BIOSPHERICS INC
8-K, 1997-12-18
ENGINEERING, ACCOUNTING, RESEARCH, MANAGEMENT
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549
                                           
                                    FORM 8-K
                                           
     Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934
                                           
Date of Report (Date of earliest event reported):  December 12, 1997

                 BIOSPHERICS-Registered Trademark- INCORPORATED
                                           
- -------------------------------------------------------------------------------
             (Exact name of registrant as specified in its charter)

       Delaware                          0-5576                 52-0849320
- --------------------------------  -----------------------    ------------------
  (Name or other jurisdiction     (Commission File Number)     (IRS Employer
of incorporation or organization)                            Identification No.)

12051 Indian Creek Court, Beltsville, Maryland                    20705
- ----------------------------------------------              -------------------
  (Address of principal executive offices)                      (Zip Code)

Registrant's telephone number, including area code:        301-419-3900  
                                                    ---------------------------
Item 5.  Other Events.

    Biospherics Incorporated announced the completion of a $3 million private 
offering of units consisting of shares of its common stock and warrants. 
Wharton Capital, a New York-based financial consulting firm, helped 
facilitate the transaction and received a cash fee of $150,000 and 40,000 
units (each unit consisting of two shares of common stock and one warrant 
exercisable at $4 per share).  A copy of the definitive agreements between 
the Registrant and the Investor and the press release issued by Biospherics 
Incorporated are attached hereto as Exhibits to this Form 8-K.

Item 7.  Financial Statements and Exhibits

    (c)  Exhibits

    (10.1) Securities Purchase Agreement, dated as of December 12, 1997, 
           by and between Biospherics Incorporated and RGC International 
           Investors, LDC (filed herewith).

    (10.2) Exhibit A-1 to Securities Purchase Agreement - Form of Warrants  
           to be issued by Registrant (filed herewith).

    (10.3) Exhibit A-2 to Securities Purchase Agreement - Form of Warrants  
           to be issued by Registrant (filed herewith).

<PAGE>

    (10.4) Exhibit B to Securities Purchase Agreement - Registration Rights 
           Agreement, dated as of December 12, 1997, by and among Biospherics
           Incorporated and RGC International Investors, LDC (filed herewith).

    (99)   Press Release dated December 17, 1997.

                                 SIGNATURES
                                       
    Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned hereunto duly authorized.

Date:  December 18, 1997

                                       Biospherics Incorporated 
                                       ---------------------------------
                                       (Registrant)


                                       /s/ Jeffrey W. Church    
                                       ---------------------------------
                                       (Signature)

                                       Name:  Jeffrey W. Church
                                       Title: Executive Vice President and
                                               Chief Financial Officer


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                                                                  Exhibit (10.1)

                            SECURITIES PURCHASE AGREEMENT
                                           


    This SECURITIES PURCHASE AGREEMENT ("Agreement") is entered into as of 
December 12, 1997, by and between Biospherics Incorporated, a Delaware 
corporation (the "Company"), with headquarters located at 12051 Indian Creek 
Court, Beltsville, Maryland, and the Purchaser (the "Purchaser") set forth on 
the execution pages hereof, with regard to the following:

                                       RECITALS
                                           
    A.   The Company and Purchaser are executing and delivering this 
Agreement in reliance upon the exemption from securities registration 
afforded by the provisions of Regulation D ("Regulation D"), as promulgated 
by the United States Securities and Exchange Commission (the "SEC") under the 
Securities Act of 1933, as amended (the "Securities Act").

    B.   Purchaser desires to purchase, upon the terms and conditions stated 
in this Agreement, (i) shares of the Company's Common Stock, par value $.005 
per share (the "Common Stock") and (ii) warrants to purchase shares of Common 
Stock in the forms attached hereto as Exhibits A-1 and A-2.  The shares of 
Common Stock being purchased hereunder are referred to herein as the "Common 
Shares". The warrants being purchased hereunder are referred to herein as the 
"Warrants". The shares of Common Stock issuable upon the exercise of or 
otherwise pursuant to the Warrants are referred to herein as the "Warrant 
Shares".  The Common Shares, Warrants and Warrant Shares are collectively 
referred to herein as the "Securities."

    C.   Contemporaneous with the execution and delivery of this Agreement, 
the parties hereto are executing and delivering a Registration Rights 
Agreement in the form attached hereto as Exhibit B (the "Registration Rights 
Agreement"), pursuant to which the Company has agreed to provide certain 
registration rights under the Securities Act, the rules and regulations 
promulgated thereunder and applicable state securities laws.

                                      AGREEMENTS
                                           
    NOW, THEREFORE, in consideration of their respective promises contained 
herein and other good and valuable consideration, the receipt and sufficiency 
of which are hereby acknowledged, the Company and Purchaser hereby agree as 
follows:

                                      ARTICLE I
                           PURCHASE AND SALE OF SECURITIES
                                           
    1.1  Purchase of Common Stock and Warrants.  Subject to the terms and 
conditions of this Agreement, the Company shall issue and sell, and Purchaser 
shall purchase, Common Stock and Warrants as further contemplated hereby.  
The purchase price for a unit consisting of two (2) shares of Common Stock 
and two (2) Warrants, each Warrant to purchase one (1) share of 

                                       1

<PAGE>

Common Stock (subject to adjustment as provided in the Warrant) shall be 
$8.00. Purchaser shall purchase the number of shares of Common Stock set 
forth on the signature page executed by Purchaser.  In addition, Purchaser 
shall purchase Warrants to purchase the number of shares of Common Stock 
(subject to adjustment as provided in the Warrants) set forth on the 
signature page executed by Purchaser.

    1.2  Form of Payment.  Purchaser shall pay the aggregate Purchase Price 
for the Common Shares and Warrants being purchased by Purchaser by wire 
transfer to the Company, in accordance with the Company's written wiring 
instructions, against delivery of duly executed Warrants and stock 
certificates for the Common Shares, and the Company shall deliver such Common 
Shares and Warrants against delivery of such aggregate Purchase Price.

    1.3  Closing Date.  Subject to the satisfaction (or waiver) of the 
conditions set forth in Articles VI and VII below, the closing (the 
"Closing") of the issuance, sale and purchase of the Securities pursuant to 
this Agreement shall occur at 10:00 a.m. on December 12, 1997 (the "Closing 
Date"), at the offices of Ballard, Spahr, Andrews & Ingersoll, 1735 Market 
Street, 51st Floor, Philadelphia, PA 19103-7599.

                                      ARTICLE II
                      PURCHASER'S REPRESENTATIONS AND WARRANTIES
                                           
    Purchaser represents and warrants, solely with respect to itself and its 
purchase hereunder.  No Purchaser makes any other representations or 
warranties, express or implied, to the Company in connection with the 
transactions contemplated hereby and any and all prior representations and 
warranties, if any, which may have been made by Purchaser to the Company in 
connection with the transactions contemplated hereby shall be deemed to have 
been merged in this Agreement and any such prior representations and 
warranties, if any, shall not survive the execution and delivery of this 
Agreement.

    2.1  Investment Purpose.  Purchaser is purchasing the Common Shares and 
Warrants (collectively, the "Purchased Securities") for Purchaser's own 
account for investment only and not with a present view toward or in 
connection with the public sale or distribution thereof.  Purchaser will not 
resell the Purchased Securities or any securities which may be issued upon 
exercise of the Warrants except pursuant to an effective registration 
statement filed under the Securities Act or sales that are exempt from the 
registration requirements of the Securities Act and/or sales registered under 
the Securities Act.  Purchaser understands that Purchaser must bear the 
economic risk of this investment indefinitely, unless the Securities are 
registered pursuant to the Securities Act and any applicable state securities 
laws or an exemption from such Securities Act other than as contemplated by 
the Registration Rights Agreement. By making the representations in this 
Section 2.1, the Purchaser does not agree to hold the Securities for any 
minimum or other specific term and reserves the right to dispose of the 
Securities at any time in accordance with or pursuant to a registration 
statement or an exemption from registration under the Securities Act or 
applicable state securities laws.

    2.2  Accredited Investor Status.  Purchaser is an "accredited investor" 
as that term is defined in Rule 501(a) of Regulation D.

                                          2

<PAGE>

    2.3. Reliance on Exemptions.  Purchaser understands that the Purchased 
Securities are being offered and sold to the Purchaser in reliance upon 
specific exemptions from the registration requirements of the United States 
federal and state securities laws and that the Company is relying upon the 
truth and accuracy of, and Purchaser's compliance with, the representations, 
warranties, agreements, acknowledgments and understanding of Purchaser set 
forth herein in order to determine the availability of such exemptions and 
the eligibility of Purchaser to acquire the Purchased Securities.

    2.4  Information.  Purchaser and its counsel have been furnished all 
materials relating to the business, finances and operations of the Company 
and materials relating to the offer and sale of the Purchased Securities 
which have been specifically requested by Purchaser.  Purchaser has been 
afforded the opportunity to ask questions of the Company and has received 
what Purchaser believes to be complete and satisfactory answers to any such 
inquiries.  Neither such inquiries nor any other due diligence investigation 
conducted by Purchaser or any of its representations shall modify, amend or 
affect Purchaser's right to rely on the Company's representations and 
warranties contained in Article III or the Officer's Certificate delivered 
pursuant to Section 3.3.  Purchaser understands that Purchaser's investment 
in the Securities involves a high degree of risk.

    2.5  Governmental Review.  Purchaser understands that no United States 
federal or state agency or any other government agency has passed upon or 
made any recommendation or endorsement of the Securities or an investment 
therein.

    2.6  Transfer or Resale.  Purchaser understands that (i) except as 
provided in the Registration Rights Agreement, the Securities have not been 
and are not being registered under the Securities Act or any state securities 
laws, and may not be transferred unless subsequently registered thereunder, 
an exemption from such registration is available (which exemption the Company 
expressly agrees may be established as contemplated in clauses (b) and (c) of 
Section 5.1 hereof) or such Securities are sold or transferred to an 
"affiliate" (as defined in Rule 144 under the Securities Act (or a successor 
rule) ("Rule 144")); (ii) any sale of such Securities made in reliance on Rule 
144 may be made only in accordance with the terms of said Rule and further, 
if said Rule is not applicable, any resale of such Securities without 
registration under the Securities Act under circumstances in which the seller 
may be deemed to be an underwriter (as that term is defined in the Securities 
Act) may require compliance with some other exemption under the Securities 
Act or the rules and regulations of the SEC thereunder; and (iii) neither the 
Company nor any other person is under any obligation to register such 
Securities under the Securities Act or any state securities laws or to comply 
with the terms and conditions of any exemption thereunder (in each case, 
other than pursuant to this Agreement or the Registration Rights Agreement).

    2.7  Legends.  Purchaser understands that, subject to Article V hereof, 
the certificates for the Common Shares and Warrant Shares, and until such 
time as the Common Shares and Warrant Shares have been registered under the 
Securities Act as contemplated by the Registration Rights Agreement or 
otherwise may be sold by Purchaser pursuant to Rule 144, the certificates for 
the Common Shares and Warrant Shares will be a restrictive legend (the 
"Legend") in the following form:

                                          3

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    THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN
    REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR THE
    SECURITIES LAWS OF ANY STATE OF THE UNITED STATES.  THE SECURITIES
    REPRESENTED HEREBY MAY NOT BE OFFERED OR SOLD OR OTHERWISE TRANSFERRED
    IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT FOR THE
    SECURITIES UNDER APPLICABLE SECURITIES LAWS OR UNLESS OFFERED, SOLD OR
    TRANSFERRED PURSUANT TO AN AVAILABLE EXEMPTION FROM THE REGISTRATION
    REQUIRMETNS OF THOSE LAWS.

    2.8  Authorization:  Enforcement.  This Agreement and the Registration 
Rights Agreement have been duly and validly authorized, executed and 
delivered on behalf of Purchaser and are valid and binding agreements of 
Purchaser enforceable against Purchaser in accordance with their terms.

    2.9  Residency.  Purchaser is a resident of the jurisdiction set forth 
under Purchaser's name on the signature page hereto executed by Purchaser.

    2.10 Organization.  Purchaser is duly organized, validity existing and in 
good standing under the laws of the jurisdiction in which it is formed, and has 
the requisite power and authority to own its properties and to carry on its 
business as now being conducted.

                                     ARTICLE III
                    REPRESENTATIONS AND WARRANTIES OF THE COMPANY
                                           
    The Company represents and warrants to the Purchaser that:

    3.1  Organization and Qualification.  The Company and each of its 
subsidiaries is a corporation duly organized, validity existing and in good 
standing under the laws of the jurisdiction in which it is incorporated, and 
has the requisite corporate power and authority to own its properties and to 
carry on its business as now being conducted.  The Company and each of its 
subsidiaries is duly qualified as a foreign corporation to do business and is 
in good standing in every jurisdiction where the failure to so qualify would 
have a Material Adverse Effect.  "Material Adverse Effect"  means any 
material adverse effect on either (i) the business, operations, properties, 
financial condition, operating results or prospects of the Company and its 
subsidiaries, taken as a whole on a consolidated basis or (ii) the 
transactions contemplated hereby.

    3.2  Authorization:  Enforcement.  (a) The Company has the requisite 
corporate power and authority to enter into and perform this Agreement, the 
Warrants and the Registration Rights Agreement, and to issue and sell, 
perform its obligations with respect to, the Purchased Securities in 
accordance with the terms hereof and to issue the Warrant Shares in 
accordance with the terms and conditions of the Warrants; (b) the execution, 
delivery and performance of this Agreement, the Warrants and the Registration 
Rights Agreement by the Company and the consummation by it of the 
transactions contemplated hereby and thereby (including without limitation 
the issuance of the Purchased Securities and the reservation for issuance and 
issuance of the Warrant Shares) 

                                          4

<PAGE>

have been duly authorized by all necessary corporate action and, except as 
set forth on Schedule 3.2 hereof, no further consent or authorization of the 
Company, its board of directors, or its stockholders or any other person, 
body or agency is required with respect to any of the transactions 
contemplated hereby or thereby (whether under rules of NASDAQ National Market 
System ("NASDAQ"), the National Association of Securities Dealers or 
otherwise); (c) this Agreement, the Registration Rights Agreement and the 
Purchased Securities have been duly executed and delivered by the Company; 
and (d) this Agreement, the Registration Rights Agreement and the Purchased 
Securities constitute legal, valid and binding obligations of the Company 
enforceable against the Company in accordance with their terms.

    3.3  Capitalization.  The capitalization of the Company as of the date 
hereof, including the authorized capital stock, the number of shares issued 
and outstanding, the number of shares reserved for issuance pursuant to the 
Company's stock option plans, the number of shares reserved for issuance 
pursuant to securities (other than the Warrants) exercisable for, or 
convertible into or exchangeable for any shares of Common Stock and the 
number of shares to be initially reserved for issuance upon exercise of the 
Warrants is set forth on Schedule 3.3.  All of such outstanding shares of 
capital stock have been, or upon issuance will be, validly issued, fully paid 
and nonassessable.  No shares of capital stock of the Company (including the 
Common Shares and the Warrant Shares) are subject to preemptive rights or any 
other similar rights of the stockholders of the Company or any liens or 
encumbrances.  Except as disclosed in Schedule 3.3, as of the date of this 
Agreement, (i) there are no outstanding options, warrants, scrip, rights to 
subscribe for, calls or commitments of any character whatsoever relating to, 
or securities or rights convertible into or exercisable or exchangeable for, 
any shares of capital stock of the Company or any of its subsidiaries or 
contracts, commitments, understandings or arrangements by which the Company 
or any of its subsidiaries is or may become bound to issue additional shares 
of capital stock of the Company or any of its subsidiaries, (ii) there are no 
agreements or arrangements under which the Company or any of its subsidiaries 
is obligated to register the sale of any of its or their securities under the 
Securities Act (except the Registration Rights Agreement), and (iii) there 
are no anti-dilutive or price adjustment provisions contained in any security 
issued by the Company (or any agreement providing rights to security holders) 
that will be triggered by the issuance of the Purchased Securities or Warrant 
Shares.  The Company has furnished to Purchaser true and correct copies of 
the Company's Certificate of Incorporation as currently in effect 
("Certificate of Incorporation"), and the Company's By-laws as currently in 
effect (the "By-laws").  The Company has set forth on Schedule 3.3 all 
instruments and agreements (other than the Certificate of Incorporation and 
By-laws) governing securities convertible into or exercisable for Common 
Stock of the Company (and the Company shall provide to Purchaser copies 
thereof upon the request of Purchaser).  The Company shall provide Purchaser 
with a written update of this representation signed by the Company's Chief 
Executive Officer on behalf of the Company as of the date of the Closing.

    3.4  Issuance of Shares.  The Common Shares and Warrant Shares are duly 
authorized and reserved for issuance, and, upon consummation of the purchase 
contemplated hereby (with respect to the Common Shares) and exercise of the 
Warrants in accordance with the terms thereof (with respect to the Warrant 
Shares), will be validly issued, fully paid and non-assessable, and 

                                          5

<PAGE>

free from all taxes, liens, claims and encumbrances and will not be subject 
to the preemptive rights or other similar rights of stockholders of the 
Company. The Common Shares are duly authorized and reserved for issuance, and 
are validly issued, fully paid and nonassessable, and free from all taxes, 
liens claims and encumbrances and are not and will not be subject to 
preemptive rights or other similar rights of stockholders of the Company.  
Accordingly, no further corporate authorization or approval is required under 
the rules of the NASDAQ with respect to the transaction contemplated by this 
Agreement, including, without limitation, the issuance of the Warrant Shares 
and the inclusion thereof on the NASDAQ.  The Company understands and 
acknowledges the potentially dilutive effect to the Common Stock upon the 
issuance of the Common Shares and, upon exercise of the Warrants, the Warrant 
Shares.  The Company further acknowledges that its obligation to issue the 
Common Shares and the Warrant Shares upon the exercise of the Warrants in 
accordance with this Agreement and the Warrants is absolute and unconditional 
regardless of the dilutive effect that such issuance may have on the 
ownership interests of other stockholders of the Company.

    3.5  No Conflicts.  The execution, delivery and performance of this 
Agreement, the Warrants and the Registration Rights Agreement by the Company, 
and the consummation by the Company of transactions contemplated hereby and 
thereby (including, without limitation, the issuance and reservation for 
issuance, as applicable, of the Common Shares and Warrant Shares) will not 
(a) result in a violation of the Certificate of Incorporation or By-laws, (b) 
violate or conflict with, or constitute a default (or an event which with 
notice or lapse of time or both would become a default) under, or give to 
others any rights of termination, amendment, acceleration, or cancellation 
of, any agreement, indenture or instrument to which the Company or any of its 
subsidiaries is a party (except for such conflicts, defaults, terminations, 
amendments, accelerations, and cancellations as would not, individually or in 
the aggregate, have a Material Adverse Effect), or (c) result in a violation 
of any law, rule, regulation, order, judgment or decree to the Company or any 
of its subsidiaries, or by which any property or asset of the Company or any 
of its subsidiaries, is bound or affected.  Neither the Company nor any of 
its subsidiaries is in violation of its Certificate of Incorporation, By-laws 
or other organizational documents, and neither the Company nor any of its 
subsidiaries is in default (and no event has occurred which, with notice or 
lapse of time or both, would put the Company or any of its subsidiaries in 
default) under, nor has there occurred any event giving others (with notice 
or lapse of time or both) any rights of termination, amendment, acceleration 
or cancellation of, any agreement, indenture or instrument to which the 
Company or any of its subsidiaries is a party, except for possible defaults 
or rights as would not, individually or in the aggregate, have a Material 
Adverse Effect. The business of the Company and its subsidiaries are not 
being conducted, and shall not be conducted so long as Purchaser owns any of 
the Securities, in violation of any law, ordinance, rule, regulation, order, 
judgment or decree of any governmental entity, court or arbitration tribunal 
except for possible violations the sanctions for which either singly or in 
the aggregate would not have a Material Adverse Effect.  Except as set forth 
on Schedule 3.5, the Company is not required to obtain any consent, 
authorization or order of, or make any filing or registration with, any court 
or governmental agency or any regulatory or self-regulatory agency in order 
for it to execute, deliver or perform any of its obligations under this 
Agreement, the Warrants or the Registration Rights Agreement or to perform 
its obligations in accordance with the terms hereof or thereof.  The Company 
is not in violation of the listing requirements of NASDAQ and does not 
reasonably anticipate that the Common Stock will be delisted by NASDAQ for 
the foreseeable future.  The Company and its subsidiaries are unaware of any 
facts which might give rise to any of the foregoing.

                                          6

<PAGE>

    3.6  Registration and SEC Documents.  The Common Stock is registered 
under Section 12 of the Securities Exchange Act of 1934, as amended (the 
"Exchange Act") and has been so registered since 1969.  Except as disclosed 
in Schedule 3.6, since January 1, 1995, the Company has timely filed all 
reports, schedules, forms, statements and other documents required to be 
filed by it with the SEC pursuant to the reporting requirements of the 
Exchange Act (all of the foregoing filed after December 31, 1993 and all 
exhibits included therein and financial statements and schedules thereto and 
documents incorporated by reference therein, being referred to herein as the 
"SEC Documents").  The Company has delivered to Purchaser true and complete 
copies of the SEC Documents, except for exhibits, schedules and incorporated 
documents (the SEC documents filed prior to the date hereof being the "Filed 
SEC Documents").  As of their respective dates, the SEC Documents complied in 
all material respects with the requirements of the Exchange Act and the rules 
and regulations of the SEC promulgated thereunder applicable to the SEC 
Documents, and none of the SEC Documents, at the time they were filed with 
the SEC, contained any untrue statements of a material fact or omitted to 
state a material fact required to be stated therein or necessary in order to 
make the statements therein, in light of the circumstances under which they 
were made, not misleading.  None of the statements made in any such SEC 
Documents is required to be updated or amended under applicable law.  The 
financial statements of the Company included in the SEC Documents have been 
prepared in accordance with U.S. generally accepted accounting principles, 
consistently applied, and the rules and regulations of the SEC during the 
periods involved (except (i) as may be otherwise indicated in such financial 
statements or the notes thereto, or (ii) in the case of unaudited interim 
statements, to the extent they do not include footnotes or are condensed or 
summary statements) and present accurately and completely the consolidated 
financial position of the Company and its consolidated subsidiaries as of the 
dates thereof and the consolidated results of their operations and cash flows 
for the periods then ended (subject, in the case of unaudited statements, to 
normal, immaterial year-end audit adjustments).  Except as set forth in the 
financial statements of the Company included in the Filed SEC Documents, the 
Company has no liabilities, contingent or otherwise, other than (i) 
liabilities incurred subsequent to the date of such financial statements in 
the ordinary course of business consistent with the past practice and (ii) 
obligations under contracts and commitments incurred in the ordinary course 
of business and not required under generally accepted accounting principles 
to be reflected in such financial statements, in each case of clause (i) and 
(ii) next above which, individually and in the aggregate, are not material to 
the financial condition, business, operations, properties, operating results 
or prospects of the Company and its subsidiaries taken on a whole.  The Filed 
SEC Documents contain a complete and accurate list of all material 
undischarged written or oral contracts, agreements, leases or other 
instruments to which the Company or any subsidiary is a party or by which the 
Company or any subsidiary is bound or to which any of the properties or 
assets of the Company or any subsidiary is subject (each a "Contract").  None 
of the Company, its subsidiaries or, to the best knowledge of the Company, 
any of the other parties thereto, is in breach or violation of any Contract, 
which breach or violation would have a Material Adverse Effect.  No event, 
occurrence or condition exists which, with the lapse of time, the giving of 
notice, or both, or the happening of any further event or condition, would 
become a breach or default by the Company or its subsidiaries or, to the 
Company's knowledge, by any other party under any Contract which breach or 
default would have a Material Adverse Effect.

    3.7  Absence of Certain Changes.  Since December 31, 1996, there has been 
no material adverse change and no material adverse development in the 
business, properties, 

                                          7

<PAGE>

operations, financial condition, results of operations or prospects of the 
Company, except as disclosed in Schedule 3.7.

    3.8  Absence of Litigation.  Except as disclosed in Schedule 3.8, there 
is no action, suit, proceeding, inquiry or investigation before or by any 
court, public board, governmental agency or authority, or self-regulatory 
organization or body pending or, to the knowledge of the Company or any of 
its subsidiaries, threatened against or affecting the Company, any of its 
subsidiaries, or any of their respective directors or officers in their 
capacities as such, wherein an unfavorable decision, ruling or finding would 
have a Material Adverse Effect or would adversely affect the transactions 
contemplated by this Agreement or any of the documents contemplated hereby or 
which would adversely affect the validity or enforceability of, or the 
authority or ability of the Company to perform its obligations under, this 
Agreement or any of such other documents.  There are no facts which, if known 
by a potential claimant or governmental agency or authority, could give rise 
to a claim or proceeding which, if asserted or conducted with results 
unfavorable to the Company or any of its subsidiaries, could have a Material 
Adverse Effect.

    3.9  Disclosure.  No information relating to or concerning the Company 
set forth in this Agreement or provided to Purchaser in connection with the 
transactions contemplated hereby contains an untrue statement of a material 
fact or omits to state a material fact necessary in order to make the 
statements made herein or therein, in light of the circumstances under which 
they were made, not misleading.  Except for the execution and performance of 
this Agreement, no material fact (within the meaning of the federal 
securities laws of the United States) exists with respect to the Company or 
any of its subsidiaries which has not been publicly disclosed.

