BRISTOL MYERS SQUIBB CO
10-K, 2000-03-30
PHARMACEUTICAL PREPARATIONS
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                    SECURITIES AND EXCHANGE COMMISSION
                          WASHINGTON, D.C.  20549

                                 FORM 10-K

         [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                      SECURITIES EXCHANGE ACT OF 1934

                For the fiscal year ended December 31, 1999

                       Commission File Number 1-1136

                       BRISTOL-MYERS SQUIBB COMPANY
          (Exact name of registrant as specified in its charter)


                 Delaware                                22-079-0350
       (State or other jurisdiction of        (IRS Employer Identification No.)
        incorporation or organization)

                  345 Park Avenue, New York, N.Y.  10154
                 (Address of principal executive offices)
                         Telephone: (212) 546-4000


Securities registered pursuant to Section 12(b) of the Act:


                                                     Name of each exchange on
     Title of each class                                 which registered


     Common Stock,$.10 Par Value                     New York Stock Exchange
                                                     Pacific Exchange, Inc.


     $2 Convertible Preferred Stock, $1 Par Value    New York Stock Exchange
                                                     Pacific Exchange, Inc.


Securities registered pursuant to Section 12(g) of the Act: None

Indicate by check mark if disclosure of delinquent filers pursuant to  Item
405  of  Regulation S-K is not contained herein, and will not be contained,
to  the  best  of  the  registrant's  knowledge,  in  definitive  proxy  or
information statements incorporated by reference in Part III of  this  Form
10-K or any amendment to this Form 10-K. [X]

Indicate  by  check mark whether the registrant (1) has filed  all  reports
required to be filed by Section 13 or 15(d) of the Securities Exchange  Act
of 1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject  to
such filing requirements for the past 90 days.  Yes [X]   No [   ]

The  aggregate market value of voting stock held by non-affiliates  of  the
registrant  as of February 29, 2000 was $112,954,123,592. At  February  29,
2000, there were 1,975,859,149 shares of common stock outstanding.

                    Documents incorporated by reference

Proxy Statement for Annual Meeting of Stockholders on May 2, 2000.Part III

<PAGE>

                                   PART I
                                 ---------
Item 1.        BUSINESS.

DESCRIPTION OF BRISTOL-MYERS SQUIBB COMPANY
- -------------------------------------------

General:
- ---------

Bristol-Myers Squibb Company ("Bristol-Myers Squibb" or the "Company")  was
incorporated under the laws of the State of Delaware in August  1933  under
the  name Bristol-Myers Company as successor to a New York business started
in  1887.  In 1989, the Bristol-Myers Company changed its name to  Bristol-
Myers  Squibb  Company, as a result of a merger. The Company,  through  its
divisions  and  subsidiaries,  is  a  major  producer  and  distributor  of
pharmaceuticals,  consumer  medicines, nutritionals,  medical  devices  and
beauty care products. In general, the business of the Company's segments is
not seasonal.

BUSINESS SEGMENTS
- -----------------

Reference  is  made  to Note 2 Acquisitions and Divestitures  and  Note  12
Segment  Information  in  the  Notes to Consolidated  Financial  Statements
included in Part II, Item 8 of this Form 10-K Annual Report.

DESCRIPTION OF SEGMENTS
- -----------------------

MEDICINES:
- ----------

This segment includes sales of pharmaceuticals and consumer medicines.
Sales of selected products and product categories are as follows:

                                          1999      1998     1997
                                        ------    ------   ------
 PRAVACHOL*                             $1,704    $1,643   $1.437
 TAXOL*                                  1,481     1,206      941
 GLUCOPHAGE                              1,317       862      579
 Oncology Therapeutics Network             894       657      480
 BUSPAR*                                   605       531      443
 ZERIT*                                    605       551      398
 PARAPLATIN*                               600       525      437
 PLAVIX                                    547       144        -
 CAPOTEN*/CAPOZIDE*                        484       636      795
 MONOPRIL*                                 424       380      328
 CEFZIL*                                   402       358      318
 SERZONE*                                  332       257      185
 AVAPRO                                    255       123       28
 EXCEDRIN*                                 240       241      206
 VIDEX*                                    205       162      152

                                        1
<PAGE>

PRAVACHOL*            pravastatin  sodium, an HMG Co-A reductase  inhibitor
                      indicated  for  primary  hypercholestermia.   Patents
                      expire   in   the  U.S.  in  October  2005   and   in
                      international markets from 2000 through 2010.

TAXOL*                paclitaxel,  used  in  the  treatment  of  refractory
                      ovarian   cancer,  first-line  treatment  of  ovarian
                      cancer  in  combination  with cisplatin,  second-line
                      treatment of AIDS-related Kaposi's Sarcoma, treatment
                      of   metastatic  breast  cancer  after   failure   of
                      combination chemotherapy, adjuvant treatment of  node
                      positive breast cancer and in the treatment  of  non-
                      small  cell  lung carcinoma with cisplatin.   Certain
                      patent  claims  related to the three-hour  method  of
                      administration patents expire in 2012 in the U.S. and
                      2013 outside the U.S.  Reference is also made to Item
                      3  Legal  Proceedings in Part 1  of  this  Form  10-K
                      Annual  Report and to Note 15 Litigation in  Part  2,
                      Item  8,  of  this Form 10-K Annual  Report.   Hatch-
                      Waxman  exclusivity  for  first-line  ovarian  cancer
                      expires April 2001, for non-small cell lung cancer in
                      January  2002  and  for  adjuvant  breast  cancer  in
                      October 2002.

GLUCOPHAGE            metformin, an oral anti-diabetes agent for type 2 non-
                      insulin-dependent diabetes. Hatch-Waxman  exclusivity
                      expires in September 2000.

Oncology Therapeutics
Network               a  specialty distributor of anti-cancer medicines and
                      related products.

BUSPAR*               buspirone,  a novel anti-anxiety agent for persistent
                      anxiety   with  or  without  accompanying  depressive
                      symptoms. U.S. anxiolytic use patent expires  in  May
                      2000. Other international patents expired in 1999.

ZERIT*                stavudine,  used  in the treatment  of  persons  with
                      advanced HIV disease. Patent expires in the  U.S.  in
                      June 2008 and internationally from 2007 through 2008.

PARAPLATIN*           carboplatin,  a chemotherapeutic agent  used  in  the
                      treatment  of ovarian cancer. Patent expires  in  the
                      U.S. in April 2004 and in France in June 2000.

PLAVIX                clopidogrel,  a platelet inhibitor, co-developed  and
                      jointly marketed with Sanofi S.A.

CAPOTEN*/CAPOZIDE*    captopril,  an  angiotensin converting  enzyme  (ACE)
                      inhibitor.  Patents have expired in the U.S.  and  in
                      all significant international markets.

MONOPRIL*             fosinopril sodium, a second-generation ACE  inhibitor
                      with once-a-day dosing indicated for the treatment of
                      hypertension.  U.S. patent expires in  December  2002
                      and in international markets from 2001 through 2008.

CEFZIL*               cefprozil,   an  oral  cephalosporin  used   in   the
                      treatment  of  respiratory infections and  sinusitis.
                      U.S.   patent  expires  in  December  2005   and   in
                      international
                      markets from 2003 through 2009.


*     Indicates  brand  names of products which are  registered  trademarks
owned by the Company.

                                        2

<PAGE>

SERZONE*              nefazodone,   an  antidepressant  treatment.   Patent
                      expires in the U.S. in March 2003 and internationally
                      from 2002 through 2010.

AVAPRO                irbesartan,  an  angiotensin II  receptor  antagonist
                      indicated  for  the  treatment of  hypertension,  co-
                      developed and jointly marketed with Sanofi S.A.

EXCEDRIN*             an   analgesic   with  acetaminophen  and   caffeine.
                      EXCEDRIN* Migraine is indicated for the treatment  of
                      the full migraine syndrome.

VIDEX*                didanosine,  an  antiretroviral  drug  used  in   the
                      treatment  of  adult  and  pediatric  patients   with
                      advanced    human   immunodeficiency   virus    (HIV)
                      infection. Patent expires in the U.S. in August  2006
                      and internationally from 2006 through 2009.


BEAUTY CARE:
- ------------

This segment includes sales of haircoloring and hair care preparations and
other beauty care products.

                                          1999      1998     1997
                                        ------    ------   ------
Hair care                               $1,250    $1,179     $794
Haircolor                                  905       894      841

The principal products in this segment are:

NICE 'N EASY*         haircolorings
MISS CLAIROL*
HYDRIENCE*
NATURAL INSTINCTS*
ULTRESS*
LOVING CARE*
REVITALIQUE*

HERBAL ESSENCES*      complete lines of shampoos and conditioners
AUSSIE*
INFUSIUM 23*
DAILY DEFENSE*

SYSTEME BIOLAGE*      professional hair care products sold
MATRIX ESSENTIALS*    exclusively in beauty salons
VITAL NUTRIENTS*
VAVOOM*

MUM*                  anti-perspirants and deodorants
SEA BREEZE*           skin care products

                                        3
<PAGE>

NUTRITIONALS:
- -------------

This segment includes sales of infant formulas and other nutritional
products.

                                          1999      1998     1997
                                        ------    ------   ------
Infant formulas                         $1,233    $1,203   $1,219

The principal products in this segment are:

ENFAMIL*/ENFALAC*     infant formula products
PROSOBEE*
NUTRAMIGEN*
LACTOFREE*

ENFAPRO*              follow-up formula products for older babies
NEXT STEP*
ALACTA NF*
ENFAGROW*

SUSTAGEN*             nutritional supplements and specialties
CHOCO MILK*
ISOCAL*
SUSTACAL*
NUTRAMENT*
BOOST*
VIACTIV*

PLUSSSZ*              vitamins
POLY-VI-SOL*
POLY-VI-FLOR*
NATALINS*


MEDICAL DEVICES:
- ----------------

This  segment includes sales of orthopaedic implants, ostomy and wound care
products and other medical devices.
                                          1999      1998     1997
                                        ------    ------   ------
Orthopaedic implants                      $665      $596     $615
Ostomy                                     449       464      451

The principal products in this segment are:

NEXGEN*               Complete Knee Solution

                                        4
<PAGE>

VERSYS*               Hip System

CENTRALIGN*           Precoat Hip Prosthesis orthopaedic implants

ACTIVE LIFE/          ostomy care products
COLODRESS*
SUR-FIT/
COMBIHESIVE/SECURE*

DUODERM*              wound care products


SOURCES AND AVAILABILITY OF RAW MATERIALS
- -----------------------------------------

In  general, Bristol-Myers Squibb purchases the principal raw materials and
supplies  used  in each industry segment in the open market.  Substantially
all such materials are obtainable from a number of sources so that the loss
of any one source of supply would not have a material adverse effect on the
Company.


PATENTS, TRADEMARKS AND LICENSES
- --------------------------------

The  Company  owns or is licensed under a number of patents in  the  United
States  and  foreign  countries  covering  products,  principally  in   the
medicines  and medical devices segments, and has also developed many  brand
names  and  trademarks for products in each industry segment.  The  Company
considers  the  overall  protection of its patent,  trademark  and  license
rights  to  be  of  material value and acts to protect  these  rights  from
infringement. In the years 2000 and 2001 exclusivity periods are  scheduled
to  expire  or  have  expired for GLUCOPHAGE, BUSPAR*  and  certain  TAXOL*
claims.  The  Company  believes that no single  patent  or  license  is  of
material importance in relation to the business as a whole.


COMPETITION, DISTRIBUTION AND CUSTOMERS
- ---------------------------------------

The  markets  in  which Bristol-Myers Squibb competes are generally  broad-
based  and highly competitive. The principal means of competition  utilized
to  market  the products of Bristol-Myers Squibb include quality,  service,
price and product performance. The pharmaceutical products of the Medicines
segment and the products of the Medical Devices segment are promoted  on  a
national  and international basis in medical journals and directly  to  the
medical  profession.  The  Company  is  also  utilizing  direct-to-consumer
advertising for a number of its pharmaceutical products. Most of the  other
products of Bristol-Myers Squibb are generally advertised and promoted on a
national  and  international basis through the use  of  television,  radio,
print  media,  consumer offers, and window and in-store displays.  Bristol-
Myers  Squibb's products are principally sold to the wholesale  and  retail
trade  both  nationally  and  internationally.  Certain  products  of   the
Medicines  and  Medical  Devices segments  are  also  sold  to  other  drug
manufacturers, hospitals and the medical profession. None of  the  segments
is dependent upon a single customer, or a few customers, such that the loss
of any one or more would have a material adverse effect on the segment.

                                        5
<PAGE>

RESEARCH AND DEVELOPMENT
- ------------------------

Research and development is essential to Bristol-Myers Squibb's businesses,
particularly   to  the  Medicines  Segment.  Pharmaceutical  research   and
development  is  carried  out  by the Bristol-Myers  Squibb  Pharmaceutical
Research  Institute which has major facilities in Princeton,  Hopewell  and
New  Brunswick,  New  Jersey; and Wallingford, Connecticut.  Pharmaceutical
research and development is also carried out at various other facilities in
the  United  States and in Belgium, Canada, France, Italy, Japan,  and  the
United  Kingdom.  Management continues to emphasize leadership,  innovation
and productivity as strategies for success in the Research Institute.

Bristol-Myers Squibb spent $1,843 million in 1999, $1,577 million  in  1998
and  $1,385  million in 1997 on Company sponsored research and  development
activities.  Pharmaceutical  research  and  development  spending,   as   a
percentage of pharmaceutical sales, was 12.6% in 1999 compared to 12.4%  in
1998 and 12.0% in 1997.


REGULATION
- ----------

Most  aspects  of  the Company's business are subject  to  some  degree  of
government  regulation  in  the  countries  in  which  its  operations  are
conducted.  The  Company's policy is to comply fully  with  all  regulatory
requirements  applying to its products and operations. For  some  products,
and  in  some  countries,  government regulation  is  significant  and,  in
general, there is a trend to more stringent regulation. The Company devotes
significant  time, effort and expense addressing the extensive governmental
regulatory   requirements   applicable  to  its   business.    Governmental
regulatory  actions  can  result  in the recall  or  seizure  of  products,
suspension  or revocation of the authority necessary for the production  or
sale of a product, and other civil and criminal sanctions.

In  the  United  States,  the drug, medical device,  diagnostic,  food  and
cosmetic industries in which the Company operates have long been subject to
regulation  by various federal, state and local agencies, primarily  as  to
product manufacture, safety, efficacy, advertising and labeling.

In  addition,  governmental bodies in the United States as  well  as  other
countries  have expressed concern about costs relating to health care  and,
in  some  cases,  have focused attention on the pricing  of  drugs  and  on
appropriate drug utilization. Government regulation in these areas  already
exists  in  some countries and may be expanded significantly in the  United
States and other countries in the future.

While the Company is unable to predict the extent to which its business may
be  affected  by  future  regulatory developments,  it  believes  that  its
substantial  experience  dealing with governmental regulatory  requirements
and restrictions on its operations throughout the world and its development
of new and improved products should enable it to compete effectively within
this environment.


EMPLOYEES
- ---------

Bristol-Myers Squibb employed approximately 54,500 people at  December  31,
1999.

                                        6
<PAGE>

DOMESTIC AND FOREIGN OPERATIONS
- -------------------------------

Reference  is  made to Note 10 Financial Instruments, and Note  12  Segment
Information  in the Notes to Consolidated Financial Statements included  in
Part II, Item 8 of this Form 10-K Annual Report.

International operations are subject to certain risks which are inherent in
conducting   business   abroad,  including  possible   nationalization   or
expropriation,  price  and  exchange  controls,  limitations   on   foreign
participation  in  local  enterprises and  other  restrictive  governmental
actions.  In  addition, changes in the relative value  of  currencies  take
place  from  time to time and their effects may be favorable or unfavorable
on  Bristol-Myers  Squibb's  operations. There  are  currency  restrictions
relating to repatriation of earnings in certain countries.


Item 2.        PROPERTIES.

Bristol-Myers  Squibb's world headquarters is located at 345  Park  Avenue,
New  York, New York, where it leases approximately 460,500 square  feet  of
floor  space,  approximately 206,300 square feet  of  which  is  sublet  to
others.  The  headquarters  for  the Company's  segments  are  as  follows:
Medicines  world headquarters is located in Princeton, New  Jersey;  Beauty
Care  in  Stamford, Connecticut; Nutritionals in Evansville,  Indiana;  and
Medical Devices in Warsaw, Indiana and Skillman, New Jersey.

Bristol-Myers  Squibb  manufactures products at forty-two  major  worldwide
locations with an aggregate floor space of approximately 13,300,000  square
feet. All facilities are owned by Bristol-Myers Squibb. The following table
illustrates   the  segment  and  geographic  location  of   the   Company's
significant manufacturing facilities.


                                    Beauty                   Medical
                          Medicines  Care     Nutritionals   Devices   Total
                          --------------------------------------------------
United States                  8        2            2           4       16
Europe, Mid East and Africa    7        1            1           1       10
Other Western Hemisphere       6        3            2           -       11
Pacific                        4        -            1           -        5
                            ----     ----         ----        ----     ----
Total                         25        6            6           5       42
                            ----     ----         ----        ----     ----


Portions  of  these  facilities and other facilities  owned  or  leased  by
Bristol-Myers  Squibb  in  the United States and  elsewhere  are  used  for
research, administration, storage and distribution. Bristol-Myers  Squibb's
facilities  are  well-maintained, adequately insured  and  in  satisfactory
condition.

                                        7
<PAGE>



Item 3.          LEGAL PROCEEDINGS.

Various  lawsuits, claims and proceedings of a nature considered normal  to
its  businesses  are  pending  against  the  Company  and  certain  of  its
subsidiaries. The most significant of these are described below.

Reference  is  made to Note 15 Litigation in the Notes to the  Consolidated
Financial Statements included in Part II, Item 8 of this Report.

Breast Implant Litigation
- -------------------------

The  Company, together with its subsidiary, Medical Engineering Corporation
(MEC),  and  certain other companies, has been named as a  defendant  in  a
number  of  claims and lawsuits alleging damages for personal  injuries  of
various  types  resulting  from polyurethane-covered  breast  implants  and
smooth-walled  breast implants formerly manufactured by MEC  or  a  related
Company.  Of  the more than 90,000 claims or potential claims  against  the
Company in direct lawsuits or through registration in the nationwide  class
action  settlement  approved by the Federal District Court  in  Birmingham,
Alabama  (the "Revised Settlement"), most have been dealt with through  the
Revised  Settlement, other settlements, or trial. As of December 31,  1999,
the  Company's contingent liability in respect of breast implant claims was
limited  to  residual unpaid Revised Settlement obligations and to  roughly
1,700  remaining  opt-outs who have pursued or may pursue their  claims  in
court.

As  of December 31, 1999, approximately 6,700 United States and 200 foreign
breast  implant recipients were plaintiffs in lawsuits pending  in  federal
and  state  courts in the United States and certain courts  in  Canada  and
Australia. These figures include the claims of plaintiffs that are  in  the
process  of being settled and/or dismissed. In these lawsuits, about  3,660
U.S.  and  49  foreign plaintiffs opted out of the Revised Settlement.  The
lawsuits  of the 3,040 U.S. plaintiffs who did not opt out are expected  to
be  dismissed  since these plaintiffs are among the estimated 74,000  women
with MEC implants who chose to participate in the nationwide settlement. Of
the  3,660  opt-out plaintiffs, an estimated 1,960 have claims  based  upon
products that were not manufactured or sold by MEC or that have been or are
in  the  process of being settled and/or dismissed. Accordingly, the number
of  remaining  plaintiffs who have pursued or may pursue  their  claims  in
court  against  the Company is roughly 1,700, as stated  in  the  preceding
paragraph.

Under the terms of the Revised Settlement, additional opt-outs are expected
to  be  minimal since the deadline for U.S. class members to  opt  out  has
passed.  In addition, the Company's remaining obligations under the Revised
Settlement Program are limited because most payments to "Current Claimants"
have already been made, no additional "Current Claims" may be filed without
court  approval,  and  because  payments  of  claims  to  so-called  "Other
Registrants" and "Late Registrants" are limited by the terms of the Revised
Settlement.  Separate class action settlements have been  approved  in  the
provincial courts of Ontario and Quebec, and an agreement has been  reached
under  which  other  foreign  breast implant recipients  may  settle  their
claims.  The Company believes it will be able to address remaining  opt-out
claims  as  well  as  expected  remaining  obligations  under  the  Revised
Settlement Program within its reserves described below.

Breast  implants  were  manufactured by several companies,  including  MEC,
which  the Company acquired in 1982. Until 1991, MEC manufactured two types
of  breast  implants,  polyurethane-covered silicone  breast  implants  and
smooth-walled  silicone  breast  implants. In  these  lawsuits,  plaintiffs
typically contend that silicone in breast implants causes systemic  disease
and/or  local  complications.  Some  plaintiffs  with  polyurethane-covered
silicone  breast  implants contend that the polyurethane  component  causes
injury,  including cancer.  Most of the disease claims involve non-specific
complaints such as chronic fatigue, aches and pains and other symptoms that

                                        8
<PAGE>

commonly   affect  the  population  at  large.   Many  women  claim   local
complications  such as rupture, hardening or contracture, and disfigurement
or scarring. The plaintiffs typically seek compensatory damages for alleged
medical conditions and emotional distress as well as punitive damages.  The
defendants  have  based  their defense in part  on  the  lack  of  credible
scientific  evidence that breast implants cause disease. Many  large  scale
epidemiological  studies have found no connection between  breast  implants
and  the alleged diseases. Defendants also contend that warnings set  forth
in the product literature adequately advised physicians and surgeons of the
risks of local complications.

The  Company  is  a  participant  in  the  national  class  action  Revised
Settlement Program approved on December 22, 1995, by the Honorable  Sam  C.
Pointer, Jr., formerly Chief Judge of the United States District Court  for
the  Northern District of Alabama (Lindsey, et al., v. Dow Corning, et al.,
CV-94-P-11558-S),  before  whom  all  federal  breast  implant  cases  were
consolidated  for pretrial purposes. The Revised Settlement arises  out  of
the class action settlement approved by the Court on September 1, 1994. All
appeals  from  the  Order  approving  the  Revised  Settlement  have   been
dismissed.  On January 16, 1996, the Company, Baxter Healthcare Corporation
and  Baxter International (collectively, Baxter), and Minnesota, Mining and
Manufacturing Company (3M) (hereinafter, the Settling Defendants) each paid
$125  million  into a court-established fund as an initial reserve  to  pay
claims  under  the Revised Settlement. The Company has made and  will  make
additional contributions to the court-established fund.

The  fifteen-year  Revised Settlement, which ends  on  December  15,  2010,
provides benefits to those U.S. breast implant recipients who have  had  at
least one breast implant manufactured by one of the Settling Defendants (or
their  related companies). For Current Claimants - those who submitted  the
proper documentation to the Claims Office in Houston by the 1994 deadline -
benefits  are  payable  regardless  of  the  number  of  claimants  seeking
compensation, and regardless of the total dollar value of approved  claims.
For  Other  and  Late Registrants - those who registered  with  the  Claims
Office  after  the Current Claimant deadline - benefits are subject  to  an
aggregate  $725  million limit for the three Settling Defendants  over  the
fifteen-year life of the program. The Company's individual aggregate  limit
for such benefits is $400 million, $27.6 million annually for the first ten
years,  and $24.8 million annually for the last five years. Amounts  unused
in one year may be rolled over to pay claims in ensuing years. In the event
the  dollar value of the claims subject to these limits were to exceed  the
amounts available to pay claims, claimants may be afforded additional  opt-
out  rights  but  without the right to assert punitive or  other  statutory
multiple  damage claims. The Company's obligations to make  payments  under
the  Revised  Settlement are not affected by the number  of  class  members
electing to opt out of the settlement or the number of class members making
claims under it except to the extent of the above-mentioned dollar limits.

In  addition to individual suits and the Lindsey class action, the  Company
is a defendant, together with other defendants, in a class action certified
on  April  11, 1996, in the Canadian province of British Columbia,  on  the
single issue of whether silicone gel breast implants are reasonably fit for
their  intended  purpose  (Harrington v. Dow Corning  Corporation  et  al.,
Supreme Court, British Columbia, C954330). A putative class action filed on
behalf  of  children  allegedly exposed to silicone in  utero  and  through
breast  milk  (Feuer,  et al., v. McGhan, et al., U.S.D.C.,  E.D.N.Y.,  93-
0146), which named all breast implant manufacturers and sought to establish
a medical monitoring fund, has been dismissed.

The  Company  entered  into several other settlements  of  breast  implant-
related  claims. In July of 1995, the Company entered into a $20.5  million
(U.S. funds) class action settlement with plaintiff representatives in  the
provinces of Ontario and Quebec. The class includes persons who have or had
MEC  breast  implants and who reside in Ontario and Quebec or who  received
their  MEC implants there. The settlement, which had minimal opt-outs,  has
been  approved by the provincial courts of Ontario and Quebec.  In  May  of
1996,  the Company, together with other Settling Defendants in the  Revised
Settlement  Program,  entered  into  a $50  million  settlement  of  claims

                                        9
<PAGE>

asserted  by  certain health insurers based upon payments made or  benefits
provided   by  insurers  and  represented  health  plans  to  participating
registrants  that  allegedly  involve or  relate  to  silicone  gel  breast
implants.  The  Company has contributed $22.5 million  to  the  settlement,
which  extinguishes  the  potential claims of  the  majority  of  the  U.S.
commercial and non-governmental health care insurer market against both the
defendants and settlement class members. In November 1996, the benefits  of
the  Revised  Settlement  were  extended, with  certain  modifications,  to
foreign  breast  implant  recipients.  Pursuant  to  this  settlement,  the
Settling  Defendants paid (on an equal basis) an aggregate of  $25  million
into a court-approved settlement fund as an initial reserve for payment  of
foreign claims.  On January 5, 2000, the Court advised the parties that the
foreign  settlement  was overfunded, and directed  the  transfer  of  $13.4
million  of  the $25 million fund to the Revised Settlement. The  Company's
share of the $13.4 million transferred was approximately $3 million.

The  Company's insurers were notified of the breast implant claims and  the
Revised  Settlement,  and  a  number  reserved  their  rights  or  declined
coverage.  The  Company reached settlement with many of these  insurers  in
connection with coverage litigation filed by it in state court in Texas. In
1993,  the  Company  offset  its breast implant product  liability  special
charges  by  $1.0  billion  of  expected insurance  proceeds  (recorded  as
Insurance  Recoverable). Because of its belief that additional  amounts  of
insurance  proceeds  above  that  amount will  be  recovered,  the  Company
recorded an additional Insurance Recoverable in the fourth quarter of  1998
of approximately $100 million.

While  there  have  been a few large judgments, defendants  have  won  more
trials  than  they have lost, and the Company's trial experience  has  been
mostly  favorable.  The Company has maintained throughout  this  litigation
that  breast implants do not cause disease, and medical and scientific data
support the Company's position. The Company's view has found support in the
trial  courts. Courts in several states have ruled to exclude the testimony
of plaintiffs' experts concerning a causal link between silicone gel breast
implants  and  systemic  illness on the ground that  it  fails  to  satisfy
standards  for reliability under current U.S. Supreme Court guidelines.  In
1998,  a  national science panel of four independent experts  appointed  by
Judge  Pointer issued its unanimous report, based on a comprehensive review
of the medical and scientific literature, that there is no evidence linking
silicone  breast implants and systemic disease.  Similarly,  in  1999,  the
Institute  of  Medicine  of  the  National  Academy  of  Sciences  -  while
commenting that the frequency of local injuries is greater than expected  -
concluded  there is insufficient evidence to link silicone breast  implants
with disease. The Company intends to dispose of the claims of remaining opt-
outs by continuing to implement its plan to settle cases at values it deems
acceptable,  and  to  wage a vigorous defense, including  taking  cases  to
trial, of those cases that do not settle at such values.

In  the  fourth  quarter of 1993, the Company recorded  a  charge  of  $500
million  before  taxes  ($310 million after taxes)  in  respect  of  breast
implant   cases.  The  charge  consisted  of  $1.5  billion  for  potential
liabilities  and  expenses, offset by $1.0 billion  of  expected  insurance
proceeds.  In  the  fourth quarters of 1994 and 1995, the Company  recorded
additional special charges of $750 million before taxes ($488 million after
taxes)   and  $950  million  before  taxes  ($590  million  after   taxes),
respectively,  related to breast implant product liability claims.  In  the
fourth  quarter of 1998, the Company recorded an additional special  charge
to  earnings  in the amount of $800 million before taxes and increased  its
insurance  receivable in the amount of $100 million,  resulting  in  a  net
charge to earnings of $433 million after taxes in respect of breast implant
product liability claims.

