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VAN KAMPEN FOCUS PORTFOLIOS, SERIES 243 Morgan Stanley U.S. Multinational IndexSM Portfolio, Series 5A Morgan Stanley U.S. Multinational IndexSM Portfolio, Series 5B SUPPLEMENT TO THE PROSPECTUS Notwithstanding anything to the contrary in the prospectus, as a result of the acquisition of Bestfoods by Unilever PLC in a cash transaction, the stock of Bestfoods is no longer included in the Portfolios described above. Dated: October 5, 2000
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