JOHNSON & JOHNSON
8-K, 1999-12-14
PHARMACEUTICAL PREPARATIONS
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1




               SECURITIES AND EXCHANGE COMMISSION
                     Washington, D.C. 20549


                            FORM 8-K

       Current Report Pursuant to Section 13 or 15(d) of
              The Securities Exchange Act of 1934



Date of Report (Date of earliest event reported): October 6, 1999


                        JOHNSON & JOHNSON

     (Exact name of registrant as specified in its charter)


    New Jersey                         1-3215                  22-
1024240

  (State or other                  (Commission         (I.R.S.
Employer
  jurisdiction                     File Number)
Identification No.)
  of incorporation)



 One Johnson & Johnson Plaza, New Brunswick, New Jersey   08933

       (Address of principal executive offices)       (zip code)


Registrant's telephone number including area code: (732) 524-0400



Item 5.   Other Events.


As previously reported in Registrant's Form 10-Q  for the quarterly
period ended October 3, 1999,  on October 6, 1999,  Johnson &
Johnson ("J&J")  and Centocor, Inc. ("Centocor") completed their
merger (the "Merger"), pursuant to which Centocor merged with and
into a wholly owned subsidiary of J&J.  In connection with the
Merger, J&J is filing herewith certain supplemental financial
information, including the restated audited consolidated financial
statements of J&J and its subsidiaries as of  January 3, 1999 and
December 27, 1997 and for each of the years in the three-year
period ended January 3, 1999, together with the related
Management's Discussion and Analysis of Financial Condition and
Results of Operations of J&J, which are being filed as Exhibit 99.2
to this Form 8-K and are incorporated herein by reference. Also
incorporated herein by reference is the independent auditors'
report filed as Exhibit 99.1 herewith.

The supplemental financial statements give retroactive effect to
the Merger, which has been accounted for as a pooling of interests
as described in Note 1 to the supplemental consolidated financial
statements. Generally accepted accounting principles do not permit
giving effect to a consummated business combination accounted for
by the pooling of interests method in financial statements that do
not include the date of consummation. The supplemental financial
statements do not extend through the date of consummation. However,
they will become the historical consolidated financial statements
of J&J after financial statements covering the date of consummation
of the Merger are issued.

The unaudited supplemental condensed consolidated financial
statements of J&J and its subsidiaries for the three months and
nine months ended October 3, 1999, including the related
Management's Discussion and Analysis of Financial Condition and
Results of Operations of J&J, are being filed as Exhibit 99.2 to
this Form 8-K and are incorporated herein by reference.



Item 7.         Financial  Statements, Pro Forma Financial Information
          and Exhibits.

(c)  Exhibits



Exhibit No.                                  Description of Exhibit
99.1 Form 10K for the period ended January 3, 1999
27.1                          Financial Data Schedule as of January
3, 1999
99.2 Form 10Q for the period ended October 3, 1999
27.2                          Financial Data Schedule as of October
3, 1999
23                            Consent of Independent Accountants


                              SIGNATURE



Pursuant  to the requirements of the Securities  Exchange
Act  of  1934, the registrant has duly caused this report
to  be  signed on its behalf by the undersigned  hereunto
duly authorized.



                                   JOHNSON & JOHNSON




Date: December 13, 1999                 By: /s/ Clarence
E. Lockett
                                        Clarence E.
Lockett
                                   Controller




1

Overview
Record 1998 sales of $24.0 billion, an increase over 1997 of 5.1%, marked
the sixty-sixth consecutive year of positive sales growth.  The Company
achieved this increase despite the impact of the stronger dollar that
depressed sales by 2.5%.  During 1998, the Company completed the
acquisition of DePuy, Inc. and approved a reconfiguration plan for its
manufacturing facilities worldwide.  As a result, net earnings include a
special charge of $697 million for the cost of purchased in-process
research and development (IPR&D) related to acquisitions as well as
restructuring costs related to the reconfiguration plan.   The objective
of the reconfiguration plan was to enhance worldwide operating
efficiencies.  For detailed discussion of this plan and IPR&D, see Notes
15 and 17. Reported net earnings decreased by 9.3% to $3.0 billion.
Prior to the effect of the special charges, net earnings increased 11.7%
over 1997 and the net income margin for 1998 was a record high of 15.4%.
     The Company's investment in research and development continues to
drive sales of innovative products.  In 1998, $2.34 billion or 9.7% of
sales was invested in research and development.   This level of
investment, the highest in the Company's history, reflects the Company's
continued commitment in achieving significant advances in health care
through the discovery and development of innovative, knowledge based,
cost effective products that prolong and enhance the quality of life.
     In 1998, the Company continued to improve operating margins.  The
gross profit margin, excluding special charges, improved from 68.3% to
68.6% while selling, marketing and administrative expenses as a percent
to sales dropped from 38.4% to 37.6%.
     Cash from operations in 1998 was $4.90 billion and served as the
primary source of funding to finance the capital investments of $1.55
billion, dividend distribution of $1.31 billion and the purchase of
treasury stock of $0.9 billion with the remaining cash used to partially
fund the DePuy acquisition.  Cash dividends paid to shareowners in 1998
increased by 14.1% over 1997 and represented the thirty-sixth consecutive
year of dividend increases.
     Total equity market capitalization was $116.6 billion or an increase
of 29.3% over 1997 while the percentage return on average shareowners'
equity, excluding the impact of special charges, was 26.8% in 1998.
     The worldwide health care market continues to be transformed as
customers have become more knowledgeable and demand even greater value.
Simultaneously, the market place has become increasingly more
competitive.  The Company believes that it is well positioned to meet
these challenges by providing innovative products as demonstrated by the
Company's commitment to research and development.  In addition, dedicated
employees along with strong Credo values and decentralized management
structure enable the Company to provide its customers with value
creating, innovative products and services.

Sales and Earnings
     In 1998, worldwide sales increased 5.1% to $24.0 billion compared to
increases of 4.9% in 1997 and 15.0% in 1996.  Excluding the impact of
foreign currencies, worldwide sales increased 7.6% in 1998, 8.9% in 1997
and 16.8% in 1996.
     Worldwide net earnings for 1998 including the impact of the
Restructuring and In-Process Research and Development charge were $3.0
billion, reflecting an 9.3% decrease over 1997.  Worldwide net earnings
per share for 1998 equaled $2.12 per share, a decrease of 9.4% from the $
2.34 net earnings per share in 1997.
     Worldwide net earnings for 1998 excluding the impact of the
Restructuring and In-Process Research and Development charges were $3.7
billion, reflecting an 11.7% increase over 1997.  Excluding the impact of
these charges, worldwide net earnings per share for 1998 equaled $2.61
per share, an increase of 11.5% over the $2.34 net earnings per share in
1997.  The income margin for 1998, excluding the impact of these charges
was a record 15.4%, up from 14.5% in 1997.
     Worldwide net earnings for 1997 were $3.31 billion, or net earnings
per share of $2.34, representing an increase over 1996 of 14.1%. In 1996,
worldwide net earnings were $2.88 billion, or net earnings per share of
$2.05 on a split-adjusted basis, representing an increase over 1995 of
14.5%.
     Average diluted shares of common stock outstanding in 1998 and 1997
were 1.41 billion compared with 1.40 billion in 1996.
     Sales by domestic companies were $12.85 billion in 1998, $11.90
billion in 1997 and $10.99 billion in 1996.  This represents an increase
of 8.0% in 1998, 8.3% in 1997 and 19.0% in 1996.   The strong performance
of products introduced in the past few years and the continued expansion
of base businesses resulted in the sales increase in 1998.
     Sales by international companies were $11.15 billion in 1998, $10.94
billion in 1997 and $10.77 billion in 1996.  This represents an increase
of 1.9% in 1998, 1.5% in 1997 and 11.0% in 1996.  Excluding the impact of
the foreign currency fluctuations over the past three years,
international company sales increased 7.1% in 1998, 9.6% in 1997 and
14.5% in 1996.
     All geographic areas throughout the world posted solid operational
gains during 1998.  Excluding the effect of exchange rate fluctuations of
U.S. dollar on foreign currencies, sales increased 10.0% in Europe, 5.9%
in the Western Hemisphere (excluding the U.S.) and 8.8% in the Asia-
Pacific, Africa regions.
     The Company achieved an annual compound growth rate of 10.2% for
worldwide sales for the ten-year period since 1988 with domestic sales
growing at a rate of 10.8% and international sales growing at a rate of
9.7%.  For the same ten-year period, excluding the impact of special
charges in 1998, worldwide net earnings achieved an annual growth rate of
14.2%, while earnings per share grew at a rate of 14.1%.  For the last
five years, the annual compound growth rate for sales was 11.0%.
Excluding the special charges, the annual compound growth rate for net
earnings was 16.3% and the annual compound growth rate for earnings per
share was 15.0%.

Common Stock Market Prices
The Company's common stock is listed on the New York Stock Exchange under
the symbol JNJ.  The approximate number of shareowners of record at year-
end 1998 was 168,900.  The composite market price ranges for Johnson &
Johnson common stock during 1998 and 1997 were:
                              1998                                1997
                                 High       Low               High
                         Low

First quarter                                               76 1/2     63
3/8            62 _         48 5/8
Second quarter                                          77 7/8   67
66 7/8         51 1/8
Third quarter                                              80 _  68 1/4
65 7/8         55 1/8
Fourth quarter                                            89 _   72 5/8
67 5/16          52 5/8
Year-end close                         83 7/8                64 7/8

Cash Dividends Paid
The Company increased its dividends in 1998 for the thirty-sixth
consecutive year.  Cash dividends paid were $.97 per share in 1998
compared with dividends of $.85 per share in 1997 and $.735 per share in
1996.  The dividends were distributed as follows:
                              1998      1997      1996
First quarter                      $ .22          .19
 .165
Second quarter                   .25         .22                   .19
Third quarter                         .25         .22
 .19
Fourth quarter                        .25         .22
 .19
Total                              $. 97          .85
 .735

On December 3, 1998, the Board of Directors declared a regular cash
dividend of $.25 per share, paid on March 9, 1999 to shareowners of
record on February 11, 1999.
     The Company expects to continue the practice of paying regular cash
dividends.

