BIOSYNTECH INC
PRE 14A, 2000-10-13
NON-OPERATING ESTABLISHMENTS
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                                  SCHEDULE 14A
                                 (Rule 14a-101)

                     INFORMATION REQUIRED IN PROXY STATEMENT

                            SCHEDULE 14A INFORMATION

                    Proxy Statement Pursuant to Section 14(a)
             of the Securities Exchange Act of 1934 (Amendment No. )


Filed by the registrant /X/

Filed by a party other than the registrant / /

Check the appropriate box:

         /X/      Preliminary Proxy Statement
         / /      Confidential,  for Use of the Commission Only (as permitted by
                  Rule 14a-6(e)2))
         / /      Definitive Proxy Statement
         / /      Definitive Additional Materials
         / /      Soliciting   Material  Pursuant  to  Rule  14a-11(c)  or  Rule
                  14(a)-12


                                BIOSYNTECH, INC.
--------------------------------------------------------------------------------
                  (Name of Registrant as Specified in Charter)



--------------------------------------------------------------------------------
      (Name of Person(s) filing Proxy Statement, if other than Registrant)


         Payment of filing fee (check the appropriate box):

         /X/      No fee required.

         / /      Fee computed on table below per Exchange Act Rules 14a-6(i)(1)
                  and 0-11.

         (1)      Title  of  each  class  of  securities  to  which  transaction
                  applies:

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         (2)      Aggregate number of securities to which transaction applies:

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<PAGE>

         (3)      Per  unit  price  or other  underlying  value  of  transaction
                  computed  pursuant  to  Exchange  Act Rule 0-11 (Set forth the
                  amount on which the filing fee is calculated  and state how it
                  was determined):


--------------------------------------------------------------------------------



         (4)      Proposed maximum aggregate value of transaction:


--------------------------------------------------------------------------------





         (5)      Total fee paid:


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         / /      Fee paid previously with preliminary materials.


         / /      Check  box if any part of the fee is  offset  as  provided  by
Exchange Act Rule  0-11(a)(2)  and identify the filing for which the  offsetting
fee was paid previously.  Identify the previous filing by registration statement
number, or the form or schedule and the date of its filing.

         (1)      Amount Previously Paid:



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         (2)      Form, Schedule or Registration Statement no.:



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         (3)      Filing Party:



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         (4)      Date Filed:




                                       -2-

<PAGE>

                                BIOSYNTECH, INC.
                          475 Boulevard Armand-Frappier
                          Laval, Quebec, Canada H7V 4B3

                                 --------------

                  NOTICE OF 2000 ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD NOVEMBER 30, 2000
                                 --------------

To the Holders of Common Stock of BioSyntech, Inc. and
       Holders of Exchangeable Preferred Stock of Bio Syntech Canada, Inc.:

         NOTICE IS HEREBY  GIVEN that the 2000  Annual  Meeting of  Stockholders
(the  "Annual  Meeting")  of  BioSyntech,   Inc.,  a  Nevada   corporation  (the
"Company"),  will  be held  at  [_________________________________________],  on
November 30, 2000 at 11:00 A.M., local time, for the following purposes:

                  1.   To approve  the  adoption  of the  Amended  and  Restated
                       Articles of Incorporation of the Company;

                  2.   To elect six members of the Board of Directors;

                  3.   To approve the  adoption of the  Company's  Stock  Option
                       Incentive  Plan  and Bio  Syntech  Canada,  Inc.'s  Stock
                       Option Incentive Plan;

                  4.   To  ratify  the  appointment  of Ernst & Young LLP as the
                       Company's independent auditors for the fiscal year ending
                       March 31, 2001; and

                  5.   To  transact  such  other  business  as may  properly  be
                       brought  before  the Annual  Meeting  or any  adjournment
                       thereof.

            The Board of  Directors  has fixed the close of  business on October
25, 2000 as the record date for the Annual Meeting (the "Record Date").  Holders
of record of Common  Stock on the stock  transfer  books of the  Company  at the
close of business on the Record Date are  entitled to notice of, and to vote at,
the Annual  Meeting.  In addition,  holders of record of shares of  exchangeable
preferred  stock of Bio Syntech  Canada,  Inc. as of the Record Date have voting
rights in that number of shares of the Company's Common Stock equal in number to
the number of shares of such exchangeable preferred stock held.

                                           By Order of the Board of Directors


                                           Anthony Casola
                                           Chief Financial Officer & Secretary

Dated: October 26, 2000
Laval, Quebec, Canada

WHETHER OR NOT YOU EXPECT TO BE PRESENT AT THE ANNUAL MEETING,  YOU ARE URGED TO
FILL IN,  DATE,  SIGN AND  RETURN THE  ENCLOSED  PROXY IN THE  ENVELOPE  THAT IS
PROVIDED.


<PAGE>

                     PRELIMINARY COPY SUBJECT TO COMPLETION
                             AS OF OCTOBER 13, 2000

                                BIOSYNTECH, INC.
                          475 Boulevard Armand-Frappier
                          Laval, Quebec, Canada H7V 4B3
                     --------------------------------------

                                 PROXY STATEMENT
                     --------------------------------------

                                  INTRODUCTION

            This Proxy  Statement is being furnished to the holders of shares of
common  stock,  $.001 par value (the "Common  Stock") of  BioSyntech  Inc.  (the
"Company") and the holders of exchangeable  preferred  stock (the  "Exchangeable
Shares") of the Company's  subsidiary,  Bio Syntech  Canada,  Inc. ("Bio Syntech
Canada") in connection with the solicitation of the  accompanying  Proxy for use
at the 2000 Annual Meeting of Stockholders of the Company (the "Annual Meeting")
to be held at  [____________________________],  on November 30,  2000,  at 11:00
a.m., and any adjournment thereof.

            The  approximate   date  on  which  this  Proxy  Statement  and  the
accompanying Proxy will first be sent or given to the Company's stockholders and
the holders of Exchangeable Shares is October 27, 2000.

                        RECORD DATE AND VOTING SECURITIES

            Only  holders of record of Common Stock and  Exchangeable  Shares at
the close of business on October 25, 2000,  the record date (the "Record  Date")
for the  Annual  Meeting,  will be  entitled  to notice  of, and to vote at, the
Annual Meeting and any adjournment  thereof.  As of the Record Date,  there were
[29,182,250]  shares of Common  Stock  outstanding,  which  includes  15,177,036
shares of Common  Stock that were issued in trust for the benefit of the holders
of Exchangeable Shares.

            The Company has only one class of voting shares.  All shares in this
class have one vote per share.  The  Exchangeable  Shares are  exchangeable on a
share-for-share  basis for an aggregate of  15,177,036  shares of Common  Stock,
which have been issued and are held in trust (the "Trust  Shares").  Each holder
of  Exchangeable  Shares has  voting  rights in that  number of Trust  Shares as
equals the number of Exchangeable Shares held by such holder.  References herein
to  "stockholders"  include  holders of  Exchangeable  Shares unless the context
otherwise requires.


                                VOTING OF PROXIES

            Stockholders represented by Proxies that are properly executed, duly
returned  and not  revoked  will be voted in  accordance  with the  instructions
contained  therein.  If no  specification  is indicated  in the Proxy,  all such
shares will be voted (i) for the adoption of the Amended and  Restated  Articles
of  Incorporation,  (ii) for  election as directors of the persons who have been
nominated by the Board of  Directors,  (iii) for approval of the adoption of the
Company's  Stock Option  Incentive Plan (the "BSYI Option Plan") and Bio Syntech
Canada's Stock Option  Incentive Plan (the "BSC Option Plan",  and together with
the BSYI Option Plan,  the "Option  Plans"),  (iv) for the  ratification  of the
appointment of Ernst & Young LLP as the Company's  independent  auditors for the
fiscal year ending  March 31, 2001 and (v) on any other matter that may properly
be brought  before the Annual  Meeting,  in accordance  with the judgment of the
person or persons voting the Proxies.

            The execution of a Proxy will in no way affect a stockholder's right
to attend  the Annual  Meeting  and to vote in person.  Any Proxy  executed  and
returned  by a  stockholder  may be  revoked at any time




<PAGE>

thereafter  if written  notice of  revocation  is given to the  Secretary of the
Company prior to the vote to be taken at the Annual Meeting,  or by execution of
a subsequent proxy that is presented to the Annual Meeting or if the stockholder
attends  the  Annual  Meeting  and votes by  ballot,  except as to any matter or
matters  upon  which a vote  shall  have been  cast  pursuant  to the  authority
conferred by such Proxy prior to such revocation.

            The cost of solicitation of the Proxies being solicited on behalf of
the Board of Directors  will be borne by the Company.  In addition to the use of
the mails, proxy  solicitation may be made by telephone,  telegraph and personal
interview by officers, directors and employees of the Company. The Company will,
upon request, reimburse brokerage houses and persons holding Common Stock in the
names of their  nominees  for their  reasonable  expenses in sending  soliciting
material to their principals.

                                  VOTES NEEDED

            The holders of a majority of the outstanding shares of Common Stock,
whether present in person or represented by proxy,  will constitute a quorum for
each of the matters  identified in the notice of the Annual Meeting,  as well as
for any other matters that may come before the Annual Meeting.

            Broker "non-votes" and the shares as to which a stockholder abstains
from voting are included for purposes of determining  whether a quorum of shares
is present at a  meeting.  A broker  "non-vote"  occurs  when a nominee  holding
shares for a beneficial owner does not vote on a particular proposal because the
nominee does not have  discretionary  voting power with respect to that item and
has not received  instructions  from the beneficial  owner.  Brokers that do not
receive  instructions from the stockholders are entitled to vote on the election
of directors and the ratification of the auditors.

            The  affirmative  vote of a majority  of the  outstanding  shares of
Common  Stock is required to approve  the  adoption of the Amended and  Restated
Articles of  Incorporation.  In tabulating  the votes on the proposal to approve
the adoption of the Amended and Restated Articles of Incorporation,  abstentions
and broker non-votes will have the same effect as a negative vote.

            A  plurality  of the votes  cast is  required  for the  election  of
directors. In tabulating the vote on the election of directors,  abstentions and
broker "non-votes" will be disregarded and will have no effect on the outcome of
such vote.

            The affirmative  vote of a majority of the votes cast is required to
approve  the  adoption  of the  Option  Plans and the  proposal  to  ratify  the
appointment  of Ernst & Young LLP. In  tabulating  the votes on the proposals to
approve the adoption of the Option Plans and ratify the  appointment  of Ernst &
Young LLP,  abstentions and broker non-votes are not considered  shares entitled
to vote on the applicable  proposals and are not included in determining whether
the adoption of the Option Plans and the proposal to ratify the  appointment  of
Ernst & Young LLP are approved.

                               ATTENDING IN PERSON

            Only  stockholders,  their proxy holders,  and the Company's invited
guests may attend the Annual  Meeting.  If a person  wishes to attend the Annual
Meeting, but holds his shares through someone else, such as a broker, the person
must bring proof of his ownership and identification  with a photo to the Annual
Meeting.  For example,  the person could bring an account statement showing that
he owned shares of Common Stock or Exchangeable  Shares as of the Record Date as
acceptable proof of ownership.

