on the outstanding  principal balance of the Obligations at the
Default Rate applicable to such Obligations.

      2.3 Method of Making Payments.  All payments to be made by the Borrower to
the Lender  hereunder shall be made to the Lender at its address set forth above
not later than 12:00 noon Omaha time on the date when due in lawful money of the
United States of America and immediately available funds.

      2.4 Term of this Agreement. This Agreement shall be effective until all of
the obligations  under this Agreement have been finally paid in full;  provided,
that even after full and final payment


<PAGE>



of all Obligations hereunder,  the Borrower's Obligation to indemnify the Lender
in accordance with the terms hereof shall continue.

      2.5 Payment Dates and Basis of  Calculation.  Any payment due hereunder on
any day other than a Business Day shall be due on the next  succeeding  Business
Day, and if such payment shall bear interest in  accordance  herewith,  interest
shall  accrue to the date of  payment.  All  interest  and fees  (other than the
prepayment  fee) shall be computed (on a daily basis) on the basis of a 360- day
year for the actual number of days elapsed.

      2.6 Additional  Consideration.  As additional  consideration  for entering
into this  Agreement,  the Borrower shall issue to the Lender 83,333 fully paid,
nonassessable  shares of  Borrower's  common  stock,  together with a warrant to
purchase  83,333  shares of such common stock at an exercise  price of $1.00 per
share, exercisable at any time on or before October 31, 2000.

      3.    CONDITIONS TO FUNDING OF LINE OF CREDIT.

      The advance of funds under the Line of Credit  shall be  conditioned  upon
the matters set forth  below,  the  delivery of the  following  documents to the
Lender,  in form and substance  satisfactory to the Lender,  and consummation of
all of the  transactions or the  satisfaction of each condition  contemplated by
each such document.

      3.1   Warranties   and   Representations.   All  of  the   warranties  and
representations  of the Borrower  contained  herein shall be true and correct in
all material respects on and as of the date hereof.

      3.2 No Default.  As  determined  by the  Lender,  neither a Default nor an
Event of Default  shall have occurred and be continuing or will result from such
advance.

      3.3 No  Litigation.  There shall be (i) no  litigation,  investigation  or
proceeding pending or threatened against the Borrower or any officer,  director,
or  executive  (as  applicable)  of the  Borrower  (A) in  connection  with this
Agreement  which,  in the sole opinion of the Lender,  is deemed material or (B)
which, if adversely determined, would, in the sole opinion of the Lender, have a
material  adverse  effect on the financial  condition,  business,  or results of
operations of the Borrower;  and (ii) no injunction,  writ, restraining order or
other  order  of any  nature  materially  adverse  to  the  Borrower  issued  or
threatened by any court or governmental agency.

      4.  WARRANTIES.

      The Borrower  represents  and warrants and covenants and agrees that as of
the date of the  execution  of this  Agreement,  and  continuing  so long as any
Obligations  remain  outstanding,  and  (even if there  shall be no  Obligations
outstanding) so long as this Agreement remains in effect:

      4.1  Existence.  The Borrower is a  corporation  duly  organized,  validly
existing  and in good  standing  in the  State  of  Delaware.  The  Borrower  is
qualified to transact business as a foreign


<PAGE>



corporation  in, and is in good standing  under the laws of, all states in which
the Borrower is required by applicable  law to maintain such  qualification  and
good standing.

      4.2 Authority.  The Borrower has full power,  authority and legal right to
enter into this  Agreement.  The  execution and delivery by the Borrower of this
Agreement:  (i) have been duly authorized by all necessary action on the part of
the Borrower  (including  any  required  stockholders  action);  (ii) are not in
contravention of the terms of the Borrower's Articles of Incorporation or Bylaws
or of any  indenture,  agreement or undertaking to which the Borrower is a party
or by which the Borrower or any of its property is bound;  (iii) do not and will
not require any governmental consent,  registration or approval; (iv) do not and
will not contravene any  contractual  or  governmental  restriction to which the
Borrower or any of its  property  may be  subject;  and (v) do not and will not,
except as  contemplated  herein,  result in the imposition of any lien,  charge,
security  interest or  encumbrance  upon any property of the Borrower  under any
existing indenture,  mortgage,  deed of trust, loan or credit agreement or other
material  agreement or  instrument  to which the Borrower is a party or by which
the Borrower or any of its  property may be bound or affected.  The Borrower has
the full  corporate  authority  to own or lease and operate its  property and to
conduct the business in which it is  currently  engaged and in which it proposes
to engage.

      4.3 Binding Effect. This Agreement has been duly executed and delivered or
filed,  as  applicable,  by  the  Borrower,  is the  legal,  valid  and  binding
obligations  of  the  Borrower  and  is  enforceable  against  the  Borrower  in
accordance with their terms.

      4.4 Place of Business.  As of the execution hereof, the principal place of
business  and chief  executive  office of the  Borrower  is at 3345 North  107th
Street, Omaha, Nebraska 68134

      4.5 Survival of Warranties.  All representations and warranties  contained
in this Agreement shall survive the execution and delivery of this Agreement and
the termination hereof.

      5.    DEFAULT, RIGHTS AND REMEDIES OF THE LENDER.

      5.1  Obligations.  If an Event of Default shall exist or occur, the Lender
may notify the  Borrower  of its  election  to  terminate  this  Agreement,  the
Obligations shall be accelerated and all of the Obligations shall automatically,
without further notice of any kind, be immediately due and payable.

      5.2 Rights and Remedies  Generally.  Upon acceleration of the Obligations,
the Lender shall have, in addition to any other rights and remedies contained in
this  Agreement,  all of the  rights  and  remedies  under  the  Code  or  other
applicable  laws,  all of which  rights and  remedies  shall be  cumulative  and
non-exclusive, to the extent permitted by law.

      6.    OTHER RIGHTS AND OBLIGATIONS.

      6.1 Waiver.  The  Lender's  failure,  at any time or times  hereafter,  to
require  strict  performance  by the Borrower of any provision of this Agreement
shall not waive, affect or diminish any right of the Lender thereafter to demand
strict compliance and performance therewith. Any


<PAGE>



suspension  or waiver by the Lender of a Default  or an Event of  Default  under
this Agreement shall not suspend,  waive or affect any other Default or Event of
Default under this  Agreement,  whether the same is prior or subsequent  thereto
and  whether  of the  same  or of a  different  kind or  character.  None of the
undertakings,  agreements,  warranties,  covenants  and  representations  of the
Borrower  contained in this  Agreement and no Default or Event of Default by the
Borrower under this  Agreement  shall be deemed to have been suspended or waived
by the Lender  unless such  suspension  or waiver is in writing and signed by an
officer of the Lender,  and directed to the Borrower  specifying such suspension
or waiver.  This  Agreement  may not be modified or amended  except in a written
agreement signed by the Borrower and the Lender.

      6.2 Reliance by the Lender. All covenants, agreements, representations and
warranties made herein by the Borrower shall,  notwithstanding any investigation
by the  Lender,  be deemed to be material to and to have been relied upon by the
Lender.

      6.3 Parties and Assignment.  Whenever in this Agreement  reference is made
to any of the  parties  hereto,  such  reference  shall be  deemed  to  include,
wherever  applicable,  a reference to the successors and assigns of the Borrower
and the Lender. Notwithstanding the foregoing, the Borrower may not sell, assign
or transfer this Agreement,  including  without  limitation its rights,  titles,
interests,  remedies, powers and/or duties hereunder or thereunder. The Borrower
hereby consents to the Lender's sale, assignment, transfer or other disposition,
at any time and from time to time hereafter, of this Agreement including without
limitation all or any part of the Lender's rights, titles, interests,  remedies,
powers and/or duties hereunder or thereunder.

      6.4 Applicable Law; Severability. THIS AGREEMENT SHALL BE CONSTRUED IN ALL
RESPECTS IN  ACCORDANCE  WITH,  AND  GOVERNED BY, ALL OF THE  PROVISIONS  OF THE
NEBRASKA  UNIFORM  COMMERCIAL CODE AND BY THE OTHER INTERNAL LAWS (AS OPPOSED TO
CONFLICTS OF LAW PROVISIONS) OF THE STATE OF NEBRASKA.  WHENEVER POSSIBLE,  EACH
PROVISION  OF THIS  AGREEMENT  SHALL BE  INTERPRETED  IN SUCH A MANNER  AS TO BE
EFFECTIVE AND VALID UNDER APPLICABLE LAW, BUT IF ANY PROVISION OF THIS AGREEMENT
SHALL BE PROHIBITED BY OR INVALID UNDER  APPLICABLE LAW, SUCH PROVISION SHALL BE
INEFFECTIVE  ONLY TO THE  EXTENT  OF SUCH  PROHIBITION  OR  INVALIDITY,  WITHOUT
INVALIDATING  THE REMAINDER OF SUCH  PROVISIONS  OR THE REMAINING  PROVISIONS OF
THIS AGREEMENT.

      6.5  Submission  to  Jurisdiction;  Waiver of Jury and Bond.  THE BORROWER
HEREBY CONSENTS TO THE JURISDICTION OF ANY STATE OR FEDERAL COURT LOCATED WITHIN
THE COUNTY OF DOUGLAS,  STATE OF NEBRASKA,  AND IRREVOCABLY AGREES THAT, SUBJECT
TO THE LENDER'S SOLE AND ABSOLUTE ELECTION,  ALL ACTIONS OR PROCEEDINGS RELATING
TO THIS AGREEMENT SHALL BE LITIGATED IN SUCH COURTS, AND THE BORROWER WAIVES ANY
OBJECTION  WHICH IT MAY HAVE BASED ON IMPROPER  VENUE OR FORUM NON CONVENIENS TO
THE CONDUCT OF ANY PROCEEDING IN ANY SUCH COURT AND WAIVES  PERSONAL  SERVICE OF
ANY AND ALL PROCESS  UPON IT, AND  CONSENTS  THAT ALL SUCH SERVICE OF PROCESS BE
MADE BY MAIL OR MESSENGER DIRECTED TO IT AT THE ADDRESS SET


<PAGE>



FORTH IN  SUBSECTION  6.9 BELOW AND THAT  SERVICE  SO MADE SHALL BE DEEMED TO BE
COMPLETED  UPON THE  EARLIER OF ACTUAL  RECEIPT OR THREE (3) DAYS AFTER THE SAME
SHALL HAVE BEEN POSTED TO THE BORROWER.  THE LENDER AND THE BORROWER ACKNOWLEDGE
THAT THE TIME AND EXPENSE REQUIRED FOR TRIAL BY JURY EXCEED THE TIME AND EXPENSE
REQUIRED  FOR A BENCH TRIAL AND HEREBY  WAIVE,  TO THE EXTENT  PERMITTED BY LAW,
TRIAL BY JURY,  AND WAIVE ANY BOND OR SURETY OR  SECURITY  UPON SUCH BOND  WHICH
MIGHT, BUT FOR THIS WAIVER, BE REQUIRED OF THE LENDER. NOTHING CONTAINED IN THIS
SUBSECTION  6.5 SHALL  AFFECT THE RIGHT OF THE LENDER TO SERVE LEGAL  PROCESS IN
ANY OTHER MANNER PERMITTED BY LAW OR AFFECT THE RIGHT OF THE LENDER TO BRING ANY
ACTION OR  PROCEEDING  AGAINST THE BORROWER OR ITS PROPERTY IN THE COURTS OF ANY
OTHER JURISDICTION.

      6.6  Marshalling.  The Lender shall be under no  obligation to marshal any
assets in favor of the  Borrower  or any other party or against or in payment of
any or all of the Obligations.

      6.7 Section Titles.  The section titles  contained in this Agreement shall
be without  substantive  meaning or content of any kind whatsoever and are not a
part of the agreement between the parties.

      6.8 Continuing  Effect.  This  Agreement  shall continue in full force and
effect  so long as any  Obligations  shall  be  owed  to the  Lender;  provided,
however, that the Borrower's  obligations to indemnify the Lender shall continue
notwithstanding any termination of this Agreement.

      6.9 Notices.  Except as otherwise  expressly  provided herein,  any notice
required  or desired  to be served,  given or  delivered  hereunder  shall be in
writing,  and shall be deemed to have been  validly  served,  given or delivered
three (3) days after  deposit in the United States  mails,  with proper  postage
prepaid, or upon delivery by courier or upon transmission by telex,  telecopy or
similar  electronic  medium to the  addresses  set forth in the preamble to this
Agreement or to such other address as each party  designates to the other in the
manner herein prescribed.