Cost and Expenses
Research activities represent a significant part of the Company's
business.  These expenditures relate to the development of new products,
improvement of existing products, technical support of products and
compliance with governmental regulations for the protection of the
consumer.
Worldwide costs of research activities, excluding the write-off of IPR&D,
were as follows:

(Millions of Dollars)         1998      1997      1996
Research expense         $2,336               2,209               1,962
Percent increase over
   prior year               5.7%        12.6%              15.4%
Percent of sales            9.7           9.7                   9.0

Research expense as a percent of sales for the Pharmaceutical segment was
15.9% for 1998, 17.1% for 1997, and 15.7% for 1996 while averaging 6.1%,
5.7% and 5.6% in the other two segments.
     Advertising expenses, which are comprised of television, radio and
print media, were $1.19 billion in 1998, $1.26 billion in 1997 and 1996.
Additionally, significant expenditures were incurred for promotional
activities such as couponing and performance allowances.
     The Company believes that its operations comply in all material
respects with applicable environmental laws and regulations.  The Company
or its subsidiaries are parties to a number of proceedings brought under
the Comprehensive Environmental Response, Compensation, and Liability
Act, commonly known as Superfund, and comparable state laws, in which
primary relief sought is the cost of past and future remediation.  While
it is not feasible to predict or determine the outcome of these
proceedings, in the opinion of the Company, such proceedings would not
have a material adverse effect on the results of operations, cash flows
or financial position of the Company.
     Worldwide sales do not reflect any significant degree of
seasonality; however, spending has been heavier in the fourth quarter of
each year than in other quarters.  This reflects increased spending
decisions, principally for advertising and research grants.
     The worldwide effective income tax rate was 28.2% in 1998, 27.8% in
1997 and 28.3% in 1996.  The increase in the 1998 worldwide effective tax
rate was primarily due to the Company's charge for In-Process Research
and Development in 1998, primarily related to DePuy, which is not tax
deductible.  Refer to Note 6 of the Notes to Consolidated Financial
Statements for additional information.

Distribution of Sales Revenues
The distribution of sales revenues for 1998, 1997 and 1996 were:
                         1998           1997           1996
Employment costs              24.0%               23.9%
24.5%
Costs of materials
   and services                    48.9           50.8
51.9
Depreciation and
   amortization     of
   property and intangibles         5.4             4.7
4.7
Taxes other than payroll       6.3             6.1
5.7
Earnings reinvested
   in business                 7.1             9.5
8.7
Cash dividends paid            5.4             5.0
4.5
Restructuring/IPR&D            2.9                -
- -

Liquidity and Capital Resources
Cash generated from operations and selected borrowings provide the major
sources of funds for the growth of the business, including working
capital, additions to property, plant and equipment and acquisitions.
Cash and current marketable securities totaled $2.78 billion at the end
of 1998 as compared with $3.09 billion at the end of 1997.
     Total unused credit available to the Company approximates $3.2
billion, including $1.2 billion of credit commitments with various
worldwide banks, $0.8 billion of which expires on October 1, 1999 and
$0.4 billion on October 6, 2003.
     In 1998 the Company issued $60 million of 5.12% notes due 2003, the
proceeds of which were used for general corporate purposes.  Long-term
debt includes convertible subordinated debentures issued by Centocor in
1991 and 1998.  Debentures issued by Centocor in 1991 were fully retired
in April 1998.  Under the terms of the 4.75% Indenture issued in February
1998 due February 2005 and following the merger with Johnson & Johnson,
bondholders are entitled to convert their debentures into approximately
5,967,000 shares of Johnson & Johnson stock at a price of $77.091per
share.  After February 21, 2001 the debentures will be redeemable at the
option of the Company. The Company issued no medium term notes during
1998.  At January 3, 1999, the Company had $2.29 billion remaining on its
shelf registration of $2.59 billion.  A summary of borrowings can be
found in Note 4.
     Total borrowings at the end of 1998 and 1997 were $4.48 billion and
$1.90 billion, respectively.  The increase in borrowings was attributable
to financing the acquisition of DePuy and RETAVASE.  In 1998 net debt
(debt net of cash and current marketable securities) was 10.8% of net
capital (shareowners' equity and net debt). In 1997 net cash (cash and
current marketable securities net of debt) was $1.19 billion.  Total debt
represented 24.2% of total capital (shareowners' equity and total debt)
in 1998 and 12.9% of total capital in 1997.  Shareowners' equity per
share at the end of 1998 was $10.13 compared with $9.25 at year-end 1997,
an increase of 9.5%.  For the period ended January 3, 1999, there were no
material cash commitments.

Financial Instruments
The Company uses financial instruments to manage the impact of interest
rate and foreign exchange rate changes on earnings and cash flows.
Accordingly, the Company enters into forward foreign exchange contracts
to protect the value of existing foreign currency assets and liabilities
and to hedge future foreign currency product costs.  Gains or losses on
these contracts are offset by the gain or loss on the underlying
transaction.  A 10%  appreciation of the U.S. Dollar from January 3, 1999
market rates would increase the unrealized value of the Company's forward
contracts by $225 million.  Conversely, a 10.0% depreciation of the U.S.
Dollar from January 3, 1999 market rates would decrease the unrealized
value of the Company's forward contracts by $259 million.  In either
scenario, the gain or loss on the forward contract is offset by the gain
or loss on the underlying transaction and therefore has no impact on
future earnings and cash flows.
     The Company enters into interest rate and currency swap contracts to
manage the Company's exposure to interest rate changes and hedge foreign
currency denominated debt.  The impact of a 1% change in interest rates
on the Company's interest rate sensitive financial instruments is
immaterial.
     The Company does not enter into financial instruments for trading or
speculative purposes.  Further, the Company has a policy of only entering
into contracts with parties that have at least an "A" (or equivalent)
credit rating.  The counterparties to these contracts are major financial
institutions and the Company does not have significant exposure to any
one counterparty.  Management believes the risk of loss is remote and in
any event would be immaterial.

Changing Prices and Inflation
Johnson & Johnson is aware that its products are used in a setting where,
for more than a decade, policymakers, consumers, and businesses have
expressed concern about the rising cost of health care.  In response to
these concerns, Johnson & Johnson has a long standing policy of pricing
products responsibly.  For the period 1980-1998, in the United States,
the weighted average compound annual growth rate of Johnson & Johnson
price increases for health care products (prescription and over-the-
counter drugs, hospital and professional products) was below the U.S.
Consumer Price Index (CPI) for the period.
     Inflation rates, even though moderate in many parts of the world
during 1998, continue to have an effect on worldwide economies and,
consequently, on the way companies operate.  In the face of increasing
costs, the Company strives to maintain its profit margins through cost
reduction programs, productivity improvements and periodic price
increases.


YEAR 2000
  The "Year 2000" issue relates to potential problems resulting from a
practice of computer programmers.  For some time, calendar years have
frequently been represented in computer programs by their last two
digits.  Thus, "1998" would be rendered "98".  The logic of the programs
frequently assumes that the first two digits of a year given in this
format are "19".  It is unclear what would happen with respect to such
computer programs upon the change in calendar year from 1999 to 2000.
The program or device might interpret "00" as "2000", "1900", an error or
some other input.  In such a case, the computer program or device might
cease to function, function improperly, provide an erroneous result or
act in some unpredictable manner.
  The Company has had a program in place since the fourth quarter of 1996
to address Year 2000 issues in critical business areas related to its
products, information management systems, non-information systems with
embedded technology, suppliers and customers.  A report on the progress
of this program has been provided to the Audit Committee of the Company's
Board of Directors.  The Company has completed its review of its critical
automated information systems and the remediation phase with respect to
such critical systems is substantially complete.  Full completion is
expected during the fourth quarter of 1999.
   The Company is also in the process of reviewing and remediating, where
necessary,  its  other automated systems.  The Company has  substantially
completed  the  assessment and remediation of all  such  other  automated
systems  and  full  completion is expected during the fourth  quarter  of
1999.
   The  Company  has  a plan for assessment and testing  of  all  of  its
products  and  has  made substantial progress toward completion  of  such
assessment and testing.  All current products are Year 2000 ready.  There
are  a  few remaining units that require field updates at customer sites.
These updates will be completed during the fourth quarter of 1999.
   The  Company  has  engaged additional outside consultants  to  examine
selected  critical areas in certain of it major franchises.  In addition,
the  Company  has contracted with an independent third party  to  conduct
audits  of  critical sites worldwide to evaluate our programs,  processes
and  progress and to identify any remaining areas of effort  required  to
achieve compliance.
   The total costs of addressing the Company's Year 2000 readiness issues
are  not expected to be material to the Company's financial condition  or
results  of  operations.  Since initiation of its program  in  1996,  the
Company estimates that it has expensed approximately $125 million,  on  a
worldwide  basis,  in internal and external costs on a pre-tax  basis  to
address  its  Year  2000  readiness issues.  These  expenditures  include
information system replacement and embedded technology upgrade  costs  of
$111  million, supplier and customer compliance costs of $15 million  and
all  other costs of $69 million. The Company currently estimates that the
total of such costs for addressing its internal Year 2000 readiness, on a
worldwide basis, will approximate
$200 million in the aggregate on a pre-tax basis.  These costs are being
expensed as they are incurred and are being funded through operating cash
flows.  No projects material to the financial condition or results of
operations of the Company have been deferred or delayed as a result of
this project.
   The  ability  of  the Company to implement and effect  its  Year  2000
readiness   program  and  the  related  costs  or  the  costs   of   non-
implementation,  cannot  be  accurately determined  at  this  time.   The
Company's  automated  systems  (both  information  technology  and   non-
information systems) are generally complex but are decentralized.
   Although a failure to complete remediation of one system may adversely
affect  other systems, the Company does not currently believe  that  such
effects  are likely.  If, however, a significant number of such  failures
should occur, some of such systems might be rendered inoperable and would
require  manual  back-up methods or other alternatives, where  available.
In   such   a  case,  the  speed  of  processing  business  transactions,
manufacturing  and  otherwise conducting business would  likely  decrease
significantly  and  the cost of such activities would increase,  if  they
could be carried on at all.  That could have a material adverse effect on
the financial condition and results of operations of the business.
   The  Company has highly integrated relationships with certain  of  its
suppliers  and  customers.   These include  among  others:  providers  of
energy,  telecommunications, and raw materials and components,  financial
institutions, managed care organizations and large retail establishments.
The  Company  has  been  reviewing, and continues  to  review,  with  its
critical  suppliers  and major customers the status of  their  Year  2000
readiness.   The Company has in place a program of requesting  assurances
of  Year  2000  readiness  from such suppliers.  However,  many  critical
suppliers  have  either declined to provide the requested  assurances  or
have limited the scope of assurances to which they are willing to commit.
The Company has completed its plan for monitoring of critical suppliers.
   The Company has contacted major customers to assess their readiness to
deal  with  Year 2000 issues.  If a significant number of such  suppliers
and  customers  were to experience business disruptions as  a  result  of
their  lack of Year 2000 readiness, their problems could have a  material
adverse effect on the financial position and results of operations of the
Company.  This analysis of potential exposures includes both the domestic
and international operations of the Company.
   The  Company  believes  that its most reasonably  likely  "worst  case
scenario"  would  occur if a significant number of its key  suppliers  or
customers were not fully Year 2000 functional, in which case the  Company
estimates  that up to a 10 business day disruption in business operations
could  occur.   In  order  to  address this situation,  the  Company  has
formulated  contingency plans intended to deal with  the  impact  on  the
Company  of  Year 2000 problems that may be experienced by such  critical
suppliers and major customers.
   With  respect  to critical suppliers, these plans may  include,  among
others,  arranging  availability  of  substitute  sources  of  utilities,
closely   managing  appropriate  levels  of  inventory  and   identifying
alternate  sources  of  supply  of raw materials.  The  Company  is  also
alerting  customers  to  their need to address these  problems,  but  the
Company  has few alternatives available, other than reversion  to  manual
methods,  for  avoiding or mitigating the effects of lack  of  Year  2000
readiness by major customers.  In any  event, even where the Company  has
contingency plans, there can be no assurance that such plans will address
all   the  problems  that  may  arise,  or  that  such  plans,  even   if
implemented, will be successful.
   Notwithstanding  the foregoing, the Company has no reason  to  believe
that  its  exposure  to  the risks of supplier  and  customer  Year  2000
readiness is any greater than the exposure to such risk that affects  its
competitors  generally.  Further, the Company believes that its  programs
for  Year 2000 readiness will significantly improve its ability  to  deal
with  its  own  Year  2000 readiness issues and those  of  suppliers  and
customers over what would have occurred in the absence of such a program.
That does not, however, guarantee that some material adverse effects will
not occur.
  The descriptions of Year 2000 issues set forth in this section is
subject to the qualifications set forth herein under the heading
"Cautionary Factors that May Affect Future Results".