                                       3

<PAGE>

         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

            The  following  table  contains  information  as of the Record  Date
regarding  the  beneficial  ownership of shares of Common Stock by the Company's
current directors and executive officers,  nominees for director,  those persons
or entities who, to the Company's  knowledge,  beneficially  own more than 5% of
the Common Stock and by all directors and executive officers as a group.  Unless
otherwise  indicated,  each  stockholder  has sole voting power and  dispositive
power with respect to the indicated shares:

<TABLE>
<CAPTION>

                                                 Shares of Common                  Percentage of Common
                 Name and Address of            Stock Beneficially                  Stock Beneficially
                   Beneficial Owner                Owned (1)(2)                            Owned

<S>                                                     <C>                                 <C>
9083-1496 Quebec Inc. (3)                               7,640,000                           26.2%
475 Boulevard Armand-Frappier
Laval, Quebec, Canada
H7V 4B3

Amine Selmani (3)                                       7,977,500(4)                        27.0%
475 Boulevard Armand-Frappier
Laval, Quebec, Canada
H7V 4B3

Marie Claire Pilon                                              0                           --

Denis N. Beaudry (5)                                       25,000(6)                        (7)

Pierre Alary                                               25,000(6)                        (7)

Jean-Yves Bourgeois                                        25,000(6)                        (7)

Pierre Ranger                                             125,000(8)                        (7)

Anthony Casola                                                  0                           --

All Officers and Directors                              8,177,500(9)                        27.5%
as a group (7 persons)
</TABLE>

-------------------


(1)      Includes  rights to acquire shares of Common Stock through the exchange
         of Exchangeable Shares.

(2)      A person is deemed to be the beneficial owner of voting securities that
         can be  acquired  by such  person  within 60 days after the Record Date
         upon the exercise or  conversion  of options,  warrants or  convertible
         securities.  Each beneficial owner's percentage ownership is determined
         by assuming that options,  warrants and convertible securities that are
         held by such person  (but not those held by any other  person) and that
         are  exercisable  or  convertible  within 60 days after the Record Date
         have been exercised or converted.

(3)      Dr.  Selmani does not own directly  any  Exchangeable  Shares or Common
         Stock.  However,  by virtue of his ownership of 9083-1496  Quebec Inc.,
         Dr. Selmani has shared voting and dispositive power with respect to the
         7,640,000  Exchangeable  Shares  owned by  9083-1496  Quebec  Inc.  Dr.
         Selmani also may be deemed the  beneficial  owner of 337,500  shares of
         Common  Stock  that  would be held by him upon  exercise  of options to
         purchase  25,000  shares of Common Stock  granted under the BSYI Option
         Plan and exchange of 312,500 Exchangeable Shares issuable upon exercise
         of options granted to Dr. Selmani under the BSC Option Plan.

                                       4

<PAGE>

(4)      Does not  include an  aggregate  of  1,085,000  shares of Common  Stock
         (which  includes  200,000 shares  issuable upon the exercise of options
         granted under the BSC Option Plan) beneficially owned by Monique Jarry,
         the spouse of Dr.  Selmani.  Ms.  Jarry is deemed to be the  beneficial
         owner of such  shares  of  Common  Stock by  reason  of her  beneficial
         ownership  of the same  number  of  Exchangeable  Shares.  Dr.  Selmani
         disclaims beneficial ownership of such shares.

(5)      Denis N. Beaudry is the representative of Polyvalor, Inc. ("Polyvalor")
         on the Company's Board of Directors.  The shares reflected in the table
         above do not include 1,072,000  Exchangeable  Shares beneficially owned
         by Polyvalor,  which are exchangeable on a one-for-one basis for shares
         of  Common  Stock,  as  to  which  Mr.  Beaudry  disclaims   beneficial
         ownership.  Please see "Certain Relationships and Related Transactions"
         for a description of the agreements  under which  Polyvalor is entitled
         to designate a member of the Company's Board of Directors.

(6)      Represents  25,000  shares of Common Stock  issuable  upon  exercise of
         options granted to such Directors under the BSYI Option Plan.

(7)      Less than 1.0%.

(8)      Represents  (i) 25,000 shares of Common Stock issuable upon exercise of
         options  granted under the BSYI Option Plan and (ii) 100,000  shares of
         Common  Stock  that  would be  beneficially  owned by Dr.  Ranger  upon
         exchange  of 100,000  Exchangeable  Shares  issuable  upon  exercise of
         options granted to Dr. Ranger under the BSC Option Plan.

(9)      Includes an aggregate of 125,000  shares of Common Stock  issuable upon
         exercise  of options  granted  under the BSYI  Option  Plan and 412,500
         shares of Common Stock  issuable upon exchange of 412,500  Exchangeable
         Shares  issuable upon exercise of options  granted under the BSC Option
         Plan.


                                       5


<PAGE>


                                 PROPOSAL NO. 1

                 APPROVING ADOPTION OF THE AMENDED AND RESTATED
                    ARTICLES OF INCORPORATION OF THE COMPANY

            The Board of  Directors  recommends  the approval of the adoption of
proposed Amended and Restated Articles of Incorporation.  The Board of Directors
believes Amended and Restated  Articles of Incorporation  are required to ensure
that the Company's Articles of Incorporation  conform to the requirements of the
General Corporation Law of the State of Nevada. In approving this proposal,  the
stockholders  will also be (i)  ratifying  a change in the  Company's  name from
"Dream Team  International,  Inc." to  "BioSyntech,  Inc.";  (ii)  approving  an
increase from 50,000,000 to [100,000,000] in the Company's  authorized shares of
Common Stock and the creation a new class of Preferred Stock  consisting of five
million  (5,000,000)  shares, par value $.001 per share (the "Preferred Stock");
(iii) approving the classification of the Board of Directors and (iv) confirming
the elimination of preemptive  rights.  The amended  provisions  relating to the
Company's  capital structure will also remove references to any prior actions by
the Company relating to its capital structure.

            The following  describes the  ratification  of the name change,  the
proposed changes in the Company's capital  structure,  the classification of the
Board of Directors and the confirmation of elimination of preemptive rights. The
Amended and Restated  Articles of  Incorporation  are attached hereto as Annex I
and this  discussion of the Amended and Restated  Articles of  Incorporation  is
qualified in its entirety by reference to Annex I.

Change in Corporate Name

            Prior  to  February   2000,   the  Company  was  a   publicly-traded
corporation  without  operations  known  as  "Dream  Team  International,  Inc."
Pursuant to an Amalgamation  Agreement and related  agreements,  as amended (the
"Exchange  Agreements"),  dated February 15, 2000 by and among the Company,  its
then  wholly-owned  subsidiary  9083-5661  Quebec  Inc.,  a  Quebec  corporation
("9083-5661"),  Bio Syntech Ltd., a Quebec corporation,  and the shareholders of
Bio Syntech (the "Bio Syntech  Shareholders"),  on February 29, 2000,  9083-5661
and Bio Syntech Ltd. became a subsidiary of the Company.  In connection with the
Exchange Agreements, the Company sought to change its name to "BioSyntech, Inc."
so that the  Company's  name  would be  aligned  with  its  operating  business.
Ratification  of the name change is necessary  because while the name change was
purportedly  approved on December 28, 1999 by written  consent of the holders of
the majority of the then  outstanding  shares of Common Stock,  certain required
formalities of law were not observed. In addition to ensuring that the Company's
name would be aligned with its operating business,  the ratification of the name
change would  eliminate  potential  confusion  over the identity of the Company,
because it has been doing  business and has filed reports with the United States
Securities  and  Exchange  Commission  (the "SEC") as  "BioSyntech,  Inc." since
February 29, 2000.

            There will be no consequences to stockholders  from the ratification
of the name  change.  If this  proposal  is  adopted,  stockholders  will not be
required to exchange outstanding stock certificates for new certificates.

Increase in Authorized Capital

            The Company is currently  authorized to issue  50,000,000  shares of
Common  Stock.  As of the Record  Date,  29,182,250  shares of Common Stock were
issued and outstanding (including 15,177,036 Trust Shares),  4,000,000 shares of
Common Stock that are reserved for issuance upon the exercise of

                                       6

<PAGE>

options granted or to be granted under the Option Plans and 2,380,214  shares of
Common Stock that are reserved for issuance upon  exercise of warrants.  If this
Proposal  No. 1 is approved,  the  Company's  authorized  shares of Common Stock
would increase from fifty million  (50,000,000)  shares to [one hundred  million
(100,000,000)] shares and five million  (5,000,000)  shares of  Preferred  Stock
would be authorized.

            The Company anticipates that it will seek to raise additional equity
capital over the next several  years.  These efforts may include both public and
private  offerings of Common Stock, as well as other securities  exercisable for
or  convertible  into  Common  Stock.  The Company  currently  does not have any
specific  plans,  understandings  or  agreements  for the issuance or use of the
proposed  additional  shares of Common  Stock or Preferred  Stock.  The Board of
Directors  believes  that if an increase in the  authorized  number of shares of
Common Stock and the authorization of Preferred Stock were to be postponed until
a specific need arose,  the delay and expense incident to obtaining the approval
of the  Company's  stockholders  at that time  could  significantly  impair  the
Company's ability to meet its financing objectives.

            The Board of Directors  believes the proposed increase in the number
of  authorized  shares of Common  Stock is necessary to provide the Company with
the  flexibility  to act in the  future  with  respect  to  financing  programs,
acquisitions,  mergers,  stock  splits,  convertible  debt  financing,  employee
benefit plans and other corporate purposes. If the proposed Amended and Restated
Articles of Incorporation become effective,  the Board of Directors will be free
to issue the additional authorized shares of Common Stock without further action
on  the  part  of  stockholders  (except  as may be  required  for a  particular
transaction by applicable law,  requirements of regulatory  agencies or by stock
exchange or automated  quotation system rules).  The additional shares of Common
Stock to be authorized will have rights  identical to the shares of Common Stock
currently outstanding.

            The  Board of  Directors  also  believes  the  complexity  of modern
business financing and possible future transactions  require greater flexibility
in the Company's capital structure than currently exists. Should Preferred Stock
be issued,  the powers,  preferences  and  rights,  such as dividend or interest
rates,  conversion prices, voting rights,  redemption prices, maturity dates and
similar matters, would be determined by the Board of Directors,  without further
authorization of the  stockholders.  If this proposal is approved,  the Board of
Directors  would be permitted to issue Preferred Stock from time to time for any
proper corporate purpose.  Shares of Preferred Stock could be issued publicly or
privately,  in one or more series, and each series of Preferred Stock would rank
senior to the Common Stock with respect to dividend  and/or  liquidation  rights
and could have greater voting power than the Common Stock.

            The  authorization of additional  shares of Common Stock pursuant to
this proposal will itself have no dilutive effect upon the proportionate  voting
power of the present  stockholders of the Company.  However,  to the extent that
the Company  subsequently  issues shares of Common Stock and Preferred  Stock to
persons  other  than  the  present  stockholders,  the  issuance  could  have  a
substantial dilutive effect on present stockholders.  The issuance of additional
shares of Common Stock and Preferred  Stock may also have the effect of diluting
the stock  ownership  of  persons  seeking  to obtain  control  of the  Company.
Although  the Board of  Directors  has no  present  intention  of doing so,  the
Company's  authorized  but unissued  Common Stock and  Preferred  Stock could be
issued in one or more  transactions that would make it more difficult or costly,
and less likely, to take control of the Company.  The proposed  amendment to the
Company's  Articles of Incorporation is not being recommended in response to any
specific  effort to obtain control of the Company of which the Company is aware.
No stockholder of the Company will have any preemptive  rights  regarding future
issuance of any shares of Common Stock or Preferred Stock.

                                       7

<PAGE>

Classified Board of Directors

            If this  Proposal  No. 1 is  approved,  the  Company's  Articles  of
Incorporation  and Bylaws would provide for staggered  terms of the directors of
the Company,  effective  immediately and affecting the directors  elected at the
Annual Meeting.