Prescription Drug Litigation
- ----------------------------

The  Company remains a defendant in several actions challenging pricing  on
brand  name  prescription  drugs. These actions include  several  currently
consolidated  antitrust actions brought against the Company and  more  than
thirty  other  pharmaceutical manufacturers, drug wholesalers and  pharmacy
benefit  managers  by  certain  chain drugstores,  supermarket  chains  and

                                        10
<PAGE>

independent  drugstores; state pharmaceutical actions; and purported  class
actions  on behalf of consumers. In the fourth quarter of 1998, the Company
recorded a special charge to earnings in the amount of $100 million  before
taxes  ($62  million  after  taxes) in respect of  this  prescription  drug
litigation. The Company will continue to defend vigorously its position  in
this  ongoing  litigation  and believes it will  be  able  to  address  all
remaining claims within its reserves.

Infant Formula Matters
- ----------------------

The Company, one of its subsidiaries, and others have been defendants in  a
number  of antitrust actions in various states filed on behalf of purported
statewide classes of indirect purchasers of infant formula products and  by
the  Attorneys General of Louisiana, Minnesota and Mississippi, alleging  a
price  fixing  conspiracy  and  other  violations  of  state  antitrust  or
deceptive  trade practice laws and seeking penalties and other relief.  The
Company  has resolved all of these actions except for a purported statewide
class  action  of indirect purchasers in Louisiana in which the  plaintiffs
filed  a  petition  for certiorari in the United States  Supreme  Court  on
jurisdictional  grounds  following the  United  States  Court  of  Appeals'
affirmation  of the district court's dismissal of such action. On  November
29, 1999, the United States Supreme Court granted the plantiffs' petition.

TAXOL* Litigation
- -----------------

There  is  no  composition  of  matter patent for  paclitaxel  (the  active
ingredient  in TAXOL*). In the United States, the Company is presently  the
only manufacturer and marketer of a product containing paclitaxel.  In 1997
and  1998,  the Company filed several lawsuits alleging that  a  number  of
generic  drug companies infringed its patents covering certain  methods  of
administering paclitaxel when they filed abbreviated new drug  applications
seeking  regulatory approval to sell paclitaxel. The generic  drug  company
defendants  are  Boehringer Ingelheim Corp.; Ben Venue Laboratories,  Inc.;
Bedford Laboratories; Immunex Corporation; Zenith Goldline Pharmaceuticals,
Inc.;    Ivax    Corporation;   Mylan   Pharmaceuticals,    Inc.;    Marsam
Pharmaceuticals, Inc.; and Schien Pharmaceuticals, Inc. These actions  were
consolidated  for  discovery in the United States District  Court  for  the
District  of  New  Jersey.  The Company does not assert  a  monetary  claim
against  any  of  the defendants, but seeks to prevent the defendants  from
marketing  paclitaxel in a manner that violates the Company's patents.  The
defendants  have  asserted that they do not infringe the Company's  patents
and that these patents are invalid and unenforceable.  Some defendants also
asserted  counterclaims seeking damages for alleged  antitrust  and  unfair
competition violations.

On  January  4,  2000, the District Court granted the Company's  motion  to
dismiss certain of the antitrust and unfair competition counterclaims.  The
Company's motion for summary judgment on the remaining antitrust and unfair
competition counterclaims was denied on March 17, 2000.

On  February  29,  2000, the District Court granted  in  part  the  generic
companies' summary judgment motions for invalidity by finding all claims of
the  Company's patents in dispute invalid, except for claims limited to the
treatment  of  ovarian  cancer. As a result of  this  ruling,  the  generic
companies  may obtain U.S. Food and Drug Administration approval to  market
paclitaxel  solely for treatment of metastatic breast cancer after  failure
of   combination  chemotherapy.  The  District  Court's  opinion  left  for
determination at trial the validity of the claims of the Company's  patents
directed  to  the  low dose, three-hour administration  of  paclitaxel  for
ovarian  cancer  and denied the generic companies' summary judgment  motion
arguing  non-infringement of the Company's patents. The Company may  pursue
its appeal rights in the future.


                                        11
<PAGE>

The claims remaining in the lawsuits are currently scheduled for trial in
May 2000.  It is not possible at this time to make a reasonable assessment
of the outcome of the remaining claims in these actions nor to reasonably
estimate the impact on TAXOL* sales or the amount of damages were the
Company not to prevail.

Environmental Matters
- ---------------------

The Company, together with others, is a party to, or otherwise involved in,
a  number of proceedings brought by the Environmental Protection Agency  or
comparable  state agencies under the Comprehensive Environmental  Response,
Compensation  and  Liability Act (CERCLA or Superfund) or comparable  state
laws directed at the cleanup of hazardous waste sites.


While  it  is not possible to predict with certainty the outcome  of  these
cases,  it is the opinion of management that they will not have a  material
adverse   effect   on  the  Company's  operating  results,   liquidity   or
consolidated financial position.


Item 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

None.

                                        12
<PAGE>

                                  PART IA
                               ------------

EXECUTIVE OFFICERS OF THE REGISTRANT
- ------------------------------------
The  following are the executive corporate officers and the other executive
officers of the Company:


                                Positions and Offices Presently
Name                      Age   Held with the Company
- ----                      ----  -----------------------------------

Charles A. Heimbold, Jr.   66   Chairman of the Board,Chief Executive
                                Officer and Director

Harrison M. Bains, Jr.     56   Treasurer and Vice President, Corporate Staff

Peter R. Dolan             44   President and Director

Donald J. Hayden, Jr.      44   Executive Vice President, E-Business and
                                Strategy, Corporate Staff

George P. Kooluris         55   Senior Vice President, Corporate Development,
                                Corporate Staff

Richard J. Lane            49   President, Worldwide Medicines Group

Sandra Leung               39   Secretary and Head  of  Office  of  Corporate
                                Conduct, Corporate Staff

John L. McGoldrick         59   President, Medical Devices Group and Executive
                                Vice President and General Counsel,Corporate
                                Staff

Michael F. Mee             57   Executive Vice President and Chief Financial
                                Officer, Corporate Staff

Christine A. Poon          47   President, International Medicines

Peter S. Ringrose, Ph.D.   53   Chief Scientific Officer and President,
                                Bristol-Myers Squibb Company Pharmaceutical
                                Research Institute

Stephen I. Sadove          48   President, Worldwide Beauty Care and
                                Nutritionals and Senior Vice President,
                                Corporate Staff

Frederick S. Schiff        52   Controller and Senior Vice President, Financial
                                Operations, Corporate Staff

John L. Skule              56   Senior Vice President, Corporate and
                                Environmental Affairs, Corporate Staff

Charles G. Tharp, Ph.D.    48   Senior Vice President, Human Resources,
                                Corporate Staff

Kenneth E. Weg             61   Vice Chairman and Director

                                        13
<PAGE>

     Persons  who hold titles as elected corporate officers of the  Company
were  last elected or reelected to the office held at the general  election
of  officers  by  the Company's Board of Directors on May  4,  1999  unless
otherwise indicated. Officers of the Company serve in such capacity at  the
pleasure of the Board of Directors of the Company.

     CHARLES  A.  HEIMBOLD,  JR.  - From 1992 to  1996,  President  of  the
Company.   Mr. Heimbold has been a director of the Company since 1989,  the
Chief Executive Officer of the Company since 1994 and Chairman of the Board
of Directors of the Company since 1995.

     HARRISON  M.  BAINS,  JR.  - Mr. Bains has  been  Treasurer  and  Vice
President, Corporate Staff of the Company since 1988.

     PETER R. DOLAN - From 1993 to 1995, President, Bristol-Myers Products,
a  division  of  the  Company, from 1995 to 1996, President,  Mead  Johnson
Nutritional Group, a division of the Company, from 1996 to 1997, President,
Nutritionals and Medical Devices Group, a division of the Company and  from
1997  to 1998, President, Pharmaceutical Group - Europe, a division of  the
Company,  and  from  1998  to  2000, Senior Vice  President,  Strategy  and
Organizational  Effectiveness,  Corporate  Staff.   Mr.  Dolan   has   been
President of the Company, a Director of the Company, a member of the Office
of  the  Chairman  and Chairman of the Corporate Operating Committee  since
January 2000.

     DONALD  J.  HAYDEN, JR. - From 1994 to 1995, Vice President &  General
Manager,  Bristol-Myers Oncology/Immunology Division,  a  division  of  the
Company,  in  1995,  President Oncology & Immunology,  a  division  of  the
Company,  from  1995  to 1997, Senior Vice President,  Worldwide  Franchise
Management  and Business Development, a division of the Company,  in  1997,
President, Intercontinental Pharmaceutical Group and Senior Vice President,
Worldwide  Business Development, Worldwide Medicines Group, a  division  of
the  Company,  from  1997  to 1998, President, Intercontinental,  Worldwide
Medicines  Group,  a  division of the Company  from  1998-2000,  President,
Worldwide Medicines Group, a division of the Company. Mr. Hayden  has  been
Executive Vice President of the Company and a member of the Office  of  the
Chairman since January 2000.

     GEORGE  P.  KOOLURIS  - Mr. Kooluris has been Senior  Vice  President,
Corporate Development, Corporate Staff of the Company since 1994.

     RICHARD  J.  LANE  -  From  1994 to 1995,  consultant  Schering-Plough
Corporation,  a  pharmaceutical company, in  1995,  Senior  Vice  President
Marketing    Operations,   Sandoz   Pharmaceuticals,   a    pharmaceutical,
nutritionals  and  chemicals  company,  from  1995  to  1997,  Senior  Vice
President  Marketing, U.S. Pharmaceuticals, a division of the  Company,  in
1997, President, U.S. Primary Care, a division of the Company, from 1997 to
1998, President, U.S. Pharmaceuticals, a division of the Company, and  from
1998 to 2000, President, U.S. Medicines and Global Pharmaceutical Group,  a
division  of the Company.  Mr. Lane has been President, Worldwide Medicines
Group,  a  division  of  the Company, and a member of  the  Office  of  the
Chairman since January 2000.

     SANDRA  LEUNG  -  From 1994 to 1996, Senior Staff Attorney,  Corporate
Staff, from 1996 to 1997, Assistant Counsel, Corporate Staff, from 1997  to
1999,  Associate Counsel, 1999, Counsel, Corporate Staff.   Ms.  Leung  has
been  Secretary,  Corporate  Staff, and Head of  the  Office  of  Corporate
Conduct  since  1999.  Ms.  Leung was elected to her  current  position  on
September 14, 1999.

     JOHN  L.  McGOLDRICK - From 1995 to 1997, General Counsel  and  Senior
Vice  President,  Corporate Staff of the Company and  from  1997  to  1998,
General  Counsel  and  Senior Vice President, Law and  Strategic  Planning,

                                        14
<PAGE>

Corporate  Staff  of  the  Company, and General  Counsel  and  Senior  Vice
President,  Corporate Staff of the Company and President,  Medical  Devices
Group,  a  division  of the Company, since 1998.  Mr. McGoldrick  has  been
Executive  Vice  President and General Counsel of the  Company,  President,
Medical  Devices  Group, a division of the Company, and  a  member  of  the
Office of the Chairman since January 2000.

     MICHAEL F. MEE - From 1994 to 2000, Chief Financial Officer and Senior
Vice President, Corporate Staff of the Company.  Mr. Mee has been Executive
Vice  President and Chief Financial Officer, Corporate Staff of the Company
and a member of the Office of the Chairman since January 2000.

     CHRISTINE  A. POON - From 1994 to 1995, President & General Manager  -
Canada, Pharmaceutical Group - Intercontinental, a division of the Company,
in 1995 Vice President OPS-Planning - Intercontinental & President, Canada,
a  division  of  the  Company, from 1995 to 1996, Vice President,  Northern
Region  Latin  America, Intercontinental, a division of the  Company,  from
1996  to  1997, Senior Vice President, Intercontinental Northern  Region  &
Canada,  a  division of the Company, in 1997, President, Latin America  and
Canada,  Worldwide  Pharmaceutical Group, a division  of  the  Company  and
President,  Medical Devices Group, a division of the Company from  1997  to
1998.   Ms.  Poon  has  been President, Intercontinental  Medicines  Group,
division of the Company since 1998.

     PETER  S.  RINGROSE, Ph.D. - From 1994 to 1996, Senior Vice President,
Worldwide  Discovery and Medicinal Research Development, Europe  of  Pfizer
Inc.,  a  health  care  company.  From 1997-2000, President,  Bristol-Myers
Squibb  Pharmaceutical Research Institute, a division of the Company.   Dr.
Ringrose  has been Chief Scientific Officer of the Company and a member  of
the Office of the Chairman since January 2000.

     STEPHEN I. SADOVE - From 1994 to 1996, President, Worldwide Clairol, a
division  of  the  Company, from 1996 to 1997, President, Worldwide  Beauty
Care,  a division of the Company.  Mr. Sadove has been President, Worldwide
Beauty  Care  and Nutritionals, a division of the Company, since  1997  and
Senior  Vice President, Corporate Staff since 1998.  Mr. Sadove has been  a
member of the Office of the Chairman since January 2000.

     FREDERICK  S.  SCHIFF  -  From  1990  to  1997,  Controller  and  Vice
President, Corporate Staff of the Company, from 1997 to 2000 Controller and
Vice  President, Financial Operations, Corporate Staff of the Company.  Mr.
Schiff has been Controller and Senior Vice President, Financial Operations,
Corporate Staff of the Company since March 2000.

     JOHN  L.  SKULE  - From 1993 to 1997, Vice President, Public  Affairs,
Corporate  Staff of the Company. Mr. Skule has been Senior Vice  President,
Corporate  and Environmental Affairs, Corporate Staff of the Company  since
1998.

     CHARLES  G.  THARP, Ph.D. - Dr. Tharp has been Senior Vice  President,
Human Resources, Corporate Staff of the Company since 1993.

     KENNETH  E.  WEG - From 1993 to 1996, President, Bristol-Myers  Squibb
Pharmaceutical  Group, a division of the Company, and from  1997  to  1998,
President,  Worldwide  Medicines Group, a  division  of  the  Company,  and
Executive Vice President of the Company from 1995 to 1999. Mr. Weg has been
a  Director  of  the  Company since 1995, a member of  the  Office  of  the
Chairman since 1998 and Vice Chairman of the Company since 1999.

     In addition to the positions and offices heretofore listed, all of the
foregoing executive corporate officers and other executive officers of  the
Company  are  directors and/or officers of one or more  affiliates  of  the
Company, with the exception of Mr. Skule and Dr. Tharp.


                                        15
<PAGE>

                                 PART II
                               ------------

Item 5. MARKET FOR THE REGISTRANT'S COMMON STOCK AND RELATED
        STOCKHOLDER MATTERS.


MARKET PRICES
- -------------

Bristol-Myers Squibb common and preferred stocks are traded on the New York
Stock  Exchange and the Pacific Exchange, Inc. (symbol: BMY).  A  quarterly
summary of the high and low market prices is presented below:

                                      1999                  1998
                              -----------------   -------------------
                              High        Low        High        Low

Common:

First Quarter                 $66 3/16      $58  1/2   $54  1/4   $44 29/32
Second Quarter                 70 7/16       57  7/16   59  7/32   49 19/32
Third Quarter                  75 15/16      64  5/8    62  19/32  48 15/16
Fourth Quarter                 77 15/16      60  1/8    66  29/32  46  1/8


Preferred:

There  were  no  trades of the  Company's preferred stock except  in  the
first quarter of 1999 and 1998 when the stock traded at a price of $1,000
and $906, respectively.


HOLDERS OF COMMON STOCK
- -----------------------

The  approximate number of record holders of common stock at December 31,
1999 was 120,358.

The  number of record holders is based upon the actual number of  holders
registered on the books of Bristol-Myers Squibb at such date and does not
include  holders  of  shares in "street names" or persons,  partnerships,
associations,  corporations  or  other entities  identified  in  security
position listings maintained by depository trust companies.

                                        16
<PAGE>

DIVIDENDS
- ----------------

Dividend payments per share in 1999 and 1998 were:

                               Common            Preferred
                         ------------------  ------------------

                            1999     1998     1999     1998
                         --------  --------  -------- -------
First Quarter            $.21 1/2  $.19 1/2   $.50     $.50
Second Quarter            .21 1/2   .19 1/2    .50      .50
Third Quarter             .21 1/2   .19 1/2    .50      .50
Fourth Quarter            .21 1/2   .19 1/2    .50      .50
                         --------  --------  -----    -----
                         $.86      $.78      $2.00    $2.00
                         =====     =====     =====    =====


In  December  1999,  the  Board of Directors  of  the  Company  declared  a
quarterly  dividend of $.245 per share on the common stock of the  Company,
payable  on  February 1, 2000 to shareholders of record as  of  January  8,
2000.  The  2000 indicated annual payment of $.98 per share represents  the
twenty-eighth consecutive year that the Company has raised the dividend  on
its common stock.

                                        17
<PAGE>

Item 6. SELECTED FINANCIAL DATA.

FIVE-YEAR FINANCIAL SUMMARY
OPERATING RESULTS
- -----------------
(in millions, except per share amounts)


                                 1999     1998     1997     1996     1995

Net Sales                     $20,222   $18,284  $16,701  $15,065  $13,767
                              -------   -------  -------  -------  -------
Expenses:
Cost of products sold          5,539     4,856    4,464    3,965    3,637
Marketing, selling and         4,578     4,418    4,173    3,925    3,670
administrative
Advertising and product        2,409     2,312    2,241    1,946    1,646
promotion
Research and development       1,843     1,577    1,385    1,276    1,199
Other(*)                          86       853     (44)     (60)    1,213
                              -------  -------  -------  -------  -------
                               14,455   14,016   12,219   11,052   11,365
                              -------  -------  -------  -------  -------
Earnings Before Income         5,767     4,268    4,482    4,013    2,402
Taxes(*)

Provision for income taxes     1,600     1,127    1,277    1,163      590
                              -------  -------  -------  -------  -------
Net Earnings(*)               $4,167    $3,141   $3,205   $2,850   $1,812
                               =====     =====    =====    =====    =====

Dividends paid on common
and preferred stock           $1,707    $1,551   $1,515   $1,507   $1,495

Earnings per common share -     2.10      1.58     1.61     1.42      .89
Basic(*)
Earnings per common share -     2.06      1.55     1.57     1.40      .89
Diluted(*)

Dividends per common share       .86       .78      .76      .75      .74


(*)  Includes  a  gain  on the sale of a business of $201  million  before
     taxes,  $125  million after taxes, in 1998; and $225  million  before
     taxes,  $140 million after taxes, in 1997. Includes a special  charge
     for  prescription  drug  pricing litigation of  $100  million  before
     taxes,  $62 million after taxes, or $.03 per common share, basic  and
     diluted,  in 1998. Includes a special charge for pending  and  future
     product  liability claims of $700 million before taxes, $433  million
     after  taxes,  or $.22 per common share, basic, and $.21  per  common
     share,  diluted,  in  1998; $950 million before taxes,  $590  million
     after  taxes,  or $.29 per common share, basic and diluted  in  1995.
     Includes a provision for restructuring of $201 million before  taxes,
     $125  million after taxes, in 1998; $225 million before  taxes,  $140
     million  after  taxes, in 1997; and $310 million before  taxes,  $198
     million after taxes, in 1995.

                                        18
<PAGE>

Item 6. SELECTED FINANCIAL DATA. (Con't.)

FIVE-YEAR FINANCIAL SUMMARY
FINANCIAL POSITION AT DECEMBER 31
- ---------------------------------
(in millions, except per share amounts)

                                  1999      1998    1997    1996    1995

Current assets                  $9,267    $8,782  $7,736  $7,528  $7,018
Property, plant and equipment    4,621     4,429   4,156   3,964   3,760

Total assets                    17,114    16,272  14,977  14,685  13,929

Current liabilities              5,537     5,791   5,032   5,050   4,806
Long-term debt                   1,342     1,364   1,279     966     635
Total liabilities                8,469     8,696   7,758   8,115   8,107

Stockholders' equity            $8,645    $7,576  $7,219  $6,570  $5,822

Average common shares            1,984     1,987   1,992   2,007   2,024
outstanding - Basic

Average common shares
outstanding - Diluted            2,027     2,031   2,042   2,035   2,032


Reference  is  made  to  Note  2 Acquisitions  and  Divestitures,  Note  7
Property,  Plant  and Equipment and Note 15 Litigation, appearing  in  the
Notes to Consolidated Financial Statements included in Part II, Item 8  of
this Form 10-K Annual Report.

                                        19
<PAGE>

Item  7.MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL  CONDITION  AND
RESULTS OF OPERATIONS.

Summary

In 1999, Bristol-Myers Squibb surpassed $20 billion in annual global sales
and achieved record levels of sales and  earnings. All four of the Company's
business segments achieved record levels  of sales, bringing the worldwide
sales to $20.2 billion, an 11% increase  over 1998. Domestic sales,
representing 63% of worldwide  sales, increased 15% to $12.8 billion, while
international sales increased 3%  to $7.4 billion. Sales growth resulted from
a 9% increase due to volume and a 2% increase from changes in selling prices.
Exchange rate fluctuations had no  effect on worldwide sales, but did have an
unfavorable effect of 2% on international  sales,  primarily  due  to  Latin
American and European currencies.

The  Company's most important product lines experienced double-digit sales
increases  on  a  worldwide  basis. In fact, three  products,  PRAVACHOL*,
TAXOL* (paclitaxel) and GLUCOPHAGE exceeded $1 billion in sales, while six
additional  products  exceeded over one-half  billion  dollars  in  annual
sales.  Bristol-Myers  Squibb had 64 product  lines  with  more  than  $50
million  in  annual  sales, including 35 with more than  $100  million  in
annual sales.

Earnings  before income taxes, excluding the 1998 special charge described
below, increased 14% to $5.8 billion in 1999. Net earnings, on this basis,
increased  15% to $4.2 billion; basic and diluted earnings per share  each
increased  15% to $2.10 and $2.06, respectively. Over the past five  years
net  earnings  and diluted earnings per share, excluding special  charges,
have   increased  at  compound  annual  growth  rates  of  12%  and   13%,
respectively. In 1999, the Company reported 15% diluted earnings per share
growth  over  the  prior  year for each of the first  three  quarters  and
excluding  the  1998  special charge, a 16%  growth  rate  in  the  fourth
quarter.

In  1999, consistent with the mission of the Company to extend and enhance
human life and develop the highest quality  products, the Company invested
more than $1.8 billion in research and  development, a 17% growth over the
prior year  and  growing  at  an annualized  rate  of  11%  over  the  past
five  years.  This  continuing investment  has  led to the discovery of
innovative new products  and  the development  of  new indications for
existing products including:  VANLEV* (omapatrilat),  a  novel  cardiovascular
compound  for  the  treatment  of hypertension, which is the first
antihypertensive ever to receive priority review  from  the  U.S.  Food  and
Drug Administration  (FDA)  under  the Prescription  Drug  User  Fee  Act;
a  GLUCOPHAGE/glyburide  product  and  GLUCOPHAGE  XR  Extended Release
Tablets, both for  diabetes;  VANIQA*,  a topical treatment for excessive facial
hair in women; TEQUIN*, an advanced antibiotic  for the treatment of multiple
common infections; an easier-to-digest, enteric-coated treatment form of VIDEX*
for HIV/AIDS; and TAXOL*,for adjuvant treatment of node-positive breast cancer.

Bristol-Myers Squibb's financial position remains strong. At December  31,
1999, the Company held almost $3.0 billion in cash, time deposits and
marketable securities. Cash provided by operating  activities reached $4.5
billion, the highest  in  the  last  10 years.  Returns  to shareholders
included dividend distributions  of  $1.7 billion and stock repurchases of
$1.4 billion. Dividends per common  share were  $.86  in  1999, increasing
from $.78 per share  paid  in  1998.  The Company has continued to lower its
dividend payout ratio, which represents cash  dividends  paid  per common
share divided by  diluted  earnings  per common  share, that amounted to 42%,
43% and 48% in 1999, 1998  and  1997, respectively,  excluding the 1998
special charge. In  December  1999,  the Company  announced  a  dividend
increase, the 28th consecutive  year  that dividends  have  increased,  and
expanded  the  share  repurchase  program authorization  by  an  additional
$2 billion. The  2000  indicated  annual payment  is  $.98 per common share,

                                        20
<PAGE>

a 14% increase over 1999, following  a 10% dividend increase in 1999. As
further evidence of its strong financial position,  Bristol-Myers  Squibb is
one  of  only  seven  U.S.  industrial companies  to  receive  a triple-A
credit rating  from  both  Moody's  and Standard & Poor's.

Net Sales and Earnings

Worldwide  sales  increased 11% in 1999 to $20.2  billion,  compared  with
increases  of  9% and 11% in 1998 and 1997, respectively. The consolidated
sales  growth  in  1999 resulted from a 9% increase due to  volume,  a  2%
increase  due  to changes in selling prices and no change due  to  foreign
exchange rate fluctuations. In 1998, the 9% increase in sales reflected  a
10%  increase  due to volume, a 3% decrease due to foreign  exchange  rate
fluctuations and a 2% increase due to changes in selling prices. In  1997,
the  11%  increase in sales reflected a 14% increase due to volume,  a  3%
decrease due to foreign exchange rate fluctuations and no changes  overall
from pricing activity. Domestic sales increased 15% in both 1999 and 1998,
and  14%  in  1997, while international sales increased  3%  in  1999  (5%
excluding  foreign  exchange), 2% in 1998 (9% excluding foreign  exchange)
and  7%  in  1997  (15%  excluding  foreign  exchange).  In  general,  the
businesses of the Company's industry segments are not seasonal.

Earnings  before income taxes, excluding the 1998 charge described  below,
increased 14% to $5,767 million from $5,068 million in 1998. Net  earnings
on  this  basis increased 15% to $4,167 million compared to $3,636 million
in 1998. Basic earnings per share increased 15% to $2.10 from $1.83 in the
prior  year  and diluted earnings per share increased 15%  to  $2.06  from
$1.79.  Net earnings margins, excluding the 1998 special charge, increased
to  20.6%  in  1999 from 19.9% in 1998. As described in the notes  to  the
financial statements, in the fourth quarter of 1998, the Company  recorded
a  special charge of $800 million before taxes, $495 million after  taxes,
or  $.24  per  diluted share, to augment the reserve  for  breast  implant
liability and for prescription drug pricing litigation, offset by expected
insurance recoveries. The breast implant component of the charge was  $700
million  before  taxes  ($800  million of liability  offset  by  insurance
receivables of $100 million), and the prescription drug pricing  component
was $100 million before taxes. As a result of the special charge, 1998 net
earnings  were  $3,141 million, basic earnings per share  were  $1.58  and
diluted  earnings  per share were $1.55. In 1998, net earnings,  excluding
the  1998  special charge, were $3,636 million, a 13% increase over  1997.
Basic  earnings per share were $1.83 and diluted earnings per  share  were
$1.79, both increasing 14% over 1997. Net earnings margins, excluding  the
special charge, increased to 19.9% in 1998 from 19.2% in 1997.

The effective income tax rate on earnings before income taxes was 27.7% in
1999,  compared to 28.3% in 1998, excluding the special charge, and  28.5%
in  1997.  The effective income tax rate has decreased since 1997  due  to
increased income in lower tax rate jurisdictions.

As  described in Note 2 to the financial statements, in 1999, the  Company
acquired  CAL-C-TOSE*,  a  leading nutritional milk  modifier  product  in
Mexico.  In 1998, the Company acquired Redmond Products, Inc.,  a  leading
hair  care  manufacturer in the U.S. In 1998, the  Company  also  acquired
Phytoervas,  a  line of premium retail hair care products in  Brazil,  and
Dong-A  Biotech  Co., Ltd., a marketer and distributor  of  pharmaceutical
products in South Korea. In 1997, the Company acquired Abeefe S.A., Peru's
largest  pharmaceutical manufacturer and marketer. The  Company  also,  in
1997,  acquired  CHOCO  MILK*,  Mexico's  leading  milk-based  nutritional
supplement, and SAL DE UVAS PICOT*, a leading effervescent antacid product
in Mexico.

As  described in Note 2 to the financial statements, in the fourth quarter
of  1999,  the  Company completed the sale of Laboratori  Guieu,  SpA,  an
Italian-based   gynecological,  pediatric  and   dermatological   products
business. In the first quarter of 1998, the Company divested its Ban brand
of  anti-perspirants and deodorants. In the second quarter  of  1998,  the
Company  divested  A/S  GEA, a Denmark-based generic  drug  business,  and

                                        21
<PAGE>

Hexachimie,  a  specialty chemical manufacturer based in  France.  In  the
fourth  quarter  of 1997, the Company divested Linvatec  Corporation,  its
arthroscopy and powered surgical instrument business.

In  January  2000, the Company announced its intention to sell its  Matrix
Essentials,  Inc.  subsidiary, a manufacturer of  professional  hair  care
products sold exclusively through beauty salons.

Expenses

Total costs and expenses, as a percentage of sales, improved over the last
three  years  to 71.5% in 1999 compared with 72.3% in 1998, excluding  the
1998 special charge, and 73.2% in 1997.

As a percentage of sales, cost of products sold increased to 27.4% in 1999
compared to 26.6% in 1998, principally due to sales growth of lower margin
products  from  the  Oncology  Therapeutics  Network  (OTN),  a  specialty
distributor of anti-cancer medicines and related products. In  1998,  cost
of  products  sold as a percentage of sales remained at the  prior  year's
level  of  26.6% compared to 26.7% in 1997. Accordingly, the  Company  has
maintained  its  cost of goods sold as a percentage of sales  consistently
over the last three years, excluding
its oncology distribution business.