New Accounting Pronouncements
In June 1998, the Financial Accounting Standards Board issued Statement
of Financial Accounting Standards No. 133 "Accounting for Derivative
Instruments and Hedging Activities" (FAS 133).  This standard is
effective for all fiscal quarters of fiscal years beginning after June
15, 1999.  FAS 133 requires that all derivative instruments be recorded
on the balance sheet at their respective fair values.  Changes in the
fair value of derivatives are recorded each period in current earnings or
other comprehensive income, depending on the designation of the hedge
transaction.  For fair-value hedge transaction in which the Company is
hedging changes in an asset's, liability's or firm commitment's fair
value, changes in the fair value of the derivative instrument will
generally be offset by changes in the hedged item's fair value.  For cash
flow hedge transaction in which the Company is hedging the variability of
cash flows related to a variable rate asset, liability or forecasted
transaction, changes in the fair value of the derivative instrument will
be reported in other comprehensive income.  The gains and losses on the
derivative instrument that are reported in other comprehensive income
will be recognized in earnings in the periods in which earnings are
impacted by the variability of the cash flows of the hedged item.
  The Company will adopt FAS 133 in the first quarter of 2001 and does
not expect it to have a material effect on the Company's results of
operations, cash flows or financial position.

Segments of Business
Financial information for the Company's three worldwide business segments
is summarized below.  See Note 12 for additional information on segments
of business.

Sales                                        Increase
(Millions of Dollars)      1998      1997       Amount        Percent
Consumer            $  6,526         6,498             28              0.4%
Pharmaceutical          8,900        7,897       1,003               12.7%
Professional            8,569        8,435         134            1.6%
Worldwide total     $23,995        22,830       1,165             5.1%

Operating Profit                                         Percent of Sales
(Millions of Dollars)      1998           1998(1)  1997         1998
1997
Consumer            $   414             658        551          6.3%
8.5%
Pharmaceutical        2,933          3,132      2,572     33.0        32.6
Professional             941         1,409      1,543     11.0        18.3
Worldwide total     $4,288   5,199 4,666    17.9       20.4
Expenses not
   allocated to
   segments            (106)          (106)       (79)      (.4)      ( .3)
Earnings before taxes
   on income        $ 4,182           5,093     4,587     17.4%      20.1%

(1)  1998 results excluding Restructuring and In-Process Research and
  Development charges.
Excluding these charges, operating profits as a percent of sales by
segment was: Consumer
10.1%, Pharmaceutical 35.2% and Professional 16.4%
(2) Prior year restated to conform to 1998 presentation according to SFAS
No. 131.

Consumer
The Consumer segment's principal products are personal care and hygienic
products, including oral and baby care products, first aid products,
nonprescription drugs, sanitary protection products and adult skin and
hair care products.  Major brands include ACT Fluoride Rinse; BAND-AID
Brand Adhesive Bandages; CAREFREE Panty Shields; JOHNSON'S CLEAN & CLEAR
skin care products; IMODIUM A-D, an antidiarrheal; JOHNSON'S Baby line of
products; JOHNSON's pH 5.5 skin and hair care products; MONISTAT, a
remedy for vaginal yeast infections; MYLANTA gastrointestinal products
and PEPCID AC Acid Controller from the Johnson & Johnson  Merck Consumer
Pharmaceuticals Co.; NEUTROGENA skin and hair care products; NICOTROL
smoking cessation products; o.b. Tampons; PENATEN and NATUSAN baby care
products; PIZ BUIN and SUNDOWN sun care products; REACH toothbrushes; RoC
skin care products; SHOWER TO SHOWER personal care products; STAYFREE and
SURE & NATURAL sanitary protection products; and the broad family of
TYLENOL acetaminophen products.  These products are marketed principally
to the general public and distributed both to wholesalers and directly to
independent and chain retail outlets.
     Consumer segment sales in 1998 were $6.53 billion, an increase of
 .4% over 1997.  Domestic sales increased by 2.6% while international
sales declined by 1.7%.  International sales gains in local currency of
5.2% were offset by a negative currency impact of 6.9%.  Consumer sales
were led by continued strength in the skin care franchise that includes
the NEUTROGENA, RoC and CLEAN & CLEAR product lines, as well as strong
performances from the adult and children's MOTRIN line of analgesic
products.  During the fourth quarter, the Company announced the signing
of a definitive agreement to acquire the dermatological skin care
business of S.C. Johnson & Son, Inc., including the AVEENO brand
specialty soaps, bath, anti-itch and moisturizing cream and lotion
products.
     The 1998 special pre-tax charge for the Consumer segment was $244
million.  See Note 15 for detailed discussion on the Restructuring
charges.
     Consumer segment sales in 1997 were $6.50 billion, an increase of
2.1% over 1996.  Sales by domestic companies accounted for 49.9% of the
total segment, while international companies accounted for 50.1%.  During
1997, the Company announced a licensing agreement with Raisio Group of
Finland for the North American marketing rights (as well as a letter of
intent for the worldwide marketing rights) to a dietary ingredient,
stanol ester, which is patented for use in reducing cholesterol.  The
Company also established an alliance with Takeda Chemical Industries in
Japan for the sale and distribution of OTC products beginning with
several forms of TYLENOL brand acetaminophen products.
     Consumer segment sales in 1996 were $6.36 billion, an increase of
9.1% over 1995.  Sales by domestic companies accounted for 49.7% of the
total segment, while international companies accounted for 50.3%.  The
sales growth was led by the strong performance of TYLENOL brand products,
despite heavy competition.

Pharmaceutical
The Pharmaceutical segment represents over 50% of operating profit for
all segments.
     The Pharmaceutical segment's principal worldwide franchises are in
the allergy, anti-infective,  antifungal, antianemia, central nervous
system, contraceptive, dermatology, gastrointestinal, and pain management
fields.  These products are distributed both directly and through
wholesalers for use by health care professionals and the general public.
     Prescription drugs include DURAGESIC, (fentanyl transdermal system
sold abroad as DUROGESIC), a transdermal patch for chronic pain; EPREX
(Epoetin alfa sold in the U.S. as PROCRIT), a biotechnology derived
version of the human hormone erythropoietin that stimulates red blood
cell production; ERGAMISOL (levamisole hydrochloride), a colon cancer
drug; FLOXIN (ofloxacin) and LEVAQUIN (levofloxacin), both anti-
infectives; IMODIUM (loperamide HC1), an antidiarrheal; LEUSTATIN
(cladribine), for hairy cell leukemia; MOTILIUM (domperdone), a
gastrointestinal mobilizer; NIZORAL (ketoconazole), SPORANOX
(itraconazole) and TERAZOL (terconazole), antifungals; ORTHOCLONE OKT-3
(muromonab-CD3), for reversing the rejection of kidney, heart and liver
transplants, ORTHO-NOVUM (norethindrone/mestranol) group of oral
contraceptives; PREPULSID ( cisapride sold in the U.S. as PROPULSID), a
gastrointestinal prokinetic; REMICADE (infliximab), a novel monoclonal
antibody for treatment of certain Crohn's disease patients; RETAVASE
(reteplase), a recombinant biologic cardiology care product for the
treatment of acute myocardial infarction to improve blood flow to the
heart; RETIN-A (tretinoin), a dermatological cream for acne; RISPERDAL
(risperidone), an antipsychotic drug; and ULTRAM (tramadol
hydrochloride), a centrally acting prescription analgesic for moderate to
moderately severe pain.
     Johnson & Johnson markets more than 90 prescription drugs around the
world, with 43.9% of the sales generated outside the United States.
Twenty-nine drugs sold by the Company had 1998 sales in excess of $50
million, with 18 of them in excess of $100 million.
     Pharmaceutical segment sales in 1998 were $8.90 billion, an increase
of 12.7% over 1997 including 24.3% growth in domestic sales.
International sales increased .6% as sales gains in local currency of
5.4% were offset by a negative currency impact of 4.8%.  Worldwide growth
reflects the strong performance of RISPERDAL, PROCRIT, DURAGESIC,
LEVAQUIN, and the oral contraceptive line of products.  At year-end 1998,
the Company received approval from the FDA for LEVAQUIN (levocabastine)
for the indication of uncomplicated urinary tract infection.
Additionally, the Company completed the acquisition of the U.S. and
Canadian product rights for RETAVASE, an acute-care cardiovascular drug,
from Roche Healthcare.  RETAVASE is a recombinant biologic cardiology
care product administered for the treatment of acute myocardial
infarction (heart attack) to improve blood flow to the heart.
     The 1998 special pre-tax charge for the Pharmaceutical segment was
$65 million.  See Note 15 for detailed discussion on the Restructuring
and IPR&D charges.
     Pharmaceutical segment sales in 1997 were $7.90 billion, an increase
of 7.8% over 1996.  This growth reflects the strong performance of
RISPERDAL, PROCRIT, PROPULSID, ULTRAM, DURAGESIC, and LEVAQUIN, a new
anti-infective launched in 1997.  At year-end 1997, the Company received
approval from the FDA for REGRANEX (becaplermin), the first biologic
treatment proven to increase the incidence of healing in diabetic foot
ulcers.
     Pharmaceutical segment sales in 1996 were $7.32 billion, an increase
of 15.2% over 1995.  Domestic sales advanced 25.9% while international
sales advanced 7.2%.  The worldwide growth was a result of the
outstanding performances of PROCRIT, RISPERDAL, SPORANOX, PROPULSID,
ULTRAM, and DURAGESIC.
     Significant research activities continued in the Pharmaceutical
segment, increasing to $1.42 billion in 1998, or $66 million over 1997.
This represents 15.9% of 1998 Pharmaceutical sales and a compound annual
growth rate of approximately 13.6% for the five-year period since 1993.
     Pharmaceutical research is led by two worldwide organizations,
Janssen Research Foundation, headquartered in Belgium and the R.W.
Johnson Pharmaceutical Research Institute, headquartered in the United
States.  Additional research is conducted through collaboration with the
James Black Foundation in London, England.