            Under the  proposal,  the Board of  Directors  would be divided into
three classes with each Class 1 director  elected to serve until the 2001 annual
meeting of  stockholders,  each Class 2 director elected to serve until the 2002
annual meeting of stockholders, and each Class 3 director elected to serve until
the 2003 annual meeting of stockholders.  At each annual meeting of stockholders
following this Annual  Meeting,  the number of directors  equal to the number of
directors in a class whose term expires at the time of such annual meeting would
be elected to serve until the third  succeeding  annual meeting of stockholders.
Notwithstanding the foregoing,  directors would serve until their successors are
elected and qualified or until their death,  resignation or removal from office.
Vacancies that occur during the year would be filled by the majority vote of the
remaining  members of the Board of Directors then in office,  and each person so
elected would serve the remainder of the full term of the class to which the new
director was elected.

            The Board of Directors  believes that the staggered  three-year term
of a  classified  board,  with its  election of  approximately  one-third of the
directors  each year,  will help  assure the  continuity  and  stability  of the
Company's long-term policies in the future, since a majority of the directors at
any given  time will have prior  experience  as  directors  of the  Company.  In
addition,  the Board of Directors  believes  that the proposed  amendments  will
permit it to represent more  effectively the interests of all  stockholders in a
variety  of  situations,  including  dealing  with  proposals  or  actions  by a
disruptive  substantial  stockholder  or stockholder  group.  The Company is not
currently aware of any such proposals or actions.

            A  classified  board  will  also  have an  effect  of making it more
difficult to replace incumbent directors and management,  even if the reason for
the desired change is inadequate performance.  So long as the Board of Directors
is  classified  into  three  classes,  a minimum  of three  annual  meetings  of
stockholders  would  generally  be  required  to  replace  the  entire  Board of
Directors, absent intervening vacancies. While the proposal is not intended as a
takeover-resistive  measure in response to a specific threat,  it may discourage
the  acquisition  of large blocks of the Company's  shares by causing it to take
longer  for a person  or group of person  who  acquire  such  block of shares to
effect a change in management.

Confirmation of Elimination of Preemptive Rights

            If  this  Proposal  No.  1  is  approved,   preemptive   rights  for
stockholders  of the Company will be eliminated in their  entirety.  The Company
believes that future  offerings of its equity  securities will be more effective
if there is no question as to whether its stockholders have preemptive rights If
stockholders do have preemptive rights, the Company may not in general cause the
issuance of authorized  shares of Common Stock without first offering  shares to
existing stockholders on the same terms as the proposed new offering.  The Board
of  Directors   believes  that  this  requirement   could  limit  the  Company's
flexibility and adversely affect the price and expense of future financings. The
General   Corporation  Law  of  the  State  of  Nevada  provides  that  existing
stockholders  have  no  preemptive  rights  unless  the  preemptive  rights  are
explicitly  provided  for  in  the  Company's  Articles  of  Incorporation.  The
Company's  Articles of  Incorporation  currently  provide for preemptive  rights
subject  to  certain  restrictions.  Based  on  a  review  of  the  Articles  of
Incorporation  and the  General  Corporation  Law of the  State of  Nevada,  the
Company believes that such restrictions include eliminating preemptive rights if
the  Company's  Common Stock is registered  under  Section 12 of the  Securities
Exchange  Act of 1934,  as amended (the  "Exchange  Act").  In August 1999,  the
Company's  Common Stock was registered under Section 12 of the Exchange

                                       8

<PAGE>

Act. The Company also believes that the original intent and understanding of the
initial stockholders of the Company was for them to have preemptive rights while
the Company was privately held and that once the Company  became  publicly held,
such preemptive rights would be eliminated.  To ensure the explicit  elimination
of preemptive  rights under the General  Corporation Law of the State of Nevada,
however, this Proposal No. 1 would delete all references to preemptive rights in
the Articles of Incorporation.  Accordingly,  if this Proposal No.1 is approved,
the  stockholders  of the  Company  would have no  preemptive  rights  under any
circumstances.

Required Vote

            The  affirmative  vote of a majority  of the  outstanding  shares of
Common  Stock is  required  to approve  the  proposal  to amend and  restate the
Company's Articles of Incorporation.

                 THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR"
           APPROVAL OF THE PROPOSAL TO ADOPT THE AMENDED AND RESTATED
                    ARTICLES OF INCORPORATION OF THE COMPANY


                                   PROPOSAL 2

                       ELECTION OF THE BOARD OF DIRECTORS

            Unless  otherwise  specified,  all Proxies received will be voted in
favor of the election of the persons named below as directors of the Company. If
Proposal No. 1 is approved,  the directors  would be divided into three classes.
At the Annual Meeting,  two Class 1 Directors would be elected,  each to serve a
one-year  term until the 2001  Annual  Meeting of  Stockholders  and until their
successors are elected and qualified. The nominees for Class 1 Directors are Ms.
Marie-Claire  Pilon and Mr. Pierre  Alary.  At the Annual  Meeting,  two Class 2
Directors would be elected,  each to serve a two-year term until the 2002 Annual
Meeting of  Stockholders  and until their  successors are elected and qualified.
The nominees for Class 2 Directors  are Mr.  Jean-Yves  Bourgeois and Dr. Pierre
Ranger. At the Annual Meeting,  two Class 3 Directors would be elected,  each to
serve a three-year term until the 2003 Annual Meeting of Stockholders  and until
their  successors are elected and qualified.  The nominees for Class 3 Directors
are Dr. Amine  Selmani and Mr. Denis N. Beaudry.  Following the Annual  Meeting,
one class of directors would be elected each year, and the members of such class
would hold  office for a  three-year  term and until their  successors  are duly
elected and qualified, or until their death, resignation or removal from office.
If Proposal No. 1 is not  approved,  then six  directors  will be elected at the
Annual  Meeting each to serve for a one-year term until the 2001 Annual  Meeting
of Stockholders and until their successors are elected and qualified.

            Each of the  nominees,  other  than  Marie-Claire  Pilon,  has  been
serving as a director of the Company since February 2000. The terms of office of
the current directors expire at the Annual Meeting and when their successors are
duly  elected and qualify.  Management  has no reason to believe that any of the
nominees' will be unable or unwilling to serve as a director, if elected. Should
any of the  nominees  not remain a  candidate  for  election  at the date of the
Annual Meeting,  the Proxies will be voted in favor of those nominees who remain
candidates  and may be voted for  substitute  nominees  selected by the Board of
Directors. The names of the nominees and certain information concerning them are
set forth below:

                                       9

<PAGE>

                  Nominee(1)                Proposed Class            Age
                  ----------                --------------            ---

         Amine Selmani                         Class 3                 43

         Marie-Claire Pilon                    Class 1                 46

         Denis N. Beaudry                      Class 3                 57

         Pierre Alary                          Class 1                 43

         Jean-Yves Bourgeois                   Class 2                 33

         Pierre Ranger                         Class 2                 45

--------------------

(1)  Mr. Beaudry is the nominee of Polyvalor  which has the right to appoint one
nominee  to the Board of  Directors.  See  "Certain  Relationships  and  Related
Transaction - Agreement with Polyvalor." There are no family relationships among
the directors and executive officers of the Company.

            Amine Selmani Ph.D.- Dr. Selmani has served as Chairman of the Board
and President of the Company since February 2000, Chief Executive Officer of the
Company  from  February  2000 to  September  2000  and  Chairman  of the  Board,
President and Chief Executive  Officer of Bio Syntech Canada and its predecessor
corporation  since  its  inception  in  November  1997.  Prior to  founding  the
predecessor corporation of Bio Syntech Canada in May 1995, Dr. Selmani had eight
years  of  teaching  experience  at  the  Chemical  Engineering  Department  and
Biomedical  Institute of Ecole Polytechnique as an Associate Professor from 1992
to 1997 and as an Assistant  Professor from 1989 to 1992.  Dr. Selmani  received
his Bachelor of Science and Master of Science  Degrees in Physical  Chemistry in
1979 and 1981,  respectively,  from the University of Bordeaux,  France. He also
obtained his Doctoral and Post  Doctoral  Degrees in Materials  Science from the
University of Montreal in 1985 and Dalhousy University in 1988, respectively.

            Marie-Claire Pilon - Ms. Pilon became the Chief Executive Officer of
the Company in September  2000.  Ms Pilon is a pharmacist  and hold an Executive
Masters  in  Business   Administration   from  the   University  of  New  Haven,
Connecticut.  Prior to  joining  the  Company,  Ms Pilon held a number of senior
positions within both the North American and European  pharmaceutical  industry.
Most recently, Ms. Pilon was a Senior Business Development Consultant to private
and publicly traded companies. In that role, she assumed the responsibilities of
Executive  Vice  President of Business  Development  for Nastech  Pharmaceutical
Company, Inc., a publicly traded nasal drug delivery company. From 1996 to 1999,
Ms.  Pilon was  Vice-President  of  Biovail  Corporation  International,  a full
service  pharmaceutical  company  engaged  in  the  formulation,   registration,
clinical  testing and  manufacture  of drug  products  utilizing  advanced  drug
delivery  technologies.  From 1994 to 1995, Ms. Pilon was Executive Director for
Business  Development  for the  Benefit  Research  Group,  a  Quintiles  company
specializing in Health Economics and Outcomes  Research.  From 1981 to 1994, Ms.
Pilon held positions of increasing responsibilities within the industry.

            Denis N.  Beaudry - Mr.  Beaudry  has been a director of the Company
since  February  2000.  Mr.  Beaudry has been  President and general  manager of
Polyvalor,  Montreal,  Quebec, Canada, a limited partnership formed by the Ecole
Polytechnique for the purpose of  commercializing  the intellectual  property of
the Ecole  Polytechnique.  His role  consists of enhancing the value of research
results for commercial use by means of start-up of high-tech  companies in which
Polyvalor  holds a  participation  or interest.  Since 1984, he has occupied the
position of director of the Centre de  Developpement

                                       10

<PAGE>

Technologique  of the Ecole  Polytechnique  whose sphere of activities  includes
technology transfer,  licensing of technology and software,  joint creation with
private  industry of laboratories  and research  centers,  strategic  alliances,
research  partnerships,  industrial  chairs and the emergence of high technology
enterprises.  Mr. Beaudry was President of the Quebec  Association of University
Research Directors in 1992, and is at present a member of the Board of Directors
of the Centre des Technologies  Textiles,  the College Rosemont, the Corporation
de  Financement  de  l'Institut  de  Cardiologie  de  Montreal,  the  Centre  de
Technologies  du  Gaz  Naturel,   the   Corporation   Commerciale  de  Materiaux
Composites,  the Centre de Developpement Rapide de Produits et de Procedes,  and
of the firms  Lumenon  Innovative  Lightwave  Technologies,  Inc.,  Sinlab Inc.,
Phytobiotech Inc., Polyplan Inc., Odotech Inc. and COESI Inc.

            Pierre  Alary,  CA - Mr.  Alary has been a director  of the  Company
since February 2000.  Since August 1998, Mr. Alary has been a Vice President for
finance  and  information  technologies  at  Bombardier  Transport,  a designer,
manufacturer  and  distributor  of  rail  cars.  Prior  to  joining   Bombardier
Transport,  Mr. Alary has held various  positions  from September 1978 to August
1998,  including as Senior  Partner,  at Ernst & Young LLP,  specializing in the
biotechnology industry.

            Jean-Yves  Bourgeois  - Mr.  Bourgeois  has been a  director  of the
Company since February 2000.  Since 1999, Mr.  Bourgeois has been a director and
Senior Vice  President  in charge of  corporate  finance  for Eastern  Canada of
Canaccord, a securities broker/dealer. Prior to joining Canaccord, Mr. Bourgeois
served as a Chief Financial Officer for Aeterna  Laboratories from 1998 to 1999.
From 1997 to 1998, Mr. Bourgeois had also been in charge of small capital market
development,  specializing in high technology and biotechnology industries,  for
TD Securities, a securities broker/dealer. From 1992 to 1997, Mr. Bourgeois held
various  positions,  including the head of corporate finance for eastern Canada,
at Gordon  Capital,  a securities  broker/dealer,  where he  specialized in high
technology and biotechnology industries.

