<TABLE> <S> <C>
<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from CombiMatrix
balances at December 31, 1999 and nine-month period ended September 30, 2000 and
the nine months ended September 30, 2000 and is qualified in its entirety by
reference to such financial statements.
</LEGEND>
<MULTIPLIER> 1,000
<S> <C> <C>
<PERIOD-TYPE> 12-MOS 9-MOS
<FISCAL-YEAR-END> DEC-31-1999 DEC-31-2000
<PERIOD-START> JAN-01-1999 JAN-01-2000
<PERIOD-END> DEC-31-1999 SEP-30-2000
<CASH> 1,459 8,701
<SECURITIES> 0 40,863
<RECEIVABLES> 28 37
<ALLOWANCES> 0 0
<INVENTORY> 0 160
<CURRENT-ASSETS> 1,493 50,251
<PP&E> 319 1,193
<DEPRECIATION> 117 251
<TOTAL-ASSETS> 1,726 51,225
<CURRENT-LIABILITIES> 179 1,204
<BONDS> 0 0
0 0
0 0
<COMMON> 11 18
<OTHER-SE> 1,536 50,003
<TOTAL-LIABILITY-AND-EQUITY> 1,726 51,225
<SALES> 143 17
<TOTAL-REVENUES> 143 17
<CGS> 0 0
<TOTAL-COSTS> 2,493 8,219
<OTHER-EXPENSES> 0 0
<LOSS-PROVISION> 0 0
<INTEREST-EXPENSE> 213 0
<INCOME-PRETAX> (2,520) (7,357)
<INCOME-TAX> 0 0
<INCOME-CONTINUING> (2,520) (7,357)
<DISCONTINUED> 0 0
<EXTRAORDINARY> 0 0
<CHANGES> 0 0
<NET-INCOME> (2,520) (7,357)
<EPS-BASIC> (0.29) (0.52)
<EPS-DILUTED> (0.29) (0.52)
</TABLE>