      6.10  Waivers  With  Respect to Other  Instruments.  The  Borrower  waives
presentment,  demand and protest  and notice of  presentment,  demand,  protest,
default, nonpayment,  maturity, release, compromise,  settlement,  extension, or
renewal of any or all commercial paper,  Accounts,  contract rights,  documents,
instruments,  chattel  paper and  guaranties  at any time held by the  Lender on
which the  Borrower  may in any way be liable and hereby  ratifies  and confirms
whatever the Lender may do regarding the enforcement, collection, compromise, or
release thereof.

      6.11 Entire  Agreement.  This Agreement,  including all exhibits and other
documents  attached hereto or incorporated by reference herein,  constitutes the
entire  agreement of the parties with respect to the subject  matter  hereof and
supersedes  all other  understandings,  oral or  written,  with  respect  to the
subject matter hereof.

6.12  Equitable Relief.  The Borrower recognizes that, in the event the Borrower
fails to perform, observe or discharge any of its Obligations under this
Agreement, any remedy at law may


<PAGE>



prove to be inadequate relief to the Lender; therefore, the Borrower agrees that
the  Lender,  if the Lender so  requests,  shall be entitled  to  temporary  and
permanent  injunctive  relief in any such case without the  necessity of proving
actual damages.

      6.13 No  Fiduciary  Relationship.  No  provision  herein  and no course of
dealing between the parties shall be deemed to create any fiduciary relationship
between the Lender and the Borrower.

      IN WITNESS  WHEREOF,  this  Agreement has been duly executed as of the day
and year first above written.



LENDER:                                  BORROWER:
MARY M. COLLISON                         ADVANCED BUSINESS SCIENCES, INC.



- ------------------------                By:------------------------------





<PAGE>



                                  Exhibit "A"


<PAGE>



                                PROMISSORY NOTE

$500,000                                                        April 30, 1999


      FOR VALUE RECEIVED, the undersigned,  ADVANCED BUSINESS SCIENCES,  INC., a
Delaware corporation (the "Borrower"), hereby unconditionally promises to pay to
the  order of Mary M.  Collison  (the  "Lender"),  at 640  Hidden  Valley  Road,
Carroll,  Iowa  51401-3205,  or at  such  other  place  as the  holder  of  this
promissory  note (this  "Note") may from time to time  designate in writing,  in
lawful money of the United States of America and in immediately available funds,
the principal sum of Five Hundred Thousand  Dollars  ($500,000) or, if less, the
aggregate  unpaid  principal  amount of all advances made pursuant to subsection
2.1 of the  Loan  Agreement  (as  hereinafter  defined)  at  such  times  as are
specified in and in accordance with the provisions of the Loan  Agreement.  This
Note is referred to in and was executed and  delivered  pursuant to that certain
Loan  Agreement of even date  herewith  between the Borrower and the Lender (the
"Loan  Agreement"),  to which  reference  is hereby made for a statement  of the
terms and conditions under which the loans evidenced hereby were made and are to
be repaid and for a statement of the Lender's remedies upon the occurrence of an
Event of Default(as  defined therein).  All terms which are capitalized and used
herein  (which are not  otherwise  specifically  defined  herein)  and which are
defined in the Loan Agreement  shall be used in this Note as defined in the Loan
Agreement.

      The Borrower  further  promises to pay interest on the outstanding  unpaid
principal amount hereof, as provided in the Loan Agreement, from the date hereof
until  payment in full hereof at the Regular Rate as  determined  in  accordance
with the Loan Agreement; provided, however, that five (5) days following written
notice by the Lender to the  Borrower  that an Event of Default has occurred and
is continuing, the Borrower promises to pay the Lender interest from the date of
such Event of Default to and including the date of cure of such Event of Default
on the unpaid  principal  amount  hereof at the Default  Rate as  determined  in
accordance with the Loan Agreement. Interest shall be payable monthly in arrears
on the first day of each calendar  month in accordance  with the Loan  Agreement
and shall be  computed on the basis of a 360-day  year for the actual  number of
days elapsed.

      If a payment  hereunder  becomes due and payable  other than on a Business
Day, the due date thereof shall be extended to the next succeeding  Business Day
and interest  shall be payable  thereon  during such extension at the applicable
rate specified above. Checks, drafts or similar items of payment received by the
Lender shall not constitute  payment,  but credit therefor shall, solely for the
purpose of computing  interest earned by the Lender, be given in accordance with
the Loan Agreement.

      The Lender shall have the exclusive  right to apply and to reapply any and
all payments  hereunder  against the  Obligations in the manner set forth in the
Loan Agreement.

      The Borrower hereby waives demand, presentment, protest, notice of demand,
presentment, protest and nonpayment.



<PAGE>



      THIS NOTE  SHALL BE  INTERPRETED  AND THE RIGHTS  AND  LIABILITIES  OF THE
PARTIES  HERETO  DETERMINED IN ACCORDANCE  WITH THE INTERNAL LAWS (AS OPPOSED TO
CONFLICTS OF LAW  PROVISIONS)  AND DECISIONS OF THE STATE OF NEBRASKA.  WHENEVER
POSSIBLE EACH  PROVISION OF THIS NOTE SHALL BE  INTERPRETED IN SUCH MANNER AS TO
BE EFFECTIVE AND VALID UNDER  APPLICABLE  LAW, BUT IF ANY PROVISION OF THIS NOTE
SHALL BE PROHIBITED BY OR INVALID UNDER  APPLICABLE LAW, SUCH PROVISION SHALL BE
INEFFECTIVE  TO  THE  EXTENT  OF  SUCH   PROHIBITION   OR  INVALIDITY,   WITHOUT
INVALIDATING THE REMAINDER OF SUCH PROVISION OR THE REMAINING PROVISIONS OF THIS
NOTE.  WHENEVER IN THIS NOTE  REFERENCE  IS MADE TO THE LENDER OR THE  BORROWER,
SUCH REFERENCE SHALL BE DEEMED TO INCLUDE,  AS APPLICABLE,  A REFERENCE TO THEIR
RESPECTIVE  SUCCESSORS AND ASSIGNS. THE PROVISIONS OF THIS NOTE SHALL BE BINDING
UPON  AND  SHALL  INURE TO THE  BENEFIT  OF SUCH  SUCCESSORS  AND  ASSIGNS.  THE
BORROWER'S SUCCESSORS AND ASSIGNS SHALL INCLUDE, WITHOUT LIMITATION, A RECEIVER,
TRUSTEE OR DEBTOR IN POSSESSION OF OR FOR THE BORROWER.




                                         ADVANCED BUSINESS SCIENCES, INC.



                                         By:-----------------------------------






                                LOAN AGREEMENT


      This  Loan  Agreement  (this  "Agreement"),  dated as of this  30th day of
April,  1999,  by and  between  Advanced  Business  Sciences,  Inc.,  a Delaware
corporation,, with its principal place of business and chief executive office at
3345 No. 107th Street,  Omaha,  Nebraska  68134 (the  "Borrower"),  and James L.
Pietig residing at 129 East Pleasant Ridge Drive, Carroll, Iowa 51401- 3211 (the
"Lender").

      WHEREAS, in order to provide funds to the Borrower for working capital and
other  purposes,  the  Borrower  desires to borrow up to Five  Hundred  Thousand
Dollars  ($500,000) from the Lender, and the Lender is willing to make a loan to
the Borrower of such amount, upon the terms and conditions set forth herein;

      NOW THEREFORE,  in  consideration  of the terms and  conditions  contained
herein,  and of any loans or extensions of credit  heretofore,  now or hereafter
made to or for the benefit of the  Borrower by the  Lender,  the parties  hereto
hereby agree as follows:

      1.    DEFINITIONS.

      1.1   General Terms.  When used herein, the following terms shall have the
following meanings:

      "Affiliate" shall mean any Person (a) that directly or indirectly, through
one or more  intermediaries,  controls or is  controlled  by, or is under common
control with a Person, including, without limitation, the officers and directors
of such Person,  (b) that directly or beneficially  owns or holds 20% or more of
any equity interest in such Person,  excluding the Lender, or (c) 20% or more of
whose voting stock (or in the case of a Person which is not a  corporation,  20%
or more of any equity interest) is owned directly or beneficially or held by the
Affiliate. As used herein, the term "control" shall mean possession, directly or
indirectly,  of the power to direct  the  management  or  policies  of a Person,
whether through ownership of securities or otherwise.

      "Assets"  shall mean  assets  reflected  on a balance  sheet  prepared  in
accordance  with  Generally   Accepted   Accounting   Principles,   except  that
investments in or monies due from any Affiliate shall be excluded therefrom.

      "Business  Day" shall mean any day other than a Saturday,  Sunday or other
day on which banks in Omaha, Nebraska, are authorized or required to be closed.

      "Default"  shall mean an event  which  through  the passage of time or the
service of notice or both would mature into an Event of Default.

      "Default  Rate"  shall  mean a rate of  interest  per  annum  equal to the
Regular Rate plus five percent.



<PAGE>



      "Event of Default"  shall mean the  occurrence  or existence of any one or
more  of the  following  events:  (a)  the  Borrower  fails  to  pay  any of its
"Obligations"  hereunder  upon  demand or when such  Obligations  are due or are
declared due; (b) the Borrower fails or neglects to perform, keep or observe any
of the covenants,  conditions or agreements  contained in any of the subsections
of this Agreement or in any of the other ; or (c) any warranty or representation
now or  hereafter  made by the  Borrower in  connection  with this  Agreement is
untrue or incorrect  in any  material  respect,  or any  schedule,  certificate,
statement,  report,  financial data, notice, or writing furnished at any time by
the Borrower to the Lender is untrue or incorrect in any material respect, as of
the date on which the  warranty,  representation  or the facts set forth therein
are stated, certified or deemed made.

      "Generally Accepted  Accounting  Principles" shall mean, as of the date of
any determination with respect thereto, generally accepted accounting principles
as  used  by the  Financial  Accounting  Standards  Board  and/or  the  American
Institute of Certified Public Accountants,  consistently  applied and maintained
throughout the periods indicated.

      "Indebtedness"  shall mean at a  particular  time,  (a)  indebtedness  for
borrowed  money or for the  deferred  purchase  price of property or services in
respect of which the Borrower is liable,  contingently or otherwise,  as obligor
or otherwise or any commitment by which the Borrower  assures a creditor against
loss, including contingent reimbursement  obligations with respect to letters of
credit,  (b)  indebtedness  guaranteed in any manner by the Borrower,  including
guaranties  in  the  form  of an  agreement  to  repurchase  or  reimburse,  (c)
obligations  under leases which shall have been or should be, in accordance with
Generally Accepted Accounting Principles,  recorded as capital leases in respect
of which  obligations  the Borrower is liable,  contingently  or  otherwise,  as
obligor, guarantor or otherwise, or in respect of which obligations the Borrower
assures a creditor against loss, and (d) any unfunded obligation of the Borrower
to a "multiemployer  plan" as such term is defined under the Employee Retirement
Income Security Act of 1974, as amended ("ERISA").

      "Liabilities" shall have the meaning usually given that term in accordance
with Generally Accepted Accounting Principles, and shall include Indebtedness.

      "Line of Credit" shall have the meaning ascribed thereto at subsection 2.1
hereof.

      "Note"   shall  mean  a   promissory   note  issued  by  the  Borrower  in
substantially the form of Exhibit "A" hereto.

      "Obligations"  shall mean all of the Borrower's  obligations,  liabilities
and  indebtedness to the Lender and/or to any Affiliate of the Lender of any and
every kind and nature arising or existing under this  Agreement,  whether now or
hereafter  owing,  arising,  due or payable and  howsoever  evidenced,  created,
incurred,  acquired,  or owing, whether primary,  secondary,  direct,  indirect,
contingent, fixed or otherwise (including obligations of performance).

      "Person"  shall mean any  individual,  sole  proprietorship,  partnership,
joint venture, trust,  unincorporated  organization,  association,  corporation,
institution,  entity,  party, or government (whether national,  federal,  state,
provincial, county, city, municipal or otherwise, including, without limitation,
any instrumentality, division, agency, body or department thereof).


<PAGE>




      "Plan" shall mean any employee  benefit or other plan  maintained  for the
employees of the  Borrower or to which the  Borrower is obligated to  contribute
and subject to Title IV of ERISA.