            Pierre  Ranger MD - Dr.  Ranger has been a director  of the  Company
since February 2000. Since 1991, Dr. Ranger has been a teaching professor in the
orthopedic residents program at the CMDP Sacred Heart Hospital of Montreal.  Dr.
Ranger  received his Medical  Degree from the University of Montreal in 1979 and
Diploma of Sports Medicine in 1996.

Committees of the Board of Directors

            The Board of Directors has formed a  Compensation  Committee,  which
administers the Option Plans and makes  recommendations  concerning salaries and
incentive  compensation for employees of and consultants to the Company,  and an
Audit Committee, which reviews the Company's financial statements and accounting
policies,  resolves  potential  conflicts of interest,  receives and reviews the
recommendations  of the  Company's  independent  auditors  and confers  with the
Company's  independent  auditors with respect to the training and supervision of
internal accounting  personnel and the adequacy of internal accounting controls.
The Compensation  Committee is currently  composed of Mr. Bourgeois  (Chairman),
Mr. Alary and Dr.  Ranger and the Audit  Committee is currently  composed of Mr.
Alary (Chairman), Mr. Beaudry and Mr. Bourgeois.

            The Company  presently  does not have a  nominating  committee,  the
customary  functions of such  committee  being  performed by the entire Board of
Directors.

Meetings

            The Board of  Directors  held [one]  meeting  during the fiscal year
ended March 31, 2000. The  Compensation  Committee and the Audit  Committee each
held [one]  meeting  during the fiscal year ended March 31, 2000.  All directors
were  present at each  meeting of the Board of  Directors  and each meeting

                                       11

<PAGE>

of a Committee in which they  members of. From time to time,  the members of the
Board of Directors  act by  unanimous  written  consent  pursuant to the General
Corporation Law of the State of Nevada.

Other Executive Officers

            Anthony Casola - Mr. Casola has been the Chief Financial Officer and
Secretary of the Company since  September  2000.  From August 1990 to June 2000,
Mr. Casola worked for Naya Inc., a branded bottled water manufacturer,  where he
held various  senior  positions in the accounting and finance areas such as Vice
President  for  Corporate  Development,  Director  of  Finance,  Controller  and
Accounting  Manager.  Mr. Casola  obtained his Bachelor of Commerce  degree from
McGill  University  in June 1986.  He has also been  designated  as a  Certified
Management Accountant since January 1989.

Board of Directors Compensation

            The Board of Directors does not currently  compensate  directors for
their service on the Board of  Directors.  Directors  are  reimbursed  for their
expenses  incurred in attending  meetings of the Board of  Directors.  Under the
terms of the BSYI Option Plan, directors are eligible for the grant of options.

            The Board of Directors will determine the  remuneration of directors
during the current and  subsequent  fiscal  years.  In August  2000,  options to
purchase 50,000 shares of Common Stock at an exercise price of US$4.00 per share
was granted to each of Messrs.  Selmani,  Beaudry,  Alary,  Bourgeois and Ranger
under the BSYI Option Plan. In August 2000,  options to purchase  175,000 shares
of Common  Stock at an  exercise  price of US$4.00  per share was granted to Ms.
Pilon under the BSYI Option Plan.

                 THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR"
                      THE ELECTION OF EACH OF THE NOMINEES


                             EXECUTIVE COMPENSATION

Compensation of Executives

            The  following  table sets  forth,  for the periods  indicated,  all
compensation awarded to, earned by or paid to the Chief Executive Officer of Bio
Syntech Ltd., which was merged with the Company's wholly-owned  subsidiary,  Bio
Syntech Canada,  effective  February 29, 2000. Except for those listed below, no
other  executive  officers of the Company and Bio Syntech Ltd.  received  annual
compensation  in  excess  of US  $100,000  during  the  periods  indicated.  The
Company's  functional  currency is the Canadian dollar. All amounts presented in
this Proxy Statement in U.S.  currency are identified as such. Other amounts are
expressed in Canadian dollars.

                                       12

<PAGE>

Summary Compensation Table
<TABLE>
<CAPTION>

                                                                                      Long-Term Compensation:
                                                      Annual Compensation(1)                  (Awards)
                                                      ----------------------
                                                                                            Securities
        Name and Position      Fiscal Year          Salary                  Bonus     Underlying Options (#)
        -----------------      ------------         ------                  -----     ----------------------
<S>                               <C>             <C>                        <C>           <C>
Amine Selmani                     2000            $120,000                   $0                 -
President and Chief               1999            $120,000                   $0            312,500(2)
Executive Officer                 1998            $0                         $0                 -
</TABLE>

----------------
(1)      Certain of the  executive  officers  of the Company  routinely  receive
other  benefits  from the  Company,  the amounts of which are  customary  in the
Company's industry.  The Company has concluded,  after reasonable inquiry,  that
the aggregate  amounts of such benefits during each of the periods  reflected in
the  table  above  did  not  exceed  the  lesser  of  US$50,000  or  10%  of the
compensation  set forth  above for any named  individual  in respect of any such
period.

(2)      Represents  options to purchase  Exchangeable  Shares awarded under the
BSC Option Plan.

Option Grants

         No options were  granted to Dr.  Selmani in the fiscal year ended March
31, 2000. The Company has never granted any stock appreciation rights.

Aggregated Fiscal Year-End Option Exercises and Option Values

         Dr.  Selmani did not exercise any options  during the past fiscal year.
The following table sets forth certain information  regarding  unexercised stock
options held by Dr. Selmani as of March 31, 2000.

<TABLE>
<CAPTION>

                                    Number of Securities Underlying       Value of Unexercised In-The-
                                      Unexercised Options at                    Money Options at
                                       March 31, 2000(#)                        March 31, 2000($)
         Name                         Exercisable/Unexercisable           Exercisable/Unexercisable(1)
         ----                         -------------------------           ----------------------------
<S>                                           <C>     <C>                         <C>        <C>
Amine Selmani                                 312,500/0                           $1,596,094/0
</TABLE>

-----------------

(1) Based on the market  value,  as reported on the Over the Counter  Electronic
Bulletin  Board, of US$5.6250 per share of Common Stock at March 31, 2000 and an
exercise price of $0.75 (US$0.5175) per share.

Other Compensation Plans

            The Company has no pension plan or other  compensation plans for its
executive officers or directors.


                                       13

<PAGE>

Employment Agreement

            Marie-Claire Pilon Employment Agreement

            The Company has entered into a three-year  employment agreement with
Marie-Claire  Pilon dated as of August 7, 2000.  Since September 2000, Ms. Pilon
has served as Chief Executive Officer with such duties and  responsibilities  as
are  determined by the Board of Directors  from time to time. Ms. Pilon receives
an annual base salary of  $165,000,  which is to be  reviewed  annually,  plus a
bonus payment at the discretion of the Compensation Committee.  The Company also
granted Ms.  Pilon  options to  purchase  175,000  shares of Common  Stock at an
exercise  price of $4.00 per  share,  vesting in three  installments  commencing
August 2001. Throughout the term of her employment and for a period of two years
thereafter,  the agreement restricts Ms. Pilon's ability to engage in activities
competitive  with  those of the  Company.  Additionally,  during  the same  time
period,  Ms.  Pilon has agreed that she will not solicit any person  employed by
the Company to leave its employ,  or employ or solicit for employment any person
who is employed by the Company.  If Ms. Pilon's  employment is terminated by the
Company without cause, she is entitled to receive her base salary for six months
or for 12 months, depending upon the date of termination.  Ms. Pilon will not be
entitled to receive any salary if she is  terminated  for cause,  disability  or
death.

            Anthony Casola Employment Agreement

            The Company has entered into a three-year  employment agreement with
Anthony Casola dated as of September 2000.  Since September 2000, Mr. Casola has
served  as  Chief   Financial   Officer  and  Secretary  with  such  duties  and
responsibilities  as  are  determined  by  the  Company's  Board  of  Directors,
President or Chief  Executive  Officer from time to time. Mr. Casola receives an
annual base salary of $125,000,  which is to be reviewed annually,  plus a bonus
payment at the  discretion  of the  Compensation  Committee.  The  Company  also
granted Mr.  Casola  options to  purchase  50,000  shares of Common  Stock at an
exercise  price of $4.00 per  share,  vesting in three  installments  commencing
September  2001.  Throughout  the term of his employment and for a period of two
years  thereafter,  the agreement  restricts Mr.  Casola's  ability to engage in
activities competitive with those of the Company. Additionally,  during the same
time period,  Mr. Casola has agreed that he will not solicit any person employed
by the Company to leave its  employ,  or employ or solicit  for  employment  any
person who is employed by the Company.  If Mr. Casola's employment is terminated
by the Company without cause, he is entitled to receive his base salary for four
months or for 12 months, depending upon the date of termination. Mr. Casola will
not be entitled to receive any salary if he is terminated for cause,  disability
or death.

                                       14

<PAGE>

Section 16(a) Beneficial Ownership Reporting Compliance

            Section 16(a) of the Exchange Act as amended, requires the Company's
directors and executive officers, and persons who beneficially own more than ten
percent of the Company's Common Stock, to file with the SEC reports of ownership
of Common Stock and other equity securities of the Company. Officers,  directors
and more than ten percent stockholders are required by SEC regulation to furnish
the Company with copies of all Section 16(a) reports they file. To the Company's
knowledge, based solely on review of the copies of such reports furnished to the
Company during the fiscal year ended March 31, 2000, all required  Section 16(a)
filings by beneficial owners were complied with.

Certain Relationships And Related Transactions

            Exchange Agreements

            As a result of the  Exchange  Agreements,  the  Company  became  the
record and beneficial  owner of all of the issued and outstanding  shares of Bio
Syntech  Canada's  Common  Stock and the Bio  Syntech  Shareholders  were issued
Exchangeable   Shares.   The   Exchangeable   Shares  are   exchangeable   on  a
share-for-share  basis for an aggregate of  15,177,036  shares of Common  Stock,
which were issued in  accordance  with the Exchange  Agreements  and are held in
trust  under  the  terms  of  an  Exchange  and  Voting  Agreement  (the  "Trust
Agreement"),  by and among the  Company,  Pierre  Barnard (the  "Trustee"),  Bio
Syntech  Ltd.  and  9083-5661.  (The  foregoing  transactions  are  referred  to
collectively hereinafter as the "Transactions"). Bio Syntech Ltd. was founded in
1995 by Dr. Amine Selmani,  the Company's  Chairman of the Board,  President and
the  beneficial  holder of more than 5% of the  outstanding  Common  Stock.  Dr.
Selmani  has shared  voting and  dispositive  power  with  respect to  7,640,000
Exchangeable  Shares  owned  by  9083-1496  Quebec  Inc.  as  a  result  of  the
Transactions.

            Under the terms of the Trust  Agreement,  each beneficial  holder of
Exchangeable  Shares has voting  rights in that number of Trust  Shares equal in
number to the number of Exchangeable Shares held. Consequently,  the Bio Syntech
Shareholders  held through the Trustee,  securities  with voting rights equal to
approximately  55.7% (currently  approximately 52%) of the total voting power of
the outstanding Common Stock immediately after the Transactions. At such time as
the holders of  Exchangeable  Shares may exchange  such shares for Common Stock,
they will have the right to direct the  disposition of such Common Stock.  Under
the terms of the Trust  Agreement,  the Trustee  will abstain from voting any of
the Trust Shares as to which he does not receive  voting  instructions  from the
holders of Exchangeable Shares.

