PIONEER SCIENCE & TECHNOLOGY FUND
NSAR-B, EX-99.77BACCTLTTR, 2000-11-21
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Report of Independent Public Accountants

To the Board of Trustees of
Pioneer Science and Technology Fund:


In planning and  performing  our audit of the  financial  statements  of Pioneer
Science and Technology Fund for the year ended September 30, 2000, we considered
its internal control,  including control activities for safeguarding securities,
in order to determine our auditing  procedures for the purpose of expressing our
opinion on the financial  statements and to comply with the requirements of Form
N-SAR, not to provide assurance on internal control.

The  management  of Pioneer  Science  and  Technology  Fund is  responsible  for
establishing   and   maintaining    internal   control.   In   fulfilling   this
responsibility, estimates and judgments by management are required to assess the
expected  benefits and related costs of controls.  Generally,  controls that are
relevant to an audit  pertain to the entity's  objective of preparing  financial
statements for external  purposes that are fairly  presented in conformity  with
accounting  principles  generally accepted in the United States.  Those controls
include the  safeguarding of assets against  unauthorized  acquisition,  use, or
disposition.

Because of inherent  limitations in internal  control,  error or fraud may occur
and not be detected.  Also,  projection of any evaluation of internal control to
future periods is subject to the risk that it may become  inadequate  because of
changes in conditions or that the  effectiveness of the design and operation may
deteriorate.

Our consideration of internal control would not necessarily disclose all matters
in  internal   control  that  might  be  material   weaknesses  under  standards
established  by the  American  Institute  of  Certified  Public  Accountants.  A
material weakness is a condition in which the design or operation of one or more
of the internal control components does not reduce to a relatively low level the
risk  that  misstatements  caused  by error or fraud in  amounts  that  would be
material in relation to the financial statements being audited may occur and not
be  detected  within a timely  period  by  employees  in the  normal  course  of
performing  their assigned  functions.  However,  we noted no matters  involving
internal  control  and  its  operation,   including  controls  for  safeguarding
securities,  that we consider to be material  weaknesses  as defined above as of
September 30, 2000.

This report is intended solely for the  information  and use of management,  the
Board of Trustees of Pioneer  Science and Technology Fund and the Securities and
Exchange Commission.


                                                    /s/ARTHUR ANDERSEN LLP

Boston, Massachusetts
November 3, 2000




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