ANTIGENICS INC /DE/
S-8, 2000-11-21
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1

    As filed with the Securities and Exchange Commission on November 21, 2000

                                                     REGISTRATION NO. 333-


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM S-8
                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933


                                 ANTIGENICS INC.
             (Exact Name of Registrant as Specified in its Charter)


         DELAWARE                                                06-1562417
     (State or Other                                          (I.R.S. Employer
Jurisdiction of Incorporation)                               Identification No.)


             630 FIFTH AVENUE, SUITE 2100, NEW YORK, NEW YORK 10111
                    (Address of Principal Executive Offices)


       AQUILA BIOPHARMACEUTICALS, INC. 1996 STOCK AWARD AND OPTION PLAN
   AQUILA BIOPHARMACEUTICALS, INC. 1996 DIRECTORS STOCK AWARD AND OPTION PLAN
                        (AS ASSUMED BY ANTIGENICS INC.)
                            (Full Title of the Plan)

                              GARO H. ARMEN, PH.D.
                             Chief Executive Officer
                                 Antigenics Inc.
                          630 Fifth Avenue, Suite 2100
                            New York, New York 10111
                                 (212) 332-4774
            (Name, Address and Telephone Number of Agent for Service)

                                 with copies to:

                              MICHAEL LYTTON, ESQ.
                               Palmer & Dodge LLP
                                One Beacon Street
                           Boston, Massachusetts 02108
                                 (617) 573-0100

                         CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
----------------------------------------------------------------------------------------------------------------
                                                          Proposed maximum     Proposed maximum       Amount of
Title of each class of securities       Amount to be     offering price per   aggregate offering    registration
         to be registered               registered(1)         share(2)             price(2)              fee
----------------------------------------------------------------------------------------------------------------
<S>                                    <C>                     <C>               <C>                    <C>

Aquila Biopharmaceuticals, Inc.
 1996 Stock Award and Option Plan:

Common Stock, $0.01 par value          205,489 shares          $12.20            $2,506,966             $662

Aquila Biopharmaceuticals, Inc.
 1996 Directors Stock Award and
 Option Plan:

Common Stock, $0.01 par value           59,031 shares          $10.94            $  645,800             $171
                                       -------                                   ----------             ----
Total                                  264,520                                   $3,152,766             $833
----------------------------------------------------------------------------------------------------------------
</TABLE>

(1)  Pursuant to Rule 416 under the Securities Act of 1933, to the extent
     additional shares of our common stock may be issued or issuable as a result
     of a stock split or other distribution declared at any time by the Board of
     Directors while this registration statement is in effect, this registration
     statement is hereby deemed to cover all such additional shares of common
     stock.

(2)  Estimated solely for the purpose of determining the registration fee and
     computed pursuant to Rule 457(h)(1). The proposed maximum offering price
     per share indicated is based on the weighted average price per share in
     effect for the outstanding options under the Aquila Biopharmaceuticals,
     Inc. 1996 Stock Award and Option Plan and the Aquila Biopharmaceuticals,
     Inc. 1996 Directors Stock Award and Option Plan as assumed by Antigenics
     Inc.





<PAGE>   2

                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF DOCUMENTS BY REFERENCE.

         The following documents previously filed with the Securities and
Exchange Commission are incorporated by reference herein and shall be deemed as
part hereof:

         (a)      the proxy statement/prospectus (File No. 333-46168) filed
                  under the Securities Act of 1933, as amended (the "Securities
                  Act"), on October 4, 2000;

         (b)      all of our other reports filed pursuant to Section 13(a) or
                  15(d) of the Securities Exchange Act of 1934, as amended (the
                  "Exchange Act"), since December 31, 1999; and

         (c)      the description of our common stock contained in our
                  Registration Statement on Form 8-A filed on January 24, 2000,
                  including any amendment or report filed hereafter for the
                  purpose of updating such description.

         All documents filed after the date of this registration statement
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act and prior to
the filing of a post-effective amendment that indicates that all shares of
common stock offered hereunder have been sold or that deregisters all shares of
common stock remaining unsold shall be deemed to be incorporated by reference
herein and to be a part hereof from the date of the filing of such reports and
documents. Any statement contained in a document incorporated or deemed to be
incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this registration statement to the extent that a statement
contained herein or in any other subsequently filed document that also is or is
deemed to be incorporated by reference herein modifies or supersedes such
statement. Any statement so modified or superseded shall not be deemed, except
as so modified or superseded, to constitute as part of this registration
statement.

ITEM 4.  DESCRIPTION OF SECURITIES.

         Not applicable.

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

         Not applicable.

ITEM 6.  INDEMNIFICATION OF OFFICERS AND DIRECTORS.