      "Regular  Rate" shall mean a rate of interest per annum equal to the prime
rate of interest from time to time  established by First Star Bank of Iowa, N.A.
plus 25 basis points.

      1.2 Accounting  Terms.  Any accounting  terms used in this Agreement which
are not specifically  defined herein shall have the meanings  customarily  given
them in accordance with Generally Accepted Accounting Principles.

      1.3 Other Terms Defined in Nebraska  Uniform  Commercial  Code.  All other
terms  contained in this  Agreement  (and which are not  otherwise  specifically
defined herein) shall have the meanings provided in the Uniform  Commercial Code
of the State of Nebraska (the "Code") to the extent the same are used or defined
therein.

      1.4 Effective Date. All references to "the date hereof," "the date of this
Agreement,"  "the effective  date hereof,"  "effective as of the date hereof" or
"of even date  herewith"  contained  herein  or in the other  shall be deemed to
refer to the day and year first above written.

      2.    CREDIT.

      2.1 Line of Credit.  Subject to the terms and conditions herein set forth,
Lender  agrees to advance  funds to Borrower  upon its request from time to time
beginning  on the date  hereof and  terminating  on January  31,  2000,  in such
amounts as the Borrower may from time to time request, in increments of not less
than Ten  Thousand  Dollars  ($10,000),  up to but not  exceeding  Five  Hundred
Thousand  Dollars  ($500,000)  at any time  outstanding  (the "Line of Credit").
Borrower  may reborrow any advance once such advance has been repaid in whole or
in part.

      2.2   Interest.

      (a) So long as no Event of Default has  occurred  and is  continuing,  the
Borrower shall pay to the Lender interest on the outstanding  principal  balance
of the Obligations at the Regular Rate.

      (b) Upon  delivery of written  notice by the Lender to the Borrower of the
occurrence of an Event of Default, the Borrower shall pay to the Lender interest
from the date of such Event of Default to and including the date of cure of such
Event of Default on the outstanding  principal balance of the Obligations at the
Default Rate applicable to such Obligations.

      2.3 Method of Making Payments.  All payments to be made by the Borrower to
the Lender  hereunder shall be made to the Lender at its address set forth above
not later than 12:00 noon Omaha time on the date when due in lawful money of the
United States of America and immediately available funds.

      2.4 Term of this Agreement. This Agreement shall be effective until all of
the obligations  under this Agreement have been finally paid in full;  provided,
that even after full and final payment


<PAGE>



of all Obligations hereunder,  the Borrower's Obligation to indemnify the Lender
in accordance with the terms hereof shall continue.

      2.5 Payment Dates and Basis of  Calculation.  Any payment due hereunder on
any day other than a Business Day shall be due on the next  succeeding  Business
Day, and if such payment shall bear interest in  accordance  herewith,  interest
shall  accrue to the date of  payment.  All  interest  and fees  (other than the
prepayment  fee) shall be computed (on a daily basis) on the basis of a 360- day
year for the actual number of days elapsed.

      2.6 Additional  Consideration.  As additional  consideration  for entering
into this  Agreement,  the Borrower shall issue to the Lender 83,333 fully paid,
nonassessable  shares of  Borrower's  common  stock,  together with a warrant to
purchase  83,333  shares of such common stock at an exercise  price of $1.00 per
share, exercisable at any time on or before October 31, 2000.

      3.    CONDITIONS TO FUNDING OF LINE OF CREDIT.

      The advance of funds under the Line of Credit  shall be  conditioned  upon
the matters set forth  below,  the  delivery of the  following  documents to the
Lender,  in form and substance  satisfactory to the Lender,  and consummation of
all of the  transactions or the  satisfaction of each condition  contemplated by
each such document.

      3.1   Warranties   and   Representations.   All  of  the   warranties  and
representations  of the Borrower  contained  herein shall be true and correct in
all material respects on and as of the date hereof.

      3.2 No Default.  As  determined  by the  Lender,  neither a Default nor an
Event of Default  shall have occurred and be continuing or will result from such
advance.

      3.3 No  Litigation.  There shall be (i) no  litigation,  investigation  or
proceeding pending or threatened against the Borrower or any officer,  director,
or  executive  (as  applicable)  of the  Borrower  (A) in  connection  with this
Agreement  which,  in the sole opinion of the Lender,  is deemed material or (B)
which, if adversely determined, would, in the sole opinion of the Lender, have a
material  adverse  effect on the financial  condition,  business,  or results of
operations of the Borrower;  and (ii) no injunction,  writ, restraining order or
other  order  of any  nature  materially  adverse  to  the  Borrower  issued  or
threatened by any court or governmental agency.

      4.  WARRANTIES.

      The Borrower  represents  and warrants and covenants and agrees that as of
the date of the  execution  of this  Agreement,  and  continuing  so long as any
Obligations  remain  outstanding,  and  (even if there  shall be no  Obligations
outstanding) so long as this Agreement remains in effect:

      4.1  Existence.  The Borrower is a  corporation  duly  organized,  validly
existing  and in good  standing  in the  State  of  Delaware.  The  Borrower  is
qualified to transact business as a foreign


<PAGE>



corporation  in, and is in good standing  under the laws of, all states in which
the Borrower is required by applicable  law to maintain such  qualification  and
good standing.

      4.2 Authority.  The Borrower has full power,  authority and legal right to
enter into this  Agreement.  The  execution and delivery by the Borrower of this
Agreement:  (i) have been duly authorized by all necessary action on the part of
the Borrower  (including  any  required  stockholders  action);  (ii) are not in
contravention of the terms of the Borrower's Articles of Incorporation or Bylaws
or of any  indenture,  agreement or undertaking to which the Borrower is a party
or by which the Borrower or any of its property is bound;  (iii) do not and will
not require any governmental consent,  registration or approval; (iv) do not and
will not contravene any  contractual  or  governmental  restriction to which the
Borrower or any of its  property  may be  subject;  and (v) do not and will not,
except as  contemplated  herein,  result in the imposition of any lien,  charge,
security  interest or  encumbrance  upon any property of the Borrower  under any
existing indenture,  mortgage,  deed of trust, loan or credit agreement or other
material  agreement or  instrument  to which the Borrower is a party or by which
the Borrower or any of its  property may be bound or affected.  The Borrower has
the full  corporate  authority  to own or lease and operate its  property and to
conduct the business in which it is  currently  engaged and in which it proposes
to engage.

      4.3 Binding Effect. This Agreement has been duly executed and delivered or
filed,  as  applicable,  by  the  Borrower,  is the  legal,  valid  and  binding
obligations  of  the  Borrower  and  is  enforceable  against  the  Borrower  in
accordance with their terms.

      4.4 Place of Business.  As of the execution hereof, the principal place of
business  and chief  executive  office of the  Borrower  is at 3345 North  107th
Street, Omaha, Nebraska 68134

      4.5 Survival of Warranties.  All representations and warranties  contained
in this Agreement shall survive the execution and delivery of this Agreement and
the termination hereof.

      5.    DEFAULT, RIGHTS AND REMEDIES OF THE LENDER.

      5.1  Obligations.  If an Event of Default shall exist or occur, the Lender
may notify the  Borrower  of its  election  to  terminate  this  Agreement,  the
Obligations shall be accelerated and all of the Obligations shall automatically,
without further notice of any kind, be immediately due and payable.

      5.2 Rights and Remedies  Generally.  Upon acceleration of the Obligations,
the Lender shall have, in addition to any other rights and remedies contained in
this  Agreement,  all of the  rights  and  remedies  under  the  Code  or  other
applicable  laws,  all of which  rights and  remedies  shall be  cumulative  and
non-exclusive, to the extent permitted by law.

      6.    OTHER RIGHTS AND OBLIGATIONS.

      6.1 Waiver.  The  Lender's  failure,  at any time or times  hereafter,  to
require  strict  performance  by the Borrower of any provision of this Agreement
shall not waive, affect or diminish any right of the Lender thereafter to demand
strict compliance and performance therewith. Any


<PAGE>



suspension  or waiver by the Lender of a Default  or an Event of  Default  under
this Agreement shall not suspend,  waive or affect any other Default or Event of
Default under this  Agreement,  whether the same is prior or subsequent  thereto
and  whether  of the  same  or of a  different  kind or  character.  None of the
undertakings,  agreements,  warranties,  covenants  and  representations  of the
Borrower  contained in this  Agreement and no Default or Event of Default by the
Borrower under this  Agreement  shall be deemed to have been suspended or waived
by the Lender  unless such  suspension  or waiver is in writing and signed by an
officer of the Lender,  and directed to the Borrower  specifying such suspension
or waiver.  This  Agreement  may not be modified or amended  except in a written
agreement signed by the Borrower and the Lender.

      6.2 Reliance by the Lender. All covenants, agreements, representations and
warranties made herein by the Borrower shall,  notwithstanding any investigation
by the  Lender,  be deemed to be material to and to have been relied upon by the
Lender.

      6.3 Parties and Assignment.  Whenever in this Agreement  reference is made
to any of the  parties  hereto,  such  reference  shall be  deemed  to  include,
wherever  applicable,  a reference to the successors and assigns of the Borrower
and the Lender. Notwithstanding the foregoing, the Borrower may not sell, assign
or transfer this Agreement,  including  without  limitation its rights,  titles,
interests,  remedies, powers and/or duties hereunder or thereunder. The Borrower
hereby consents to the Lender's sale, assignment, transfer or other disposition,
at any time and from time to time hereafter, of this Agreement including without
limitation all or any part of the Lender's rights, titles, interests,  remedies,
powers and/or duties hereunder or thereunder.

      6.4 Applicable Law; Severability. THIS AGREEMENT SHALL BE CONSTRUED IN ALL
RESPECTS IN  ACCORDANCE  WITH,  AND  GOVERNED BY, ALL OF THE  PROVISIONS  OF THE
NEBRASKA  UNIFORM  COMMERCIAL CODE AND BY THE OTHER INTERNAL LAWS (AS OPPOSED TO
CONFLICTS OF LAW PROVISIONS) OF THE STATE OF NEBRASKA.  WHENEVER POSSIBLE,  EACH
PROVISION  OF THIS  AGREEMENT  SHALL BE  INTERPRETED  IN SUCH A MANNER  AS TO BE
EFFECTIVE AND VALID UNDER APPLICABLE LAW, BUT IF ANY PROVISION OF THIS AGREEMENT
SHALL BE PROHIBITED BY OR INVALID UNDER  APPLICABLE LAW, SUCH PROVISION SHALL BE
INEFFECTIVE  ONLY TO THE  EXTENT  OF SUCH  PROHIBITION  OR  INVALIDITY,  WITHOUT
INVALIDATING  THE REMAINDER OF SUCH  PROVISIONS  OR THE REMAINING  PROVISIONS OF
THIS AGREEMENT.

      6.5  Submission  to  Jurisdiction;  Waiver of Jury and Bond.  THE BORROWER
HEREBY CONSENTS TO THE JURISDICTION OF ANY STATE OR FEDERAL COURT LOCATED WITHIN
THE COUNTY OF DOUGLAS,  STATE OF NEBRASKA,  AND IRREVOCABLY AGREES THAT, SUBJECT
TO THE LENDER'S SOLE AND ABSOLUTE ELECTION,  ALL ACTIONS OR PROCEEDINGS RELATING
TO THIS AGREEMENT SHALL BE LITIGATED IN SUCH COURTS, AND THE BORROWER WAIVES ANY
OBJECTION  WHICH IT MAY HAVE BASED ON IMPROPER  VENUE OR FORUM NON CONVENIENS TO
THE CONDUCT OF ANY PROCEEDING IN ANY SUCH COURT AND WAIVES  PERSONAL  SERVICE OF
ANY AND ALL PROCESS  UPON IT, AND  CONSENTS  THAT ALL SUCH SERVICE OF PROCESS BE
MADE BY MAIL OR MESSENGER DIRECTED TO IT AT THE ADDRESS SET


<PAGE>



FORTH IN  SUBSECTION  6.9 BELOW AND THAT  SERVICE  SO MADE SHALL BE DEEMED TO BE
COMPLETED  UPON THE  EARLIER OF ACTUAL  RECEIPT OR THREE (3) DAYS AFTER THE SAME
SHALL HAVE BEEN POSTED TO THE BORROWER.  THE LENDER AND THE BORROWER ACKNOWLEDGE
THAT THE TIME AND EXPENSE REQUIRED FOR TRIAL BY JURY EXCEED THE TIME AND EXPENSE
REQUIRED  FOR A BENCH TRIAL AND HEREBY  WAIVE,  TO THE EXTENT  PERMITTED BY LAW,
TRIAL BY JURY,  AND WAIVE ANY BOND OR SURETY OR  SECURITY  UPON SUCH BOND  WHICH
MIGHT, BUT FOR THIS WAIVER, BE REQUIRED OF THE LENDER. NOTHING CONTAINED IN THIS
SUBSECTION  6.5 SHALL  AFFECT THE RIGHT OF THE LENDER TO SERVE LEGAL  PROCESS IN
ANY OTHER MANNER PERMITTED BY LAW OR AFFECT THE RIGHT OF THE LENDER TO BRING ANY
ACTION OR  PROCEEDING  AGAINST THE BORROWER OR ITS PROPERTY IN THE COURTS OF ANY
OTHER JURISDICTION.

