<PAGE> 1
EXHIBIT 23.1
CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS
We consent to the incorporation by reference in the Registration Statement on
Form S-8 pertaining to the 2000 Stock Incentive Plan and the Employee Stock
Purchase Plan of Discovery Partners International, Inc. of our report dated
March 10, 2000, except note 11, as to which the date is July 27, 2000, with
respect to the consolidated financial statements of Discovery Partners
International, Inc. included in its Registration Statement on Form S-1, filed
with the Securities and Exchange Commission.
/s/ ERNST & YOUNG LLP
San Diego, California
August 28, 2000
