<PAGE> 1
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. )*
BIOCRYST PHARMACEUTICALS, INC.
(Name of Issuer)
COMMON STOCK
(Title of Class of Securities)
09058V 10 3
(CUSIP Number)
October 21, 1998
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[ ] Rule 13d-1(b)
[X] Rule 13d-1(c)
[ ] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
Page 1 of 7 Pages
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SCHEDULE 13G
CUSIP NO. 09058V 10 3 PAGE 2 OF 7 PAGES
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Johnson & Johnson 22-1024240
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)
[ ]
(b)
[ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
New Jersey
- --------------------------------------------------------------------------------
NUMBER OF 5 SOLE VOTING POWER
SHARES
BENEFICIALLY -0-
OWNED BY
EACH ------------------------------------------------------------
REPORTING 6 SHARED VOTING POWER
PERSON
WITH 918,836
------------------------------------------------------------
7 SOLE DISPOSITIVE POWER
-0-
------------------------------------------------------------
8 SHARED DISPOSITIVE POWER
918,836
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
918,836
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.17%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
CO
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
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SCHEDULE 13G
CUSIP NO. 09058V 10 3 PAGE 3 OF 7 PAGES
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Johnson & Johnson Development Corporation 22-2007137
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)
[ ]
(b)
[ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
New Jersey
- --------------------------------------------------------------------------------
NUMBER OF 5 SOLE VOTING POWER
SHARES
BENEFICIALLY -0-
OWNED BY
EACH ------------------------------------------------------------
REPORTING 6 SHARED VOTING POWER
PERSON
WITH 918,836
------------------------------------------------------------
7 SOLE DISPOSITIVE POWER
-0-
------------------------------------------------------------
8 SHARED DISPOSITIVE POWER
918,836
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
918,836
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.17%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
CO
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
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CUSIP 09058V 10 3 Page 4 of 7 Pages
Item 1. Name and Address of Issuer:
Biocryst Pharmaceuticals, Inc.
2190 Parkway Lake Drive
Birmingham, Alabama 35244
Item 2. (a) Name of Person Filing:
Johnson & Johnson ("J&J")
Johnson & Johnson Development corporation ("JJDC")
(b) Address of Principal Business Office of J&J and JJDC:
One Johnson & Johnson Plaza, New Brunswick, New
Jersey 08933
(c) Place of Organization or Citizenship:
J&J and JJDC are both New Jersey corporations
(d) Title of Class of Securities:
Common Stock, par value $.01
(e) CUSIP Number:
09058V 10 3
Item 3. This statement is filed pursuant to Rule 13d-1(c) by J&J and
JJDC.
Item 4. Ownership:
(a) Amount Beneficially Owned by J&J and JJDC
J&J 918,836
JJDC 918,836
(b) Percent of Class:
J&J 6.17%
JJDC 6.17%
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CUSIP 09058V 10 3 Page 5 of 7 Pages
(c) Number of Shares as to which the filing person has:
(i) sole power to vote or to direct the vote
J&J 0
JJDC 0
(ii) shared power to vote or to direct the vote
J&J 918,836
JJDC 918,836
(iii) sole power to dispose or to direct the disposition of
J&J 0
JJDC 0
(iv) shared power to dispose or to direct the disposition
of
JJDC 918,836
J&J 918,836
Item 5. Ownership of Five Percent or Less of a Class:
Not applicable
Item 6. Ownership of More Than Five Percent on Behalf of Another
Person:
Not applicable
Item 7. Identification and Classification of Subsidiaries which
Acquired the Security Being Reported on by the Parent Holding
Company:
Not applicable
Item 8. Identification and Classification of Members of the Group:
Not applicable
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CUSIP 09058V 10 3 Page 6 of 7 Pages
Item 9. Notice of Dissolution of Group:
Not applicable
Item 10. Certification:
By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were not acquired
and are not held for the purpose of or with the effect of
changing or influencing the control of the issuer of the
securities and were not acquired and are not held in
connection with or as a participant in any transaction having
that purpose or effect.
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CUSIP 09058V 10 3 Page 7 of 7 Pages
SIGNATURE
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.
JOHNSON & JOHNSON
By: /s/Peter S. Galloway
Name: Peter S. Galloway
Title: Secretary
Dated: October 27, 1998
JOHNSON & JOHNSON DEVELOPMENT
CORPORATION
By: /s/Peter S. Galloway
Name: Peter S. Galloway
Title: Secretary
Dated: October 27, 1998