         Section 145 of the Delaware General Corporation Law provides that a
corporation may indemnify any person who was or is a party or is threatened to
be made a party to any threatened, pending or completed action, suit or
proceeding, whether civil, criminal, administrative or investigative, other than
an action by or in the right of the corporation, by reason of the fact that the
person is or was a director, officer, employee or agent of the corporation or is
or was serving at the corporation's request as a director, officer, employee or
agent of another corporation, partnership, joint venture, trust or other
enterprise, against expenses, including attorneys' fees, judgments, fines and
amounts paid in settlement actually and reasonably incurred by the person in
connection with the action, suit or proceeding if the person acted in good faith
and in a manner the person reasonably believed to be in or not opposed to the
best interests of the corporation, and, with respect to any criminal action or
proceeding, had no reasonable cause to believe the person's conduct was
unlawful. The power to indemnify applies to actions brought by or in the right
of the corporation as well, but only to the extent of expenses, including
attorneys' fees but excluding judgments, fines and amounts paid in settlement,
actually and reasonably incurred by the person in connection with the defense or
settlement of the action or suit. In these actions no indemnification shall be
made in the event of any adjudication of negligence or misconduct in the
performance of his duties to the corporation, unless a court believes that in
light of all the circumstances indemnification should apply.




                                       2
<PAGE>   3
         Article V of Antigenics' By-laws provides that Antigenics shall, to the
extent legally permitted, indemnify each person who was or is a party or is
threatened to be made a party to any threatened, pending or completed action,
suit or proceeding by reason of the fact that he is or was, or has agreed to
become, a director or officer of Antigenics, or is or was serving, or has agreed
to serve, at the request of Antigenics, as a director, officer or trustee of, or
in a similar capacity with, another corporation, partnership, joint venture,
trust or other enterprises. The indemnification provided for in Article V is
expressly not exclusive of any other rights to which those seeking
indemnification may be entitled under any law, agreement or vote of stockholders
or disinterested directors or otherwise, and shall inure to the benefit of the
heirs, executors and administrators of such persons.

         Section 145(g) of the Delaware General Corporation Law and Article V of
By-laws of Antigenics provide that the company shall have the power to purchase
and maintain insurance on behalf of its officers, directors, employees and
agents, against any liability asserted against and incurred by such persons in
any such capacity.

         Antigenics has entered into indemnification agreements with each of its
directors and executive officers and has obtained insurance covering its
directors and officers against losses and insuring Antigenics against certain of
its obligations to indemnify its directors and officers.

         Section 102(b)(7) of the General Corporation Law of the State of
Delaware provides that a corporation may eliminate or limit the personal
liability of a director to the corporation or its stockholders for monetary
damages for breach of fiduciary duty as a director, provided that such
provisions shall not eliminate or limit the liability of a director (i) for any
breach of the director's duty of loyalty to the corporation or its stockholders,
(ii) for acts or omissions not in good faith or which involve intentional
misconduct or a knowing violation of law, (iii) under Section 174 of the General
Corporation Law of the State of Delaware, or (iv) for any transaction from which
the director derived an improper personal benefit. No such provision shall
eliminate or limit the liability of a director for any act or omission occurring
prior to the date when such provision becomes effective.

         Pursuant to the Delaware General Corporation Law, Section 6 of Article
FIFTH of the Certificate of Incorporation of Antigenics eliminates a director's
personal liability for monetary damages to Antigenics and its stockholders for
breach of fiduciary duty as a director, except in circumstances involving a
breach of the director's duty of loyalty to Antigenics or its stockholders, acts
or omissions not in good faith, intentional misconduct, knowing violations of
the law, self-dealing or the unlawful payment of dividends or repurchase of
stock.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED.

         Not applicable.

ITEM 8.  EXHIBITS.

         See Exhibit Index immediately following signature pages.

ITEM 9.  UNDERTAKINGS.

         (a)      The undersigned registrant hereby undertakes:

                  (1)      To file, during any period in which offers or sales
are being made, a post-effective amendment to this registration statement:

                           (i)      To include any prospectus required by
Section 10 (a)(3) of the Securities Act of 1933;

                           (ii)     To reflect in the prospectus any facts or
events arising after the effective date of this registration statement (or the
most recent post-effective amendment thereof) which, individually or in the
aggregate, represents a fundamental change in the information set forth in this
registration statement;

                           (iii)    To include any material information with
respect to the plan of distribution not previously disclosed in this
registration statement or any material change to such information in this
registration


                                       3
<PAGE>   4
statement; provided, however, that paragraphs (a) (1) (i) and (a) (1) (ii) do
not apply if the information required to be included in a post-effective
amendment by those paragraphs is contained in periodic reports filed with or
furnished to the Commission by the registrant pursuant to Section 13 or Section
15(d) of the Exchange Act of 1934 that are incorporated by reference in this
registration statement.

