<PAGE>
As filed with the United States Securities and Exchange Commission
on December 7, 2000
Registration No. 333-47706
================================================================================
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
------------------------------
Post-Effective Amendment No. 1
to
FORM S-1
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
------------------------------
DENDREON CORPORATION
(Exact name of registrant as specified in its charter)
<TABLE>
<S> <C> <C>
Delaware 2834 22-3203193
(State or Other Jurisdiction of (Primary Standard Industrial (I.R.S. Employer
Incorporation or Organization) Classification Code Number) Identification No.)
</TABLE>
3005 First Avenue
Seattle, Washington 98121
(206) 256-4545
(Address, including zip code and telephone number, including area code of
registrant's principal executive offices)
Christopher S. Henney
President and Chief Executive Officer
3005 First Avenue
Seattle, Washington 98121
(206) 256-4545
(Name, address, including zip code and telephone number, including area code of
agent for service)
------------------------------
Copies to:
Julie M. Robinson Rodd Schreiber
Cooley Godward LLP Skadden, Arps, Slate, Meagher & Flom LLP
4365 Executive Drive, Suite 1100 333 West Wacker Drive, Suite 2100
San Diego, California 92121-2128 Chicago, Illinois 60606
Tel: (858) 550-6000 Tel: (312) 407-0700
Fax: (858) 463-3555 Fax: (312) 407-0411
------------------------------
================================================================================
<PAGE>
This Post-Effective Amendment No. 1 is being filed to deregister 122,000 shares
of our common stock covered by the Form S-1 Registration Statement No. 333-
47706, as amended. The shares, which were issuable as part of the underwriter's
option to cover over-allotments, in connection with a firm commitment
underwritten offering of our common stock, were not sold within thirty (30) days
of the date of the Prospectus and are no longer being offered. The terms of the
offering are described in the Prospectus filed as part of the Registration
Statement.
2
<PAGE>
SIGNATURES
Pursuant to the requirements of the Securities Act, Dendreon Corporation and has
duly caused this Post-Effective Amendment No. 1 to the Registration Statement to
be signed on its behalf by the undersigned, thereunto duly authorized, in the
City of Seattle, King County, State of Washington, on this 6th day of December,
2000.
DENDREON CORPORATION
By: *
----------------------------------
Christopher S. Henney, Ph.D., D.Sc.
President and Chief Executive Officer
Pursuant to the requirements of the Securities Act, as amended, this Post-
Effective Amendment No. 1 to the Registration Statement has been signed by the
following persons in the capacities and on the dates indicated:
<TABLE>
<CAPTION>
Signature Title Date
<S> <C> <C>
* President, Chief Executive December 6, 2000
------------------------------------ Officer and Director
Christopher S. Henney, Ph.D., D.Sc. (Principal Executive Officer)
December 6, 2000
/s/ Martin A. Simonetti Chief Financial Officer
------------------------------------ (Principal Financial and
Martin A. Simonetti Accounting Officer)
* Chairman of the Board of Directors December 6, 2000
------------------------------------
William Crouse
* Director December 6, 2000
------------------------------------
Gerardo Canet
* Director December 6, 2000
------------------------------------
Timothy Harris, Ph.D.
* Director December 6, 2000
------------------------------------
Ruth Kunath
* Director December 6, 2000
------------------------------------
Ralph Shaw
* Director December 6, 2000
------------------------------------
David L. Urdal, Ph.D.
* Director December 6, 2000
------------------------------------
Douglas Watson
</TABLE>
* By: /s/ Martin A. Simonetti
-----------------------------------
Martin A. Simonetti
Attorney-in-Fact
3