    3.10 Acknowledgment Regarding Purchaser's Purchase of the Securities.  
The Company acknowledges and agrees that Purchaser is not acting as a 
financial advisor or fiduciary of the Company (or in any similar capacity) 
with respect to this Agreement or the transactions contemplated hereby, that 
this Agreement and the transaction contemplated hereby, and the relationship 
between Purchaser and the Company, are "arms-length", and that any statement 
made by Purchaser, or any of its representatives or agents, in connection 
with the Agreement or the transactions contemplated hereby is not advice or a 
recommendation, is merely incidental to Purchaser's purchase of the 
Securities and has not been relied upon in any way by the Company, its 
officers, directors or other representatives.  The Company further represents 
to Purchaser that the Company's decision to enter into this Agreement and the 
transactions contemplated hereby has been based solely on an independent 
evaluation by the Company and its representatives.

    3.11 Current Public Information.  The Company currently meets the 
"Registrant eligibility requirements" set forth in the general instructions to 
Form S-3 under the Securities Act.

    3.12 No General Solicitation.  Neither the Company nor any person acting 
on behalf of the Company has conducted any "general solicitation," as 
described in Rule 502(c) under Regulation D, with respect to any of the 
Securities being offered hereby.

    3.13 No Integrated Offering.  Neither the Company, nor any if its 
affiliates, nor any person acting on its or their behalf, has directly or 
indirectly made any offers or sales of any security or solicited any offers 
to buy any security under circumstances that would prevent the parties hereto 
from consummating the transactions contemplated hereby pursuant to an 

                                          8

<PAGE>

exemption from registration under the Securities Act pursuant to the 
provisions of Regulation D.  The transactions contemplated hereby are exempt 
from the registration requirements of the Securities Act, assuming the 
accuracy of the representations and warranties herein contained of Purchaser 
to the extend relevant for such determination.  The issuance of the 
Securities to the Purchaser will not be integrated with any other issuance of 
the Company's Securities (past, present, or future) which requires 
stockholder approval under the rules of the NASDAQ stock market.

    3.14 No Brokers.  The Company has taken no action which would give rise 
to any claim by any person for brokerage commissions, finder's fees or 
similar payments to Purchaser relating to this Agreement or the transactions 
contemplated hereby, except for dealings with Wharton Capital and Coppers & 
Lybrand Securities LLP (the fees of which shall be paid in full by the 
Company). The Company will indemnify Purchaser from and against any fees and 
expenses sought or other claims made by Wharton Capital and Coppers & Lybrand 
Securities LLP.

    3.15 Acknowledgment of Terms and Nature of Securities.  The Company's 
executive officers and directors have studied and fully understand the terms 
and nature of the securities being sold hereunder.  The board of directors of 
the Company has concluded in its good faith business judgment that such 
issuance is in the best interests of the Company.

    3.16 Intellectual Property.  Each of the Company and its subsidiaries 
owns or possesses adequate and enforceable rights to use all patents, patent 
applications, trademarks, trademark applications, trade names, service marks, 
copyrights, copyright applications, licenses, know-how (including trade 
secrets and other unpatented and/or unpatentable proprietary or confidential 
information, systems or procedures) and other similar rights and proprietary 
knowledge (collectively, "Intangibles") used or necessary for the conduct of 
its business as now being conducted and as previously described in the 
Company's Annual Report on Form 10-KSB for its most recently ended fiscal 
year.  Neither the Company nor any subsidiary of the Company infringes on or 
is in conflict with any right or any other person with respect to any 
Intangibles nor is there any claim or infringement made by a third party 
against or involving the Company or any of its subsidiaries, which 
infringement, conflict or claim, individually or in the aggregate, if the 
subject of an unfavorable decision, ruling or finding, would have a Material 
Adverse Effect.

    3.17 Foreign Corrupt Practices.  Neither the Company, nor any of its 
subsidiaries, nor any director, officer, agent, employee or other person 
acting on behalf of the Company or any subsidiary has, in the course of his 
actions for, or on behalf of, the Company, used any corporate funds for any 
unlawful contribution, gift, entertainment or other unlawful expenses 
relating to political activity; made any direct or indirect unlawful payment 
to any foreign or domestic government official or employee from corporate 
funds; violated or is in violation of any provision of the U.S. Foreign 
Corrupt Practices Act of 1977, as amended; or made any bribe, rebate, payoff, 
influence payment, kickback or other unlawful payment to any foreign or 
domestic government official or employee.  Without limiting the generality of 
the foregoing, the Company and its subsidiaries have not directly or 
indirectly made or agreed to make (whether or not said payment is lawful) any 
payment to obtain, or with respect to, sales other than usual and regular 
compensation to its or their employees and sales representatives with respect 
to such sales.

                                          9

<PAGE>

    3.18 Key Employees.  Each Key Employee (as defined below) is currently 
serving the Company in the capacity disclosed in Schedule 3.18.  No Key 
Employee, to the best of the knowledge of the Company and its subsidiaries, 
is, or is now expected to be, in violation of any material term of any 
employment contract, confidentiality, disclosure or proprietary information 
agreement, non-competition agreement, or any other contract or agreement or 
any restrictive covenant, and the continued employment of each Key Employee 
does not subject the Company or any of its subsidiaries to any liability with 
respect to any of the foregoing matters.  No Key Employee has, to the best of 
the knowledge of the Company and its subsidiaries, any intention to terminate 
or limit his employment with, or services to, the Company or any of its 
subsidiaries, nor is any such Key Employee subject to any constraints (e.g., 
limitation) which would cause such employee to be unable to devote his full 
time and attention to such employment or services.  "Key Employee" means each 
of individuals listed on Schedule 3.18.

    3.19 Certain Transactions.  Except as set forth on Schedule 3.19 and 
except for arm's length transactions pursuant to which the Company or any of 
its Subsidiaries makes payments in the ordinary course of business upon terms 
no less favorable than the Company or any of its Subsidiaries could obtain 
from third parties and other than the grant of stock options disclosed on 
Schedule 3.3, none of the officers, directors, or employees of the Company is 
presently a party to any transaction with the Company or any of its 
Subsidiaries (other than for services as employees, officers and directors), 
including any contract, agreement or other arrangement providing for the 
furnishing of services to or by, providing for rental of real or personal 
property to or from, or otherwise requiring payments to or from any officer, 
director or such employee or, to the knowledge of the Company, any 
corporation, partnership, trust or other entity in which any officer, 
director, or any such employee has a substantial interest or is an officer, 
director, trustee or partner.

    3.20 Internal Accounting Controls.  The Company and each of its 
Subsidiaries maintain a system of internal accounting controls sufficient, in 
the judgment of the Company's board of directors, to provide reasonable 
assurance that (i) transactions are executed in accordance with management's 
general or specific authorizations, (ii) transactions are recorded as 
necessary to permit preparation of financial statements in conformity with 
generally accepted accounting principles and to maintain asset 
accountability, (iii) access to assets is permitted only in accordance with 
management's general or specific authorization and (iv) the recorded 
accountability for assets is compared with the existing assets at reasonable 
intervals and appropriate action is taken with respect to any differences.

                                      ARTICLE IV
                                      COVENANTS
                                           
    4.1  Best Efforts.  The Company shall use its best efforts timely to 
satisfy each of the conditions described in Articles VI and VII of this 
Agreement.

    4.2  Securities Laws.  The Company agrees to file a Form D with respect 
to the Securities with the SEC as required under Regulation D and to provide 
a copy thereof to Purchaser within five (5) business days following the Date 
of Closing.  The Company agrees to file a Form 8-K disclosing this Agreement 
and the transactions contemplated hereby with the SEC within five business 
(5) days following the date of Closing.  Such Form 8-K shall include 

                                          10

<PAGE>

this Agreement and the related transaction documents as exhibits thereto.  
The Company shall, on or prior to the date of Closing, take such action as is 
necessary to sell the Securities to Purchaser in accordance with applicable 
securities laws of states of the United States, and shall provide evidence of 
any such action so taken to Purchaser on or prior to the date of Closing. 
Without limiting any of the Company's obligations under this Agreement, the 
Registration Rights Agreement or the Warrants, from and after the date of 
Closing, neither the Company nor any person acting on its behalf shall take 
any action which would adversely affect any exemptions from registration 
under the Securities Act with respect to the transactions contemplated hereby.

    4.3  Reporting Status.  For so long as the Purchaser owns any of the 
Securities or three (3) years from the Closing Date, whichever is sooner, the 
Company shall timely file all reports required to be filed with the SEC 
pursuant to the Exchange Act, and the Company shall not terminate its status 
as an issuer required to file reports under the Exchange Act even if the 
Exchange Act or the rules and regulations thereunder would permit such 
termination.  The Company will take all action necessary to continue to meet 
the registrant eligibility requirements set forth in the general instruction 
to Form S-3.

    4.4  Use of Proceeds.  The Company shall use the proceeds from the sale 
of the Common Shares and Warrants for general working capital needs, capital 
expenditures including software development for future contracts and expenses 
associated with new health care call center ventures.

    4.5  Restriction on Below Market Issuance of Securities.  (a) For a 
period of one hundred and eighty (180) days following the date of Closing 
(the "Restricted Period"), the Company shall not issue or agree to issue 
(except (i) to Purchaser pursuant to this Agreement, (ii) pursuant to any 
employee stock option, stock purchase or restricted stock plan of the Company 
in effect on the date hereof up to the aggregate amounts set forth on 
Schedule 4.5 hereto, (iii) pursuant to any existing security, option, 
warrant, scrip, call or commitment or right in each case or disclosed on 
Schedule 3.3 hereof or (iv) pursuant to a strategic joint venture or 
partnership entered into by the Company, undertaken at the reasonable 
discretion of the Board of Directors of the Company, the primary purpose of 
which is not to raise equity capital) any equity securities (including debt 
securities with an equity component) of the Company (or any security 
convertible into or exercisable or exchangeable, directly or indirectly, or 
equity securities of the Company) if such securities are issued at a price 
(or in the case of securities convertible into or exercisable or 
exchangeable, directly or indirectly, for Common Stock such securities 
provide for a conversion, exercise or exchange price) which may be less than 
the then current market price for Common Stock on the date of issuance (in 
the case of Common Stock) or the date of conversion, exercise or exchange (in 
the case of securities convertible into or exercisable or exchangeable, 
directly or indirectly, for Common Stock).

    4.6  Right of First Offer.  For a period of one year after the expiration 
of the Restricted Period, the Company shall not issue or sell, or agree to 
issue or sell any equity or debt securities of the Company (or any security 
convertible into or exercisable or exchangeable, directly or indirectly, for 
equity or debt securities of the Company) ("Future Offerings") unless the 
Company shall have first delivered to Purchaser at least fifteen (15) 
business days prior to the closing of such Future Offering, written notice 
describing the proposed Future Offering, 

                                          11

<PAGE>

including the terms and conditions thereof, and providing Purchaser and its 
affiliates an option during the ten (10) business days period following 
delivery of such notice to purchase up to the full amount of the securities 
being offered in the Future Offering on the same terms as contemplated by 
such Future Offering (the limitations referred to in this sentence are 
collectively referred to as the "Capital Raising Limitations").  The Capital 
Raising Limitations shall not apply to any transaction involving issuances of 
securities in connection with a bona fide merger or consolidation or exercise 
of options of employees, consultants or directors.  In addition, the Capital 
Raising Limitations also shall not apply to (a) the issuance of securities 
upon exercise of conversion of the Company's options, warrants or other 
convertible securities outstanding as of the date hereof or (b) the grant of 
additional options or warrants, or the issuance of additional securities, 
under any employee stock option, stock purchase or restricted stock plan of 
the Company up to the aggregate amounts set forth on Schedule 4.5 hereto.  
This Section 4.6 shall not limit the Company's obligations under Section 4.5 
above.  The Company shall prohibit any Common Stock or other security issued 
subject to the Capital Raising Limitations but not purchased by Purchaser 
from being converted, exercised or resold until the day following the first 
anniversary of the date of the Closing and shall take all actions necessary 
(including, without limitation, the issuance of a stop transfer order) to 
effect such prohibition.  Notwithstanding anything to the contrary contained 
herein, and without limiting any of the Company's other obligations in this 
Agreement, the Registration Rights Agreement or the Warrants, any securities 
issued in a Future Offering (whether or not to Purchaser) (and any security 
issued upon conversion, exercise or exchange of any of such security) shall 
be ineligible for conversion, exercise, exchange, resale and/or registration 
under Federal or state securities laws for a period of six (6) months 
following the closing of such Future Offering.

    4.7  Expenses.  The Company shall pay to Purchaser, or at its direction, 
at the Closing reimbursement for the expenses reasonably incurred by it and 
its affiliates and advisors in connection with the negotiation, preparation, 
execution, and delivery of this Agreement and the other agreements to be 
executed in connection herewith, including, without limitation, Purchaser's 
and its affiliates' and advisors' due diligence and attorneys' fees and 
expenses (the "Expenses"); provided, however, that the Company shall not be 
obliged under this Section 4.7 to reimburse more than an aggregate of 
$10,000.00 of such attorneys' fees and expenses.  From time to time 
thereafter, upon Purchaser's written request, the Company shall pay to 
Purchaser such Expenses, if any, not so paid at Closing and/or covered by 
such payment, in each case to the extent reasonably incurred by Purchaser up 
to the $10,000.00 maximum amount.

    4.8  Information.  For so long as the Purchaser owns any of the 
Securities or three (3) years from the Closing Date, whichever is sooner, the 
Company agrees to send the following reports to Purchaser until Purchaser 
transfers, assigns or sells all of its Securities:  (a) within three (3) days 
after the filing with SEC, a copy of its Annual Report on Form 10-KSB, its 
Quarterly Reports on Form 10-QSB, any proxy statements and any Current 
Reports on Form 8-KSB; and (b) within one (1) day after release, copies of 
all press releases issued by the Company or any if its subsidiaries.  The 
Company further agrees to promptly provide to Purchaser or assignee thereof 
(a "Holder") any information with respect to the Company, its properties, or 
its business or Holder's investment as such Holder may reasonably request; 
provided, however, that the Company shall not be required to give any Holder 
any material nonpublic information.  If any information requested by a Holder 
from the Company contains material nonpublic information, the Company shall 
inform the Holder in writing that the information requested contains material 

                                          12

<PAGE>

nonpublic information and shall in no event provide such information to 
Holder without the express prior written consent of such Holder after being 
so informed.

    4.9  Reservation of Shares.  The Company shall at times have authorized 
and reserved for the purpose of issuance of a sufficient number of shares to 
provide for the full exercise of the outstanding Warrants and issuance of the 
Warrant Shares in connection therewith and as otherwise required by the 
Warrants.  The Company shall not reduce the number of shares reserved for 
issuance upon exercise of the Warrants without the consent of Purchaser 
holding a majority in interest of the Warrants then held by Purchaser (said 
majority in interest to be determined based on the number of Warrant Shares 
issuable upon exercise of said Warrants).

    4.10 Listing. The Company shall promptly secure and maintain listing and 
trading of the Common Shares and Warrant Shares on the NASDAQ and any other 
national securities exchange or quotation system on which the Common Stock is 
then listed and for so long as Purchaser owns any of the Securities or three 
(3) years from the Closing Date, whichever is sooner, and comply in all 
respects with the Company's reporting, filing and other obligations under the 
by-laws or rules of the NASDAQ and any other national securities exchange or 
quotation system on which the Common Stock is then listed.

    4.11 Prospectus Delivery Requirement.  Purchaser understands that the 
Securities Act may require delivery of a prospectus relating to the Common 
Stock in connection with any sale thereof pursuant to a registration 
statement under the Securities Act covering the resale by Purchaser of the 
Common Stock being sold, and Purchaser shall use its reasonable efforts to 
comply with the applicable prospectus delivery requirements of the Securities 
Act, if any, in connection with any such sale.

    4.12 Intentional Acts or Omissions.  The Company shall not intentionally 
perform any act which if performed, or intentionally omit to perform any act 
which, if omitted to be performed, would prevent or excuse the performance of 
this Agreement or any of the transactions contemplated hereby.

    4.13 Corporate Existence.  So long as Purchaser beneficially owns any 
Securities or for three (3) years from the Closing Date, whichever is sooner, 
the Company shall maintain its corporate existence and shall not sell all or 
substantially all of the Company's assets, except in the event of a merger or 
consolidation or sale of all or substantially all of the Company's assets, 
where the surviving or successor entity in such transaction (i) assumes the 
Company's obligations hereunder and under the agreements and instruments 
entered into in connection herewith and (ii) is a publicly traded corporation 
whose Common Stock is listed for trading on NASDAQ, NASDAQ SmallCap, NYSE, or 
AMEX.

    4.14 Hedging Transactions.  The Company hereby expressly agrees that 
Purchaser shall not in any way be prohibited or restricted from any purchases 
or sales of any securities or other instruments of, or related to, the 
Company or any of its securities, including, without limitation, puts, call, 
futures contracts, short sales and hedging and arbitrage transactions as long 
as Purchaser complies with applicable law.

                                          13

<PAGE>

                                      ARTICLE V
                     LEGEND REMOVAL, TRANSFER, AND CERTAIN SALES
                                           
    5.1  Removal of Legend.  The Legend shall be removed and the Company 
shall issue a certificate without any legend to the holder of any Security 
upon which such Legend is stamped, and a certificate for a security shall be 
originally issued without any legend, if, unless otherwise required by 
applicable state securities laws, (a) the sale of such Security is registered 
under the Securities Act, (b) such holder provides the Company with an 
opinion of counsel, in form, substance and scope customary for opinions of 
counsel in comparable transactions (the reasonable cost of which shall be 
borne by the Company), to the effect that a public sale or transfer of such 
Security may be made without registration under the Securities Act or (c) 
such Security can be sold pursuant to Rule 144.  Purchaser agrees to sell all 
Securities, including those represented by a certificate(s) from which the 
Legend has been removed, or which were originally issued without the Legend, 
pursuant to an effective registration statement and, if required, to deliver 
a prospectus in connection with such sale or in compliance with an exemption 
from the registration requirements of the Securities Act.  In the event the 
Legend is removed from any Security or any Security is issued without the 
Legend and thereafter the effectiveness of a registration statement covering 
the resale of such Security is suspended or the Company determines that a 
supplement or amendment thereto is required by applicable securities laws, 
then upon reasonable advance notice to Purchaser holding such Security, the 
Company may require that the Legend be placed on any such Security that 
cannot then be sold pursuant to an effective registration statement or Rule 
144 or with respect to which the opinion referred to in clause (b) next above 
has not been rendered, which Legend shall be removed when such Security may 
be sold pursuant to an effective registration statement or Rule 144 or such 
holder provides the opinion with respect thereto described in clause (b) next 
above.

    5.2  Transfer Agent Instructions.  The Company shall irrevocably instruct 
its transfer agent to issue certificates, registered in the name of Purchaser 
or its nominee, for the Common Shares and Warrant Shares in such amounts as 
specified from time to time by Purchaser to the Company.  Such certificates 
shall bear a legend only in the form of the Legend and only to the extend 
permitted by Section 5.1 above.  The Company warrants that no instruction 
other than such instructions referred to in this Article V, and no stop 
transfer instructions other than stop transfer instructions to give effect to 
Section 2.6 hereof in the case of the Common Shares and Warrant Shares prior 
to registration thereof under the Securities Act, will be given by the 
Company to its transfer agent and that the Securities shall otherwise be 
freely transferable on the books and records of the Company to the extent 
provided in this Agreement and the Registration Rights Agreement.  Nothing in 
this Section shall affect in any way Purchaser's obligations and agreement 
set forth in Section 5.1 hereof to resell the Securities pursuant to an 
effective registration statement and to deliver a prospectus in connection 
with such sale or in compliance with an exemption from the registration 
requirements of applicable securities laws. Without limiting the foregoing, 
if (a) Purchaser provides the Company with an opinion of counsel, which 
opinion of counsel shall be in form, substance and scope customary for 
opinions of counsel in comparable transactions (the reasonable cost of which 
shall be borne by the Company), to the effect that the Securities to be sold 
or transferred may be sold or transferred pursuant to an exemption from 
registration or (b) Purchaser transfers Securities to an affiliate or 
pursuant to Rule 144, the Company shall permit the transfer, and, in the case 
of the Common Shares and Warrant Shares, promptly instruct its transfer agent 
to issue one or more certificates in such name 

                                          14

<PAGE>

and in such denomination as specified by Purchaser in order to effect such a 
transfer or sale.  The Company acknowledges that a breach by it of its 
obligations hereunder will cause irreparable harm to Purchaser by vitiating 
the intent and purpose of the transaction contemplated hereby.  Accordingly, 
the Company acknowledges that the remedy at law for a breach of its 
obligations under this Article V will be inadequate and agrees, in the event 
of a breach of threatened breach by the Company of the provisions of this 
Article V, that Purchaser shall be entitled, in addition to all other 
available remedies, to an injunction restraining any breach and requiring 
immediate issuance and transfer, without the necessity of showing economic 
loss and without any bond or other security being required.

                                      ARTICLE VI
                    CONDITIONS TO THE COMPANY'S OBLIGATION TO SELL
                                           
    6.1  Conditions to the Company's Obligation to Sell.  The obligation of 
the Company hereunder to issue and sell the Common Shares and Warrants to 
Purchaser at the Closing is subject to the satisfaction, as of the date of 
the Closing and with respect to Purchaser, of each of the following 
conditions thereto, provided that these conditions are for the Company's sole 
benefit and may be waived by the Company at any time in its sole discretion:

    (a)  Purchaser shall have executed the signature page to this Agreement
         and the Registration Rights Agreement and delivered the same to the
         Company.
    (b)  Purchaser shall deliver the applicable Purchase Price for the Common
         Shares and Warrants purchased at the Closing.
    (c)  The representations and warranties of Purchaser shall be true and
         correct as of the date when made and as of the Closing as though made
         at the that time, and Purchaser shall have performed, satisfied and
         complied in all material respects with the covenants and agreements
         required by this Agreement to be performed or complied with by
         Purchaser at or prior to the Closing.
    (d)  No statute, rule, regulation, executive order, decree, ruling or
         injunction shall have been enacted, entered, promulgated, or endorsed
         by any court or governmental authority of competent jurisdiction or
         any self-regulatory organization having authority over the matters
         contemplated hereby which restricts or prohibits the consummation of
         any of the transactions contemplated by this Agreement.

                                     ARTICLE VII
                CONDITIONS TO EACH PURCHASER'S OBLIGATION TO PURCHASE
                                           
    The obligation of Purchaser hereunder to purchase the Common Shares and 
Warrants to be purchased by it on the date of the Closing is subject to the 
satisfaction of each of the following conditions, provided that these 
conditions are for Purchaser's sole benefit and may be waived by Purchaser 
(with respect to it) at any time in Purchaser's sole discretion:

    (a)  The Company shall have executed the signature page to this Agreement
         and the Registration Rights Agreement and delivered the same to
         Purchaser.
                                          15

<PAGE>

    (b)  The Company shall have delivered duly executed Warrants and
         certificates for the Common Shares (in each case in such denominations
         as Purchaser shall request) being so purchased by Purchaser at the
         Closing.

    (c)  The Common Stock shall be listed on the NASDAQ and trading in the
         Common Stock shall not have been suspended and no delisting or
         suspension shall be reasonably likely for the foreseeable future.
    (d)  The representations and warranties of the Company shall be true and
         correct as of the date when made and as of the Closing as though made
         at that time and the Company shall have performed, satisfied and
         complied with the covenants and agreements required by this Agreement
         to be performed or complied with by the Company at or prior to the
         Closing.  Purchaser shall have received a certificate, executed by the
         Chief Executive Officer of the Company, dated as of the Closing to the
         foregoing effect and as to such other matters as may be reasonably
         requested by Purchaser.

    (e)  No statute, rule, regulation, executive order, decree, ruling or
         injunction shall have been enacted, entered, promulgated or endorsed
         by any court or governmental authority of competent jurisdiction or
         any self-regulatory organization having authority over the matters
         contemplated hereby which prohibits the consummation of any of the
         transactions contemplated by this Agreement.

    (f)  Purchaser shall have received the officer's certificate described in
         Section 3.3 as of the Closing.

    (g)  Purchaser shall have received opinions of the Company's counsel, dated
         as of the Closing, in the form attached hereto as Exhibit C.

    (h)  The Company's transfer agent has agreed to act in accordance with
         irrevocable instructions in the form attached hereto as Exhibit D.

    (i)  The Company shall have entered into agreements with each of Gilbert V.
         Levin and M. Karen Levin restricting dispositions of Common Stock
         beneficially owned by such persons and in the form attached hereto as
         Exhibit E.

                                     ARTICLE VIII
                            GOVERNING LAW:  MISCELLANEOUS
                                           
    8.1  Governing Law:  Jurisdiction.  This Agreement shall be governed by 
and construed in accordance with the laws of the State of Delaware applicable 
to contracts made and to be performed in the State of Delaware.  The parties 
hereto irrevocably consent to the jurisdiction of the United States federal 
courts located in the State of Delaware and the state courts located in the 
County of New Castle in the State of Delaware in any suit or proceeding based 
on or arising under this Agreement or the transactions contemplated hereby 
and irrevocably agree that all claims in respect of such suit or proceeding 
may be determined in such courts.  The Company irrevocably waives the defense 
of an inconvenient forum to the maintenance of such suit or proceeding.  The 
Company further agrees that service of process upon the Company mailed by the 
first class mail shall be deemed in every respect effective service of 
process upon the Company in any suite or proceeding arising hereunder.  
Nothing 

                                          16

<PAGE>

herein shall affect Purchaser's right to serve process in any other manner 
permitted by law.  The parties hereto agree that a final non-appealable 
judgment in any such suit or proceeding shall be conclusive and may be 
enforced in other jurisdictions by suit on such judgment or in any other 
lawful manner.