Professional
The Professional segment includes suture and mechanical wound closure
products, minimally invasive surgical instruments, diagnostic products,
cardiology products, disposable contact lenses, surgical instruments,
orthopaedic joint replacement,  products for wound management and
infection prevention and other medical equipment and devices. These
products are used principally in the professional fields by physicians,
nurses, therapists, hospitals, diagnostic laboratories and clinics.
Distribution to these markets is done both directly and through surgical
supply and other dealers.
     Worldwide sales of $8.57 billion in the Professional segment
represented an increase of 1.6% over 1997.  Domestic sales were decreased
2.4% while international sales gains in local currency of 10.7% were
partially offset by the strength of the U.S. dollar.  Strong sales growth
from Ethicon Endo-Surgery's laparoscopy and mechanical closure products,
Ethicon's Mitek suture anchors and Gynecare's women's health products and
the acquisition of DePuy's orthopaedic products were offset by a decline
in sales of Cordis' coronary stents.
     During the fourth quarter, the Company completed the acquisition of
DePuy, one of the world's leading orthopaedic products companies with
products in reconstructive, spinal, trauma and sports medicine for $3.7
billion.  The Company also completed the acquisition of FemRx, a leader
in the development of proprietary surgical systems that enable surgeons
to perform less invasive alternatives to hysterectomy.
     At year-end 1998, two new Cordis products were approved for
marketing by the FDA. The S.M.A.R.T. stent, a self-expanding, crush-
recoverable nitinol stent was approved for use in treating biliary
obstructions.  Its nitinol alloy design allows for precise placement and
flexibility in reaching lesions, even through very tortuous vessels.  In
addition, the NINJA balloon was approved in the U.S. for use in
angioplasty procedures.
     The 1998 special pre-tax charge for the Professional segment for
restructuring was $304 million. See Notes 15 and 17 for detailed
discussion on Restructuring and IPR&D charges and Acquisitions.
     Worldwide sales of $8.44 billion in 1997 in the Professional segment
represented an increase of 4.5 % over 1996.  Sales growth continued to be
fueled by the excellent performance of Ethicon Endo-Surgery's minimally
invasive surgical instruments, Johnson & Johnson's orthopaedics business,
Vistakon's disposable contact lenses and LifeScan's blood glucose
monitoring systems.  The Asia-Pacific and Central Europe regions
contributed significantly to the overall increase in the Professional
segment.       There were also several business combinations in the
Professional segment during 1997.  These included Biopsys Medical, Inc.,
a maker of products for the diagnosis and management of breast cancer;
Biosense, Inc., a leader in medical sensor technology for use in
diagnostic and therapeutic interventional procedures; Gynecare, Inc., a
maker of minimally invasive medical devices for the treatment of uterine
disorders, and Innotech, Inc., a manufacturer of equipment for high
quality prescription eyeglass lenses.
     In 1996, Professional segment sales increased 19.8% over 1995, to
$8.07 billion.  The sales growth included the full year impact of the
merger with Cordis Corporation in early 1996.  Strong growth in the Asia-
Pacific region also contributed to the increase in the Professional
segment, as did excellent performances by LifeScan's blood glucose
monitors, Vistakon's disposable contact lenses, Ethicon Endo-Surgery's
minimally invasive surgical instruments and Johnson & Johnson
Professional's orthopaedic business.
     Acquisitions and divestitures during 1998 and 1997 are described in
more detail in Note 17.

Geographic Areas
The Company further categorizes its sales by major geographic area as
presented for the years 1998 and 1997:

Sales                                             Increase
(Millions of Dollars)      1998       1997        Amount         Percent
United States       $12,848        11,895           953             8.0%
Europe                  6,354        5,995          359             6.0
Western Hemisphere
   excluding U.S.       2,105        2,044            61             3.0
Asia-Pacific. Africa           2,688       2,896       (208)             (7.2)
Worldwide total     $23,995        22,830                    1,165
5.1%

International sales were once again negatively impacted by the
translation of local currency operating results into U.S dollars.
Average exchange rates to the dollar have declined each  year since 1995.
See Note 12 for additional information on geographic areas.

Description of Business
     The Company, which employs 94,300 employees worldwide, is engaged in
the manufacture and sale of a broad range of products in the health care
field. It conducts business in virtually all countries of the world.  The
Company's primary interest, both historically and currently, has been in
products related to health and well being.
     The Company is organized on the principle of decentralized
management.  The Executive Committee of Johnson & Johnson is the
principal management group responsible for the operations and allocation
of the resources of the Company.  In addition, several Executive
Committee members serve as Chairmen of Group Operating Committees, which
are comprised of managers who represent key operations within the group,
as well as management expertise in other specialized functions.  The
composition of these Committees can change over time in response to
business needs. These Committees oversee and coordinate the activities of
domestic and international companies related to each of the Consumer,
Pharmaceutical and Professional businesses. Operating management is
headed by a Chairman, President, General Manager or Managing Director who
reports directly, or through a line executive to a Group Operating
Committee.
     In line with this policy of decentralization,  each international
subsidiary is, with some exceptions, managed by citizens of the country
where it is located. The Company's international business is conducted by
subsidiaries manufacturing in 36 countries outside the United States and
selling in over 175 countries throughout the world.
     In all its product lines, the Company competes with companies both
large and small, located in the United States and abroad.  Competition is
strong in all lines without regard to the number and size of the
competing companies involved.  Competition in research, involving the
development and the improvement of new and existing products and
processes, is particularly significant and results from time to time in
product and process obsolescence.  The development of new and improved
products is important to the Company's success in all areas of its
business.  This competitive environment requires substantial investments
in continuing research and in multiple sales forces.  In addition, the
winning and retention of customer acceptance of the Company's consumer
products involves heavy expenditures for advertising, promotion, and
selling.

Five Year Summary:
(Dollars in millions except per share amounts)
                                   Fiscal Year Ended
                    Jan 1,  Dec 31,       Dec 29,       Dec 28, Jan 3,
*Jan 3,
                    1995    1995   1996   1997   1999   1999
EARNINGS DATA
Sales                $   15,801        18,921        21,755
22,830                  23,995          23,995
Cost and expenses         13,247       15,661        17,735
18,243                  19,813          18,902
Earnings before taxes               2,554              3,260
4,020                     4,587          4,182          5,093
Net earnings                1,923        2,367         2,881
3,311                     3,003           3,700

Earnings per diluted share    $      1.45               1.75
2.05                       2.34           2.12            2.61
Cash dividends per share            0.565               0.64
0.735                      0.85           0.97            0.97

BALANCE SHEET DATA
Assets                $ 16,201         18,379        20,603
22,108                  27,292          27,292
Long-term debt             2,431        2,339         1,465
1,181                    1,729            1,729
Shareowners' equity        7,356        9,260        11,324
12,866                  14,077          14,077

* Excludes IPR&D & Restructuring charges


Cautionary Factors That May Affect Future Results
This filing may contain forward-looking statements that anticipate
results based on management's plans that are subject to uncertainty.  The
use of the words "expects," "plans, " "anticipates" and other similar
words in conjunction with discussions of future operations or financial
performance identifies these statements.
     Forward-looking statements are based on current expectations of
future events.  The Company cannot ensure that any forward-looking
statement will be accurate, although the Company believes that it has
been reasonable in its expectations and assumptions.  Investors should
realize that if underlying assumptions prove inaccurate or that unknown
risks or uncertainties materialize, actual results could vary materially
from our projections.   The Company assumes no obligation to update any
forward-looking statements as a result of future events or developments.
In this filing, the Company discusses in more detail various factors that
could cause actual results to differ from expectations.  The Company
notes these factors as permitted by the Private Securities Litigation
Reform Act of 1995.  Investors are cautioned not to place undue reliance
on such statements that speak only as of the date made.  Investors also
should understand that it is not possible to predict or identify all such
factors and should not consider this list to be a complete statement of
all potential risks and uncertainties.

Consolidated Balance Sheet                             Johnson & Johnson
and Subsidiaries

At January 3, 1999 and December 28, 1997 (Dollars in Millions) (Note 1)
1998       1997
Assets
Current assets
Cash and cash equivalents (Notes 1 and 16)                   $   1,994
2,839
Marketable securities (Note 1)                                       789
255
Accounts receivable trade, less allowances $388 (1997, $358)
3,752            3,355
Inventories (Notes 1 and 2)                                  2,898
2,544
Deferred taxes on income (Note 6)                            1,183
833
Prepaid expenses and other receivables                               870
993

Total current assets                          $  11,486
10,819

Marketable securities, non-current (Note 16)                         437
397
Property, plant and equipment, net (Notes 1, 3, and 15)
6,395            5,887
Intangible assets, net (Notes 1, 5 and 15)                        7,364
3,266
Deferred taxes on income (Note 6)                               411
581
Other assets                                        1,199
1,158

Total assets                                  $  27,292
22,108

Liabilities and Shareowners' Equity
Current liabilities
Loans and notes payable (Note 4)                       $   2,753
720
Accounts payable                                            1,877
1,769
Accrued liabilities                                         3,012
2,318
Accrued salaries, wages and commissions                             445
342
Taxes on income                                       206            226

Total current liabilities
8,293                   5,375

Long-term debt (Note 4)                                      1,729
1,181
Deferred tax liability (Note 6)                                     578
175
Employee related obligations (Note 11)
1,738            1,562
Other Liabilities                                              877
949

Shareowners' equity
Preferred stock-without par value                                   -
- -
   (authorized and unissued 2,000,000 shares)
Common stock-par value $1.00 per share (Note 20)
1,535            1,535
   (authorized 2,160,000,000 shares; issued 1,534,824,000 shares)
Note receivable from employee stock ownership plan (Note 14)
(44)            (51)
Accumulated other comprehensive income (Note 8)
(322)              (370)
Retained earnings                                           13,968
12,747

                                                            15,137
13,861
Less: common stock held in treasury, at cost (Note 20)
1,060                995
   (145,560,000 and 144,864,000)
Total shareowners' equity                                  14,077
12,866

Total liabilities and shareowners' equity                   $  27,292
22,108

See Notes to Consolidated Financial Statements


Amounts have been restated under the pooling of interests method of
accounting to include the financial results of Centocor, Inc. acquired on
October 6,1999, see Note 1.
Consolidated Statement of Earnings           Johnson & Johnson and
Subsidiaries

(Dollars in Millions Except Per Share Figures) (Note 1)       1998
1997                                  1996

Sales to customers                    $23,995    22,830         21,755
Cost of products sold (1998 includes $60 of inventory write-offs
     for restructuring)                   7,604            7,230
7,079

Gross profit                             16,391          15,600
14,676

Selling, marketing and administrative expenses     9,027          8,756
8,427
Research expense                          2,336            2,209
1,962
Purchased in-process research and
     development (Notes 15 and 17)           298                -
- -
Interest income                             (277)            (213)
(149)
Interest expense, net of portion capitalized (Note 3)         129
124                                     133
Other expense, net                           143              137
283
Restructuring charge (Note 15)               553                -
- -

                                        12,209           11,013
10,656

Earnings before provision for taxes on income      4,182          4,587
4,020
Provision for taxes on income (Note 6)           1,179            1,276
1,138

Net earnings                           $ 3,003             3,311
2,882

Basic net earnings per share (Notes 1 and 19)   $   2.16            2.40
2.10

Diluted net earnings per share (Notes 1 and 19)         $   2.12
2.34                                    2.05

See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests method of
accounting to include the financial results of Centocor, Inc. acquired on
October 6,1999, see Note 1.