            The sole  source of  consideration  for  issuance to the Bio Syntech
Shareholders of the Exchangeable Shares was the exchange of the Bio Syntech Ltd.
shares held by them. At such time as the Bio Syntech  Shareholders  may exchange
their Exchangeable Shares for Common Stock, the sole source of consideration for
the transfer to them of the Common Stock will be such Exchangeable Shares.

            The Exchange  Agreements  were structured to provide the Bio Syntech
Shareholders  with a capital gain deferral under  applicable  Canadian tax laws,
rules and regulations.

            Agreement with Polyvalor

            In October 1997,  the Company  entered into a technology  assignment
agreement,  as amended in September  1999 and as amended and restated  March 15,
2000  (the  "Assignment  Agreement"),  with  Polyvalor  Limited  Partnership,  a
Canadian limited partnership,  as represented by its General Partner, Polyvalor.
Polyvalor  is  an  entity  created  by  Ecole  Polytechnique  de  Montreal  (the
University of Montreal's  engineering  faculty,  "Ecole  Polytechnique") for the
purpose of  commercializing  the technology in which Ecole  Polytechnique has an
interest.  Through the Assignment Agreement, the

                                       15


<PAGE>

Company  acquired  from  Polyvalor  all rights  related to certain  patents  and
know-how.  In  consideration  of said  assignment,  the Company agreed to pay to
Polyvalor a royalty of 5% on all gross sales of all products  and services  sold
by  the  Company,  up to a  maximum  cumulative  amount  of CDN  $3,000,000.  In
connection with the Assignment  Agreement,  the Company's subsidiary Bio Syntech
Canada,  issued to Polyvalor  1,072,000  shares of its  Exchangeable  Shares and
granted  Polyvalor the right to nominate one director to the Company's  Board of
Directors.  As a  result  of  the  Transactions,  the  Exchangeable  Shares  are
exchangeable on a share for share basis for Common Stock,  and Polyvalor has the
right to nominate one director to the Company's Board of Directors.



                                   PROPOSAL 3

             ADOPTION OF STOCK OPTION INCENTIVE PLANs OF THE COMPANY
                             AND BIO SYNTECH CANADA

            The Board of Directors has unanimously  approved for submission to a
vote of the  stockholders a proposal to approve the Option Plans as set forth in
Annex II and Annex III, respectively,  to this Proxy Statement.  This discussion
is  qualified  by its  entirety by  reference to Annex II and Annex III. As used
herein with respect to the Option Plans,  references to the Company  include Bio
Syntech Canada and other subsidiaries of the Company, where appropriate.

            The  purposes  of the  Option  Plans are to enable  the  Company  to
attract and retain  persons of ability as directors,  officers and key employees
with managerial,  professional or supervisory  responsibilities,  to retain able
consultants and advisors, and to motivate such persons to use their best efforts
on behalf of the Company, by providing them with an equity  participation in the
Company.

            The Board of Directors  believes that it is in the of best interests
of the Company and its  stockholders  to approve  the Option  Plans  because the
Option Plans provide the Company with greater  ability to attract and retain key
personnel.

The Option Plan

            The Participants

            Options to purchases  shares  Common Stock and  Exchangeable  Shares
(the  "Options") may be granted to (i) directors,  officers and other  full-time
salaried  employees of the Company with managerial,  professional or supervisory
responsibilities,  and (ii)  consultants  and  advisors  who  render  bona  fide
services to the Company, in each case, if the Board of Directors determines that
such  officer,  employee,  consultant  or  advisor  has the  capacity  to make a
substantial contribution to the success of the Company. There are [36] employees
and directors who are eligible to be granted Options under the BSYI Option Plan.
There are [__]  employees  and  directors  who hold Options under the BSC Option
Plan.

            The Shares

            Under the BSYI Option  Plan,  options to purchase up to an aggregate
of 2,500,000 shares of Common Stock may be granted, of which options to purchase
[475,000]  shares of Common  Stock  have been  granted at an  exercise  price of
[US$4.00]  per share.  Under the BSC Option  Plan,  options to purchase up to an
aggregate of  1,500,000  Exchangeable  Shares may be granted,  all of which have
been granted at exercise prices varying between $0.75 and $2.17 per share.


                                       16

<PAGE>

            Administration of the Option Plans

            The Option Plans are  administered  by the Board of Directors of the
respective  entity.  The Board of  Directors  may  delegate  its  authority  and
responsibilities to a remuneration committee (the "Compensation Committee").  If
such  delegation is made, any references to the Board of Directors  herein shall
be  applicable  to the  Compensation  Committee.  Under the terms of both Option
Plans,  the Board of Directors has the  authority to  determine,  subject to the
terms and  conditions  of the Option  Plans,  the  persons to whom  options  are
granted,  the number of shares covered by options granted to each optionee,  and
the terms and conditions of each option,  including its duration.  The aggregate
number of shares  underlying  options that may be granted at any time to any one
person is that  number of shares  that is equal to 5% of the number of shares of
the Company that are issued and outstanding at such time.

            The Option Plans may be amended, suspended, reinstated or terminated
by the Board of Directors;  provided; however, that without approval of affected
optionees, no amendment may be made that adversely affects the benefits accruing
to optionees under either of the Option Plans.

            Option Price

            Under both Option Plans,  stock options to purchase either shares of
Common Stock or  Exchangeable  Shares,  as the case may be, shall  granted at an
exercise price as  established by the Board of Directors,  but in no event shall
be lower  than the fair  market  value of the Common  Stock or the  Exchangeable
Shares, as the case maybe, as of the date of grant.

            Terms of Options

            Options  under both Option  Plans may be granted for a term of up to
10 years.  Both Option  Plans  provide  that if an Option,  or portion  thereof,
expires,   lapses  without  being  exercised  or  is  terminated,   canceled  or
surrendered  for any reason  without being  exercised in full,  the  unpurchased
shares of Common  Stock or  Exchangeable  Shares,  as the case may be, that were
subject to such Option or portion  thereof  shall be available for future grants
of stock options.

            Options  granted  under  both  Option  Plans are not  assignable  or
transferable,  except  by will  or the  laws of  intestate  succession.  Options
granted  under  both  Option  Plans may be  exercised  by the  optionee  (or the
optionee's  legal  representative)  only while the  optionee  is employed by the
Company,  or within 90 days after  termination  of employment due to a permanent
disability,   or  within  one  year  after  termination  of  employment  due  to
retirement. The executor or administrator of a deceased optionee's estate or the
person or persons to whom the deceased  optionee's rights thereunder have passed
by will or by the laws of descent and distribution shall be entitled to exercise
the  Option  within  one  year  after  the  decedent's  death.   Options  expire
immediately in the event an optionee is terminated with cause or resigns. All of
the  aforementioned  exercise periods are subject to the further limitation that
an option shall not, in any case, be  exercisable  beyond its stated  expiration
date.

            The  exercise  price and the number  and kind of shares  that may be
purchased  upon exercise of Options  granted  under both Option  Plans,  and the
number of shares subject to options that may be granted under both Option Plans,
are  subject  to  adjustment  in  certain   events,   including   stock  splits,
recapitalizations, mergers and reorganizations.

Options Granted under the Option Plan

            During the fiscal  year ended  March 31, 2000 and through the Record
Date,  options to purchase shares of Common Stock have been granted  pursuant to
the Option Plans to (i) the Chairman of the Board

                                       17


<PAGE>

and President,  (ii) the chief executive  officer,  (iii) each Director nominee,
(iv) each officer of the Company (v) all current  executive  officers as a group
and (vi) all  employees,  including  all current  officers who are not executive
officers, as a group as follows.

                        Name                         Number of Options #(1)(2)
                        ----                         -------------------------

           Amine Selmani                                       362,500
           Chairman of the Board and President

           Marie-Claire Pilon                                  175,000
           Chief Executive Officer

           Denis N. Beaudry                                     50,000
           Director

           Pierre Alary                                         50,000
           Director

           Jean-Yves Bourgeois                                  50,000
           Director

           Pierre Ranger                                        50,000
           Director

           Anthony Casola                                       50,000
           Chief Financial Officer & Secretary

           All Officers as a Group (3 persons)                 587,500


           All Employees as a Group                           [587,500]
           (3 persons)
           ------------------------------------------------------------

(1)      On the record date,  the last reported  sales price of the Common Stock
         as  reported  on the Over the  Counter  Electronic  Bulletin  Board was
         $______ per share.

(2)      Information  contained  in this  table is  duplicative  of  information
         contained in "Executive  Compensation" and does not signify  additional
         grants of options to purchase shares of common stock.

Registration of Shares

            The  Company  intends  to file a  registration  statement  under the
Securities  Act of 1933, as amended,  with respect to the Common Stock  issuable
pursuant to the BSYI Option Plan and the shares of Common  Stock  issuable  upon
the exchange of Exchangeable Shares issuable pursuant to the BSC Option Plan, if
both Option Plans are approved by the Company's stockholders.

Required Vote

            The affirmative vote of a majority of the votes cast is required for
approval of the adoption of the Option  Plans.  An  abstention,  withholding  of
authority to vote or broker  non-vote,  therefore,  will not have

                                       18

<PAGE>

the  same  legal  effect  as an  "against"  vote  and  will  not be  counted  in
determining whether the proposal has received the requisite stockholder vote.

                 THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR"
         THE APPROVAL OF THE ADOPTION OF THE STOCK OPTION INCENTIVE PLAN
                  OF EACH OF THE COMPANY AND BIO SYNTECH CANADA


                                 PROPOSAL NO. 4
              RATIFICATION OF SELECTION OF AUDITORS OF THE COMPANY

            The Board of Directors appointed Ernst & Young LLP, certified public
accountants,  as the Company's  independent  auditors for the fiscal year ending
March  31,  2001.   Although  the   selection  of  auditors   does  not  require
ratification,  the Board of Directors has directed that the appointment of Ernst
&  Young  LLP  be  submitted  to  stockholders   for  ratification  due  to  the
significance of such  appointment to the Company.  If stockholders do not ratify
the  appointment  of Ernst & Young LLP, the Board of Directors will consider the
appointment of other certified public accountants.

            The Company's auditors for the fiscal year ended March 31, 2000 were
Ernst  &  Young  LLP.  Ernst  &  Young  LLP  has  advised  the  Company  that  a
representative  will be  present  at the  Annual  Meeting  at which time he will
respond to appropriate  questions  submitted by stockholders  and will make such
statements as he may desire.

Required Vote

            The  approval of the proposal to ratify the  appointment  of Ernst &
Young LLP requires the affirmative vote of a majority of the votes cast.

                 THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR"
                      THE RATIFICATION OF ERNST & YOUNG LLP


                              STOCKHOLDER PROPOSALS

            Stockholder  proposals made in accordance  with Rule 14a-8 under the
Exchange Act and intended to be presented at the Company's  2001 Annual  Meeting
of  Stockholders  must be  received by the  Company at its  principal  office in
Laval,  Quebec,  Canada no later than May 20,  2001 for  inclusion  in the proxy
statement for that meeting.

            In addition,  the Company's  Bylaws require that a stockholder  give
advance  notice to the  Company  of  nominations  for  election  to the Board of
Directors and of other matters that the stockholder wishes to present for action
at an annual  meeting  of  stockholders  (other  than  matters  included  in the
Company's  proxy statement in accordance  with Rule 14a-8).  Such  stockholder's
notice must be given in writing,  include the information required by the Bylaws
of the Company,  and be  delivered or mailed by first class United  States mail,
postage prepaid,  to the Secretary of the Company at its principal offices.  The
Company  must receive such notice not less than 45 days prior to the date in the
current year that corresponds to the date in the prior year on which the Company
first  mailed  its  proxy  materials  for the prior  year's  annual  meeting  of
stockholders.  While  the  Company  has not yet set the date of its 2001  Annual
Meeting of  Stockholders,  if it were held on  November  30, 2001 (the date that
corresponds to the date on which the Annual Meeting is being held),  notice of a
director  nomination or  stockholder  proposal


                                       19

<PAGE>

made otherwise than in accordance  with Rule 14a-8 would be required to be given
to the Company no later than September 17, 2001.