Advertising  and promotion expenses increased 4% over the  prior  year  to
$2,409  million  in  1999,  primarily due  to  the  continued  support  of
PRAVACHOL*, EXCEDRIN*, GLUCOPHAGE and PLAVIX in the Medicines segment  and
for  promotional  campaigns related to existing products and  new  product
launches  in the Beauty Care and Nutritional segments, including ENFAMIL*,
BOOST*,  ULTRESS*, VIACTIV* Soft Calcium Chews and AUSSIE LAND*. In  1998,
advertising  and  promotion expenses increased 3% to $2,312  million  from
$2,241  million  in  1997.  As  a percentage  of  sales,  advertising  and
promotion expenses decreased to 11.9% in 1999 from 12.6% in 1998 and 13.4%
in 1997, reflecting an improvement in the effectiveness of the advertising
and  promotion  spending.  This  decreasing  trend  is  primarily  due  to
reductions  in  direct-to-consumer advertising and  increases  in  medical
education efforts in the Medicines segment.

Marketing, selling and administrative expenses, as a percentage of  sales,
decreased  to  22.6% in 1999 from 24.2% in 1998 and 25.0%  in  1997.  This
decreasing  trend  is a result of slower rates of increase  in  marketing,
sales  force  and general administrative expenses as compared  to  revenue
increases in the same period.

The  Company's  investment  in  research and  development  totaled  $1,843
million in 1999, an increase of 17% over 1998, and an increase to 9.1%  in
1999  as  a percentage of sales, from 8.6% in 1998 and 8.3% in 1997.  This
spending level reflects the Company's commitment to research over a  broad
range  of  therapeutic areas and to clinical development of new  products.
Over the past five years, research and development expenses have increased
at a compound annual growth rate of 11%. In 1999, research and development
spending dedicated to pharmaceutical products increased 18%, and was 12.6%
of  pharmaceutical  sales compared to 12.4% and 12.0% in  1998  and  1997,
respectively.

In  1999,  eight regulatory approvals were obtained and 10  dossiers  were
filed in the U.S. Most notably, in December 1999, the Company received FDA
approval for TEQUIN*, an advanced antibiotic for the treatment of multiple
common  infections, including those of the respiratory tract. The  Company
also   received  marketing  clearance  for  new  indications  for  several
products,  including: in October 1999, the use of TAXOL* by injection  for
adjuvant  treatment  of  node-positive breast  cancer  following  standard
chemotherapy; and, in September 1999, ZERIT* and VIDEX* were approved  for
use  as  first-line  components  of a combination  antiretroviral  therapy
regimen  for HIV-infected patients. In January 2000, the Company submitted
a New Drug Application (NDA) for VIDEX* (didanosine) a once-daily, easier-
to-digest,  enteric-coated form of VIDEX*. In December 1999,  the  Company

                                        22
<PAGE>

submitted  a filing for VANLEV* (omapatrilat) in the U.S., European  Union
and Canada. VANLEV* is the most clinically developed member of a new class
of  cardiovascular compounds developed for the treatment of  hypertension.
In 1999, the Company also initiated filings to gain marketing approval for
two  antidiabetic  drugs - a new oral antidiabetic combination  drug  that
leverages   the  benefits  of  two  widely  prescribed  oral  antidiabetic
medications,  GLUCOPHAGE  (metformin) and  glyburide,  a  well-established
sulfonylurea  antidiabetic,  and GLUCOPHAGE XR  (metformin  hydrochloride)
Extended  Release Tablets, a once-daily version of GLUCOPHAGE. A  NDA  for
VANIQA*, a topical treatment for excessive facial hair in women, was filed
in  September  1999. In 1999, the Company announced a number  of  research
alliances,  collaborations  and commercialization  agreements  with  other
companies,  including a development, commercialization  and  collaboration
agreement with Otsuka Pharmaceutical Co., Ltd., for aripiprazole, a  novel
drug under study in Phase III trials as a treatment for schizophrenia;  an
alliance  with  Millennium  Predictive Medicine,  Inc.,  a  subsidiary  of
Millennium  Pharmaceutical,  Inc.,  in  the  emerging  field   of   cancer
pharmacogenomics;  and  a licensing agreement and  research  collaboration
with OXiGENE, Inc., to develop and commercialize combretastatin anti-tumor
vascular targeting agents.

The  Company recorded $201 million and $225 million in gains from the sale
of businesses in 1998 and 1997,
respectively.  The  Company also recorded restructuring  charges  of  $201
million  in  1998  and  $225 million in 1997. These restructuring  charges
consisted  primarily  of  asset  write-downs  and  employee-related  costs
related to the consolidation and closure of plants and facilities.

Business Segments

All  four  of  the Company's business segments - Medicines,  Beauty  Care,
Medical  Devices  and Nutritionals - reported sales increases  during  the
year.

Sales  in  the Medicines segment (Pharmaceuticals and Consumer Medicines),
which  is  Bristol-Myers Squibb's largest segment  at  71%  of  the  total
Company,  increased 14% to $14,309 million in 1999. Sales growth  resulted
from  a  12% increase due to volume and a 3% increase from selling prices,
offset  by  a  1%  decrease  due to the effect of  foreign  exchange  rate
fluctuations.  Domestic  sales  increased  23%  and  international   sales
increased 5%, excluding foreign exchange, primarily due to volume growth.

Sales  of PRAVACHOL*, the Company's largest selling product, increased  4%
to $1,704 million. International sales increased 8% (10% excluding foreign
exchange) to $671 million. Domestic sales increased 1% to $1,033  million,
reflecting  intensifying  competition. The  product's  U.S.  market  share
leveled  off  at 15% for the year. In 1999, the results of the Prospective
Pravastatin Pooling Project, the largest statin drug analysis, found  that
PRAVACHOL* consistently helps reduce the risk of recurrent coronary events
in  women,  older  patients and patients with diabetes. The  Company  also
announced  the  launch of the Pravastatin or Atorvastatin  Evaluation  and
Infection Therapy, or PROVE IT, trial, the first major clinical  trial  to
compare  the effects of PRAVACHOL* versus Lipitor in reducing the risk  of
heart attacks and other cardiac events. This clinical trial also seeks  to
further examine the role of infection in atherosclerosis.

Sales of TAXOL*, the Company's leading anti-cancer agent, increased 23% to
$1.5  billion  as the product continued to benefit from increased  use  in
ovarian,   breast  and  non-small  cell  lung  cancer  following  standard
chemotherapy.  In  October 1999, the FDA approved the  use  of  TAXOL*  by
injection  for adjuvant treatment of node-positive breast cancer following
standard  chemotherapy.  There  is no composition  of  matter  patent  for
paclitaxel  (the active ingredient in TAXOL*). In the United  States,  the
Company  is  presently  the only manufacturer and marketer  of  a  product
containing  paclitaxel.   In  1997 and 1998,  the  Company  filed  several
lawsuits  alleging that a number of generic drug companies  infringed  its
patents  covering  certain methods of administering paclitaxel  when  they

                                        23
<PAGE>

filed  abbreviated  new drug applications seeking regulatory  approval  to
sell  paclitaxel. The defendants have asserted that they do  not  infringe
the   Company's   patents  and  that  these  patents   are   invalid   and
unenforceable.   Some  defendants  also  asserted  counterclaims   seeking
damages for alleged antitrust and unfair competition violation. On January
4,  2000,  the  District  Court granted the Company's  motion  to  dismiss
certain  of  the  antitrust  and  unfair  competition  counterclaims.  The
Company's  motion  for  summary judgment on the  remaining  antitrust  and
unfair competition counterclaims was denied on March 17, 2000. On February
29,  2000,  the  District  Court granted in part  the  generic  companies'
summary  judgment  motions for invalidity by finding  all  claims  of  the
Company's  patents in dispute invalid, except for claims  limited  to  the
treatment  of  ovarian  cancer. As a result of this  ruling,  the  generic
companies may obtain U.S. Food and Drug Administration approval to  market
paclitaxel solely for treatment of metastatic breast cancer after  failure
of  combination  chemotherapy.  The  District  Court's  opinion  left  for
determination at trial the validity of the claims of the Company's patents
directed  to  the  low dose, three-hour administration of  paclitaxel  for
ovarian  cancer and denied the generic companies' summary judgment  motion
arguing non-infringement of the Company's patents. The Company may  pursue
its  appeal rights in the future. The claims remaining in the lawsuits are
currently  scheduled for trial in May 2000.  It is not  possible  at  this
time  to  make  a  reasonable assessment of the outcome of  the  remaining
claims  in  these actions nor to reasonably estimate the impact on  TAXOL*
sales or the amount of damages were the Company not to prevail.

GLUCOPHAGE sales increased 53% to $1,317 million. GLUCOPHAGE, the  leading
branded  oral medication for treatment of non-insulin dependent  (type  2)
diabetes,  had a 1999 market share of 31.3%, up from 26.9%  in  the  prior
year. In May 1999, the FDA approved AVANDIA in combination with GLUCOPHAGE
for  the  treatment of type 2 diabetes. AVANDIA is a product of SmithKline
Beecham, and is being co-promoted by Bristol-Myers Squibb in the U.S.  The
Hatch-Waxman  legislation exclusivity for GLUCOPHAGE expires in  September
2000.

PLAVIX,  a  platelet  aggregation inhibitor for the reduction  of  stroke,
heart attack and vascular death in atherosclerotic patients, reached sales
of  $547 million for the year compared to $144 million in the prior  year.
Sales  of AVAPRO, an angiotensin II receptor blocker for the treatment  of
hypertension,  increased  107%  to $255 million.  AVAPRO  and  PLAVIX  are
cardiovascular  products that were launched from the Bristol-Myers  Squibb
and Sanofi S.A. joint venture.

Sales  of  ZERIT*  and  VIDEX*, the Company's two anti-retroviral  agents,
increased  10%  to  $605  million and 27% to $205  million,  respectively.
ZERIT*  is  the  most  commonly  prescribed thymidine  nucleoside  reverse
transcriptase  inhibitor in HIV therapy in the U.S. In  1999,  ZERIT*  and
VIDEX* received regulatory approvals for use as first-line components of a
combination  antiretroviral  therapy regimen  for  HIV-infected  patients.
Also, in November, the FDA approved once-daily dosing for VIDEX*.

Sales of BUSPAR*, the Company's novel anti-anxiety agent, increased 14% to
$605  million, while sales of SERZONE*, a novel antidepressant,  increased
29%  to  $332 million. The exclusivity period for BUSPAR* expires  in  May
2000.

Sales  of  PARAPLATIN*,  which  is used in  combination  therapy  for  the
treatment of ovarian cancer, increased 14% to $600 million.

Sales  of  CEFZIL*,  an  oral  cephalosporin  used  in  the  treatment  of
respiratory  infections  and sinusitis, increased  12%  to  $402  million.
MONOPRIL*,   a  second-generation  angiotensin  converting  enzyme   (ACE)
inhibitor with once-a-day dosing, had increased sales of 12% reaching $424
million.

                                        24
<PAGE>

Sales  from the Oncology Therapeutics Network, a specialty distributor  of
anti-cancer medicines and related products, reached $894 million  for  the
year, an increase of 36% over 1998.

International   sales   of   MAXIPIME*,  a  fourth-generation   injectable
cephalosporin, increased 28% to $133 million. Effective January  1,  1999,
Dura   Pharmaceuticals,   Inc.  was  appointed  the   exclusive   domestic
distributor for MAXIPIME*.

Sales  of  EXCEDRIN*  remained at prior year levels of  $240  million.  In
October 1999, the FDA expanded the EXCEDRIN* Migraine indication from  the
treatment  of mild to moderate migraine pain to encompass the severe  pain
and  associated symptoms of the full migraine syndrome. Sales of BUFFERIN*
increased 18% to $147 million due to increased sales in Japan, while sales
of  EFFERALGAN*,  an  effervescent analgesic  sold  primarily  in  France,
increased 9% to $166 million.

Sales  of  captopril, an ACE inhibitor sold primarily under the  trademark
CAPOTEN*,  declined  24%  to  $484 million  due  to  the  loss  of  patent
exclusivity in international markets.

In 1998, Medicines segment sales increased 12% over 1997 levels. Increases
in  sales  of PRAVACHOL*, TAXOL*, PARAPLATIN*, ZERIT*, MONOPRIL*, BUSPAR*,
CEFZIL*,  GLUCOPHAGE, SERZONE*, VIDEX*, AVAPRO, PLAVIX and EXCEDRIN*  were
partially offset by decreases in sales of CAPOTEN*.

The  margin on earnings before taxes in the Medicines segment improved  to
28.1% in 1999 from 27.1% in 1998, as reductions, as a percentage of sales,
in  sales  force  expenditures, advertising  and  promotion  spending  and
general administrative expenses were partially offset by increases in cost
of  products sold. In 1998, the margin on earnings before taxes  of  27.1%
remained  at the prior year level as increases in research and development
and  sales force expenditures were offset by decreases in advertising  and
promotional spending and general administrative expenses.

Sales  in  the Beauty Care segment increased 3% in 1999 to $2,381 million,
reflecting a 2% increase due to volume, a 2% increase due to pricing and a
1% decrease due to foreign exchange rate fluctuations. International sales
increased  7%  (9% excluding the effect of foreign exchange) and  domestic
sales increased 1%. A softening in market demand in combination with other
operating  factors, including the introduction of a new demand  management
manufacturing  system,  slowed domestic shipments  during  the  year.  The
Company's  Clairol division continues to be the number one  hair  products
Company  in  the  U.S.  Hair  care product sales  increased  6%  in  1999,
primarily  due to sales of the HERBAL ESSENCES* complete line of shampoos,
conditioners, styling aids, body wash and facial care. Sales of the HERBAL
ESSENCES*  line  increased 14% to $637 million due to the  launch  of  the
HERBAL ESSENCES* facial care line in the U.S. and the launch of the HERBAL
ESSENCES* hair care line in Japan, Germany and Brazil. HERBAL ESSENCES* is
the  number three brand in the total shampoo and conditioner market in the
U.S.,  and  is number four in body wash. Sales of DAILY DEFENSE* increased
44% to $118 million following its launch into international markets. Sales
of  AUSSIE* products were $124 million, an increase of 15% over the  prior
year.  Haircolor sales increased 1% with increases in NICE 'N EASY* of  3%
to  $187  million  and NATURAL INSTINCTS* of 9% to $94 million,  partially
offset by a decrease of 8% in HYDRIENCE* to $92 million.

In  1998, sales in the Beauty Care segment increased 22% from 1997 levels,
primarily  due  to increased sales of hair care products,  led  by  HERBAL
ESSENCES*.

The  margin on earnings before taxes in the Beauty Care segment  decreased
to  10.4% in 1999, from 14.9% in 1998, primarily due to an increase, as  a
percentage  of  sales,  in cost of products sold reflecting  a  change  in

                                        25
<PAGE>

product  mix,  higher  levels  of  operating  costs,  and  slower  product
shipments  compared to the prior year. Increased promotional  expenditures
for new product introductions and support for existing products, including
ULTRESS*  and AUSSIE LAND*, also contributed to the decline. In 1998,  the
margin  on  earnings  before taxes improved to 14.9% from  14.2%  in  1997
primarily  due to higher volumes and manufacturing efficiencies, partially
offset by investment spending behind new product introductions.

Sales  in  the  Medical Devices segment increased 4%  to  $1,682  million,
excluding  sales from a 1998 distribution agreement with the  acquirer  of
Zimmer's  divested  arthroscopy and powered surgical instrument  business.
Including the sales from the 1998 distribution agreement, Medical  Devices
sales  increased 2%, reflecting a 1% increase due to volume, a 1% increase
due  to  the  effect  of foreign exchange and no effect  from  changes  in
selling  prices.  Domestic  sales increased  2%  and  international  sales
increased  3%  (1%  excluding the effect of foreign  exchange).  Worldwide
sales  of  knee  prosthetic joint replacements  in  the  Company's  Zimmer
division  increased  11%  and hip replacement  sales  increased  12%.  The
Company's ConvaTec division is the worldwide market share leader in ostomy
and  advanced  wound care products. ConvaTec sales decreased  1%  to  $719
million  while remaining at prior year levels excluding foreign  exchange.
Sales  of  ostomy products decreased 3% and sales of wound  care  products
were slightly below prior year levels.

In  1998,  worldwide sales in the Medical Devices segment,  excluding  the
December  1997  divestiture of Zimmer's arthroscopy and  surgical  powered
instrument business, increased 7%.

The  margin  on  earnings  before taxes in  the  Medical  Devices  segment
improved  to 21.7% in 1999 from 20.4% in 1998, primarily due to a decrease
in  cost of products sold as a result of improved manufacturing processes.
The  margin  on  earnings  before taxes in  the  Medical  Devices  segment
improved  to  20.4%  in 1998 from 19.1% in 1997, due to  decreases,  as  a
percentage  of  sales,  in  other  marketing  and  general  administrative
expenses,  partially offset by increases in cost of products sold  due  to
higher  costs  for products sold under a distribution agreement  with  the
acquirer of Linvatec.

Sales  in  the  Nutritionals  segment  increased  5%  to  $1,850  million,
reflecting a 5% increase due to volume, a 1% decrease due to the effect of
foreign  exchange rate fluctuations primarily in Latin America  and  a  1%
increase  due to changes in selling prices. International sales  increased
2%  (5%  excluding  the effect of foreign exchange),  and  domestic  sales
increased 7%. Mead Johnson continues to be the leader in the worldwide and
U.S.  infant formula markets. Total infant formula sales increased  2%  to
$1,233  million  (3% excluding foreign exchange). Sales of  ENFAMIL*,  the
Company's  largest selling infant formula, increased 9%  to  $735  million
worldwide. Adult consumer nutritional sales increased 27% as a result of a
32% increase in sales of BOOST*, and $29 million in sales of VIACTIV* Soft
Calcium Chews launched in December 1998.

In  1998,  worldwide sales of Nutritionals decreased 2% from 1997  levels,
primarily  due  to decreases in infant formula sales partially  offset  by
growth of NUTRAMIGEN*, LACTO FREE*, BOOST* and CHOCO MILK*.

The  margin on earnings before taxes in the Nutritionals segment decreased
to  20.3%  in  1999  from  21.1%  in  1998,  primarily  due  to  increased
advertising  and promotion expenditures for ENFAMIL*, BOOST* and  VIACTIV*
Soft   Calcium  Chews.  The  margin  on  earnings  before  taxes  in   the
Nutritionals segment improved to 21.1% in 1998 from 20.1% in 1997  due  to
decreases,  as a percentage of sales, in cost of products sold,  resulting
from improved manufacturing efficiencies.

Geographic Areas

Bristol-Myers Squibb products are available in virtually every country  in

                                        26
<PAGE>

the  world;  its largest markets are the U.S., France, Japan, Germany  and
Canada.

Sales  in  the  United States, net of inter-area sales, increased  15%  in
1999.  Sales in the Medicines and Beauty Care segments comprised  72%  and
12%,  respectively, of the region's sales. Products with strong growth  in
the   region  included  GLUCOPHAGE,  TAXOL*,  ENFAMIL*,  BUSPAR*,  PLAVIX,
PARAPLATIN*  and AVAPRO. The margin on earnings before taxes decreased  to
24.2%  in  1999  from  25.3% in 1998 primarily  due  to  increases,  as  a
percentage  of  sales, in cost of products sold. In  1998,  sales  in  the
United  States  increased 15%, net of inter-area sales, primarily  due  to
growth  of  products  from  the  Medicines segment  including  GLUCOPHAGE,
TAXOL*,  PRAVACHOL* and hair care products from the Beauty  Care  segment.
The  margin on earnings before taxes increased to 25.3% in 1998 from 23.4%
in  1997 primarily due to decreases, as a percentage of sales, in cost  of
products sold, advertising and general administrative expenses.

Sales  in  Europe, Mid-East and Africa, net of inter-area sales, increased
2% (4% excluding foreign exchange). The Medicines segment comprised nearly
79%  of  sales  in the region. Products with strong growth in  the  region
included  PRAVACHOL*, TAXOL*, PLAVIX, AVAPRO and DAILY DEFENSE*. Increases
in  sales of these products were partially offset by decreases in sales of
ostomy  supplies  and  of  CAPOTEN*, due to the loss  of  exclusivity  and
generic  competition.  The margin on earnings before  taxes  increased  to
25.2%  in  1999 from 23.4% in 1998, primarily due to improved sales  force
effectiveness as evidenced by lower sales force expense, as  a  percentage
of  sales,  and  a  decrease in promotional expenses. In  1998,  sales  in
Europe,  Mid-East  and Africa, net of inter-area sales, increased  4%  (6%
excluding  foreign  exchange), due to sales growth of products,  including
TAXOL*,  ZERIT*,  PRAVACHOL* and HERBAL ESSENCES*.  These  increases  were
partially  offset  by  decreases in sales  of  CAPOTEN*  due  to  loss  of
exclusivity.  The margin on earnings before taxes decreased  to  23.4%  in
1998  from  23.8% in 1997 due to increases, as a percentage of  sales,  in
promotional expenses.

Sales  in Other Western Hemisphere countries, net of inter-area sales  and
excluding foreign exchange, increased 6% in 1999. The Medicines and Beauty
Care  segments comprised nearly 57% and 21%, respectively, of the region's
sales.  Including foreign exchange, sales decreased 5% primarily resulting
from  decreases in sales of CAPOTEN* and PRAVACHOL*, partially  offset  by
growth  in HERBAL ESSENCES*, ENFAMIL*, DAILY DEFENSE*, AVAPRO and  PLAVIX.
The  margin on earnings before taxes decreased to 6.5% in 1999 from  12.8%
in  1998  as  a result of the currency devaluation in Brazil and  regional
economic  downturns. In 1998, sales in Other Western Hemisphere countries,
net  of  inter-area sales, increased 11% (20% excluding foreign exchange),
due to the introduction of HERBAL ESSENCES* and CHOCO MILK* to the region.
The  margin on earnings before taxes decreased to 12.8% in 1998 from 14.2%
in  1997,  reflecting  increases, as a percentage of  sales,  in  cost  of
products sold.

Sales  in  the Pacific region, net of inter-area sales, increased  17%  in
1999  (8%  excluding foreign exchange). The favorable effect from  foreign
exchange   was   primarily  experienced  in  Japan.  The   Medicines   and
Nutritionals segments comprised 49% and 20%, respectively, of the region's
sales.  Products  with  strong growth included BUFFERIN*,  TAXOL*,  HERBAL
ESSENCES*  and PARAPLATIN*. TAXOL* sales improved 90% over the prior  year
following  the  Japanese Ministry of Health and Welfare clearance  of  new
indications for TAXOL* as a treatment for breast and non-small  cell  lung
cancers.  In  1999,  margin on earnings before  taxes  increased  to  4.9%
primarily due to a decrease, as a percentage of sales, in advertising  and
promotion  spending.  As  a result of economic downturns  and  unfavorable
fluctuations  in  exchange rates, earnings before  taxes  in  the  Pacific
region  were minimal in 1998 and sales, net of inter-area sales, decreased
11%. Excluding foreign exchange, sales in 1998 increased 5% as a result of
increases  in  TAXOL* and HERBAL ESSENCES*, partly offset by decreases  in
infant formulas and CAPOTEN*.

                                        27
<PAGE>

Financial Instruments

Cash and cash equivalents, time deposits and marketable securities totaled
almost  $3.0  billion at December 31, 1999, compared to $2.5  billion  and
$1.8  billion at December 31, 1998 and 1997, respectively. Working capital
continued  to  improve  in 1999 with $3.7 billion at  December  31,  1999,
compared  to $3.0 billion and $2.7 billion at December 31, 1998 and  1997,
respectively.  Cash  and  cash equivalents, time deposits  and  marketable
securities, and the conversion of other working capital items are expected
to fund near-term operations of the Company.

The  Company is exposed to market risk due to changes in currency exchange
rates.  To  reduce  this risk, the Company enters into certain  derivative
financial instruments, where available on a cost-effective basis, to hedge
its underlying economic exposure. These instruments also are managed on  a
consolidated basis to efficiently net exposures and thus take advantage of
any natural offsets.

It  is the Company's policy to hedge certain underlying economic exposures
to  reduce foreign exchange risk. Derivative financial instruments are not
used  for  trading purposes. Gains and losses on hedging transactions  are
offset by gains and losses on the underlying exposures being hedged.

Foreign  exchange  option  contracts and,  to  a  lesser  extent,  forward
contracts  are  used  to  hedge  anticipated transactions.  The  Company's
primary foreign currency exposures in relation to the U.S. dollar are  the
European currencies and the Japanese yen.

The  table  below  summarizes the Company's outstanding  foreign  exchange
option  contracts  as  of  December 31, 1999. The  fair  value  of  option
contracts,  which  will change over time, is estimated based  on  currency
rates  and  other  relevant  market factors.  The  fair  value  of  option
contracts should be viewed in relation to the fair value of the underlying
hedged  transactions  and the overall reduction in   exposure  to  adverse
fluctuations in foreign currency exchange rates.

                        Weighted
                         Average
Dollars in Millions      Strike    Notional  Carrying   Fair
                          Price    Amount     Value     Value  Maturity
Option Contracts
Purchased
Right to Sell:
  Euro                  1.07          $971      $10      $56   2000
  Mexican Peso          11.16          212        6        -   2000
  Canadian Dollar       1.48           111        1        -   2000
  British Pound         1.64            66        1        2   2000
  Brazilian Real        1.94            63        5        2   2000
  Australian Dollar     0.65            53        1        1   2000
  Greek Drachma         316.26          40        1        2   2000
  Swiss Franc           1.48            28        -        2   2000
  Other Currencies      Various         77        3        4   2000
Right to buy:
  Japanese Yen          114.49         123        -       19   2000
  British Pound         1.61            18        -        1   2000
                                     -----     ----     ----
                                     $1762      $28      $89
                                     =====     ====     ====

                                        28
<PAGE>

At December 31, 1998, the Company held right-to-sell option contracts with
an aggregate notional amount, carrying value and fair value of $1,042
million, $22 million and $18 million, respectively. These contracts
primarily related to option contracts with the right to sell French francs
and Deutsche marks. Other contracts at December 31, 1998 included right-to-
buy option contracts, primarily to buy Japanese yen for U.S. dollars and
British pounds for Deutsche marks, as well as other option contracts, that
include the right to buy and sell several currencies. These contracts had
an aggregate notional amount, carrying value and fair value of $265
million, $5 million and $13 million, respectively.

The  Company  maintains  cash  and  cash equivalents,  time  deposits  and
marketable securities with various financial institutions. These financial
institutions are located primarily in the U.S. and Europe. Company  policy
is designed to limit exposure to any one financial institution.

Recently Issued Accounting Standards

In June 1999, the Financial Accounting Standards Board issued Statement of
Financial   Accounting  Standards  No.  137,  Accounting  for   Derivative
Instruments  and  Hedging Activities - Deferral of the effective  date  of
FASB  Statement No. 133. This statement defers the effective date of  SFAS
133,  Accounting  for  Derivative Instruments and Hedging  Activities,  to
fiscal  years beginning after June 15, 2000. This statement requires  that
companies recognize all derivatives as either assets or liabilities on the
balance  sheet  and measure these instruments at fair value.  The  Company
will  adopt  this statement on January 1, 2001 and is currently evaluating
its  impact  on  the Company's existing accounting policies and  financial
reporting disclosures.

Euro Conversion

On  January  1,  1999, certain members of the European  Union  established
fixed conversion rates between their
existing currencies and the European Union's common currency, known as the
euro. It is planned that by July 1, 2002, the participating countries will
withdraw all currencies and exclusively use the euro.

The  Company  has committed resources to conduct assessments and  to  take
corrective  actions to ensure it is prepared for the introduction  of  the
euro. The Company is actively addressing the many areas involved with  the
introduction of the euro, including information management, finance, legal
and  tax.  This review includes the conversion of information  technology,
business and financial systems, evaluating currency risk and the effect on
the  Company's financial instruments, as well as the impact on the pricing
and distribution of Company products.

The  Company believes the effect of the introduction of the euro, as  well
as  any related cost of conversion, will not have a material impact on the
results of operations, financial condition and cash flows.

Financial Position

Cash  and  cash  equivalents, time deposits and marketable  securities  at
December  31,  1999 were denominated primarily in U.S. dollar  instruments
with  near-term maturities. The average interest yield on  cash  and  cash
equivalents was 5.9% at December 31, 1999, while interest yields  on  time
deposits and marketable securities averaged 4.8% at December 31, 1999.

Short-term  borrowings  and  long-term  debt  at  December  31,  1999  are
denominated  primarily  in U.S. dollars; however,  the  Company  had  $177
million of commercial paper outstanding at December 31, 1999. This

                                        29
<PAGE>

commercial  paper has original maturities not exceeding 270  days  and  is
denominated in Euros and U.S. dollars. Also included is Japanese yen long-
term debt of $280 million.