      6.6  Marshalling.  The Lender shall be under no  obligation to marshal any
assets in favor of the  Borrower  or any other party or against or in payment of
any or all of the Obligations.

      6.7 Section Titles.  The section titles  contained in this Agreement shall
be without  substantive  meaning or content of any kind whatsoever and are not a
part of the agreement between the parties.

      6.8 Continuing  Effect.  This  Agreement  shall continue in full force and
effect  so long as any  Obligations  shall  be  owed  to the  Lender;  provided,
however, that the Borrower's  obligations to indemnify the Lender shall continue
notwithstanding any termination of this Agreement.

      6.9 Notices.  Except as otherwise  expressly  provided herein,  any notice
required  or desired  to be served,  given or  delivered  hereunder  shall be in
writing,  and shall be deemed to have been  validly  served,  given or delivered
three (3) days after  deposit in the United States  mails,  with proper  postage
prepaid, or upon delivery by courier or upon transmission by telex,  telecopy or
similar  electronic  medium to the  addresses  set forth in the preamble to this
Agreement or to such other address as each party  designates to the other in the
manner herein prescribed.

      6.10  Waivers  With  Respect to Other  Instruments.  The  Borrower  waives
presentment,  demand and protest  and notice of  presentment,  demand,  protest,
default, nonpayment,  maturity, release, compromise,  settlement,  extension, or
renewal of any or all commercial paper,  Accounts,  contract rights,  documents,
instruments,  chattel  paper and  guaranties  at any time held by the  Lender on
which the  Borrower  may in any way be liable and hereby  ratifies  and confirms
whatever the Lender may do regarding the enforcement, collection, compromise, or
release thereof.

      6.11 Entire  Agreement.  This Agreement,  including all exhibits and other
documents  attached hereto or incorporated by reference herein,  constitutes the
entire  agreement of the parties with respect to the subject  matter  hereof and
supersedes  all other  understandings,  oral or  written,  with  respect  to the
subject matter hereof.

      6.12  Equitable Relief.  The Borrower recognizes that, in the event the
Borrower fails to perform, observe or discharge any of its Obligations under
this Agreement, any remedy at law may


<PAGE>



prove to be inadequate relief to the Lender; therefore, the Borrower agrees that
the  Lender,  if the Lender so  requests,  shall be entitled  to  temporary  and
permanent  injunctive  relief in any such case without the  necessity of proving
actual damages.

      6.13 No  Fiduciary  Relationship.  No  provision  herein  and no course of
dealing between the parties shall be deemed to create any fiduciary relationship
between the Lender and the Borrower.

      IN WITNESS  WHEREOF,  this  Agreement has been duly executed as of the day
and year first above written.



LENDER:                                  BORROWER:
JAMES L. PIETIG                          ADVANCED BUSINESS SCIENCES, INC.



                                         By:
- -----------------------                     -----------------------------------





<PAGE>



                                  Exhibit "A"



<PAGE>



                                PROMISSORY NOTE

$500,000                                                        April 30, 1999


      FOR VALUE RECEIVED, the undersigned,  ADVANCED BUSINESS SCIENCES,  INC., a
Delaware corporation (the "Borrower"), hereby unconditionally promises to pay to
the order of James L. Pietig (the  "Lender"),  at 129 East Pleasant Ridge Drive,
Carroll,  Iowa  51401-3211,  or at  such  other  place  as the  holder  of  this
promissory  note (this  "Note") may from time to time  designate in writing,  in
lawful money of the United States of America and in immediately available funds,
the principal sum of Five Hundred Thousand  Dollars  ($500,000) or, if less, the
aggregate  unpaid  principal  amount of all advances made pursuant to subsection
2.1 of the  Loan  Agreement  (as  hereinafter  defined)  at  such  times  as are
specified in and in accordance with the provisions of the Loan  Agreement.  This
Note is referred to in and was executed and  delivered  pursuant to that certain
Loan  Agreement of even date  herewith  between the Borrower and the Lender (the
"Loan  Agreement"),  to which  reference  is hereby made for a statement  of the
terms and conditions under which the loans evidenced hereby were made and are to
be repaid and for a statement of the Lender's remedies upon the occurrence of an
Event of Default(as  defined therein).  All terms which are capitalized and used
herein  (which are not  otherwise  specifically  defined  herein)  and which are
defined in the Loan Agreement  shall be used in this Note as defined in the Loan
Agreement.

      The Borrower  further  promises to pay interest on the outstanding  unpaid
principal amount hereof, as provided in the Loan Agreement, from the date hereof
until  payment in full hereof at the Regular Rate as  determined  in  accordance
with the Loan Agreement; provided, however, that five (5) days following written
notice by the Lender to the  Borrower  that an Event of Default has occurred and
is continuing, the Borrower promises to pay the Lender interest from the date of
such Event of Default to and including the date of cure of such Event of Default
on the unpaid  principal  amount  hereof at the Default  Rate as  determined  in
accordance with the Loan Agreement. Interest shall be payable monthly in arrears
on the first day of each calendar  month in accordance  with the Loan  Agreement
and shall be  computed on the basis of a 360-day  year for the actual  number of
days elapsed.

      If a payment  hereunder  becomes due and payable  other than on a Business
Day, the due date thereof shall be extended to the next succeeding  Business Day
and interest  shall be payable  thereon  during such extension at the applicable
rate specified above. Checks, drafts or similar items of payment received by the
Lender shall not constitute  payment,  but credit therefor shall, solely for the
purpose of computing  interest earned by the Lender, be given in accordance with
the Loan Agreement.

      The Lender shall have the exclusive  right to apply and to reapply any and
all payments  hereunder  against the  Obligations in the manner set forth in the
Loan Agreement.

      The Borrower hereby waives demand, presentment, protest, notice of demand,
presentment, protest and nonpayment.



<PAGE>



      THIS NOTE  SHALL BE  INTERPRETED  AND THE RIGHTS  AND  LIABILITIES  OF THE
PARTIES  HERETO  DETERMINED IN ACCORDANCE  WITH THE INTERNAL LAWS (AS OPPOSED TO
CONFLICTS OF LAW  PROVISIONS)  AND DECISIONS OF THE STATE OF NEBRASKA.  WHENEVER
POSSIBLE EACH  PROVISION OF THIS NOTE SHALL BE  INTERPRETED IN SUCH MANNER AS TO
BE EFFECTIVE AND VALID UNDER  APPLICABLE  LAW, BUT IF ANY PROVISION OF THIS NOTE
SHALL BE PROHIBITED BY OR INVALID UNDER  APPLICABLE LAW, SUCH PROVISION SHALL BE
INEFFECTIVE  TO  THE  EXTENT  OF  SUCH   PROHIBITION   OR  INVALIDITY,   WITHOUT
INVALIDATING THE REMAINDER OF SUCH PROVISION OR THE REMAINING PROVISIONS OF THIS
NOTE.  WHENEVER IN THIS NOTE  REFERENCE  IS MADE TO THE LENDER OR THE  BORROWER,
SUCH REFERENCE SHALL BE DEEMED TO INCLUDE,  AS APPLICABLE,  A REFERENCE TO THEIR
RESPECTIVE  SUCCESSORS AND ASSIGNS. THE PROVISIONS OF THIS NOTE SHALL BE BINDING
UPON  AND  SHALL  INURE TO THE  BENEFIT  OF SUCH  SUCCESSORS  AND  ASSIGNS.  THE
BORROWER'S SUCCESSORS AND ASSIGNS SHALL INCLUDE, WITHOUT LIMITATION, A RECEIVER,
TRUSTEE OR DEBTOR IN POSSESSION OF OR FOR THE BORROWER.




                                         ADVANCED BUSINESS SCIENCES, INC.



                                         By:-----------------------------------





                      BINARY SOFTWARE LICENSE AGREEMENT

THIS BINARY SOFTWARE LICENSE AGREEMENT ("Agreement") is made and entered into as
of the Effective Date, by and between SiRF TECHNOLOGY INCORPORATED, a California
corporation,  having offices at 39-10 Freedom  Circle,  Santa Clara,  California
95054  ("SiRF") and the entity  identified on the Licensee  signature line below
("Licensee").

RECITALS:

A. SiRF has developed and distributes the SiRFstarTM which is a technology for
use in the Global Position System ("GPS") market, which technology includes
Software Products and Documentation (as defined below) which SiRF owns, or has
rights to; and

B.  Licensee is  purchasing  SiRF Chips to  develop,  have  developed  or use in
connection with GPS Products, as defined below; and

C. As part of that  purchase,  SiRF  desires to grant to Licensee  and  Licensee
desires to obtain from SiRF a nonexclusive  license to use and sell the Software
Products and Documentation on the terms and conditions of this Agreement:

NOW, THEREFORE, the parties to this Agreement agree as follows:

1.                                               Definitions.

1,1 "Software  Products" shall mean the software identified in Exhibit A of this
Agreement and licensed to Licensee under

,this  Agreement,  together  with any Error  Corrections  that SiRF  supplies to
Licensee pursuant to this Agreement.

1.2  "Binary  Format"  shall mean the object code  version of  software  program
instructions.

1.3 "Documentation" shall mean all manuals, user documentation and other related
materials pertaining to the Software Products that SiRF provides to Licensee for
use in connection with the Software Products.

1.4  "Error  Corrections"  shall  mean  all bug  fixes,  including  patches  and
work-arounds, to the Software Products.

1.5  "Modifications"  shall mean all modifications and additions to the Software
Products other than Error Corrections.

I




<PAGE>







1.6 "SiRF  Chips"  shall mean  integrated  circuit  products  that SiRF sells to
Licensee during the term of this Agreement.

1.7 "Effective Date" shall mean the date set forth on the signature page of this
Agreement.

1.8 "GPS  Product"  shall  mean each  product  for sale and use in the market in
which the SiRF Chips purchased by Licensee are included.

2.
           Grant of Rights to Binary Software Products

SiRF hereby  grants to Licensee,  and Licensee  hereby  accepts,  subject to the
terms  and  conditions  of this  Agreement:  a  non-exclusive,  non-transferable
license to distribute and use the Binary Format  Software  Products (the "Binary
Software Products") and the related  Documentation,  solely with SiRF Chips as a
part of GPS Products;  and a  non-exclusive,  non-transferable  license to grant
sublicenses to others to do the foregoing.

Licensee  shall have no right or license to reproduce,  modify,  manufacture  or
otherwise use the Binary Software  Products except as expressly  provided above.
Further,  notwithstanding  Licensees  right to  sublicense  the Binary  Software
Products  to others  for  distribution  and use with SiRF Chips as a part of GPS
Products,  Licensee  shall have no right to sublicense  or authorize  parties to
reproduce,  modify,  manufacture or otherwise use the Binary  Software  Product,
without  SiRF's  prior  written  permission.  Licensee  agrees not to attempt to
modify, reverse engineer,  disassemble,  decompile or trace the execution of the
Binary Software Products, or of any portion thereof.

Licensee  shall have no right or  license to receive or use source  code for the
Software Products, unless such right or license is granted as part of a separate
written agreement between SiRF and Licensee.

3.
          Error Corrections and Modifications.

3.1 Error  Corrections  and Updates.  SiRF will have no  obligation  to make any
Error  Corrections  to the  Software  Products.  If SiRF  does  make  any  Error
Corrections,  then it may, at its  discretion,  elect to provide  Licensee  with
Error Corrections.

3.2   Modifications  by  SiRF.  SiRF  shall  be  under  no  obligation  to  make
Modifications  that may be required for  Licensee-specific  hardware,  firmware,
software,  or other requirements.  All Modifications to the Software Products or
Documentation  made by SiRF or its suppliers  shall be the sole property of SiRF
or of its suppliers, or both.