                                  ANNUAL REPORT

            All stockholders of record as of the Record Date, have been sent, or
are  concurrently  herewith being sent, a copy of the Company's Annual Report on
Form 10-KSB for the fiscal year ended March 31, 2000,  which contains  certified
financial statements of the Company for the fiscal year ended March 31, 2000.


                                  OTHER MATTERS

            The  Board of  Directors  knows of no other  business  that  will be
presented  to the Annual  Meeting.  If any other  business is  properly  brought
before the Annual Meeting, it is intended that proxies in the enclosed form will
be voted with respect to any such matters in accordance with the judgment of the
persons voting the proxies.


                                 By Order of the Board of Directors,

                                 Anthony Casola
                                 Chief Financial Officer & Secretary



                                       20
<PAGE>

                                                                         ANNEX I

                  AMENDED AND RESTATED ARTICLES OF INCOPORATION

                                       of

                                BioSyntech, Inc.

1.          The name of this corporation is:

                                BioSyntech, Inc.

2.          Offices for the transaction of any business of the Corporation,  and
            where meetings of the Board of Directors and of Stockholders  may be
            held, may be established  and maintained in any part of the State of
            Nevada,  or in any other  state,  territory,  or  possession  of the
            United States

3.          The nature of the business is to engage in any lawful activity.

4.          The Capital  Stock shall consist of  [100,000,000]  shares of common
            stock,  $0.001 par value;  and 5,000,000  shares of Preferred Stock,
            par value $.001 per share ("Preferred Stock")."

            "Preferred Stock. The Board of Directors is expressly  authorized to
            provide  for the  issuance  of all or any  shares  of the  Preferred
            Stock,  in one or more series,  and to fix for each such series such
            voting  powers,  full or  limited,  or no  voting  powers,  and such
            designations,  preferences and relative, participating,  optional or
            other  special  rights  and  such  qualifications,   limitations  or
            restrictions  thereof  as  shall  be  stated  and  expressed  in the
            resolution  or  resolutions   adopted  by  the  Board  of  Directors
            providing  for  the  issue  of  such  series  (a  "Preferred   Stock
            Designation") and as may be permitted by the General Corporation Law
            of Nevada. The number of authorized shares of Preferred Stock may be
            increased or decreased  (but not below the number of shares  thereof
            then  outstanding)  by the  affirmative  vote  of the  holders  of a
            majority of the voting power of all of the then  outstanding  shares
            of capital stock of the  Corporation  entitled to vote  generally in
            the  election  of  Directors,  voting  together  as a single  class,
            without a separate  vote of the holders of the Preferred  Stock,  or
            any series  thereof,  unless a vote of any such  holders is required
            pursuant to any Preferred Stock Designation."

5.          The  members  of the  governing  board of the  corporation  shall be
            called  Directors,  of which  there  shall be no less than [3].  The
            Directors of this corporation  need not be  stockholders.  Directors
            shall be  divided  into three  classes  with each class to be nearly
            equal  in  number  as  possible,  in  accordance  with  the  General
            Corporation  Law of Nevada and as  specified  by  resolution  of the
            Board or, if the Directors in office  constitute fewer than a quorum
            of the Board, by affirmative  vote of a majority of the Directors in
            office.  The terms of office of the three classes of Directors shall
            initially be as follows:


<PAGE>

                        Class I - expires at the first succeeding annual meeting
                        of  stockholders;
                        Class  II -  expires  at the  second  succeeding  annual
                        meeting of stockholders;

                        Class  III -  expires  at the  third  succeeding  annual
                        meeting of stockholders.

            Thereafter,  the  Directors by class shall hold  staggered  terms of
three years.

6.          This corporation shall have perpetual existence.

7.          This Corporation shall have a president,  a secretary,  a treasurer,
            and a resident  agent,  to be chosen by the Board of Directors,  any
            person may hold two or more offices.

8.          The resident agent of this Corporation  shall be National  Corporate
            Research, Ltd.

9.          The Capital Stock of the corporation,  after the fixed consideration
            thereof  has  been  paid  or  performed,  shall  not be  subject  to
            assessment,  and the individual liable for the debts and liabilities
            of the  Corporation,  and  the  Amended  and  Restated  Articles  of
            Incorporation shall never be amended as the aforesaid provisions.

10.         No director or officer of the corporation shall be personally liable
            to the corporation of any of its stockholders for damages for breach
            of  fiduciary  duty as a director  or officer  involving  any act or
            omission of any such director or officer provided, however, that the
            foregoing  provision shall not eliminate or limit the liability of a
            director or officer for acts or omission  which involve  intentional
            misconduct,  fraud or a knowing  violation of law, or the payment of
            dividends  in  violation  of Section  78.300 of the  Nevada  Revised
            Statutes.  Any  repeal  or  modification  of  this  Article  of  the
            Stockholders of the Corporation shall be prospective only, and shall
            not adversely  affect any limitation on the personal  liability of a
            director  of the  Corporation  for acts or  omissions  prior to such
            repeal or modification.

I, the  undersigned,  being  the  Chief  Executive  Officer  of the  corporation
pursuant  to the  general  corporation  law of the State of Nevada , do make and
file these Amended and Restated Articles of Incorporation,  hereby declaring and
certifying that the facts within stated are true, and accordingly  have hereunto
set my hand this 1st day of December, 2000.

                                           -----------------------------------
                                           Marie-Claire Pilon
                                           475 Boulevard Armand-Frappier
                                           Laval, Quebec, Canada H7V 4B3


<PAGE>
                                                                        Annex II

                                 BIOSYNTECH INC
                           STOCK OPTION INCENTIVE PLAN


1.          NAME AND PURPOSE OF PLAN

1.1         The stock option plan constituted hereby shall be known as the Stock
Option Incentive Plan.

1.2         The  purpose  of the  Plan  is to  provide  a  means  whereby  those
Employees  of  the  Company  and  its   Subsidiaries   who  have  the  principal
responsibility  for the successful  administration and management of the Company
and whose present and potential  contributions  are important to its success can
obtain a proprietary  interest in the Company thereby providing an incentive for
continuing beneficial service to the Company.

2.          INTERPRETATION

In this Plan and in any Option, unless the context otherwise requires:

            "Board" means, at any time, the board of directors of the Company in
            office at that time;
            "Company"  means  BIOSYNTECH  INC, any of its  subsidiaries  and any
            successor or continuing  company  resulting from amalgamation of the
            Company and any other  company or  resulting  from any other form of
            corporate reorganization;
            "Employee"means an individual who is a bona fide employee, director,
            or officer of the Company  and an  individual  or entity  which is a
            consultant of the Company;
            "Employment"  means the  relationship of an individual who is a bona
            fide  employee,   director,  or  officer  of  the  Company  and  the
            relationship of an individual or entity which is a consultant of the
            Company;
            "Market  Price" on any particular day means an average of daily high
            and  low  board  lot  trading  prices  (with  no  discount)  for the
            immediately  preceding  five days on which trades  occurred,  on any
            public market on which the shares of the company are traded;
            "Option" means any option granted pursuant to the Plan;
            "Optionee" means an Employee who has been granted an Option;
            "Option  Price"  means the  price at which  Optioned  Shares  may be
            subscribed for pursuant to an Option.
            "Optioned Shares" means Shares which are the subject of an Option;
            "Plan" means the Stock Option  Incentive Plan as embodied herein and
            as from  time to time  amended  in  accordance  with the  provisions
            hereof;
            "Shares" means Common Shares without par value in the capital of the
            Company, as constituted at the effective date hereof;


<PAGE>

            "Subsidiary" has the same meaning,  with respect to the Company,  as
            that term has under the Quebec Companies Act .

2.1         The masculine  gender shall include the feminine gender and singular
shall include the plural and vice versa.

3.          SHARES SUBJECT TO THE PLAN

3.1         The  aggregate  number of Shares  which may be issued in  respect of
which Options may be granted,  at any time,  shall be 2,500,000  which number of
Shares shall include the balance of authorized and unissued Shares in respect of
which Options are  outstanding  at that time (or such number,  class and kind of
shares  which,  in  accordance  with  section  12 hereof,  shall be  substituted
therefor or into which they shall be altered) and the requisite number of Shares
shall  from  time to time be  appropriated  for the  purposes  of the  Plan  and
reserved and set aside for issue upon the due exercise of Options. If any Option
shall expire or terminate for any reason  without having been exercised in full,
any Optioned Shares not subscribed for thereunder shall be available for further
Options.

3.2         The  aggregate  number of Shares in respect of which  Options may be
granted, at any time to any one person,  shall be that number of Shares which is
equal to 5% of the  number  of  Shares  of the  Company  which  are  issued  and
outstanding  at that time, (or such number,  class and kind of shares which,  in
accordance with section 12 hereof,  shall be substituted  therefor or into which
they shall be altered).

4.          GRANT OF OPTIONS AND ADMINISTRATION OF THE PLAN

Subject  only to the express  provisions  of the Plan,  the Board shall have the
sole authority:

-           to determine, in its own discretion,  each Employee to whom, and the
            time or times at which,  and the Option Price and term for which, an
            Option  shall be  granted  and the number of  Optioned  Shares to be
            subject to the Option;
-           to determine and approve from time to time the form of Options,  and
            to  authorize  an officer or  officers  to execute  and  deliver any
            Option on behalf of the Company;
-           to interpret the Plan and to amend the Plan;
-           to modify or cancel the vesting period established in respect of any
            or all  Options,  notably  in the  case  of a  take-over  bid of the
            Company or other form of going pivate transaction;
-           to  delegate  its  authority  hereunder  or any part  thereof to the
            remuneration committee of the Board; and
-           to make all other  determinations and perform all such other actions
            as  the  Board  deems   necessary  or  advisable  to  implement  and
            administer the Plan.

                                       2

<PAGE>



4.2         In making any  determinations  under  subsection  4.1, the Board may
take into  account  the nature of the  services  rendered by the  Employee,  his
present  and  potential  contribution  to the  success  of the  Company  and its
Subsidiaries and such other factors as to the Board in its discretion shall deem
applicable  to carry  out the  purposes  of the  Plan.  The  Board  may,  in its
discretion,  authorize the granting of additional  Options to an Optionee before
an existing Option has terminated.

4.3         All decisions and  interpretations  of the Board respecting the Plan
or Options  shall be binding and  conclusive on the Company and on all Optionees
and their respective legal personal representatives and on all Employees.

5.          TERM OF OPTIONS

5.1         No Option shall be for a term longer than ten years from the date of
the granting of the Option.

6.          OPTION PRICE

6.1         The Option  Price in any Option shall not be an amount less than the
Market Price of the Optionned Shares.

7.          EXERCISE OF OPTIONS

7.1         Subject to the  provisions  of this  section and  sections 10 and 11
hereof and to any specific  vesting period  established by the Board at the time
of the grant,  each Option shall be  exercisable in whole at any time or in part
from time to time during the term thereof.

7.2         An  Option  may be  exercised  at the  applicable  times  and in the
applicable amounts by giving to the Company written notice of exercise signed by
the  Optionee  specifying  the  number  of  Shares  to  be  subscribed  for  and
accompanied  by full payment for the Shares to be  subscribed  for in cash or by
cheque certified by a Canadian chartered bank.