Internally generated cash provided by operations was $4.5 billion in 1999,
$4.1 billion in 1998 and $2.5 billion in 1997. Cash provided by operations
continued to be the Company's primary source of funds to finance operating
needs  and  expenditures  for new plants and equipment.  As  part  of  the
Company's  ongoing  commitment to improve plant  efficiency  and  maintain
superior  research facilities, the Company has invested  $2.3  billion  in
capital  expansion  over the past three years. Cash flow  from  operations
also  included  product  liability payments, net of insurance  recoverable
receipts of $667 million in 1999, $519 million in 1998 and $561 million in
1997.

Cash provided by operations also was used over the past three years to pay
dividends of $4.8 billion, to finance $4.1 billion of the Company's  share
repurchase  program and to fund business acquisitions at a  cost  of  $613
million. The Company's share repurchase program authorizes the Company  to
purchase  common  stock from time to time in the open  market  or  through
private transactions as market conditions permit. During 1999, the Company
purchased  22.3 million shares of common stock at a cost of $1.4  billion,
bringing the total shares acquired since the program's inception to  299.6
million. In December 1999, the Company announced a $2 billion increase  in
the  stock repurchase program authorization. During the past three  years,
the Company has repurchased 86.5 million shares at a cost of $4.1 billion.
In  May  1999,  at  the annual meeting of stockholders,  the  stockholders
approved  the increase in the number of shares of common stock  authorized
to 4.5 billion shares.

Employment levels of 54,500 at December 1999 essentially remained at prior
year  levels  of 54,700. Sales per employee improved to $371  thousand  in
1999 from $335 thousand in 1998 and $310 thousand in 1997.

Return on Stockholders' Equity improved over the last three years and  was
51.4%  in 1999, 49.2% in 1998, excluding the special charge, and 46.5%  in
1997.

Forward Looking Information

Certain  statements in this Form 10-K Annual Report may constitute forward
looking statements within the meaning of the Private Securities Litigation
Reform   Act  of  1995.  These  statements  involve  a  number  of  risks,
uncertainties and other factors that could cause actual results to  differ
materially from expected and historical results. Certain factors that  may
affect the Company's operations and prospects are discussed in Exhibit  99
to this Form 10-K Annual Report.


                                        30
<PAGE>

Item 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA.

                       BRISTOL-MYERS SQUIBB COMPANY
      CONSOLIDATED STATEMENT OF EARNINGS and COMPREHENSIVE INCOME
                 (in millions, except per share amounts)

                                                   Year Ended December 31,
                                                  --------------------------

EARNINGS                                             1999      1998     1997
- ---------------                                   -------   -------   ------

Net Sales                                         $20,222   $18,284  $16,701
                                                   ------   -------   ------

Expenses:
Cost of products sold                               5,539     4,856   4,464
Marketing, selling, administrative and other        4,578     4,418   4,173
Advertising and product promotion                   2,409     2,312   2,241
Research and development                            1,843     1,577   1,385
Special Charge                                          -       800       -
Provision for restructuring                             -       201     225
Gain on sale of businesses                              -      (201)   (225)
Other                                                  86        53     (44)
                                                   ------   -------   -----
                                                   14,455   14,016   12,219
                                                   ------   -------   -----

Earnings Before Income Taxes                        5,767    4,268    4,482

Provision for income taxes                          1,600     1,127   1,277
                                                   ------   -------   -----

Net Earnings                                       $4,167    $3,141  $3,205
                                                    =====     =====   =====

Earnings Per Common Share
Basic                                               $2.10    $1.58    $1.61
Diluted                                             $2.06    $1.55    $1.57

Average Common Shares Outstanding
      Basic                                         1,984    1,987    1,992
      Diluted                                       2,027    2,031    2,042

Dividends Per Common Share                           $.86     $.78     $.76

COMPREHENSIVE INCOME
- --------------------
Net Earnings                                       $4,167    $3,141  $3,205

Other Comprehensive Income:
Foreign currency translation                        (212)       (86)   (195)
Tax effect                                            18         (3)     23
                                                   ------   -------   -----

Total Other Comprehensive Income                    (194)       (89)   (172)
                                                  -------   -------  ------

Comprehensive Income                              $3,973     $3,052  $3,033
                                                   =====      =====   =====

The accompanying notes are an integral part of these financial statements.

                                        31
<PAGE>

                        BRISTOL-MYERS SQUIBB COMPANY
                CONSOLIDATED STATEMENT OF RETAINED EARNINGS
                               (in millions)


                                                   Year Ended December 31,
                                                  --------------------------
                                                     1999      1998     1997
                                                   ------    ------   ------


 Retained Earnings, January 1                     $12,540   $10,950   $9,260


 Net earnings                                       4,167     3,141    3,205

                                                   ------    ------   ------
                                                   16,707    14,091   12,465
 Less dividends                                     1,707     1,551    1,515
                                                  -------   -------  -------

Retained Earnings, December 31                    $15,000   $12,540  $10,950
                                                   ======    ======   ======



The accompanying notes are an integral part of these financial statements.

                                        32
<PAGE>

                        BRISTOL-MYERS SQUIBB COMPANY
                         CONSOLIDATED BALANCE SHEET
                                   ASSETS
                           (dollars in millions)


                                                   December 31,
                                             -------------------------

                                                1999     1998     1997
                                               -----    -----    -----

Current Assets:
Cash and cash equivalents                     $2,720   $2,244   $1,456
Time deposits and marketable securities          237      285      338
Receivables, net of allowances                 3,272    3,190    2,973
Inventories                                    2,126    1,873    1,799
Prepaid expenses                                 912    1,190    1,170
                                             -------  -------  -------

  Total Current Assets                         9,267    8,782    7,736
                                             -------  -------  -------

Property, Plant and Equipment, net             4,621    4,429    4,156

Insurance Recoverable                            468      523      619
Excess of cost over net tangible assets
  received in business acquisitions            1,502    1,587    1,625

Other Assets                                   1,256      951      841
                                             -------  -------  -------

Total Assets                                 $17,114  $16,272  $14,977
                                               =====    =====    =====


















The accompanying notes are an integral part of these financial statements.

                                        33
<PAGE>

                        BRISTOL-MYERS SQUIBB COMPANY
                         CONSOLIDATED BALANCE SHEET
                    LIABILITIES AND STOCKHOLDERS' EQUITY
                           (dollars in millions)


                                                   December 31,
                                             -------------------------

                                                1999     1998     1997
LIABILITIES                                  -------  -------  -------
- -----------
Current Liabilities:
Short-term borrowings                           $432     $482     $543
Accounts payable                               1,657    1,380    1,017
Accrued expenses                               2,367    2,302    1,939
Product liability                                287      877      865
U.S. and foreign income taxes payable            794      750      668
                                             -------   ------  -------

        Total Current Liabilities              5,537    5,791    5,032

Other Liabilities                              1,590    1,541    1,447
Long-Term Debt                                 1,342    1,364    1,279
                                             -------   ------  -------

  Total Liabilities                            8,469    8,696    7,758
                                             -------   ------  -------

STOCKHOLDERS' EQUITY
- --------------------
Preferred stock, $2 convertible series:
     Authorized  10 million shares;  issued
     and outstanding 10,977 in 1999, 11,684
     in    1998   and   12,936   in   1997,       -        -        -
     liquidation value of $50 per share
Common stock, par value of $.10 per share:
     Authorized 4.5 billion shares;  issued
     2,192,970,504  in 1999,  2,188,316,808      219      219      108
     in 1998 and 1,083,253,703 in 1997
Capital in excess of par value of stock        1,533    1,075      544
Other Comprehensive Income                      (816)   (622)    (533)
Retained earnings                             15,000   12,540   10,950
                                             -------   ------  -------

                                              15,936   13,212   11,069
Less  cost  of treasury stock - 212,164,851
common shares in 1999, 199,550,532 in  1998    7,291    5,636    3,850
and 90,069,383 in 1997
                                             -------   ------  -------

Total Stockholders' Equity                     8,645    7,576    7,219
                                             -------   ------  -------

Total Liabilities and Stockholders' Equity   $17,114  $16,272  $14,977
                                              ======   ======   ======



The accompanying notes are an integral part of these financial statements.

                                        34
<PAGE>

                        BRISTOL-MYERS SQUIBB COMPANY
                    CONSOLIDATED STATEMENT OF CASH FLOWS
                           (dollars in millions)

                                                  Year Ended December
                                                          31,
                                               --------------------------
                                                 1999     1998     1997
                                               -------  -------  -------

Cash Flows From Operating Activities:
Net earnings                                    $4,167   $3,141   $3,205
Depreciation and amortization                      678      625      591
Special Charge                                       -      800        -
Provision for restructuring                          -      201      225
Gain on sale of businesses                           -     (201)    (225)
Other operating items                              (79)     (1)       33
Receivables                                       (176)    (253)    (479)
Inventories                                       (317)    (139)    (288)
Accounts payable and accrued expenses              243      242     (179)
Income taxes                                       738      414      318
Product liability                                 (726)    (715)    (795)
Insurance recoverable                               59      196      234
Other assets and liabilities                      (117)    (190)    (164)
                                               -------- -------- -------

   Net Cash Provided by Operating Activities     4,470    4,120    2,476
                                               -------  -------  -------

Cash Flows From Investing Activities:
Proceeds  from  sales of  time  deposits  and       51      309      530
marketable securities
Purchases  of  time deposits  and  marketable       (4)    (256)    (363)
securities
Additions to fixed assets                         (709)    (788)    (767)
Proceeds from sale of business                     134      417      370
Acquisition of businesses                         (266)     (93)    (254)
Other, net                                          35       65      (48)
                                               -------  -------  --------

   Net Cash Used in Investing Activities          (759)    (346)    (532)
                                               -------- -------- --------
Cash Flows From Financing Activities:
Short-term borrowings                              (26)     (81)      81
Long-term debt                                     (54)      73      328
Issuances of common stock under stock plans          8      140      117
Purchases of treasury stock                     (1,419)  (1,561)  (1,162)
Dividends paid                                  (1,707)  (1,551)  (1,515)
                                               -------- -------- --------

   Net Cash Used in Financing Activities        (3,198)  (2,980)  (2,151)
                                               -------- -------  -------

Effect of Exchange Rates on Cash                   (37)      (6)     (18)
                                               -------  -------  -------

Increase (Decrease) in Cash and Cash               476      788     (225)
Equivalents
Cash  and  Cash Equivalents at  Beginning  of    2,244    1,456    1,681
Period                                         -------  -------  -------

Cash and Cash Equivalents at End of Period      $2,720   $2,244   $1,456
                                                 =====    =====    =====

The accompanying notes are an integral part of these financial statements.

                                        35
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                        (dollars in millions)

Note 1  ACCOUNTING POLICIES
- ---------------------------

Basis  of Consolidation - The consolidated financial statements  include
the   accounts  of  Bristol-Myers  Squibb  Company  and   all   of   its
subsidiaries.

Cash  and Cash Equivalents - Cash and cash equivalents primarily include
securities  with  a  maturity of three months or less  at  the  time  of
purchase, recorded at cost, which approximates market.

Time  Deposits and Marketable Securities - Time deposits and  marketable
securities are available for sale and are recorded at fair value,  which
approximates cost.

Inventory Valuation - Inventories are generally stated at average  cost,
not in excess of market.

Capital  Assets and Depreciation - Expenditures for additions,  renewals
and  betterments  are  capitalized at cost.  Depreciation  is  generally
computed by the straight-line method based on the estimated useful lives
of  the  related assets. The estimated useful lives of the major classes
of  depreciable assets are 50 years for buildings and 3 to 40 years  for
machinery, equipment and fixtures.

Excess  of Cost over Net Tangible Assets - The excess of cost  over  net
tangible assets received in business acquisitions is being amortized  on
a straight-line basis over periods not exceeding 40 years. The excess of
cost  over  net tangible assets is periodically reviewed for  impairment
based  on  an assessment of future operations (including cash flows)  to
ensure that the excess of cost over net tangible assets is appropriately
valued.

Product Liability - Accruals for product liability are recorded,  on
an undiscounted basis, when it is probable that a liability has been
incurred   and  the  amount  of  the  liability  can  be  reasonably
estimated,  based  on  existing  information.  These  accruals   are
adjusted   periodically  as  assessment  efforts  progress   or   as
additional  information becomes available. Receivables  for  related
insurance  or  other third party recoveries for product  liabilities
are  recorded, on an undiscounted basis, when it is probable that  a
recovery  will  be realized. Insurance recoverable recorded  on  the
balance sheet has, in general, payment terms of three years or less.

Revenue Recognition - Revenue from product sales is recognized upon
shipment to customers.

Earnings  Per  Share  -  Basic earnings  per  common  share  are
computed using the weighted average number of shares outstanding
during the year.  Diluted earnings per common share are computed
using  the weighted average number of shares outstanding  during
the  year, plus the incremental shares outstanding assuming  the
exercise of dilutive stock options


                                        36
<PAGE>


                      BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)


Note 2  ACQUISITIONS AND DIVESTITURES
- -------------------------------------

In  June  1999,  the Company acquired Cal-C-Tose, a nutritional  milk
modifier.  In September 1999, the Company entered into a  development
and  commercialization agreement for aripiprazole, a novel drug under
study  in  Phase  III  trials as a treatment for schizophrenia,  with
Otsuka   Pharmaceutical  Co.,  Ltd.  In  December  1999  the  Company
completed  the  sale of Laboratori Guieu, a gynecological,  pediatric
and  dermatological products business headquartered in  Milan  Italy.
The gain on the sale was not material.

In  1998 the Company acquired Redmond Products, Inc., a leading  hair
care  manufacturer in the United States, and Phytoervas,  a  line  of
premium retail shampoos and conditioners in Brazil.  The Company also
in 1998 acquired Dong-A-Biotech Co., Ltd., a marketer and distributor
of  pharmaceutical  products in South Korea.  In  1998,  the  Company
divested its Ban brand of anti-perspirants and deodorants, A/S GEA, a
Denmark-based  generic  drug business, and  Hexachimie,  a  specialty
chemical manufacturer based in France, resulting in a combined pretax
gain of $201 million.

In  1997, the Company completed the sale of Linvatec Corporation, its
arthroscopy and surgical powered instrument business, resulting in  a
pretax  gain  of  $225  million.  The Company acquired  Abeefe  S.A.,
Peru's  largest pharmaceutical manufacturer and marketer of  a  broad
range    of    prescription   and   nonprescription   anti-infective,
respiratory,  anti-inflammatory  and  dermatological  products.   The
Company  also  acquired  CHOCO  MILK*,  Mexico's  leading  milk-based
nutritional   supplement,  and  SAL  DE  UVAS   PICOT*,   a   leading
effervescent antacid product in Mexico.


Note 3  EARNINGS PER SHARE
- --------------------------

The computations for basic earnings per common share and diluted
earnings per common share are as follows:

Earnings per Common Share  - Basic:
- -----------------------------------
                                                      Year Ended
                                                      December 31,
                                                     -------------

Dollars in Millions (Except per Share             1999     1998     1997
Amounts)                                        ------   ------   ------
- -------------------------------------

Net Earnings                                    $4,167   $3,141   $3,205
                                                  ====     ====     ====

Average Common Shares Outstanding                1,984    1,987    1,992
                                                  ====     ====     ====

Earnings Per Common Share - Basic                $2.10    $1.58    $1.61
                                                  ====     ====     ====

                                        37
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                             (dollars in millions)


Earnings per Common Share - Diluted:
- ------------------------------------
                                              Year Ended December 31,
                                             -------------------------

Dollars in Millions (Except per Share            1999     1998     1997
Amounts)                                       ------   ------   ------
- -------------------------------------

Net Earnings                                   $4,167   $3,141   $3,205
                                                 ====     ====     ====

Average Common Shares Outstanding               1,984    1,987    1,992
Incremental Shares Outstanding Assuming the
Exercise of Dilutive Stock Options                 43       44       50
                                                -----    -----    -----

Average Common Shares Outstanding               2,027    2,031    2,042
                                                =====    =====    =====

Earnings Per Common Share - Diluted             $2.06    $1.55    $1.57
                                                =====    =====    =====


Note 4  OTHER INCOME AND EXPENSES
- ---------------------------------

                                                 Year Ended December 31,
                                               ---------------------------
                                                1999       1998      1997
                                              ------     ------    ------
Interest income                                 $107        $87      $106
Interest expense                                (130)      (154)     (118)
Other - net                                      (63)        14        56
                                               -----      -----     -----
                                                $(86)      $(53)      $44
                                                ====       ====      ====


Cash  payments  for  interest were $119 million, $157  million  and  $110
million in 1999, 1998 and 1997, respectively.



                                        38
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)


Note 5  PROVISION FOR INCOME TAXES
- ----------------------------------

The components of earnings before income taxes were:

                                                     December 31,
                                              ---------------------------
                                                1999       1998      1997
                                               -----      -----     -----
U.S.                                          $3,644     $2,623    $2,858
Non-U.S.                                       2,123      1,645     1,624
                                               -----     ------    ------
                                              $5,767     $4,268    $4,482
                                               =====      =====     =====

The provision for income taxes consisted of:

                                                     December 31,
                                              ---------------------------
                                                1999       1998      1997
                                               -----      -----     -----
Current:
U.S.                                            $780       $827      $633
Non-U.S.                                         405        346       471
                                               -----      -----     -----
                                               1,185      1,173     1,104
                                               =====      =====     =====

The components of prepaid and deferred income taxes consisted of:

                                                     December 31,
                                              ---------------------------
                                                1999       1998      1997
                                               -----      -----     -----
Deferred:
U.S.                                             365        (64)      220
Non-U.S.                                          50         18       (47)
                                               -----     ------     -----
                                                 415        (46)      173
                                               -----     ------     -----
                                              $1,600     $1,127    $1,277
                                               =====      =====     =====

                                        39
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)


Income  taxes paid during the year were $805 million, $654 million  and
$898 million in 1999, 1998 and 1997, respectively.

The  Company's provision for income taxes in 1999, 1998  and  1997  was
different  from  the amount computed by applying the  statutory  United
States  Federal income tax rate to earnings before income taxes,  as  a
result of the following:

                                                   % of Earnings
                                                Before Income Taxes
                                                ----------------------
                                               1999      1998     1997
                                              -----     -----    -----
U.S. statutory rate                           35.0%     35.0%    35.0%
Foreign                                       (5.0)     (4.4)    (2.6)
Effect of operations in Puerto Rico           (1.8)     (2.5)    (2.9)
Special charge                                   -       (.6)       -
State and local taxes                           .6        .6       .6
Other                                         (1.1)     (1.7)    (1.6)
                                              -----     -----    -----
                                              27.7%     26.4%    28.5%
                                              =====     =====    =====


Prepaid taxes at December 31, 1999, 1998 and 1997 were $567 million, $809
million   and  $818  million,  respectively.  The  deferred  income   tax
liability, included in Other Liabilities, at December 31, 1999, 1998  and
1997 was $445 million, $277 million and $352 million, respectively.

The components of prepaid and deferred income taxes consisted of:

                                                   December 31,
                                               ----------------------
                                               1999      1998     1997
                                              -----     -----    -----
Depreciation                                 $(278)    $(278)   $(278)
Postretirement and pension benefits            120       195      191
Product liability                              (13)      248      154
Restructuring                                   25        55       77
Other                                          268       312      322
                                              -----     -----    -----
                                              $122      $532     $466
                                              ====      ====     ====

                                        40
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                         (dollars in millions)


The  Company has settled its United States Federal income tax returns
with the Internal Revenue Service through 1991.

United  States  Federal  income  taxes  have  not  been  provided  on
substantially   all   of   the  unremitted   earnings   of   non-U.S.
subsidiaries,  since  it  is  management's  practice  and  intent  to
reinvest  such earnings in the operations of these subsidiaries.  The
total  amount of the net unremitted earnings of non-U.S. subsidiaries
was approximately $4.4 billion at December 31, 1999.


Note 6  INVENTORIES
- -------------------
                                                   December 31,
                                               ----------------------
                                               1999      1998     1997
                                             ------    ------   ------
Finished goods                               $1,472    $1,209   $1,153
Work in process                                 302       236      197
Raw and packaging materials                     352       428      449
                                              -----     -----    -----
                                             $2,126    $1,873   $1,799
                                              =====     =====    =====


Note 7  PROPERTY, PLANT AND EQUIPMENT
- -------------------------------------

                                                   December 31,
                                               ----------------------
                                               1999      1998     1997
                                              -----     -----    -----
Land                                           $170      $176     $180
Buildings                                     3,096     2,875    2,631
Machinery, equipment and fixtures             4,093     3,885    3,646
Construction in progress                        482       572      544
                                              -----     -----    -----
                                              7,841     7,508    7,001
Less accumulated depreciation                 3,220     3,079    2,845
                                              -----     -----    -----
                                             $4,621    $4,429   $4,156
                                              =====     =====    =====

                                        41
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                         (dollars in millions)


Note 8  SHORT-TERM BORROWINGS AND LONG-TERM DEBT
- ------------------------------------------------

Included  in  short-term  borrowings  were  amounts  due  to   banks,
primarily  foreign  banks, of $245 million,  $272  million  and  $524
million  at  December  31,  1999, 1998 and  1997,  respectively,  and
current  installments of long-term debt of $10 million,  $43  million
and  $19  million at December 31, 1999, 1998, and 1997, respectively.
Also included in short-term borrowings at December 31, 1999 and 1998,
was  $177 million and $167 million, respectively, of commercial paper
outstanding.  This  commercial  paper  has  original  maturities  not
exceeding 270 days and is denominated in euros and U.S. dollars.  The
average  interest  rate on short-term borrowings  was  6.76%  and  on
current  installments  of long-term debt was 6.81%  at  December  31,
1999.

During  1999, the Company renewed two credit facilities,  aggregating
$500  million,  with  a  syndicate of  lenders  as  support  for  its
commercial  paper program. The credit facilities consist  of  a  $250
million, 364-day credit facility, which may be renewed annually  with
the  consent  of the lenders for an additional 364-day period  and  a
$250 million, four- and five-year credit facility, extendible at each
anniversary  date  with the consent of the lenders.   There  were  no
borrowings  outstanding under the credit facilities at  December  31,
1999.  In addition, the Company has unused short-term lines of credit
with foreign banks of $420 million.


The components of long-term debt were:
                                                   December 31,
                                               ----------------------
                                               1999      1998     1997
                                              -----     -----    -----
6.80% Debentures, due in 2026                  $345      $345     $344
7.15% Debentures, due in 2023                   344       344      343
6.875% Debentures, due in 2097                  296       296      296
Various Rate Yen Term Loans, due in 2003         71        71       70
2.14% Yen Notes, due in 2005                     62        55        -
1.73% Yen Notes, due in 2003                     62        54        -
3.51% Deutsche Mark Interest on Yen
Principal Term Loan, due in 2005                 57        50       49
5.75% Industrial Revenue Bonds, due in 2024      34        34       34
5.00% Yen Term Loan, paid in 1999                 -        29       29
Various Rate Term Loans, paid in 1999             -         -       26
2.83% Yen Term Loan, due in 2002                 28        25       24
Capitalized Leases                               22        29       26
Other, 4.30% to 10.25%,due in varying
  amounts through 2014                           21        32       38
                                             ------   -------  -------
                                             $1,342    $1,364   $1,279
                                              =====     =====    =====

                                        42
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                        (dollars in millions)


Note 9  STOCKHOLDERS' EQUITY
- ----------------------------

Changes  in capital shares and capital in excess of par value  of  stock
were:


                                    Shares of Common Stock      Capital in
                                   -----------------------      Excess of
                                                                Par Value
                                                                of Stock
                                                                (dollars in
                                                                millions)

                                        Issued      Treasury
                                      ----------   -----------      ------

Balance, December 31, 1996         1,082,496,016    81,806,550        $382
Issued pursuant to stock plans
and options                              738,151    (8,514,867)        162
Conversions of preferred stock            19,536             -           -
Purchases                                      -    16,777,700           -
                                      ----------   -----------      ------

Balance, December 31, 1997         1,083,253,703    90,069,383         544
Effect of two-for-one stock split  1,083,253,703    90,069,383        (108)
Issued  pursuant to  stock  plans
and options                           16,931,302   (11,189,998)        700
Conversions of preferred stock            21,230             -           -
Purchases                                      -    30,601,764           -
Other                                  4,856,870             -         (61)
                                      ----------   -----------      ------

Balance, December 31, 1998         2,188,316,808   199,550,532       1,075
Issued  pursuant to  stock  plans
and options                            4,641,700   (9,694,871)         458
Conversions of preferred stock            11,996            -            -
Purchases                                      -   22,309,190            -
                                      ----------   -----------      ------

Balance, December 31, 1999         2,192,970,504   212,164,851      $1,533
                                   =============   ===========      ======


Each  share of the Company's preferred stock is convertible into  16.96
shares  of  common stock and is callable at the Company's  option.  The
reductions in the number of issued shares of preferred stock  in  1999,
1998 and 1997 were due to conversions into shares of common stock.

Dividends per common share were $.86 in 1999, $.78 in 1998  and  $.76
in 1997.


                                        43
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                        (dollars in millions)

Stock Compensation Plans
- ------------------------

Under the Company's 1997 Stock Incentive Plan, officers, directors  and
key  employees may be granted options to purchase the Company's  common
stock  at no less than 100% of the market price on the date the  option
is granted. Options generally become exercisable in installments of 25%
per  year on each of the first through the fourth anniversaries of  the
grant date and have a maximum term of 10 years. Additionally, the  plan
provides  for  the  granting of stock appreciation rights  whereby  the
grantee  may  surrender exercisable options and  receive  common  stock
and/or  cash measured by the excess of the market price of  the  common
stock  over the option exercise price. The plan also provides  for  the
granting of performance-based stock options to certain key executives.

Under  the  terms  of  the  1997  Stock  Incentive  Plan,  as  amended,
additional  shares  are  authorized  in  the  amount  of  0.9%  of  the
outstanding  shares  per year through 2002. The plan  incorporates  the
Company's long-term performance awards.

In addition, the 1997 Stock Incentive Plan provides for the granting of
up  to  20,000,000 shares of common stock to key employees, subject  to
restrictions as to continuous employment except in the case of death or
normal  retirement.  Restrictions generally  expire  over  a  five-year
period from date of grant. Compensation expense is recognized over  the
restricted  period.  At  December  31,  1999,  a  total  of   2,135,524
restricted shares were outstanding under the plan.

Under  the  TeamShare  Stock  Option  Plan,  all  full-time  employees,
excluding key executives, meeting certain years of service requirements
are  granted  options  to purchase the Company's common  stock  at  the
market  price  on  the date the options are granted.  The  Company  has
authorized  62,000,000  shares  for issuance  under  the  plan.  As  of
December  31,  1999, a total of 23,579,400 shares have  been  exercised
under the plan.

The  Company  applies  Accounting  Principles  Board  Opinion  No.  25,
Accounting  for  Stock Issued to Employees, and related interpretations
in  accounting for its plans. Accordingly, no compensation expense  has
been  recognized for its stock-based compensation plans other than  for
restricted  stock  and performance-based awards. Had compensation  cost
for  the Company's other stock option plans been determined based  upon
the  fair  value  at  the  grant  date for  awards  under  these  plans
consistent with the methodology prescribed under Statement of Financial
Accounting  Standards No. 123, Accounting for Stock-Based Compensation,
the Company's net income and earnings per share would have been reduced
by  approximately  $198 million, or $.10 per common  share,  basic  and
diluted,  in  1999, $136 million, or $.07 per common share,  basic  and
diluted,  in 1998 and $85 million, or $.04 per common share, basic  and
diluted,  in  1997. The fair value of the options granted during  1999,
1998  and  1997  was estimated as $17.37 per common share,  $11.80  per
common  share and $6.41 per common share, respectively, on the date  of
grant  using the Black-Scholes option-pricing model with the  following
assumptions:


                                        44
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                        (dollars in millions)


                                               1999      1998     1997
                                             ------    ------   ------
Dividend yield                                 2.4%      3.1%     4.3%
Volatility                                    21.8%     18.2%    19.3%
Risk-free interest rate                        5.5%      6.3%     6.5%
Assumed forfeiture rate                        3.0%      3.0%     3.0%
Expected life (years)                           7        7        7



Stock option transactions were:
                                                              Weighted
                                                              Average
                                    Shares of Common Stock    Exercise
                                   -----------------------    Price of
                                                              Shares
                                                             Under Plan
                                    Available      Under
                                   for Option      Plan
                                   ----------   -----------      ------

Balance, December 31, 1996         18,329,358    70,028,732      $34.27
Authorized                          9,006,205             -           -
Granted                           (11,347,801)   11,347,801       65.77
Exercised                                   -   (12,787,811)      30.34
Lapsed                              2,284,788    (2,287,820)      45.63
                                   ----------   -----------

Balance, December 31, 1997         18,272,550    66,300,902       40.08
Effect of two-for-one stock split  18,272,550    66,300,902           -
Authorized                         17,877,318             -           -
Granted                           (35,498,350)   35,498,350       51.40
Exercised                                   -   (36,697,942)      16.30
Lapsed                              2,382,746    (2,382,746)      34.27
                                   ----------   -----------

Balance, December 31, 1998         21,306,814   129,019,466       29.47
Authorized                         19,898,896             -           -
Granted                           (24,221,950)   24,221,950       65.39
Exercised                                   -   (20,425,070)      20.41
Lapsed                              3,552,037    (3,552,037)      42.51
                                   ----------   -----------

Balance, December 31, 1999         20,535,797   129,264,309      $37.27
                                   ==========   ===========

                                        45
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)


The   following   table   summarizes  information  concerning   currently
outstanding and exercisable options:


                     Options Outstanding            Options Exercisable
            ------------------------------------- ------------------------

 Range of     Number      Weighted     Weighted     Number      Weighted
 Exercise   Outstanding    Average     Average    Exercisable    Average
  Prices                  Remaining    Exercise                 Exercise
                         Contractual    Price                     Price
                            Life
$10 - $20     36,055,360    4.10       $15.61     36,050,360     $15.61
$20 - $30     23,777,750    6.29        24.32     19,415,975      24.57
$30 - $40     12,441,697    7.19        33.68      6,530,637      33.68
$40 - $50      4,319,338    8.09        45.70        158,263      44.10
$50 - $60     29,924,664    8.18        51.73      5,012,685      51.00
$60 - up      22,745,500    9.19        66.49        152,319      61.10
             -----------                          ----------
             129,264,309                          67,320,239
             ===========                          ==========


At  December 31, 1999, 204,705,699 shares of common stock were  reserved
for  issuance  pursuant  to  stock plans,  options  and  conversions  of
preferred stock.


