BRISTOL MYERS SQUIBB CO
10-Q, 1999-08-13
PHARMACEUTICAL PREPARATIONS
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                    SECURITIES AND EXCHANGE COMMISSION

                          WASHINGTON, D.C.  20549


                                 FORM 10-Q


          QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                      SECURITIES EXCHANGE ACT OF 1934


               FOR THE QUARTERLY PERIOD ENDED JUNE 30, 1999


                       Commission File Number 1-1136


                       BRISTOL-MYERS SQUIBB COMPANY
          (Exact name of registrant as specified in its charter)



              Delaware                            22-079-0350
     (State or other jurisdiction of     (IRS Employer Identification No.)
     incorporation or organization)



                  345 Park Avenue, New York, N.Y.  10154
                 (Address of principal executive offices)
                         Telephone: (212) 546-4000


Indicate  by  check mark whether the registrant (1) has filed  all  reports
required to be filed by Section 13 or 15(d) of the Securities Exchange  Act
of 1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject  to
such filing requirements for the past 90 days.

Yes  [ X ]            No  [    ]



At  June  30,  1999,  there were 1,986,075,102 shares  outstanding  of  the
Registrant's $.10 par value Common Stock.



<PAGE>

                    BRISTOL-MYERS SQUIBB COMPANY

                         INDEX TO FORM 10-Q

                            June 30, 1999




                                                                Page No.

Part I - Financial Information:

Financial Statements (Unaudited):

Consolidated Balance Sheet - June 30, 1999 and December  31,      2 - 3
1998

Consolidated Statement of Earnings and Comprehensive  Income
for the three and six months ended June 30, 1999 and 1998             4

Consolidated Statement of Cash Flows for the six months ended
June 30, 1999 and 1998                                                5

Management's Discussion and Analysis of Financial  Condition
and Results of Operations                                        6 - 12


Part II - Other Information                                          13

Signatures                                                           14


<PAGE>


PART I  FINANCIAL INFORMATION
- -----------------------------

Item 1.  Financial Statements
- -----------------------------


                     BRISTOL-MYERS SQUIBB COMPANY
                  CONSOLIDATED BALANCE SHEET - ASSETS
             (Unaudited, in millions except share amounts)





                                                 June 30,   December 31,
                                                    1999         1998
Current Assets:
Cash and cash equivalents                          $2,081      $2,244
Time deposits and marketable securities               267         285
Receivables, net of allowances                      3,218       3,190

Finished goods                                      1,402       1,209
Work in process                                       336         236
Raw and packaging materials                           306         428
Inventories                                         2,044       1,873
Prepaid expenses                                    1,048       1,190

  Total Current Assets                              8,658       8,782

Property, Plant and Equipment                       7,613       7,508
Less: Accumulated depreciation                      3,158       3,079

Net Property, Plant and Equipment                   4,455       4,429

Insurance Recoverable                                 504         523
Excess of cost over net tangible assets received
in business acquisitions                            1,590       1,587
Other Assets                                        1,007         951

Total Assets                                      $16,214     $16,272


<PAGE>

                    BRISTOL-MYERS SQUIBB COMPANY
                    CONSOLIDATED BALANCE SHEET -
                LIABILITIES AND STOCKHOLDERS' EQUITY
            (Unaudited, in millions except share amounts)





                                                    June 30,  December 31,
                                                      1999       1998
Current Liabilities:
Short-term borrowings                                 $546       $482
Accounts payable                                     1,373      1,380
Accrued expenses                                     2,160      2,302
Product liability                                      566        877
U.S. and foreign income taxes payable                  722        750

  Total Current Liabilities                          5,367      5,791
Other Liabilities                                    1,460      1,541
Long-Term Debt                                       1,327      1,364

  Total Liabilities                                  8,154      8,696

Stockholders' Equity:
Preferred stock, $2 convertible series:
     Authorized  10 million shares;  issued  and
     outstanding  11,284 in 1999 and  11,684  in         -          -
     1998, liquidation value of $50 per share
Common stock, par value of $.10 per share:
     Authorized   4.5  billion  shares;   issued
     2,190,336,925 in 1999 and 2,188,316,808  in       219        219
     1998
Capital in excess of par value of stock              1,291      1,075
Cumulative translation adjustment                    (783)      (622)
Retained earnings                                   13,705     12,540
                                                    14,432     13,212
Less  cost of treasury stock 204,261,823  common
shares in 1999 and 199,550,532 in 1998               6,372      5,636