Consolidated Statement of Equity                       Johnson & Johnson
and Subsidiaries
                                            Note Receivable
Accumulated     Common
                                             From Employee
Other                       Stock       Treasury

Comprehensive                 Retained               Stock Ownership
Comprehensive       Issued          Stock
(Dollars in Millions) (Note 1)            Total             Income
Earnings                             Plan (ESOP)              Income
Amount                       Amount

Balance, December 31,1995       $ 9,261
9,707                                        (64)             198
1,535                    (2,115)
  Net earnings                              2,882        2,882
2,882
  Cash dividends paid                   (974)                    (974)
  Employee compensation
        and stock option plans                225                (218)
443
  Repurchase of common stock     (412)
(412)
  Issued upon stock offering            126                       70
56
  Issued upon conversion of debt    106                      53
53
  Amendment to Sales and
        Distribution Agreement (Lilly)        26                    13
13
  Business combinations                 318                     (490)
808
  Other comprehensive income,
          net of tax:
    Currency translation
            adjustment                             (272)          (272)
  Unrealized gains on securities       31              31
  Other comprehensive income                 (241)
(241)
  Total comprehensive income         2,641
  Note receivable from ESOP              7                              7
Balance, December 29, 1996      $11,324
11,043                           (57)                   (43)        1,535
(1,154)

  Net earnings                             3,311         3,311
3,311
  Cash dividends paid                (1,137)                 (1,137)
  Employee compensation
         and stock option plans               300                 (358)
658
  Repurchase of common stock     (628)
(628)
  Business combinations                   17                      (112)
129
  Other comprehensive income,
        net of tax:
   Currency translation
           adjustment                               (294)
(294)
  Unrealized gains (losses)
          on securities                               (33)
(33)
  Other comprehensive income         (327)
(327)
  Total comprehensive income                        2,984
  Note receivable from ESOP              6
6
Balance, December 28, 1997      $12,866                  12,747    (51)
(370)                      1,535       (995)

  Net earnings                              3,003     3,003
3,003
  Cash dividends paid                (1,305)                  (1,305)
  Employee compensation
        and stock option plans               378                  (484)
862
  Repurchase of common stock   (930)
(930)
  Business combinations                 10                       7
3
  Other comprehensive income,
         net of tax:
    Currency translation
           adjustment                               89          89
  Unrealized gains (losses)
         on securities                             (41)        (41)
  Other comprehensive income         48
48
  Total comprehensive income    3,051
  Note receivable from ESOP            7
7
Balance, January 3, 1999         $14,077                13,968
(44)                               (322)      1,535     (1,060)
Amounts have been restated under the pooling of interests method of
accounting to include the financial results of Centocor, Inc. acquired on
October 6,1999, see Note 1.
Consolidated Statement of Cash Flows         Johnson & Johnson and
Subsidiaries
 (Dollars in Millions) (Note 1)            1998    1997    1996

Cash flows from operating activities
Net earnings                                 $3,003        3,311
2,882
Adjustments to reconcile net earnings to cash flows:
   Depreciation and amortization of property and intangibles
1,285                                      1,082    1,023
   Increase in deferred taxes                    (272)       (118)
(10)
   Accounts receivable reserves                     24           61
53
   Purchased  in-process research and development         298
- -                                                 -
   Changes in assets and liabilities, net of effects from
      acquisition of businesses:
   Increase in accounts receivable              (163)         (380)
(375)
   Increase in inventories                      (100)         (180)
(246)
   Increase in accounts payable and accrued liabilities          646
487                                          257
   Decrease/(Increase) in other current and non-current assets
117                                              12            (46)
   Increase in other current and non-current liabilities        57
121                                          340

Net cash flows from operating activities   4,895    4,396   3,878

Cash flows from investing activities
Additions to property, plant and equipment    (1,545)      (1,415)
(1,378)
Proceeds from the disposal of assets          108               72
37
Acquisition of businesses, net of cash acquired (Note 17)    (3,818)
(180)                                       (233)
Other, principally marketable securities        (810)         (122)
(127)

Net cash used by investing activities      (6,065)         (1,645)
(1,701)

Cash flows from financing activities
Dividends to shareowners                      (1,305)       (1,137)
(974)
Repurchase of common stock                    (930)            (628)
(412)
Proceeds from short-term debt                2,424              300
282
Retirement of short-term debt                  (226)           (182)
(128)
Proceeds from long-term debt                    535                 7
126
Retirement of long-term debt                   (471)           (504)
(496)
Proceeds from issuance of common stock              -               -
126
Proceeds from the exercise of stock options             274
234                                           170

Net cash provided by (used by) financing activities              301
(1,910)                                    (1,306)

Effect of exchange rate changes on cash and cash equivalents
24                                                (69)          (21)
(Decrease) increase in cash and cash equivalents       (845)
772                                            850
Cash and cash equivalents, beginning of year (Note 1)         2,839
2,067                                       1,217

Cash and cash equivalents, end of year (Note 1)       1,994
2,839                                       2,067

Consolidated Statement of Cash Flows (con't)      Johnson & Johnson and
Subsidiaries
 (Dollars in Millions) (Note 1)            1998    1997    1996

Supplemental cash flow data
Cash paid during the year for:
   Interest, net of portion capitalized         102              95
126
   Income taxes                              1,310          1,431
1,210

Supplemental schedule of noncash investing
      and financing activities
Treasury stock issued for employee compensation
     and stock option plans, net of cash proceeds       621
451                                            285

Acquisitions of businesses
Fair value of assets acquired                 4,659            184
237
Fair value of liabilities assumed (including
      $296 of assumed debt)                  (545)            (4)
(4)

Net purchase price                         4,114     180      233

See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests method of
accounting to include the financial results of Centocor, Inc. acquired on
October 6,1999, see Note 1.
1
  Summary of Significant Accounting Principles

Basis of Presentation
The  supplemental consolidated financial statements of Johnson &  Johnson
have been prepared to give retroactive effect to the merger with Centocor
on  October  6, 1999.  Under the terms of the merger agreement,  Centocor
shareholders  received  approximately 45  million  shares  of  Johnson  &
Johnson common stock.  On a diluted basis when adjusted for stock options
outstanding and convertible debt, the total number of Johnson  &  Johnson
shares  to  be  issued total approximately 53 million shares.   Generally
accepted  accounting principles require giving effect  to  a  consummated
business combination accounted for under the pooling-of-interests  method
in financial statements that do not include the date of the consummation.
These  financial  statements  do  not extend  through  the  date  of  the
consummation;  however,  they  will become  the  historical  consolidated
financial  statements of Johnson & Johnson after the financial statements
covering the date of consummation of the business combination are issued.

The   supplemental  consolidated  financial  statements  (the  "financial
statements")  reflect  the  combination of  the  historical  consolidated
financial  statements  of Johnson & Johnson for the  fiscal  years  ended
January  3,  1999,  December 28, 1997, and December  29,  1996  with  the
historical  consolidated financial statements of Centocor for the  fiscal
years ended December 31, 1998, 1997, and 1996 respectively.

Principles of Consolidation
The  financial statements include the accounts of Johnson &  Johnson  and
subsidiaries.  Intercompany accounts and transactions are eliminated.

Cash Equivalents
The Company considers securities with maturities of three months or less,
when purchased, to be cash equivalents.

Investments
Short-term  marketable securities are carried at cost, which approximates
market value.  Long-term debt securities that the Company has the ability
and  intent  to hold until maturity are carried at amortized  cost.   The
equity  investments  classified as available  for  sale  are  carried  at
estimated  fair  value  with unrealized gains and losses  recorded  as  a
component  of  shareowners' equity.  The Company also classifies  certain
investments  as trading securities which are carried at fair  value  with
the   unrealized  gains  and  losses  reported  in  earnings.  Management
determines the appropriate classification of its investments in debt  and
equity   securities  at  the  time  of  purchase  and  reevaluates   such
determination at each balance sheet date.

Property, Plant, and Equipment and Depreciation
Property, plant, and equipment are stated at cost.  The Company utilizes
the straight-line method of depreciation over the estimated useful lives
of the assets:

Building and building equipment         20-40 years
Land and land improvements              10-20 years
Machinery and equipment            2.5-13 years


Revenue Recognition
The  Company  recognizes revenue from product sales when  the  goods  are
shipped and title passes to the customer.

Inventories
Inventories are stated at the lower of cost or market determined  by  the
first-in, first-out method.

Intangible Assets
The  excess  of the cost over the fair value of net assets  of  purchased
businesses  is  recorded as goodwill and is amortized on a  straight-line
basis  over  periods  of 40 years or less.  The cost  of  other  acquired
intangibles  is  amortized on a straight-line basis over their  estimated
useful  lives.  The Company continually evaluates the carrying  value  of
goodwill   and  other  intangible  assets.   Any  impairments  would   be
recognized  when  the expected future operating cash flows  derived  from
such intangible assets is less than their carrying value.

Financial Instruments
Gains and losses on foreign currency hedges of existing assets or
liabilities, or hedges of firm commitments, are deferred and recognized
in income as part of the related transaction.
   Unrealized gains and losses on currency swaps which hedge third  party
debt  are classified in the balance sheet as other assets or liabilities.
Interest  expense  under  these  agreements,  and  the  respective   debt
instrument  that  they hedge, are recorded at the net effective  interest
rate of the hedge transaction.
   In  the  event  of early termination of a currency swap contract  that
hedges  third  party  debt, the gain or loss  on  the  swap  contract  is
amortized  over  the remaining life of the related transaction.   If  the
underlying  transaction  associated with  a  swap,  or  other  derivative
contract,  is  accounted  for as a hedge and  is  terminated  early,  the
related derivative contract is terminated simultaneously and any gains or
losses would be included in income immediately.

Advertising
Costs  associated  with advertising are expensed in  the  year  incurred.
Advertising expenses worldwide, which are comprised of television,  radio
and  print media, were $1.19 billion in 1998, $1.26 billion in  1997  and
1996 respectively.

Income Taxes
The Company intends to continue to reinvest its undistributed
international earnings to expand its international operations; therefore
no tax has been provided to cover the repatriation of such undistributed
earnings.  At January 3, 1999, and December 28,1997 the cumulative amount
of undistributed international earnings was approximately $7.0 billion
and $5.9 billion, respectively.