Note 10  FINANCIAL INSTRUMENTS
- ------------------------------

Foreign  exchange  option  contracts and, to a  lesser  extent,  forward
contracts,  are used to hedge anticipated foreign currency transactions,
primarily intercompany inventory purchases expected to occur within  the
next year.

The Company has exposures to net foreign currency denominated assets and
liabilities,  which  approximated $2,179  million,  $2,310  million  and
$2,070  million  at  December  31, 1999, 1998  and  1997,  respectively,
primarily in Europe, Japan and Canada. The Company mitigates the  effect
of these exposures through third-party borrowings.

The  risk  of loss associated with the types of foreign exchange  option
contracts entered into by the Company is limited to premium amounts paid
for  the option contracts. Premiums are deferred in Prepaid Expenses and
amortized  in  the  consolidated statement of  earnings  (in  the  Other
caption) over the time frame of the underlying hedged transaction. Gains
related  to  the  option contracts, which qualify as hedges  of  foreign
currency  anticipated transactions, are recognized in earnings when  the
hedged transactions are recognized. Gains and losses on foreign exchange
forward  contracts  are  recognized  in  the  basis  of  the  underlying
transaction being hedged.

                                        46
<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                           (dollars in millions)


The  notional amounts of the Company's foreign exchange option contracts
at  December 31, 1999, 1998 and 1997 were $1,762 million, $1,307 million
and $1,279 million, respectively.

The  Company does not anticipate any material adverse effect  on  its
financial   position   resulting  from  its  involvement   in   these
instruments,  nor does it anticipate non-performance by  any  of  its
counterparties.

At  December  31,  1999,  1998 and 1997, the carrying  value  of  all
financial instruments, both short- and long-term, approximated  their
fair values.


Note 11  LEASES
- ---------------

Minimum   rental  commitments  under  all  noncancelable  operating
leases, primarily real estate, in effect at December 31, 1999 were:

Years Ending December 31,
- -------------------------
2000                                            $109
2001                                              97
2002                                              80
2003                                              60
2004                                              46
Later years                                      141
                                              ------
Total minimum payments                           533
Less total minimum sublease rentals              111
                                              ------
Net minimum rental commitments                  $422
                                                 ===


Operating  lease rental expense (net of sublease rental  income  of
$24  million in 1999, $27 million in 1998 and $26 million in  1997)
was  $90 million in 1999, $105 million in 1998 and $124 million  in
1997.






                                        47
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                         (dollars in millions)


Note 12  SEGMENT INFORMATION
- ----------------------------

The  major  product  categories for each business  segment  are  as
follows:
                                              Year Ended December 31,
                                              ----------------------
                                              1999     1998     1997
                                             ------   ------   ------
Medicines
 PRAVACHOL*                                  $1,704    $1,643   $1.437
 TAXOL*                                       1,481     1,206      941
 GLUCOPHAGE                                   1,317       862      579
 Oncology Therapeutics Network                  894       657      480
 BUSPAR*                                        605       531      443
 ZERIT*                                         605       551      398
 PARAPLATIN*                                    600       525      437
 PLAVIX                                         547       144        -
Beauty Care
 Hair care                                    1,250     1,179      794
 Haircolor                                      905       894      841
Nutritionals
 Infant formulas                              1,233     1,203    1.219
Medical Devices
 Orthopaedic implants                           665       596      615
 Ostomy                                         449       464      451


Inter-area  sales,  which are usually billed at or above  manufacturing
costs, by geographic area, were:

                                                   December 31,
                                              ----------------------
                                               1999      1998     1997
                                             ------    ------   ------
United States                                $1,647    $1,434   $1,370
Europe, Mid-East and Africa                     937       843      762
Other Western Hemisphere                         46        29       32
Pacific                                          25        16       24
                                             ------   -------  -------
Total inter-area eliminations                $2,655    $2,322   $2,188
                                              =====     =====    =====

The  Medicines  Segment represents pharmaceuticals and  consumer  medicines
businesses. In addition, the segment information reflects certain  internal
organizational  changes  made in 1999. Prior year data  has  been  restated
accordingly.

                                        48
<PAGE>

                     BRISTOL-MYERS SQUIBB COMPANY
                 NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                           (dollars in millions)


Included  in  earnings before taxes of each segment is a  cost  of  capital
charge.  The offset to the cost of capital charge is included in Other.  In
addition, Other principally consists of interest income, interest  expense,
certain  administrative expenses and allocations to the  industry  segments
for certain corporate programs. In 1998, Other includes the gain on sale of
businesses  of  $201  million and the provision for restructuring  of  $201
million.  In  1997, Other includes the gain on sale of a business  of  $225
million  and the provision for restructuring of $225 million. Other  assets
principally  consist  of  cash  and cash  equivalents,  time  deposits  and
marketable securities, and certain other assets.

BUSINESS SEGMENTS              Net Sales            Earnings Before Taxes
- -----------------       ------------------------    ----------------------

                           1999     1998     1997    1999    1998    1997
                          -----    -----    -----   -----   -----   -----
Medicines               $14,309  $12,573  $11,211  $4,018  $3,402  $3,033
Beauty Care               2,381    2,305    1,895     247     343     269
Nutritionals              1,850    1,759    1,793     375     371     360
Medical Devices           1,682    1,647    1,802     365     336     345
                          -----    -----    -----   -----   -----   -----
Net sales and earnings
before taxes            $20,222  $18,284  $16,701  $5,005  $4,452  $4,007

                          =====    =====    =====   =====   =====   =====


GEOGRAPHIC AREAS               Net Sales          Earnings Before Taxes
- ----------------       -------------------------- -----------------------

                           1999     1998     1997    1999    1998    1997
                          -----    -----    -----   -----   -----   -----
United States           $14,445  $12,527  $11,014  $3,491  $3,164  $2,581
Europe, Mid-East and
Africa                    5,040    4,873    4,653   1,268   1,139   1,109
Other Western Hemisphere  1,681    1,749    1,586     110     223     225
Pacific                   1,711    1,457    1,636      83       2      52
Inter-area eliminations  (2,655)  (2,322)  (2,188)     53     (76)     40
                          -----     -----    -----  -----  -----   -----
Net sales and earnings
before taxes            $20,222  $18,284  $16,701   5,005   4,452   4,007
                          =====    =====    =====
Special Charge                                          -    (800)      -
Other                                                 762     616     475
                                                    -----   -----   -----
                                                   $5,767  $4,268  $4,482
                                                    =====   =====   =====

                                        49
<PAGE>

                        BRISTOL-MYERS SQUIBB COMPANY
                 NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                            (dollars in millions)


BUSINESS SEGMENTS                                 Year-End Assets
- -----------------                               ----------------------
                                               1999      1998     1997
                                             ------    ------   ------
Medicines                                    $8,769    $8,296   $7,964
Beauty Care                                   1,121     1,058      833
Nutritionals                                  1,190     1,094    1,113
Medical Devices                               1,185     1,174    1,225
                                             ------   -------  -------
Identifiable segment assets                 $12,265   $11,622  $11,135
                                             ======    ======   ======


GEOGRAPHIC AREAS                                  Year-End Assets
- ----------------                                ----------------------
                                              1999       1998     1997
                                             -----     ------   ------
United States                               $6,989     $6,657   $6,417
Europe, Mid-East and Africa                  3,622      3,533    3,426
Other Western Hemisphere                     1,425      1,238    1,063
Pacific                                        943        942      989
Inter-area eliminations                       (714)     (748)    (760)
                                            ------    -------  -------
Identifiable geographic assets             $12,265    $11,622  $11,135
Other assets                                 4,849      4,650    3,842
                                            ------    -------  -------
                                           $17,114    $16,272  $14,977
                                            ======     ======   ======


BUSINESS SEGMENTS             Capital Expenditures        Depreciation
- -----------------           --------------------------  -----------------

                              1999     1998    1997    1999    1998    1997
                               ---   ------   -----  ------   -----   -----
Medicines                     $457     $535    $524    $279    $272    $244
Beauty Care                     58       71      58      35      29      22
Nutritionals                    56       59      61      43      38      42
Medical Devices                 44       33      24      32      36      46
                               ---   ------   -----  ------   -----   -----
Business segment total         615      698     667     389     375     354
                                94       90     100      49      38      43
                               ---   ------   -----  ------   -----   -----
                              $709     $788    $767    $438    $413    $397
                               ===      ===     ===     ===     ===     ===

                                        50
<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                           (dollars in millions)

Note 13  RETIREMENT PLANS
- -------------------------

The  Company  and  certain of its subsidiaries  have  defined  benefit
pension  plans  and  defines contribution plans for regular  full-time
employees.  The  principal  pension plan is the  Bristol-Myers  Squibb
Retirement  Income Plan. The Company's funding policy is to contribute
amounts  to  provide  for current service and  to  fund  past  service
liability.  Plan  benefits are primarily based on  years  of  credited
service and on the participants' compensation. Plan assets principally
consist of equity and fixed income securities.

Cost  for  the Company's defined benefit plans included the  following
components:


                                                 Year Ended December 31,
                                                 ----------------------
                                                1999       1998     1997
                                               -----     ------   ------

Service cost - benefits earned during the year  $161       $132     $135
Interest cost on projected benefit obligation    217        207      203
obligation
Expected earnings on plan assets                (285)      (258)    (231)
Net amortization and deferral                      4         (1)      10
                                                ----       ----     ----
Net pension expense                              $97        $80     $117
                                                ====       ====     ====


The  weighted  average  actuarial assumptions for the  Company's  pension
plans were as follows:

                                                   December 31,
                                             -------------------------
                                               1999      1998     1997
                                             ------    ------   ------
Discount rate                                  7.8%      7.0%     7.5%
Compensation increase                          4.8%      4.3%     4.5%
Long-term rate of return                      10.0%     10.0%    10.0%









                                        51
<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)

Changes in benefit obligation and plan assets were:

                                                   Year Ended December 31,
                                                   ----------------------
                                                  1999      1998     1997
                                                  ----      ----     ----
Benefit obligation at beginning of year         $3,216    $2,928   $2,734
Service cost - benefits earned during the year     161       132      135
year
Interest cost on projected benefit obligation      217       207      203
Actuarial (gains) and losses                      (203)      160       45
Benefits paid                                     (254)     (211)    (189)
                                                 -----     -----    -----
Benefit obligation at end of year               $3,137    $3,216   $2,928
                                                 =====     =====    =====

                                                       December 31,
                                                    ----------------------
                                                  1999      1998     1997
                                                 -----    ------   ------
Fair value of plan assets at beginning of year  $3,137    $2,949   $2,596
Actual earnings on plan assets                     561       359      504
Employer contribution                               46        40       38
Benefits paid                                     (254)     (211)    (189)
                                                ------    ------   ------
Fair value of plan assets at end of year        $3,490    $3,137   $2,949
                                                 =====     =====    =====

                                                     December 31,
                                                   ----------------------
                                                  1999      1998     1997
                                                 -----     -----    -----
Plan assets in excess of (less than)
projected benefit obligation                      $353      $(79)     $21
Unamortized net assets at adoption                  (2)      (33)     (47)
Unrecognized prior service cost                     37        48       56
Unrecognized net (gains) and losses               (385)       87       13
                                                 -----     -----    -----
Net amount recognized                               $3       $23      $43
                                                  ====      ====     ====

Amounts recognized in the consolidated balance sheet
    consist of:
Prepaid benefit cost                               181       187      194
Accrued benefit liability                         (190)     (190)    (173)
Other asset                                         12        26       22
                                                 -----     -----    -----
Net amount recognized                               $3       $23      $43
                                                  ====      ====     ====

                                        52
<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                 NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                           (dollars in millions)


The  projected benefit obligation, accumulated benefit obligation,  and
fair  value  of  plan  assets for the pension  plans  with  accumulated
benefit  obligations in excess of plan assets were $319  million,  $245
million  and $56 million, respectively, as of December 31,  1999,  $288
million, $230 million and $40 million, respectively, as of December 31,
1998  and $271 million, $208 million and $37 million, respectively,  as
of  December  31, 1997. This is primarily attributable to  an  unfunded
benefit equalization plan.

The  principal  defined  contribution plan is the  Bristol-Myers  Squibb
Savings and Investment Program.  The Company's contribution is based  on
employee  contributions  and  the  level  of  company  match.    Company
contributions to the plan were $49 million in 1999, $45 million in  1998
and $40 million in 1997.


Note 14  POSTRETIREMENT BENEFIT PLANS OTHER THAN PENSIONS
- ---------------------------------------------------------

The  Company provides comprehensive medical and group life benefits  to
substantially  all  U.S.  retirees who  elect  to  participate  in  the
Company's comprehensive medical and group life plans. The medical  plan
is  contributory. Contributions are adjusted periodically and  vary  by
date  of  retirement  and  the  original  retiring  company.  The  life
insurance plan is non-contributory. Plan assets principally consist  of
equity securities and fixed income securities.

Cost  for  the  Company's  postretirement benefit  plans  included  the
following components:

                                              Year Ended December 31,
                                              ----------------------
                                                1999       1998     1997
                                               -----      -----    -----

Service cost - benefits earned during the year   $10         $8       $9
Interest cost on accumulated postretirement       36         35       36
benefit obligation
Expected earnings on plan assets                 (13)       (11)      (9)
Net amortization and deferral                      1         (3)      (2)
                                               -----      -----    -----
Net postretirement benefit expense               $34        $29      $34
                                                ====       ====     ====

                                        53
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
                 NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                           (dollars in millions)


The   weighted   average  actuarial  assumptions  for   the   Company's
postretirement benefit plans were as follows:

                                                   December 31,
                                              ----------------------
                                               1999      1998     1997
                                             ------    ------   ------
Discount rate                                  7.8%      7.0%     7.5%
Long-term rate of return                      10.0%     10.0%    10.0%


Changes in benefit obligation and plan assets were:

                                              Year Ended December 31,
                                              -----------------------
                                              1999       1998     1997
                                             -----      -----    -----
Benefit obligation at beginning of year       $507       $495     $482
Service cost - benefits earned during the
year                                            10          8        9
Interest cost on accumulated post-
retirement benefit obligation                   36         35       36
Plan participants' contributions                 2          2        2
Plan amendments                                 (9)        (1)       -
Actuarial (gains) and losses                    16          6       (2)
Benefits paid                                  (41)       (38)     (32)
                                             -----      -----    -----
Benefit obligation at end of year             $521       $507     $495
                                              ====       ====     ====

                                                   December 31,
                                              ----------------------
                                              1999       1998     1997
                                             -----     ------   ------
Fair value of plan assets at beginning of
year                                          $128       $113      $89
Actual earnings on plan assets                  24         15       20
Employer contribution                           39         36       34
Plan participants' contributions                 2          2        2
Benefits paid                                  (41)       (38)     (32)
                                             -----      -----   ------
Fair value of plan assets at end of year      $152       $128     $113
                                              ====       ====     ====



                                        54
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
              NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                        (dollars in millions)


                                                   December 31,
                                              ----------------------
                                               1999      1998     1997
                                             ------    ------   ------
Accumulated postretirement benefit
obligation in excess of plan assets           $(369)    $(379)   $(382)
Unrecognized prior service cost                  (6)        3        4
Unrecognized net earnings                       (55)      (60)     (65)
                                              -----     -----    -----
Accrued postretirement benefit expense        $(430)    $(436)   $(443)
                                               ====      ====     ====

For  measurement purposes, an annual rate of increase in the  per  capita
cost  of  covered health care benefits of 7% for participants was assumed
for 2000; the rate was assumed to decrease gradually to 5% in 2007 and to
remain at that level thereafter.

A  one-percentage-point change in assumed health care cost trend  rates
would have the following effects:

                                            1-Percentage-  1-Percentage-
                                                Point          Point
                                              Increase       Decrease

                                             ----------   ------------

Effect on the aggregate of the service and
interest cost components of net postretirement
benefit expense                                  $1            $(1)
Effect on the accumulated postretirement
benefit obligation                              $21           $(19)


Note 15  LITIGATION
- -------------------

Various lawsuits, claims and proceedings of a nature considered normal to
its businesses are pending against
the  Company  and  certain of its subsidiaries. The most  significant  of
these  are described below. Reference is made to Item 3 Legal Proceedings
in Part 1 of this Form 10-K Annual Report.

Breast Implant
- --------------

The   Company,   together  with  its  subsidiary,   Medical   Engineering
Corporation  (MEC),  and certain other companies, has  been  named  as  a
defendant  in  a  number  of  claims and lawsuits  alleging  damages  for
personal  injuries  of  various types resulting from polyurethane-covered
breast  implants and smooth-walled breast implants formerly  manufactured
by  MEC or a related Company. Of the more than 90,000 claims or potential
claims against the Company in direct lawsuits or through registration  in
the  nationwide class action settlement approved by the Federal  District
Court  in Birmingham, Alabama (the "Revised Settlement"), most have  been
dealt with through the  Revised Settlement, other settlements,  or trial.


                                        55
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)

As of December  31, 1999, the Company's contingent liability in  respect
of  breast  implant claims was limited  to  residual  unpaid Revised
Settlement  obligations and to roughly 1,700 remaining  opt-outs who have
pursued or may pursue their claims in court.

As  of  December  31,  1999, approximately 6,700 United  States  and  200
foreign breast implant recipients were plaintiffs in lawsuits pending  in
federal  and  state  courts in the United States and  certain  courts  in
Canada and Australia. These figures include the claims of plaintiffs that
are in the process of being settled and/or dismissed.In  these lawsuits,
about 3,660 U.S. and 49 foreign plaintiffs opted  out of the Revised
Settlement. The lawsuits of  the  3,040  U.S. plaintiffs who did not opt
out are  expected  to  be dismissed  since  these plaintiffs are among the
estimated  74,000  women with  MEC implants who chose to participate in the
nationwide settlement. Of  the  3,660  opt-out plaintiffs, an estimated
1,960 have claims  based upon products that were not manufactured or sold
by MEC or that have been or are in the process of being settled and/or
dismissed. Accordingly, the number  of  remaining  plaintiffs who have
pursued or  may  pursue  their claims  in court against the Company is
roughly 1,700, as stated  in  the preceding paragraph.

Under  the  terms  of  the  Revised Settlement, additional  opt-outs  are
expected to be minimal since the deadline for  U.S. class members to opt
out has passed. In addition, the Company's remaining  obligations under
the Revised Settlement Program  are  limited because  most payments to
"Current Claimants" have already been made, no additional  "Current  Claims"
may be filed without  court  approval,  and because  payments  of claims
to so-called "Other Registrants"  and  "Late Registrants" are limited by
the terms of the Revised Settlement. Separate class  action settlements
have been approved in the provincial courts  of Ontario  and Quebec, and
an agreement has been reached under which  other foreign  breast implant
recipients may settle their claims.  The  Company believes it will be able
to address remaining opt-out claims as  well  as expected  remaining
obligations  under the  Revised  Settlement  program within its reserves
described below.

In  the  fourth  quarter of 1993, the Company recorded a charge  of  $500
million  before  taxes ($310 million after taxes) in  respect  of  breast
implant  cases.  The  charge  consisted of  $1.5  billion  for  potential
liabilities  and  expenses, offset by $1.0 billion of expected  insurance
proceeds.  In the fourth quarters of 1994 and 1995, the Company  recorded
additional  special  charges of $750 million before taxes  ($488  million
after  taxes)  and $950 million before taxes ($590 million after  taxes),
respectively, related to breast implant product liability claims. In  the
fourth quarter of 1998, the Company recorded an additional special charge
to  earnings in the amount of $800 million before taxes and increased its
insurance receivable in the amount of $100 million, resulting  in  a  net
charge  to  earnings  of $433 million after taxes in  respect  of  breast
implant  product  liability  claims. During 1999,  1998  and  1997,  cash
payments,  net of insurance receipts, of $631 million, $551  million  and
$549  million,  respectively, were made related  to  the  breast  implant
product liability claims. At December 31, 1999, $354 million was included
in  current  and  other liabilities for breast implant product  liability
claims.

Prescription Drug
- -----------------

As  of  December  31,  1999, the Company remains a defendant  in  several
actions  challenging  pricing  on brand name  prescription  drugs.  These
actions  include several currently consolidated antitrust actions brought
against  the Company and more than 30 other pharmaceutical manufacturers,
drug   wholesalers  and  pharmacy  benefit  managers  by  certain   chain
drugstores,   supermarket  chains  and  independent   drugstores;   state
pharmaceutical  actions;  and  purported  class  actions  on  behalf   of
consumers. In the fourth quarter of 1998, the Company recorded a special


                                56
<PAGE>

                      BRISTOL-MYERS SQUIBB COMPANY
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                          (dollars in millions)

charge  to  earnings  in  the amount of $100 million  before  taxes  ($62
million after taxes) in respect of this prescription  drug  litigation.
The  Company  will  continue  to  defend vigorously its position in this
ongoing litigation and believes  it  will be able to address all remaining
claims within its reserves. During 1999, cash  payments of $59 million were
made related to the pricing litigation claims.

TAXOL*
- ------

There  is  no  composition of matter patent for  paclitaxel  (the  active
ingredient in TAXOL*). In the United States, the Company is presently the
only  manufacturer and marketer of a product containing  paclitaxel.   In
1997  and 1998, the Company filed several lawsuits alleging that a number
of  generic drug companies infringed its patents covering certain methods
of   administering  paclitaxel  when  they  filed  abbreviated  new  drug
applications  seeking  regulatory  approval  to  sell  paclitaxel.  These
actions  were  consolidated for discovery in the United  States  District
Court  for  the  District of New Jersey. The Company does  not  assert  a
monetary  claim against any of the defendants, but seeks to  prevent  the
defendants  from  marketing  paclitaxel in a  manner  that  violates  the
Company's patents. The defendants have asserted that they do not infringe
the   Company's   patents  and  that  these  patents  are   invalid   and
unenforceable.   Some  defendants  also  asserted  counterclaims  seeking
damages for alleged antitrust and unfair competition violations.

On  January 4, 2000, the District Court granted the Company's  motion  to
dismiss  certain  of the antitrust and unfair competition  counterclaims.
The  Company's motion for summary judgment on the remaining antitrust and
unfair competition counterclaims was denied on March 17, 2000.

On  February  29,  2000, the District Court granted in part  the  generic
companies' summary judgment motions for invalidity by finding all  claims
of the Company's patents in dispute invalid, except for claims limited to
the  treatment of ovarian cancer. As a result of this ruling, the generic
companies may obtain U.S. Food and Drug Administration approval to market
paclitaxel solely for treatment of metastatic breast cancer after failure
of  combination  chemotherapy.  The District  Court's  opinion  left  for
determination  at  trial  the validity of the  claims  of  the  Company's
patents directed to the low dose, three-hour administration of paclitaxel
for  ovarian  cancer and denied the generic companies'  summary  judgment
motion arguing non-infringement of the Company's patents. The Company may
pursue its appeal rights in the future.

The claims remaining in the lawsuits are currently scheduled for trial in
May 2000.  It is not possible at this time to make a reasonable
assessment of the outcome of the remaining claims in these actions nor to
reasonably estimate the impact on TAXOL* sales or the amount of damages
were the Company not to prevail.


While  it is not possible to predict with certainty the outcome of  these
cases, it is the opinion of management that they will not have a material
adverse   effect  on  the  Company's  operating  results,  liquidity   or
consolidated financial position.


                                        57
<PAGE>


Note 16  SELECTED QUARTERLY FINANCIAL DATA (UNAUDITED)
- ------------------------------------------------------
(in millions, except per share amounts)

                               First   Second    Third   Fourth
                              Quarter  Quarter  Quarter  Quarter     Year
1999:                         -------  -------  -------  -------  -------
Net Sales                     $4,854    $4,920   $5,040   $5,408  $20,222
Gross Profit                   3,549     3,559    3,638    3,937   14,683
Net Earnings                   1,066       952    1,097    1,052    4,167
Earnings Per Common Share
Basic                            .54       .48      .55      .53     2.10
Diluted                          .53       .47      .54      .52     2.06

1998:
Net Sales                     $4,446    $4,430   $4,523   $4,885  $18,284
Gross Profit                   3,294     3,224    3,332    3,578   13,428
Net Earnings                     927       835      966      413    3,141
Earnings Per Common Share
Basic                            .47       .42      .49      .21     1.58
Diluted                          .46       .41      .47      .20     1.55



  *   In 1998, the first quarter results included a gain on the sale of  a
  business  of $125 million ($78 million after taxes) and a provision  for
  restructuring  of  $125 million ($78 million after taxes).   The  second
  quarter results included a gain on the sale of businesses of $76 million
  ($47  million  after  taxes) and a provision for  restructuring  of  $76
  million ($47 million after taxes).  The fourth quarter results included a
  charge  of  $800 million ($495 million after taxes; or $.25  per  common
  share  -  basic  and $.24 per common share - diluted) for litigation  of
  breast  implant and prescription drug pricing cases, offset by  expected
  insurance recoveries.




                                        58
<PAGE>


                   REPORT OF INDEPENDENT ACCOUNTANTS
                   ---------------------------------


To the Board of Directors
and Stockholders of
Bristol-Myers Squibb Company



In our opinion, the consolidated financial statements listed in the index
appearing under Item 14(a)(1) on page 61 present fairly, in all  material
respects, the financial position of Bristol-Myers Squibb Company and  its
subsidiaries  at  December 31, 1999, 1998 and 1997, and  the  results  of
their  operations  and  their cash flows for  the  years  then  ended  in
conformity  with accounting principles generally accepted in  the  United
States.  In  addition, in our opinion, the financial  statement  schedule
listed  in  the index appearing under Item 14(a)(2) on page  61  presents
fairly, in all material respects, the information set forth therein  when
read  in  conjunction with the related consolidated financial statements.
These  financial statements and the financial statement schedule are  the
responsibility  of  the Company's management; our  responsibility  is  to
express  an  opinion  on  these financial statements  and  the  financial
statement schedule based on our audits. We conducted our audits of  these
statements  in accordance with auditing standards generally  accepted  in
the  United States, which require that we plan and perform the  audit  to
obtain  reasonable assurance about whether the financial  statements  are
free  of  material misstatement. An audit includes examining, on  a  test
basis,  evidence supporting the amounts and disclosures in the  financial
statements,  assessing  the accounting principles  used  and  significant
estimates  made  by  management,  and evaluating  the  overall  financial
statement  presentation. We believe that our audits provide a  reasonable
basis for the opinion expressed above.


/s/ PricewaterhouseCoopers LLP
- ------------------------------

PRICEWATERHOUSECOOPERS LLP
New York, New York
January 24, 2000

                                        59
<PAGE>

Item 9.   CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING
          AND FINANCIAL DISCLOSURE.

None.

                               PART III
                             ------------

Item 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT.

(a)  Reference is made to the Proxy Statement for the Annual Meeting of
     Stockholders on May 2, 2000 with respect to the Directors  of  the
     Registrant  which is incorporated herein by reference and  made  a
     part hereof in response to the information required by Item 10.

(b)  The  information required by Item 10 with respect to the Executive
     Officers  of the Registrant has been included in Part IA  of  this
     Form  10-K Annual Report in reliance on General Instruction  G  of
     Form 10-K and Instruction 3 to Item 401(b) of Regulation S-K.


Item 11.  EXECUTIVE COMPENSATION.

Reference  is  made  to the Proxy Statement for the Annual  Meeting  of
Stockholders  on  May  2,  2000 with respect to Executive  Compensation
which  is  incorporated herein by reference and made a part  hereof  in
response to the information required by Item 11.

Item 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
          MANAGEMENT.

Reference  is  made  to the Proxy Statement for the Annual  Meeting  of
Stockholders  on May 2, 2000 with respect to the security ownership  of
certain  beneficial owners and management which is incorporated  herein
by reference and made a part hereof in response to information required
by Item 12.