Total Stockholders' Equity                           8,060      7,576

Total Liabilities and Stockholders' Equity         $16,214    $16,272


<PAGE>
                    BRISTOL-MYERS SQUIBB COMPANY
                 CONSOLIDATED STATEMENT OF EARNINGS
                      AND COMPREHENSIVE INCOME
    (Unaudited, in millions of dollars except per share amounts)




                                      Three Months       Six Months
                                     Ended June 30,    Ended June 30,
                                     1999      1998     1999     1998
EARNINGS

Net Sales                          $4,920    $4,430   $9,774   $8,876

Expenses:
Cost of products sold               1,361     1,206    2,666    2,358
Marketing,selling,                  1,122     1,034    2,243    2,082
administrative and other
Advertising and product               666       642    1,195    1,213
promotion
Research and development              453       384      876      767
Provision for restructuring             -        76        -      201
Gain on sale of businesses              -      (76)        -    (201)
                                    3,602     3,266    6,980    6,420
Earnings Before Income Taxes        1,318     1,164    2,794    2,456
Provision for income taxes            366       329      775      694

Net Earnings                         $952      $835   $2,019   $1,762

Earnings Per Common Share
   Basic                             $.48      $.42    $1.02     $.89
   Diluted                           $.47      $.41    $1.00     $.87
Average Common Shares
Outstanding (in millions)
   Basic                            1,984     1,987    1,985    1,987
   Diluted                          2,027     2,031    2,027    2,033

Dividends Per Common Share          $.215     $.195     $.43     $.39

COMPREHENSIVE INCOME

Net Earnings                         $952      $835   $2,019   $1,762

Other Comprehensive Income:
Foreign currency translation         (65)        17    (169)     (87)
Tax effect                              3      (11)        8        5

Total Other Comprehensive Income     (62)         6    (161)     (82)

Comprehensive Income                 $890      $841   $1,858   $1,680

<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                   CONSOLIDATED STATEMENT OF CASH FLOWS
                    (Unaudited, in millions of dollars)

                                                     Six Months Ended
                                                         June 30,
                                                      1999       1998
Cash Flows From Operating Activities:
Net earnings                                        $2,019     $1,762
Depreciation and amortization                          331        301
Provision for restructuring                              -        201
Gain on sale of businesses                               -      (201)
Other operating items                                 (65)         22
Receivables                                          (115)      (215)
Inventories                                          (229)       (84)
Accounts payable                                        16         79
Accrued expenses                                     (160)      (271)
Product liability                                    (432)      (381)
Insurance recoverable                                   19         25
Income taxes                                           348        187
Other assets and liabilities                         (146)       (67)

Net Cash Provided by Operating Activities            1,586      1,358

Cash Flows From Investing Activities:
Proceeds  from  sales  of  time  deposits   and         22        167
marketable securities
Purchases   of  time  deposits  and  marketable        (3)      (137)
securities
Additions to fixed assets                            (299)      (365)
Proceeds from sale of business                           -        406
Acquisition of businesses                                -       (67)
Other, net                                            (59)         16

Net  Cash  (Used  in) / Provided  by  Investing      (339)         20
Activities

Cash Flows From Financing Activities:
Short-term borrowings                                   87       (89)
Long-term debt                                        (34)         70
Issuances of common stock under stock plans            (2)         98
Purchases of treasury stock                          (633)    (1,126)
Dividends paid                                       (854)      (776)

Net Cash Used in Financing Activities              (1,436)    (1,823)

Effect of Exchange Rates on Cash                        26        (6)

Decrease in Cash and Cash Equivalents                (163)      (451)
Cash  and  Cash  Equivalents  at  Beginning  of      2,244      1,456
Period

Cash and Cash Equivalents at End of Period          $2,081     $1,005

<PAGE>


                       BRISTOL-MYERS SQUIBB COMPANY
              ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF
               FINANCIAL CONDITION AND RESULTS OF OPERATIONS
                                (UNAUDITED)