Net Earnings Per Share
Basic earnings per share is computed by dividing net income available  to
common  shareowners  by  the weighted average  number  of  common  shares
outstanding  for  the period.  Diluted earnings per  share  reflects  the
potential  dilution that could occur if securities or other contracts  to
issue common stock were exercised or converted into common stock.

Risk and Uncertainties
The  preparation of consolidated financial statements in conformity  with
generally  accepted  accounting principles requires  management  to  make
estimates  and  assumptions  that affect the  amounts  reported.   Actual
results are not expected to differ materially from those estimates.

Annual Closing Date
The Company follows the concept of fiscal year which ends on the Sunday
nearest to the end of the month of December.  Normally each fiscal year
consists of 52 weeks, but every five or six years, as in 1998, the fiscal
year consists of 53 weeks.

Reclassification
Certain prior year amounts have been reclassified to conform with current
year presentation.

2  Inventories

At the end of 1998 and 1997, inventories were comprised of:

(Dollars in Millions)                        1998 1997

Raw materials and supplies                    $   776     660
Goods in process                                   510         430
Finished goods                          1,612     1,454
                                     $ 2,898      2,544

3 Property, Plant and Equipment

At the end of 1998 and 1997, property, plant and equipment at cost and
accumulated depreciation were:
(Dollars in Millions)                            1998         1997

Land and land improvements              $        466           413
Buildings and building equipment                       2,991
2,958
Machinery and equipment                        5,686        5,287
Construction in progress                       1,126           943
                                    10,269          9,601
Less accumulated depreciation                  3,874        3,714
                               $     6,395          5,887

The Company capitalizes interest expense as part of the cost of
construction of facilities and equipment.  Interest expense capitalized
in 1998, 1997 and 1996 was $72, $40 and $55 million, respectively.
     Upon retirement or other disposal of fixed assets, the cost and
related amount of accumulated depreciation or amortization are eliminated
from the asset and reserve accounts, respectively.  The difference, if
any, between the net asset value and the proceeds is adjusted to income.
For additional discussion on property, plant and equipment, see Note 15.


4  Borrowings

The components of long-term debt are as follows:
                                      Eff.
Eff.
(Dollars in Millions)         1998    Rate %   1997          Rate %

4.75% Convertible Subordinated
Debentures due 2005 (5)      $         460      4.75%                -
- -
8.72% Debentures due 2024                 300      8.72
300                      8.72%  Debentures due 2023
250                      6.73              250                 6.73
 7 3/8% Notes due 2002                  199          7.49
199                       7.49
8.25% Euro Notes due 2004                 199          8.37
199                                8.37
6.75% Convertible Subordinated
    Debentures due 2001                       -                      -
                    55        6.75
11 1/4% Italian Lire Notes
     due 1998 (1)                   -                   -
115                        4.88
5% Deutsche Mark Notes
     due 2001 (3)                   107     1.98             101
1.98
5.12% Notes due 2003 (4)                    60           0.82
- -                                 -
4 1/2% Currency Indexed Notes
     due 1998 (1)                         -          -
72                         5.26
8.18% to 8.25% Medium
     Term Notes due 1998                        -                 -
65                         8.23
Industrial Revenue Bonds                    50             5.28
57                         5.77
Other, principally international                     139
- -                                36              -
                                 1,764       6.25 (2)      1,449
6.96                 (2)
Less current portion                  35                        268
                         $      1,729                     1,181

The Company has access to substantial sources of funds at numerous banks
worldwide.  Total unused credit available to the Company approximates
$3.2 billion,  including $1.2 billion of credit commitments with various
worldwide banks, $800 million of which expire on October 1, 1999 and $400
million on October 6, 2003. Interest charged on borrowings under the
credit line agreements is based on either bids provided by the banks, the
prime rate or London Interbank Offered Rates (LIBOR), plus applicable
margins.  Commitment fees under the agreement are not material.
     The Company's shelf registration filed with the Securities and
Exchange Commission enables the Company to issue up to $2.59 billion of
unsecured debt securities, and warrants to purchase debt securities,
under its medium term note (MTN) program.  No MTN's were issued during
1998. At January 3, 1999 the Company had $2.29 billion remaining on its
shelf registration.
     In 1998 the Company issued $60 million of 5.12% notes due 2003, the
proceeds of which were used for general corporate purposes.  Long-term
debt includes convertible subordinated debentures issued by Centocor in
1991 and 1998.  Debentures issued by Centocor in 1991 were fully retired
in April, 1998.  Under the terms of the 4.75% Indenture issued in
February 1998 due February 2005 and following the merger with Johnson &
Johnson, bondholders are entitled to convert their debentures into
approximately 5,967,000 shares of Johnson & Johnson stock at a price of
$77.091per share.  After February 21, 2001 the debentures will be
redeemable at the option of the Company.
     Short-term borrowings and current portion of long-term debt amounted
to $2.7 billion at the end of 1998.  These borrowings are composed of
$2.2 billion U.S. commercial paper, at an average rate of 5.0% and $0.5
billion of local borrowings, principally by international subsidiaries.
     Aggregate maturities of long-term obligations for each of the next
five years commencing in 1999 are:
                                                       After
(Dollars in million) 1999   2000   2001  2002     2003 2003

                     $35        31   137  214     80        1267
 (1) The principal amounts of these debts issues include the effect of
foreign currency movements.  Such debt was converted to fixed or floating
rate U.S. dollar liabilities via interest rate and currency swaps.
Unrealized currency gains (losses) on currency swaps are not included in
the basis of the related debt transactions and are classified in the
balance sheet as other assets (liabilities).
(2) Weighted average effective rate.
(3) Represents 5% Deutsche Mark notes due 2001 issued by a Japanese
subsidiary and converted to a 1.98% fixed rate yen note via an interest
rate and currency swap.
(4) Represents 5.12% U.S. Dollar notes due 2003 issued by a Japanese
subsidiary and converted to a 0.82% fixed rate yen note via an interest
rate and currency swap.
(5) Represents 4.75% convertible subordinated debt issued by Centocor
prior to the merger with Johnson & Johnson.  The debentures are
convertible by the holders into approximately 5,967,000 shares of Johnson
& Johnson stock at a conversion price of $77.091 per share.  After
February 21, 2001 the debentures will be redeemable at the option of the
Company.  These bonds are due February 2005.


5  Intangible Assets

At the end of 1998 and 1997, the gross and net amounts of intangible
assets were:
(Dollars in Millions)                       1998   1997

Goodwill - gross                             $4,151       2,198
Less accumulated amortization                     331        241
Goodwill - Net                        $3,820          1,957
Patents and trademarks - gross                        1,760         1,079
Less accumulated amortization                     351        262
Patents & trademarks - Net                   $1,409          817
Other Intangibles  - gross                   $2,296          613
Less accumulated amortization                     161        121
Other Intangibles - Net                      $2,135          492

Total Intangible assets - gross                     $8,207     3,890
Less accumulated amortization                     843        624
Total intangible assets - net                $7,364       3,266


The weighted average amortization periods for goodwill, patents and
trademarks and other intangibles are 32 years, 21 years and 18 years,
respectively. For additional discussion on intangible assets, see Note
15.


6  Income Taxes

The provision for taxes on income consists of:

(Dollars in Millions)                            1998  1997 1996
Currently payable:
 U.S. taxes                                $ 991    953       674
 International taxes                        485    455        487

                                           1,476       1,408
1,161
Deferred:
 U.S. taxes                                 (180) (126)           8
 International taxes                      (117)      (6)       (31)
                                          (297)  (132)    (23)
                                         $1,179       1,276         1,138

Deferred income taxes are recognized for tax consequences of "temporary
differences" by applying enacted statutory tax rates, applicable to
future years, to differences between the financial reporting and the tax
basis of existing assets and liabilities.

Temporary differences and carryforwards for 1998 are as follows:

                                   Deferred Tax
(Dollars in Millions)                            Asset Liability

Employee benefit obligations                           $ 546
- -
Depreciation                               -        (329)
Non-deductible intangibles                        -       (851)
International R&D capitalized for tax               150              -
Reserves & liabilities                              609              -
Income reported for tax purposes             231           -
Miscellaneous international                         168        (276)
Loss carryforwards                           250           -
Miscellaneous U.S.                           439           -

Total deferred income taxes                      $2,393     (1,456)

The difference between the net Deferred Tax on income per the balance
sheet and the net Deferred Tax above is reflected in Taxes on Income. A
comparison of income tax expense at the federal statutory rate of 35% in
1998, 1997 and 1996, to the Company's effective tax rate is as follows:

(Dollars in Millions)                            1998  1997      1996

U.S.                                     $2,522  2,853        2,232
International                              1,660  1,734        1,788
Earnings before taxes on income:                $4,182      4,587
4,020

Statutory taxes                                   1,464     1,605
1,407
Tax rates:
Statutory                                 35.0%  35.0% 35.0%
Puerto Rico and Ireland operations                  (5.5)    (5.7)
(6.3)
Research tax credits                       (0.3)  (0.3)      (0.3)
Domestic state and local                    1.0    1.0        1.6
International subsidiaries excluding Ireland      (3.3)      (2.7)
(2.0)
IPR&D                                1.3        -            -
All other                                   0.1    0.5         0.3

Effective tax rate                        28.2%  27.8% 28.3%

The increase in the 1998 worldwide effective tax rate was primarily due
to the Company's purchased IPR&D charge. During 1998,  the Company had
subsidiaries operating in Puerto Rico under a tax incentive grant
expiring December 31, 2007.  In addition, the Company has subsidiaries
manufacturing in Ireland under an incentive tax rate effective through
the year 2010.

7  International Currency Translation
For translation of its international currencies, the Company has
determined that the local currencies of its international subsidiaries
are the functional currencies except those in highly inflationary
economies, which are defined as those which have had compound cumulative
rates of inflation of 100% or more during the past three years.
 In consolidating international subsidiaries, balance sheet currency
effects are recorded as a separate component of shareholders' equity.
This equity account includes the results of translating all balance sheet
assets and liabilities at current exchange rates, except for those
located in highly inflationary economies, principally Latin America,
which are        reflected in operating results.
 An analysis of the changes during 1998 and 1997 for  cumulative currency
translation adjustments is included in Note 8.
    Net currency transaction and translation gains and losses included in
other expense were after-tax losses of $15 million in 1998, after-tax
losses of $27 million in 1997 and after-tax gains of  $2 million in 1996.

8  Accumulated Other Comprehensive Income
In June 1997, the Financial Accounting Standards Board issued Statement
of Financial Accounting Standards No. 130 "Reporting Comprehensive
Income" that the Company adopted in the first quarter of 1998.  SFAS 130
requires presentation of comprehensive income and its components in the
financial statements.


