MEDICINES CO/ MA
S-8, 2000-08-31
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
     As filed with the Securities and Exchange Commission on August 31, 2000
                                                       Registration No. 333-____
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM S-8

                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933

                              THE MEDICINES COMPANY
             (Exact Name of Registrant as Specified in Its Charter)

         DELAWARE                                        04-3324394
(State or Other Jurisdiction of                       (I.R.S. Employer
Incorporation or Organization)                       Identification No.)

ONE CAMBRIDGE CENTER, CAMBRIDGE, MASSACHUSETTS             02142
(Address of Principal Executive Offices)                 (Zip Code)

                            1998 STOCK INCENTIVE PLAN
                     2000 OUTSIDE DIRECTOR STOCK OPTION PLAN
                        2000 EMPLOYEE STOCK PURCHASE PLAN
                            (Full Title of the Plan)

                                CLIVE A. MEANWELL
                             CHIEF EXECUTIVE OFFICER
                              THE MEDICINES COMPANY
                              ONE CAMBRIDGE CENTER
                         CAMBRIDGE, MASSACHUSETTS 02142
                     (Name and Address of Agent for Service)
                                 (617) 225-9099
          (Telephone number, Including Area Code, of Agent For Service)

                         CALCULATION OF REGISTRATION FEE
<TABLE>
<CAPTION>

================================================================================================================
Title of Each Class                               Proposed Maximum       Proposed Maximum
of Securities to                                 Offering Price Per     Aggregate Offering          Amount of
be  Registered        Amount to be Registered           Share                  Price            Registration Fee
----------------------------------------------------------------------------------------------------------------
<S>                <C>                        <C>                    <C>                    <C>
Common Stock,
$0.001 par value          4,873,759 shares           $18.938(1)           $92,299,248(1)           $24,367(1)
per share
================================================================================================================
</TABLE>

(1)  Estimated solely for the purpose of calculating the registration fee
     pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as
     amended, and based upon the average of the high and low prices of the
     Registrant's Common Stock as reported on the Nasdaq National Market on
     August 30, 2000.


<PAGE>   2

PART I. INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

     ITEM 1. PLAN INFORMATION.

     The information required by Part I is included in documents sent or given
to participants in the 1998 Stock Incentive Plan, the 2000 Outside Director
Stock Option Plan and the 2000 Employee Stock Purchase Plan of The Medicines
Company pursuant to Rule 428(b)(1) of the Securities Act of 1933, as amended
(the "Securities Act").

PART II. INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

     ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.

     The registrant is subject to the informational and reporting requirements
of Sections 13(a), 14, and 15(d) of the Securities Exchange Act of 1934, as
amended (the "Exchange Act"), and in accordance therewith files reports, proxy
statements and other information with the Securities and Exchange Commission
(the "Commission"). The following documents, which are on file with the
Commission, are incorporated in this registration statement by reference:

     (a) The registrant's latest annual report filed pursuant to Section 13(a)
or 15(d) of the Exchange Act or the latest prospectus filed pursuant to Rule
424(b) under the Securities Act that contains audited financial statements for
the registrant's latest fiscal year for which such statements have been filed.

     (b) All other reports filed pursuant to Section 13(a) or 15(d) of the
Exchange Act since the end of the fiscal year covered by the document referred
to in (a) above.

     (c) The description of the Common Stock of the registrant, $0.01 par value
per share (the "Common Stock"), contained in the registrant's registration
statement on Form 8-A and filed under the Exchange Act, including any amendment
or report filed for the purpose of updating such description.

     All documents subsequently filed by the registrant pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a
post-effective amendment which indicates that all shares of Common Stock offered
hereby have been sold or which deregisters all shares of Common Stock then
remaining unsold, shall be deemed to be incorporated by reference herein and to
be part hereof from the date of the filing of such documents. Any statement
contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for the purposes of this
registration statement to the extent that a statement contained herein or in any
other subsequently filed document which also is or is deemed to be incorporated
by reference herein modifies or supersedes such statement. Any statement so
modified or superseded shall not be deemed, except as so modified or superseded,
to constitute a part of this registration statement.

     ITEM 4. DESCRIPTION OF SECURITIES.

     Not applicable.



                                      -2-
<PAGE>   3


     ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.

     Hale and Dorr LLP has opined as to the legality of the securities being
offered by this registration statement. Partners of Hale and Dorr LLP
beneficially own an aggregate of 23,634 shares of Common Stock and a warrant to
purchase an aggregate of 1,554 shares of Common Stock.

     ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

     The Registrant's Third Amended and Restated Certificate of Incorporation,
as amended to date (the "Charter") provides that, except to the extent
prohibited by the Delaware General Corporation Law (the "DGCL"), the
Registrant's directors shall not be personally liable to the Registrant or its
stockholders for monetary damages for any breach of fiduciary duty as directors
of the Registrant. Under the DGCL, the directors have a fiduciary duty to the
Registrant which is not eliminated by this provision of the Charter and, in
appropriate circumstances, equitable remedies such as injunctive or other forms
of nonmonetary relief will remain available. In addition, each director will
continue to be subject to liability under the DGCL for breach of the director's
duty of loyalty to the Registrant, for acts or omissions which are found by a
court of competent jurisdiction to be not in good faith or involving intentional
misconduct, for knowing violations of law, for actions leading to improper
personal benefit to the director, and for payment of dividends or approval of
stock repurchases or redemptions that are prohibited by DGCL. This provision
also does not affect the directors' responsibilities under any other laws, such
as the Federal securities laws or state or Federal environmental laws. The
Registrant has obtained liability insurance for its officers and directors.

     Section 145 of the DGCL empowers any corporation to indemnify its directors
and officers and to purchase insurance with respect to liability arising out of
their capacity or status as directors and officers, provided that this provision
shall not eliminate or limit the liability of a director: (i) for any breach of
the director's duty of loyalty to the corporation or its stockholders, (ii) for
acts or omissions not in good faith or which involve intentional misconduct or a
knowing violation of law, (iii) arising under Section 174 of the DGCL, or (iv)
for any transaction from which the director derived an improper personal
benefit. The DGCL provides further that the indemnification permitted thereunder
shall not be deemed exclusive of any other rights to which the directors and
officers may be entitled under the corporation's bylaws, any agreement, a vote
of stockholders or otherwise. The Charter eliminates the personal liability of
directors to the fullest extent permitted by Section 102(b)(7) of the DGCL and
provides that the Registrant shall fully indemnify any person who was or is a
party or is threatened to be made a party to any threatened, pending or
completed action, suit or proceeding (whether civil, criminal, administrative or
investigative) by reason of the fact that such person is or was a director or
officer of the Registrant, or is or was serving at the request of the Registrant
as a director or officer of another corporation, partnership, joint venture,
trust, employee benefit plan or other enterprise, against expenses (including
attorney's fees), judgments, fines and amounts paid in settlement actually and
reasonably incurred by such person in connection with such action, suit or
proceeding.

     At present, there is no pending litigation or proceeding involving any
director, officer, employee or agent as to which indemnification will be
required or permitted under the Charter. The Registrant is not aware of any
threatened litigation or proceeding that may result in a claim for such
indemnification.




                                      -3-
<PAGE>   4

     Article EIGHTH of the Registrant's Charter provides that no director of the
registrant shall be personally liable for any monetary damages for any breach of
fiduciary duty as a director, except to the extent that the Delaware General
Corporation Law statute prohibits the elimination or limitation of liability of
directors for breach of fiduciary duty.

     Article NINTH of the Registrant's Charter provides that a director or
officer of the registrant (a) shall be indemnified by the registrant against all
expenses (including attorneys' fees), judgments, fines and amounts paid in
settlement incurred in connection with any litigation or other legal proceeding
(other than an action by or in the right of the registrant) brought against him
by virtue of his position as a director or officer of the registrant if he acted
in good faith and in a manner he reasonably believed to be in, or not opposed
to, the best interests of the registrant, and, with respect to any criminal
action or proceeding, had no reasonable cause to believe his conduct was
unlawful and (b) shall be indemnified by the registrant against all expenses
(including attorneys' fees) and amounts paid in settlement incurred in
connection with any action by or in the right of the registrant brought against
him by virtue of his position as a director or officer of the registrant if he
acted in good faith and in a manner he reasonably believed to be in, or not
opposed to, the best interests of the registrant, except that no indemnification
shall be made with respect to any matter as to which such person shall have been
adjudged to be liable to the registrant, unless a court determines that, despite
such adjudication but in view of all of the circumstances, he is entitled to
indemnification of such expenses. Notwithstanding the foregoing, to the extent
that a director or officer has been successful, on the merits or otherwise,
including, without limitation, the dismissal of an action without prejudice, he
is required to be indemnified by the registrant against all expenses (including
attorneys' fees) incurred in connection therewith. Expenses shall be advanced to
a director or officer at his request, provided that he undertakes to repay the
amount advanced if it is ultimately determined that he is not entitled to
indemnification for such expenses.

     Indemnification is required to be made unless the registrant determines
that the applicable standard of conduct required for indemnification has not
been met. In the event of a determination by the registrant that the director or
officer did not meet the applicable standard of conduct required for
indemnification, or if the registrant fails to make an indemnification payment
within 60 days after such payment is claimed by such person, such person is
permitted to petition the court to make an independent determination as to
whether such person is entitled to indemnification. As a condition precedent to
the right of indemnification, the director or officer must give the registrant
notice of the action for which indemnity is sought and the registrant has the
right to participate in such action or assume the defense thereof.

     Article NINTH of the Registrant's Charter further provides that the
indemnification provided therein is not exclusive, and provides that in the
event that the Delaware General Corporation Law statute is amended to expand the
indemnification permitted to directors or officers the registrant must indemnify
those persons to the full extent permitted by such law as so amended.

     ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.

     Not applicable.

     ITEM 8. EXHIBITS.

     The Exhibit Index immediately preceding the exhibits is incorporated herein
by reference.