7.3         Except as provided in sections 9, 10 and 11 hereof, no Option may be
exercised  in whole or in part at any time  unless at the time of such  exercise
the Optionee is an Employee.

7.4         At any time the Board may,  by notice in  writing  to all  Optionees
under the Plan, require each Optionee to elect,  within such period as the Board
shall prescribe, to subscribe and pay for all the Optioned Shares then remaining
unsubscribed for under his Option, or to accept termination of his Option in the
event of his failing  within  such period to so elect or to exercise  his Option
and to subscribe and pay for all such remaining Optioned Shares.

                                       3

<PAGE>


8.          RIGHTS OF OPTIONEE

8.1         No Optionee  shall have any of the rights of a member of the Company
with respect to any Optioned  Shares until such Optioned Shares have been issued
to him upon  exercise of the Option and full  payment  therefor has been made by
him to the Company.


9.          NON-TRANSFERABILITY OF OPTIONS

            No Option shall be assignable or transferable by an Optionee and any
            purported  assignment  or  transfer  of an Option  shall be void and
            shall render the Option void,  but if the  employment or position of
            an Optionee with the Company or any of its Subsidiaries, as the case
            may be, is terminated by reason of his death,  the Optionee's  legal
            personal  representative or representatives  may exercise the Option
            in accordance with section 10.

10.         DEATH OR RETIREMENT OF OPTIONEE

10.1        If the employment or position of an Optionee with the Company or any
of its Subsidiaries, as the case may be, is terminated by reason of his death at
any time  during the term of an Option,  then,  until the  earlier of the expiry
date of the Option  specified at the time of its grant, or the date which is one
year  from  the  death of the  Optionee,  the  Option  may be  exercised  by the
Optionee's legal personal  representative or  representatives as to such maximum
number of Optioned  Shares which the Optionee would have otherwise been entitled
to exercise the Option in respect of at the date of his death.

10.2        If the employment or position of an Optionee with the Company or any
of its  Subsidiaries,  as the  case  may be,  is  terminated  by  reason  of his
retirement in accordance with the Company's  policies  relating to retirement of
Employees at any time during the term of an Option,  then,  until the earlier of
the expiry date of the Option  specified  at the time of its grant,  or the date
which is one  year  from the  retirement  of the  Optionee,  the  Option  may be
exercised by the Optionee or by the Optionee's legal personal  representative or
representatives  if the Optionee  dies within the period so specified as to such
maximum  number of Optioned  Shares which the Optionee would have otherwise been
entitled to exercise the Option in respect of at the date of his retirement.

11.         TERMINATION OF EMPLOYMENT OF OPTIONEE

11.1        If the employment or position of an Optionee with the Company or any
of its Subsidiaries, as the case may be, is terminated for any reason other than
as specified in section 10 or subsection  11.2,  then,  until the earlier of the
expiry date of the Option  specified at the time of its grant, or the date which
is 90 days from the termination of employment of the Optionee,  the Optionee may
exercise  his  Option in  respect of the  number of  Optioned  Shares  which the
Optionee was  entitled to subscribe  and pay for under the Option on the date of
termination of his employment.

                                       4

<PAGE>


11.2        If the employment or position of an Optionee with the Company or any
of its  Subsidiaries,  as the case may be, is  terminated  by the Company or any
Subsidiary for lawful cause,  all of the rights of the Optionee under his Option
shall terminate and the Option shall become null and void effective  immediately
upon such termination taking effect.

11.3        Nothing  contained  in the Plan or any  Option  shall  confer on any
Optionee any right to, or guarantee  of continued  employment  by the Company or
any Subsidiary,  or in any way limit the right of the Company or a Subsidiary to
terminate the employment of the Optionee at any time.

12.         CHANGES IN CAPITALIZATION OR NUMBER OF OUTSTANDING SHARES

12.1        If, and  whenever,  prior to the  issuance by the Company of all the
Optioned Shares under an Option,  the Shares are from time to time  consolidated
into a lesser  number of Shares or subdivided  into a greater  number of Shares,
the number of  Optioned  Shares  remaining  unissued  under the Option  shall be
decreased or increased proportionately, as the case may be, and the subscription
price  to be  paid by the  Optionee  for  each  such  Share  shall  be  adjusted
accordingly.

12.2        If from time to time any other  change is made in the capital of the
Company or the Company amalgamates or combines,  merges or consolidates with one
or more  other  companies  or  corporations  (and the  right so to do is  hereby
expressly reserved by the Company) whether by way of arrangement, by exchange of
shares, or otherwise, in each such case each Option shall, unless the provisions
of paragraph 7.4 are made applicable,  extend to and cover the number, class and
kind of shares or other obligations to which the holder of the Option would have
been entitled had the Option been fully exercised  immediately prior to the date
such amalgamation,  merger,  combination or consolidation  becomes effective and
the then  prevailing  subscription  price of the Shares or other  obligations so
covered  shall be  correspondingly  adjusted if and to the extent that the Board
considers it to be equitable and appropriate.

12.3        Except as  expressly  provided in this  section 12, the issue by the
Company of shares of any class, or of securities  convertible into shares of any
class, for cash or property, or for labour or services,  either upon direct sale
or upon the  exercise  of rights or  warrants  to  subscribe  therefor,  or upon
conversion of shares or obligations of the Company  convertible into such shares
or other securities, shall not affect, and no adjustment by reason thereof shall
be made with respect to, the number of Optioned Shares.

12.4        No Option  shall in any way affect the right or power of the Company
or its members to make or authorize any or all  adjustments,  recapitalizations,
reorganizations  or other changes in the capital structure of the Company or its
business,  or any  amalgamation,  combination,  merger or  consolidation  of the
Company,  or any issue of bonds  debentures,  shares  with  special  rights  and
restrictions  ranking ahead of or affecting the shares or the rights thereof, or
the dissolution or liquidation of the Company, or any sale or transfer of all or
any part of its assets or business  or

                                       5

<PAGE>

any  other  corporate  act or  proceeding,  whether  of a similar  character  or
otherwise.

13.         AMENDMENT AND TERMINATION OF THE PLAN

13.1        The Board may at any time terminate the Plan or make such amendments
to the Plan as it shall deem  advisable  provided  that no such  termination  or
amendment shall adversely affect any outstanding  Option except with the consent
of all affected Optionees.

14.         RIGHT TO OPTIONS

14.1        Nothing  contained herein or in any resolution  adopted or hereafter
adopted  by the Board or any action  taken by the Board  shall vest the right in
any person  whomsoever to receive any Option. No person shall acquire any of the
rights of an Optionee unless and until a written Option, in form satisfactory to
the Board,  shall have been duly executed on behalf of the Company and delivered
to the Optionee and executed and  delivered by the Optionee to the Company.  Any
agreement  purporting to be an Option shall, to the extent it may be contrary to
the express provisions of the Plan, be unenforceable by the Optionee against the
Company.

15.         REGULATORY AND STOCK EXCHANGE APPROVALS OR CONSENTS

15.1        The Plan and all  Options  are  subject to all  consents,  receipts,
approvals or other  authorization by any securities  commission,  administrative
agency,  other  governmental  authority or stock exchange on which shares in the
capital of the Company are or may become listed, which are requisite to the Plan
and the granting of Options.

16.         EFFECTIVE DATE OF THE PLAN

16.1        The Plan shall  become  effective  when it has been  approved by the
Board and all requisite consents,  receipts,  approvals or other  authorizations
have been obtained and complied with.


                                       6
<PAGE>
                                                                       Annex III

                             BIO SYNTECH CANADA INC
                           STOCK OPTION INCENTIVE PLAN


1.          NAME AND PURPOSE OF PLAN

1.1 The stock option plan constituted  hereby shall be known as the Stock Option
Incentive Plan.

1.2 The purpose of the Plan is to provide a means whereby those Employees of the
Company  and its  Subsidiaries  who have the  principal  responsibility  for the
successful  administration  and  management of the Company and whose present and
potential  contributions  are  important to its success can obtain a proprietary
interest in the Company thereby providing an incentive for continuing beneficial
service to the Company.

2.          INTERPRETATION

In this Plan and in any Option, unless the context otherwise requires:

            "Board" means, at any time, the board of directors of the Company in
            office at that time;
            "Company"  means  BIOSYNTECH  INC, any of its  subsidiaries  and any
            successor or continuing  company  resulting from amalgamation of the
            Company and any other  company or  resulting  from any other form of
            corporate reorganization;
            "Employee"means an individual who is a bona fide employee, director,
            or officer of the Company  and an  individual  or entity  which is a
            consultant of the Company;
            "Employment"  means the  relationship of an individual who is a bona
            fide  employee,   director,  or  officer  of  the  Company  and  the
            relationship of an individual or entity which is a consultant of the
            Company;
            "Market  Price" on any particular day means an average of daily high
            and  low  board  lot  trading  prices  (with  no  discount)  for the
            immediately  preceding  five days on which trades  occurred,  on any
            public market on which the shares of the company are traded;
            "Option" means any option granted pursuant to the Plan;
            "Optionee" means an Employee who has been granted an Option;
            "Option  Price"  means the  price at which  Optioned  Shares  may be
            subscribed for pursuant to an Option.
            "Optioned Shares" means Shares which are the subject of an Option;
            "Plan" means the Stock Option  Incentive Plan as embodied herein and
            as from  time to time  amended  in  accordance  with the  provisions
            hereof;
            "Shares" means Common Shares without par value in the capital of the
            Company, as constituted at the effective date hereof;


<PAGE>


            "Subsidiary" has the same meaning,  with respect to the Company,  as
            that term has under the Quebec Companies Act .

2.1         The masculine  gender shall include the feminine gender and singular
            shall include the plural and vice versa.

3.          SHARES SUBJECT TO THE PLAN

3.1         The  aggregate  number of Shares  which may be issued in  respect of
which Options may be granted,  at any time,  shall be 1,500,000  which number of
Shares shall include the balance of authorized and unissued Shares in respect of
which Options are  outstanding  at that time (or such number,  class and kind of
shares  which,  in  accordance  with  section  12 hereof,  shall be  substituted
therefor or into which they shall be altered) and the requisite number of Shares
shall  from  time to time be  appropriated  for the  purposes  of the  Plan  and
reserved and set aside for issue upon the due exercise of Options. If any Option
shall expire or terminate for any reason  without having been exercised in full,
any Optioned Shares not subscribed for thereunder shall be available for further
Options.

3.2         The  aggregate  number of Shares in respect of which Options may be
granted, at any time to any one person,  shall be that number of Shares which is
equal to 5% of the  number  of  Shares  of the  Company  which  are  issued  and
outstanding  at that time, (or such number,  class and kind of shares which,  in
accordance with section 12 hereof,  shall be substituted  therefor or into which
they shall be altered).

4.          GRANT OF OPTIONS AND ADMINISTRATION OF THE PLAN

Subject  only to the express  provisions  of the Plan,  the Board shall have the
sole authority:

-           to determine, in its own discretion,  each Employee to whom, and the
            time or times at which,  and the Option Price and term for which, an
            Option  shall be  granted  and the number of  Optioned  Shares to be
            subject to the Option;
-           to determine and approve from time to time the form of Options,  and
            to  authorize  an officer or  officers  to execute  and  deliver any
            Option on behalf of the Company;
-           to interpret the Plan and to amend the Plan;
-           to modify or cancel the vesting period established in respect of any
            or all  Options,  notably  in the  case  of a  take-over  bid of the
            Company or other form of going pivate transaction;
-           to  delegate  its  authority  hereunder  or any part  thereof to the
            remuneration committee of the Board; and
-           to make all other  determinations and perform all such other actions
            as  the  Board  deems   necessary  or  advisable  to  implement  and
            administer the Plan.