Basis of Presentation
- ---------------------

In   the  opinion  of  management,  the  accompanying  unaudited
consolidated   financial  statements  include  all   adjustments
(consisting  only of normal adjustments) necessary  for  a  fair
presentation  of the financial position of Bristol-Myers  Squibb
Company (the "Company") at June 30, 1999 and December 31,  1998,
the  results  of operations for the three and six  months  ended
June  30, 1999 and 1998, and cash flows for the six months ended
June 30, 1999 and 1998.  These consolidated financial statements
should  be  read in conjunction with the consolidated  financial
statements and the related notes included in the Company's  1998
Annual Report on Form 10-K.

Second Quarter Results of Operations
- ------------------------------------

Worldwide  sales  for the second quarter of 1999  increased  11%
over  the prior year to $4,920 million.  The consolidated  sales
growth resulted from a 10% increase due to volume, a 2% increase
due  to  changes  in  selling prices and a 1%  decrease  due  to
foreign  exchange rate fluctuations.  U.S. sales  increased  19%
and  international  sales  remained at  prior  year  levels  (an
increase of 3% excluding the effect of foreign exchange).

Sales  in  the medicines products segment, which is the  largest
segment  at 70% of total Company sales, increased 15%  over  the
second   quarter   of   1998  to  $3,435   million.    Worldwide
pharmaceutical  sales  increased 17%  with  U.S.  pharmaceutical
sales  up  29% over the prior year. Sales growth in  the  second
quarter resulted from a 14% increase in volume, a 2% increase in
selling  prices and a 1% decrease due to foreign  exchange  rate
fluctuations.

Sales of cardiovascular drugs, the largest product group in  the
segment,  increased 20% to $881 million (22%  excluding  foreign
exchange).   Sales of PRAVACHOL*, the Company's largest  selling
product,  increased  5% to $380 million.   Sales  of  the  anti-
hypertensive   MONOPRIL*,   a  second   generation   angiotensin
converting enzyme (ACE) inhibitor, increased 9% to $116 million.
PLAVIX,  a  platelet aggregation inhibitor for the reduction  of
stroke,  heart  attack  and  vascular death  in  atherosclerotic
patients  with recent stroke, recent heart attack or  peripheral
arterial  disease, had sales of $128 million  for  the  quarter.
AVAPRO, an angiotensin II receptor blocker for the treatment  of
hypertension,  had sales of $64 million. AVAPRO and  PLAVIX  are
cardiovascular  products that were launched  from  the  Bristol-
Myers  Squibb  and Sanofi S.A. joint venture. In May  1999,  the
Company  and Sanofi S.A. announced the availability in the  U.S.
of  the  anti-hypertensive AVALIDE, an angiotensin  II  receptor
blocker  combined  with a thiazide diuretic.  Sales  growth  for
these  cardiovascular products was partially offset  by  an  18%
decline  in CAPOTEN* sales due to the loss of patent exclusivity
in international markets.



*    Indicates  brand  names of products  which  are  registered
trademarks owned by the Company.

<PAGE>


Sales of anti-cancer drugs increased 19% to $852 million.  Sales
of  TAXOL*  (paclitaxel),  the  Company's  leading  anti-cancer
agent, increased 19% to $362 million as the product continues to
benefit from increased use in ovarian, breast and non-small cell
lung  cancer. In April 1999, the Company applied for  regulatory
approval  to  extend  the use of TAXOL* to treat  breast  cancer
patients following surgery.  In June 1999, the Company submitted
a  regulatory  application to the Food and  Drug  Administration
(FDA)  to  gain  marketing  approval  for  TAXOL*  injection  in
combination  with  Genentech, Inc's Herceptin  r  as  first-line
therapy for women with metastatic breast cancer.  Also in  June,
the  Company filed for European marketing authorization  to  the
Dutch  Health Authorities for the use of TAXOL* for the adjuvant
treatment of node-positive breast cancer.  Sales of PARAPLATIN*,
an anti-cancer agent used in combination with other chemotherapy
agents,  increased  11% to $138 million.   Sales  from  Oncology
Therapeutics  Network  (OTN), a specialty distributor  of  anti-
cancer  medicines and related products, increased  41%  to  $219
million.