                                      -4-
<PAGE>   5

     ITEM 9. UNDERTAKINGS.

     1. The undersigned registrant hereby undertakes:

          (1) To file, during any period in which offers or sales are being
     made, a post-effective amendment to this registration statement:

              (i) To include any prospectus required by Section 10(a)(3) of the
     Securities Act;

              (ii) To reflect in the prospectus any facts or events arising
     after the effective date of the registration statement (or the most recent
     post-effective amendment thereof) which, individually or in the aggregate,
     represent a fundamental change in the information set forth in the
     registration statement. Notwithstanding the foregoing, any increase or
     decrease in volume of securities offered (if the total dollar value of
     securities offered would not exceed that which was registered) and any
     deviation from the low or high end of the estimated maximum offering range
     may be reflected in the form of prospectus filed with the Commission
     pursuant to Rule 424(b) if, in the aggregate, the changes in volume and
     price represent no more than 20 percent change in the maximum aggregate
     offering price set forth in the "Calculation of Registration Fee" table in
     the effective registration statement; and

              (iii) To include any material information with respect to the
     plan of distribution not previously disclosed in the registration statement
     or any material change to such information in the registration statement;

     provided, however, that paragraphs (i) and (ii) do not apply if the
     information required to be included in a post-effective amendment by those
     paragraphs is contained in periodic reports filed with or furnished to the
     Commission by the registrant pursuant to Section 13 or Section 15(d) of the
     Exchange Act that are incorporated by reference in the registration
     statement.

          (2) That, for the purpose of determining any liability under the
     Securities Act, each such post-effective amendment shall be deemed to be a
     new registration statement relating to the securities offered therein, and
     the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

     2. The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act that is incorporated by reference in the registration statement
shall be deemed to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time shall be
deemed to be the initial bona fide offering thereof.

     3. Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions, or otherwise, the registrant
has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the


                                      -5-

<PAGE>   6

Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.

                    [Rest of Page Intentionally Left Blank.]



























                                      -6-

<PAGE>   7


                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in Cambridge, Massachusetts, on this 30th day of August, 2000.

                                        THE MEDICINES COMPANY

                                        By: /s/ Peyton J. Marshall
                                           ----------------------------
                                           Peyton J. Marshall
                                           Chief Financial Officer

                        POWER OF ATTORNEY AND SIGNATURES

     We, the undersigned officers and directors of The Medicines Company, Inc.,
hereby severally constitute and appoint Clive A. Meanwell and Peyton J.
Marshall, and each of them singly, our true and lawful attorneys with full power
to them, and each of them singly, to sign for us and in our names in the
capacities indicated below, the Registration Statement on Form S-8 filed
herewith and any and all subsequent amendments to said Registration Statement,
and generally to do all such things in our names and on our behalf in our
capacities as officers and directors to enable The Medicines Company, Inc. to
comply with the provisions of the Securities Act of 1933 and all requirements of
the Securities and Exchange Commission, hereby ratifying and confirming our
signatures as they may be signed by our said attorneys, or any of them, to said
Registration Statement and any and all amendments thereto.

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated.

      SIGNATURE                    TITLE                              DATE


/s/ Clive A. Meanwell     President, Chief Executive             August 30, 2000
-----------------------   Officer and Director (Principal
Clive A. Meanwell         Executive Officer)


/s/ Peyton J. Marshall    Chief Financial Officer                August 30, 2000
-----------------------   (Principal Financial and
Peyton J. Marshall        Accounting Officer)


                          Director                               August __, 2000
-----------------------
Dennis B. Gillings

                          Director                               August __, 2000
-----------------------
Anders D. Hove



                                      -7-
<PAGE>   8

------------------------  Director                               August __, 2000
M. Fazle Husain


/s/ T. Scott Johnson      Director                               August 30, 2000
------------------------
T. Scott Johnson


/s/ Armin M. Kessler      Director                               August 30, 2000
------------------------
Armin M. Kessler


/s/ James E. Thomas       Director                               August 30, 2000
------------------------
James E. Thomas


/s/ Robert Yedid          Director                               August __, 2000
------------------------
Robert Yedid


                          Director                               August __, 2000
------------------------
Leonard Bell





                                      -8-


<PAGE>   9



                                INDEX TO EXHIBITS

NUMBER    DESCRIPTION
3.1(1)    Third Amended and Restated Certificate of Incorporation of the
          Registrant

3.2(1)    Amended and Restated By-Laws of the Registrant

4.1(1)    Specimen stock certificate of common stock of the Registrant

5.1       Opinion of Hale and Dorr LLP, counsel to the Registrant

23.1      Consent of Hale and Dorr LLP
          (included in Exhibit 5.1)

23.2      Consent of Ernst & Young LLP

24.1      Power of attorney (included in the signature pages of this
          registration statement)

------------

(1)  Previously filed with the Securities and Exchange Commission as an Exhibit
     to the Registrant's Registration Statement on Form S-1, as amended (File
     No. 333-37404) and incorporated herein by reference.






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