Item 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

Reference  is  made  to the Proxy Statement for the Annual  Meeting  of
Stockholders  on May 2, 2000 with respect to certain relationships  and
related transactions which is incorporated herein by reference and made
a part hereof in response to the information required by Item 13.

                                        60
<PAGE>

                                 PART IV
                              -------------

Item 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K.

                                                                  Page
                                                                 Number
                                                                 ------
(a)
 1.  Financial Statements                                        31-35
     Notes to Consolidated Financial Statements                  36-58
     Report of Independent Accountants                           59

 2.  Financial Statement Schedules

                                                  Schedule      Page
                                                   Number      Number
                                                  --------     ------

     Valuation and qualifying accounts               II          S-1

     All other schedules not included with this additional financial data
     are  omitted  because  they  are  not  applicable  or  the  required
     information  is  included  in  the  financial  statements  or  notes
     thereto.


3.  Exhibit List

The  Exhibits listed below are identified by numbers corresponding to the
Exhibit  Table of Item 601 of Regulation S-K. The Exhibits designated  by
two  asterisks  (**)  are management contracts or compensatory  plans  or
arrangements  required  to be filed pursuant to  this  Item  14.   Unless
otherwise  indicated, all Exhibits are part of Commission File Number  1-
1136.

3a.  Restated  Certificate  of  Incorporation  of  Bristol-Myers   Squibb
     Company  (incorporated  herein  by  reference  to  Exhibit   4a   to
     Registrant's   Registration  Statement  on  Form  S-3,  Registration
     Statement No. 33-33682, dated March 7, 1990, as amended through  May
     5, 1999 by Certificate of Amendment, filed herewith).

3b.  Bylaws  of Bristol-Myers Squibb Company, as amended through  January
     20, 2000, filed herewith.

4a.  Letter  of  Agreement dated March 28, 1984 (incorporated  herein  by
     reference  to  Exhibit  4 to Form 10-K for  the  fiscal  year  ended
     December 31, 1983).

4b.  Indenture,  dated  as of June 1, 1993, between Bristol-Myers  Squibb
     Company  and  The  Chase Manhattan Bank (National  Association),  as
     trustee (incorporated herein by reference to Exhibit 4.1 to the Form
     8-K dated May 27, 1993, and filed on June 3, 1993).

4c.  Form  of  7.15%  Debenture Due 2023 of Bristol-Myers Squibb  Company
     (incorporated  herein by reference to Exhibit 4.2 to  the  Form  8-K
     dated May 27, 1993, and filed on June 3, 1993).

                                        61
<PAGE>

4d.    Form  of  6.80%  Debenture Due 2026 of Bristol-Myers Squibb  Company
       (incorporated herein by reference to Exhibit 4e to the Form 10-K for
       the fiscal year ended December 31, 1996).

4e.    Form  of  6.875% Debenture Due 2097 of Bristol-Myers Squibb  Company
       (incorporated herein by reference to Exhibit 4f to the Form 10-Q for
       the quarterly period ended September 30, 1997).

4f.    Five   Year  Competitive  Advance  and  Revolving  Credit   Facility
       Agreement  dated  as  of March 17, 1998 among  Bristol-Myers  Squibb
       Company,  the Borrowing Subsidiaries (as defined in the  Agreement),
       the  Lenders  listed  in Schedule 2.1 to the  Agreement,  The  Chase
       Manhattan  Bank  as  Administrative Agent  and  Citibank,  N.A.,  as
       Administrative Agent (incorporated herein by reference to Exhibit 4f
       to the Form 10-K for the fiscal year ended December 31, 1997).

4g.    364-Day  Competitive Advance and Revolving Credit Facility agreement
       dated  as of March 17, 1998 among Bristol-Myers Squibb Company,  the
       Borrowing  Subsidiaries (as defined in the Agreement),  the  Lenders
       listed in Schedule 2.1 to the Agreement, The Chase Manhattan Bank as
       Administrative  Agent  and Citibank, N.A., as  Administrative  Agent
       (incorporated herein by reference to Exhibit 4g to the Form 10-K for
       the fiscal year ended December 31, 1997).

**10a. Bristol-Myers  Squibb  Company  1997  Stock  Incentive  Plan,
       effective  as  of May 6, 1997 and as amended effective  November  3,
       1998 (incorporated herein by reference to Exhibit 4g to the Form 10-
       K for the fiscal year ended December 31, 1998).

**10b. Bristol-Myers  Squibb Company Executive Performance  Incentive
       Plan (incorporated herein by reference to Exhibit 10b to the Form 10-
       K for the fiscal year ended December 31, 1996).

**10c. Bristol-Myers Squibb Company 1983 Stock Option Plan, as amended
       and  restated  as  of January 1, 1997, as amended November  3,  1998
       (incorporated herein by reference to Exhibit 4g to the Form 10-K for
       the fiscal year ended December 31, 1998).

**10d. Squibb   Corporation  1982  Option,  Restricted   Stock   and
       Performance Unit Plan, as amended (incorporated herein by  reference
       to  Exhibit 10b to the Form 10-K for the fiscal year ended  December
       31, 1993).

**10e. Squibb   Corporation  1986  Option,  Restricted   Stock   and
       Performance  Unit Plan, as amended (as adopted, incorporated  herein
       by  reference to Exhibit 10k to the Squibb Corporation Form 10-K for
       the fiscal year ended December 31, 1988, File No. 1-5514; as amended
       effective  July  1, 1993, and incorporated herein  by  reference  to
       Exhibit 10c to the Form 10-K for the fiscal year ended December  31,
       1993).

**10f. Bristol-Myers  Squibb Company Performance Incentive  Plan,  as
       amended  (as adopted, incorporated herein by reference to Exhibit  2
       to  the  Form 10-K for the fiscal year ended December 31,  1978;  as
       amended  as of January 8, 1990, incorporated herein by reference  to
       Exhibit 19b to the Form 10-K for the fiscal year ended December  31,
       1990;  as amended on April 2, 1991, incorporated herein by reference
       to  Exhibit 19b to the Form 10-K for the fiscal year ended  December
       31,  1991; as amended effective January 1, 1994, incorporated herein
       by reference to Exhibit 10d to the Form 10-K for the
       fiscal  year  ended  December 31, 1993;  and  as  amended  effective
       January 1, 1994, incorporated herein by reference to Exhibit 10d  to
       the Form 10-K for the fiscal year ended December 31, 1994).

                                        62
<PAGE>

**10g. Benefit Equalization Plan of Bristol-Myers Squibb Company  and
       its  Subsidiary  or  Affiliated Corporations  Participating  in  the
       Bristol-Myers Squibb Company Retirement Income Plan or the  Bristol-
       Myers  Squibb Puerto Rico, Inc. Retirement Income Plan,  as  amended
       (as amended and restated as of January 1, 1993, as amended effective
       October 1, 1993, incorporated herein by reference to Exhibit 10e  to
       the  Form 10-K for the fiscal year ended December 31, 1993;  and  as
       amended effective February 1, 1995, incorporated herein by reference
       to  Exhibit 10e to the Form 10-K for the fiscal year ended  December
       31, 1996).

**10h. Benefit Equalization Plan of Bristol-Myers Squibb Company  and
       its  Subsidiary  or  Affiliated Corporations  Participating  in  the
       Bristol-Myers  Squibb  Company Savings and  Investment  Program,  as
       amended  (as  amended and restated as of May 1,  1990,  incorporated
       herein  by reference to Exhibit 19d to the Form 10-K for the  fiscal
       year  ended  December 31, 1990; as amended as of  January  1,  1991,
       incorporated herein by reference to Exhibit 19g to the Form 10-K for
       the fiscal year ended December 31, 1990; as amended as of January 1,
       1991, incorporated herein by reference to Exhibit 19e to the Form 10-
       K  for  the  fiscal year ended December 31, 1991, as amended  as  of
       October 1, 1994, incorporated herein by reference to Exhibit 10f  to
       the Form 10-K for the fiscal year ended December 31, 1994).

**10i. Squibb Corporation Supplementary Pension Plan, as amended  (as
       previously amended and restated, incorporated herein by reference to
       Exhibit 19g to the Form 10-K for the fiscal year ended December  31,
       1991;  as amended as of September 14, 1993, and incorporated  herein
       by  reference  to Exhibit 10g to the Form 10-K for the  fiscal  year
       ended December 31, 1993).

**10j. Bristol-Myers Squibb Company Restricted Stock Award  Plan,  as
       amended  (as  adopted  on November 7, 1989, incorporated  herein  by
       reference to Exhibit 10t to the Form 10-K for the fiscal year  ended
       December  31,  1989;  as amended on December 4,  1990,  incorporated
       herein  by reference to Exhibit 19a to the Form 10-K for the  fiscal
       year  ended  December 31, 1990; as amended effective July  1,  1993,
       incorporated herein by reference to Exhibit 10h to the Form 10-K for
       the  fiscal  year  ended  December 31, 1993;  as  amended  effective
       December 6, 1994, incorporated herein by reference to Exhibit 10h to
       the Form 10-K for the fiscal year ended December 31, 1994).

**10k. Bristol-Myers Squibb Company Retirement Income Plan  for  Non-
       Employee Directors, as amended to March 5, 1996 (incorporated herein
       by  reference  to Exhibit 10k to the Form 10-K for the  fiscal  year
       ended December 31, 1996).

**10l. Bristol-Myers  Squibb Company 1987 Deferred Compensation  Plan
       for   Non-Employee  Directors,  as  amended  to  January  13,  1998,
       (incorporated  herein by reference to Exhibit 10l to the  Form  10-K
       for the fiscal year ended December 31, 1997).

**10m. Bristol-Myers Squibb Company Non-Employee Directors'  Stock  Option
       Plan,  as  amended (as approved by the Stockholders on May 1,  1990,
       incorporated  herein  by  reference to Exhibit  28  to  Registration
       Statement  No.  33-38587  on  Form S-8;  as  amended  May  7,  1991,
       incorporated herein by reference to Exhibit 19c to the Form 10-K for
       the  fiscal  year ended December 31, 1991), as amended  January  12,
       1999 (incorporated herein by reference to Exhibit 4g to the Form 10-
       K for the fiscal year ended December 31, 1998).

**10n. Squibb Corporation Deferral Plan for Fees of Outside Directors,
       as  amended (as adopted, incorporated herein by reference to Exhibit
       10e  to  the Squibb Corporation Form 10-K for the fiscal year  ended

                                        63
<PAGE>

       December  31,  1987, File No. 1-5514; as amended effective  December
       31,  1991,  incorporated herein by reference to Exhibit 10m  to  the
       Form 10-K for the fiscal year ended December 31, 1992).

**10o. Amendment  to  all of the Company's plans,  agreements,  legal
       documents  and other writings, pursuant to action of  the  Board  of
       Directors on October 3, 1989, to reflect the change of the Company's
       name  to  Bristol-Myers  Squibb  Company  (incorporated  herein   by
       reference to Exhibit 10v to the Form 10-K for the fiscal year  ended
       December 31, 1989).

**10p. Employment agreement of March 12, 1999 for Charles A. Heimbold,
       Jr. (incorporated herein by reference to Exhibit 4g to the Form 10-K
       for the fiscal year ended December 31, 1998).

**10q. Form  of  Agreement, effective June 1, 1999,  entered  into
       between  the Registrant and each of the following officers  on
       the following dates: Peter R. Dolan, July 29, 1999; Donald  J.
       Hayden,  Jr., July 30, 1999; Richard J. Lane, August 6,  1999;
       John L. McGoldrick, August 10, 1999; Michael F. Mee, July  28,
       1999;  Christine  A. Poon, July 29, 1999; Peter  S.  Ringrose,
       Ph.D.,  August  5,  1999; Stephen I. Sadove,  July  29,  1999;
       Frederick  S. Schiff, July 29, 1999; John L. Skule, August  5,
       1999;  Charles G. Tharp, Ph.D., July 28, 1999; and Kenneth  E.
       Weg,  July  29,  1999. (incorporated herein  by  reference  to
       Exhibit  10q  to the Form 10-Q for the quarterly period  ended
       September 30, 1999).

21.    Subsidiaries of the Registrant (filed herewith).

23.    Consent of PricewaterhouseCoopers LLP(filed herewith).

27.    Bristol-Myers Squibb Company Financial Data Schedule (filed
       herewith).

99.    Additional Exhibit (filed herewith).


(b)  Reports on Form 8-K

        None.

                                        64
<PAGE>

                                SIGNATURES
                           --------------------

Pursuant  to  the requirements of Section 13 or 15 (d) of  the  Securities
Exchange  Act  of 1934, the Registrant has duly caused this Report  to  be
signed on its behalf by the undersigned, thereunto duly authorized.


                                       BRISTOL-MYERS SQUIBB COMPANY
                                               (Registrant)


                                           By  /s/   Charles A. Heimbold, Jr.

                                           ----------------------------------
                                           Charles A. Heimbold, Jr.
                                           Chairman of the Board and
                                           Chief Executive Officer

                                                March 30, 2000
                                           ----------------------------------
                                                Date


Pursuant to the requirements of the Securities Exchange Act of 1934,  this
Report  has  been signed below by the following persons on behalf  of  the
Registrant and in the capacities and on the dates indicated.


 Signature                              Title                        Date
 ------------                          --------                      ----
                                 Chairman of the Board,
                                 Chief Executive Officer
                                 And Director (Principal
/s/  Charles A. Heimbold, Jr.    Executive Officer)              March 30, 2000
- ------------------------------
   (Charles A. Heimbold, Jr.)

                                 Chief Financial Officer
                                 and Executive Vice President
                                 Corporate Staff (Principal
/s/  Michael F. Mee              Financial Officer)              March 30, 2000
- ------------------------------
   (Michael F. Mee)

                                 Controller and Senior Vice
                                 President, Financial Operations,
                                 Corporate Staff (Principal
/s/  Frederick S. Schiff         Accounting Officer)             March 30, 2000
- ------------------------------
   (Frederick S. Schiff)


                                        65
<PAGE>

Signature                               Title                        Date
- --------                                ------                       ----

/s/   Robert E. Allen            Director                        March 30, 2000
- -----------------------------
    (Robert E. Allen)

/s/ Lewis B. Campbell            Director                        March 30, 2000
- -----------------------------
    (Lewis B. Campbell)

/s/  Vance D. Coffman            Director                        March 30, 2000
- -----------------------------
    (Vance D. Coffman)

/s/  Peter R. Dolan              President and Director          March 30, 2000
- -----------------------------
    (Peter R. Dolan)

/s/   Ellen  V. Futter           Director                        March 30, 2000
- -----------------------------
    (Ellen V. Futter)

/s/   Louis  V. Gerstner, Jr.    Director                        March 30, 2000
- -----------------------------
    (Louis V. Gerstner, Jr.)

/s/   Laurie H. Glimcher, M.D.   Director                        March 30, 2000
- -----------------------------
    (Laurie H. Glimcher, M.D.)

/s/   Leif  Johansson            Director                        March 30, 2000
- -----------------------------
    (Leif Johansson)

/s/  James D. Robinson III       Director                        March 30, 2000
- -----------------------------
    (James D. Robinson III)

/s/   Louis  W. Sullivan, M.D.   Director                        March 30, 2000
- -----------------------------
    (Louis W. Sullivan, M.D.)

                                 Vice Chairman,
/s/  Kenneth E. Weg              and Director                    March 30, 2000
- ----------------------------
    (Kenneth E. Weg)


                                        66
<PAGE>

                            EXHIBIT INDEX
                       -----------------------

The  Exhibits listed below are identified by numbers corresponding  to
the Exhibit Table of Item 601 of Regulation S-K. The Exhibits designed
by  two asterisks (**) are management contracts or compensatory  plans
or  arrangements required to be filed pursuant to this  Item  14.   An
asterisk  (*) in the Page column indicates that the Exhibit  has  been
previously  filed  with the Commission and is incorporated  herein  by
reference.   Unless  otherwise indicated, all  Exhibits  are  part  of
Commission File Number 1-1136.

      Exhibit Number and Description                                    Page
      ------------------------------                                   -----

 3a.  Restated Certificate of Incorporation of Bristol-Myers Squibb    E-1-1
      Company (incorporated herein by reference to Exhibit 4a to
      Registration Statement No. 33-33682 on Form S-3, dated March
      7, 1990, as amended through May 5, 1999 by Certificate of
      Amendment filed herewith).

 3b.  Bylaws of Bristol-Myers Squibb Company, as amended through       E-2-1
      January 20, 2000.

 4a.  Letter of Agreement dated March 28, 1984 (incorporated           *
      herein by reference to Exhibit 4 to Form 10-K for the fiscal
      year ended December 31,1983).

 4b.  Indenture, dated as of June 1, 1993, between Bristol-Myers       *
      Squibb Company and The Chase Manhattan Bank (National
      Association),as trustee (incorporated herein by reference to
      Exhibit 4.1 to the Form 8-K dated May 27, 1993, and filed on
      June 3, 1993).

 4c.  Form of 7.15% Debenture Due 2023 of Bristol-Myers Squibb         *
      Company (incorporated herein by reference to Exhibit 4.2 to the
      Form 8-K dated May 27, 1993, and filed on June 3, 1993).

 4d.  Form of 6.80% Debenture Due 2026 of Bristol-Myers Squibb         *
      Company (incorporated herein by reference to Exhibit 4e to the
      Form 10-K for the fiscal year ended December 31, 1996).

 4e.  Form of 6.875% Debenture Due 2097 of Bristol-Myers Squibb        *
      Company (incorporated herein by reference to Exhibit 4f to the
      Form 10-Q for the quarterly period ended September 30, 1997).





                                        67
<PAGE>


        Exhibit Number and Description                                  Page
        ------------------------------                               -------

 4f.    Five Year Competitive Advance and Revolving Credit Facility      *
        Agreement dated as of March 17, 1998 among Bristol-Myers Squibb
        Company, the Borrowing Subsidiaries (as defined in the
        Agreement), the Lenders listed in Schedule 2.1 to the Agreement,
        The Chase Manhattan Bank as Administrative Agent and
        Citibank, N.A., as Administrative Agent.

 4g.    364-Day   Competitive  Advance  and  Revolving  Credit  Facility
        Agreement dated as of March 17, 1998 among Bristol-Myers Squibb
        Company, the Borrowing Subsidiaries (as defined in the Agreement
        the Lenders listed in Schedule 2.1 to the Agreement, The Chase
        Manhattan Bank as Administrative Agent and Citibank, N.A.,
        as Administrative Agent.

** 10a. Bristol-Myers Squibb Company 1997 Stock Incentive Plan,          *
        effective as of May 6, 1997 and as amended effective
        November 3, 1998 (incorporated herein by reference to Exhibit
        10a  to  the  Form 10-K for the fiscal year ended  December  31,
        1998).

** 10b. Bristol-Myers  Squibb  Company Executive  Performance  Incentive *
        Plan (incorporated herein by reference to Exhibit 10b to the
        Form 10-K for the fiscal year ended December 31, 1996).

** 10c. Bristol-Myers Squibb Company 1983 Stock Option Plan, as          *
        amended and restated as of January 1, 1997, as amended
        November 3, 1998 (incorporated herein by reference to Exhibit
        10c  to  the  Form 10-K for the fiscal year ended  December  31,
        1998).

** 10d. Squibb Corporation 1982 Option, Restricted Stock and             *
        Performance Unit Plan, as amended (incorporated by reference
        to Exhibit 10b to the Form 10-K for the fiscal year ended
        December 31, 1993).

** 10e. Squibb Corporation 1986 Option, Restricted Stock and Performance *
        Unit Plan, as amended (as adopted, incorporated herein by
        reference to  Exhibit  10k to the Squibb Corporation Form  10-K
        for  the fiscal year ended December 31, 1988, File No. 1-5514,
        as amended July  1, 1993, incorporated herein by reference to
        Exhibit  10c to the Form 10-K for the fiscal year ended December
        31, 1993).

                                        68
<PAGE>

        Exhibit Number and Description                                  Page
        ------------------------------                                ------

** 10f. Bristol-Myers Squibb Company Performance Incentive Plan, as      *
        amended (as adopted, incorporated herein by reference to
        Exhibit 2 to  the Form 10-K for the fiscal year ended
        December 31, 1978; as amended as of January 8, 1990,
        incorporated herein by reference to Exhibit 19b to the Form
        10-K for the fiscal year ended December 31, 1990; as amended
        on April 2, 1991, incorporated herein  by  reference to
        Exhibit 19b to the Form 10-K  for  the fiscal year ended
        December 31, 1991; as amended effective on January 1,1994,
        and incorporated herein by reference to Exhibit  10d  to
        the Form 10-K for the fiscal year ended December 31, 1994).

** 10g. Benefit Equalization Plan of Bristol-Myers Squibb Company        *
        and its Subsidiary  or  Affiliated corporations  Participating
        in  the Bristol-Myers Squibb  Company  Retirement Income Plan
        or  the  Bristol-Myers Squibb Puerto  Rico,  Inc.  Retirement
        Income  Plan, as amended (as amended and restated as of January
        1, 1993,  as  amended  effective October 1, 1993, incorporated
        herein by reference to Exhibit 10e to the Form 10-K for the
        fiscal  year  ended  December 31, 1993  and  amended  effective
        February 1, 1995, incorporated by reference to Exhibit 10e to
        the Form 10-K for the fiscal year ended December 31, 1995).

** 10h. Benefit Equalization Plan of Bristol-Myers Squibb Company        *
        and its Subsidiary or Affiliated Corporation Participating
        in the Bristol-Myers Squibb Company Savings and Investment
        Program, as amended (as amended and restated as of
        May 1, 1990, incorporated herein by reference to Exhibit 19d
        to the Form 10-K for the fiscal year ended December 31, 1990;
        as amended as of January 1, 1991, incorporated herein by
        reference to Exhibit 19g to the Form 10-K for the fiscal year
        ended December 31, 1990; as amended as of January 1, 1991,
        incorporated herein by reference to Exhibit 19e to the Form 10-
        K for the fiscal year ended December 31, 1991; as amended as of
        October  1,  1994, incorporated herein by reference to  Exhibit
        10f of the Form 10-K for the fiscal year ended December 31, 1994).

** 10i. Squibb Corporation Supplementary Pension Plan, as amended (as    *
        previously amended and restated, incorporated herein by
        reference to Exhibit 19g to the Form 10-K for the fiscal year
        ended December 31, 1991; as amended on September 14, 1993,
        incorporated by reference to Exhibit 10g to the Form 10-K
        for the fiscal year ended December 31, 1993).


                                        69
<PAGE>

        Exhibit Number and Description                                  Page
        ------------------------------                                ------

** 10j. Bristol-Myers Squibb Company Restricted Stock Award Plan, as     *
        amended (as adopted on November 7, 1989, incorporated herein
        by reference to Exhibit 10t to the Form 10-K for the fiscal
        year ended December 31, 1989; as amended on December 4, 1990,
        incorporated herein by reference to Exhibit 19a to the
        Form 10-K for the fiscal year ended December 31, 1990; as
        amended July 1, 1993, incorporated by reference to Exhibit 10h
        to the Form 10-K for the fiscal year ended December 31, 1993;
        as amended effective December 6, 1994, incorporated by
        reference to Exhibit 10h to the Form 10-K for the fiscal year
        Ended January 31, 1994).

** 10k. Bristol-Myers Squibb Company Retirement Income Plan for          *
        Non-Employee Directors, as amended to March 5,1996
        (incorporated herein by reference to Exhibit 10k to the
        Form 10-K for the fiscal year ended December 31, 1996).

** 10l. Bristol-Myers Squibb Company 1987 Deferred Compensation          *
        Plan for Non-Employee Directors, as amended to January 13,
        1998, (incorporated herein by reference to Exhibit 10l to
        the Form 10-K for the fiscal year ended December 31, 1997).

** 10m. Bristol-Myers Squibb Company Non-Employee Directors' Stock       *
        Option Plan, as amended (as approved by the Stockholders on
        May 1, 1990, incorporated herein by reference to Exhibit 28
        to Registration Statement No. 33-38587 on Form S-8; as amended
        May 7, 1991, incorporated herein by reference to Exhibit 19c to
        the Form 10-K for the fiscal year ended December 31, 1991; as
        amended January 12, 1999, incorporated herein by reference to
        Exhibit 10m to the Form 10-K for the fiscal year ended December
        31, 1998).

** 10n. Squibb Corporation Deferral Plan for Fees of Outside Directors,  *
        as amended (as adopted, incorporated herein by reference to
        Exhibit 10e to the Squibb Corporation Form 10-K for the
        fiscal year ended December 31, 1987, File No. 1-5514; as
        amended effective December 31, 1991, incorporated herein
        by reference to Exhibit 10m to the Form 10-K for the fiscal
        year ended December 31, 1992).



                                        70
<PAGE>

        Exhibit Number and Description                                  Page
        ------------------------------                                ------

** 10o. Amendment to all of the Company's plans, agreements, legal       *
        documents and other writings, pursuant to action of the Board
        of Directors on October 3, 1989, to reflect the change of the
        Company's name to Bristol-Myers Squibb Company (incorporated
        herein by reference to Exhibit 10v to the Form 10-K for the
        fiscal year ended December 31, 1989).

** 10p. Employment agreement of March 12, 1999 for Charles A.            *
        Heimbold, Jr. (incorporated herein by reference to Exhibit
        10p to the Form 10-K for the fiscal year ended December 31,
        1998).

** 10q. Form of Agreement, effective June 1, 1999, entered into          *
        between the Registrant and each of the following officers on
        the following dates: Peter R. Dolan, July 29, 1999; Donald J.
        Hayden, Jr., July 30, 1999; Richard J. Lane, August 6, 1999;
        John L. McGoldrick, August 10, 1999; Michael F. Mee, July 28,
        1999; Christine A. Poon, July 29, 1999; Peter S. Ringrose,
        Ph.D., August 5, 1999; Stephen I. Sadove, July 29, 1999;
        Frederick S. Schiff, July 29, 1999; John L. Skule, August 5,
        1999; Charles G. Tharp, Ph.D., July 28, 1999; and Kenneth E.
        Weg, July 29, 1999. (incorporated herein by reference to
        Exhibit 10q to the Form 10-Q for the quarterly period ended
        September 30, 1999).


21.     Subsidiaries of the Registrant.                                  E-3-1

23.     Consent of PricewaterhouseCoopers LLP.                           E-4-1

27.     Bristol-Myers Squibb Company Financial Data Schedule.            E-5-1

99.     Additional Exhibit                                               E-6-1

                                        71
<PAGE>

                                                     SCHEDULE II
                                                ---------------------

                       BRISTOL-MYERS SQUIBB COMPANY
                     VALUATION AND QUALIFYING ACCOUNTS
                           (dollars in millions)



                              Additions
                  Balance at  charged to   Deductions-    Balance at
                  beginning   costs and     bad debts        end
Description       of period    expenses    written off     of period
- -----------      -----------  ----------  ------------    -----------

Allowances for
  discounts and
  doubtful accounts:

For the year ended
  December 31, 1999    $147        $65          $44            $168


For the year ended
  December 31, 1998    $109        $57          $19            $147


For the year ended
  December 31, 1997    $107        $19          $17            $109









                                        S-1


                  CERTIFICATE OF AMENDMENT

                             OF

                CERTIFICATE OF INCORPORATION

                          * * * * *



     Bristol-Myers Squibb Company, a corporation organized

and existing under and by virtue of the General Corporation

Law of the State of Delaware, DOES HEREBY CERTIFY:

     FIRST:   That at a meeting of the Board of Directors of

December 1, 1998 resolutions were duly adopted setting forth

a proposed amendment to the Certificate of Incorporation of

said corporation, declaring said amendment to be advisable

and calling a meeting of the stockholders of said

corporation for consideration thereof.  The resolution

setting forth the proposed amendment is as follows:

          RESOLVED, That the Certificate of Incorporation of
          this corporation be amended by changing the FOURTH
          Article thereof so that, as amended said Article
          shall be and read as follows:

               "FOURTH:   the total number of shares of all
          classes of stock which the corporation shall have
          authority to issue is four billion, five-hundred
          ten million (4,510,000,000) shares consisting of:

                    1.   4,500,000,000 shares of Common Stock of the par value
                      of Ten Cents ($0.10) per share, and

                    2.   10,000,000 shares of Preferred Stock of the par value
                      of
                      One Dollar ($1.00) per share."

     SECOND:   That thereafter, pursuant to resolution of

its Board of Directors, the Annual Meeting of Stockholders

of said corporation was duly called and held May 4, 1999,

upon notice in accordance with Section 222 of the General

Corporation Law of the



                            E-1-1

<PAGE>


State of Delaware, at which meeting the necessary number of

shares as required by statute were voted in favor of the

amendment.

     THIRD:   That said amendment was duly adopted in

accordance with the provisions of Section 242 of the General

Corporation Law of the State of Delaware.

     IN WITNESS WHEREOF, said corporation has caused this

certificate to be signed by Alice C. Brennan, its Vice

President and Secretary, this 5th day of May, 1999.