Anti-infective drug sales of $584 million increased 2% over  the
prior  year.    ZERIT*  and  VIDEX*,  the  Company's  two  anti-
retroviral agents, increased 19% to $151 million and 41% to  $55
million,  respectively.  ZERIT* is  one  of  the  most  commonly
prescribed thymidine nucleoside reverse transcriptase  inhibitor
in  HIV therapy in most major markets in the world.  During  the
quarter,  the European Union gave a mutual recognition agreement
on  the  once-daily dosing of VIDEX* for the treatment  of  HIV.
International sales of MAXIPIME*, a fourth generation injectable
cephalosporin,  increased 19% to $32  million  in  the  quarter.
Effective  January  1,  1999,  Dura  Pharmaceuticals,  Inc.  was
appointed the exclusive distributor for MAXIPIME* in the  United
States.

The  Company is committing $100 million over the next five years
in  connection with the Secure the Future program,  whose  goals
are  to  speed  research, train doctors  and  enhance  community
outreach to fight HIV/AIDS in Southern Africa.

Central nervous system drug sales of $306 million increased  26%
with  sales of BUSPAR*, an anti-anxiety agent, and SERZONE*,  an
anti-depressant, increasing 57% to $132 million, and 18% to  $84
million, respectively.

GLUCOPHAGE,  the  leading  branded  oral  medication   for   the
treatment  of non-insulin dependent (type 2) diabetes, continued
its  strong  growth  rate  with sales  increasing  47%  to  $350
million.  In  May 1999, the FDA approved AVANDIA in  combination
with  GLUCOPHAGE for the treatment of type 2 diabetes.   AVANDIA
is  a product of SmithKline Beecham, and is being co-promoted by
Bristol-Myers Squibb Company in the United States.

Analgesic  sales decreased 2% to $168 million.  EXCEDRIN*  sales
increased  6%  to  $53  million and  sales  of  EFFERALGAN*,  an
effervescent analgesic sold primarily in France, decreased 6% to
$34 million.

Earnings  before  taxes  for  the  medicines  products   segment
increased  19%  to  $893 million in 1999.  As  a  percentage  of
sales, earnings before taxes for this segment improved to  26.0%
in  1999  from  25.2% in 1998.  Advertising and  promotion,  and
sales  force  expenses  improved,  as  a  percentage  of  sales,
partially  offset  by  increases in cost of  goods  sold,  as  a
percentage of sales.


<PAGE>


Sales  in  the  beauty care products segment  increased  4%  (5%
excluding  the  effect  of foreign exchange)  to  $626  million.
Sales  growth in the second quarter resulted from a 3%  increase
in volume, a 2% increase in selling prices and a 1% decrease due
to  foreign exchange rate fluctuations.  Clairol continues to be
the   number  one  hair  products  company  in  the  U.S.    The
introduction of a demand management manufacturing system  slowed
shipments  during the quarter. HERBAL ESSENCES*, the number  two
brand  in the U.S. shampoo/conditioner category and number three
in   the  body  wash  category,  continued  its  strong  growth,
increasing 16% to $159 million.  HERBAL ESSENCES FACIAL CARE*, a
line  of  skin  care products, was launched in March  1999,  and
contributed $6 million in second quarter sales. AUSSIE* products
contributed $33 million to second quarter sales, an increase  of
22%.  AUSSIE LAND*, hair products for children, was launched  in
March  1999 and contributed $7 million to second quarter  sales.
Sales  of DAILY DEFENSE* increased 100% to $30 million  for  the
second quarter, following its launch into international markets.
Earnings  before taxes for the beauty care segment decreased  to
$44  million in 1999 from $89 million in 1998, primarily due  to
the introduction of a demand management manufacturing system.