                                       2

<PAGE>

4.2         In making any  determinations  under  subsection  4.1, the Board may
take into  account  the nature of the  services  rendered by the  Employee,  his
present  and  potential  contribution  to the  success  of the  Company  and its
Subsidiaries and such other factors as to the Board in its discretion shall deem
applicable  to carry  out the  purposes  of the  Plan.  The  Board  may,  in its
discretion,  authorize the granting of additional  Options to an Optionee before
an existing Option has terminated.

4.3         All decisions and  interpretations  of the Board respecting the Plan
or Options  shall be binding and  conclusive on the Company and on all Optionees
and their respective legal personal representatives and on all Employees.

5.          TERM OF OPTIONS

5.1         No Option shall be for a term longer than ten years from the date of
the granting of the Option.

6.          OPTION PRICE

6.1         The Option  Price in any Option shall not be an amount less than the
Market Price of the Optionned Shares.

7.          EXERCISE OF OPTIONS

7.1         Subject to the  provisions  of this  section and  sections 10 and 11
hereof and to any specific  vesting period  established by the Board at the time
of the grant,  each Option shall be  exercisable in whole at any time or in part
from time to time during the term thereof.

7.2         An  Option  may be  exercised  at the  applicable  times  and in the
applicable amounts by giving to the Company written notice of exercise signed by
the  Optionee  specifying  the  number  of  Shares  to  be  subscribed  for  and
accompanied  by full payment for the Shares to be  subscribed  for in cash or by
cheque certified by a Canadian chartered bank.

7.3         Except as provided in sections 9, 10 and 11 hereof, no Option may be
exercised  in whole or in part at any time  unless at the time of such  exercise
the Optionee is an Employee.

7.4         At any time the Board may,  by notice in  writing  to all  Optionees
under the Plan, require each Optionee to elect,  within such period as the Board
shall prescribe, to subscribe and pay for all the Optioned Shares then remaining
unsubscribed for under his Option, or to accept termination of his Option in the
event of his failing  within  such period to so elect or to exercise  his Option
and to subscribe and pay for all such remaining Optioned Shares.

                                       3
<PAGE>

8.          RIGHTS OF OPTIONEE

8.1         No Optionee  shall have any of the rights of a member of the Company
with respect to any Optioned  Shares until such Optioned Shares have been issued
to him upon  exercise of the Option and full  payment  therefor has been made by
him to the Company.


9.          NON-TRANSFERABILITY OF OPTIONS

            No Option shall be assignable or transferable by an Optionee and any
            purported  assignment  or  transfer  of an Option  shall be void and
            shall render the Option void,  but if the  employment or position of
            an Optionee with the Company or any of its Subsidiaries, as the case
            may be, is terminated by reason of his death,  the Optionee's  legal
            personal  representative or representatives  may exercise the Option
            in accordance with section 10.

10.         DEATH OR RETIREMENT OF OPTIONEE

10.1        If the employment or position of an Optionee with the Company or any
of its Subsidiaries, as the case may be, is terminated by reason of his death at
any time  during the term of an Option,  then,  until the  earlier of the expiry
date of the Option  specified at the time of its grant, or the date which is one
year  from  the  death of the  Optionee,  the  Option  may be  exercised  by the
Optionee's legal personal  representative or  representatives as to such maximum
number of Optioned  Shares which the Optionee would have otherwise been entitled
to exercise the Option in respect of at the date of his death.

10.2        If the employment or position of an Optionee with the Company or any
of its  Subsidiaries,  as the  case  may be,  is  terminated  by  reason  of his
retirement in accordance with the Company's  policies  relating to retirement of
Employees at any time during the term of an Option,  then,  until the earlier of
the expiry date of the Option  specified  at the time of its grant,  or the date
which is one  year  from the  retirement  of the  Optionee,  the  Option  may be
exercised by the Optionee or by the Optionee's legal personal  representative or
representatives  if the Optionee  dies within the period so specified as to such
maximum  number of Optioned  Shares which the Optionee would have otherwise been
entitled to exercise the Option in respect of at the date of his retirement.

11.         TERMINATION OF EMPLOYMENT OF OPTIONEE

11.1        If the employment or position of an Optionee with the Company or any
of its Subsidiaries, as the case may be, is terminated for any reason other than
as specified in section 10 or subsection  11.2,  then,  until the earlier of the
expiry date of the Option  specified at the time of its grant, or the date which
is 90 days from the termination of employment of the Optionee,  the Optionee may
exercise  his  Option in  respect of the  number of  Optioned  Shares  which the
Optionee was  entitled to subscribe  and pay for under the Option on the date of
termination of his employment.


                                       4
<PAGE>



11.2        If the employment or position of an Optionee with the Company or any
of its  Subsidiaries,  as the case may be, is  terminated  by the Company or any
Subsidiary for lawful cause,  all of the rights of the Optionee under his Option
shall terminate and the Option shall become null and void effective  immediately
upon such termination taking effect.

11.3        Nothing  contained  in the Plan or any  Option  shall  confer on any
Optionee any right to, or guarantee  of continued  employment  by the Company or
any Subsidiary,  or in any way limit the right of the Company or a Subsidiary to
terminate the employment of the Optionee at any time.

12.         CHANGES IN CAPITALIZATION OR NUMBER OF OUTSTANDING SHARES

12.1        If, and  whenever,  prior to the  issuance by the Company of all the
Optioned Shares under an Option,  the Shares are from time to time  consolidated
into a lesser  number of Shares or subdivided  into a greater  number of Shares,
the number of  Optioned  Shares  remaining  unissued  under the Option  shall be
decreased or increased proportionately, as the case may be, and the subscription
price  to be  paid by the  Optionee  for  each  such  Share  shall  be  adjusted
accordingly.

12.2        If from time to time any other  change is made in the capital of the
Company or the Company amalgamates or combines,  merges or consolidates with one
or more  other  companies  or  corporations  (and the  right so to do is  hereby
expressly reserved by the Company) whether by way of arrangement, by exchange of
shares, or otherwise, in each such case each Option shall, unless the provisions
of paragraph 7.4 are made applicable,  extend to and cover the number, class and
kind of shares or other obligations to which the holder of the Option would have
been entitled had the Option been fully exercised  immediately prior to the date
such amalgamation,  merger,  combination or consolidation  becomes effective and
the then  prevailing  subscription  price of the Shares or other  obligations so
covered  shall be  correspondingly  adjusted if and to the extent that the Board
considers it to be equitable and appropriate.

12.3        Except as  expressly  provided in this  section 12, the issue by the
Company of shares of any class, or of securities  convertible into shares of any
class, for cash or property, or for labour or services,  either upon direct sale
or upon the  exercise  of rights or  warrants  to  subscribe  therefor,  or upon
conversion of shares or obligations of the Company  convertible into such shares
or other securities, shall not affect, and no adjustment by reason thereof shall
be made with respect to, the number of Optioned Shares.

12.4        No Option  shall in any way affect the right or power of the Company
or its members to make or authorize any or all  adjustments,  recapitalizations,
reorganizations  or other changes in the capital structure of the Company or its
business,  or any  amalgamation,  combination,  merger or  consolidation  of the
Company,  or any issue of bonds  debentures,  shares  with  special  rights  and
restrictions  ranking ahead of or affecting the shares or the rights thereof, or
the dissolution or liquidation of the Company, or any sale or transfer of all or
any part of its assets or business  or

                                       5
<PAGE>

any  other  corporate  act or  proceeding,  whether  of a similar  character  or
otherwise.

13.         AMENDMENT AND TERMINATION OF THE PLAN

13.1        The Board may at any time terminate the Plan or make such amendments
to the Plan as it shall deem  advisable  provided  that no such  termination  or
amendment shall adversely affect any outstanding  Option except with the consent
of all affected Optionees.

14.         RIGHT TO OPTIONS

14.1        Nothing  contained herein or in any resolution  adopted or hereafter
adopted  by the Board or any action  taken by the Board  shall vest the right in
any person  whomsoever to receive any Option. No person shall acquire any of the
rights of an Optionee unless and until a written Option, in form satisfactory to
the Board,  shall have been duly executed on behalf of the Company and delivered
to the Optionee and executed and  delivered by the Optionee to the Company.  Any
agreement  purporting to be an Option shall, to the extent it may be contrary to
the express provisions of the Plan, be unenforceable by the Optionee against the
Company.

15.         REGULATORY AND STOCK EXCHANGE APPROVALS OR CONSENTS

15.1        The Plan and all  Options  are  subject to all  consents,  receipts,
approvals or other  authorization by any securities  commission,  administrative
agency,  other  governmental  authority or stock exchange on which shares in the
capital of the Company are or may become listed, which are requisite to the Plan
and the granting of Options.

16.         EFFECTIVE DATE OF THE PLAN

16.1        The Plan shall  become  effective  when it has been  approved by the
Board and all requisite consents,  receipts,  approvals or other  authorizations
have been obtained and complied with.


                                       6
<PAGE>




                                BIOSYNTECH, INC.

               PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

                       2000 ANNUAL MEETING OF STOCKHOLDERS

                                NOVEMBER 30, 2000

            The   undersigned   hereby   appoints  each  of  Amine  Selmani  and
Marie-Claire Pilon as the undersigned's  proxy, with full power of substitution,
to vote all of the undersigned's shares of Common Stock in BioSyntech, Inc. (the
"Company"), at the 2000 Annual Meeting of Stockholders of the Company to be held
on November 30, 2000 at 11:00 A.M. local time, at ___________________, or at any
adjournment,  on the matters  described in the Notice of 2000 Annual Meeting and
Proxy  Statement  and upon such other  business as may properly come before such
meeting or any  adjournments  thereof,  hereby  revoking any proxies  heretofore
given.

PROPOSAL 1        Approve the  adoption of the  Company's  Amended and  Restated
                  Articles of Incorporation:

                  FOR    /   /       AGAINST   /   /              ABSTAIN /   /

PROPOSAL 2        The election of Dr. Amine  Selmani,  Denis N. Beaudry,  Pierre
                  Alary,  Jean-Yves Bourgeois,  Dr. Pierre Ranger,  Marie-Claire
                  Pilon:

                                                      Withhold Authority
                  For All                             To Vote For All
                  Nominees  ___                       Nominees  ___

                  ---------------------------------------------------
                  ---------------------------------------------------
                  To withhold  authority to vote for any individual  nominee(s),
                  print names above.

PROPOSAL 3        Approve the adoption of the Company's  Stock Option  Incentive
                  Plan and Bio Syntech  Canada,  Inc.'s Stock  Option  Incentive
                  Plan:

                  FOR    /   /       AGAINST   /   /              ABSTAIN /   /

PROPOSAL 4        Ratify the  appointment  of Ernst & Young LLP as the Company's
                  auditors for the fiscal year ending March 31, 2001:

                  FOR    /   /       AGAINST   /   /              ABSTAIN /   /

                  (continued and to be signed on reverse side)

                                       21

<PAGE>


Each properly  executed  proxy will be voted in accordance  with  specifications
made on the reverse  side  hereof.  If no  specifications  are made,  the shares
represented by this Proxy will be voted for approval of Proposals 1, 2, 3 and 4.


                                    --------------------------------------------
                                    Signature

                                    --------------------------------------------
                                    Signature if held jointly

                                    Dated:  ___________, 2000

                                    Please sign exactly as set forth herein.  If
                                    signed as executor, attorney, administrator,
                                    trustee or  guardian,  indicate the capacity
                                    in which you are  acting.  When  signing  as
                                    joint  tenants,  all  parties  in the  joint
                                    tenancy should sign. Proxies by corporations
                                    should be signed with full corporate name by
                                    a duly authorized officer and bear corporate
                                    seal.

Please promptly sign and return the Proxy Card in the enclosed envelope.

                                       22



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