     Components of other comprehensive income/(loss) consist of the
following:

                                             Accumulated
                    Foreign   Unrealized          Other
                    Currency  Gains/(Losses) Comprehensive
(Dollars in millions)         Translation    on Securities
Income/(Loss)

December 31, 1995        $   155              43                 198
1996 change                  (272)       31                (241)
December 29, 1996            (117)       74                  (43)
1997 change                  (294)     (33)                (327)
December 28, 1997            (411)       41                (370)
1998 change                     89          (41)                   48
January 3, 1999          $  (322)                  -
(322)

     The change in unrealized gains/(losses) on marketable securities
during 1998 includes reclassification adjustments of $48 million of
losses realized from the write down of marketable securities and the
associated tax benefit was $15 million. The tax effect on the components
of other comprehensive income are benefits of $19 million and $21 million
in 1998 and 1997, respectively and expense of $16 million in 1996 related
to unrealized gains (losses) on Securities.
     The currency translation adjustments are not currently adjusted for
income taxes as they relate to indefinite investments in non-US
subsidiaries.


9  Rental Expense and Lease Commitments
Rentals of space, vehicles, manufacturing equipment and office and data
processing equipment under operating leases amounted to approximately
$243 million in 1998, $238 million in 1997 and $240 million in 1996.
 The approximate minimum rental payments required under operating leases
that have initial or remaining noncancellable lease terms in excess of
one year at January 3, 1999 are:
                                                       After
(Dollars in Millions)   1999    2000    2001   2002    2003    2003
Total

                   $82     66      47      39     33      87     354

Commitments under capital leases are not significant.

10  Common Stock, Stock Options Plans and Stock Compensation Agreements

At January 3, 1999 the Company had twelve stock-based compensation plans.
Under the 1995 Employee Stock Option Plan, the Company may grant options
to its employees for up to 56 million shares of common stock.  The shares
outstanding are for contracts under the Company's 1986, 1991 and 1995
Employee Stock Option Plans, the 1997 Non-Employee Director's Plan and
the Mitek, Cordis, Biosense, Gynecare and Centocor Stock Option plans.
 Stock options expire ten years from the date they are granted and vest
over service periods that range from one to six years.  Shares available
for future grants amounted to 15.0 million, 22.7 million and 32.9 million
in 1998, 1997 and 1996, respectively.
 A summary of the status of the Company's stock option plans as of
January 3, 1999, December 28, 1997and December 29,1996 and changes during
the years ending on those dates, is presented below:

                                 Options      Weighted Average
(Shares in Thousands)                     Outstanding* Exercise Price

Balance at December 31, 1995                    81,600
24.72
 Options granted                       10,599                       44.27
 Options exercised                               (8,185)
16.12
 Options cancelled/forfeited                     (2,409)
29.30

Balance at December 29, 1996                    81,605
27.99
 Options granted                       13,053                       60.40
 Options exercised                             (11,157)
16.76
 Options cancelled/forfeited                     (2,240)
36.44

Balance at December 28, 1997                    81,261
34.51
 Options granted                       10,852
78.20
 Options exercised                             (11,414)
18.65
 Options cancelled/forfeited                     (2,304)
44.92

Balance at January 3, 1999                      78,395
42.55

*  Adjusted to reflect the 1996 two-for-one split

     The Company applies the provision of Financial Accounting Standards
No. 123, "Accounting for Stock-Based Compensation," that calls for
companies to measure employee stock compensation expense based on the
fair value method of accounting.  However, as allowed by the Statement,
the Company elected continued use of Accounting Principle Board (APB)
Opinion No. 25, "Accounting for Stock Issued to Employees," with pro
forma disclosure of net income and earnings per share determined as if
the fair value method had been applied in measuring compensation cost.
Had the fair value method been applied, net income would have been
reduced by $77 million or $.05 per share in 1998 and $35 million or $.02
per share in 1997.  In 1996, net income would have been reduced by $21
million or $.01 earnings per share.  These calculations only take into
account the options issued since January 1, 1995.  The average fair value
of options granted was $19.62 in 1998, $17.50 in 1997 and $13.37 in 1996.
The fair value  was estimated using the Black-Scholes option pricing
model based on the weighted average assumptions of:

                 1998    1997    1996

 Risk-free rate  4.52%   5.89%   6.11%
 Volatility              22.0%   21.5%    18.2%
 Expected life   5 yrs   5.3 yrs 7yrs
 Dividend yield  1.30%   1.43%   1.48%

The following table summarizes stock options outstanding and exercisable
at January 3, 1999:
 (Shares in Thousands)           Outstanding
Exercisable

                                 Average                Average
Exercise                 Average Exercise              Exercise
Price Range              Options Life (a) Price                  Options
Price

 $8.00-$22.28      12,928              3.2     $     18.64
11,494    $18.23
 $22.32-$42.86     22,850              4.7            24.96
18,123      24.66
 $43.13-$59.88     21,635              7.3            46.87
7,508       45.27
 $60.13-$83.72     20,982              9.3            71.92
184         71.89

 $8.00-$83.72      78,395              6.4     $     42.55
37,309    $27.06

 (a)  Average contractual life remaining in years

11  Employee Related Obligations

At the end of 1998 and 1997,  employee related obligations were:

(Dollars in Millions)                          1998     1997

Post retirement benefits                  $767      753
Post employment benefits                   144      166
Unfunded pension liabilities                    677      517
Certificates of extra compensation              150        126
Employee related obligations                           $1,738   1,562


12  Segments of Business and Geographic Areas
Segments of Business (1)
                                              Sales to Customers (2)
(Dollars in Millions)                                     1998   1997
1996

Consumer - Domestic                              $   3,325  3,240
3,166
     International                            3,201       3,258  3,198
     Total                                            6,526      6,498
6,364

Pharmaceutical - Domestic                           4,993   4,015
3,442
     International                            3,907       3,882  3,881
     Total                                          8,900   7,897
7,323

Professional - Domestic                             4,530   4,640
4,378
     International                            4,039       3,795  3,690
     Total                                          8,569   8,435
8,068

Worldwide total                                         $23,995   22,830
21,755

                     Operating Profit (3)                 Identifiable
Assets

(Dollars in Millions)           1998  1997(5) 1996           1998
1997 1996

Consumer                     $      414          551        346
4,645        4,745     4,874
Pharmaceutical            2,933       2,572   2,426              7,523
6,324        5,922
Professional                 941      1,543   1,406
12,856       7,773     7,505
Segments total            4,288       4,666   4,178
25,024    18,842    18,301

Expenses not allocated
 to segments (4)          (106)   (79)     (158)

General corporate                                           2,268
3,266    2,050

Worldwide total                        $  4,182    4,587   4,020
27,292     22,108   20,351

                     Additions to Property,                 Depreciation
and
                     Plant & Equipment                    Amortization
(Dollars in Millions)                1998           1997    1996
1998 1997  1996
Consumer             $     268   267          294           273    265
257
Pharmaceutical                   600   484            450          352
282    279
Professional                     627   573            594          629
495    446
Segments total                1,495           1,324            1,338
1,254       1,042      982
General corporate             50         91             40           31
40       41
Worldwide total           $  1,545           1,415       1,378
1,285      1,082      1,023

Geographic Areas [2]
                     Sales to Customers (2)                 Long-Lived
Assets (3)
(Dollars in Millions)           1998  1997    1996               1998
1997 1996
United States                           $12,848   11,895  10,986
8,619      5,728     5,268
Europe                    6,354        5,995    6,187
4,135      2,390     2,480
Western Hemisphere
 excluding U.S.                            2,105    2,044     1,926
429    457              441
Asia-Pacific, Africa                   2,688  2,896         2,656
402    384              435
Segments total                          23,995    22,830   21,755
13,585      8,959    8,624
General corporate                                             262
250     230
Other non long-lived assets
13,445     12,899    11,497
Worldwide total                       $23,995    22,830    21,755
27,292     22,108     20,351

[1] See Management's Discussion and Analysis for a description of the
segments in which the Company does business.
[2] Export sales and intersegment sales are not significant. No single
customer or country represents 10% or more of total sales.
[3] Prior years restated to conform to 1998 presentation according to
SFAS No. 131.
[4] Amounts not allocated to segments incude interest income/expense,
minority intersts and general corporate income and expense.
[5] 1998 results excluding Restructuring and In-Process Research and
Development charges: Consumer $658, Pharmaceutical $3,132 and
Professional $1,409.  See Note 15 for details of Restructuring and IPR&D
charges by segment.


13  Retirement and Pension PlansThe Company sponsors various retirement
and pension plans, including defined benefit, defined contribution and
termination indemnity plans, which cover most employees worldwide.  The
Company also provides postretirement benefits, primarily health care to
all domestic retired employees and their dependents.
Most international employees are covered by government-sponsored programs
and the cost to the company is not significant.
     Retirement plan benefits are primarily based on the employee's
compensation during the last three to five years before retirement and
the number of years of service. The Company's objective in funding its
domestic plans is to accumulate funds sufficient to provide for all
accrued benefits. International subsidiaries have plans under which funds
are deposited with trustees, annuities are purchased under group
contracts, or reserves are provided.
     In certain countries other than the United States, the funding of
pension plans is not a common practice as funding provides no economic
benefit. Consequently, the Company has several
pension plans which are not funded.
     The Company does not fund retiree health care benefits in advance
and has the right to modify these plans in the future.
     Effective December 29, 1997, the Company adopted Statement of
Financial Accounting Standards (SFAS) No. 132, "Employers' Disclosures
about Pensions and Postretirement Benefits" which standardizes the
disclosure
requirements for pensions and other postretirement benefits. The
Statement addresses disclosure only. It does not address liability
measurement or expense recognition. There was no effect on financial
position or net income as a result of adopting SFAS No. 132.

Net periodic benefit costs for the Company's defined benefit retirement
plans and other benefit plans for 1998, 1997 and 1996  include the
following components:

                           Retirement Plans                   Other
Benefit Plans
(Dollars in Millions)         1998  1997  1996        1998  1997 1996

Service cost           $185     166         159                 20
17        16
Interest cost                254      239    230                50
46        46
Expected return on plan assets       (291)  (256)      (231)
(14)       (3)          (3)
Amortization of prior service cost      17          16          14
2            1            1
Amortization of net transition asset  (14)    (13)       (13)
- -             -            -
Recognized actuarial (gain) / loss     (24)        (19)            2
8           (6)          (1)
Curtailments and settlements              2           1            -
- -             -            -

Net periodic benefit cost           $129      134         161
66           55           59


The net periodic cost attributable to domestic retirement plans included
above was $40 million in 1998, $50 million in 1997, and $84 million in
1996.
    The following tables provide the weighted-average assumptions used to
develop net periodic benefit cost and the actuarial present value of
projected benefit obligations:

                             Retirement Plans                 Other
Benefit Plans
Domestic Benefit Plans        1998  1997  1996        1998  1997 1996

Weighted average discount rate      6.75% 7.25% 7.75%       6.75%
7.25% 7.75%
Expected long-term rate of
    return on plan assets             9.0    9.0        9.0
9.0      9.0         9.0
Rate of increase in
    compensation levels               5.0    5.0        5.5        5.0
5.0      5.5


                            Retirement Plans                  Other
Benefit Plans
International Benefit Plans         1998  1997  1996        1998 1997
1996

Weighted average discount rate      5.50% 6.25% 6.50%       6.00%
7.00% 7.25%
Expected long-term rate of
    return on plan assets           7.75  7.75  7.75             -
- -           -
Rate of increase in
    compensation levels             3.50  4.25  4.75         4.25
5.00   5.00


Health care cost trends are projected at annual rates grading from    10%
for employees under age 65 and 7% for employees over age 65 down to 5%
for both groups by the year 2008 and beyond. The effect of a 1% change in
these assumed cost trends on the accumulated postretirement benefit
obligation at the end of 1998 would be a $99 million increase or an $88
million decrease and the effect on the service and interest cost
components of the net periodic postretirement benefit cost for 1998 would
be a $12 million increase or a $10 million decrease.

