DISCOVERY PARTNERS INTERNATIONAL INC
S-1/A, EX-23.1, 2000-07-27
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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<PAGE>   1
                                                                    EXHIBIT 23.1


               CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS



We consent to the reference to our firm under the caption "Experts" and to the
use of our report dated March 10, 2000, except for Note 11, as to which the date
is July 27, 2000, in the Registration Statement (Form S-1) and related
Prospectus of Discovery Partners International, Inc. for the registration of
shares of its common stock.


                                     /s/ ERNST & YOUNG LLP


San Diego, California
July 27, 2000





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