    8.2  Counterparts.  This Agreement may be executed in two or more 
counterparts, including, without limitation, by facsimile transmission, all 
of which counterparts shall be considered one and the same agreement and 
shall become effective when counterparts have been signed by each party and 
delivered to the other party.  In the event any signature page is delivered 
by facsimile transmission, the party using such means of delivery shall cause 
additional original executed signature pages to be delivered to the other 
parties.

    8.3  Headings.  The headings of this Agreement are for convenience of 
reference and shall not form part of, or affect the interpretation of, this 
Agreement.

    8.4  Severability.  If any provision of this Agreement shall be invalid 
or unenforceable in any jurisdiction, such invalidity or unenforceability 
shall not affect the validity or enforceability of the remainder of this 
Agreement or the validity or enforceability of this Agreement in any other 
jurisdiction.

    8.5  Entire Agreement:  Amendments.  This Agreement and the instruments 
referenced herein contain the entire understanding of the parties with 
respect to the matters covered herein and therein and, except as specifically 
set forth herein or therein, neither the Company nor Purchaser makes any 
representation, warranty, covenant or undertaking with respect to such 
matters.  No provision of this Agreement may be waived other than by an 
instrument in writing signed by the party to be charged with enforcement and 
no provision of this Agreement may be amended other than by an instrument in 
writing signed by the Company and Purchaser.

    8.6  Notice.  Any notice herein required or permitted to be given shall 
be in writing and may be personally served or delivered by courier or by 
facsimile-machine confirmed telecopy, and shall be deemed delivered at the 
time and date of receipt (which shall include telephone line facsimile 
transmission). The addresses for such communications shall be:

              If to the Company:
              
              Biospherics Incorporated
              12051 Indian Creek Court
              Beltsville, MD  20705
              Telecopy:  301-210-4908/09
              Attention:  Dr. Gilbert V. Levin
              
                   with a copy to:
              
              Smith, Somerville & Case, L.L.C.
              Attorneys At Law
              100 Light Street
              Baltimore, MD  21202

                                          17

<PAGE>

              Telecopy:  410-385-8060
              Attention:  James Baker, Esq.
              
              If to RGC International Investors, LDC:
              
              c/o Rose Glen Capital Management, L.P.
              251 St. Asaphs Road
              Suite 200
              3 Bala Plaza East
              Bala Cynwyd, PA  19004
              Telecopy:  610-617-0570
              Attention:  Wayne D. Bloch
              
                   with a copy to:
              
              Ballard, Spahr, Andrews & Ingersoll
              1735 Market Street
              51st Floor
              Philadelphia, PA  19103
              Telecopy:  215-864-8999
              Attention:  Gerald J. Guarcini, Esq.

If to any other Purchaser, to such address set forth under Purchaser's name 
on the signature page hereto executed by Purchaser.  Each party shall provide 
notice to the other parties of any change in address.

    8.7  Successors and Assigns.  This Agreement shall be binding upon and 
inure to the benefit of the parties and their successors and assigns.  
Neither the Company nor Purchaser shall assign this Agreement or any rights 
or obligations hereunder without any prior written consent of the other. 
Notwithstanding the foregoing, Purchaser may assign its rights and 
obligations hereunder to any of its "affiliates," as that term is defined 
under the Exchange Act, without the consent of the Company so long as such 
affiliate is an accredited investor.  This provision shall not limit 
Purchaser's right to transfer the Securities pursuant to the terms of this 
Agreement or to assign Purchasers' rights hereunder to any such transferee 
(and all such rights may in fact be so assigned to any such transferee).  
Notwithstanding anything to the contrary contained in this Agreement, 
Purchaser may pledge the Securities in connection with a bona fide margin 
arrangement.

    8.8  Third Party Beneficiaries.  This Agreement is intended for the 
benefit of the parties hereto and their respective permitted successors and 
assigns and is not for the benefit of, nor may any provision hereof be 
enforced by, any other person.

    8.9  Survival.  The representations and warranties of the Company and the 
agreements and covenants set forth in Articles III, IV, V and VIII shall 
survive the closing hereunder notwithstanding any due diligence investigation 
conducted by or on behalf of Purchaser.  The Company agrees to indemnify and 
hold harmless Purchaser and each of Purchaser's officers, directors, 
employees, partners, agents and affiliates for loss or damage arising as a 
result of or 

                                          18

<PAGE>

related to any breach by the Company of any of its representations or 
covenants set forth herein, including advancement of expenses as they are 
incurred.

    8.10 Public Filings:  Publicity.  Immediately following execution on this 
Agreement, the Company shall issue a press release with respect to the 
transactions contemplated hereby.  The Company and Purchaser shall have the 
right to approve before issuance any press releases (including the foregoing 
press release), SEC or other filings, or any other public statements, with 
respect to the transactions contemplated hereby; provided, however, that the 
Company shall be entitled, without the prior approval of Purchaser, to make 
any press release or SEC, NASDAQ, NASD or exchange filings with respect to 
such transactions as is required by applicable law and regulations (although 
Purchaser shall (to the extent time permits) be consulted by the Company in 
connection with any such press release prior to its release and shall be 
provided with a copy thereof.

    8.11 Further Assurances.  Each party shall do and perform, or cause to be 
done and performed, all such further acts and things, and shall execute and 
deliver all such other agreements, certificates, instruments and documents, 
as the other party may reasonably request in order to carry out the intent 
and accomplish the purposes of this Agreement and the consummation of the 
transactions contemplated hereby.

    8.12 Remedies.  No provision of this Agreement providing for any remedy 
to Purchaser shall limit any remedy which would otherwise be available to 
Purchaser at law or in equity.  Nothing in this Agreement shall limit any 
rights Purchaser may have with any applicable federal or state securities 
laws with respect to the investment contemplated hereby.

    8.13 Termination.  In the event that the Closing shall not have occurred 
on or before December 12, 1997, unless the parties agree otherwise, this 
Agreement shall terminate at the close of business on such date.

    8.14 No Strict Construction.  The language used in this Agreement will be 
deemed to be the language chosen by the parties to express their mutual 
intent, and no rules of strict construction will be applied against any party.

                                      * * * * *

                                      19
<PAGE>

    IN WITNESS WHEREOF, the undersigned Purchasers and the Company have 
caused this Agreement to be duly executed as of the date first above written.

PURCHASER:

RGC INTERNATIONAL INVESTORS, LDC

By: Rose Glen Capital Management, L.P.
    Investment Manager
    By: RGC General Partner Corp., as General Partner

By:  _____________________________

Its: _____________________________

RESIDENCE:  Cayman Islands

ADDRESS:

c/o Rose Glen Capital Management, L.P.
3 Bala Plaza East, Suite 200
251 St. Asaphs Road
Bala Cynwyd, PA  19004
Facsimile:   (610) 617-0570
Telephone:  (610) 617-5900

AGGREGATE NUMBER OF COMMON SHARES:  750,000

WARRANTS FOR AGGREGATE NUMBER OF WARRANT SHARES: 750,000


COMPANY:

BIOSPHERICS INCORPORATED

By:  _____________________________

Its: _____________________________

                                       20


<PAGE>


                                                                  Exhibit (10.1)

                                           
                                           
                                           
                               SCHEDULES TO SECURITIES
                                  PURCHASE AGREEMENT
                                           
                                           
                                           
                                           
                                           
                                           
                                           
                                           
                                           
                                           
                                           
    These Schedules are being provided in connection with the Securities
    Purchase Agreement dated as of December 12, 1997.  All undefined
    capitalized terms contained herein shall have the same meaning as set forth
    in the Securities Purchase Agreement.  It is understood and agreed that
    disclosure of any item on any one of the following Schedules shall
    constitute appropriate disclosure on all appropriate Schedules.


                                          1
<PAGE>


                                     Schedule 3.2
                                           
                              Authorization, Enforcement
                                           

    There are no further consents or authorizations of the Company, its board
of directors, or its stockholders or any other person, body or agency required
with respect to any of the transactions contemplated by the Securities Purchase
Agreement.


                                          2
<PAGE>

                                     Schedule 3.3
                                           
                                    Capitalization
                                           

    This schedule includes the authorized capital stock, the number of shares
issued and outstanding, the number of shares reserved for issuance pursuant to
the Company's stock option plans, the number of shares reserved for issuance
pursuant to securities (other than the Warrants) exercisable for, or convertible
into or exchangeable for any shares of Common Stock and the number of shares to
be initially reserved for issuance upon exercise of the Warrants:

<TABLE>
<CAPTION>
                                              At September 30, 1997
                                            -------------------------
                                                       Shares
                                                     ----------
<S>                                                  <C>
Common Stock, $0.005 par value,
18,000,000 shares authorized   

Issued, non-redeemable                               6,518,837
Issued, redeemable                                   1,577,253
                                                     ---------
                                                     8,096,090

Treasury Stock, at cost                                (69,006)
                                                     --------- 

                                                     8,027,084
                                                     ---------
                                                     ---------

</TABLE>

Nonqualified Stock Option Plan

    Under the Company's Nonqualified Stock Option Plan dated May 15, 1997 
(the 1987 plan), options may be granted to officers and other key employees 
to purchase up to 4,400,000 shares of common stock in amounts determined by 
the Board of Directors at a price not less than 50% of the fair market value 
of the stock on the date the options are granted, and for a term not to 
exceed five years and one month from the date of grant.

    To date, all options granted, except for those part of an anti-hostile 
takeover plan explained below, have been at the then-publicly quoted price of 
the stock.  The 1987 plan expired on May 14, 1997.  On November 17, 1997, the 
Company's Board of Directors approved the 1997 Stock Option Plan subject to 
stockholders' approval.  The 1997 plan provides 400,000 options for granting 
to officers, directors, and other key employees and contains terms similar to 
the 1987 plan.

                                          3
<PAGE>



                                     Schedule 3.3
                                           
                              Capitalization (Continued)
                                           

Outstanding Options Granted Under the 1987 Nonqualified Stock Option Plan

    Options as of September 30, 1997                  2,731,250(1)

    Price Range of Options Outstanding:               $1.4375 to $7.25

    Options Exercisable as of September 30, 1997:     554,750

(1) See attached summary of outstanding stock options.


Stock Redemption Agreement

    The Company has agreements with two officers-stockholders who 
beneficially own 39.7% of the outstanding common stock.  Upon their deaths, 
the Company may be required to redeem from their estates, the number of 
shares of the Company's stock necessary to pay estate taxes and 
administrative expenses of the estate, if any, up to $5,000,000.  Shares 
would be redeemed at the then current market price.  The Company is the 
beneficiary to an insurance policy on the lives of the two 
officers-stockholders, which the Company maintains to provide benefits of 
$5,000,000 for this agreement.

                                          4
<PAGE>



                                     Schedule 3.5
                                           
                                     No Conflicts
                                           

                                         None.



                                          5
<PAGE>



                                     Schedule 3.6
                                           
                            Registration and SEC Documents
                                           

    Since January 1, 1995, the Company has timely filed all reports, 
schedules, forms, statements and other documents required to be filed by it 
with the SEC pursuant to the reporting requirements of the Exchange Act.

                                          6
<PAGE>


                                     Schedule 3.7
                                           
                              Absence of Certain Changes
                                           

    Since December 31, 1996, there has been no material adverse change and no 
material adverse development in the business, properties, operations, 
financial condition, results of operations or prospects of the Company.  The 
Company has filed its quarterly report on Form 10-QSB for the three-month and 
nine-month periods ended September 30, 1997 on November 13, 1997 with the 
Securities and Exchange Commission.  In such filing, the Company reclassified 
deferred revenue of $1,000,000, which represents a non-refundable advance 
against future royalties from the D-tagatose licensing agreement with MD 
Foods Ingredients amba of Denmark from current to non-current.  The advance 
will be recoverable at 50% of such annual royalties.  As commercialization of 
D-tagatose is not anticipated prior to the summer of 1999, the deferred 
revenue has accordingly been reclassified as non-current.

    The Company's government contracts typically have a term of three to five 
years.  Several contracts were rebid in 1997, which represented over 25% of 
consolidated revenues.  The Company was successful in securing new contracts 
for two of three contracts which were rebid.  Both of these contract awards 
are being protested by the unsuccessful bidder(s).  The Company is 
aggressively protesting the award of a contract that it had performed for the 
last two years and was unsuccessful in securing award during the rebid 
process.  The Company believes that it will continue to provide services 
under this contract through at least September 30, 1998, as the protest is 
being resolved.

                                          7
<PAGE>


                                     Schedule 3.8
                                           
                                      Litigation
                                           

    Summarized below is a listing of all actions, suits, proceedings, 
inquiries or investigations before or by any court, public board, 
governmental agency or authority, or self-regulatory organization or body 
pending or threatened against or affecting the Company, any of its 
subsidiaries, or any of their respective directors or officers in their 
capacities as such:

    In the fourth quarter of 1997, the Company collected the outstanding 
amount owed to it by Tetra Technologies, Inc. ($100,000) and the Pennsylvania 
Merchant Group.  See Note 7 to the Company's Annual Report on 10-KSB for 
further discussion on this Tetra matter.  The Company has filed a lawsuit 
against Forbes for an article printed about the Company.  There have been 
motions for dismissal of the suit and counter motions against dismissal; a 
decision is pending from the judge on these motions.

    The Company received a notice of potential liability from the U.S. EPA. 
See Note 7 of the Company's Annual Report on Form 10-KSB for background on 
this matter.  There has been no correspondence between the Company and EPA 
regarding this claim during 1997.

    The Company is awaiting a final determination by the Department of Labor 
on the wage rates paid to employees at the Company's Cumberland, Maryland 
facility. The Government Accounting Office must rule/decide if the wage rates 
are applicable to the Company.  A decision is still pending.  If there is an 
unfavorable ruling to the Company, the Company has recourse through an 
equitable adjustment claim under its contract with the GSA/Federal 
Information Center.

                                          8
<PAGE>


                                    Schedule 3.18
                                           
                                    Key Employees
                                           

    Summarized below is a listing of Key Employees of Biospherics 
Incorporated and the capacity in which they currently serve.

         Dr. Gilbert Levin        President & CEO; Chairman of the Board
         Karen Levin              VP, Communications & Corporate Secretary
         Jeffrey W. Church        Executive VP & Chief Financial Officer
         Richard Levin            VP, Planning
         Raul Vera                VP, Technology

                                          9
<PAGE>




                                    Schedule 3.19
                                           
                                 Certain Transactions
                                           

    Consulting Agreements:  Each of Gilbert V. Levin and M. Karen Levin have 
entered into Consulting Agreements with the Company pursuant to which such 
individuals will provide post-employment consulting services to the Company.

    Retirement Agreements:  Each of Gilbert V. Levin and M. Karen Levin have 
entered into Supplemental Executive Retirement Plan Agreements with the 
Company pursuant to which such individuals would be entitled to certain 
post-employment payments.

    Copies of the above described Agreements have been furnished to Purchaser.


                                          10
<PAGE>


                                     Schedule 4.5
                                           
                             Restriction on Below Market
                                Issuance of Securities
                                           

    The Company has an Employees' Nonqualified Stock Option Plan, whereby 
options are granted to officers and key employees.  See Schedule 3.3 
Capitalization for further details regarding this plan.

    The Company has an informal plan with its outside Board directors whereby 
options are granted on an annual basis.  Historically these grants have 
averaged 4,000 options per outside directors.  There are currently six (6) 
outside directors on Biospherics' Board of Directors.

                                          11


<PAGE>

                                                                Exhibit (10.2)

                                   EXHIBIT A-1
                         to Securities Purchase Agreement

                    VOID AFTER 5:00 P.M. BELTSVILLE, MARYLAND
                             TIME ON DECEMBER 12, 2000

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER 
THE SECURITIES ACT OF 1933, AS AMENDED, OR THE SECURITIES LAWS OF ANY STATE 
OF THE UNITED STATES.  THE SECURITIES REPRESENTED HEREBY MAY NOT BE OFFERED 
OR SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION 
STATEMENT FOR THE SECURITIES UNDER APPLICABLE SECURITIES LAWS OR UNLESS 
OFFERED, SOLD OR TRANSFERRED PURSUANT TO AN AVAILABLE EXEMPTION FROM THE 
REGISTRATION REQUIRMETNS OF THOSE LAWS.

                                           Right to Purchase 375,000 Shares of
                                       Common Stock, par value $.005 per share
Date:  December 12, 1997


                             BIOSPHERICS INCORPORATED
                              STOCK PURCHASE WARRANT

     THIS CERTIFIES THAT, for value received, RGC International Investors, 
LDC, or its registered assigns, is entitled to purchase from Biospherics 
Incorporated, a Delaware corporation (the "Company"), at any time or from 
time to time during the period specified in Section 2 hereof, 375,000 fully 
paid and nonassessable shares of the Company's common stock, par value $.005 
per share (the "Common Stock"), at an exercise price of $4.00 per share (the 
"Exercise Price").  This Warrant is being issued pursuant to that certain 
Securities Purchase Agreement dated December 12, 1997 between the Company and 
the signatories thereto (the "Securities Purchase Agreement").  The number of 
shares of Common Stock purchaseable hereunder (the "Warrant Shares") and the 
Exercise Price are subject to adjustment as provided in Section 4 hereof. The 
term "Warrants" means this Warrant and the other warrants of the Company 
issued pursuant to the terms of the Securities Purchase Agreement.

     The term "Closing Price" means, for any security as of any date, the 
last reported sale price of such security on the principal securities 
exchange or trading market where such security is listed or traded as 
reported by Bloomberg Financial Markets or a comparable reporting service of 
national reputation selected by the Company and reasonably acceptable to the 
holder hereof (the "Holder") if Bloomberg Financial Markets is not then 
reporting sale prices of such security (collectively, "Bloomberg"), or if the 
foregoing does not apply, the last reported sale price of such security in 
the over-the-counter market on the electronic bulletin board of such security 
as reported by Bloomberg, or, if no sale price is reported for such security 
by Bloomberg, the average of the bid prices of any market makers for such 
security as reported in the "pink sheets" by the National Quotation Bureau, 
Inc.  If the Closing Price cannot be calculated for such 

                                       1
<PAGE>


security on such date on any of the foregoing bases, the Closing Price of 
such security on such date shall be the fair market value as reasonably 
determined by an investment bank firm selected by the Company and reasonably 
acceptable to the Holder with the costs of such appraisal to be borne by the 
Company.

     This Warrant is subject to the following terms, provisions, and 
conditions:

     1.   Mechanics of Exercise.  Subject to the provisions hereof, 
including, without limitation, the limitations contained in Section 7(f) 
hereof, this Warrant may be exercised as follows:

     (a)  Manner of Exercise.  This Warrant may be exercised by the Holder, 
in whole or in part, by the surrender of this Warrant (or evidence of loss, 
theft, destruction or mutilation thereof in accordance with Section 11(e) 
hereof), together with a completed exercise agreement in the Form of Exercise 
Agreement attached hereto as Exhibit 1 (the "Exercise Agreement"), to the 
Company at the Company's principal executive offices (or such other office or 
agency of the Company as it may designate by notice to the Holder), and upon 
(i) payment to the Company in cash, by certified or official bank check or by 
wire transfer for the account of the Company, of the Exercise Price for the 
Warrant Shares specified in the Exercise Agreement or (ii) if the resale of 
the Warrant Shares by the holder is not then registered pursuant to an 
effective registration statement under the Securities Act, delivery to the 
Company of a written notice of an election to effect a Cashless Exercise (as 
defined in Section 11(c) below) for the Warrant Shares specified in the 
Exercise Agreement.  The Warrant Shares so purchased shall be deemed to be 
issued to the Holder or Holder's designees, as the record owner of such 
shares, as of the date on which this Warrant shall have been surrendered, the 
contemplated Exercise Agreement shall have been delivered, and payment (or 
notice of an election to effect a Cashless Exercise) shall have been made for 
such shares as set forth above.

     (b)  Issuance of Certificates.  Subject to Section 1(c), certificates 
for the Warrant Shares so purchased, representing the aggregate number of 
shares specified in the Exercise Agreement, shall be delivered to the Holder 
within a reasonable time, not exceeding three (3) business days, after this 
Warrant shall have been so exercised (the "Delivery Period").  The 
certificates so delivered shall be in such denominations as may be requested 
by the Holder and shall be registered in the name of Holder or such other 
name as shall be designated by such Holder.  If this Warrant shall have been 
exercised only in part, then, unless this Warrant has expired, the Company 
shall, at its expense, at the time of delivery of such certificates, deliver 
to the Holder a new Warrant representing the number of shares with respect to 
which this Warrant shall not then have been exercised.

     (c)  Exercise Disputes.  In the case of any dispute with respect to an 
exercise, the Company shall promptly issue such number of shares of Common 
Stock as are not disputed in accordance with this Section.  If such dispute 
involves the calculation of the Exercise Price, the Company shall submit the 
disputed calculations to a "Big Six" independent accounting firm (selected by 
the Company) via facsimile within three (3) business days of receipt of the 
Exercise Agreement.  The accounting firm shall review the calculations and 
notify the Company and the converting Holder of the results no later than two 
(2) business days from the date it receives the disputed calculations.  The 
accounting firm's calculation shall be deemed conclusive, absent              

                                       2 
<PAGE>

manifest error.  The Company shall then issue the appropriate number of 
shares of Common Stock in accordance with this Section.

     (d)  Fractional Shares.  No fractional shares of Common Stock are to be 
issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Exercise Price of a 
share of Common Stock (as determined for exercise of this Warrant into whole 
shares of Common Stock); provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be rounded up to the next whole number.

     (e)  Buy-In.  If (i) the Company fails for any reason to deliver during 
the Delivery Period shares of Common Stock to Holder upon an exercise of this 
Warrant and (ii) after the applicable Delivery Period with respect to such an 
exercise, Holder purchases (in an open market transaction or otherwise) 
shares of Common Stock to make delivery upon a sale by Holder of the shares 
of Common Stock (the "Sold Shares") which Holder was entitled to receive upon 
such exercise (a "Buy-in"), the Company shall pay Holder (in addition to any 
other remedies available to Holder) the amount by which (x) Holder's total 
purchase price (including brokerage commission, if any) for the shares of 
Common Stock so purchased exceeds (y) the lesser of (A) the Exercise Price or 
(B) the net proceeds received by Holder from the sale of the Sold Shares. 
Holder shall provide the Company written notification indicating any amounts 
payable to Holder pursuant to this subsection.

     2.   Period of Exercise.  This Warrant is exercisable at any time or 
from time to time on or after the date hereof and before 5:00 P.M., 
Beltsville, Maryland, time on the third (3rd) anniversary of the date hereof 
(the "Exercise Period").

     3.   Certain Agreements of the Company.  The Company hereby covenants 
and agrees as follows:

     (a)  Shares to be Fully Paid.  All Warrant Shares will, upon issuance in 
accordance with the terms of this Warrant, be validly issued, fully paid, and 
nonassessable and free from all taxes, liens, claims and encumbrances.

     (b)  Reservation of Shares.  During the Exercise Period, the Company 
shall at all times have authorized, and reserved for the purpose of issuance 
upon exercise of this Warrant, a sufficient number of shares of Common Stock 
to provide for the exercise of this Warrant.

     (c)  Listing.  The Company shall promptly secure the listing of the 
shares of Common Stock issuable upon exercise of this Warrant upon the NASDAQ 
National Market ("NASDAQ") as required by Section 4.9 of the Securities 
Purchase Agreement and upon each national securities exchange or automated 
quotation system, if any, upon which shares of Common Stock are then listed 
or become listed and shall maintain, so long as any other shares of Common 
Stock shall be so listed, such listing of all shares of Common Stock from 
time to time issuable upon the exercise of this Warrant; and the Company 
shall so list on each national securities exchange or automated quotation 
system, as the case may be, and shall maintain such listing of any other 
shares of capital stock of the Company issuable upon the exercise of this 
Warrant so long as any 

                                       3
<PAGE>

shares of the same class shall be listed on such national securities exchange 
or automated quotations system.

     (d)  Certain Actions Prohibited.  The Company will not, by amendment of 
its charter or through any reorganization, transfer of assets, consolidation, 
merger, dissolution, issue or sale of securities, or any other voluntary 
action, avoid or seek to avoid the observance or performance of any of the 
terms to be observed or performed by it hereunder, but will at all times in 
good faith assist in carrying out of all the provisions of this Warrant and 
in the taking of all such actions as may reasonably by requested by the 
Holder of this Warrant in order to protect the exercise privilege of the 
Holder of this Warrant, consistent with the tenor and purpose of this 
Warrant.  Without limiting the generality of the foregoing, the Company (i) 
will not increase the par value of any shares of Common Stock receivable upon 
the exercise of this Warrant above the Exercise Price then in effect, and 
(ii) will take all such actions as may be necessary or appropriate in order 
that the Company may validly and legally issue fully paid and nonassessable 
shares of Common Stock upon the exercise of this Warrant.

     (e)  Successors and Assigns.  This Warrant will be binding upon any 
entity succeeding to the Company by merger, consolidation, or acquisition of 
all or substantially all of the Company's assets.

     4.   Antidilution Provisions.  During the Exercise Period, the Exercise 
Price and the number of Warrant Shares shall be subject to adjustment from 
time to time as provided in this Section 4.  In the event that any adjustment 
of the Exercise Price as required herein results in a fraction of a cent, 
such Exercise Price shall be rounded up or down to the nearest cent.