4.
          GPS Products.



<PAGE>



4.1  Title to  Software  Products  Incorporated  in GPS  Products.  Title to and
ownership  of any  portion  of the  Software  Products  incorporated  into a GPS
Product  shall at all times  remain  with SiRF or its  suppliers,  or both,  and
Licensee shall not have any title or ownership interest therein.

4.2  Title to GPS  Products.  Title to and  ownership  of any  portion  of a GPS
Product  created by Licensee  and not owned by SiRF or its  suppliers,  or both,
pursuant to Section 4.1 above, shall be held by-Licensee.

4.3  Maintenance  of GPS  Products.  SiRF shall not be  required  to maintain or
otherwise repair any GPS Product.  Any assistance in repairing errors or defects
in the GPS Products which may be provided by SiRF, in its sole discretion, shall
be subject to the terms of a separate agreement under which


[GRAPHIC OMITTED]



<PAGE>



Licensee shall pay SiRF in accordance with SiRF's then-current  charges for such
services.

4.4 Products  Developed by SiRF.  Nothing  contained in this Agreement  shall be
construed to limit SiRF's  rights to modify the Software  Products or to develop
other Products which are similar to or offer the same or similar improvements as
GPS Products developed by Licensee.

5.
          Protection of Software Products.

5.1 Ownership. Licensee acknowledges that all copies of the Software Products in
any form  provided by SiRF or made by Licensee are the sole  property of SiRF or
its suppliers,  or both. Licensee shall not have any right, title or interest in
or to any Software  Products,  or copies thereof except as expressly provided in
this Agreement,  and further shall secure and protect all Software  Products and
Documentation consistent with maintenance of SiRF's proprietary rights therein.

5.2 Additional Sublicensing Restrictions.  In addition to other restrictions set
forth in this Agreement, Licensee shall not sublicense a Software Product or any
portion of a Software Product  incorporated  into a GPS Product without entering
into a written agreement with the sublicensee that imposes the same restrictions
on the sublicensee as are placed on the Licensee by this Agreement.

5.3 ' Inclusion of Proprietary Notice. Licensee agrees to, and shall require any
sublicensees  to, include in the user  interface for each GPS Product,  a pop-up
screen containing SiRF's  proprietary  notice, in the form provided in Exhibit B
of this Agreement.  The pop-up screen shall be similar in frequency and location
of appearance,  size, position,  clarity and length of time it is visible on the
screen as Licensee's own such proprietary notice screen. SiRF may modify Exhibit
B from time to time upon thirty (30) days notice to Licensee.

5.4 Retention of Proprietary Notices. Licensee agrees not to remove, obliterate,
or  cancel  from  view  any  copyright,  trademark,   confidentiality  or  other
proprietary  notice, mark or legend appearing on any of the Software Products or
on output generated by the Software  Products and shall include the same on each
copy of the Software Products.

5.5 Mark  Ownership.  Nothing  contained in this Agreement shall be construed as
conferring any license or right with respect to any trademark, trade name, brand
name,  or the  corporate  name of  SiRF,  or of -any of  SiRF's  suppliers.  Any
goodwill  gained  from the use of such  marks  and  names  will  inure to SiRF's
benefit.

6. Confidentiality.  "Confidential Information" shall mean any and all technical
and non-technical documents and information including patent,  copyright,  trade
secret  and  proprietary  information,   techniques,  algorithms,  and  software
programs related to SiRF's current,  future and proposed  products and services,
and  includes,  without  limitation,  SiRF's  information  concerning  research,
engineering,  financial  information,   procurement  requirements,   purchasing,
manufacturing,  customer lists, business forecasts, sales and merchandising, and
marketing plans and information.



<PAGE>



Licensee  agrees to  maintain in  confidence  SiRF's  Confidential  Information.
Licensee  shall at all times,  both during the term of this  Agreement and for a
period of five (5) years  after its  termination,  keep in  confidence  all such
Confidential  Information,  and  shall  not use  such  Confidential  Information
without  SiRF's  written  consent except in performance of its duties under this
Agreement. Licensee will not disclose the Confidential Information to any person
except its  employees  to whom it is  necessary  to  disclose  the  Confidential
Information  for purposes  permitted under this Agreement and who have agreed in
writing to receive it under terms at least as restrictive as







<PAGE>



those  specified in this Agreement.  Licensee will take  reasonable  measures to
maintain the confidentiality of the Confidential Information, but -not less than
the measures it uses for its confidential  information of similar type. Licensee
will  immediately  give notice to SiRF of any  unauthorized use or disclosure of
the Confidential  Information.  Licensee agrees to assist SiRF in remedying such
unauthorized use or disclosure of the Confidential Information.

This obligation will not apply to the extent that Licensee can demonstrate:

      (a)   the disclosed information at the time of disclosure is
Part of the public domain;  -

(b) the disclosed  information  became part of the public domain, by publication
or otherwise, except by breach of the provisions of this Agreement;

(c) the disclosed  information  can be established  by written  evidence to have
been in the possession of the Licensee at the time of disclosure or to have been
independently  developed by Licensee's employees who did 'not have access to the
Confidential Information; or

(d) Licensee received the disclosed information  independently of this Agreement
from a third party without any obligation of confidence.

7. Injunctive Relief. Licensee acknowledges that the unauthorized use, transfer,
sublicensing  or disclosure of the Software  Products,  Documentation  or copies
thereof may cause irreparable  injury to SiRF, and under such circumstances SiRF
shall  be  entitled  to  equitable  relief,   including,  but  not  limited  to,
preliminary and permanent injunctive relief and Licensee waives any requirements
that a bond be posted.

8. Limited Warranty; Infringement. SiRF represents and warrants to Licensee that
it is the sole owner of the  Software  Product,  or has  procured  the  Software
Product under valid licenses from the owners  thereof,  and SiRF  represents and
warrants  that it has full  power  and  -authority  to grant the  rights  herein
granted  without  the  consent  of any other  person  and as of the date of this
Agreement  it has no  knowledge  that the  Software  Products  or  Documentation
infringe or otherwise make unauthorized use of any patent, copyright,  trademark
or trade secret of any party.

8.1 Remedy for Infringement.  If a court of competent  jurisdiction rules that a
Software Product infringes upon the copyright,  trademark or trade secret rights
of a third party,  SiRF shall,  at its option,  obtain a license from that third
party,  modify or replace the infringing  Software  Product with  non-infringing
software of similar functionality,  or accept the return of the Software Product
from  Licensee and refund to Licensee all amounts that Licensee paid to SiRF for
the Software  Products.  This remedy for  infringement  is Licensee's  exclusive
remedy, and Licensee hereby waives all other remedies, rights, causes of actions
and claims  against  SiRF and its  suppliers,  whether  in  contract,  tort,  by
statute,  or  otherwise,:  as well as any and all damages for  infringement  and
other indemnity,  whether direct,  consequential or otherwise.  THE WARRANTY AND
INDEMNITY  IN  THIS  SECTION  8 DO NOT  APPLY  TO USE OF  SOFTWARE  PRODUCTS  IN
COMBINATION WITH ANY OTHER PRODUCTS.


<PAGE>




9.
          Disclaimer and Limitation of Liability

9.1 Disclaimer of Warranties.  THE SOFTWARE  PRODUCTS AND  DOCUMENTATION AND ANY
AND ALL  UTD_A ES AND  MODIFICATIONS  TO THE SAME ARE  LICENSED  "AS IS" AND THE
WARRANTY PROVIDED IN SECTION 8 ABOVE IS THE SOLE AND EXCLUSIVE  WARRANTY OFFERED
BY SiRF. SiRF DOES NOT REPRESENT OR WARRANT THAT ERRORS IN THE SOFTWARE PRODUCTS
OR DOCUMENTATION WILL BE CORRECTED OR THAT THE SOFTWARE





<PAGE>



PRODUCTS WILL RUN ERROR-FREE.  EXCEPT AS SET FORTH IN SECTION 8 ABOVE, THERE ARE
NO  WARRANTIES  RESPECTING  THE  SOFTWARE  PRODUCTS,  DOCUMENTATION  OR SERVICES
PROVIDED  UNDER THIS  AGREEMENT,  EITHER  EXPRESS OR IMPLIED,  INCLUDING BUT NOT
LIMITED TO ANY WARRANTY OF DESIGN, MERCHANTABILITY,  OR FITNESS FOR A PARTICULAR
PURPOSE,  EVEN IF SiRF HAS BEEN  INFORMED OF SUCH PURPOSE,  OR WARRANTY  AGAINST
INFRINGEMENT'.  NO AGENT OF SiRF IS  AUTHORIZED  TO ALTER OR EXCEED THE WARRANTY
OBLIGATIONS OF SiRF AS SET FORTH IN THIS AGREEMENT.

9.2  Limitation of Remedies and Liability . SiRF SHALL NOT BE LIABLE TO LICENSEE
OR TO ANY OF LICENSEE'S  SUBLICENSEES,  CUSTOMERS,  OR END-USERS FOR ANY LOSS OF
PROFIT,  INDIRECT,  INCIDENTAL,  SPECIAL,  PUNITIVE,  OR  CONSEQUENTIAL  DAMAGES
ARISING OUT OF OR RELATING TO THE  LICENSING OR USE OF THE SOFTWARE  PRODUCTS OR
DOCUMENTATION  OR  FOR  ANY  ERROR  OR  DEFECT  IN  THE  SOFTWARE   PRODUCTS  OR
DOCUMENTATION.  The maximum  liability of SiRF  arising out of or in  connection
with any license,  use or other employment of any Software Product  delivered to
Licensee  under this  Agreement,  whether such  liability  arises from any claim
based on breach or repudiation of contract,  warranty, tort or otherwise,  shall
in no case exceed the greater of Fifty Dollars ($50) or the actual price paid to
SiRF by Licensee for the SiRF Chip whose license, use, or other employment gives
rise to the liability.

10. Licensee's Indemnification.  Licensee shall indemnify SiRF and its suppliers
and hold them harmless from any and all liabilities,  claims, costs, losses, and
expenses including,  but not limited to, reasonable attorneys' fees and costs of
suit incurred by SiRF or its suppliers,  or both,  arising out of or relating to
Licensee's  misuse,   modification,   upgrade,  additions,   alteration,   sale,
marketing,  reproduction,  sublicensing  or other  distribution  of the Software
Products or GPS Products.

11.
           Term and Termination.

11.1 Term of Agreement.  This Agreement shall be effective on the Effective Date
and shall continue in effect until  terminated in accordance  with the terms and
conditions of this Section 11.

11.2  Termination  by SiRF . If SiRF loses any of its rights as to any  Software
Product,  SiRF may  terminate  this  Agreement  with  respect  to such  Software
Product.

11.3 Breach.  Either party may terminate this  Agreement for material  breach by
providing  thirty (30) days written  notice to the breaching  party,  unless the
breach is corrected during such

,thirty (30) day period.  Material breach on the part of Licensee shall include,
but not be limited to,  failure to pay License Fees when due;  filing a petition
to declare such party insolvent or bankrupt which is not dismissed within thirty
(30)  days;  making  an  assignment  or other  arrangement  for the  benefit  of
creditors; or being dissolved or liquidated.



<PAGE>



11.4 Obligations on Termination.  Upon termination of this Agreement, all rights
granted by this  Agreement  shall  revert to SiRF and  Licensee  shall cease and
desist  all use of the  Software  Products  and  Documentation.  Licensee  shall
destroy or  deliver to SiRF  within  three (3) days of  termination  all full or
partial  copies  of  the  Software  Products  and  Documentation  in  Licensee's
possession  or under its  control,  other than  those  properly  distributed  by
Licensee  prior to  termination,  and will warrant to SiRF such  destruction  or
delivery. Licensee's failure to comply with the obligations of this Section 11.4
will constitute  unauthorized  use of the Software  Products and  Documentation,
entitling SiRF to equitable relief under Section 7 above and damages.

11.5 No Liability.  Neither  party shall be liable to the other for  terminating
this Agreement, other than termination by breach, in accordance with its terms.





<PAGE>



11.6  Survival.  The following  provisions of this  Agreement  shall survive its
termination: Sections 4, 5, 6, 7, 8, 9, 10, 11.4, 11.6, 14, 15, 16, 18 and 20.