Sales  in the nutritional products segment increased 4% to  $438
million  (6%  excluding the effect of foreign  exchange).   U.S.
sales   increased  7%  and  international  sales  decreased   1%
primarily due to market conditions in Asia.  Sales growth in the
second  quarter  resulted from a 4% increase  in  volume,  a  2%
increase  in  selling prices and a 2% decrease  due  to  foreign
exchange   rate   fluctuations.  The  Company's   Mead   Johnson
subsidiary  continues  to  build  on  its  U.S.  and   worldwide
leadership position in the infant formula market.  ENFAMIL*, the
Company's largest-selling infant formula, recorded sales of $163
million,  a  5% increase over the prior year. BOOST*,  an  adult
nutritional  supplement,  also  contributed  to  sales   growth,
increasing  45%  to  $29 million. In March  1999,  Mead  Johnson
Nutritionals introduced VIACTIV* Soft Calcium Chews  to  address
the  need for a convenient, great-tasting calcium supplement for
women.   Sales  of  VIACTIV* reached $6 million  in  the  second
quarter.   Earnings  before taxes for  the  nutritional  segment
decreased  to $71 million in 1999 from $74 million in 1998,  and
as  a percentage of sales, decreased to 16.2% in 1999 from 17.5%
in 1998 primarily due to market conditions in Asia.

Medical  device  segment sales increased  4%  to  $421  million,
excluding  sales  from a 1998 distribution  agreement  with  the
acquirer  of Zimmer's divested arthroscopy and powered  surgical
instrument  business.   On  this  basis,  medical  device  sales
increased  5% due to volume and decreased 1% due to  changes  in
selling  prices. Fluctuations in foreign exchange had no  effect
on  medical  devices  sales.  Zimmer sales on  this  same  basis
increased  7%  to $240 million (6% excluding foreign  exchange).
Knee  joint  replacement sales increased 12% to $95 million  and
hip  replacement  sales increased 9% to $72  million.   ConvaTec
sales  increased  1%  to  $180  million  (2%  excluding  foreign
exchange).   Sales  of  ostomy products  increased  2%  to  $116
million partially offset by a decrease in wound care products of
3% to $56 million.  Earnings before taxes for the medical device
segment increased 12% to $91 million in 1999 from $81 million in
1998  and, as a percentage of sales, increased to 21.6% in  1999
from  19.4%  in  1998,  primarily due to improved  manufacturing
efficiencies.


<PAGE>


Operating Expenses
- ------------------

Total  expenses  for  the quarter ended  June  30,  1999,  as  a
percentage  of  sales, decreased to 73.2% from 73.7% in 1998. Cost
of products sold, as a percentage of sales, increased to 27.7% from
27.2%  in  1998  due  to  revenue growth of  OTN  which  carries
significantly  lower margins.  Expenditures for advertising  and
promotion  in support of new and existing products increased  4%
to   $666   million  from  $642  million.   Marketing,  selling,
administrative  and  other  expenses  increased  9%  to   $1,122
million. Research and development expenditures increased 18%  to
$453 million from $384 million in 1998.  Pharmaceutical research
and  development spending increased 19% over the prior year, and
as a percentage of pharmaceutical sales, was 12.7% in the second
quarter  of  1999 and 12.6% in the second quarter  of  1998.  In
research  and development highlights this quarter, data  on  the
Company's  new  novel cardiovascular agent in Phase  II  trials,
VANLEV*  (omapatrilat), were presented at the American  Society
of  Hypertension.   The  Phase II results  showed  that  use  of
VANLEV* was effective in reducing both systolic (top number) and
diastolic (bottom number) blood pressure.  The Company plans  to
file for regulatory approval for VANLEV* with the FDA by the end
of  the  year  with worldwide regulatory filings to follow.  The
Company  is  also awaiting marketing approval from the  FDA  for
ORZEL*  (UFT),  an  oral  therapy for  colorectal  cancer,  and
TEQUIN*  (gatifloxacin), a broad-spectrum quinolone  antibiotic
for the treatment of multiple common infections, including those
of the respiratory tract.

Earnings
- --------

Earnings  before  income taxes for the second quarter  increased
13% to $1,318 million from $1,164 million in 1998. The effective
tax  rate on earnings before income taxes decreased to 27.8%  in
1999  from 28.3% in 1998. The decrease in the effective tax rate
is  due to increased earnings from lower tax rate jurisdictions.
Net  earnings  increased 14% to $952 million from $835  million
in 1998. Basic earnings per share increased 14% to $.48 from $.42
in 1998 and  diluted earnings per share increased 15% to $.47 from
$.41 in 1998.