     (a)  Adjustment of Exercise Price and Number of Shares upon Issuance of 
Common Stock.  Except as otherwise provided in Section 4(c) and 4(e) hereof, 
if and whenever after the initial issuance of this Warrant, the Company 
issues or sells, or in accordance with Section 4(b) hereof is deemed to have 
issued or sold, any shares of Common Stock for no consideration or for a 
consideration per share less than the Market Price (as herein defined) on the 
date of issuance (a "Dilutive Issuance"), then effective immediately upon the 
Dilutive Issuance, the Exercise Price will be adjusted in accordance with the 
following formula:

          E' = E x  O + P/M
                    -------
                    CSDO

          where

          E'   =    the adjusted Exercise Price;
          E    =    the then current Exercise Price;
          M    =    the then current Market Price;
          O    =    the number of shares of Common Stock outstanding immediately
                    prior to the Dilutive Issuance;
          P    =    the aggregate consideration, calculated as set forth in 
                    Section 4(b) hereof, received by the Company upon such 
                    Dilutive Issuance; and
          CSDO =    the total number of shares of Common Stock Deemed 
                    Outstanding (as herein defined) immediately after the 
                    Dilutive Issuance.

                                       4
<PAGE>

     (b)  Effect of Exercise Price of Certain Events. For purposes of 
determining the adjusted Exercise Price under Section 4(a) hereof, the following
will be applicable:

          (i)    Issuance of Rights or Options.  If the Company in any manner 
issues or grants any warrants, rights or options, whether or not immediately 
exercisable, to subscribe for or to purchase Common Stock or other securities 
exercisable, convertible into or exchangeable for Common Stock ("Convertible 
Securities"), but not to include the grant or exercise of any stock or 
options which may hereafter be granted or exercised under any employee or 
Director benefit plan of the Company now existing or to be implemented in the 
future, so long as the issuance of such stock or options is approved by 
majority of the non-employee members of the Board  of Directors of the 
Company or a majority of the members of a committee of non-employee directors 
established for such purpose (such warrants, rights and options to purchase 
Common Stock or Convertible Securities are hereinafter referred to as 
"Options"), and the price per share for which Common Stock is issuable upon 
the exercise of such Options is less than the Market Price on the date of 
issuance ("Below Market Options"),then the maximum total number of shares of 
Common Stock issuable upon the exercise of all such Below Market Options 
(assuming full exercise, conversion or exchange of Convertible Securities, if 
applicable) will, as of the date of the issuance or grant of such Below 
Market Options, be deemed to be outstanding and to have been issued and sold 
by the Company for such price per share.  For purposes of the preceding 
sentence, the price per share for which Common Stock is issuable upon the 
exercise of such Below Market Options is determined by dividing (i) the total 
amount, if any, received or receivable by the Company as consideration for 
the issuance or granting of such Below Market Options, plus the minimum 
aggregate amount of additional consideration, if any, payable to the Company 
upon the exercise of all such Below Market Options, plus, in the case of 
Convertible Securities issuable upon the exercise of such Below Market 
Options, the minimum aggregate amount of additional consideration payable 
upon the exercise, conversion or exchange thereof at the time such 
Convertible Securities first become exercisable, convertible or exchangeable, 
by (ii) the maximum total number of shares of Common Stock issuable upon the 
exercise of all such Below Market Options (assuming full conversion of 
Convertible Securities, if applicable). No further adjustment to the Exercise 
Price will be made upon the actual issuance of such Common Stock upon the 
exercise of such Below Market Options or upon the exercise, conversion or 
exchange of Convertible Securities issuable upon exercise of such Below 
Market Options.

          (ii)   Issuance of Convertible Securities.

                 (A)  If the Company in any manner issues or sells any 
Convertible Securities, whether or not immediately convertible (other than 
where the same are issuable upon the exercise of Options) and the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange (as determined pursuant to Section 4(b)(ii)(B) if applicable) is 
less than the Market Price on the date of issuance, then the maximum total 
number of shares of Common Stock issuable upon the exercise, conversion or 
exchange of all such Convertible Securities will, as of the date of issuance 
of such Convertible Securities, be deemed to be outstanding and to have been 
issued and sold by the Company for such price per share.  For the purposes of 
the preceding sentence, the price per share for which Common Stock is 
issuable upon such exercise, conversion or exchange is determined by dividing 
(i) the total amount, if any, received or receivable by the Company as 
consideration for the issuance or sale of all such Convertible Securities, 
plus the minimum aggregate amount of additional consideration, if any,

                                       5
<PAGE>

payable to the Company upon the exercise, conversion or exchange thereof at 
the time such Convertible Securities first become exercisable, onvertible or 
exchangeable, by (ii) the maximum total number of share of Common Stock 
issuable upon the exercise, conversion or exchange of all such Convertible 
Securities.  No further adjustment to the Exercise Price will be made upon 
the actual issuances of such Common Stock upon exercise, conversion or 
exchange of such Convertible Securities.

                 (B)  If the Company in any manner issues or sells any 
Convertible Securities with a fluctuating conversion or exercise price or 
exchange ratio (a "Variable Rate Convertible Security"), then the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange for purposes of the calculation contemplated by Section 4(b)(ii)(A) 
shall be deemed to be the lowest price per share which would be applicable 
assuming that (1) all holding period and other conditions to any discounts 
contained in such Convertible Security have been satisfied, and (2) the 
Market Price on the date of issuance of such Convertible Security was 80% of 
the Market Price on such date (the "Assumed Variable Market Price").

          (iii)  Change in Option Price or Conversion Rate.  Except for the 
grant or exercise of any stock or options which may hereafter be granted or 
exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose, if there is a change 
at any time in (i) the amount of additional consideration payable to the 
Company upon the exercise of any Options; (ii) the amount of additional 
consideration, if any, payable to the Company upon the exercise, conversion 
or exchange or any Convertible Securities; or (iii) the rate at which any 
Convertible Securities are convertible into or exchangeable for Common Stock 
(other than under or by reason of provisions designed to protect against 
dilution), the Exercise Price in effect at the time of such change will be 
readjusted to the Exercise Price which would have been in effect at such time 
had such Options or Convertible Securities still outstanding provided for 
such changed additional consideration or changed conversion rate, as the case 
may be, at the time initially granted, issued or sold.

          (iv)   Treatment of Expired Options and Unexercised Convertible 
Securities.  If, in any case, the total number of shares of Common Stock 
issuable upon exercise of any Options or upon exercise, conversion or 
exchange of any Convertible Securities is not, in fact, issued and the rights 
to exercise such option or to exercise, convert or exchange such Convertible 
Securities shall have expired or terminated, the Exercise Price then in 
effect will be readjusted to the Exercise Price which would have been in 
effect at the time of such expiration or termination had such Options or 
Convertible Securities, to the extent outstanding immediately prior to such 
expiration or termination (other than in respect of the actual number of 
shares of Common Stock issued upon exercise or conversion thereof), never 
been issued.

          (v)    Calculation of Consideration Received. If any Common Stock, 
Options or Convertible Securities are issued, granted or sold for cash, the 
consideration received therefor the purposes of this Warrant will be the 
amount received by the Company therefor, before deduction of reasonable 
commissions, underwriting discounts or allowances or other reasonable 
expenses paid or incurred by the Company in connection with such issuance, 
grant or sale.  In case any 

                                       6
<PAGE>

Common Stock, Options or Convertible Securities are issued or sold for a 
consideration part or all of which shall be other than cash, the amount of 
the consideration other than cash received by the Company will be the fair 
market value of such consideration except where such consideration consists 
of freely-tradeable securities, in which case the amount of consideration 
received by the Company will be the Market Price thereof as of the date of 
receipt.  In case any Common Stock, Options or Convertible Securities are 
issued in connection with any merger or consolidation in which the Company is 
the surviving corporation, the amount of consideration therefor will be 
deemed to be the fair market value of such portion of the net assets and 
business of the non-surviving corporation as is attributable to such Common 
Stock, Options or Convertible Securities, as the case may be.  The fair 
market value of any consideration other than cash or securities will be 
determined in the good faith reasonable business judgment of the Board of 
Directors.

          (vi)   Exceptions to Adjustment of Exercise Price.  No adjustment 
to the Exercise Price will be made (i) upon the exercise of any warrants, 
options or convertible securities issued and outstanding on the date hereof 
in accordance with the terms of such securities as of such date; (ii) upon 
the grant or exercise of any stock or options which may hereafter be granted 
or exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose; (iii) upon the 
issuance of the Common Shares (as defined in the Securities Purchase 
Agreement) or Warrants in accordance with terms of the Securities Purchase 
Agreement; or (iv) upon the exercise of the Warrants.

     (c)  Subdivision or Combination of Common Stock. If the Company, at any 
time after the initial issuance of this Warrant, subdivides (by any stock 
split, stock dividend, recapitalization, reorganization, reclassifications or 
otherwise) its shares of Common Stock into a greater number of shares, then, 
after the date of record for effecting such subdivision, the Exercise Price 
in effect immediately prior to such subdivision will be proportionately 
reduced.  If the Company, at any time after the initial issuance of this 
Warrant, combines (by reverse stock split, recapitalization, reorganization, 
reclassification or otherwise) its shares of Common Stock into a smaller 
number of shares, then, after the date of record for effecting such 
combination, the Exercise Price in effect immediately prior to such 
combination will be proportionately increased.

     (d)  Adjustment in Number of Shares.  Upon each adjustment of the 
Exercise Price pursuant to the provisions of this Section 4, the number of 
shares of Common Stock issuable upon exercise of this Warrant shall be 
adjusted by multiplying a number equal to the Exercise Price in effect 
immediately prior to such adjustment by the number of shares of Common Stock 
issuable upon exercise of this Warrant immediately prior to such adjustment 
and dividing the product so obtained by the adjusted Exercise Price.

     (e)  Major Transactions.  If the Company shall consolidate with or merge 
into any corporation or sell or convey all or substantially all of its assets 
or reclassify its outstanding shares of Common Stock (other than by way of 
subdivision, or in case of any sale or conveyance of all or substantially all 
of the assets of the Company other than in connection with a plan of complete 
liquidation of the Company, or reduction of such shares) (each a "Major 
Transaction"), 

                                       7
<PAGE>

then each holder of a Warrant shall thereafter be entitled to receive 
consideration, in exchange for such Warrant, equal to the greater of, as 
determined in the sole discretion of such older: (i) a warrant to purchase 
(at the same aggregate exercise price and on the same terms and conditions as 
the Warrant surrendered) the number of shares of stock or securities or 
property of the Company, or of the entity resulting from such consolidation 
or merge (the "Major Transaction Consideration"), to which a holder of the 
number of shares of Common Stock delivered upon exercise of such Warrant 
would have been entitled upon such Major Transaction had the holder of such 
Warrant exercised (without regard to any limitations on exercise herein 
contained) the Warrant on the trading date immediately preceding the public 
announcement of the transaction resulting in such Major Transaction and had 
such Common Stock been issued and outstanding and had such holder been the 
holder of record of such Common Stock at the time of such Major Transaction, 
and the Company shall make lawful provision therefor as part of such 
consolidation, merger, sale, conveyance or reclassification; and (ii) cash 
paid by the Company in immediately available funds, in an amount equal to the 
Black-Scholes Amount (as defined herein) times the number of shares of Common 
Stock for which this Warrant was exercisable (without regard to any 
limitations on exercise herein contained) on the date immediately preceding 
the date of such Major Transaction.  No sooner than ten (10) days nor later 
than five (5) days prior to the consummation of the Major Transaction, but 
not prior to the public announcement of such Major Transaction, the Company 
shall deliver written notice ("Notice of Major Transaction") to each holder 
of Warrants, which Notice of Major Transaction shall be deemed to have been 
delivered one (1) business day following the Company's sending such notice by 
telecopy (provided that the Company sends a confirming copy of such notice on 
the same day by overnight courier) of such Notice of Major Transaction. Such 
Notice of Major Transaction shall indicate the amount and type of the Major 
Transaction Consideration which such holder would receive under clause (i) of 
this paragraph (e).  If the Major Transaction Consideration does not consist 
entirely of United States currency, such holder may elect to receive United 
States currency in an amount equal to the value of the Major Transaction 
Consideration in lieu of the Major Transaction Consideration by delivering 
notice of such election to the Company within five (5) days of the holder's 
receipt of the Notice of Major Transaction.  The Company will not effect any 
Major Transaction unless prior to the consummation thereof, the successor 
corporation (if other than the Company) assumes by written instrument the 
obligations under this Section 4 and the obligations to deliver to the Holder 
of this Warrant such shares of stock, securities or assets as, in accordance 
with the foregoing provisions, the Holder may be entitled to acquire.

      The "Black-Scholes Amount" shall be an amount determined by calculating 
the "Black-Scholes" value of an option to purchase one share of Common Stock 
on the applicable page on the Bloomberg online page, using the following 
variable values:  (i) the current market price of the Common Stock equal to 
the closing trade price on the last trading day before the date of the Notice 
of the Major Transaction; (ii) volatility of the Common Stock equal to the 
volatility of the Common Stock during the 100 trading day period preceding 
the date of the Notice of the Major Transaction; (iii) a risk free rate equal 
to the interest rate on the United States treasury bill or treasury note with 
a maturity corresponding to the remaining term of this Warrant on the date of 
the Notice of the Major Transaction; and (iv) an exercise price equal to the 
Exercise Price on the date of the Notice of the Major Transaction.  In the 
event such calculation function is no longer available utilizing the 
Bloomberg online page, the Holder shall calculate such amount in its sole 
discretion using the closest available alternative mechanism and variable 
values to those available utilizing the Bloomberg online page for such 
calculation function.

                                       8
<PAGE>

     (f)  Distribution of Assets.  In case the Company shall declare or make 
any distribution of its assets (or rights to acquire its assets) to holders 
of Common Stock as a partial liquidating dividend, by way of return of 
capital or otherwise (including any dividend or distribution to the Company's 
shareholders of cash or shares (or rights to acquire shares) of capital stock 
of a subsidiary) (a "Distribution"), at any time after the initial issuance 
of this Warrant, then the Holder shall be entitled upon exercise of this 
Warrant for the purchase of any or all shares of Common Stock subject hereto, 
to receive the amount of such assets (or rights) which would have been 
payable to the Holder has such Holder been the holder of such shares of 
Common Stock on the record date for the determination of shareholders 
entitled to such Distribution.

     (g)  Notices of Adjustment.  Upon the occurrence of any event which 
requires any adjustment of the Exercise Price, then, and in each such case, 
the Company shall give notice thereof to the Holder, which notice shall state 
the Exercise Price resulting from such adjustment and the increase or 
decrease in the number of Warrant Shares purchaseable at such price upon 
exercise, setting forth in reasonable detail the method of calculation and 
the facts upon which such calculation is based.  Such calculation shall be 
certified by the chief financial officer of the Company.

     (h)  Minimum Adjustment of Exercise Price.  No adjustment of the 
Exercise Price shall be made in an amount of less than 1% of the Exercise 
Price in effect at the time such adjustment is otherwise required to be made, 
but any such lesser adjustment shall be carried forward and shall be made at 
the time and together with the next subsequent adjustment which, together 
with any adjustments so carried forward, shall amount to not less than 1% of 
such Exercise Price.

     (i)  No Fractional Shares.  No fractional shares of Common Stock are to 
be issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Market Price of a 
share of Common Stock; provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be founded up to the next whole number.

     (j)  Other Notices.  In case at any time: 

          (i)    the Company shall declare any dividend upon the Common Stock 
payable in shares of stock of any class or make any other distribution to the 
holders of the Common Stock;

          (ii)   the Company shall offer for subscription pro rata to the 
holders of the Common Stock any additional shares of stock of any class or 
other rights;

          (iii)  there shall be any capital reorganization of the Company, or 
reclassification of the Common Stock, or consolidation or merger of the 
Company with or into, or sale of all or substantially all of its assets to, 
another corporation or entity; or

                                       9
<PAGE>

          (iv)   there shall be a voluntary or involuntary dissolution, 
liquidation or winding-up of the Company;

then, in each such case, the Company shall give to the Holder (a) the notice 
of the date on which the books of the Company shall close or a record shall 
be taken for determining the holders of Common Stock entitled to receive any 
such dividend, distribution, or subscription rights or for determining the 
holders of Common Stock entitled to vote in respect of any such 
reorganization, reclassification, consolidation, merger, sale, dissolution, 
liquidation or winding-up and (b) in the case of any such reorganization, 
reclassification, consolidation, merger, sale, dissolution, liquidation or 
winding-up, notice of the date (or, if not then known, a reasonable 
approximation thereof by the Company) when the same shall take place.  Such 
notice shall also specify the date on which the holders of Common Stock shall 
be entitled to receive such dividend, distribution, or subscription rights or 
to exchange their Common Stock for stock or other securities or property 
deliverable upon such reorganization, reclassification, consolidation, 
merger, sale, dissolution, liquidation or winding-up, as the case may be.  
Such notice shall be given at least 30 days prior to the record date or the 
date on which the Company's books are closed in respect thereto, but in no 
event earlier than public announcement of such proposed transaction or event. 
Failure to give any such notice or any defect therein shall not affect the 
validity of the proceedings referred to in clauses (i), (ii), (iii), and (iv) 
above.

     (k)  Certain Events.  If any event occurs of the type contemplated by 
the adjustment provision of this Section 4 but not expressly provided for by 
such provisions, the Company will give notice of such event as provided in 
paragraph 4(g) hereof, and the Company's Board of Directors will make an 
appropriate adjustment in the Exercise Price and the number of shares of 
Common Stock acquirable upon exercise of this Warrant so that the rights of 
the Holder shall neither be enhanced or diminished by such event.

     (l)  Certain Definitions.

          (i)    "Common Stock Deemed Outstanding" shall mean the number of 
shares of Common Stock actually outstanding (not including shares of Common 
Stock held in the treasury of the Company), plus (x) in case of any 
adjustment required by Section 4(a) resulting from the issuance of any 
Options, the maximum total number of shares of Common Stock issuable upon the 
exercise of the Options for which the adjustment is required (including any 
Common Stock issuable upon the conversion of Convertible Securities issuable 
upon the exercise of such Options), and (y) in the case of any adjustment 
required by Section 4(a) resulting from the issuance of any Convertible 
Securities, the maximum total number of shares of Common Stock issuable upon 
the exercise, conversion or exchange of the Convertible Securities for which 
the adjustment is required, as of the date of issuance of such Convertible 
Securities, if any.

          (ii)   "Market Price," as of any date, (i) means the average of the 
Closing Prices for the shares of Common Stock as reported to NASDAQ for the 
five (5) trading days immediately preceding such date, or (ii) if the NASDAQ 
is not the principal trading market for the Common Stock, the average of the 
last reported sale prices on the principal trading market for the Common 
Stock during the same period, or (iii) if market value cannot be calculated 
as off such date on any of the foregoing bases, the Market Price shall be the 
average fair market value 

                                       10
<PAGE>

as reasonably determined by an investment banking firm selected by the 
Company and reasonable acceptable to the Holders of a majority in interest of 
the Warrants, with the costs of the appraisal to be borne by the Company.  
The manner of determining the Market Price of the Common Stock set forth in 
the foregoing definition shall apply with respect to any other security in 
respect of which a determination as to market value must be made hereunder.

          (iii)  "Common Stock," for purposes of this Section 4, includes the 
Common Stock and any additional class of stock of the Company having no 
preference as to dividends or distributions on liquidation, provided that the 
shares purchaseable pursuant to this Warrant shall include only Common Stock 
in respect of which this Warrant is exercisable, or shares resulting from any 
subdivision or combination of such Common Stock, or in the case of any 
reorganization, reclassification, consolidation, merger or sale of the 
character referred to in Section 4(d) hereof, the stock or other securities 
or property provided for in such Section.

     5.   Issue Tax.  The issuance of certificates for Warrant Shares upon 
the exercise of this Warrant shall be made without charge to the Holder or 
such shares for any issuance tax or other costs in respect thereof, provided 
that the Company shall not be required to pay any tax which may be payable in 
respect of any transfer involved in the issuance and delivery of any 
certificate in a name other than the Holder.

     6.   No Rights or Liabilities as a Shareholder.  This Warrant shall not 
entitle the Holder to any voting rights or other rights as a shareholder of 
the Company.  No provision of this Warrant, in the absence of affirmative 
action by the Holder to purchase Warrant Shares, and no mere enumeration 
herein of the rights or privileges of the Holder, shall give rise to any 
liability of the Holder for the Exercise Price or as a shareholder of the 
Company, whether such liability is asserted by the Company or by creditors of 
the Company.

     7.   Transfer, Exchange, Redemption and Replacement of Warrant.

     (a)  Restriction of Transfer.  This Warrant and the rights granted to 
the Holder are transferable, in whole or in part, upon surrender of this 
Warrant, together with a properly executed assignment in the Form of 
Assignment attached hereto as Exhibit 2, at the office or agency of the 
Company referred to in Section 7(e) below, provided, however, that any 
transfer or assignment shall be subject to the provisions of Section 5.1 and 
5.2 of the Securities Purchase Agreement.  Until due presentment for 
registration of transfer on the books of the Company, the Company may treat 
the registered holder hereof as the owner and holder hereof for all purposes, 
and the Company shall not be affected by any notice to the contrary. 
Notwithstanding anything to the contrary contained herein, the registration 
rights described in Section 8 hereof are assignable only in accordance with 
the provisions of that certain Registration Rights Agreement, dated as of 
December 12, 1997, by and among the Company and the other signatories thereto 
(the "Registration Rights Agreement").  Upon exercise of this Warrant, the 
Holder will make representations and warranties substantially equivalent to 
the representations and warranties concerning investment intent contained in 
Article II of the Securities Purchase Agreement; provided that any such 
representations and warranties will not cover any investment intent which may 
or may not exist with respect to the resale of the Common Stock upon a 
registration pursuant to the Registration Rights Agreement.  No transfer of 
this Warrant to any investor who

                                       11
<PAGE>

is not an accredited investor will be permitted and each Holder agrees that 
such Holder will remain an accredited investor.

     (b)  Warrant Exchangeable for Different Denominations.  This Warrant is 
exchangeable, upon the surrender hereof by the Holder at the office or agency 
of the Company referred to in Section 7(e) below, for new Warrants, in the 
form hereof, of different denominations representing in the aggregate the 
right to purchase the number of shares of Common Stock which may be purchased 
hereunder, each of such new Warrants to represent the right to purchase such 
number of shares as shall be designated by the Holder of at the time of such 
surrender.

     (c)  Replacement of Warrant.  Upon receipt of evidence reasonably 
satisfactory to the Company of the loss, theft, destruction, or mutilation of 
this Warrant or, in the case of any such loss, theft, or destruction, upon 
delivery, of an indemnity agreement reasonably satisfactory in form and 
amount to the Company, or, in the case of any such mutilation, upon surrender 
and cancellation of this Warrant, the Company, at its expense, will execute 
and deliver, in lieu thereof, a new Warrants, in the form hereof, in such 
determinations as Holder may request.

     (d)  Cancellation:  Payment of Expenses.  Upon the surrender of this 
Warrant in connection with any transfer, exchange, or replacement as provided 
in this Section 7, this Warrant shall be promptly canceled by the Company.  
The Company shall pay all issuance taxes (other than securities transfer 
taxes) and charges payable in connection with the preparation, execution, and 
delivery of Warrants pursuant to this Section 7.

     (e)  Warrant Register.  The Company shall maintain, at its principal 
executive offices (or such other office or agency of the Company as it may 
designate by notice to the Holder), a register for this Warrant, in which the 
Company shall record the name and address of the person in whose name this 
Warrant has been issued, as well as the name and address of each transferee 
and each prior owner of this Warrant.

     (f)  Additional Restriction on Exercise or Transfer.  Notwithstanding 
anything to the contrary contained herein, the Warrants shall not be 
exercisable by the Holder to the extent (but only to the extent) that, if 
exercisable by Holder, Holder would beneficially own in excess of 9.9% (the 
"Applicable Percentage") of the shares of Common Stock.  To the extent the 
above limitation applies, the determination of whether the Warrants shall be 
exercisable (vis-a-vis other securities owned by Holder) and of which 
Warrants shall be exercisable (as among Warrants) shall be in the sole 
discretion of the Holder and submission of the Warrants for exercise shall be 
deemed to be the Holder's determination of whether such Warrants are 
exercisable (vis-a-vis other securities owned by Holder) and of which 
warrants are exercisable (among Warrants), in each case subject to such 
aggregate percentage limitation.  No prior inability to exercise Warrants 
pursuant to this paragraph shall have any effect on the applicability of the 
provisions of this paragraph with respect to any subsequent determination of 
exercisability.  For the purposes of this paragraph, beneficial ownership and 
all determinations and calculations, including without limitation, with 
respect to calculations of percentage ownership, shall be determined in 
accordance with Section 13(d) of the Securities Exchange Act of 1934, as 
amended, and Regulation 13D and G thereunder.  The provisions of this 
paragraph may be waived and/or implemented in a manner otherwise than 
strictly in conformity with the foregoing provisions of

                                       12
<PAGE>

this paragraph (i) with the approval of the Board of Directors of the Company 
and the Holders:  (i) with respect to any matter to cure any ambiguity 
herein, to correct this paragraph (or any portion hereof) which may be 
defective or inconsistent with the intended Applicable Percentage beneficial 
ownership limitation herein contained or to make changes or supplements 
necessary or desirable to properly give effect to such Applicable Percentage 
limitation; and (ii) with respect to any other matter, with the further 
consent of the holders of a majority of the then outstanding shares of Common 
Stock.  In addition, the provisions of this paragraph (i) may be waived by 
Holder upon ninety (90) days prior written notice from Holder to the Company. 
The limitations contained in this paragraph shall apply to a successor holder 
of Warrants if, and to the extent, elected by such successor holder 
concurrently with its acquisition of such Warrants, such election to be 
promptly confirmed in writing to the Company (provided no transfer or series 
of transfer to a successor holder or holders shall be used by a Holder to 
evade the limitations contained in this paragraph).