12. Notices. All notices,  requests, and other communications in connection with
this Agreement  shall be deemed given (i) five days after being deposited in the
mail, postage pre-paid,  certified, or registered,  return receipt requested, or
(ii) one day after being sent by  overnight  courier,  charges  prepaid,  with a
confirming fax; and addressed as set forth below or to such other address as the
party to receive the notice or request so  designates  by written  notice to the
other.

If to SiRF:                       SiRF Technology Incorporated
                     3970 Freedom Circle
                     Santa Clara, California 95054
                     Attn: Vice President Marketing
                     Facsimile: (408) 980-4705

If to Licensee: To the address set forth on the Signature Page below

13.  Nonassignability.  Licensee  shall not assign or transfer this Agreement or
all or any part of-its  rights  hereunder,  by  operation  of law or  otherwise,
without the prior written  consent of SiRF,  except that Licensee may assign and
transfer all its rights under this Agreement solely to a  successor-interest  in
the event of a merger,  consolidation or sale of substantially all of Licensee's
assets or stock. Any unauthorized  assignment or transfer shall be null and void
and shall constitute a breach,  entitling SiRF to terminate this Agreement under
Section 11 above.  This  Agreement  shall inure to the benefit of and be binding
upon each party's permitted successors and assigns.

14.  Governing  Law,  Jurisdiction  and  Venue.  The  validity,  interpretation,
construction and performance of this Agreement shall be governed by the laws of,
the  State  of  California,  excluding  its  conflict  of laws  principles.  The
California state courts of Santa Clara County, California (or, if federal courts
have exclusive  jurisdiction,  the United States District Court for the Northern
District of  California)  shall have exclusive  jurisdiction  and venue over any
dispute  arising out of or  relating  to this  Agreement,  and  Licensee  hereby
consents to the jurisdiction  and venue of such courts.  Licensee shall file any
action  arising out of or relating to this  Agreement in the  appropriate  court
within one (1) year from the date that such cause of action accrues.

15. Export  Requirements.  The Software Products,  Documentation and all related
technical  information  or  materials  are  subject to export  controls  and are
licensable  under the U.S.  Government  export  regulations.  Licensee  will not
export,  re-export,  divert,  transfer or disclose,  directly or indirectly  the
Software  Products,  Documentation  and any  related  technical  information  or
materials  without  complying  strictly  with all legal  requirements  including
without  limitation  obtaining  the prior  approval  of the U.S.  Department  of
Commerce.  Licensee will execute and deliver to SiRF such "Letters of Assurance"
as may be required under applicable export regulations. Licensee shall indemnify
SiRF  against  any loss  related  to  Licensee's  failure  to  conform  to these
requirements.

16.        Compliance with Laws; Government GPS Limitations. Licensee agrees
that, in the marketing, distributing and sale of the GPS Products, it will
comply with, and that all GPS Products


<PAGE>



(and the  Software  Products  as  incorporated  therein)  will  conform  to, all
applicable federal,  state and local orders,  laws,  regulations and ordinances,
including  specifically United States federal government regulations relating to
GPS  technology.  Current  limitations on GPS  technology  known to SiRF include
those identified in Exhibit C hereto. Licensee shall defend,  indemnify and hold
SiRF harmless against any and all claims,  actions,  causes of action,  loss and
expenses arising out of

- -141.1


[GRAPHIC OMITTED]



<PAGE>



 Licensee's failure to abide by this Section 16.

17. U.S.  Government  Restricted Rights. The Software Products and Documentation
are provided with  Restricted  Rights.  Use,  duplication,  or disclosure by the
Government is subject to restrictions  as set forth in this Agreement,  pursuant
to DFARS 227-7202-3 or subparagraphs (c) (i) and (2) of the Commercial  Computer
Software-Restricted  Rights at 48 CFR 52.227-19, as applicable,  or as set forth
in the  particular  department or agency  regulations or rules that provide SiRF
with  protection  equivalent  to or greater  than the  above-cited  clause.  The
Manufacturer is SiRF Technology Incorporated,  3970 Freedom Circle, Santa Clara,
California 95054.

18. International  Transactions.  If the address of Licensee as set forth on the
signature  page of this Agreement is outside of the United States or if Licensee
is owned or controlled  by an entity whose  headquarters  or principal  place of
business  is  outside  of the  United  States,  then  the  following  additional
provisions shall apply:

18.1 This  Agreement is in the English  language  only,  which language shall be
controlling  in all  respects.  Any  versions  of this  Agreement  in any  other
language  shall be for  accommodation  only and shall not be binding upon either
party. All communications and Documentation to be furnished under this Agreement
shall be in the English language.

18.2 The rights and  obligations  of each party to this  Agreement  shall not be
governed by the provisions of the United Nations Convention on Contracts for the
International  Sale of Goods,  but  instead the  provisions  of Section 14 above
shall apply.

19. Severability. If any provision of this Agreement shall be held by a court of
competent  jurisdiction to be illegal,  invalid or unenforceable,  the remaining
provisions shall remain in full force and effect.

20.                                             Miscellaneous.

20.1 This Agreement contains the entire  understanding and agreement between the
parties respecting the subject matter hereof and all prior quotations, invoices,
negotiations,  understandings,  representations  -and agreements of the parties,
whether  oral or  written,  with  respect to the subject of this  Agreement  are
superseded in their entirety.

20.2 This  Agreement may not be  supplemented,  modified,  amended,  released or
discharged  except by an  instrument  in  writing  signed by each  party's  duly
authorized  representative or by Licensee opening an envelope  delivered by SiRF
containing computer media with the modifying terms written on the outside of the
envelope.

20.3 This  Agreement  shall  supersede in its  entirety  any  purchase  order of
Licensee for Software Products or Documentation and all such purchase orders are
subject  to  acceptance  by SiRF.  In no event  will any  additional  terms  and
conditions on a purchase order be effective unless expressly accepted by SiRF in
writing.



<PAGE>



20.4 If any action at law or in  equity,  including  an action  for  declaratory
relief or injunctive relief is brought to enforce or interpret the provisions of
this Agreement,  the prevailing party shall be entitled to reasonable attorneys,
fees in addition to any other relief to which the party may be entitled.

20.5 All captions and headings in this Agreement are for purposes of convenience
only and shall not  affect  the  construction  or  interpretation  of any of its
provisions.

20.6 Any waiver by either  party of any  default or breach  hereunder  shall not
constitute  a waiver of any  provision of this  Agreement  or of any  subsequent
default or breach of the same or a different kind.

The Effective Date of this Agreement is 11/6/98



IN  WITNESS   WHEREOF,   the   parties   have  caused   their  duly   authorized
representatives  to execute and deliver this  Agreement as of the date first set
forth above.

SiRF TECHNOLOGY INCORPORATED           LICENSEE

By

Title                                      Title

      Address


      Ship Software to:

                                               Contact Name

                                               Company
                                               Address
                                          City, State,Country
                                               Zip (Mail Code)
                                          Telephone
                                          Facsimile

I



<PAGE>



                                  EXHIBIT A
                              SOFTWARE PRODUCTS

SiRstarTM  GSW1 - SiRF's modular GPS receiver  software  SiRFdemo  Windows
Demo Software SirFdemo Windows Demo Software I




<PAGE>



                                  EXHIBIT B
                           SiRF PROPRIETARY NOTICE

        This system includes the SiRFstarTM Global Positioning System

(GPS) solution. Copyright @1995 SiRF Technology, Inc. All rights reserved.
SiRF is a registered trademark and SiRFstar is a trademark of SiRF Technology,
Inc.





<PAGE>



                                  EXHIBIT C
                          GOVERNMENT GPS LIMITATIONS
                             as of April 1, 1997

                      Velocity of less than 1,000 knots

                      Altitude of less than 60,000 feet




<PAGE>



SOURCE CODE
AMENDMENT TO BINARY SOFTWARE LICENSE AGREEMENT


THIS SOURCE CODE AMENDMENT TO BINARY SOFTWARE LICENSE AGREEMENT
("Amendment")  is entered  into and  effective as of the  Effective  Date by and
between SiRF TECHNOLOGY INCORPORATED,  a California corporation,  having offices
at 3970 Freedom Circle,  Santa Clara,  California  95054 ("SiRF") and the entity
identified on the licensee signature line .("Licensee").

                                   RECITALS

      A. SiRF and Licensee have executed and delivered a Binary Software License
Agreement  dated 11/10/98 (the "Binary  Agreement"),  under which SiRF granted I
Licensee a nonexclusive  license to distribute the Binary Software  Products and
Documentation  as  defined  and on the  terms and  conditions  set forth in such
Agreement.


     B. SiRF desires to grant to Licensee  and  Licensee  desires to obtain from
SiRF a  non-exclusive  license to use the  source  code for the whole or part of
Software Products as identified in Exhibit A to this Amendment.

NOW THEREFORE, the parties to this Amendment agree as follows:

1. Amendments to Binary  Agreement.  Subject to the terms and conditions of this
Amendment,  SiRF and Licensee hereby modify the Binary  Agreement to include the
source code of the Software Products by amending the Binary Agreement to include
the following sections:


"Software  Products" in the Binary Agreement shall include source code
as provided hereunder.

All other provisions of the Binary Agreement remain in full force and effect.

2.1 Grant of Rights to Source Code Format.  Subject to the terms and  conditions
of  the   Agreement,   SiRF  hereby  grants  and  Licensee   hereby   accepts  a
non-exclusive, nontransferable license to use and modify the source code for the
Software  Products  solely to improve the  performance  and to make the Software
Products  compatible  with the GPS Product in which the SiRF Chips are included.
Licensee  shall have no right to otherwise use or modify the Software  Products.
Licensee shall have no right to disclose,  sublicense, export, sell or otherwise
distribute  the Software  Products or any portion  thereof in source code format
nor shall Licensee authorize other parties to market, reproduce, have reproduced
or otherwise  manufacture  the Software  Products or GPS Products in source code
format.

2.2       Payment and Delivery of Source Code Software Products. Licensee shall
pay to SiRF within thirty (30) days of the Effective Date of this Amendment, the
License Fee set forth in Exhibit


<PAGE>



B to this  Amendment.  Within ten (10) days of SiRF's  receipt of the applicable
license fee as set forth above,  SiRF shall  deliver to Licensee the source code
for the applicable Software Products, together with related Documentation.  SiRF
shall  deliver  the  foregoing  in  electronic  files or  recordable  media (for
example, on diskette), at SiRF's option.

5.6 Copies.  Licensee  shall not copy the source code of the Software  Products,
except that Licensee may make one copy of the source code solely for archival or
backup  purposes  and may make  copies  of the  source  code  solely  for use by
Licensee's  employees  who have a need to use such source code for the  purposes
authorized under this Agreement.  All source code of the Software Products shall
remain on Licensee's business premises

6.1 Source Format.  Licensee acknowledges and agrees that all source code of the
Software  Products  is  SiRF  Confidential   Information.   However   Licensee's
confidentiality  obligations  for  source  code  of  Software  Products  survive
indefinitely.

The Effective Date of this Amendment is

IN  WITNESS   WHEREOF,   the   parties   have  caused   their  duly   authorized
representatives  to execute and deliver this  Agreement as of the date first set
forth above.

SiRF TECHNOLOGY INCORPORATEDLICENSEE

By                                  By
Title                           Title
                                Address

                                                    Ship Software to:

                                                    Contact Name

                                   Company

                                   Address

                             City, State, Country

                                Zip Mail Code)

                                                   Telephone
                                                   Facsimile




                             EMPLOYMENT AGREEMENT

THIS AGREEMENT, made and entered into this I st day of February 1999, between
Advanced Business Sciences, Inc., a Delaware corporation, ("Company") and
Benjamin J. Lamb, ("Executive").

WITNESSETH:
WHEREAS,  Company  is  engaged  in the  business  (the  "Company  Business")  of
Technology design,  monitoring,  tracking,  and mapping of individuals under the
control of the Criminal  Justice  Industry,  and other market segments as deemed
appropriate, and

WHEREAS,  the parties  hereto  desire to enter into an agreement  for  Company's
employment of Executive on the terms and conditions contained herein;

NOW THEREFORE, for and in consideration of the premises and the mutual covenants
and agreements  contained herein and for other good and valuable  consideration,
the receipt and sufficiency of which are hereby acknowledged, the parties hereto
agree as follows:

1 .  Employment  and  Duties.  Subject  to the  terms  and  conditions  of  this
Agreement,  Company  hereby  employs  Executive,  and Executive  hereby  accepts
employment with Company.  Executive will have such duties of an executive nature
as are assigned to him from time to time and will serve as President  and CEO of
Company.  Executive shall report to the Chairman of the Board of the Company and
shall be appointed and serve as a voting Director of the Company.