Six Months Results of Operations
- --------------------------------

Worldwide  sales for the first six months of 1999 increased  10%
(11%  excluding the effect of foreign exchange) over  the  prior
year to $9,774 million.   The consolidated sales growth resulted
from  a  9% increase due to volume, a 2% increase due to changes
in selling prices and a 1% decrease due to the effect of foreign
exchange.   U.S.  sales  increased 16% and  international  sales
increased 2% (3% excluding the effect of foreign exchange).

Sales  in the medicines products segment increased 14% over  the
prior  year  to  $6,865 million. Worldwide pharmaceutical  sales
increased  16% with U.S. pharmaceutical sales up  25%  over  the
prior year. Sales growth for the six months resulted from a  12%
increase  in  volume,  a 2% increase in selling  prices  and  no
effect from foreign exchange rate fluctuations.


<PAGE>


Cardiovascular drug sales of $1,802 million increased  17%  from
the  prior  year.  PRAVACHOL* increased 7% to $866  million  and
MONOPRIL*  increased 10% to $222 million.  PLAVIX had  sales  of
$216  million  for the six months and AVAPRO had sales  of  $114
million.   Sales growth for these products was partially  offset
by  a  22% decline in CAPOTEN* sales, due to the loss of  patent
exclusivity  in  international markets.   Sales  of  anti-cancer
drugs  increased  24% to $1,687 million due to strong  sales  of
TAXOL*  and PARAPLATIN* which increased 24% to $692 million  and
13% to $287 million, respectively.  Sales from OTN increased 42%
to  $420  million.  Anti-infective drug sales  increased  5%  to
$1,217  million as ZERIT* and VIDEX* recorded gains  of  18%  to
$302   million   and   34%   to   $99   million,   respectively.
International  sales of MAXIPIME* increased 24% to  $62  million
for  the  six months and sales of CEFZIL* increased 12% to  $220
million.  Sales of central nervous system drugs increased 10% to
$574  million  as  BUSPAR* and SERZONE* increased  15%  to  $264
million   and  9%  to  $147  million,  respectively.  GLUCOPHAGE
continued  its strong growth and increased 51% to $631  million.
Analgesic  sales of $360 million increased 3% primarily  due  to
increases in EFFERALGAN* of 11% to $84 million and DAFALGAN*  of
16% to $36 million partially offset by decreases in EXCEDRIN* of
3% to $112 million, coming off significant increases in 1998 due
to the launch of EXCEDRIN MIGRAINE*.

Earnings  before  taxes  for  the  medicines  products   segment
increased  15%  to $1,894 million in 1999.  As a  percentage  of
sales, earnings before taxes for this segment improved to  27.6%
in 1999 from 27.2% in 1998.

Sales  in  the  beauty care products segment  increased  5%  (6%
excluding  the  effect of foreign exchange) to  $1,198  million.
Sales  growth  resulted  from a 4%  increase  in  volume,  a  2%
increase  in  selling prices and a 1% decrease  due  to  foreign
exchange  rate  fluctuations.  HERBAL  ESSENCES*  continued  its
strong  growth, increasing 21% to $323 million.  HERBAL ESSENCES
FACIAL CARE* contributed $12 million in six month sales. AUSSIE*
products contributed $61 million, an increase of 22%, and  sales
of  DAILY  DEFENSE* increased 100% to $64 million  for  the  six
months.   Earnings  before  taxes for the  beauty  care  segment
decreased  to  $109 million in 1999 from $161 million  in  1998,
primarily  due  to  the  introduction  of  a  demand  management
manufacturing system.

Sales  in the nutritional products segment increased 2% to  $888
million  (3%  excluding the effect of foreign exchange).   Sales
growth for the six months resulted from a 2% increase in volume,
a 1% increase in selling prices and a 1% decrease due to foreign
exchange rate fluctuations. Total infant formula sales increased
2% to $605 million.  ENFAMIL* recorded sales of $350 million,  a
6%  increase  over the prior year. BOOST*, an adult  nutritional
supplement,  increased 30% to $52 million.  Six month  sales  of
VIACTIV*  were  $9  million.   Earnings  before  taxes  for  the
nutritional segment were $172 million in 1999 compared  to  $169
million  in  1998 and, as a percentage of sales, were  19.4%  in
both 1999 and 1998.