     8.   Registration Rights.  The initial holder of this Warrant (and 
certain assignees thereof) is entitled to the benefit of such registration 
rights in respect of the Warrant Shares as are set forth in the Registration 
Rights Agreement.

     9.   Notices.  Any notice herein required or permitted to be given shall 
be in writing and may be personally served or delivered by courier (including 
a recognized overnight delivery service) or by confirmed telecopy, and shall 
be deemed delivered at the time and date of receipt (which shall include 
telephone line facsimile transmission).  The addresses for such 
communications shall be:

          If to the Company:
          
               Biospherics Incorporated
               12051 Indian Creek Court
               Beltsville, MD  20705
               Telecopy:  301-210-4908
               Attention:  Dr. Gilbert V. Levin
               
                      with a copy to:
               
               Smith, Somerville & Case, L.L.C.
               Attorneys At Law
               100 Light Street
               Baltimore, MD  21202
               Telecopy:  410-385-8060
               Attention:  James Baker, Esq.
               
and if to the Holder, at such address as Holder shall have provided in 
writing to the Company, or at such other address as each party furnishes by 
notice given in accordance with this Section 9.

     11.  Governing Law: Jurisdiction.  This Warrant shall be governed by and 
construed in accordance with the laws of the State of Delaware applicable to 
contracts made and to be performed in the State of Delaware.  The Company 
irrevocably consents to the jurisdiction of the 

                                       13
<PAGE>

United States federal courts located in the County of New Castle in the State 
of Delaware in any suit or proceeding based on or arising under this Warrant 
and irrevocably agrees that all claims in respect of such suit or proceeding 
may be determined in such courts.  The Company irrevocably waives the defense 
of an inconvenient forum to the maintenance of such suit or proceeding. The 
Company agrees that a final non-appealable judgment in any such suit or 
proceeding shall be conclusive and may be enforced in other jurisdictions by 
suit on such judgment or in any other lawful manner.

     12.  Miscellaneous.

     (a)  Amendments.  This Warrant and any provision hereof may only be 
amended by an instrument in writing signed by the Company and the Holder.

     (b)  Descriptive Headings.  The descriptive headings of the several 
Sections of this Warrant are inserted for purposes of reference only, and 
shall not affect the meaning or construction of any of the provisions hereof.

     (c)  Cashless Exercise.  Notwithstanding anything to the contrary 
contained in this Warrant, this Warrant may be exercised by presentation and 
surrender of this Warrant to the Company at its principal executive offices 
with a written notice of the Holder's intention to effect a cashless 
exercise, including a calculation of the number of shares of Common Stock to 
be issued upon such exercise in accordance with the terms hereof (a "Cashless 
Exercise").  In the event of a Cashless Exercise, in lieu of paying the 
Exercise Price in cash, the Holder shall surrender this Warrant for the 
number of shares of Common Stock determined by multiplying the number of 
Warrant Shares to which it would otherwise be entitled by a fraction, the 
numerator of which shall be the difference between the then current Market 
Price per share of the Common Stock and the Exercise Price, and the 
denominator of which shall be such then current Market Price per share of 
Common Stock.

     (d)  Assignability.  This Warrant shall be binding upon the Company and 
its successors and assigns and shall inure to the benefit of Holder and its 
successors and assigns.  The Holder shall notify the Company upon the 
assignment of this Warrant.

                                   * * * * *

     IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by 
its duly authorized officer.

                                       BIOSPHERICS INCORPORATED

                                   By:
                                      --------------------------------

                                   Name:
                                         -----------------------------

                                   Title:
                                         -----------------------------

                                       14
<PAGE>

                         FORM OF EXERCISE AGREEMENT

          (To be Executed by the Holder in order to Exercise the Warrant)

     The undersigned hereby irrevocably exercises the right to purchase 
____________ of the shares of common stock of Biospherics Incorporated, a 
Delaware corporation (the "Company"), evidenced by the attached Warrant, and 
herewith makes payment of the Exercise Price with respect to such shares in 
full or, if the resale of the Common Stock by the undersigned is not 
currently registered pursuant to an effective registration statement under 
the Securities Act of 1933, as amended, elects to effect a Cashless Exercise 
pursuant to the terms of the Warrant, all in accordance with the conditions 
and provisions of said Warrant.

     (i)  The undersigned agrees not to offer, sell, transfer or otherwise 
dispose of any Common Stock obtained on exercises of the Warrant, except 
under circumstances that will not result in a violation of the Securities Act 
of 1933, as amended, or any state securities laws.

     (ii) The undersigned requests that stock certificates for such shares be 
issued, and a Warrant representing any unexercised portion hereof be issued, 
pursuant to the Warrant in the name of the Holder (or such other person or 
persons indicated below) and delivered to the undersigned (or designee(s) at 
the address (or addresses) set forth below:

Date:
     ------------------------          ----------------------------------
                                       Signature of Holder


                                       ----------------------------------
                                       Name of Holder (Print)

                                       Address:

                                       ----------------------------------

                                       ----------------------------------

                                       15
<PAGE>


                               FORM OF ASSIGNMENT

     FOR VALUE RECEIVED, the undersigned hereby sells, assigns, and transfers 
all rights of the undersigned under the within Warrant, with respect to the 
number of shares of Common Stock covered thereby set forth herein below, to:

Name of Assignee                 Address                 No. of Shares
- ----------------                 -------                 -------------

, and hereby irrevocably constitutes and appoints _____________________________
as agent and attorney-in-fact to transfer said Warrant on the books of the
within-named corporation, with full power of substitution in the premises.

Date:
      ---------------------, -----------

In the presence of:

- ----------------------------------------

                                    Name:
                                         -------------------------------

                                    Signature:
                                              --------------------------

                                    Title of Signing Officer or Agent (if any):

                                    ------------------------------------

                                    Address:
                                            ----------------------------

                                    ------------------------------------

                                    Note: The above signature should
                                          correspond exactly with the name
                                          on the face of the within Warrant.

                                       16


<PAGE>

                                                                 Exhibit (10.3)

                                     EXHIBIT A-2
                           to Securities Purchase Agreement
                                           
                      VOID AFTER 5:00 P.M. BELTSVILLE, MARYLAND
                              TIME ON DECEMBER 12, 2000
                                           
THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER 
THE SECURITIES ACT OF 1933, AS AMENDED, OR THE SECURITIES LAWS OF ANY STATE 
OF THE UNITED STATES.  THE SECURITIES REPRESENTED HEREBY MAY NOT BE OFFERED 
OR SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION 
STATEMENT FOR THE SECURITIES UNDER APPLICABLE SECURITIES LAWS OR UNLESS 
OFFERED, SOLD OR TRANSFERRED PURSUANT TO AN AVAILABLE EXEMPTION FROM THE 
REGISTRATION REQUIRMETNS OF THOSE LAWS.

                                            Right to Purchase 375,000 Shares of
                                        Common Stock, par value $.005 per share
Date:  December 12, 1997


                               BIOSPHERICS INCORPORATED
                                STOCK PURCHASE WARRANT
                                           
    THIS CERTIFIES THAT, for value received, RGC International Investors, 
LDC, or its registered assigns, is entitled to purchase from Biospherics 
Incorporated, a Delaware corporation (the "Company"), at any time or from 
time to time during the period specified in Section 2 hereof, 375,000 fully 
paid and nonassessable shares of the Company's common stock, par value $.005 
per share (the "Common Stock"), at an exercise price of $4.50 per share (the 
"Exercise Price").  This Warrant is being issued pursuant to that certain 
Securities Purchase Agreement dated December 12, 1997 between the Company and 
the signatories thereto (the "Securities Purchase Agreement").  The number of 
shares of Common Stock purchaseable hereunder (the "Warrant Shares") and the 
Exercise Price are subject to adjustment as provided in Section 4 hereof.  
The term "Warrants" means this Warrant and the other warrants of the Company 
issued pursuant to the terms of the Securities Purchase Agreement.

    The term "Closing Price" means, for any security as of any date, the last 
reported sale price of such security on the principal securities exchange or 
trading market where such security is listed or traded as reported by 
Bloomberg Financial Markets or a comparable reporting service of national 
reputation selected by the Company and reasonably acceptable to the holder 
hereof (the "Holder") if Bloomberg Financial Markets is not then reporting 
sale prices of such security (collectively, "Bloomberg"), or if the foregoing 
does not apply, the last reported sale price of such security in the 
over-the-counter market on the electronic bulletin board of such security as 
reported by Bloomberg, or, if no sale price is reported for such security by 
Bloomberg, the average of the bid prices of any market makers for such 
security as reported in the "pink sheets" by the National Quotation Bureau, 
Inc.  If the Closing Price cannot be calculated for such 

                                       1

<PAGE>

security on such date on any of the foregoing bases, the Closing Price of 
such security on such date shall be the fair market value as reasonably 
determined by an investment bank firm selected by the Company and reasonably 
acceptable to the Holder with the costs of such appraisal to be borne by the 
Company.

    This Warrant is subject to the following terms, provisions, and 
conditions:

    1.   Mechanics of Exercise.  Subject to the provisions hereof, including, 
without limitation, the limitations contained in Section 7(f) hereof, this 
Warrant may be exercised as follows:

    (a)  Manner of Exercise.  This Warrant may be exercised by the Holder, in 
whole or in part, by the surrender of this Warrant (or evidence of loss, 
theft, destruction or mutilation thereof in accordance with Section 11(e) 
hereof), together with a completed exercise agreement in the Form of Exercise 
Agreement attached hereto as Exhibit 1 (the "Exercise Agreement"), to the 
Company at the Company's principal executive offices (or such other office or 
agency of the Company as it may designate by notice to the Holder), and upon 
(i) payment to the Company in cash, by certified or official bank check or by 
wire transfer for the account of the Company, of the Exercise Price for the 
Warrant Shares specified in the Exercise Agreement or (ii) if the resale of 
the Warrant Shares by the holder is not then registered pursuant to an 
effective registration statement under the Securities Act, delivery to the 
Company of a written notice of an election to effect a Cashless Exercise (as 
defined in Section 11(c) below) for the Warrant Shares specified in the 
Exercise Agreement.  The Warrant Shares so purchased shall be deemed to be 
issued to the Holder or Holder's designees, as the record owner of such 
shares, as of the date on which this Warrant shall have been surrendered, the 
contemplated Exercise Agreement shall have been delivered, and payment (or 
notice of an election to effect a Cashless Exercise) shall have been made for 
such shares as set forth above.

    (b)  Issuance of Certificates.  Subject to Section 1(c), certificates for 
the Warrant Shares so purchased, representing the aggregate number of shares 
specified in the Exercise Agreement, shall be delivered to the Holder within 
a reasonable time, not exceeding three (3) business days, after this Warrant 
shall have been so exercised (the "Delivery Period").  The certificates so 
delivered shall be in such denominations as may be requested by the Holder 
and shall be registered in the name of Holder or such other name as shall be 
designated by such Holder.  If this Warrant shall have been exercised only in 
part, then, unless this Warrant has expired, the Company shall, at its 
expense, at the time of delivery of such certificates, deliver to the Holder 
a new Warrant representing the number of shares with respect to which this 
Warrant shall not then have been exercised.

    (c)  Exercise Disputes.  In the case of any dispute with respect to an 
exercise, the Company shall promptly issue such number of shares of Common 
Stock as are not disputed in accordance with this Section.  If such dispute 
involves the calculation of the Exercise Price, the Company shall submit the 
disputed calculations to a "Big Six" independent accounting firm (selected by 
the Company) via facsimile within three (3) business days of receipt of the 
Exercise Agreement.  The accounting firm shall review the calculations and 
notify the Company and the converting Holder of the results no later than two 
(2) business days from the date it receives the disputed calculations.  The 
accounting firm's calculation shall be deemed conclusive, absent 

                                      2

<PAGE>

manifest error.  The Company shall then issue the appropriate number of 
shares of Common Stock in accordance with this Section.

    (d)  Fractional Shares.  No fractional shares of Common Stock are to be 
issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Exercise Price of a 
share of Common Stock (as determined for exercise of this Warrant into whole 
shares of Common Stock); provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be rounded up to the next whole number.

    (e)  Buy-In.  If (i) the Company fails for any reason to deliver during 
the Delivery Period shares of Common Stock to Holder upon an exercise of this 
Warrant and (ii) after the applicable Delivery Period with respect to such an 
exercise, Holder purchases (in an open market transaction or otherwise) 
shares of Common Stock to make delivery upon a sale by Holder of the shares 
of Common Stock (the "Sold Shares") which Holder was entitled to receive upon 
such exercise (a "Buy-in"), the Company shall pay Holder (in addition to any 
other remedies available to Holder) the amount by which (x) Holder's total 
purchase price (including brokerage commission, if any) for the shares of 
Common Stock so purchased exceeds (y) the lesser of (A) the Exercise Price or 
(B) the net proceeds received by Holder from the sale of the Sold Shares.  
Holder shall provide the Company written notification indicating any amounts 
payable to Holder pursuant to this subsection.

    2.   Period of Exercise.  This Warrant is exercisable at any time or from 
time to time on or after the date hereof and before 5:00 P.M., Beltsville, 
Maryland, time on the third (3rd) anniversary of the date hereof (the 
"Exercise Period").

    3.   Certain Agreements of the Company.  The Company hereby covenants and 
agrees as follows:

    (a)  Shares to be Fully Paid.  All Warrant Shares will, upon issuance in 
accordance with the terms of this Warrant, be validly issued, fully paid, and 
nonassessable and free from all taxes, liens, claims and encumbrances.

    (b)  Reservation of Shares.  During the Exercise Period, the Company 
shall at all times have authorized, and reserved for the purpose of issuance 
upon exercise of this Warrant, a sufficient number of shares of Common Stock 
to provide for the exercise of this Warrant.

    (c)  Listing.  The Company shall promptly secure the listing of the 
shares of Common Stock issuable upon exercise of this Warrant upon the NASDAQ 
National Market ("NASDAQ") as required by Section 4.9 of the Securities 
Purchase Agreement and upon each national securities exchange or automated 
quotation system, if any, upon which shares of Common Stock are then listed 
or become listed and shall maintain, so long as any other shares of Common 
Stock shall be so listed, such listing of all shares of Common Stock from 
time to time issuable upon the exercise of this Warrant; and the Company 
shall so list on each national securities exchange or automated quotation 
system, as the case may be, and shall maintain such listing of any other 
shares of capital stock of the Company issuable upon the exercise of this 
Warrant so long as any 

                                      3

<PAGE>

shares of the same class shall be listed on such national securities exchange 
or automated quotations system.

    (d)  Certain Actions Prohibited.  The Company will not, by amendment of 
its charter or through any reorganization, transfer of assets, consolidation, 
merger, dissolution, issue or sale of securities, or any other voluntary 
action, avoid or seek to avoid the observance or performance of any of the 
terms to be observed or performed by it hereunder, but will at all times in 
good faith assist in carrying out of all the provisions of this Warrant and 
in the taking of all such actions as may reasonably by requested by the 
Holder of this Warrant in order to protect the exercise privilege of the 
Holder of this Warrant, consistent with the tenor and purpose of this 
Warrant.  Without limiting the generality of the foregoing, the Company (i) 
will not increase the par value of any shares of Common Stock receivable upon 
the exercise of this Warrant above the Exercise Price then in effect, and 
(ii) will take all such actions as may be necessary or appropriate in order 
that the Company may validly and legally issue fully paid and nonassessable 
shares of Common Stock upon the exercise of this Warrant.

    (e)  Successors and Assigns.  This Warrant will be binding upon any 
entity succeeding to the Company by merger, consolidation, or acquisition of 
all or substantially all of the Company's assets.

    4.   Antidilution Provisions.  During the Exercise Period, the Exercise 
Price and the number of Warrant Shares shall be subject to adjustment from 
time to time as provided in this Section 4.  In the event that any adjustment 
of the Exercise Price as required herein results in a fraction of a cent, 
such Exercise Price shall be rounded up or down to the nearest cent.

    (a)  Adjustment of Exercise Price and Number of Shares upon Issuance of 
Common Stock.  Except as otherwise provided in Section 4(c) and 4(e) hereof, 
if and whenever after the initial issuance of this Warrant, the Company 
issues or sells, or in accordance with Section 4(b) hereof is deemed to have 
issued or sold, any shares of Common Stock for no consideration or for a 
consideration per share less than the Market Price (as herein defined) on the 
date of issuance (a "Dilutive Issuance"), then effective immediately upon the 
Dilutive Issuance, the Exercise Price will be adjusted in accordance with the 
following formula:

         E' = E x  O + P/M
                   -------
                    CSDO

         where

         E'   =    the adjusted Exercise Price;
         E    =    the then current Exercise Price;
         M    =    the then current Market Price;
         O    =    the number of shares of Common Stock outstanding immediately
                   prior to the Dilutive Issuance;
         P    =    the aggregate consideration, calculated as set forth in 
                   Section 4(b) hereof, received by the Company upon such 
                   Dilutive Issuance; and
         CSDO =    the total number of shares of Common Stock Deemed
                   Outstanding (as herein defined) immediately after the
                   Dilutive Issuance.

                                       4

<PAGE>

    (b)  Effect of Exercise Price of Certain Events.  For purposes of 
determining the adjusted Exercise Price under Section 4(a) hereof, the 
following will be applicable:

         (i)  Issuance of Rights or Options.  If the Company in any manner 
issues or grants any warrants, rights or options, whether or not immediately 
exercisable, to subscribe for or to purchase Common Stock or other securities 
exercisable, convertible into or exchangeable for Common Stock ("Convertible 
Securities"), but not to include the grant or exercise of any stock or 
options which may hereafter be granted or exercised under any employee or 
Director benefit plan of the Company now existing or to be implemented in the 
future, so long as the issuance of such stock or options is approved by 
majority of the non-employee members of the Board of Directors of the Company 
or a majority of the members of a committee of non-employee directors 
established for such purpose (such warrants, rights and options to purchase 
Common Stock or Convertible Securities are hereinafter referred to as 
"Options"), and the price per share for which Common Stock is issuable upon 
the exercise of such Options is less than the Market Price on the date of 
issuance ("Below Market Options"), then the maximum total number of shares of 
Common Stock issuable upon the exercise of all such Below Market Options 
(assuming full exercise, conversion or exchange of Convertible Securities, if 
applicable) will, as of the date of the issuance or grant of such Below 
Market Options, be deemed to be outstanding and to have been issued and sold 
by the Company for such price per share.  For purposes of the preceding 
sentence, the price per share for which Common Stock is issuable upon the 
exercise of such Below Market Options is determined by dividing (i) the total 
amount, if any, received or receivable by the Company as consideration for 
the issuance or granting of such Below Market Options, plus the minimum 
aggregate amount of additional consideration, if any, payable to the Company 
upon the exercise of all such Below Market Options, plus, in the case of 
Convertible Securities issuable upon the exercise of such Below Market 
Options, the minimum aggregate amount of additional consideration payable 
upon the exercise, conversion or exchange thereof at the time such 
Convertible Securities first become exercisable, convertible or exchangeable, 
by (ii) the maximum total number of shares of Common Stock issuable upon the 
exercise of all such Below Market Options (assuming full conversion of 
Convertible Securities, if applicable).  No further adjustment to the 
Exercise Price will be made upon the actual issuance of such Common Stock 
upon the exercise of such Below Market Options or upon the exercise, 
conversion or exchange of Convertible Securities issuable upon exercise of 
such Below Market Options.

         (ii) Issuance of Convertible Securities.

              (A)  If the Company in any manner issues or sells any 
Convertible Securities, whether or not immediately convertible (other than 
where the same are issuable upon the exercise of Options) and the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange (as determined pursuant to Section 4(b)(ii)(B) if applicable) is 
less than the Market Price on the date of issuance, then the maximum total 
number of shares of Common Stock issuable upon the exercise, conversion or 
exchange of all such Convertible Securities will, as of the date of issuance 
of such Convertible Securities, be deemed to be outstanding and to have been 
issued and sold by the Company for such price per share.  For the purposes of 
the preceding sentence, the price per share for which Common Stock is 
issuable upon such exercise, conversion or exchange is determined by dividing 
(i) the total amount, if any, received or receivable by the Company as 
consideration for the issuance or sale of all such Convertible Securities, 
plus the minimum aggregate amount of additional consideration, if any, 

                                      5

<PAGE>

payable to the Company upon the exercise, conversion or exchange thereof at 
the time such Convertible Securities first become exercisable, convertible or 
exchangeable, by (ii) the maximum total number of share of Common Stock 
issuable upon the exercise, conversion or exchange of all such Convertible 
Securities. No further adjustment to the Exercise Price will be made upon the 
actual issuances of such Common Stock upon exercise, conversion or exchange 
of such Convertible Securities.

              (B)  If the Company in any manner issues or sells any 
Convertible Securities with a fluctuating conversion or exercise price or 
exchange ratio (a "Variable Rate Convertible Security"), then the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange for purposes of the calculation contemplated by Section 4(b)(ii)(A) 
shall be deemed to be the lowest price per share which would be applicable 
assuming that (1) all holding period and other conditions to any discounts 
contained in such Convertible Security have been satisfied, and (2) the 
Market Price on the date of issuance of such Convertible Security was 80% of 
the Market Price on such date (the "Assumed Variable Market Price").

         (iii)     Change in Option Price or Conversion Rate.  Except for the 
grant or exercise of any stock or options which may hereafter be granted or 
exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose, if there is a change 
at any time in (i) the amount of additional consideration payable to the 
Company upon the exercise of any Options; (ii) the amount of additional 
consideration, if any, payable to the Company upon the exercise, conversion 
or exchange or any Convertible Securities; or (iii) the rate at which any 
Convertible Securities are convertible into or exchangeable for Common Stock 
(other than under or by reason of provisions designed to protect against 
dilution), the Exercise Price in effect at the time of such change will be 
readjusted to the Exercise Price which would have been in effect at such time 
had such Options or Convertible Securities still outstanding provided for 
such changed additional consideration or changed conversion rate, as the case 
may be, at the time initially granted, issued or sold.

         (iv) Treatment of Expired Options and Unexercised Convertible 
Securities.  If, in any case, the total number of shares of Common Stock 
issuable upon exercise of any Options or upon exercise, conversion or 
exchange of any Convertible Securities is not, in fact, issued and the rights 
to exercise such option or to exercise, convert or exchange such Convertible 
Securities shall have expired or terminated, the Exercise Price then in 
effect will be readjusted to the Exercise Price which would have been in 
effect at the time of such expiration or termination had such Options or 
Convertible Securities, to the extent outstanding immediately prior to such 
expiration or termination (other than in respect of the actual number of 
shares of Common Stock issued upon exercise or conversion thereof), never 
been issued.

         (v)  Calculation of Consideration Received.  If any Common Stock, 
Options or Convertible Securities are issued, granted or sold for cash, the 
consideration received therefor the purposes of this Warrant will be the 
amount received by the Company therefor, before deduction of reasonable 
commissions, underwriting discounts or allowances or other reasonable 
expenses paid or incurred by the Company in connection with such issuance, 
grant or sale.  In case any 

                                      6

<PAGE>

Common Stock, Options or Convertible Securities are issued or sold for a 
consideration part or all of which shall be other than cash, the amount of 
the consideration other than cash received by the Company will be the fair 
market value of such consideration except where such consideration consists 
of freely-tradeable securities, in which case the amount of consideration 
received by the Company will be the Market Price thereof as of the date of 
receipt.  In case any Common Stock, Options or Convertible Securities are 
issued in connection with any merger or consolidation in which the Company is 
the surviving corporation, the amount of consideration therefor will be 
deemed to be the fair market value of such portion of the net assets and 
business of the non-surviving corporation as is attributable to such Common 
Stock, Options or Convertible Securities, as the case may be.  The fair 
market value of any consideration other than cash or securities will be 
determined in the good faith reasonable business judgment of the Board of 
Directors.

         (vi) Exceptions to Adjustment of Exercise Price.  No adjustment to 
the Exercise Price will be made (i) upon the exercise of any warrants, 
options or convertible securities issued and outstanding on the date hereof 
in accordance with the terms of such securities as of such date; (ii) upon 
the grant or exercise of any stock or options which may hereafter be granted 
or exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose; (iii) upon the 
issuance of the Common Shares (as defined in the Securities Purchase 
Agreement) or Warrants in accordance with terms of the Securities Purchase 
Agreement; or (iv) upon the exercise of the Warrants.

    (c)  Subdivision or Combination of Common Stock.  If the Company, at any 
time after the initial issuance of this Warrant, subdivides (by any stock 
split, stock dividend, recapitalization, reorganization, reclassifications or 
otherwise) its shares of Common Stock into a greater number of shares, then, 
after the date of record for effecting such subdivision, the Exercise Price 
in effect immediately prior to such subdivision will be proportionately 
reduced. If the Company, at any time after the initial issuance of this 
Warrant, combines (by reverse stock split, recapitalization, reorganization, 
reclassification or otherwise) its shares of Common Stock into a smaller 
number of shares, then, after the date of record for effecting such 
combination, the Exercise Price in effect immediately prior to such 
combination will be proportionately increased.