                              By:  /s/ Alice C. Brennan
                                   ______________________
                                   Vice President & Secretary



                            E-1-2





 --------------------------------------------------------------------------






                            BRISTOL-MYERS SQUIBB COMPANY







                                  ---------------


                                      BYLAWS





                            As Adopted on November 1, 1965

                          And as Amended to January 20, 2000






                                  ---------------








 --------------------------------------------------------------------------


                                        E-2-1

<PAGE>


                                        INDEX




BYLAW NO.   SUBJECT                                                   Page No.


 1.         Principal Office                                           E-2-5

 2.         Other Offices                                              E-2-5

 3.         Seal                                                       E-2-5

 4.         Meetings of Shareholders -- Date and Time                  E-2-5

 5.         Meetings of Shareholders -- Place                          E-2-6

 6.         Meetings of Shareholders -- No Action By Written
               Consent, Call                                           E-2-6

 7.         Meetings of Shareholders -- Notice                         E-2-6

 8.         Meetings of Shareholders -- Quorum                         E-2-6

 9.         Meetings of Shareholders -- Presiding Officer and
               Secretary                                               E-2-7

10.         Meetings of Shareholders -- Voting                         E-2-7

11.         Meetings of Shareholders -- Voting List                    E-2-7

12.         Annual Meeting of Shareholders -- Statement of Business
               and Condition of Company                                E-2-7

13.         Meetings of Shareholders -- Inspectors of Election         E-2-7

14.         Board of Directors -- Powers                               E-2-8

15.         Board of Directors -- Number, Election, Term, Resignation
               or Retirement, Removal and Filling Vanancies            E-2-8

16.         Board of Directors -- Location of Meetings and Books       E-2-9

17.         Board of Directors -- Scheduling of Regular Meetings       E-2-9

18.         Board of Directors -- Scheduling of Special Meetings       E-2-9



                                    E-2-2


<PAGE>



BYLAW NO.   SUBJECT                                                  Page No.


19.         Board of Directors -- Waiver of Meeting Notice and
               Action by Consent                                       E-2-9

20.         Board of Directors -- Quorum for Meeting                   E-2-9

21.         Board of Directors -- Meeting Procedure                   E-2-10

22.         Board of Directors -- Fees                                E-2-10

23.         Board of Directors -- Indemnification                     E-2-10

24.         Committees of the Board -- Executive, Audit, Others       E-2-11

25.         Committees of the Board -- Minutes and Reports            E-2-12

26.         Officers                                                  E-2-12

27.         Officers -- Election and Term                             E-2-12

28.         Appointment of Other Officers, Committees or Agents       E-2-13

29.         Officers -- Removal                                       E-2-13

30.         Officers -- Resignation                                   E-2-13

31.         Officers -- Unable to Perform Duties                      E-2-13

32.         Officers -- Vacancy                                       E-2-13

33.         The Chairman of the Board -- Powers and Duties            E-2-13

34.         Vice Chairman of the Board -- Powers and Duties           E-2-13

35.         Duties of President                                       E-2-13

36.         Vice Presidents -- Powers and Duties                      E-2-14

37.         The Treasurer -- Powers and Duties                        E-2-14





                                   E-2-3

<PAGE>


BYLAW NO.   SUBJECT                                                  Page No.


38.         The Secretary -- Powers and Duties                        E-2-14

39.         The Controller -- Powers and Duties                       E-2-14

40.         Assistant Treasurers and Assistant Secretaries --
               Powers and Duties                                      E-2-14

41.         Officers -- Compensation                                  E-2-14

42.         Contracts, Other Instruments, Authority to Enter
               Into or Execute                                        E-2-15

43.         Loans and Negotiable Paper                                E-2-15

44.         Checks, Drafts, etc.                                      E-2-15

45.         Banks -- Deposit of Funds                                 E-2-15

46.         Stock Certificates -- Form, Issuance                      E-2-15

47.         Stock -- Transfer                                         E-2-15

48.         Stock Certificates -- Loss, Replacement                   E-2-16

49.         Record Dates                                              E-2-16

50.         Registered Shareholders                                   E-2-16

51.         Fiscal Year                                               E-2-17

52.         Notices                                                   E-2-17

53.         Notices -- Waiver                                         E-2-17

54.         Amendments of Bylaws                                      E-2-17










                                    E-2-4

<PAGE>


                                    BYLAWS


                                      of



                          BRISTOL-MYERS SQUIBB COMPANY




OFFICES.


1. The registered office of the Company shall be in the City of Wilmington,
County of New Castle, State of Delaware, and the name of the resident agent
in charge thereof is The Corporation Trust Company.

2. The Company may also have offices at such place or places as the Board of
Directors may from time to time appoint or the business of the Company may
require.



SEAL.

3. The corporate seal shall have inscribed thereon the name of the Company,
the year of its organization and the words "Corporate Seal, Delaware."  Said
seal may be used in causing it or a facsimile thereof to be impressed or
affixed or reproduced or otherwise.



MEETINGS OF SHAREHOLDERS.

4. The annual meeting of the shareholders for the election of directors and
for the transaction of any other proper business shall be held at such time
as the Board of Directors may determine.  For nominations or other business
to be properly brought before any annual meeting by a shareholder, a
shareholder must give timely notice in writing thereof to the Secretary of
the Company and, in the case of business other than nominations, such other
business must be a proper matter for shareholder action.  To be considered
timely, a shareholder's notice must be received by the Secretary at the
principal executive offices of the Company not less than 120 calendar days
before the date of the Company's proxy statement released to shareholders in
connection with the prior year's annual meeting.  If the annual meeting for
the election of directors is not held on the date designated therefor, the
directors shall cause the meeting to be held as soon thereafter as convenient.
A shareholder's notice shall set forth: (a) as to each person whom the
shareholder proposes to nominate for election or re-election as a director,
all information relating to such person that is required to be disclosed in
solicitations of proxies for election of directors pursuant to Regulation 14A
under the Securities Exchange Act of 1934, including such person's written
consent to being named in the proxy statement as a nominee and to serving as
a director if elected; (b) as to any other business that the shareholder
proposes to bring before the meeting, a brief description of the business
desired to be brought before the meeting, the reasons for conducting such
business at the meeting and any material interest in such business of such
shareholder and the beneficial owner, if any, on whose behalf the proposal
is made and (c) as to

                                  E-2-5


the shareholder giving the notice and the beneficial owner, if any, on
whose behalf the nomination or proposal is made (i) the name and address of
such shareholder, as they appear on the Company's books, and of such
beneficial owner, (ii) the number of shares of stock held of record and
beneficially by such shareholder and such beneficial owner, (iii) the name
in which all such shares of stock are registered on the stock transfer books
of the Company, (iv) a representation that the shareholder intends to appear
at the meeting in person or by proxy to submit the business specified in such
notice, (v) a brief description of the business desired to be submitted to
the annual meeting, including the complete text of any resolutions intended to
be presented at the annual meeting, and the reasons for conducting such
business at the annual meeting, (vi) any personal or other material interest
of the shareholder in the business to be submitted, and (vii) all other
information relating to the proposed business which may be required to be
disclosed under applicable law.  In addition, a shareholder seeking to submit
such business at the meeting shall promptly provide any other information
reasonably requested by the Company.  The chairman of the meeting shall
determine all matters relating to the efficient conduct of the meeting,
including, but not limited to, the items of business, as well as the
maintenance of order and decorum.  The chairman shall, if the facts warrant,
determine and declare that any putative business was not properly brought
before the meeting in accordance with the procedures prescribed by this bylaw,
in which case such business shall not be transacted.  Notwithstanding the
foregoing provisions of this bylaw, a shareholder who seeks to have any
proposal included in the Company's proxy materials shall comply with the
requirements of Rule 14a-8 under Regulation 14A of the Securities Exchange
Act of 1934.

5. Meetings of the shareholders may be held at such places either within or
without the State of Delaware as the Board of Directors may determine.


6. Any action required or permitted to be taken by the stockholders of the
Company must be effected at a duly called annual or special meeting of such
stockholders and may not be effected by any consent in writing by such
stockholders.  Except as otherwise required by law and subject to the rights
under Article FOURTH of the Certificate of Incorporation of the Company of
the holders of any class or series of stock having a preference over the
Common Stock as to dividends or upon liquidation, special meetings of
stockholders of the Company may be called only by the Chairman of the Board
or by the Board of Directors pursuant to a resolution approved by a majority
of the entire Board of Directors.

7. Except as hereinafter provided or as may be otherwise required by law,
notice of the place, date and hour of holding each annual and special meeting
of the shareholders shall be in writing and shall be delivered personally or
mailed in a postage prepaid envelope, not less than ten days before such
meeting, to each person who appears on the books of the Company as a
shareholder entitled to vote at such meeting, and to any shareholders who,
by reason of any action proposed at such meeting, would be entitled to have
their shares appraised if such action were taken.  The notice of every special
meeting, besides stating the time and place of such meeting, shall state
briefly the purpose or purposes thereof; and no business other than that
specified in such notice or germane thereto shall be transacted at the
meeting, except with the unanimous consent in writing of the holders of record
of all of the shares of the Company entitled to vote at such meeting.  Notice
of any meeting of shareholders shall not be required to be given to any
shareholder entitled to participate in any action proposed to be taken at
such meeting who shall attend such meeting in person or by proxy or who
before or after any such meeting shall waive notice thereof in writing or by
telegram, cable or wireless.  Notice of any adjourned meeting need not be given.

8. At all meetings of shareholders of the Company, except as otherwise
provided by law, the holders of a majority in number of the outstanding shares
of the Company, present in person or by proxy and entitled to vote thereat,
shall constitute a quorum for the transaction of business.  In the absence of
a quorum the holders of a majority in number of the shares of stock so present
or represented and entitled to vote may adjourn the meeting from time to time
until a quorum is present.  At any such adjourned meeting at which a quorum
is present any business may be transacted which might have been transacted at
the meeting as originally called.

                                   E-2-6

<PAGE>


9. The Chairman of the Board shall preside as chairman at every meeting of
shareholders.  The Chairman of the Board may designate another officer of the
Company or any shareholder to preside as chairman of a meeting of shareholders
in place of the Chairman of the Board and in the absence of the Chairman of
the Board and an officer or shareholder designated by the Chairman of the
Board to preside as chairman of the meeting, the Board of Directors may
designate an officer or shareholder to preside as chairman of the meeting.
In the event the Chairman of the Board and the Board of Directors fail to so
designate a chairman of the meeting the shareholders may designate an officer
or shareholder as chairman.  The Secretary shall act as secretary of the
meeting, or, in the absence of the Secretary, the presiding officer shall
appoint a secretary of the meeting.

10. At each meeting of the shareholders every shareholder of record entitled
to vote thereat shall be entitled to one vote for each share of the Company
standing in that shareholder's name on the books of the Company provided that
no share of stock shall be voted at any election of directors which shall
have been transferred on the books of the Company later than the record date
announced by the Board of Directors or fixed by operation of these bylaws
The vote on shares may be given by the shareholder entitled thereto in person
or by proxy duly appointed by an instrument in writing subscribed by such
shareholder or that shareholder's duly authorized attorney (or in any other
manner prescribed by the General Corporation Law of the State of Delaware),
and delivered to the secretary of the meeting; provided, however, that no
proxy shall be valid after the expiration of three years from the date of
its execution unless the shareholder executing it shall have specified
therein the length of time it is to continue in force, which shall be for
some limited period.  At all meetings of shareholders, a quorum being present,
all matters, except as otherwise provided by law or by the Certificate of
Incorporation of the Company or these bylaws, shall be decided by the holders
of a majority in number of the shares of stock of the Company present in
person or by proxy and entitled to vote.  A share vote may be by ballot and
each ballot shall state the name of the shareholder voting and the number
of shares owned by that shareholder and shall be signed by such shareholder
or by that shareholder's proxy.  Except as otherwise required by law or by
these bylaws all voting may be viva voce.

11. The Secretary or other officer in charge of the stock ledger of the
Company shall prepare and make at least ten days before every meeting of
shareholders a complete list of the shareholders entitled to vote at the
meeting arranged in alphabetical order and showing the address of each
shareholder and the number of shares registered in the name of each
shareholder.  Such list shall be open to the examination of any shareholder
for any purpose germane to the meeting during ordinary business hours for a
period of at least ten days prior to the meeting either at a place within
the city where the meeting is to be held, which place shall be specified in
the notice of the meeting, or if not so specified at the place where the
meeting is to be held.  The list shall also be produced and kept at the time
and place of the meeting during the whole time thereof and may be inspected
by any shareholder who is present.  The stock ledger shall be the only
evidence as to who are the shareholders entitled to examine the stock
ledger, the list required by this bylaw, or the books of the Company or to
vote in person or by proxy at any meeting of shareholders.

12. The Board of Directors shall present at each annual meeting, and when
called for by vote of the shareholders at any special meeting of the
shareholders, a full and clear statement of the business and condition of
the Company.

13. At all elections of directors and when otherwise required by law, the
chairman of the meeting shall appoint two inspectors of election.  The
inspectors shall be responsible for receiving, tabulating and reporting the
result of the votes taken.  No director or candidate for the office of
director shall be appointed such inspector.  The chairman of the meeting shall
open and close the polls.


                                  E-2-7

<PAGE>




 DIRECTORS.


14. The property, business and affairs of the Company shall be managed by
or under the direction of the Board of Directors, which may exercise all
such powers of the Company and do all such lawful acts and things as are
not by statute or by the Certificate of Incorporation or by these bylaws
directed or required to be exercised or done by the shareholders.

15. (a) The Board of Directors shall consist of twelve directors.  Directors
need not be shareholders.  The number of directors may be determined by a
majority vote of the entire Board of Directors.

(b) Except as otherwise provided by the Certificate of Incorporation, by
these bylaws or by law, at each meeting of the shareholders for the election
of directors at which a quorum shall be present, the persons receiving a
plurality of the votes cast shall be directors.  Such election shall be by
ballot.

(c) The directors, other than those who may be elected by the holders of any
class or series of stock having a preference over the Common Stock as to
dividends or upon liquidation, shall be classified, with respect to the time
for which they severally hold office, into three classes, as nearly equal in
number as possible, as determined by the Board of Directors, one class to be
originally elected for a term expiring at the annual meeting of stockholders
to be held in 1985, another class to be originally elected for a term expiring
at the annual meeting of stockholders to be held in 1986, and another class
to be originally elected for a term expiring at the annual meeting of
stockholders to be held in 1987, with the directors of each class to hold
office until their successors are elected and qualified.  At each annual
meeting of the stockholders, the successors of the class of directors whose
term expires at that meeting shall be elected to hold office for a term
expiring at the annual meeting of stockholders held in the third year
following the year of their election.  No decrease in the number of directors
constituting the Board of Directors or change in the restrictions and
qualifications for directors shall shorten the term of any incumbent director.

(d) Except as otherwise provided in the Certificate of Incorporation or in
these bylaws, each director shall continue in office until the expiration of
his term of office and until a successor shall have been elected and shall
have qualified, or until the director shall have resigned, or, in the case of
a director who is an employee of the Company, until the director shall have
resigned from employment with the Company or the director's employment shall
have been terminated by the Company.  In addition, a director who is not an
employee of the Company or who is the Chief Executive Officer of the Company
or a retired Chief Executive Officer of the Company shall retire from the
position of director at the Annual Meeting following attainment of age 70; an
employee who is a director of the Company (other than the Chief Executive
Officer or a retired Chief Executive Officer) shall retire from the position
of director on the effective date of the director's retirement as an employee
of the Company.  Any director of the Company may resign at any time by giving
written notice to the Chairman of the Board or to the Secretary of the Company.
Such resignation shall take effect at the time specified therein; and, unless
otherwise specified therein, the acceptance of such resignation shall not be
necessary to make it effective.  Exceptions to the requirements for the
retirement of a director may be made by the Board of Directors.

(e) Subject to the rights under Article FOURTH of the Certificate of
Incorporation of any class or series of stock having a preference over the
Common Stock as to dividends or upon liquidation to elect directors under
specified circumstances, any director or entire class of directors or the
entire Board of Directors may be removed from office, with or without cause,
only by the affirmative

                                  E-2-8

<PAGE>


vote of the holders of at least 75% of the outstanding shares of stock of
the Company entitled to vote generally in the election of directors, voting
together as a single class.

(f) Subject to the rights under Article FOURTH of the Certificate of
Incorporation of the Company of the holders of any class or series of stock
having a preference over the Common Stock as to dividends or upon liquidation
to elect directors under specified circumstances, newly created directorships
resulting from any increase in the number of directors and any vacancies on
the Board of Directors resulting from death, resignation, retirement,
disqualification, removal or other cause shall be filled only by the
affirmative vote of a majority of the remaining directors then in office,
even though less than a quorum of the Board of Directors.  Any director elected
in accordance with the preceding sentence shall hold office for the remainder
of the full term of the class of directors in which the new directorship was
created or the vacancy occurred and until such director's successor shall have
been elected and qualified.


16. The directors may hold their meetings and keep the books of the Company
at such place or places as they may from time to time determine.

17. Regular meetings of the Board of Directors may be held at such time as
may be fixed from time to time by resolution of the Board of Directors.
Unless required by said resolution, notice of any such meeting need not be
given.

18. Special meetings of the Board of Directors shall be held whenever called
by direction of the Chairman of the Board or any of three of the directors
for the time being in office.  Notice of each such special meeting shall be
mailed, postage prepaid, to each director, addressed to the director at the
director's residence or usual place of business, at least two days before
the day on which the meeting is to be held, or shall be sent to the director
at such place by telegraph, cable, or wireless, or be delivered personally
or by telephone, not later than the day before the day on which the meeting
is to be held.  Every such notice shall state the time and place but, except
as provided by these bylaws or by resolution of the Board of Directors, need
not state the purposes of the meetings.

19. Anything in these bylaws or in any resolution adopted by the Board of
Directors to the contrary notwithstanding, notice of any meeting of the
Board of Directors need not be given to any director, if, before or after
any such meeting, notice thereof shall be waived by such director in writing
or by telegraph, cable or wireless.  Any meeting of the Board of Directors
shall be a legal meeting without any notice having been given or regardless
of the giving of any notice or the adoption of any resolution in reference
thereto, if all the directors shall be present thereat or shall have so
waived notice thereof.  Any action required or permitted to be taken at any
meeting of the Board of Directors may be taken without a meeting, if prior
to such action a written consent thereto is signed by all members of the
Board and such written consent is filed with the minutes of proceedings of
the Board of Directors.

20. Five of the directors in office at the time of any regular or special
meeting of the Board of Directors shall constitute a quorum for the
transaction of business at such meeting and except as may be otherwise
specifically provided by statute or by the Certificate of Incorporation or by
these bylaws, the act of a majority of the directors present at any such
meeting at which a quorum is present shall be the act of the Board of
Directors.  In the absence of a quorum a majority of the directors present
may adjourn any meeting from time to time until a quorum is present.  Notice
of any adjourned meeting need not be given.  The directors shall act only as
a board and the individual directors shall have no power as such.




                                E-2-9

<PAGE>


21. At each meeting of the Board of Directors the Chairman of the Board
shall preside.  The Chairman of the Board may designate another member of
the Board of Directors to preside as chairman of a meeting in place of the
Chairman of the Board and in the absence of the Chairman of the Board and
any member of the Board of Directors designated by the Chairman of the Board
to preside as chairman of the meeting a majority of the directors present
may designate a member of the Board of Directors as chairman to preside at
the meeting.  The Secretary of the Company or, in the absence of the
Secretary, a person appointed by the chairman of the meeting, shall act as
secretary of the Board of Directors.  The Board of Directors may adopt such
rules and regulations for the conduct of their meetings and the management of
the affairs of the Company as they shall deem proper and not inconsistent
with the law or with these bylaws.  At all meetings of the Board of Directors
business shall be transacted in such order as the Board of Directors may
determine.

22. Each director shall be paid such fee, if any, for each meeting of the
Board attended and/or such annual fee as shall be determined from time to
time by resolution of the Board of Directors, provided that nothing herein
contained shall be construed to prevent any director from serving the Company
in any other capacity and receiving compensation therefor.

23. (a) Definitions.  As used herein, the term "director" shall include each
present and former director of the Company and the term "officer" shall
include each present and former officer of the Company as such, and the
terms "director" and "officer" shall also include each employee of the
Company, who, at the Company's request, is serving or may have served as a
director or officer of another corporation in which the Company owns directly
or indirectly, shares of capital stock or of which it is a creditor.  The
term "officer" also includes each assistant or divisional officer.  The term
"expenses" shall include, but not be limited to, reasonable amounts for
attorney's fees, costs, disbursements and other expenses and the amount or
amounts of judgments, fines, penalties and other liabilities.

(b) Indemnification Granted.  Each director and officer shall be and hereby
is indemnified by the Company, to the full extent permitted by law, against:

(i) expenses incurred or paid by the director or officer in connection with
any claim made against such director or officer, or any actual or threatened
action, suit or proceeding (civil, criminal, administrative, investigative or
other, including appeals and whether or not relating to a date prior to the
adoption of this bylaw) in which such director or officer may be involved as
a party or otherwise, by reason of being or having been a director or officer
of the Company, or of serving or having served at the request of the Company
as a director, officer, employee, or agent of another corporation,
partnership, joint venture, trust or other enterprise, or by reason of any
action taken or not taken by such director or officer in such capacity, and

(ii) the amount or amounts paid by the director or officer in settlement of
any such claim, action, suit or proceeding or any judgment or order entered
therein, however, notwithstanding anything to the contrary herein where a
director or officer seeks indemnification in connection with a proceeding
voluntarily initiated by such director or officer the right to indemnification
granted hereunder shall be limited to proceedings where such director or
officer has been wholly successful on the merits.





                                  E-2-10

<PAGE>


(c)Miscellaneous.

(i) Expenses incurred and amounts paid in settlement with respect to any
claim, action, suit or proceeding of the character described in
paragraph (b)(i) above may be advanced by the Company prior to the final
disposition thereof upon receipt of an undertaking by or on behalf of the
recipient to repay such amounts as shall not ultimately be determined to be
payable to such recipient under this bylaw.

(ii) The rights of indemnification herein provided for shall be severable,
shall not be exclusive of other rights to which any director or officer now
or hereafter may be entitled, shall continue as to a person who has ceased
to be an indemnified person and shall inure to the benefit of the heirs,
executors, administrators and other legal representatives of such a person.

(iii) The provisions of this bylaw shall be deemed to be a contract between
the Company and each director or officer who serves in such capacity at any
time while such bylaw is in effect.

(iv) The Board of Directors shall have power on behalf of the Company to
grant indemnification to any person other than a director or officer to such
extent as the Board in its discretion may from time to time determine.



COMMITTEES OF THE BOARD.


24. (a) The Board of Directors may, by resolution or resolutions, passed by a
majority of the whole Board of Directors, designate an Executive Committee
(and may discontinue the same at any time) to consist of three or more of the
Directors of the Company.  The members shall be appointed by the Board of
Directors and shall hold office during the pleasure of the Board of Directors;
provided, however, that in the absence or disqualification of any member of
the Executive Committee, the member or members thereof present at any meeting
and not disqualified from voting, whether or not the member or members
constitute a quorum, may unanimously appoint another member of the Board of
Directors to act at the meeting in the place of any such absent or
disqualified member.  The Executive Committee shall have and may exercise,
during the intervals between the meetings of the Board of Directors, all of
the powers of the Board of Directors in the management of the business and
affairs of the Company (and shall have power to authorize the seal of the
Company to be affixed to all papers which may require it), except that the
Executive Committee shall have no power to (i) elect Directors to fill any
vacancies or appoint any officers; (ii) fix the compensation of any officer
or the compensation of any Director for serving on the Board of Directors or
on any committee; (iii) declare any dividend or make any other distribution
to the shareholders of the Company; (iv) submit to shareholders any action
that needs shareholder authorization; (v) amend or repeal the bylaws or adopt
any new bylaw; (vi) amend or repeal any resolution of the Board of Directors
which by its terms shall not be so amendable or repealable; (vii) take any
final action with respect to the acquisition or disposition of any business
at a price in excess of $20,000,000.


(b) The Board of Directors shall, by resolution or resolutions, passed by a
majority of the whole Board of Directors designate an Audit Committee to
consist of three or more non-employee directors of


                                      E-2-11

<PAGE>


the Company free from any relationship that, in the opinion of the Board of
Directors, would interfere with the exercise of independent judgment as a
Committee member.   Any director who is a former employee of the Company may
not serve on the Audit Committee.  The members of the Audit Committee shall
be appointed by and hold office during the pleasure of the Board of Directors.
A majority of the members of the Audit Committee will constitute a quorum for
the transaction of business.  It shall be the duty of the Audit Committee
(i) to recommend to the Board of Directors a firm of independent accountants
to perform the examination of the annual financial statements of the Company;
(ii) to review with the independent accountants and with the Controller the
proposed scope of the annual audit, past audit experience, the Company's
internal audit program, recently completed internal audits and other matters
bearing upon the scope of the audit; (iii) to review with the independent
accountants and with the Controller significant matters revealed in the
course of the audit of the annual financial statements of the Company;
(iv) to review on a biennial basis that the Company's Standards of Business
Conduct  have been communicated by the Company to all key employees of the
Company and its subsidiaries throughout the world with a direction that all
such key employees certify that they have read, understand and are not aware
of any violation of the Standards of Business Conduct; (v) to review with
the Controller any suggestions and recommendations of the independent
accountants concerning the internal control standards and the accounting
procedures of the Company; (vi) to meet on a regular basis with a
representative or representatives of the Internal Audit Department of the
Company and to review the Internal Audit Department's Reports of Operations;
(vii) to report its activities and actions to the Board of Directors at
least once each fiscal year.

(c) The Board of Directors may, by resolution or resolutions passed by a
majority of the whole Board of Directors, designate such other committees
as may be deemed advisable (and may discontinue the same at any time), to
consist of two or more of the directors of the Company.  The members shall
be appointed by and shall hold office during the pleasure of the Board of
Directors, and the Board of Directors shall prescribe the name or names of
such committees, the number of their members and their duties and powers.

(d) Any action required or permitted to be taken at any meeting of any
committee may be taken without a meeting, if prior to such action a written
consent thereto is signed by all members of the committee and such written
consent is filed with the minutes of proceedings of the committee.

25. All committees shall keep written minutes of their proceedings and report
the same to the Board of Directors when required.


OFFICERS.

26. The officers of the Company shall be a Chairman of the Board, a Vice
Chairman of the Board, a President, two or more Vice Presidents (which shall
include Senior Vice President, Executive Vice President and other Vice
President titles), a Treasurer, a Secretary, a Controller, and such other
officers as may be appointed in accordance with these bylaws.  The Secretary
and Treasurer may be the same person, or a Vice President may hold at the
same time the office of Secretary, Treasurer, or Controller.

27. The officers of the Company shall be chosen by the Board of Directors.
Each officer shall hold office until a successor shall have been duly chosen
and shall have qualified or until the death or retirement of the officer or
until the officer shall resign or shall have been removed in the manner
hereinafter provided.  The Chairman of the Board and the Vice Chairman of the
Board shall be chosen from among the directors.

                                  E-2-12

<PAGE>


28. The Board of Directors may appoint such other officers, committees or
agents, as the business of the Company may require, including one or more
Assistant Treasurers and one or more Assistant Secretaries, each of whom
shall hold office for such period, and have such authority and perform such
duties as are provided in these bylaws or as the Board of Directors may from
time to time determine.  The Board of Directors may delegate to any officer
or committee the power to appoint and to remove any such subordinate officer
or agent.

29. Subject to the provisions of any written agreement, any officer may be
removed, either with or without cause, by a vote of the majority of the whole
Board of Directors at a regular meeting or a special meeting called for the
purpose.  Any officer, except an officer elected by the Board of Directors,
may also be removed, with or without cause, by any committee or superior
officer upon whom such power of removal may be conferred by the Board of
Directors.

30. Subject to the provisions of any written agreement, any officer may
resign at any time by giving written notice to the Board of Directors, the
Chairman of the Board or the Secretary of the Company.  Any such resignation
shall take effect at the time specified therein; and, unless otherwise
specified therein, the acceptance of such resignation shall not be necessary
to make it effective.

31. Except as otherwise provided in these bylaws, in the event any officer
shall be unable to perform the duties of the office held, whether by reason
of absence, disability or otherwise, the Chairman of the Board may designate
another officer of the Company to assume the duties of the officer who is
unable to carry out the duties of the office; in the event the Chairman of
the Board shall be absent and unable to perform the duties of the office of
Chairman of the Board, the Chairman of the Board shall designate another
officer to assume the duties of the Chairman of the Board; if another officer
has not been designated by the Chairman of the Board to assume the duties of
the Chairman of the Board, then the Board of Directors shall designate
another officer to assume the duties of the Chairman of the Board; in the
event the Chairman of the Board shall be disabled and unable to perform the
duties of the office of Chairman of the Board, then the Board of Directors
shall designate another officer to assume the duties of the Chairman of the
Board.  Any officer designated to assume the duties of another officer shall
have all the powers of and be subject to all the restrictions imposed upon
the officer whose duties have been assumed.

32. A vacancy in any office because of death, resignation, removal,
disqualification or any other cause shall be filled for the unexpired portion
of the term in the manner prescribed by these bylaws for the regular
appointment or election to such office.