Medical  device  segment sales increased  4%  to  $823  million,
excluding  sales  from a 1998 distribution  agreement  with  the
acquirer  of Zimmer's divested arthroscopy and powered  surgical
instrument  business.   On  this  basis,  medical  device  sales
increased  3% due to volume and 1% due to foreign exchange  with
no  effect  from price changes. Zimmer sales on the  same  basis
increased  7%  to  $478 million.  Knee joint  replacement  sales
increased  10%  to  $189  million  and  hip  replacement   sales
increased  8% to $143 million. ConvaTec remained at  prior  year
levels of $344 million as sales of ostomy products increased  2%
to  $224  million and wound care products decreased 2%  to  $111
million.   Earnings before taxes for the medical devices segment
increased 10% to $163 million in 1999 from $148 million in  1998
and,  as  a percentage of sales, improved to 19.8% in 1999  from
17.9%  in  1998, resulting from a decrease, as a  percentage  of
sales, in cost of products sold.


<PAGE>


Operating Expenses
- ------------------

Total  expenses  for the six months ended June 30,  1999,  as  a
percentage  of  sales, decreased to 71.4% from 72.3% in 1998. Cost
of products  sold  increased to 27.3% of sales from 26.6%  in  1998
primarily  due  to  revenue  growth of  OTN.   Expenditures  for
advertising  and  promotion  in  support  of  new  and  existing
products  decreased 1% to $1,195 million from $1,213 million  in
1998.  Marketing,  selling, administrative  and  other  expenses
increased  8%  to  $2,243 million from $2,082 million  in  1998.
Research  and  development expenditures increased  14%  to  $876
million  from $767 million in 1998. Pharmaceutical research  and
development spending increased 15% over the prior year, and as a
percentage of pharmaceutical sales, was 12.4% compared to  12.6%
in the same period of 1998.

Earnings
- --------

Earnings before income taxes for the six months increased 14% to
$2,794  million from $2,456 million in 1998. The  effective  tax
rate  on earnings before income taxes decreased to 27.8% in 1999
from 28.3% in 1998. Net earnings increased 15% to $2,019 million
from  $1,762 million in 1998. Basic earnings per share increased
15% to $1.02 from $.89 in 1998 and diluted earnings per share
increased 15% to $1.00 from $.87 in 1998.

Financial Position
- ------------------

The  balance  sheet at June 30, 1999 and the statement  of  cash
flows for the six months then ended reflect the Company's strong
financial  position.  The Company continues to maintain  a  high
level of working capital, increasing to $3.3 billion at June 30,
1999, from $3.0 billion at December 31, 1998.

Long-Term Debt decreased slightly to $1,327 million from  $1,364
million at December 1998.

Internally generated funds continue to be the Company's  primary
source  for  financing expenditures for new plant and equipment.
Net  cash  provided  by Operating Activities  increased  17%  to
$1,586  million in 1999.  Additions to fixed assets for the  six
months  ended June 30, 1999 were $299 million compared  to  $365
million during the same period of 1998.

During the six months ended June 30, 1999, the Company purchased
10.2  million shares of its common stock at a total cost of $633
million.

During  the first quarter of 1998, the Company divested its  BAN
brand  of  anti-perspirants  and deodorants  for  $165  million,
resulting  in a gain of $125 million before taxes.   During  the
second  quarter,  the Company divested A/S GEA, a  Denmark-based
generic   drug   business,  and  Hexachimie,  a  fine   chemical
manufacturer  based in France, resulting in a combined  gain  of
$76  million before taxes.  The Company recorded provisions  for
restructuring of $125 million before taxes in the first  quarter
and  $76  million  before  taxes  in  the  second  quarter.  The
restructuring charges primarily related to the consolidation and
closure  of  plants and facilities as part of the Company's  on-
going productivity programs.