2. Term.  Executive's employment pursuant to this Agreement shall commence as of
the date hereof and shall  continue  through the third  anniversary  of the date
hereof  ("the  Expiration  Date").   After  the  Expiration  Date,   Executive's
employment  hereunder  shall renew  annually  and continue on the same terms and
conditions  for an indefinite  term,  unless and until  terminated in accordance
with Section 7.

3. Time Commitment. During the Term, Executive shall devote substantially all of
his  business  time,  attention  and  energies  to  the  diligent  and  faithful
performance  of his duties as an executive  employee of the  Company.  Executive
shall not, without the prior written consent of Company,  at any time during the
Term: (a) accept employment with, or render services of a business, professional
or commercial nature to, any other Person (as defined below);  (b) engage in any
venture or activity  which Company may in good faith  consider to be competitive
with or adverse to the Company Business,  whether alone or with any other Person
as a partner, officer, director, employee, agent, shareholder,  consultant sales
representative  or  otherwise,  except that the ownership of not more that 3% of
the shares or other  equity  interests  of any Person  which is publicly  traded
shall not be deemed a violation  of this Section 3; or (c) engage in any venture
or activity  which the Board of Directors of Company may in good faith  consider
to interfere with Executive's  performance of his duties  hereunder.  As used in
the Agreement,  "Person" means any individual,  corporation,  limited  liability
company, bank,  partnership,  joint venture,  association,  joint-stock company,
trust,  unincorporated   organization  or  other  entity.   Notwithstanding  the
foregoing, Company acknowledges and agrees to


<PAGE>



allow Executive to continue his ownership and  officer/director  roles in INTECK
Corporation,  so long as it does  not  have a  material  adverse  affect  on his
obligations in this Agreement.

4.7.  Options.  Company  shall grant to Executive on the date hereof  options to
purchase 8.0% Common Stock of the Company as shown on the Company as of February
1, 1999 at a share value of ten cents (.10) per share.  An option  agreement  to
provide for vesting and exercise schedule for these shares shall be:

Block 1: One third of such options shall become vested and exercisable beginning
the  earlier of  December  30, 1999 or when the closing bid price for the common
shares of ABS  exceeds  $3.00 per share for at least  five  consecutive  trading
days. The options shall remain  exercisable for a period of three years from the
date of vesting.

Block 2: One third of such options shall become vested and exercisable beginning
the  earlier of  December  30, 2000 or when the closing bid price for the common
shares of ABS  exceeds  $4.00 per share for at least  five  consecutive  trading
days. The options shall remain  exercisable for a period of three years from the
date of vesting.

Block 3: One third of such options shall become vested and exercisable beginning
the  earlier of  December  30, 2001 or when the closing bid price for the common
shares of ABS  exceeds  $6.00 per share for at least  five  consecutive  trading
days. The options shall remain  exercisable for a period of three years from the
date of vesting.

Any blocks not yet vested  would vest and be  immediately  exercisable  upon the
occurrence of a sale or merger of ABS, which includes a transfer of control.

Company will pay the incurred  tax  liability  associated  with  exercising  the
options at each year-end vesting period.  If the Executive  voluntarily  resigns
from the  Company  during the initial 18 months of this  agreement,  Company can
repurchase all vested options at the option strike price. The repurchase must be
completed within 30 days of Executive's resignation.

Executive  will, if determined in the sole discretion of the Board of Directors,
be eligible to participate in the Company's  incentive option program(s) for key
employees as they are  instituted  from time to time.  All options  provided for
under this  paragraph 4.7 shall become  exercisable  immediately  upon a merger,
consolidation  or   reorganization  of  the  Company  with  one  or  more  other
corporations  in which the Company is not the surviving  corporation,  or upon a
sale of substantially  all of the assets of the Company to another  corporation,
or  upon  any  transaction   (including,   without   limitation,   a  merger  or
reorganization  in which the Company is the surviving  corporation)  approved by
the Board  which  results in any person or entity  (other  than  persons who are
holders  of  stock of the  Company  at the  time  the  plan is  approved  by the
stockholders  and other than an Affiliate) owing 60 percent or more the combined
voting power al all classes of stock of the Company.

3




<PAGE>



5.  Covenants of Executive.  Executive  understands  and agrees that the Company
Business is one which  makes it crucial for Company to develop and retain  trade
secrets customer lists,  proprietary techniques,  information regarding customer
needs and other confidential  information;  and acknowledges that Executive will
develop and learn such information in the course of his employment.  In light of
these facts and in  consideration  of  Executive's  employment  with Company and
Company's agreement to compensate  Executive on the terms set forth in Section 4
hereof, Executive covenants and agrees with Company as follows:

5.1 Covenant to Protect  Confidential  Information.  Without  limiting any other
obligation  Executive  may have  with  respect  to use or  nondisclosure  of any
information,  Executive shall protect all Company  Confidential  Information (as
defined  below) at all  times,  both  during  and after the Term,  and shall not
disclose to any Person,  or otherwise use,  except in connection with his duties
performed  in  accordance   with  this   Agreement   any  Company   Confidential
Information.  For purposes of the Agreement,  "Company Confidential Information"
means technical,  business and other  information of Company,  whether or not in
writing,  which derives value from not being generally known to the public or to
other  Persons  who can obtain  value  from its  disclosure  or use,  including,
without  limitation,  technical or  nontechnical  data,  compositions,  devices,
methods, techniques, drawings, inventions,  processes, financial data, financial
plans,  product  plans,  lists or  information  concerning  actual or  potential
customers or suppliers,  information  regarding  business plans and  operations,
methods and plans of operation,  marketing  strategies,  sales and  distribution
plans or strategies,  cost information,  pricing strategies, and acquisition and
investment  plans.   Company   Confidential   Information  includes  information
disclosed by third  parties  that Company  treats or is obligated to maintain as
confidential.  The  foregoing  provision  shall  not  apply to any  confidential
information which is generally  available to the public immediately prior to the
time of disclosure.  The  restrictions of this Section 5.1 shall expire one year
after the  Termination  Date. As used in this Agreement the  "Termination  Date"
means the last day  Executive  is  employed by Company,  whether  separation  is
voluntary or involuntary and with or without cause.

5.2  Covenants  against  Competition.  Without  limiting  any other  restrictive
covenant or obligation to which  executive may be subject  hereunder,  under any
other agreement or under  applicable law,  Executive shall not, except on behalf
of Company or an affiliate of Company,  at any time during the period commencing
on the date of this  Agreement and continuing for the period set out below after
the  Termination  Date,  whether  alone or with any other  Persons as a partner,
officer, director, employee, agent, shareholder, consultant sales representative
or otherwise:

(a) for a period of one year  following  termination  from  employment,  without
cause,  Executive shall not engage in any business  activity that is competitive
with the business the Company was engaged in at time of Executive's termination.
In consideration of the initial one-year period of  noncompetition  as described
in this section,  Executive shall receive the  compensation set out in Paragraph
7.2(c).




<PAGE>



(b) for a period of two years  following  termination,  for any reason,  whether
with or without cause,  whether  voluntary or  involuntary,  Executive shall not
solicit or assist in the  solicitation  of any  customer  who is, at the time of
Executive's  termination  from  employment  with  Company,  for the  purpose  of
obtaining the patronage of such customer for purposes  which are  competitive to
those of the Company at the time of Executive's termination.

(c) for a period  of one  year  following  termination  of  employment,  for any
reason,  whether  with or  without  cause,  whether  voluntary  or  involuntary,
Executive  shall not  solicit  or  assist in the  solicitation  of,  any  Person
employed by Company in any capacity (including without limitation as an employee
or independent  contractor),  to terminate such employment,  whether or not such
Person is employed  pursuant to a contract  with Company and whether or not such
Person is employed at will.

      The foregoing  provisions of this Section 5.2 shall not prohibit Executive
from owning,  not to exceed 3%, of the outstanding  stock on any publicly traded
corporation that might be deemed a competitor of the Company.

6.  Inventions, Copyrights, Etc.

6.1  Inventions.  - Executive  shall  disclose  promptly to Company (which shall
receive  it in  confidence),  and only to  Company,  any  invention  or ideas of
Executive  (developed alone or with others) conceived or made during Executive's
employment  by Company  any such  invention  or idea in any way  connected  with
Executive's   employment   or  related  to  Company's   business,   research  or
development,  or  demonstrably  anticipated  research or  development,  and will
cooperate  with Company and sign all  documents  deemed  necessary by Company to
enable  it to  obtain,  maintain,  protect  and  defend  patents  covering  such
inventions and ideas and to confirm Company's  exclusive ownership of all rights
in such inventions,  ideas and patents,  and irrevocably appoints Company as his
agent to execute and deliver any  assignments  or documents  Executive  fails or
refuses to execute and deliver  promptly,  this power and agency  being  coupled
with an interest  and being  irrevocable.  This  constitutes  Company's  written
notification  that this  assignment  does not apply to an invention for which no
equipment,  supplies,  facility or trade secret  information of Company was used
and which was  developed  entirely  on  Executive's  own  time,  unless  (a) the
invention relates (i) directly to the business of Company,  or (ii) to Company's
actual or demonstrably anticipated research or development, or (b) the invention
results from any work performed by Executive for Company.

6.2 Work for  Hire  Acknowledgement;  Assignment.  Executive  acknowledges  that
Executive's  work on and  contributions  to documents and other  expressions  in
tangible media relating to the business of the Company  (collectively,  "Works")
are within the scope of Executive's  employment  and part of Executive's  duties
and responsibilities  for Company and its affiliates,  and are, and at all times
shall be  regarded  as,  "work made for hire" as that term is used in the United
States Copyright Laws. Without limiting this  acknowledgment  Executive assigns,
grants and delivers exclusively to Company all rights,  titles, and interests in
and to any such Works, and all copies and versions, including all copyrights and
renewals,  Executive  will execute and deliver to Company,  its  successors  and
assigns,  any  assignments  and  documents  Company  requests for the purpose of
establishing  evidencing,  and enforcing or defending  its complete,  exclusive,
perpetual and worldwide ownership of all rights, titles,


<PAGE>



and interest of every kind and nature,  including all copyrights,  in and to the
Works,  and Executive  constitutes and appoints  Company as its agent to execute
and deliver any  assignments or documents  Executive fails or refuses to execute
and  deliver,  this power and agency  being  coupled  with an interest and being
irrevocable.

6.3 Return of Company Documents and Equipment.  At the end of employment,  or at
any time upon Company's request, Executive shall deliver to Company all material
files,  customer  lists,  price lists,  bids,  specifications,  forms,  software
financial  data,  papers  and  other  documents,  including  all  copies  of the
foregoing  (including  those  contained  in  magnetic  media or  other  forms of
computer storage);  all computers,  modems,  diskettes,  samples,  credit cards,
keys, security passes, tools, vehicles and equipment and all other materials and
other property in his possession or control that relate to the Company  Business
or his employment with Company,  all of which at all times shall be the property
of Company unless otherwise agreed by Company in writing.

7.0  Termination.

7.1 By Either Party. Either party may terminate the Executive's employment under
this  Agreement,  with or without cause, by giving the other party not less than
thirty days advance written notice thereof.

7.2  Other  Terminations  Without  Cause.   Executive's  employment  under  this
Agreement  shall  terminate  immediately  upon  the  occurrence  of  one  of the
following events:

(a)  the death of Executive;

(b)  termination  by Company on written notice of  termination  after  Executive
becomes  unable to perform his services by reason of illness or which illness or
incapacity  results in his failure to discharge his duties under this  Agreement
for an aggregate total of 30 days (whether consecutive or nonconsecutive) during
any 90 day period; or

(c) termination of Executive's  employment by Company without cause at Company's
sole  discretion  on written  notice of  termination,  provided  that if Company
terminates  under this Section 7.2(c) Company shall pay to Executive his regular
salary (as determined by the amount  Executive is paid on an annual basis during
his final year of employment)  for a period of one year,  following  termination
from  employment.  This  salary  continuation  for a period of one year shall be
consideration for enforcement of the nondisclosure  provisions of Section 5. and
the noncompetition  provisions of Section 5.2(a) and Section 6 hereof. Executive
shall  continue  to receive his salary for a period of one year from the date of
termination  under this Section but without any other employee benefits received
by Executive prior to his termination.  The foregoing  provision is not intended
to and shall not extend any period  during which  Executive  may be eligible for
any post employment benefits under any benefit plan, applicable law,



<PAGE>



or otherwise,  Executive's  employment ending and any such period commencing for
all  purposes  on  the  Termination  Date  set  forth  in  Company's  notice  of
termination under this Section 7.2(c).

