DISCOVERY PARTNERS INTERNATIONAL INC
S-1/A, EX-23.1, 2000-07-21
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                                                    EXHIBIT 23.1


               CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS



We consent to the reference to our firm under the caption "Experts" and to the
use of our report dated March 10, 2000, except for Note 11, as to which the date
is      , in the Registration Statement (Form S-1) and related Prospectus of
Discovery Partners International, Inc. for the registration of shares of its
common stock.



                                    ERNST & YOUNG LLP


San Diego, California

The foregoing consent is in the form that will be signed upon the completion of
the restatement of capital accounts described in Note 11 to the financial
statements.



                                     /s/ ERNST & YOUNG LLP


San Diego, California
July 20, 2000





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