    (d)  Adjustment in Number of Shares.  Upon each adjustment of the 
Exercise Price pursuant to the provisions of this Section 4, the number of 
shares of Common Stock issuable upon exercise of this Warrant shall be 
adjusted by multiplying a number equal to the Exercise Price in effect 
immediately prior to such adjustment by the number of shares of Common Stock 
issuable upon exercise of this Warrant immediately prior to such adjustment 
and dividing the product so obtained by the adjusted Exercise Price.

    (e)  Major Transactions.  If the Company shall consolidate with or merge 
into any corporation or sell or convey all or substantially all of its assets 
or reclassify its outstanding shares of Common Stock (other than by way of 
subdivision, or in case of any sale or conveyance of all or substantially all 
of the assets of the Company other than in connection with a plan of complete 
liquidation of the Company, or reduction of such shares) (each a "Major 
Transaction"), 

                                      7

<PAGE>

then each holder of a Warrant shall thereafter be entitled to receive 
consideration, in exchange for such Warrant, equal to the greater of, as 
determined in the sole discretion of such older:  (i) a warrant to purchase 
(at the same aggregate exercise price and on the same terms and conditions as 
the Warrant surrendered) the number of shares of stock or securities or 
property of the Company, or of the entity resulting from such consolidation 
or merge (the "Major Transaction Consideration"), to which a holder of the 
number of shares of Common Stock delivered upon exercise of such Warrant 
would have been entitled upon such Major Transaction had the holder of such 
Warrant exercised (without regard to any limitations on exercise herein 
contained) the Warrant on the trading date immediately preceding the public 
announcement of the transaction resulting in such Major Transaction and had 
such Common Stock been issued and outstanding and had such holder been the 
holder of record of such Common Stock at the time of such Major Transaction, 
and the Company shall make lawful provision therefor as part of such 
consolidation, merger, sale, conveyance or reclassification; and (ii) cash 
paid by the Company in immediately available funds, in an amount equal to the 
Black-Scholes Amount (as defined herein) times the number of shares of Common 
Stock for which this Warrant was exercisable (without regard to any 
limitations on exercise herein contained) on the date immediately preceding 
the date of such Major Transaction.  No sooner than ten (10) days nor later 
than five (5) days prior to the consummation of the Major Transaction, but 
not prior to the public announcement of such Major Transaction, the Company 
shall deliver written notice ("Notice of Major Transaction") to each holder 
of Warrants, which Notice of Major Transaction shall be deemed to have been 
delivered one (1) business day following the Company's sending such notice by 
telecopy (provided that the Company sends a confirming copy of such notice on 
the same day by overnight courier) of such Notice of Major Transaction.  Such 
Notice of Major Transaction shall indicate the amount and type of the Major 
Transaction Consideration which such holder would receive under clause (i) of 
this paragraph (e).  If the Major Transaction Consideration does not consist 
entirely of United States currency, such holder may elect to receive United 
States currency in an amount equal to the value of the Major Transaction 
Consideration in lieu of the Major Transaction Consideration by delivering 
notice of such election to the Company within five (5) days of the holder's 
receipt of the Notice of Major Transaction.  The Company will not effect any 
Major Transaction unless prior to the consummation thereof, the successor 
corporation (if other than the Company) assumes by written instrument the 
obligations under this Section 4 and the obligations to deliver to the Holder 
of this Warrant such shares of stock, securities or assets as, in accordance 
with the foregoing provisions, the Holder may be entitled to acquire.

    The "Black-Scholes Amount" shall be an amount determined by calculating 
the "Black-Scholes" value of an option to purchase one share of Common Stock 
on the applicable page on the Bloomberg online page, using the following 
variable values:  (i) the current market price of the Common Stock equal to 
the closing trade price on the last trading day before the date of the Notice 
of the Major Transaction; (ii) volatility of the Common Stock equal to the 
volatility of the Common Stock during the 100 trading day period preceding 
the date of the Notice of the Major Transaction; (iii) a risk free rate equal 
to the interest rate on the United States treasury bill or treasury note with 
a maturity corresponding to the remaining term of this Warrant on the date of 
the Notice of the Major Transaction; and (iv) an exercise price equal to the 
Exercise Price on the date of the Notice of the Major Transaction.  In the 
event such calculation function is no longer available utilizing the 
Bloomberg online page, the Holder shall calculate such amount in its sole 
discretion using the closest available alternative mechanism and variable 
values to those available utilizing the Bloomberg online page for such 
calculation function.

                                      8

<PAGE>

    (f)  Distribution of Assets.  In case the Company shall declare or make 
any distribution of its assets (or rights to acquire its assets) to holders 
of Common Stock as a partial liquidating dividend, by way of return of 
capital or otherwise (including any dividend or distribution to the Company's 
shareholders of cash or shares (or rights to acquire shares) of capital stock 
of a subsidiary) (a "Distribution"), at any time after the initial issuance 
of this Warrant, then the Holder shall be entitled upon exercise of this 
Warrant for the purchase of any or all shares of Common Stock subject hereto, 
to receive the amount of such assets (or rights) which would have been 
payable to the Holder has such Holder been the holder of such shares of 
Common Stock on the record date for the determination of shareholders 
entitled to such Distribution.

    (g)  Notices of Adjustment.  Upon the occurrence of any event which 
requires any adjustment of the Exercise Price, then, and in each such case, 
the Company shall give notice thereof to the Holder, which notice shall state 
the Exercise Price resulting from such adjustment and the increase or 
decrease in the number of Warrant Shares purchaseable at such price upon 
exercise, setting forth in reasonable detail the method of calculation and 
the facts upon which such calculation is based.  Such calculation shall be 
certified by the chief financial officer of the Company.

    (h)  Minimum Adjustment of Exercise Price.  No adjustment of the Exercise 
Price shall be made in an amount of less than 1% of the Exercise Price in 
effect at the time such adjustment is otherwise required to be made, but any 
such lesser adjustment shall be carried forward and shall be made at the time 
and together with the next subsequent adjustment which, together with any 
adjustments so carried forward, shall amount to not less than 1% of such 
Exercise Price.

    (i)  No Fractional Shares.  No fractional shares of Common Stock are to 
be issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Market Price of a 
share of Common Stock; provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be founded up to the next whole number.

    (j)  Other Notices.  In case at any time:

         (i)  the Company shall declare any dividend upon the Common Stock 
payable in shares of stock of any class or make any other distribution to the 
holders of the Common Stock;

         (ii) the Company shall offer for subscription pro rata to the 
holders of the Common Stock any additional shares of stock of any class or 
other rights;

         (iii)     there shall be any capital reorganization of the Company, 
or reclassification of the Common Stock, or consolidation or merger of the 
Company with or into, or sale of all or substantially all of its assets to, 
another corporation or entity; or

                                      9

<PAGE>

         (iv) there shall be a voluntary or involuntary dissolution, 
liquidation or winding-up of the Company;

then, in each such case, the Company shall give to the Holder (a) the notice 
of the date on which the books of the Company shall close or a record shall 
be taken for determining the holders of Common Stock entitled to receive any 
such dividend, distribution, or subscription rights or for determining the 
holders of Common Stock entitled to vote in respect of any such 
reorganization, reclassification, consolidation, merger, sale, dissolution, 
liquidation or winding-up and (b) in the case of any such reorganization, 
reclassification, consolidation, merger, sale, dissolution, liquidation or 
winding-up, notice of the date (or, if not then known, a reasonable 
approximation thereof by the Company) when the same shall take place.  Such 
notice shall also specify the date on which the holders of Common Stock shall 
be entitled to receive such dividend, distribution, or subscription rights or 
to exchange their Common Stock for stock or other securities or property 
deliverable upon such reorganization, reclassification, consolidation, 
merger, sale, dissolution, liquidation or winding-up, as the case may be.  
Such notice shall be given at least 30 days prior to the record date or the 
date on which the Company's books are closed in respect thereto, but in no 
event earlier than public announcement of such proposed transaction or event. 
 Failure to give any such notice or any defect therein shall not affect the 
validity of the proceedings referred to in clauses (i), (ii), (iii), and (iv) 
above.

    (k)  Certain Events.  If any event occurs of the type contemplated by the 
adjustment provision of this Section 4 but not expressly provided for by such 
provisions, the Company will give notice of such event as provided in 
paragraph 4(g) hereof, and the Company's Board of Directors will make an 
appropriate adjustment in the Exercise Price and the number of shares of 
Common Stock acquirable upon exercise of this Warrant so that the rights of 
the Holder shall neither be enhanced or diminished by such event.

    (l)  Certain Definitions.

         (i)  "Common Stock Deemed Outstanding" shall mean the number of 
shares of Common Stock actually outstanding (not including shares of Common 
Stock held in the treasury of the Company), plus (x) in case of any 
adjustment required by Section 4(a) resulting from the issuance of any 
Options, the maximum total number of shares of Common Stock issuable upon the 
exercise of the Options for which the adjustment is required (including any 
Common Stock issuable upon the conversion of Convertible Securities issuable 
upon the exercise of such Options), and (y) in the case of any adjustment 
required by Section 4(a) resulting from the issuance of any Convertible 
Securities, the maximum total number of shares of Common Stock issuable upon 
the exercise, conversion or exchange of the Convertible Securities for which 
the adjustment is required, as of the date of issuance of such Convertible 
Securities, if any.

         (ii) "Market Price," as of any date, (i) means the average of the 
Closing Prices for the shares of Common Stock as reported to NASDAQ for the 
five (5) trading days immediately preceding such date, or (ii) if the NASDAQ 
is not the principal trading market for the Common Stock, the average of the 
last reported sale prices on the principal trading market for the Common 
Stock during the same period, or (iii) if market value cannot be calculated 
as off such date on any of the foregoing bases, the Market Price shall be the 
average fair market value 

                                      10

<PAGE>

as reasonably determined by an investment banking firm selected by the 
Company and reasonable acceptable to the Holders of a majority in interest of 
the Warrants, with the costs of the appraisal to be borne by the Company.  
The manner of determining the Market Price of the Common Stock set forth in 
the foregoing definition shall apply with respect to any other security in 
respect of which a determination as to market value must be made hereunder.

         (iii)     "Common Stock," for purposes of this Section 4, includes 
the Common Stock and any additional class of stock of the Company having no 
preference as to dividends or distributions on liquidation, provided that the 
shares purchaseable pursuant to this Warrant shall include only Common Stock 
in respect of which this Warrant is exercisable, or shares resulting from any 
subdivision or combination of such Common Stock, or in the case of any 
reorganization, reclassification, consolidation, merger or sale of the 
character referred to in Section 4(d) hereof, the stock or other securities 
or property provided for in such Section.

    5.   Issue Tax.  The issuance of certificates for Warrant Shares upon the 
exercise of this Warrant shall be made without charge to the Holder or such 
shares for any issuance tax or other costs in respect thereof, provided that 
the Company shall not be required to pay any tax which may be payable in 
respect of any transfer involved in the issuance and delivery of any 
certificate in a name other than the Holder.

    6.   No Rights or Liabilities as a Shareholder.  This Warrant shall not 
entitle the Holder to any voting rights or other rights as a shareholder of 
the Company.  No provision of this Warrant, in the absence of affirmative 
action by the Holder to purchase Warrant Shares, and no mere enumeration 
herein of the rights or privileges of the Holder, shall give rise to any 
liability of the Holder for the Exercise Price or as a shareholder of the 
Company, whether such liability is asserted by the Company or by creditors of 
the Company.

    7.   Transfer, Exchange, Redemption and Replacement of Warrant.

    (a)  Restriction of Transfer.  This Warrant and the rights granted to the 
Holder are transferable, in whole or in part, upon surrender of this Warrant, 
together with a properly executed assignment in the Form of Assignment 
attached hereto as Exhibit 2, at the office or agency of the Company referred 
to in Section 7(e) below, provided, however, that any transfer or assignment 
shall be subject to the provisions of Section 5.1 and 5.2 of the Securities 
Purchase Agreement.  Until due presentment for registration of transfer on 
the books of the Company, the Company may treat the registered holder hereof 
as the owner and holder hereof for all purposes, and the Company shall not be 
affected by any notice to the contrary.  Notwithstanding anything to the 
contrary contained herein, the registration rights described in Section 8 
hereof are assignable only in accordance with the provisions of that certain 
Registration Rights Agreement, dated as of December 12, 1997, by and among 
the Company and the other signatories thereto (the "Registration Rights 
Agreement").  Upon exercise of this Warrant, the Holder will make 
representations and warranties substantially equivalent to the 
representations and warranties concerning investment intent contained in 
Article II of the Securities Purchase Agreement; provided that any such 
representations and warranties will not cover any investment intent which may 
or may not exist with respect to the resale of the Common Stock upon a 
registration pursuant to the Registration Rights Agreement.  No transfer of 
this Warrant to any investor who 

                                      11

<PAGE>

is not an accredited investor will be permitted and each Holder agrees that 
such Holder will remain an accredited investor.

    (b)  Warrant Exchangeable for Different Denominations.  This Warrant is 
exchangeable, upon the surrender hereof by the Holder at the office or agency 
of the Company referred to in Section 7(e) below, for new Warrants, in the 
form hereof, of different denominations representing in the aggregate the 
right to purchase the number of shares of Common Stock which may be purchased 
hereunder, each of such new Warrants to represent the right to purchase such 
number of shares as shall be designated by the Holder of at the time of such 
surrender.

    (c)  Replacement of Warrant.  Upon receipt of evidence reasonably 
satisfactory to the Company of the loss, theft, destruction, or mutilation of 
this Warrant or, in the case of any such loss, theft, or destruction, upon 
delivery, of an indemnity agreement reasonably satisfactory in form and 
amount to the Company, or, in the case of any such mutilation, upon surrender 
and cancellation of this Warrant, the Company, at its expense, will execute 
and deliver, in lieu thereof, a new Warrants, in the form hereof, in such 
determinations as Holder may request.

    (d)  Cancellation:  Payment of Expenses.  Upon the surrender of this 
Warrant in connection with any transfer, exchange, or replacement as provided 
in this Section 7, this Warrant shall be promptly canceled by the Company.  
The Company shall pay all issuance taxes (other than securities transfer 
taxes) and charges payable in connection with the preparation, execution, and 
delivery of Warrants pursuant to this Section 7.

    (e)  Warrant Register.  The Company shall maintain, at its principal 
executive offices (or such other office or agency of the Company as it may 
designate by notice to the Holder), a register for this Warrant, in which the 
Company shall record the name and address of the person in whose name this 
Warrant has been issued, as well as the name and address of each transferee 
and each prior owner of this Warrant.

    (f)  Additional Restriction on Exercise or Transfer.  Notwithstanding 
anything to the contrary contained herein, the Warrants shall not be 
exercisable by the Holder to the extent (but only to the extent) that, if 
exercisable by Holder, Holder would beneficially own in excess of 9.9% (the 
"Applicable Percentage") of the shares of Common Stock.  To the extent the 
above limitation applies, the determination of whether the Warrants shall be 
exercisable (vis-a-vis other securities owned by Holder) and of which 
Warrants shall be exercisable (as among Warrants) shall be in the sole 
discretion of the Holder and submission of the Warrants for exercise shall be 
deemed to be the Holder's determination of whether such Warrants are 
exercisable (vis-a-vis other securities owned by Holder) and of which 
warrants are exercisable (among Warrants), in each case subject to such 
aggregate percentage limitation.  No prior inability to exercise Warrants 
pursuant to this paragraph shall have any effect on the applicability of the 
provisions of this paragraph with respect to any subsequent determination of 
exercisability.  For the purposes of this paragraph, beneficial ownership and 
all determinations and calculations, including without limitation, with 
respect to calculations of percentage ownership, shall be determined in 
accordance with Section 13(d) of the Securities Exchange Act of 1934, as 
amended, and Regulation 13D and G thereunder.  The provisions of this 
paragraph may be waived and/or implemented in a manner otherwise than 
strictly in conformity with the foregoing provisions of 

                                      12

<PAGE>

this paragraph (i) with the approval of the Board of Directors of the Company 
and the Holders:  (i) with respect to any matter to cure any ambiguity 
herein, to correct this paragraph (or any portion hereof) which may be 
defective or inconsistent with the intended Applicable Percentage beneficial 
ownership limitation herein contained or to make changes or supplements 
necessary or desirable to properly give effect to such Applicable Percentage 
limitation; and (ii) with respect to any other matter, with the further 
consent of the holders of a majority of the then outstanding shares of Common 
Stock.  In addition, the provisions of this paragraph (i) may be waived by 
Holder upon ninety (90) days prior written notice from Holder to the Company. 
 The limitations contained in this paragraph shall apply to a successor 
holder of Warrants if, and to the extent, elected by such successor holder 
concurrently with its acquisition of such Warrants, such election to be 
promptly confirmed in writing to the Company (provided no transfer or series 
of transfer to a successor holder or holders shall be used by a Holder to 
evade the limitations contained in this paragraph).

    8.   Registration Rights.  The initial holder of this Warrant (and 
certain assignees thereof) is entitled to the benefit of such registration 
rights in respect of the Warrant Shares as are set forth in the Registration 
Rights Agreement.

    9.   Notices.  Any notice herein required or permitted to be given shall 
be in writing and may be personally served or delivered by courier (including 
a recognized overnight delivery service) or by confirmed telecopy, and shall 
be deemed delivered at the time and date of receipt (which shall include 
telephone line facsimile transmission).  The addresses for such 
communications shall be:

              If to the Company:

                        Biospherics Incorporated
                        12051 Indian Creek Court
                        Beltsville, MD  20705
                        Telecopy:  301-210-4908
                        Attention:  Dr. Gilbert V. Levin

                                  with a copy to:

                        Smith, Somerville & Case, L.L.C.
                        Attorneys At Law
                        100 Light Street
                        Baltimore, MD  21202
                        Telecopy:  410-385-8060
                        Attention:  James Baker, Esq.

and if to the Holder, at such address as Holder shall have provided in 
writing to the Company, or at such other address as each party furnishes by 
notice given in accordance with this Section 9.

    11.  Governing Law: Jurisdiction.  This Warrant shall be governed by and 
construed in accordance with the laws of the State of Delaware applicable to 
contracts made and to be performed in the State of Delaware.  The Company 
irrevocably consents to the jurisdiction of the 

                                      13

<PAGE>

United States federal courts located in the County of New Castle in the State 
of Delaware in any suit or proceeding based on or arising under this Warrant 
and irrevocably agrees that all claims in respect of such suit or proceeding 
may be determined in such courts.  The Company irrevocably waives the defense 
of an inconvenient forum to the maintenance of such suit or proceeding.  The 
Company agrees that a final non-appealable judgment in any such suit or 
proceeding shall be conclusive and may be enforced in other jurisdictions by 
suit on such judgment or in any other lawful manner.

    12.  Miscellaneous.

    (a)  Amendments.  This Warrant and any provision hereof may only be 
amended by an instrument in writing signed by the Company and the Holder.

    (b)  Descriptive Headings.  The descriptive headings of the several 
Sections of this Warrant are inserted for purposes of reference only, and 
shall not affect the meaning or construction of any of the provisions hereof.

    (c)  Cashless Exercise.  Notwithstanding anything to the contrary 
contained in this Warrant, this Warrant may be exercised by presentation and 
surrender of this Warrant to the Company at its principal executive offices 
with a written notice of the Holder's intention to effect a cashless 
exercise, including a calculation of the number of shares of Common Stock to 
be issued upon such exercise in accordance with the terms hereof (a "Cashless 
Exercise").  In the event of a Cashless Exercise, in lieu of paying the 
Exercise Price in cash, the Holder shall surrender this Warrant for the 
number of shares of Common Stock determined by multiplying the number of 
Warrant Shares to which it would otherwise be entitled by a fraction, the 
numerator of which shall be the difference between the then current Market 
Price per share of the Common Stock and the Exercise Price, and the 
denominator of which shall be such then current Market Price per share of 
Common Stock.

    (d)  Assignability.  This Warrant shall be binding upon the Company and 
its successors and assigns and shall inure to the benefit of Holder and its 
successors and assigns.  The Holder shall notify the Company upon the 
assignment of this Warrant.

                                 * * * * *

    IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by 
its duly authorized officer.

                                  BIOSPHERICS INCORPORATED

                                  By:  
                                     ------------------------------------

                                  Name:     
                                       ----------------------------------

                                  Title:
                                        ---------------------------------



                                      14

<PAGE>

                         FORM OF EXERCISE AGREEMENT
                                            
       (To be Executed by the Holder in order to Exercise the Warrant)

     The undersigned hereby irrevocably exercises the right to purchase 
____________ of the shares of common stock of Biospherics Incorporated, a 
Delaware corporation (the "Company"), evidenced by the attached Warrant, and 
herewith makes payment of the Exercise Price with respect to such shares in 
full or, if the resale of the Common Stock by the undersigned is not 
currently registered pursuant to an effective registration statement under 
the Securities Act of 1933, as amended, elects to effect a Cashless Exercise 
pursuant to the terms of the Warrant, all in accordance with the conditions 
and provisions of said Warrant.

    (i)  The undersigned agrees not to offer, sell, transfer or otherwise 
dispose of any Common Stock obtained on exercises of the Warrant, except 
under circumstances that will not result in a violation of the Securities Act 
of 1933, as amended, or any state securities laws.

    (ii) The undersigned requests that stock certificates for such shares be 
issued, and a Warrant representing any unexercised portion hereof be issued, 
pursuant to the Warrant in the name of the Holder (or such other person or 
persons indicated below) and delivered to the undersigned (or designee(s) at 
the address (or addresses) set forth below:

Date:
      -------------------------             -------------------------------
                                            Signature of Holder


                                            -------------------------------
                                            Name of Holder (Print)

                                            Address:

                                            -------------------------------

                                            -------------------------------




                                      15

<PAGE>

                             FORM OF ASSIGNMENT
                                           
    FOR VALUE RECEIVED, the undersigned hereby sells, assigns, and transfers 
all rights of the undersigned under the within Warrant, with respect to the 
number of shares of Common Stock covered thereby set forth herein below, to:

Name of Assignee             Address                  No. of Shares
- ----------------             -------                  -------------

, and hereby irrevocably constitutes and appoints _____________________________
as agent and attorney-in-fact to transfer said Warrant on the books of the
within-named corporation, with full power of substitution in the premises.

Date:
      ---------------,---------


In the presence of:

      -------------------------

                                 Name: 
                                       -------------------------------------

                                 Signature:
                                            --------------------------------

                                 Title of Signing Officer or Agent (if any):

                                 -------------------------------------------

                                 Address:

                                            -------------------------------

                                            -------------------------------

                                 Note: The above signature should correspond 
                                       exactly with the name on the face 
                                       of the within Warrant.

                                      16


<PAGE>

                                                                 Exhibit (10.4)
       
                                       EXHIBIT B
                            to Securities Purchase Agreement
                                           

                              REGISTRATION RIGHTS AGREEMENT
                                         
    THIS REGISTRATION RIGHTS AGREEMENT (this "Agreement"), is made as of 
December 12, 1997, by and among Biospherics Incorporated, a Delaware 
corporation (the "Company"), with headquarters located at 12051 Indian Creek 
Court, Beltsville, Maryland, and the undersigned (the "Purchaser").

                                       RECITALS
                                           
    A.   In connection with the Securities Purchase Agreement dated of even 
date herewith by and between the Company and Purchaser (the "Securities 
Purchase Agreement"), the Company has agreed, upon the terms and subject to 
the conditions contained therein, to issue and sell to Purchaser (i) shares 
of the Company's Common Stock, par value $.005 per share (the "Common Stock") 
and (ii) warrants to purchase shares of Common Stock in the form attached as 
Exhibits A-1 and A-2 to the Securities Purchase Agreement.  The shares of 
Common Stock being purchased under the Securities Purchase Agreement are 
referred to herein as the "Common Shares".  The warrants being purchased 
under the Securities Purchase Agreement are referred to herein as the 
"Warrants".  The shares of Common Stock issuable upon the exercise of or 
otherwise pursuant to the Warrants are referred to herein as the "Warrant 
Shares".

    B.   To induce Purchaser to execute and deliver the Securities Purchase 
Agreement, the Company has agreed to provide certain registration rights 
under the Securities Act of 1933, as amended, and the rules and regulations 
thereunder, or any similar successor statute (collectively, the "Securities 
Act"), and applicable state securities laws.

                                      AGREEMENTS
                                           
    NOW THEREFORE, in consideration of the premises and the mutual covenants 
contained herein and other good and valuable consideration, the receipt and 
sufficiency of which are hereby acknowledged, the Company, and Purchaser 
hereby agree as follows:

                                      ARTICLE I
                                     DEFINITIONS
                                           
    1.1  Definitions.  As used in this Agreement, the following terms shall 
have the following meanings:

         (a)  "Purchaser" means Purchaser and any transferees or assignees 
who agree to become bound by the provisions of this Agreement in accordance 
with Article IX hereof.

         (b)  "register," "registered," and "registration" refer to a 
registration effected by preparing and filing a Registration Statement or 
Statements in compliance with the Securities 

                                          1
<PAGE>

Act and pursuant to Rule 415 under the Securities Act or any successor rule 
providing for offering securities on a continuous basis ("Rule 415"), and the 
declaration or ordering of effectiveness of such Registration Statement by 
the United States Securities and Exchange Commission (the "SEC").

         (c)  "Registrable Securities" means the Common Shares and Warrant 
Shares and any shares of capital stock issued or issuable, from time to time 
(with any adjustments), on or in exchange for or otherwise with respect to 
the Common Stock or any other Registrable Securities.