33. The Chairman of the Board shall be the chief executive officer of the
Company and shall have general supervision of the business and operations
of the Company, subject, however, to the control of the Board of Directors.
The Chairman of the Board shall preside at all meetings of the shareholders
and of the Board of Directors.  The Chairman of the Board shall perform all
of the duties usually incumbent upon a chief executive officer of a
corporation and incident to the office of the Chairman of the Board.  The
Chairman of the Board shall also have such powers and perform such duties
as are assigned by these bylaws and shall have such other powers and perform
such other duties, not inconsistent with these bylaws, as may from time to
time be assigned by the Board of Directors.

34. The Vice Chairman shall have such powers and perform such duties as are
assigned by these bylaws and shall have such other powers and perform such
other duties, not inconsistent with these bylaws, as from time to time may be
assigned by the Board of Directors or the Chairman of the Board.

35. The President shall have such powers and perform such duties as are
assigned by these bylaws and shall have such other powers and perform such
other duties, not inconsistent with these bylaws, as from time to time

                                E-2-13

<PAGE>


may be assigned by the Board of Directors or the Chairman of the Board.

36. Each Vice President shall have such powers and perform such duties as
are assigned by these bylaws and shall have such other powers and perform
such other duties, not inconsistent with these bylaws, as from time to time
may be assigned by the Board of Directors or the Chairman of the Board.


37. The Treasurer shall have charge and custody of, and be responsible for,
all funds of the Company.  The Treasurer shall regularly enter or cause to
be entered in books to be kept by the Treasurer or under the Treasurer's
direction for this purpose full and adequate account of all moneys received
or paid by the Treasurer for the account of the Company; the Treasurer shall
exhibit such books of account and records to any of the directors of the
Company at any time upon request at the office of the Company where such
books and records shall be kept and shall render a detailed statement of
these accounts and records to the Board of Directors as often as it shall
require the same.  The Treasurer shall also have such powers and perform such
duties as are assigned the Treasurer by these bylaws and shall have such
other powers and perform such other duties, not inconsistent with these bylaws,
as from time to time may be assigned by the Board of Directors.

38. It shall be the duty of the Secretary to act as Secretary of all meetings
of the Board of Directors and of the shareholders of the Company, and to keep
the minutes of all such meetings in the proper book or books to be provided
for that purpose; the Secretary shall see that all notices required to be
given by or for the Company or the Board of Directors or any committee are
duly given and served; the Secretary shall be custodian of the seal of the
Company and shall affix the seal, or cause it to be affixed, to all documents,
the execution of which on behalf of the Company, under its seal shall have
been duly authorized in accordance with the provisions of these bylaws.  The
Secretary shall have charge of the share records and also of the other books,
records, and papers of the Company relating to its organization and management
as a corporation and shall see that the reports, statements and other
documents required by law are properly kept and filed; and shall in general
perform all the duties usually incident to the office of Secretary.  The
Secretary shall also have such powers and perform such duties as are assigned
by these bylaws, and shall have such other powers and perform such other
duties, not inconsistent with these bylaws, as from time to time may be
assigned by the Board of Directors.

39. The Controller shall perform the usual duties pertaining to the office of
the Controller.  The Controller shall have charge of the supervision of the
accounting system of the Company, including the preparation and filing of
all reports required by law to be made to any public authorities and
officials, and shall also have such powers and perform such duties, not
inconsistent with these bylaws, as from time to time may be assigned by the
Board of Directors.

40. The Assistant Treasurers and the Assistant Secretaries shall have such
powers and perform such duties as are assigned to them by these bylaws and
shall have such other powers and perform such other duties, not inconsistent
with these bylaws, as from time to time may be assigned to them by the
Treasurer or the Secretary, respectively, or by the Board of Directors.

41. The compensation of the Chairman of the Board, Vice Chairman of the Board,
President, Vice President, Treasurer, Secretary and Controller shall be fixed
by the Board of Directors.  The compensation of such other officers as may be
appointed in accordance with the provisions of these bylaws may be fixed by
the Chairman of the Board.  No officer shall be prevented from receiving such
compensation by reason of also being a director of the Company.



                                    E-2-14

<PAGE>



CONTRACTS, CHECKS, DRAFTS, BANK ACCOUNTS, ETC.


42. The Board of Directors except as in these bylaws otherwise provided, may
authorize any officer or officers, agent or agents, in the name of and on
behalf of the Company, to enter into any contract or execute and deliver any
instrument, and such authority may be general or confined to specific
instances; and, unless so authorized by the Board of Directors or expressly
authorized by these bylaws, no officer or agent or employee shall have any
power or authority to bind the Company by any contract or engagement or to
pledge its credit or to render it pecuniarily liable for any purpose or to
any amount.

43. No loans shall be contracted on behalf of the Company and no negotiable
paper shall be issued in its name unless authorized by resolution of the
Board of Directors.  When authorized by the Board of Directors, any officer
or agent of the Company thereunto authorized may effect loans and advances at
any time for the Company from any bank, trust company, or other institution,
or from any firm, corporation or individual, and for such loans and advances
may make, execute and deliver promissory notes, bonds, or other certificates
or evidences of indebtedness of the Company and, when authorized so to do,
may pledge, hypothecate or transfer any securities or other property of the
Company as security for any such loans or advances.  Such authority may be
general or confined to specified instances.

44. All checks, drafts and other orders for the payment of moneys out of the
funds of the Company and all notes or other evidences of indebtedness of the
Company shall be signed on behalf of the Company in such manner as shall from
time to time be determined by resolution of the Board of Directors.

45. All funds of the Company not otherwise employed shall be deposited from
time to time to the credit of the Company in such banks, trust companies or
other depositories as the Board of Directors may select or as may be selected
by any officer or officers, agent or agents of the Company to whom such power
may from time to time be delegated by the Board of Directors; and for the
purpose of such deposit, the Chairman of the Board, the Vice Chairman of the
Board, the President, a Vice President, the Treasurer, the Controller, the
Secretary or any other officer or agent or employee of the Company to whom
such power may be delegated by the Board of Directors, may endorse, assign
and deliver checks, drafts and other orders for the payment of moneys which
are payable to the order of the Company.



CERTIFICATES AND TRANSFERS OF SHARES.


46. The shares of the Company shall be represented by certificates or shall
be uncertificated.  Each registered holder of shares, upon request to the
Company, shall be provided with a certificate of stock, representing the
number of shares owned by such holder.  Certificates for shares of the Company
shall be in such form as shall be approved by the Board of Directors. Such
certificates shall be numbered and registered in the order in which they are
issued and shall be signed by the  Chairman of the Board, the Vice Chairman
of the Board, the President or a Vice President and the Secretary or an
Assistant Secretary or the Treasurer or an Assistant Treasurer.  Where any
such certificate is countersigned by a transfer agent, other than the Company
or its employee, or by a registrar, other than the Company or its employee,
any other signature on such certificate may be a facsimile, engraved, stamped
or printed.  In the event that an officer whose facsimile signature appears
on such certificate ceases for any reason to hold the office indicated and
the Company or its transfer agent has on hand a supply of share certificates
bearing such officer's facsimile signature, such certificates may continue to
be issued and registered until such supply is exhausted.

47. Transfers of shares of the Company shall be made only on the books of the
Company by the holder thereof, or by the holder's attorney thereunto duly
authorized and on either the surrender of the certificate or certificates

                                      E-2-15

<PAGE>


for such shares properly endorsed or upon receipt of proper transfer
instructions from the registered owner of uncertificated shares.  Every
certificate surrendered to the Company shall be marked "Cancelled," with the
date of cancellation, and no new certificate shall be issued in exchange
therefor until the old certificate has been surrendered and cancelled, except
as hereinafter provided.  Uncertificated shares shall be cancelled and
issuance of new equivalent uncertificated shares shall be made to the person
entitled thereto and the transaction shall be recorded upon the books of the
Company.

48. The holder of any shares of the Company shall immediately notify the
Company of any loss, destruction or mutilation of the certificate therefor
and the Company may issue a new certificate in the place of any certificate
theretofore issued by it alleged to have been lost, destroyed or mutilated.
The Board of Directors may, in its discretion, as conditions to the issue of
any such new certificate, require the owner of the lost or destroyed
certificate or the owner's legal representatives to make proof satisfactory
to the Board of Directors of the loss or destruction thereof and to give the
Company a bond in such form, in such sum and with such surety or sureties as
the Board of Directors may direct, to indemnify the Company against any claim
that may be made against it on account of any such certificate so alleged to
have been lost or destroyed.


DETERMINATION OF RECORD DATE.

49. In order that the Company may determine the shareholders entitled to
notice of or to vote at any meeting of shareholders or any adjournment thereof
or entitled to receive payment of any dividend or other distribution or
allotment of any rights or entitled to exercise any rights in respect of any
change, conversion or exchange of stock or for the purpose of any other lawful
action, the Board of Directors may fix in advance a record date which shall
not be more than 60 nor less than 10 days before the date of such meeting nor
more than 60 days prior to any other action.

If no record date is fixed:

(i) The record date for determining shareholders entitled to notice of or to
vote at a meeting of shareholders shall be at the close of business on the
day next preceding the day on which notice is given, or if notice is waived,
at the close of business on the day next preceding the day on which the
meeting is held.

(ii)  The record date for determining shareholders for any other purpose
shall be at the close of business on the day on which the Board of Directors
adopts the resolution relating thereto.

A determination of shareholders of record entitled to notice of or to vote
at a meeting of shareholders shall apply to any adjournment of the meeting
provided, however, that the Board of Directors may fix a new record date for
the adjourned meeting.



REGISTERED SHAREHOLDERS.


50. The Company shall be entitled to treat the holder of record of any share
or shares of stock as the holder in fact thereof and, accordingly, shall not
be bound to recognize any equitable or other claim to or interest in such
share on the part of any other person, whether or not it shall have express
or other notice thereof, save as expressly provided by the laws of Delaware.




                                    E-2-16

<PAGE>



FISCAL YEAR.


51. The fiscal year shall begin on the first day of January and end on the
thirty-first day of December in each year.



NOTICES.


52. Whenever under the provision of these bylaws notice is required to be
given to any director or shareholder, it shall be construed to mean personal
notice, but such notice may be given in writing, by mail, by depositing the
same in a post office or letter box, in a postpaid sealed wrapper, addressed
to such director or shareholder at such address as appears on the books of
the Company, or, in default of other address, to such director or shareholder,
at the General Post Office in the City of Wilmington, Delaware, and such
notice shall be deemed to be given at the time when the same shall be thus
mailed.

53. Any notice required to be given under these bylaws may be waived in
writing, signed by the person or persons entitled to said notice, whether
before or after the time stated therein.


AMENDMENTS.

54. Except as otherwise provided in the Certificate of Incorporation of the
Company and consistent therewith, these bylaws may be altered, amended or
repealed or new bylaws may be made by the affirmative vote of the holders
of record of a majority of the shares of the Company entitled to vote, at
any annual or special meeting, provided that such proposed action shall be
stated in the notice of such meeting, or, by a vote of the majority of the
whole Board of Directors, at any regular meeting without notice, or at any
special meeting provided that notice of such proposed action shall be stated
in the notice of such special meeting.














                                     E-2-17



                                                       EXHIBIT 21
                                                  -------------------
                   BRISTOL-MYERS SQUIBB COMPANY
                          SUBSIDIARY LIST

2309 Realty Corporation
3130827 CANADA INC.
345 Park Corporation
77 Wilson St., Corp.
A.G. Medical Services, P.A.
Alive & Well, Inc.
Allard Laboratories, Inc.
Allard Labs Acquisition LLC
Apothecon BV
Apothecon Farmaceutica Ltda.
Apothecon, Inc.
Apothecon, S.A.
Astel Laboratoires S.A.R.L.
B-MS Finance Limited
B-MS GeneRx
B-MSF SAS
B. L. Pharmaceuticals (Proprietary) Limited
Blisa Acquisition LLC
Blisa, Inc.
BMS Holdings
BMS Investco SAS
BMS Music Company
BMS-Generiques SA
BMSIC Pharma Handels GmbH & Co. KG
BMSIC Pharma-Handels Verwaltungs GmbH
Boclaro Inc.
Bristol (Iran) S.A.
Bristol Arzneimittel G.m.b.H.
Bristol Caribbean, Inc.
Bristol Foundation
Bristol Iran Private Company Limited
Bristol Laboratories Corporation
Bristol Laboratories Inc.
Bristol Laboratories International, S.A.
Bristol Laboratories Medical Information Systems Inc.
Bristol Pharmaceutical Information Center, S.A.
Bristol-Myers (Bangladesh) Inc.
Bristol-Myers (Japan) Limited
Bristol-Myers (Private) Limited
Bristol-Myers (Zaire) Ltd.

                                   E-3-1

<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

Bristol-Myers Award Superannuation Pty. Ltd.
Bristol-Myers Barceloneta, Inc.
Bristol-Myers Company Limited
Bristol-Myers de Mexico, S. de R. L. de C.V.
Bristol-Myers Ges.m.b.H.
Bristol-Myers International s.r.l.
Bristol-Myers Lion Ltd.
Bristol-Myers Middle East S.A.L.
Bristol-Myers Nederland Inc.
Bristol-Myers Oncology Therapeutic Network, Inc.
Bristol-Myers Overseas Corporation
Bristol-Myers Overseas Corporation (Guam Branch)
Bristol-Myers Overseas Corporation (Korea - Branch)
Bristol-Myers Pakistan (Pvt.) Limited
Bristol-Myers S.A.
Bristol-Myers Squibb (China) Investment Co., Ltd.
Bristol-Myers Squibb (Hong Kong) Limited
Bristol-Myers Squibb (Israel) Limited
Bristol-Myers Squibb (Malaysia) Sendirian Berhad
Bristol-Myers Squibb (N.Z.) Limited
Bristol-Myers Squibb (Phil.) Inc.
Bristol-Myers Squibb (Proprietary) Limited
Bristol-Myers Squibb (Russia)
Bristol-Myers Squibb (Singapore) Pte. Limited
Bristol-Myers Squibb (Taiwan) Ltd.
Bristol-Myers Squibb (Thailand) Ltd.
Bristol-Myers Squibb (West Indies) Ltd.
Bristol-Myers Squibb A.E.B.E.
Bristol-Myers Squibb A.G.
Bristol-Myers Squibb Aktiebolag
Bristol-Myers Squibb Argentina, S.A.
Bristol-Myers Squibb Asia/Pacific, Inc. (Singapore - Branch)
Bristol-Myers Squibb Auslandsbeteiligungs Holding, GmbH
Bristol-Myers Squibb Australia Pty. Ltd.
Bristol-Myers Squibb B.V.
Bristol-Myers Squibb Belgium, S.A.
Bristol-Myers Squibb Brasil, S.A.
Bristol-Myers Squibb Bulgaria EOOD
Bristol-Myers Squibb Business Services Limited
Bristol-Myers Squibb Canada Inc.
Bristol-Myers Squibb Caribbean Company
Bristol-Myers Squibb Caribbean Holdings, L.L.C.


                                   E-3-2

<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

Bristol-Myers Squibb de Colombia S.A.
Bristol-Myers Squibb de Costa Rica, S.A.
Bristol-Myers Squibb de Guatemala, S. A.
Bristol-Myers Squibb de Mexico, S de R.L. de C.V.
Bristol-Myers Squibb de Venezuela, S.A.
Bristol-Myers Squibb Delta Holdings, L.L.C.
Bristol-Myers Squibb Dominicana, S.A.
Bristol-Myers Squibb Ecuador C.A.
Bristol-Myers Squibb Europa PLC
Bristol-Myers Squibb Europe Headquarters SARL
Bristol-Myers Squibb Export SA
Bristol-Myers Squibb Farmaceutica Portuguesa Limitada
Bristol-Myers Squibb Foreign Sales Corporation
Bristol-Myers Squibb G.m.b.H.
Bristol-Myers Squibb Ges. m.b.H.
Bristol-Myers Squibb Global Properties Ltd.
Bristol-Myers Squibb Holding Germany GMBH
Bristol-Myers Squibb Holdings B.V.
Bristol-Myers Squibb Holdings Limited
Bristol-Myers Squibb Holdings Limited (Ireland - Branch)
Bristol-Myers Squibb Holdings Limited (Kenya - Branch)
Bristol-Myers Squibb Ilaclari Limited Sirketi
Bristol-Myers Squibb Ilaclari, Inc.
Bristol-Myers Squibb Ilaclari, Inc. (Turkey - Branch)
Bristol-Myers Squibb International Company
Bristol-Myers Squibb International Corporation
Bristol-Myers Squibb International Corporation (Belgium - Branch)
Bristol-Myers Squibb International Corporation (Egypt - Branch)
Bristol-Myers Squibb International Corporation (Spain - Branch)
Bristol-Myers Squibb International Insurance Company
Bristol-Myers Squibb International Limited
Bristol-Myers Squibb Investco, Inc.
Bristol-Myers Squibb K.K.
Bristol-Myers Squibb Korea Ltd.
Bristol-Myers Squibb Laboratories Company
Bristol-Myers Squibb Manufacturing
Bristol-Myers Squibb MEA S.A. (Saudi Arabia - Branch)
Bristol-Myers Squibb MEA S.A. (Switzerland)
Bristol-Myers Squibb MEA S.A.(Egypt - Branch)
Bristol-Myers Squibb Norway Ltd.
Bristol-Myers Squibb Pakistan (Pvt.) Ltd.
Bristol-Myers Squibb Peru S.A.


                                   E-3-3

<PAGE>

                 BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

Bristol-Myers Squibb Pharmaceuticals Limited (England)
Bristol-Myers Squibb Pharmaceuticals Limited (Ireland)
Bristol-Myers Squibb Products S.A.
Bristol-Myers Squibb Puerto Rico, Inc.
Bristol-Myers Squibb Research Foundation Africa
Bristol-Myers Squibb S.p.A.
Bristol-Myers Squibb Service Ltd.
Bristol-Myers Squibb Sp. z o.o.
Bristol-Myers Squibb Spol. s r.o.
Bristol-Myers Squibb Superannuation Plan Pty. Ltd.
Bristol-Myers Squibb Zentrum Fuer Forschung Und Fortbildung Im
     Gesundheitswesen G.m.b.H.
Bristol-Myers Squibb, S.A.
Bristol-Myers Zimmer Award Superannuation Plan
Cancer Research, Inc.
Carboplant Spezialimplante GmbH
CJG Partners, L.P.
Clairol (China) Ltd.
Clairol Brazil Ltda.
Clairol GmbH.
Clairol Incorporated
Clairol International S.r.l.
Clairol Limited
Comercializadora RPM, S. De R.L. De C.V.
Compania Bristol-Myers Squibb de Centro America (El Salvador Branch)
Compania Bristol-Myers Squibb de Centro America (Honduras Branch)
Compania Bristol-Myers Squibb de Centro America (Nicaragua Branch)
Compania Bristol-Myers Squibb de Centro America (Panama Branch)
Convatec Limited
Convatec Spot s r.o.
Convatec Vertriebs G.m.b.H.
Convatec, S.A.
CRBM GIE
Delmed S.A.
Dong-A-Biotech Co., Ltd.
Duart Industries, Ltd.
E. R. Squibb & Sons de Venezuela, C.A.
E. R. Squibb & Sons Inter-American (Chile - Branch)
E. R. Squibb & Sons Inter-American Corporation
E. R. Squibb & Sons Inter-American Corporation (Colombia - Branch)
E. R. Squibb & Sons Inter-American Corporation (PRico - Branch)
E. R. Squibb & Sons Limited


                                   E-3-4

<PAGE>

                 BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

E. R. Squibb & Sons, Inc.
E. R. Squibb & Sons, Inc. (England - Branch)*
Elektrochemische Ges.Hirschfelde M.b.H.
ESS Partners, L.P.
EWI Corporation
G.I.E. Centre de Recherche de Biologie Moleculaire
G.I.E. Institut de Recherche Squibb
Grove Insurance Company Ltd.
Grove Limited
Grove Products (Far East) Limited
Grove Products (Far East) Limited (India - Branch)
Heyden Farmaceutica Portugesa Limitada
Iris Acquisition Corp.
JG Partners, L.P.
Kingsdown Medical Consultants Limited
Laboratoire Oberlin
Laboratoires Convatec S.A.
Laboratoires Guieu France S.a.r.l.
Laboratoires UPSA, SAS
Lawrence Laboratories
Linson Investments Limited
Linson Pharma Inc.
Listo B.V.
Little Sycamore Limited
Logics International, Inc.
Matrix Essentials Itallia SRL
Matrix Essentials, Inc.
Mead Johnson & Company
Mead Johnson (Guangzhou) Ltd.
Mead Johnson (Manufacturing) Jamaica Limited
Mead Johnson A.E.B.E.
Mead Johnson B.V.
Mead Johnson de Mexico, S. de R.L. de C.V.
Mead Johnson Farmaceutica Limitada
Mead Johnson International Limited (Argentine - Branch)
Mead Johnson International Limited (Canada)
Mead Johnson International Limited (Colombia - Branch)
Mead Johnson Jamaica Ltd.
Mead Johnson Limited
Mead Johnson Nutritional GmbH
Mead Johnson Pharmaceutical, Inc.
Mead Johnson S.p.A.


                                   E-3-5
<PAGE>

                 BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

MEC Subsidiary Corporation
Medical Engineering Corporation
Monarch Crown Corporation
Oncogen Limited Partnership
Oncology Therapeutics Network Automated Technologies, Inc.
Oncology Therapeutics Network Corporation
Oncology Therapeutics Network Joint Venture, L.P.
Orthoplant Endoprothetik GmbH
Osmat S.A.
OTN Funding Corp.
OTN Online, Inc.
OTN Parent Corp.
Oy Bristol-Myers Squibb (Finland) AB
P. T. Squibb Indonesia
Pharmagen
Pharmavit Rt.
PRB Partners, L.P.
Princeton Pharmaceuticals, S.A.
Recherche et Propriete Industrielle
Redmond Products de Mexico, S. De R.L. De C.V.
Redmond Products Distributing, Inc.
Redmond Products International, Inc.
Redmond Products, Inc.
Route 22 Real Estate Holding Corporation
RPI Management, Inc.
S+G Implants G.m.b.H.
S.O.F.C.A.
Salorpharma G.m.b.H.
Sanofi Pharma Bristol-Myers Squibb SNC
Schuppert Meubelen Holten B.V.
Sino-American Shanghai Squibb Pharmaceuticals Limited
Societe Francaise de Complements Alimentaires
Squibb (Far East) Limited
Squibb (Far East) Limited (Taiwan - Branch)
Squibb (Nigeria) Limited
Squibb (Thailand) Limited
Squibb ApS
Squibb Convatec Medical Products Co. Ltd.
Squibb Development Limited
Squibb Farmaceutica Portuguesa, Limitada
Squibb Industria Farmaceutica, S.A.
Squibb Manufacturing, Inc.


                                   E-3-6

<PAGE>

                       BRISTOL-MYERS SQUIBB COMPANY
                              SUBSIDIARY LIST

Squibb Middle East S.A. (Egypt - Branch)
Squibb Middle East S.A. (Jordan - Branch)
Squibb Middle East S.A. (Panama)
Squibb Overseas Investments, Inc.
Squibb Pacific Limited
Squibb Pharma G.m.b.H.
Squibb Properties, Inc.
Squibb Surgicare Limited
Squibb-von Heyden G.m.b.H.
Stamford Holdings B.V.
Swords Holdings I, L.L.C.
Swords Holdings II, L.L.C.
Swords Laboratories
T S V Corporation
Tallosa, S.A.
The B-M Group (Proprietary) Limited
Unterstuetzungskasse Bristol-Myers Squibb G.m.b.H.
Upsamedica LDA
Upsamedica SA NV
Upsamedica SpA
Von Heyden Pharma G.m.b.H.
Wallingford Research, Inc.
Westwood-Intrafin, S.A.
Westwood-Squibb Holdings, Inc.
Westwood-Squibb Pharmaceuticals, Inc.
Zimmer B.V.
Zimmer Caribe, Inc.
Zimmer Chirurgie G.m.b.H.
Zimmer Europe Limited
Zimmer Limited
Zimmer New Zealand Limited
Zimmer of Canada Limited
Zimmer Pte. Ltd.
Zimmer S. A. S.(France)
Zimmer S.A. (Spain)
Zimmer S.R.L.
Zimmer SAS
Zimmer, Inc.




                                   E-3-7






                                                            Exhibit 23
                                                           ------------


                   CONSENT OF INDEPENDENT ACCOUNTANTS
 ---------------------------------------------------------------------






We hereby consent to the incorporation by reference in the Registration
Statements on Form S-8 (Nos. 33-30856, 33-38411, 33-38587,  33-44788,
333-47403,   33-52691,   33-58187  and   333-02873),   Post-Effective
Amendment  No. 2 on Form S-8 (No. 33-30756-02) to Form S-4 (No.  333-
09519),  Form  S-3  (Nos. 33-33682 and 333-49227)  and  Pre-Effective
Amendment  No.  1 on Form S-3 (No. 33-62496) of Bristol-Myers  Squibb
Company  of  our  report  dated January  24,  2000  relating  to  the
financial  statements  and  the financial statement  schedule,  which
appears in this Form 10-K.


/s/ PricewaterhouseCoopers LLP
- --------------------------------------------


PRICEWATERHOUSECOOPERS LLP
New York, New York
March 30, 2000

                                E-4-1


<TABLE> <S> <C>

<ARTICLE> 5
<MULTIPLIER> 1,000,000

<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-END>                               DEC-31-1999
<CASH>                                            2720
<SECURITIES>                                       237
<RECEIVABLES>                                     3440
<ALLOWANCES>                                       168
<INVENTORY>                                       2126
<CURRENT-ASSETS>                                  9267
<PP&E>                                            7841
<DEPRECIATION>                                    3220
<TOTAL-ASSETS>                                   17114
<CURRENT-LIABILITIES>                             5537
<BONDS>                                           1342
                                0
                                          0
<COMMON>                                           219
<OTHER-SE>                                        8426
<TOTAL-LIABILITY-AND-EQUITY>                     17114
<SALES>                                          20222
<TOTAL-REVENUES>                                 20222
<CGS>                                             5539
<TOTAL-COSTS>                                     5539
<OTHER-EXPENSES>                                  4252
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                 130
<INCOME-PRETAX>                                   5767
<INCOME-TAX>                                      1600
<INCOME-CONTINUING>                               4167
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                      4167
<EPS-BASIC>                                     2.10
<EPS-DILUTED>                                     2.06



</TABLE>

                                                          EXHIBIT 99.1
                                                     -------------------

CAUTIONARY   STATEMENT   PURSUANT   TO   PRIVATE   SECURITIES
LITIGATION  REFORM  ACT OF 1995 - "SAFE HARBOR"  FOR  FORWARD
LOOKING STATEMENTS.

The  Company  is  hereby filing a cautionary statement  identifying
important factors that could cause the Company's actual results  to
differ   materially  from  those  projected  in   forward   looking
statements made by or on behalf of the Company.  There are  several
communications made by or on behalf of the Company (including,  but
not limited to, the Annual Report to Stockholders, Annual Report on
Form  10-K,  Quarterly  Reports on  Form  10-Q  and  other  filings
pursuant  to  the Securities Exchange Act of 1934, as amended,  and
any  other  public  statements made by the Company)  which  contain
statements  relating to goals, plans and projections regarding  its
financial  position,  results of operations,  market  position  and
product development, among other things, which are based on current
expectations   that   involve  inherit  risks  and   uncertainties,
including factors  that could delay, divert or change any  of  them
in the next several years.

These important factors include -

  New  government  laws and regulations,  such  as  (i)  health
  care   initiatives,  (ii)  changes  in  the   FDA   and   foreign
  regulatory   approval  processes  which  may  cause   delays   in
  approving  new  products,  and (iii)  tax  changes  such  as  the
  phasing  out  of  tax  benefits  heretofore  available   in   the
  United States and certain foreign countries.

  Difficulties  in  developing  new  products;  new   products
  developed  by  competitors which have lower  prices  or  superior
  performance  features  or  which are otherwise  competitive  with
  the  Company's  current  products;  and  generic  competition  as
  the  Company's  products  lose  patent  protection,  as  well  as
  possible issues with licensors.

  Legal   difficulties  including  negative  results  relating
  to   patents;  adverse  decisions  in  litigation  including  the
  breast  implant  cases  and other product  liability  cases;  the
  inability  to  obtain  adequate insurance with  respect  to  this
  type  of  liability;  and recalls of pharmaceutical  products  or
  forced closing of manufacturing plants.

  Increasing  pricing  pressures worldwide  from  managed  care
  buyers   and  institutional  and  governmental  purchasers;   and
  changes  of  business  and  economic  conditions  including,  but
  not  limited  to,  changes in interest rates and  fluctuation  of
  foreign currency exchange rates.

No  assurance  can  be given that any goal or plan  set  forth  in
forward  looking  statements  can  be  achieved  and  readers   are
cautioned  not  to  place undue reliance on such statements,  which
speak  only  as  of  the  date  made.  The  Company  undertakes  no
obligation  to  release publicly any revisions to  forward  looking
statements as a result of future events or developments.

                          E-6-1




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