ORASURE TECHNOLOGIES INC
S-8, EX-5, 2000-11-20
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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                                    Exhibit 5
                                    ---------
                                November 17, 2000

OraSure Technologies, Inc.
8505 S.W. Creekside Place
Beaverton, Oregon  97008

         Subject: OraSure Technologies, Inc. Registration Statement on Form S-8

Ladies and Gentlemen:

         Reference   is  made  to  the   registration   statement  on  Form  S-8
("Registration Statement") to be filed by OraSure Technologies, Inc., a Delaware
corporation (the "Company"), with the Securities and Exchange Commission for the
purpose of registering  under the Securities Act of 1933, as amended,  6,185,400
shares (the  "Registered  Shares") of the Company's  common stock,  $.000001 per
share ("Common Stock"), to be issued in connection with the Company's 2000 Stock
Award  Plan  and  Employee   Incentive  and  Non-Qualified   Stock  Option  Plan
(collectively,  the  "Plans"),  together  with options and other rights  related
thereto.

         We have examined originals or copies, certified or otherwise identified
to  our  satisfaction,   of  such  corporate  records,  certificates  of  public
officials,  and other  documents  as we have deemed  necessary  or relevant as a
basis for the opinion set forth herein.

         Based on the foregoing,  it is our opinion that the Registered  Shares,
when sold and  delivered by the Company upon  exercise of options or pursuant to
other rights duly granted under the Plans against payment for such shares to the
extent and in the manner required by the Plans,  will be validly  issued,  fully
paid and non-assessable.

         We consent to the use of this opinion in the Registration Statement and
in any amendments thereof.

                                            Very truly yours,

                                            /s/  MILLER NASH LLP



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