         (d)  "Registration Statement" means a registration statement of the 
Company under the Securities Act.

    1.2  Capitalized Terms.  Capitalized terms used herein and not otherwise 
defined herein shall have the respective meanings set forth in the Securities 
Purchase Agreement.

                                      ARTICLE II
                                     REGISTRATION
                                           
    2.1  Mandatory Registration.  The Company shall prepare, and, on or prior 
to forty-five (45) days after the date of the Closing (the "Filing Date"), 
file with the SEC a Registration Statement on Form S-3 (or, if Form S-3 is 
not then available, on such form of Registration Statement as is then 
available to effect a registration of all of the Registrable Securities, 
subject to the consent of Purchaser (as determined pursuant to Section 11.10 
hereof)) covering the resale of all of the Registrable Securities, which 
Registration Statement, to the extent allowable under the Securities Act and 
the Rules promulgated thereunder (including Rule 416), shall state that such 
Registration Statement also covers such indeterminate number of additional 
shares of Common Stock as may become issuable upon exercise of the Warrants 
pursuant to the so-called anti-dilution provisions thereof.  The Registrable 
Securities included in the Registration Statement shall be allocated among 
Purchaser as set forth in Section 11.11 hereof.  The Registration Statement 
(and each amendment or supplement thereto, and each request for acceleration 
of effectiveness thereof) shall be provided to (and subject to the approval 
of (which approval shall not be unreasonably withheld or denied)) Purchaser 
and their counsel prior to its filing or other submission.

    2.2  Underwritten 0ffering.  If any offering pursuant to a Registration 
Statement pursuant to Section 2.1 hereof involves an underwritten offering, 
Purchaser who hold a majority in interest of the Registrable Securities 
subject to such underwritten offering shall have the right to select a total 
of one firm of legal counsel to represent Purchaser and an investment banker 
or bankers and manager or managers to administer the offering, which 
investment banker or bankers or manager or managers shall be reasonably 
satisfactory to the Company.

    2.3  Payments by the Company.  The Company shall cause the registration 
statement to become effective as soon as practicable, but in no event later 
than the ninetieth (90th) day following the date of the Closing (the 
"Registration Deadline").  If (i) the registration statement(s) covering the 
Registrable Securities required to be filed by the Company pursuant to 
Section 2.1 hereof is not declared effective by the SEC on or before the 
Registration Deadline, or 

                                          2
<PAGE>


(ii) after the registration statement has been declared effective by the SEC, 
sales of all the Registrable Securities (including any Registrable Securities 
required to be registered pursuant to Section 3.2 hereof) cannot be made 
pursuant to the registration statement (by reason of a stop order or the 
Company's failure to update the registration statement or any other reason 
outside the control of Purchaser) or (iii) the Common Stock is not listed or 
included or quotation on the NASDAQ National Market, NASDAQ SmallCap Market, 
the New York Stock Exchange or the American Stock Exchange after being so 
listed or included for quotation, then the Company will make payments to 
Purchaser in such amounts and at such times as shall be determined pursuant 
to this Section 2.3 as partial relief for the damages to Purchaser by reason 
of any such delay in or reduction of their ability to sell the Registrable 
Securities (which remedy shall not be exclusive of any other remedies 
available at law or in equity).  In such event, the Company shall pay to 
Purchaser an amount equal to (i) (A) .02 times (B) the aggregate purchase 
price of the Common Shares and Warrants held by Purchaser (including, without 
limitation, Warrants that have been converted into Warrant Shares) times (ii) 
the sum of:  (A) the number of months (prorated per day for partial months) 
following the Registration Deadline prior to the date the Registration 
Statement filed pursuant to Section 2.1 is declared effective by the SEC plus 
(B) the number of months (prorated per day for partial months) following the 
Registration Deadline but prior to the termination of the Registration 
Periods that sales cannot be legally made pursuant to the Registration 
Statement after the Registration Statement has been declared effective plus 
(c) the number of months (prorated per day for partial months) that the 
Common Stock is not listed or included for quotations on the NASDAQ National 
Market, NASDAQ SmallCap Market, New York Stock Exchange, or American Stock 
Exchange or that trading thereon is halted after the Registration Statement 
has been declared effective.  Such amounts shall be paid in cash. Payments of 
cash pursuant hereto shall be made within five (5) days after the end of each 
period that gives rise to such obligation, provided that, if any such period 
extends for more than thirty (30) days, payments shall be made for each such 
thirty (30) day period within five (5) days after the end of such thirty (30) 
day period.

    2.4  Piggy-Back Registrations.  If at any time prior to the expiration of 
the Registration Period (as hereinafter defined) the Company shall file with 
the SEC a Registration Statement relating to an offering for its own account 
or the account of others under the Securities Act of any of its equity 
securities (other than on Form S-4 or Form S-8 or their then equivalents 
relating to equity securities to be issued solely in connection with any 
acquisition of any entity or business or equity securities issuable in 
connection with stock option or other employee benefit plans), then the 
Company shall send to Purchaser, who has a right to have Registrable 
Securities covered by a Registration Statement pursuant to this Agreement 
written notice of such determination and, if within fifteen (15) days after 
the date of such notice, Purchaser shall so request in writing, the Company 
shall include in such Registration Statement all or any part of the 
Registrable Securities Purchaser requests to be registered, except that if, 
in connection with any underwritten public offering for the account of the 
Company the managing underwriters) thereof shall impose a limitation on the 
number of shares of Common Stock which may be included in the Registration 
Statement because, in such underwriter(s)'judgment, marketing or other 
factors dictate such limitation is necessary to facilitate public 
distribution, then the Company shall be obligated to include in such 
Registration Statement only such limited portion of the Registrable 
Securities with respect to which Purchaser has requested inclusion hereunder 
as the underwriter shall permit.  Any exclusion of Registrable Securities 
shall be made pro rata among Purchaser seeking to include Registrable 
Securities, in proportion to the number of Registrable Securities sought to 

                                          3
<PAGE>


be included by Purchaser; provided, however, that the Company shall not 
exclude any Registrable Securities unless the Company has first excluded all 
outstanding securities, the holders of which are not entitled to inclusion of 
such securities in such Registration Statement or are not entitled to pro 
rata inclusion with the Registrable Securities; and provided, further, 
however, that, after giving effect to the immediately preceding proviso, any 
exclusion of Registrable Securities shall be made pro rata with holders of 
other securities having the right to include such securities in the 
Registration Statement.  No right to registration of Registrable Securities 
under this Section 2.4 shall be construed to limit any registration required 
under Section 2.1 or 3.2 hereof. If an offering in connection with which 
Purchaser is entitled to registration under this Section 2.4 is an 
underwritten offering, then Purchaser whose Registrable Securities are 
included in such Registration Statement shall, unless otherwise agreed by the 
Company, offer and sell such Registrable Securities in an underwritten 
offering using the same underwriter or underwriters and, subject to the 
provisions of this Agreement, on the same terms and conditions as other 
shares of Common Stock included in such underwritten offering.

    2.5  Eligibility for Form S-3.  The Company represents and warrants that 
it meets the requirements for the use of Form S-3 for registration of the 
re-sale by Purchaser of the Registrable Securities.  The Company covenants 
and agrees that throughout the Registration Period (as herein defined), the 
Company shall continue to be eligible to use Form S-3 for registration of 
such re-sale and the Company shall file all reports required to be filed by 
the Company with the SEC in a timely manner so as to maintain such 
eligibility for the use of Form S-3.

                                     ARTICLE III
                              OBLIGATIONS OF THE COMPANY
                                           
    In connection with the registration of the Registrable Securities, the 
Company shall have the following obligations:

    3.1  The Company shall prepare promptly and file with the SEC not later 
than the Filing Date the Registration Statement required by Section 2.1, and 
cause such Registration Statement relating to Registrable Securities to 
become effective as soon as practicable after such filing, and keep the 
Registration Statement effective pursuant to Rule 415 at all times until such 
date as is the earlier of (i) the date on which all of the Registrable 
Securities have been sold (and no further Registrable Securities may be 
issued in the future) and (ii) the date on which all of the Registrable 
Securities (in the reasonable opinion of counsel to Purchaser) may be 
immediately sold to the public without registration and without restriction 
as to the number with Registrable Securities to be sold, whether pursuant to 
Rule 144 or otherwise (the "Registration Period").  The Registration 
Statement (including any amendments or supplements thereto and prospectuses 
contained therein and all documents incorporated by reference therein) shall 
not contain any untrue statement of a material fact or omit to state a 
material fact required to be stated therein, or necessary to make the 
statements therein not misleading.

    3.2  The Company shall prepare and file with the SEC such amendments 
(including post- effective amendments) and supplements to a Registration 
Statement and the prospectus used in connection with the Registration 
Statement as may be necessary to keep the Registration Statement effective at 
all times during the Registration Period, and, during such period, comply 

                                          4
<PAGE>

with the provisions of the Securities Act with respect to the disposition of 
all Registrable Securities of the Company covered by the Registration 
Statement until the termination of the Registration Period or, if earlier, 
such time as all of such Registrable Securities have been disposed of in 
accordance with the intended methods of disposition by the seller or sellers 
thereof as set forth in the Registration Statement.  In the event the number 
of shares available under a Registration Statement filed pursuant to this 
Agreement is insufficient to cover all of the Registerable Securities issued 
pursuant to the Securities Purchase Agreement and exercise of the Warrants, 
the Company shall amend the Registration Statement or file a new Registration 
Statement (on the short form available therefor, if applicable), or both, so 
as to cover all of the Registerable Securities, in each case, as soon as 
practicable, but in any event within twenty (20) business days after the 
necessity therefore arises.  The Company shall use its best efforts to cause 
such amendment and/or new Registration Statement to become effective as soon 
as practicable following the filing thereof.  The provisions of Section 2.3 
above shall be applicable with respect to such obligations, with the ninety 
(90) days running from the day after the date on which the Company reasonably 
first determines (or reasonably should have determined) the need therefor.

    3.3  The Company shall furnish to Purchaser whose Registrable Securities 
are included in the Registration Statement and its legal counsel (a) promptly 
after the same is prepared and publicly distributed, filed with the SEC, or 
received by the Company, one copy of the Registration Statement and any 
amendment thereto, each preliminary prospectus and prospectus and each 
amendment or supplement thereto, and, in the case of the Registration 
Statement referred to in Section 2.1, each letter written by or on behalf of 
the Company to the SEC or the staff of the SEC, and each item of 
correspondence from the SEC or the staff of the SEC, in each case relating to 
such Registration Statement (other than any portion, if any, thereof which 
contains information for which the Company has sought confidential 
treatment), and (b) such number of copies of a prospectus, including a 
preliminary prospectus, and all amendments and supplements thereto and such 
other documents as Purchaser may reasonably request in order to facilitate 
the disposition of the Registrable Securities owned (or to be owned) by 
Purchaser.

    3.4  The Company shall use reasonable efforts to (a) register and qualify 
the Registrable Securities covered by the Registration Statement under 
securities laws of such jurisdictions in the United States as Purchaser who 
holds (or has the right to hold) Registrable Securities being offered 
reasonably requests, (b) prepare and file in those jurisdictions such 
amendments (including post-effective amendments) and supplements to such 
registrations and qualifications as may be necessary to maintain the 
effectiveness thereof during the Registration Period, (c) take such other 
actions as may be necessary to maintain such registrations and qualifications 
in effect at all times during the Registration Period, and (d) take all other 
actions reasonably necessary or advisable to qualify the Registrable 
Securities for sale in such jurisdictions; provided, however, that the 
Company shall not be required in connection therewith or as a condition 
thereto to (i) qualify to do business in any jurisdiction where it would not 
otherwise be required to qualify but for this Section 3.4, (ii) subject 
itself to general taxation in any such jurisdiction, (iii) file a general 
consent to service of process in any such jurisdiction, (iv) provide any 
undertakings that cause the Company material expense or burden, or (v) make 
any change in its charter or by-laws, which in each case the board of 
directors of the Company determines to be contrary to the best interests of 
the Company and its stockholders.

                                          5
<PAGE>

    3.5  In the event Purchaser who hold a majority in interest of the 
Registrable Securities being offered in an offering pursuant to a 
Registration Statement or any amendment or supplement thereto under Section 
2.1 or 3.2 hereof select underwriters for the offering, the, Company shall 
enter into and perform its obligations under an underwriting agreement, in 
usual and customary form, including, without limitation, customary 
indemnification and contribution obligations. with the underwriters of such 
offering.

    3.6  As soon as practicable after becoming aware of such event, the 
Company shall notify (by telephone and also by facsimile and reputable 
overnight courier) Purchaser of the happening of any event, of which the 
Company has knowledge, as a result of which the prospectus included in the 
Registration Statement, as then in effect, includes an untrue statement of a 
material fact or omission to state a material fact required to be stated 
therein or necessary to make the statements therein not misleading, and use 
its best efforts promptly (but in any event within five (5) days) to prepare 
a supplement or amendment to the Registration Statement to correct such 
untrue statement or omission, and deliver such number of copies of such 
supplement or amendment to Purchaser as Purchaser may reasonably request.

    3.7  The Company shall use its best efforts to prevent the issuance of 
any stop order or other suspension of effectiveness of a Registration 
Statement, and, if such an order is issued, to obtain the withdrawal of such 
order at the earliest practicable time and to notify (by telephone and also 
by facsimile and reputable overnight carrier) Purchaser who holds Registrable 
Securities being sold (or, in the event of an underwritten offering, the 
managing underwriters) of the issuance of such order and the resolution 
thereof.

    3.8  The Company shall permit a single firm of counsel designated by 
Purchaser to review the Registration Statement and all amendments and 
supplements thereto (as well as all requests for acceleration or 
effectiveness thereof) a reasonable period of time prior to their filing with 
the SEC, and not file any document in a form to which such counsel reasonably 
objects and will not request acceleration of the Registration Statement 
without prior notice to such counsel.  The sections of the Registration 
Statement covering information with respect to the Investors, the Investors' 
beneficial ownership of securities of the Company or the Investors' intended 
method of disposition of the Registerable Securities shall conform to the 
information provided to the Company by each of the Investors.

    3.9  The Company shall make generally available to its security holders 
as soon as practical, but not later than ninety (90) days after the close of 
the period covered thereby, an earnings statement (in form complying with the 
provisions of Rule 158 under the Securities Act) covering a twelve-month 
period beginning not later than the first day of the Company's fiscal quarter 
next following the effective date of the Registration Statement.

    3.10 At the request of Purchaser in connection with any underwritten 
offer hereunder, the Company shall furnish, on the date of effectiveness of 
the Registration Statement and thereafter from time to time on such dates as 
Purchaser may reasonably request (a) an opinion, dated as of such applicable 
date, from counsel representing the Company addressed to Purchaser and in 
form, scope and substances as is customarily given in an underwritten public 
offering and (b) a letter, dated as of such applicable date, from the 
Company's independent certified public 

                                          6
<PAGE>


accountants addressed to Purchaser and in form, scope and substance as 
customarily given to underwriters in an underwritten public offering.

    3.11 The Company shall make available for inspection during the 
Registration Period by (i) Purchaser, (ii) any underwriter participating in 
any disposition pursuant to the Registration Statement, (iii) one firm of 
attorneys and one firm of accountants retained by Purchaser, and (iv) one 
firm of attorneys retained by all such underwriters (collectively, the 
"Inspectors") all pertinent financial and other records, and pertinent 
corporate documents and properties of the Company (collectively, the 
"Records"), as shall be reasonably deemed necessary by each Inspector and 
cause the Company's officers, directors and employees to supply all 
information which any Inspector may reasonably request; provided, however, 
that each Inspector shall hold in confidence and shall not make any 
disclosure (except to Purchaser) of any Record or other information which the 
Company determines in good faith to be confidential, and of which 
determination the Inspectors are so notified in writing, unless (a) the 
disclosure of such Records is necessary to avoid or correct a misstatement or 
omission in any Registration Statement, (b) the release of such Records is 
ordered pursuant to a subpoena or other order from a court or government body 
of competent jurisdiction, or is otherwise required by applicable law or 
legal process or (c) the information in such Records has been made generally 
available to the public other than by disclosure in violation of this or any 
other agreement (to the knowledge of Purchaser).  The Company shall not be 
required to disclose any confidential information in such Records to any 
Inspector until and unless such Inspector shall have entered into 
confidentiality agreements (in form and reasonable substance satisfactory to 
the Company) with the Company with respect thereto, substantially in the form 
of this Section 3.11.  Purchaser agrees that it shall, upon learning that 
disclosure of such Records is sought in or by a court or governmental body of 
competent jurisdiction or through other means, give prompt notice to the 
Company and allow the Company, at its expense, to undertake appropriate 
action to prevent disclosure of, or to obtain a protective order for, the 
Records deemed confidential.  Nothing herein (or in any other confidentiality 
agreement between the Company and Purchaser) shall be deemed to limit 
Purchaser's ability to sell Registrable Securities in a manner which is 
consistent with applicable laws and regulations.

    3.12 The Company shall hold in confidence and not make any disclosure of 
information concerning Purchaser provided to the Company unless (a) 
disclosure of such information is necessary to comply with federal or state 
securities laws, (b) the disclosure of such information is necessary to avoid 
or correct a misstatement or omission in any Registration Statement, (c) the 
release of such information is ordered pursuant to a subpoena or other order 
from a court or governmental body of competent jurisdiction or is otherwise 
required by applicable law or legal process, (d) such information has been 
made generally available to the public other than by disclosure in violation 
of this or any other agreement (to the knowledge of the Company), or (e) 
Purchaser consents to the form and content of any such disclosure.  The 
Company agrees that it shall, upon learning that disclosure of such 
information concerning Purchaser is sought in or by a court or governmental 
body of competent jurisdiction or through other means, give prompt notice to 
Purchaser prior to making such disclosure, and allow Purchaser, at its 
expense, to undertake appropriate action to prevent disclosure of, or to 
obtain a protective order for, such information.

                                          7
<PAGE>


    3.13 For so long as Purchaser owns any of the Securities or three (3) 
years from the Closing Date, whichever is sooner, the Company shall cause the 
listing and the continuation of listing of all the Registrable Securities 
covered by the Registration Statement on the NASDAQ National Market System 
and cause the Registrable Securities to be quoted or listed on each 
additional national securities exchange or quotation system upon which the 
Common Stock is then listed or quoted.

    3.14 The Company shall provide a transfer agent and registrar, which may 
be a single entity, for the Registrable Securities not later than the 
effective date of the Registration Statement.

    3.15 The Company shall cooperate with Purchaser who hold Registrable 
Securities being offered and the managing underwriter or underwriters, if 
any, to facilitate the timely preparation and delivery of certificates (not 
bearing any restrictive legends) representing Registrable Securities to be 
offered pursuant to the Registration Statement and enable such certificates 
to be in such denominations or amounts, as the case may be, as the managing 
underwriter or underwriters, if any, or Purchaser may reasonably request and 
registered in such names as the managing underwriter or underwriters, if any, 
or Purchaser may request, and, within one (1) business days after a 
Registration Statement which includes Registrable Securities is ordered 
effective by the SEC, the Company shall cause legal counsel selected by the 
Company to deliver, to the transfer agent for the Registrable Securities 
(with copies to Purchaser whose Registrable Securities are included in such 
Registration Statement) an instruction in the form attached hereto as Exhibit 
1 and an opinion of such counsel in the form attached hereto as Exhibit 2.

    3.16 At the request of Purchaser, the Company shall promptly prepare and 
file with the SEC such amendments (including post-effective amendments) and 
supplements to a Registration Statement and the prospectus used in connection 
with the Registration Statement as may be necessary in order to change the 
plan of distribution set forth in such Registration Statement.

    3.17 The Company shall comply with all applicable laws related to a 
Registration Statement and offering and sale of securities and all applicable 
rules and regulations of governmental authorities in connection therewith 
(including, without limitation, the Securities Act and the Securities 
Exchange Act of 1934, as amended, and the rules and regulations promulgated 
by the Commission).

    3.18 The Company shall take all such other actions as Purchaser or the 
underwriters, if any, reasonably request in order to expedite or facilitate 
the disposition of such Registrable Securities.

    3.19 From and after the date of this Agreement, the Company shall not, 
and shall not agree to, allow the holders of any securities of the Company to 
include any of their securities in any Registration Statement or any 
amendment or supplement thereto under Section 2.1 or 3.2 hereof without the 
consent of the holders of a majority of the Registrable Securities.

                                          8
<PAGE>

                                      ARTICLE IV
                               OBLIGATIONS OF PURCHASER
                                           
    In connection with the registration of the Registrable Securities, 
Purchaser shall have the following obligations:

    4.1  Purchaser shall furnish to the Company such information regarding 
itself, the Registrable Securities held by it and the intended method of 
disposition of the Registrable Securities held by it as shall be reasonably 
required to effect the registration of such Registrable Securities and shall 
execute such documents in connection with such registration as the Company 
may reasonably request.  At least ten (10) business days prior to the first 
anticipated filing date of the Registration Statement, the Company shall 
notify Purchaser of the information the Company requires from Purchaser.

    4.2  Purchaser, by such Purchaser's acceptance of the Registrable 
Securities, agrees to cooperate with the Company as reasonably requested by 
the Company in connection with the preparation and filing of the Registration 
Statements hereunder, unless Purchaser has notified the Company in writing of 
such Purchaser's election to exclude all of Purchaser's Registrable 
Securities from the Registration Statement.

    4.3  Purchaser whose Registrable Securities are included in a 
Registration Statement understands that the Securities Act may require 
delivery of a prospectus relating thereto in connection with any sale thereof 
pursuant to such Registration Statement, and Purchaser shall use its 
reasonable efforts to comply with the applicable prospectus delivery 
requirements of the Securities Act in connection with any such sale.

    4.4  Purchaser agrees that, upon receipt of written notice from the 
Company of the happening of any event of the kind described in Section 3.6, 
such Purchaser will immediately discontinue disposition of Registrable 
Securities pursuant to the Registration Statement covering such Registrable 
Securities until such Purchaser's receipt of the copies of the supplemented 
or amended prospectus contemplated by Section 3.6 and, if so directed by the 
Company, Purchaser shall deliver to the Company (at the expense of the 
Company) or destroy (and deliver to the Company a certificate of destruction) 
all copies in Purchaser's possession (other than a limited number of 
permanent file copies), of the prospectus covering such Registrable 
Securities current at the time of receipt of such notice.

    4.5  Without limiting Purchaser's rights under Section 2.1 or 3.2 hereof, 
no Purchaser may participate in any underwritten distribution hereunder 
unless Purchaser (a) agrees to sell Purchaser's Registrable Securities on the 
basis provided in any underwriting arrangements in usual and customary form 
entered into by the Company, (b) completes and executes all questionnaires, 
powers of attorney, indemnities, underwriting agreements and other documents 
reasonably required under the terms of such underwriting arrangements, and 
(c) agrees to pay its pro rata share of all underwriting discounts and 
commissions and any expenses in excess of those payable by the Company 
pursuant to Article V.

                                          9
<PAGE>
 
                                      ARTICLE V
                               EXPENSES OF REGISTRATION
                                           
    All expenses, other than underwriting discounts and commissions, incurred 
in connection with registrations, filings or qualifications pursuant to 
Articles II and III, including, without limitation, all registration, listing 
and qualification fees, printers and accounting fees, the fees and 
disbursements of counsel for the Company, and the reasonable fees and 
disbursements of one firm of counsel selected by Purchaser pursuant to 
Section 2.2, hereof shall be borne by the Company.

                                      ARTICLE VI
                                   INDEMNIFICATION
                                           
    In the event any Registrable Securities are included in a Registration 
Statement under this Agreement:

    6.1  To the extent permitted by law, the Company will indemnify, hold 
harmless and defend (a) Purchaser who holds such Registrable Securities, (b) 
each underwriter of Registrable Securities and (c) the directors, officers, 
partners, members, employees, agents and persons who control Purchaser within 
the meaning of Section 15 of the Securities Act or Section 20 of the 
Securities Exchange Act of 1934, as amended (the "Exchange Act"), if any, 
(each, an "Indemnified Person"), against any joint or several losses, claims, 
damages, liabilities or expenses (collectively, together with actions, 
proceedings or inquiries by any regulatory or self-regulatory organization, 
whether commenced or threatened, in respect thereof, "Claims") to which any 
of them may become subject insofar as such Claims arise out of or are based 
upon: (i) any untrue statement or alleged untrue statement of a material fact 
in a Registration Statement or the omission or alleged omission to state 
therein a material fact required to be stated or necessary to make the 
statements therein not misleading, (ii) any untrue statement or alleged 
untrue statement of a material fact contained in any preliminary prospectus 
if used prior to the effective date of such Registration Statement, or 
contained in the final prospectus (as amended or supplemented, if the Company 
files any amendment thereof or supplement thereto with the SEC) or the 
omission or alleged omission to state therein any material fact necessary to 
make the statements made therein, in light of the circumstances under which 
the statements therein were made, not misleading, or (iii) any violation or 
alleged violation by the Company of the Securities Act, the Exchange Act, any 
other law, including, without limitation, any state securities law, or any 
rule or regulation thereunder relating to the offer or sale of the 
Registrable Securities (the matters in the foregoing clauses (i) through 
(iii) being, collectively, "Violations").  Subject to the restrictions set 
forth in Section 6.3 with respect to the number of legal counsel, the Company 
shall reimburse Purchaser, each such underwriter and controlling person, and 
each such other Indemnified Person, promptly as such expenses are incurred 
and are due and payable, for any reasonable legal fees or other reasonable 
expenses incurred by them in connection with investigating or defending any 
such Claim.  Notwithstanding anything to the contrary contained herein, the 
indemnification agreement contained in this Section 6.1: (x) shall not apply 
to an Indemnified Person with respect to a Claim arising out of or based upon 
a Violation which occurs in reliance upon and in conformity with information 
furnished in writing to the Company by such Indemnified Person expressly for 
use in the Registration Statement or any such amendment thereof or supplement 
thereto; (y) shall not apply to amounts paid in settlement of any Claim if 
such settlement is effected without the prior written consent of the Company, 
which consent shall not be unreasonably withheld; and (z) with respect to any 
preliminary prospectus, shall not inure to the benefit of any Indemnified 
Person if the untrue statement or omission of material fact contained in the 
preliminary prospectus was corrected on a timely basis in the prospectus, as 
then amended or supplemented, if such corrected prospectus was timely made 
available by the Company pursuant to Section 3.3 hereof, and the Indemnified 
Person was promptly advised in writing not to use the incorrect prospectus 
prior to the use giving rise to a Violation and such Indemnified 

                                          10
<PAGE>

Person, notwithstanding such advice, used it.  Such indemnity shall remain in 
full force and effect regardless of any investigation made by or on behalf of 
the Indemnified Person and shall survive the transfer of the Registrable 
Securities by Purchaser pursuant to Article IX.