                  (2)      That, for the purpose of determining any liability
under the Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the securities offered
therein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.

                  (3)      To remove from registration by means of a
post-effective amendment any of the securities being registered which remain
unsold at the termination of the offering.

         (b)      The undersigned registrant hereby undertakes that, for
purposes of determining any liability under the Securities Act of 1933, each
filing of the registrant's annual report pursuant to Section 13(a) or Section
15(d) of the Exchange Act of 1934 that is incorporated by reference in this
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein and the offering of such securities
at that time shall be deemed to be initial bona fide offering thereof.

         (c)      Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers and controlling
persons of the registrant pursuant to the provisions referred to in Item 6
hereof, or otherwise, the registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Securities Act of 1933 and is, therefore, unenforceable. In
the event that a claim for indemnification against such liabilities (other than
the payment by the registrant of expenses incurred or paid by a directors,
officer or controlling person of the registrant in the successful defense of any
action, suit or proceeding) is asserted by such director, officer, or
controlling person in connection with the securities being registered, the
registrant will, unless in the opinion of its counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction
the question whether such indemnification by it is against public policy as
expressed in the Securities Act of 1933 and will be governed by the final
jurisdiction of such issue.


                                       4



<PAGE>   5

                                   SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the Town of Woburn, Commonwealth of Massachusetts, as of November
21, 2000.



                                        ANTIGENICS INC.



                                        By: /s/ Garo H. Armen, Ph.D.
                                            ------------------------------------
                                            Garo H. Armen, Ph.D.
                                            Chief Executive Officer and
                                            Chairman of the Board of Directors



                                POWER OF ATTORNEY

We, the undersigned officers and directors of Antigenics Inc., hereby severally
constitute and appoint Garo H. Armen, Ph.D. and Michael Lytton and each of them
singly, our true and lawful attorneys-in-fact, with full power to them in any
and all capacities, to sign any and all amendments to this Registration
Statement on Form S-8 (including any post-effective amendments thereto), and to
file the same, with exhibits thereto and other documents in connection
therewith, with the Securities and Exchange Commission, hereby ratifying and
confirming all that each of said attorneys-in-fact may do or cause to be done by
virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this registration
statement has been signed below by the following persons in the capacities and
as of the dates indicated.

<TABLE>
<CAPTION>
SIGNATURE                        TITLE                                DATE
---------                        -----                                ----
<S>                              <C>                                 <C>

/s/ Garo H. Armen, Ph.D.         Chief Executive Officer and          November 21, 2000
-----------------------------    Chairman of the Board of
Garo H. Armen, Ph.D.             Directors (Principal Executive
                                 Officer and Principal Financial
                                 and Accounting Officer)


/s/ Pramod Srivastava, Ph.D.     Director                             November 21, 2000
-----------------------------
Pramod Srivastava, Ph.D.


/s/ Noubar Afeyan, Ph.D.         Director                             November 21, 2000
-----------------------------
Noubar Afeyan, Ph.D.


/s/ Gamil de Chadarevian         Director                             November 21, 2000
-----------------------------
Gamil de Chadarevian


/s/ Tom Dechaene                 Director                             November 21, 2000
-----------------------------
Tom Dechaene


/s/ Donald Panoz                 Director                             November 21, 2000
-----------------------------
Donald Panoz


/s/ Martin Taylor                Director                             November 21, 2000
-----------------------------
Martin Taylor

</TABLE>




                                       5
<PAGE>   6

                                  EXHIBIT INDEX


EXHIBIT
 NUMBER               DESCRIPTION
-------               -----------

   4.1      Certificate of Incorporation of Antigenics Inc. Filed as Exhibit 3.1
            to our Registration Statement on Form S-1 (File No. 333-91747) and
            incorporated herein by reference.

   4.2      By-laws of Antigenics Inc. Filed as Exhibit 3.2 to our Registration
            Statement on Form S-1 (File No. 333-91747) and incorporated herein
            by reference.

   4.3      Form of Warrant to purchase Common Stock, together with a list of
            holders. Filed as Exhibit 4.1 to our Registration Statement on Form
            S-1 (File No. 333-91747) and incorporated herein by reference.

   4.4      Form of Subscription Agreement, as amended, together with a list of
            parties thereto. Filed as Exhibit 4.2 to our Registration Statement
            on Form S-1 (File No. 333-91747) and incorporated herein by
            reference.

   5.1      Opinion of Palmer & Dodge LLP.  Filed herewith.

  23.1      Consent of KPMG LLP.  Filed herewith.

  23.2      Consent of PricewaterhouseCoopers LLP.  Filed herewith.

  23.3      Consent of Palmer & Dodge LLP. Included in the opinion filed as
            Exhibit 5.1.

  24.1      Power of Attorney.  Included on the signature page hereto.










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