<PAGE>




Business Segments
- -----------------



                                 Three Months Ended June 30,

                              Net Sales          Earnings Before
                                                       Taxes
(in millions)              1999        1998       1999       1998

Medicines Products       $3,435      $2,987       $893       $753
Beauty Care Products        626         603         44         89
Nutritional Products        438         423         71         74
Medical Devices             421         417         91         81
Other                         -           -        219        167
Total Company            $4,920      $4,430     $1,318     $1,164




                                  Six Months Ended June 30,

                              Net Sales          Earnings Before
                                                       Taxes
(in millions)              1999        1998       1999       1998

Medicines Products       $6,865      $6,044     $1,894     $1,646
Beauty Care Products      1,198       1,137        109        161
Nutritional Products        888         870        172        169
Medical Devices             823         825        163        148
Other                         -           -        456        332
Total Company            $9,774      $8,876     $2,794     $2,456



Included  in earnings before taxes of each segment is a  cost  of
capital  charge.   The offset to the cost of  capital  charge  is
included  in  Other. In addition, Other principally  consists  of
interest   income,   interest  expense,  certain   administrative
expenses  and  allocations to the industry segments  for  certain
corporate  programs. In the second quarter of  1998,  Other  also
includes  the  gain on sale of a business of $76  million  and  a
provision  for restructuring of $76 million.  For the  first  six
months  of  1998,  Other  also  includes  the  gain  on  sale  of
businesses  of $201 million and a provision for restructuring  of
$201  million.   In  addition, the segment  information  reflects
certain internal organizational changes made in 1999. Prior  year
data have been restated accordingly.



<PAGE>




PART II - OTHER INFORMATION
- ---------------------------


Item 6.  Exhibits and Reports on Form 8-K
- -----------------------------------------

a) Exhibits (listed by number corresponding to the Exhibit Table
    of Item 601 in Regulation S-K).


   Exhibit Number and Description                         Page
   -------------------------------                        -----

   27.  Bristol-Myers Squibb Company Financial Data ScheduleE-27-1


b) Reports on Form 8-K.

The  Registrant did not file any reports on Form 8-K during  the
   quarter ended June 30, 1999.



<PAGE>


                                SIGNATURES
                                ----------



Pursuant  to  the  requirements of the Securities Exchange  Act  of
1934,  the  Registrant has duly caused this report to be signed  on
its behalf by the undersigned, thereunto duly authorized.






                                 BRISTOL-MYERS SQUIBB COMPANY
                                         (Registrant)







Date: August 13, 1999              /s/ Harrison M. Bains, Jr.

                                       Harrison M. Bains, Jr.
                                   Vice President and Treasurer







Date: August 13, 1999              /s/ Frederick S. Schiff

                                       Frederick S. Schiff
                                 Vice President Financial Operations
                                          and Controller


<PAGE>


<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
Exhibit 27 for Bristol-Myers Squibb Company for the period ended 6/30/99
<MULTIPLIER> 1000000

<S>                                                <C>
<PERIOD-TYPE>                                    6-MOS
<FISCAL-YEAR-END>                          DEC-31-1999 <F1>
<PERIOD-END>                               JUN-30-1999
<CASH>                                            2081
<SECURITIES>                                       267
<RECEIVABLES>                                     3218 <F2>
<ALLOWANCES>                                         0
<INVENTORY>                                       2044
<CURRENT-ASSETS>                                  8658
<PP&E>                                            7613
<DEPRECIATION>                                    3158
<TOTAL-ASSETS>                                   16214
<CURRENT-LIABILITIES>                             5367
<BONDS>                                           1327
                                0
                                          0
<COMMON>                                           219
<OTHER-SE>                                        7841
<TOTAL-LIABILITY-AND-EQUITY>                     16214
<SALES>                                           9774
<TOTAL-REVENUES>                                  9774
<CGS>                                             2666
<TOTAL-COSTS>                                     2666
<OTHER-EXPENSES>                                  2071
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                  64
<INCOME-PRETAX>                                   2794
<INCOME-TAX>                                       775
<INCOME-CONTINUING>                               2019
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                      2019
<EPS-BASIC>                                     1.02
<EPS-DILUTED>                                     1.00
<FN>
<F1>
Items reported as "zero" are not applicable or are immaterial to the
consolidated financial position of the Company.
<F2>
Receivables are reported net of allowances for doubtful accounts.



</TABLE>


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