    6.2  In connection with any Registration Statement in which Purchaser is 
participating, Purchaser agrees to indemnify, hold harmless and defend, to 
the same extent and in the same manner set forth in Section 6. 1, the 
Company, each of its directors, each of its officers who signs the 
Registration Statement, its employees, agents and persons, if any, who 
control the Company within the meaning of Section 15 of the Securities Act or 
Section 20 of the Exchange Act, and any other stockholder selling securities 
pursuant to the Registration Statement, together with its directors, officers 
and members, and any person who controls such stockholder or underwriter 
within the meaning of the Securities Act or the Exchange Act (such an 
"Indemnified Party"), against any Claim to which any of them may become 
subject, under the Securities Act, the Exchange Act or otherwise, insofar as 
such Claim arises out of or is based upon any Violation, in each case to the 
extent (and only to the extent) that such Violation occurs in reliance upon 
and in conformity with written information furnished to the Company by 
Purchaser expressly for use in connection with such Registration Statement; 
and subject to Section 6.3 Purchaser will reimburse any legal or other 
expenses (promptly as such expenses are incurred and are due and payable) 
reasonably incurred by them in connection with investigating or defending any 
such Claim; provided, however, that the indemnity agreement contained in this 
Section 6.2 shall not apply to amounts paid in settlement of any Claim if 
such settlement is effected without the prior written consent of Purchaser, 
which consent shall not be unreasonably withheld; provided, further, however, 
that Purchaser shall be liable under this Agreement (including this Section 
6.2 and Article VII) for only that amount as does not exceed the net proceeds 
actually received by Purchaser as a result of the sale of Registrable 
Securities pursuant to such Registration Statement.  Such indemnity shall 
remain in full force and effect regardless of any investigation made by or on 
behalf of such Indemnified Party and shall survive the transfer of the 
Registrable Securities by Purchaser pursuant to Article IX.  Notwithstanding 
anything to the contrary contained herein, the indemnification agreement 
contained in this Section 6.2 with respect to any preliminary prospectus 
shall not inure to the benefit of any Indemnified Party if the untrue 
statement or omission of material fact contained in the preliminary 
prospectus was corrected on a timely basis in the prospectus, as then amended 
or supplemented, and the Indemnified Party failed to utilize such corrected 
prospectus.

    6.3  Promptly after receipt by an Indemnified Person or Indemnified Party 
under this Article VI of notice of the commencement of any action (including 
any governmental action), such Indemnified Person or Indemnified Party shall, 
if a Claim in respect thereof is to made against any indemnifying party under 
this Article VI, deliver to the indemnifying party a written notice of the 
commencement thereof, and the indemnifying party shall have the right to 
participate in, and, to the extent the indemnifying party so desires, jointly 
with any other indemnifying party similarly noticed, to assume control of the 
defense thereof with counsel mutually satisfactory to the indemnifying party 
and the Indemnified Person or the Indemnified Party, as the case may be; 
provided, however, that such indemnifying party shall diligently pursue such 
defense and that such indemnifying party shall not be entitled to assume such 
defense and an Indemnified Person or Indemnified Party shall have the right 
to retain its own counsel with the fees and expenses to be paid by the 
indemnifying party, if the representation by such counsel of the Indemnified 
Person or Indemnified Party and the indemnifying party would 

                                          11
<PAGE>

be inappropriate due to actual or potential conflicts of interest between 
such Indemnified Person or Indemnified Party and any other party represented 
by such counsel in such proceeding or the actual or potential defendants in, 
or targets of, any such action include both the Indemnified Person or the 
Indemnified Party and any such Indemnified Person or Indemnified Party 
reasonably determines that there may be legal defenses available to such 
Indemnified Person or Indemnified Party which are different from or in 
addition to those available to such indemnifvin2 party.  The indemnifying 
party shall pay for only one separate firm of legal counsel for the 
Indemnified Persons or the Indemnified Parties, as applicable, and such legal 
counsel shall be selected by Purchaser holding a majority-in-interest of the 
Registrable Securities included in the Registration Statement to which the 
Claim relates (with the approval of Purchaser if they hold Registrable 
Securities included in such Registration Statement), if Purchaser are 
entitled to indemnification hereunder, or by the Company, if the Company is 
entitled to indemnification hereunder, as applicable.  The failure to deliver 
written notice to the indemnifying party within a reasonable time of the 
commencement of any such action shall not relieve such indemnifying party of 
any liability to the Indemnified Person or Indemnified Party under this 
Article VI, except to the extent that the indemnifying party is actually 
prejudiced in its ability to defend such action.  The indemnification 
required by this Article VI shall be made by periodic payments of the amount 
thereof during the course of the investigation or defense, as such expense, 
loss, damage or liability is incurred and is due and payable.

                                     ARTICLE VII
                                     CONTRIBUTION
                                           
    To the extent any indemnification by an indemnifying party is prohibited 
or limited by law, the indemnifying party agrees to make the maximum 
contribution with respect to any amounts for which it would otherwise be 
liable under Article VI to the fullest extent permitted by law; provided, 
however, that (i) no contribution shall be made under circumstances where the 
maker would not have been liable for indemnification under the fault 
standards set forth in Article VI, (ii) no person guilty of fraudulent 
misrepresentation (within the meaning of Section 11(f) of the Securities Act) 
shall be entitled to contribution from any person of Registrable Securities 
who was not guilty of such fraudulent misrepresentation, and (iii) 
contribution (together with any indemnification or other obligations under 
this Agreement) by any seller of Registrable Securities shall be limited in 
amount to the net amount of proceeds received by such seller from the sale of 
such Registrable Securities.

                                     ARTICLE VIII
                            REPORTS UNDER THE EXCHANGE ACT
                                           
    With a view to making available to Purchaser the benefits of Rule 144 
promulgated under the Securities Act or any other similar rule or regulation 
of the SEC that may at any time permit Purchaser to sell securities of the 
Company to the public without registration ("Rule 144"), the Company agrees, 
during the Registration Period and for one year thereafter, to:
    
    8.1  Make and keep public information available, as those terms are 
understood and defined in Rule 144;

                                          12
<PAGE>


    8.2  File with the SEC in a timely manner and make and keep available all 
reports and other documents required of the Company under the Securities Act 
and the Exchange Act so long as the Company remains subject to such 
requirements (it being understood that nothing herein shall limit the 
Company's obligations under Section 4.3 of the Securities Purchase Agreement) 
and the filing and availability of such reports and other documents is 
required for the applicable provisions of Rule 144; and

    8.3  Furnish to Purchaser so long as Purchaser holds Warrants or 
Registrable Securities, promptly upon request, (i) a written statement by the 
Company that it has complied with the reporting requirements of Rule 144, the 
Securities Act and the Exchange Act, (ii) a copy of the most recent annual or 
quarterly report of the Company and such other reports and documents so filed 
by the Company, and (iii) such other information as may be reasonably 
requested to permit Purchaser to sell such securities pursuant to Rule 144 
without registration.

                                      ARTICLE IX
                          ASSIGNMENT OF REGISTRATION RIGHTS
                                           
    The rights of Purchaser hereunder, including the right to have the 
Company register Registrable Securities pursuant to this Agreement, shall be 
automatically assignable by Purchaser to any transferee of all or any portion 
of the Warrants or the Registrable Securities if:  (a) Purchaser agrees in 
writing with the transferee or assignee to assign such rights, and a copy of 
such agreement is furnished to the Company within a reasonable time after 
such assignment, (b) the Company is, within a reasonable time after such 
transfer or assignment, furnished with written notice of (i) the name and 
address of such transferee or assignee, and (ii) the securities with respect 
to which such registration rights are being transferred or assigned, (c) 
following such transfer or assignment, the further disposition of such 
securities by the transferee or assignee is restricted under the Securities 
Act or applicable state securities laws, (d) at or before the time the 
Company receives the written notice contemplated by clause (ii) of this 
sentence, the transferee or assignee agrees in writing for the benefit of the 
Company to be bound by all of the provisions contained herein, and (e) such 
transfer shall have been made in accordance with the applicable requirements 
of the Securities Purchase Agreement.  Notwithstanding any provision to the 
contrary herein, Purchaser shall have the right to pledge the Registrable 
Securities and in the event that the pledgee forecloses on the pledged 
Registrable Securities, then the pledgee shall be entitled to exercise the 
rights of the Purchaser hereunder.

                                      ARTICLE X
                           AMENDMENT OF REGISTRATION RIGHTS
                                           
    Provisions of this Agreement may be amended and the observance thereof 
may be waived (either generally or in a particular instance and either 
retroactively or prospectively), only with written consent of the Company and 
Purchaser who hold a majority interest of the Registrable Securities 
(determined as if all Warrants then outstanding had been exercised for 
Warrant Shares).  Any amendment or waiver effected in accordance with this 
Article X shall be binding upon Purchaser and the Company.  Notwithstanding 
the foregoing, no amendment or waiver shall retroactively affect Purchaser 
without its consent or prospectively adversely affect Purchaser who no longer 
owns any Warrants or Registrable Securities without its consent.  

                                          13
<PAGE>


Neither Article VI nor Article VII hereof may be amended or waived in a 
manner adverse to Purchaser without its consent.

                                      ARTICLE XI
                                    MISCELLANEOUS
                                           
    11.1 A person or entity is deemed to be a holder of Registrable 
Securities whenever such person or entity owns of record such Registrable 
Securities.  If the Company receives conflicting instructions, notices or 
elections from two or more persons or entities with respect to the same 
Registrable Securities, the Company shall act upon the basis of instructions, 
notice or election received from the registered owner of such Registrable 
Securities.

    11.2 Any notices herein required or permitted to be given shall be in 
writing and may be personally served or delivered by courier (including a 
recognized overnight delivery service) or by confirmed telecopy, and shall be 
deemed delivered at the time and date of receipt (which shall include 
telephone line facsimile transmission).  The addresses for such 
communications shall be:

              If to the Company:
              
              Biospherics Incorporated
              12051 Indian Creek Court
              Beltsville, MD  20705
              Telecopy:  301-210-4908/09
              Attention:  Dr. Gilbert V. Levin
              
                   with a copy to:
              
              Smith, Somerville & Case, L.L.C.
              Attorneys At Law
              100 Light Street
              Baltimore, MD  21202
              Telecopy:  410-385-8060
              Attention:  James Baker, Esq.
              
              If to RGC International Investors, LDC:
              
              c/o Rose Glen Capital Management, L.P.
              251 St. Asaphs Road
              Suite 200
              3 Bala Plaza East
              Bala Cynwyd, PA  19004
              Telecopy:  610-617-0570
              Attention:  Wayne D. Bloch
              
                   with a copy to:
              


                                          14
<PAGE>

              Ballard, Spahr, Andrews & Ingersoll
              1735 Market Street
              51st Floor
              Philadelphia, PA  19103
              Telecopy:  215-864-8999
              Attention:  Gerald J. Guarcini, Esq.

and if to Purchaser, at such address as Purchaser shall have provided in 
writing to the Company, or at such other address as each such party furnishes 
by notice given in accordance with this Section 11.2.

    11.3 Failure of any party to exercise any right or remedy under this 
Agreement or otherwise, or delay by a party in exercising such right or 
remedy, shall not operate as a waiver thereof.

    11.4 This Agreement shall be governed by and construed in accordance with 
the laws of the State of Delaware applicable to contracts made and to be 
performed in the State of Delaware.  The Company irrevocably consents to the 
jurisdiction of the federal courts located in the state of Delaware and the 
state courts of the State of Delaware located in the County of New Castle in 
the State of Delaware in any suit or proceeding based on or arising under 
this Agreement and irrevocably agrees that all claims in respect of such suit 
or proceeding may be determined in such courts.  The Company irrevocably 
waives the defense of an inconvenient forum to the maintenance of such suit 
or proceeding. The parties hereto further agree that service of process upon 
the parties hereto mailed by first class mail shall be deemed in every 
respect effective service of process upon each such party in any such suit or 
proceeding.  Nothing herein shall affect either party's right to serve 
process in any other manner permitted by law.  The parties hereto agree that 
a final non-appealable judgment, in any such suit or proceeding shall be 
conclusive and may be enforced in other jurisdictions by suit on such 
judgment or in any other lawful manner.

    11.5 This Agreement, the Warrants and the Securities Purchase Agreement 
(including all schedules and exhibits thereto and all certificates and 
opinions required thereby) constitute the entire agreement among the parties 
hereto with respect to the subject matter hereof and thereof.  There are no 
restrictions, promises, warranties or undertakings, other than those set 
forth or referred to herein and therein.  This Agreement, the Warrants and 
the Securities Purchase Agreement supersede all prior agreements and 
understandings among the parties hereto with respect to the subject matter 
hereof and thereof.

    11.6 Subject to the requirements of Article IX hereof, this Agreement 
shall inure to the benefit of and be binding upon the successors and 
permitted assigns of each of the parties hereto.

    11.7 The headings in this Agreement are for convenience of reference only 
and shall not limit or otherwise affect the meaning hereof.

    11.8 This Agreement may be executed in two or more counterparts, each of 
which shall be deemed an original but all of which shall constitute one and 
the same agreement.  This Agreement, once executed by a party, may be 
delivered to the other party hereto, by facsimile 

                                          15
<PAGE>

transmission of a copy of this Agreement bearing the signature of the party 
so delivering this Agreement.

    11.9 Each party shall do and perform, or cause to be done and performed, 
all such further acts and things, and shall execute and deliver all such 
other agreements, certificates, instruments and documents, as the other party 
may reasonably request in order to carry out the intent and accomplish the 
purposes of this Agreement and the consummation of the transactions 
contemplated hereby.

    11.10     All consents and other determinations to be made by Purchaser 
pursuant to this Agreement shall be made by Purchaser holding a majority of 
the Registrable Securities (determined as if all Warrants then outstanding 
had been exercised for Warrant Shares) held by Purchaser.

    11.11     The initial number of Registrable Securities included on any 
Registration Statement and each increase to the number of Registrable 
Securities included thereon shall be allocated 100% to Purchaser based on the 
number of Registrable Securities held by Purchaser at the time of such 
establishment or increase, as the case may be.  In the event Purchaser shall 
sell or otherwise transfer any of such holder's Registrable Securities, each 
transferee shall be allocated a pro rata portion of the number of Registrable 
Securities included on a Registration Statement for such transferor.  Any 
shares of Common Stock included on a Registration Statement and which remain 
allocated to any person or entity which does not hold any Registrable 
Securities shall be allocated to Purchaser, pro rata based on the number of 
shares of Registrable Securities then held by Purchaser.  Without implication 
that the contrary would otherwise be true, for purposes, of this paragraph, 
all Warrants then outstanding shall be assumed exercised for Warrant Shares.

    11.12     If any provision of this Agreement shall be invalid or 
unenforceable, such invalidity or unenforceability shall not affect the 
validity or enforceability of the remainder of this Agreement.
    
    11.13     The language used in this Agreement will be deemed to be the 
language chosen by the parties to express their mutual intent, and no rules 
of strict construction will be applied against any party.

                                      * * * * *
                                           


                                          16
<PAGE>

    IN WITNESS WHEREOF, the parties have caused this Agreement to be duly 
executed as of the date first above written.

COMPANY:

BIOSPHERICS INCORPORATED

By: _______________________________

Name:    _______________________________

Title:   _______________________________


PURCHASER:

RGC INTERNATIONAL INVESTORS, LDC

By: Rose Glen Capital Management, L.P.
    Investment Manager
    By:  RGC General Partner Corp., as General Partner

By:  _____________________________

Its: ______________________________

                                          17
<PAGE>


                                                                       EXHIBIT 1
                                                                 to Registration
                                                                Rights Agreement

                                         Date
                                           
American Stock Transfer and Trust Co.
6201 15th Avenue, 3rd Floor
Brooklyn, NY  11219

Ladies and Gentlemen:

    This letter shall serve as our irrevocable authorization and direction to 
you (1) to transfer or re-register (or at the holders request to reissue to 
the holder thereof without any restrictive legend) the certificates for the 
shares of Common Stock, par value $.005 per share (the "Common Stock"), of 
Biospherics Incorporated, a Delaware corporation (the "Company"), represented 
by certificate numbers _____ for an aggregate of _____ shares (the 
"Outstanding Shares") of Common Stock presently registered in the name of 
[Name of Investor] (the "Investor") (which shares were previously issued 
pursuant to the Securities Purchase Agreement dated December 12, 1997 (the 
"Agreement") or exercise of the Warrants (as hereinafter defined)), upon 
surrender of such certificates to you, notwithstanding the legend appearing 
on such certificates, and (2) to issue shares (the "Warrant Shares") of the 
Common Stock to or upon the order of the registered holder from time to time 
of the Warrants of the Company (the "Warrants") upon surrender to you of a 
properly completed and duly executed Exercise Agreement and such Warrants 
notwithstanding the legend appearing on such Warrants.  The transfer or 
re-registration of the certificates for the Outstanding Shares by you should 
be made at such time as you are requested to do so by the record holder of 
the Outstanding Shares.  The certificate issued upon such transfer or 
re-registration should be registered in such name as requested by the holder 
of record of the certificate surrendered to you and should not bear any 
legend which would restrict the transfer of the shares represented thereby.  
In addition, you are hereby directed to remove any stop-transfer instruction 
relating to the Outstanding Shares.  Certificates for the shares issued 
pursuant to the Agreement and Warrant Shares should not bear any restrictive 
legend and should not be subject to any stop-transfer restriction.

    Pursuant to applicable securities laws or certain agreements between the 
Company and the Investor, the Investor may be prohibited during certain 
limited periods of time from selling its Outstanding Shares or other shares 
of Common Stock issued pursuant to the Agreement or issuable upon exercise of 
the Warrants under the Registration Statement; provided, however, that such 
Investor may continue to sell such securities pursuant to an exemption from 
registration under the Securities Act of 1933, as amended (the "1933 Act").  
The Company may, during such periods, deliver a notice to you advising you to 
refrain from transferring any Outstanding Shares pursuant to such 
Registration Statement, provided that such notice shall not prohibit the 
transfer of such shares pursuant to an exemption from registration under the 
1933 Act during such periods.

                                          18
<PAGE>

    Contemporaneous with the delivery of this letter, the Company is 
delivering to you a letter of ____________ as to registration of the 
Outstanding Shares and the Conversion Shares under the Securities Act of 
1933, as amended.

    Should you have any questions concerning this matter, please contact me.

                                               Very truly yours,

                                               BIOSPHERICS INCORPORATED



                                               ________________________________
                                               By:
                                               Title:

Enclosures:
cc:  [Name of Investor]


                                          19
<PAGE>

                                                                       EXHIBIT 2
                                                                 to Registration
                                                                Rights Agreement

                                         Date
                                           
American Stock Transfer and Trust Co.
6201 15th Avenue, 3rd Floor
Brooklyn, NY  11219

                             RE: Biospherics Incorporated
                                           
Ladies and Gentlemen:

    We are counsel to Biospherics Incorporated, a Delaware corporation (the 
"Company"), and we understand that [Name of Purchaser] (the "Holder") has 
purchased from the Company (i) shares of the Company's common stock, par 
value $.005 per share (the "Common Stock") and (ii) warrants to purchase 
shares of Common Stock.  Such securities were purchased by the Holder 
pursuant to a Securities Purchase Agreement, dated as of December 12, 1997, 
by and among the Company and the signatories thereto (the "Agreement").  
Pursuant to a Registration Rights Agreement, dated as of December 12, 1997, 
by and among the Company and the signatories thereto (the "Registration 
Rights Agreement"), the Company agreed with the Holder, among other things, 
to register the Registrable Securities (as that term is defined in the 
Registration Rights Agreement) under the Securities Act of 1933, as amended 
(the "Securities Act"), upon the terms provided in the Registration Rights 
Agreement.  In connection with the Company's obligations under the 
Registration Rights Agreement, on ________ ___, 1998, the Company filed a 
Registration Statement on Form S-_____ (File No. 333-_____________) (the 
"Registration Statement") with the Securities and Exchange Commission (the 
"SEC") relating to the Registrable Securities, which names the Holder as a 
selling stockholder thereunder.

    
[Other customary introductory and scope of examination language to be inserted]

    Based on the foregoing, we are of the opinion that the Registrable 
Securities have been registered under the Securities Act.

                [Other appropriate customary language to be included.]
                                           
                                  Very truly yours,
                                           
cc: [Name of Purchaser]


                                          20


<PAGE>
                                                                  Exhibit (99)

                                       For further details, call
                                       Jeffrey W. Church, Executive VP, CFO
                                       Biospherics Incorporated
December 17, 1997                      at (301) 419-3900



                     BIOSPHERICS PLANS HEALTHCARE SUBSIDIARY,
                            RECEIVES PRIVATE FINANCING
                                           
                                           
    Biospherics Incorporated (NASDAQ/BINC), Beltsville, Maryland, today 
announced plans to enter the fast-growing healthcare information and 
management industry.  A newly formed subsidiary approved by the Company's 
shareholders in its May 1997 meeting will provide health information and 
guidance to HMOs, other group health organizations, and self-insured 
employers.  The venture will feature nurse triage, disease management, and 
health risk assessment services.

    The new organization will combine Biospherics' healthcare oriented call 
center operations utilizing technology obtained from Clinical Solutions, 
Incorporated (CSI) of Menlo Park, California.  Biospherics and CSI have 
signed a letter of agreement that provides CSI an equity interest in the 
subsidiary.  The subsidiary will have the benefit of CSI's outstanding staff 
of medical and marketing personnel, and its proprietary algorithm software, 
which will be used by call center nurses to give accurate and fast 
information to callers with health problems.  The CSI algorithm system has 
been evaluated by medical experts as superior to the older and slower 
protocol software.  The two organizations are working out details of the new 
venture pending a final agreement. Commencement of operations is also 
dependent upon the new organization's obtaining permanent financing.  Such 
financing is currently anticipated near the end of the first quarter of 1998.

    To help fund the subsidiary's start-up as well as support Biospherics' 
general working capital and capital expenditure needs including software 
development for future contracts, the Company completed a $3 million private 
offering of units to a single institutional investor.  The Company sold 
375,000 units, each unit consisting of two shares of common stock and two 
warrants with exercise prices of $4.00 and $4.50 per share, respectively.  
The transaction was effected in reliance upon the exemption from securities 
registration afforded by the provisions of Regulation D, as established by 
the U.S. Securities and Exchange Commission (SEC) and the Securities Act of 
1933. The warrants are exercisable for a three-year period after the date of 
closing. Should all the warrants be exercised, the Company will receive an 
additional $3.2 million.  The initial net proceeds from the sale of $3 
million of units will come to approximately $2.7 million.  The Company has 
agreed to file a Registration Statement on Form S-3 with the SEC for the 
resale of all registrable securities covered by this transaction.

    Dr. Gilbert V. Levin, President of Biospherics, said "The capabilities of 
CSI combined with our Company's extensive medical call center experience 
places the new enterprise in the forefront of this dramatically growing 
industry.  The Nation's medical bills now top $1 trillion, and the market is 
wide open for firms who can control costs while improving healthcare."

    Those from CSI joining the new organization will be:  Dennis McShane, 
M.D., Stanford University, principal inventor of the algorithm system, and 
Clinical Professor of Medicine in Immunology at Stanford; Glenn Laffel, M.D., 
University of Miami, Ph.D. from MIT, formerly Senior Attending Physician 
Cardiac Transplantation Program, Director of Quality Care Management at 
Brigham's and Women's Hospital, editor of QUALITY MANAGEMENT IN HEALTH CARE; 
David Hodges, M.D., NYU, M.P.H., Harvard School of Public Health; and Harry 
Harrington, B.A., University of California, Berkeley, and an M.Ed., San Jose 
State University, formerly vice president for business development at 
Healthtrac, Incorporated, and director of strategic marketing for Blue Shield 
of California.  Mr. Harrington is Associate Editor for the AMERICAN JOURNAL 
OF HEALTH PROMOTION.


<PAGE>

    Under its motto, "Technologies for Information and Health," Biospherics' 
mission is to provide guidance and products to improve the quality of life.  
The Firm offers telecommunications and database management information 
systems and proprietary food and medical innovations.

                    Our Internet address is:  http://www.biospherics.com

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