7.3 By Executive  for Cause.  Executive  shall have the right to  terminate  his
employment  under this  agreement  on written  notice to Company and receive the
salary  set forth in  Section  7.2(c) if  Company  has:  (a)  failed to make any
payments due to  Executive  under this  Agreement  and such failure has not been
cured within thirty days after written  notice of such failure from Executive to
Company, or (b) otherwise materially breached this Agreement and such breach, if
capable of cure,  has not been cured within thirty days after written  notice of
such breach from Executive to Company.

7.4 By Company for Cause. The Executive's employment may be terminated effective
immediately  by  the  Company  for  "cause"  by  notice  of  termination  to the
Executive.  "Cause" for such termination  shall include,  but not be limited to,
the  following:  (i)  Dishonesty of the Executive with respect to the Company or
any of its  subsidiaries;  (ii)  Willful  misfeasance  or  nonfeasance  of  duty
intended to injure or having the effect of injuring the reputation,  business or
business relationships of the Company or any of its subsidiaries or any of their
respective officers,  directors or employees;  (iii) Conviction of the Executive
upon a charge of any crime  involving  moral  turpitude  or which could  reflect
unfavorably  upon  the  Company  or any of its  subsidiaries;  (iv)  Willful  or
prolonged absence from work by the Executive (other than by reason of disability
due to  physical  or mental  illness)  or  failure,  neglect  or  refusal by the
Executive  to perform  his duties and  responsibilities  without  the same being
corrected  upon ten  (10)  days  prior  written  notice:  or (v)  Breach  by the
Executive of any of the covenants contained in this agreement.

8. Other Employees.  Nothing in this Agreement shall limit Company's  discretion
to employ other  personnel on such terms and conditions and for such position as
may be satisfactory to Company.

9.  Insurance.  Company may obtain,  in the name and for the benefit of Company,
such life, disability,  and other insurance policies on Executive as Company may
from time to time  determine to be in the interest of Company.  Executive  shall
take such medical and physical  examinations which Company may from time to time
reasonable request,  including any examination required to obtain such insurance
policies.

10. No Conflicting Obligations. Executive represents and warrants that he is not
subject to any noncompetition  agreement,  nondisclosure  agreement,  employment
agreement, or any other contract of any nature whatsoever, oral or written, with
any  Person  other than  Company,  which will cause a breach of or default in or
which  is in any  way  inconsistent  with,  the  terms  and  provisions  of this
Agreement except as noted in Section 3.

11. Notice to Future  Employers.  If Executive  leaves the employ of Company for
any reason, (a) Executive shall,  during the two years following  termination of
Executive's employment with Company, inform any subsequent employers or business
partners of the existence and  provisions of this  Agreement  and, if requested,
provide a copy of this



<PAGE>



Agreement  to such  employer or business  partner,  and (b) Company  may, at any
time,  notify any future  employer  or  business  partner  of  Executive  of the
existence and provisions at the Agreement.

12.  Miscellaneous.  This Agreement shall inure to the benefit of and be binding
upon  Company,  and its  successors  and assigns,  and  Executive and his heirs,
executors,  administrators and personal representatives.  This Agreement may not
be  assigned by  Executive  or by  Company,  except that  Company may assign its
rights  under this  Agreement  without the written  consent of  Executive to any
affiliate of Company  providing  services to Company or in  connection  with any
transfer of Company or of any substantial part of the Company Business (and such
assignment  shall not  constitute a  termination  of  Executive's  employment by
Company for purposes of the Agreement);  provided,  however, that such affiliate
or transferee  shall be obligated to perform this  Agreement in accordance  with
its terms.

12.1 Entire Agreement. This Agreement,  including any attachments,  contains the
entire agreement  between the parties and no statement,  promises or inducements
made by either party hereto, or agent of either party hereto, or agent of either
party, which is not contained in this Agreement,  shall be valid or binding; and
this  Agreement may not be enlarged,  amended,  modified or altered  except in a
writing  signed by Company  and  Executive  and  specifically  referencing  this
Agreement.  Commencement of Executive's  employment  hereunder shall constitute,
automatically  and without  further action by the parties,  a termination of any
existing  employment  agreement  between  Executive and Company effective on the
date of such event, provided that salary and other rights and obligations of the
parties  accrued under any such  agreement  prior to the  effective  date hereof
shall not, except as otherwise  expressly  provided herein,  be affected by such
termination and shall be paid or satisfied when due in the ordinary course.  The
provisions  of this  Agreement  do not in any way limit or abridge any rights of
Company or any  affiliate  under the laws of unfair  competition,  trade secret,
copyright,  patent,  trademark or any other applicable laws, all of which are in
addition to and cumulative of the rights of Company under this Agreement.

12.2 Provisions Severable. If any provision or covenant, or any part thereof, of
this  Agreement  should  be  held  by  any  court  to  be  invalid,  illegal  or
unenforceable,  either in whole or in part, then such invalidity,  illegality or
unenforceability  shall not affect the validity,  legality or  enforceability of
the remaining  provisions or covenants,  or any part thereof, of this Agreement,
all of which  shall  remain  in full  force and  effect.  Without  limiting  the
foregoing,  although the parties have, in good faith, used their best efforts to
make the covenants in Section 5 reasonable in all respects and do not anticipate
or intend that any court of competent  jurisdiction  would conclude otherwise or
would find it necessary or appropriate to reform any such covenant,  if any such
covenant  is held by a  court  of  competent  jurisdiction  to be  unreasonable,
arbitrary or against  public  policy,  such  covenant  will be  considered to be
divisible  with  respect to scope,  time and  geographic  area,  and such lesser
scope,  time,  and  geographic  area,  or all of them,  as a court of  competent
jurisdiction  may determine to be  reasonable,  not  arbitrary,  and not against
public policy, will be effective, binding and enforceable against Executive.

12.3 Remedies. Executive acknowledges that if he breaches or threatens to breach
his  covenants  and  agreements  in this  Agreement,  then his actions may cause
irreparable harm and damage to Company which could not be adequately compensated
in damages. Accordingly, if Executive breaches or


<PAGE>



threatens to breach this Agreement, then Company shall be entitled to injunctive
relief,  in addition to any other  rights or  remedies of Company  hereunder  or
otherwise.  Upon any breach of this  Agreement  by Company,  Executive  shall be
entitled to such rights and remedies as may be allowed by law or in equity.

12.4 Waiver.  Failure of either party to insist,  in one or more  instances,  on
performance by the other in strict  accordance  with the terms and conditions of
this  Agreement  shall  not be deemed a waiver  or  relinquishment  of any right
granted  in this  Agreement  or of the  future  performance  of any such term or
condition  or of any other term or  condition  of this  Agreement,  unless  such
waiver is  contained  in a writing  signed by the party  making  the  waiver and
specifically referencing this Agreement.

12.5 Notices. All notices and other  communications  required or permitted to be
given or made  hereunder  shall be in writing and sent by  pre-paid  first class
certified  or  registered  mail,  return  receipt  requested,  or  by  facsimile
transmission,  to the  intended  recipient  thereof  at his  or its  address  or
facsimile  number  set forth  below or last  designated  address  and  facsimile
number:

If to Company:
Advanced Business Sciences, Inc.
Attention: Chairman of Board
3345 North 107th Street
Omaha, Nebraska 68134
Facsimile No:(402) 498-8812

If to Executive:
Benjamin J. Lamb
609 Olson Drive
Papillion, Nebraska 68046

Facsimile No.(402) 593-7154

Any such  notice or  communication  shall be  deemed  to have  been  duly  given
immediately  (if given by  facsimile  confirmed by mailing a copy thereof to the
recipient in accordance  with this Section 12.6 on the date of such  facsimile),
or three days after  mailing (if given or made by mail),  and in proving same it
shall be sufficient to show that the envelope  containing the same was delivered
to the delivery or postal  service and duly  addressed,  or that  recipient of a
facsimile was confirmed by the recipient as provided above.  Any Person entitled
to notice may change the address(es) or facsimile  number(s) to which notices or
other communications to such Person shall be delivered, mailed or transmitted by
giving notice thereof to the parties hereto in the manner  provided  herein.  No
notice or  communication to Company shall be deemed complete unless also made to
Advanced Business Sciences, Inc., in accordance with this Section 12.5.

12.6.  Survival.  Executive's  obligations  pursuant  to  Sections 5 and 6 shall
survive the  Termination  Date and any  termination  of this  Agreement  for the
period(s) therein provided. Except as expressly provided above in Section 7.2(c)
or as required by law or the express terms of any employee benefit


<PAGE>



plan  in  which  Executive  participates,   neither  Executive  nor  his  heirs,
executors, administrators or personal representatives,  shall be entitled to any
salary,  bonus or other  compensation  or any benefits  during or for any period
after the Termination date.

12.7. Counterparts. This Agreement may be executed simultaneously in two or more
counterparts,  each of which  shall be deemed an  original,  and it shall not be
necessary in making proof of this  Agreement to produce or account for more than
on such counterpart.

12.8.  Headings.  Section and other headings contained in this Agreement are for
reference  purposes  only  and  are in no way  intended  to  define,  interpret,
describe or otherwise limit the scope, extent or intent of this Agreement or any
of its provisions.

12.9. Withholding . Anything in this Agreement to the contrary  notwithstanding,
all payments  required to be made by Company  hereunder  to  Executive  shall be
subject to the  withholding  of such  amounts  relating  to taxes as Company may
reasonably  determine  it should  withhold  pursuant  to any  applicable  law or
regulation.

12.10.  Governing  Law.  This  Agreement and the rights and  obligations  of the
parties  hereunder shall be governed by and construed and enforced in accordance
with the laws of the State of  Nebraska,  without  regard to its  principles  of
conflicts of law.

IN WITNESS  WHEREOF,  the parties have executed this Agreement as of the day and
year first above written.

EXECUTIVE
Name - Benjamin J. Lamb

- ------------------------------------------------
- --------------
Signature       Date


COMPANY:
Avanced Business Sciences, Inc.

BY___________________________________________
 Title                   Date





                            SUBSIDIARIES OF COMPANY


ABS NEBRASKA, INC., a Nebraska corporation





                            Schaneveldt and Company
                          Certified Public Accountant
                        275 E. South Temple, Suite 300
                          Salt Lake City, Utah  84111
                                (801) 521-2392


I have  issued my report  dated June 7, 1999,  on the  financial  statements  of
Advanced  Business  Sciences,  Inc.,  for the year ended  December  31,  1998. I
consent to the use of our report in the filing of  Advanced  Business  Sciences,
Inc. on Form 10SB. I also consent to the use of my name and the statements  with
respect to me as  appearing  under the  heading  "PART F/S" in the  Registration
Statement.

/s/ Schvaneveldt and Company


Salt Lake City, Utah
June 21, 1999

<TABLE> <S> <C>


<ARTICLE>                     5

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<PERIOD-TYPE>     3-MOS
<FISCAL-YEAR-END> DEC-31-1998
<PERIOD-START>    JAN-01-1999
<PERIOD-END>      MAR-31-1999
<CASH>   12,057
<SECURITIES>      0
<RECEIVABLES>     50,846
<ALLOWANCES>      0
<INVENTORY>       654,389
<CURRENT-ASSETS>  1,445,294
<PP&E>   936,977
<DEPRECIATION>    398,551
<TOTAL-ASSETS>    2,092,129
<CURRENT-LIABILITIES>      3,408,333
<BONDS>  0
      0
       0
<COMMON> 13,286
<OTHER-SE>        (1,452,854)
<TOTAL-LIABILITY-AND-EQUITY>        2,092,129
<SALES>  48,869
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<EPS-BASIC>     0.06
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<TABLE> <S> <C>


<ARTICLE>                     5

<S>                             <C><PERIOD-TYPE>     12-MOS
<FISCAL-YEAR-END> DEC-31-1998
<PERIOD-START>    JAN-01-1998
<PERIOD-END>      DEC-31-1998
<CASH>   377,592
<SECURITIES>      0
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      0
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