The following tables set forth the change in benefit obligations and
change in plan assets at year-end 1998 and 1997 for the Company's defined
benefit retirement plans and other postretirement plans:

(Dollars in Millions)               Retirement Plans         Other
Benefit Plans
                              1998  1997        1998  1997

Change in Benefit Obligation:
Benefit obligation - beginning of year    $3,704      3,412
691     591
Service cost                       185       166                       20
17
Interest cost                      254       239                50
46
Plan participant contributions                    11       10
- -           -
Amendments                           13        27                  -
- -
Actuarial loss (gain)                    325       123                  -
66
Curtailments & settlements                       (7)         1
- -           -
Total benefits paid                    (203)      (175)
(33)     (28)
Effect of exchange rates                        33        (99)
(2)        (1)

Benefit obligation - end of year          $4,315       3,704
726      691


Change in Plan Assets:
Plan assets at fair value - beginning of year   $3,694       3,330
46         41
Actual return on plan assets                   606        547
14           8
Company contributions                      45         35
29         24
Plan participant contributions                    11        10
- -            -
Acquisitions                         (4)          -                 -
- -
Benefits paid from plan assets               (193)       (158)
(32)      (27)
Effect of exchange rates                        14         (70)
- -            -

Plan assets at fair value - end of year   $4,173        3,694
57         46


Amounts recognized in the Company's balance sheet consist of the
following:
                              Retirement Plans                 Other
Benefit Plans
(Dollars in Millions)               1998  1997         1998 1997

Plan assets less than projected
   benefit obligation               $(142)   (10)            (668)
(645)
Unrecognized actuarial gains                (511)     (543)
(117)  (107)
Unrecognized prior service cost              98        102
(11)       (8)
Unrecognized net transition asset          (37)  (51)            -
- -

Total recognized in the consolidated
   balance sheet              $(592)      (502)              (796)
(760)


                              Retirement Plans         Other Benefit
Plans
(Dollars in Millions)               1998  1997         1998 1997

Book reserves                  $(726)      (592)                 (796)
(760)
Prepaid benefits                        109         75
- -           -
Intangible assets                   25         15              -
- -
Total recognized in consolidated
   balance sheet              $(592)       (502)             (796)
(760)


Plans with accumulated benefit obligations in excess of plan assets
consist of the following:
                              Retirement Plans                 Other
Benefit Plans
(Dollars in Millions)               1998  1997         1998 1997

Accumulated benefit obligation            $(558)      (435)
(696) (691)
Projected benefit obligation              $(723)      (566)
- -           -
Plan assets at fair value                 $ 162        126
57       46


14 Savings Plan

The Company has voluntary 401(k) savings plans designed to enhance the
existing retirement programs covering eligible employees.  The Company
matches a percentage of each employee's contributions consistent with the
provisions of the plan for which he/she is eligible.
   In the U.S. salaried plan, one-third of the Company match is paid in
Company stock under an employee stock ownership plan (ESOP) except for
Centocor employees for which the match for 1998 was 100% of Company
stock. In 1990, to establish the ESOP, the Company loaned $100 million to
the ESOP Trust to purchase shares of the Company stock on the open
market.  In exchange, the Company received a note, the balance of which
is recorded as a reduction of shareowners' equity.
   Total Company contributions to the plans were $65 million in 1998, $59
million in 1997, and $51 million in 1996.


15 Restructuring and In-Process Research and Development Charges

In the fourth quarter of 1998, the Company approved a plan to reconfigure
its global network of manufacturing and operating facilities with the
objective of enhancing operating efficiencies.  It is expected that the
plan will be completed over the next eighteen months.  Among the
initiatives supporting this plan were the closure of inefficient
manufacturing facilities, exiting certain businesses which were not
providing an acceptable return and related employee separations.  The
closure of these facilities represented approximately 10% of the
Company's manufacturing capacity.
  The estimated cost of this plan is $613 million which has been
reflected in cost of sales ($60 million) and restructuring charge ($553
million).  The charge consisted of employee separation costs of $161
million, asset impairments of $322 million, impairments of intangibles of
$52 million, and other exit costs of $78 million.  Employee separations
will occur primarily in manufacturing and operations facilities affected
by the plan.  The decision to exit certain facilities and businesses
decreased cash flows triggering the asset impairment.  The amount of
impairment of such assets was calculated using discounted cash flows or
appraisals.

Special charges recorded during 1998 were as follows:

                     Beginning            1998          Remaining
(Dollars in Millions)                     Accrual              Cash
Outlays       Accrual

Restructuring charges:
Employee separations $     161                        3
158
Other exit costs:
Distributor terminations              17
17
Dismantle/disposal costs              15
15
Lease terminations                    21
21
Customer compensation                 11
11
Other costs                    14                                 14

Total other costs                     78                     -
78

                      $     239                       3
236


Assets:
Machinery & equipment       $     215
Inventory                            60
Buildings                            32
Leasehold improvements               15

Total asset impairments     $     322

Intangible assets:
Menlo Care           $       26
Innotech                             20
Other                           6

Total intangible assets     $       52



Total restructuring plan    $     613
In process R&D                     298

Total special charges       $     911

The Menlo Care intangible asset was related to the Aquavene biomaterial
technology that was no longer in use with all other intangible assets
related to products that were abandoned by the Company due to the low
margin and/or lack of strategic fit.
   The restructuring plan consisted of the reduction of manufacturing
facilities around the world by 36, from 159 to 123 plants.  None of the
assets affected by this plan were held for disposal. The headcount
reduction for the year ended January 3, 1999 was approximately 225
employees.
  In connection with the businesses acquired in 1998, the Company
recognized charges for in-process research and development (IPR&D) in the
amount of $298 million related primarily to the DePuy and RETAVASE
acquisitions.  The value of the IPR&D projects was calculated with the
assistance of third party appraisers and was based on the estimated
percentage completion of the various research and development projects
being pursued using cash flow projections discounted for the risk
inherent in such projects. For additional discussion on acquisitions, see
Note 17.
   The special charges impacted the business segments as follows: the
special pre-tax charge for the Consumer segment was $244 million.  This
charge reflects $85 million for severance costs associated with the
termination of approximately 2,550 employees; $133 million for the write-
down of impaired assets and $26 million for other exit costs.
Acquisitions within the Pharmaceutical business segment resulted  in a
$134 million write-off  of purchased IPR&D.  Additionally, the
Pharmaceutical business segment recorded $65 million of the special
charge representing  $18 million for severance costs associated with the
termination of approximately 250 employees and $47 million for the write-
down of impaired assets. Acquisitions within the Professional business
segment resulted in a $164 million write-off of purchased IPR&D.
Additionally, the Professional business segment recorded other special
charges of $304 million.  This charge included $58 million for severance
costs associated with the termination of approximately 2,300 employees;
$194 million for the write-down of impaired assets and $52 million for
other exit costs.

16  Financial Instruments

Derivative Financial Instrument Risk

The Company uses derivative financial instruments to manage the impact of
interest rate and foreign exchange rate changes on earnings and cash
flows.  The Company does not enter into financial instruments for trading
or speculative purposes.
     The Company has a policy of only entering into contracts with
parties that have at least an "A" (or equivalent) credit rating.  The
counterparties to these contracts are major financial institutions and
the Company does not have significant exposure to any one counterparty.
Management believes the risk of loss is remote and in any event would be
immaterial.

Interest Rate and Foreign Exchange Risk Management

The Company uses interest rate and currency swaps to manage interest rate
and currency risk primarily related to borrowings.  Interest rate and
currency swap agreements that hedge third party debt mature with these
borrowings and are described in Note 4.
     The Company enters into forward foreign exchange contracts maturing
within five years to protect the value of existing foreign currency
assets and liabilities and to hedge future foreign currency product
costs.  The Company has forward exchange contracts outstanding at year-
end in various currencies, principally in U.S. Dollars, Belgian Francs
and Swiss Francs.  In addition, the Company has currency swaps
outstanding, principally in U.S. Dollars, Belgian Francs and French
Francs.  Unrealized gains and losses, based on dealer quoted market
prices, are presented in the following table:

                                            1998
                                 Notional
(Dollars in Millions)            Amounts    Gains      Losses

Forwards                         $6,848      94        227
Currency swaps                     3,422     25          89

Fair Value of Financial Instruments
The carrying amount of cash and cash equivalents and current and non-
current marketable securities approximates fair value of these
instruments.  In addition the carrying amount of long-term investments,
long-term debt, interest rate and currency swaps (used to hedge third
party debt) approximates fair value of these instruments for 1998 and
1997.
     The fair value of current and non-current marketable securities,
long-term debt and interest rate and currency swap agreements was
estimated based on quotes obtained from brokers for those or similar
instruments.  The fair value of long-term investments was estimated based
on quoted market prices at year-end.


Concentration of Credit Risk
The Company invests its excess cash in both deposits with major banks
throughout the world and other high quality short-term liquid money
market instruments (commercial paper, government and government agency
notes and bills, etc.).  The Company has a policy of making investments
only with commercial institutions that have at least an "A" (or
equivalent) credit rating.  These investments generally mature within six
months and the Company has not incurred any related losses.
     The Company sells a broad range of products in the health care field
in most countries of the world.  Concentrations of credit risk with
respect to trade receivables are limited due to the large number of
customers comprising the Company's customer base.  Ongoing credit
evaluations of customers' financial condition are performed and,
generally, no collateral is required.  The Company maintains reserves for
potential credit losses and such losses, in the aggregate, have not
exceeded management's expectations.


17  Mergers & Acquisitions

On October 6, 1999, Johnson & Johnson and Centocor, Inc. completed the
merger between the two companies.  This transaction was accounted for as
a pooling of interests.  Centocor had approximately 71 million shares
outstanding (83 million shares on a fully diluted basis) which were
exchanged for approximately 45 million shares of Johnson & Johnson common
stock.  On a diluted basis when adjusted for stock options outstanding
and convertible debt, the total number of Johnson & Johnson shares issued
total approximately 53 million shares.  Holders of Centocor common stock
received 0.6390 of a share of Johnson & Johnson common stock for each
share of Centocor common stock, valued at $95.47 per share.
     Centocor is a leading biopharmaceutical company that creates,
acquires and markets cost-effective therapies that yield long term
benefits for patients and the health care community.  Its products,
developed primarily through monoclonal antibody technology, help
physicians deliver innovative treatments to improve human health and
restore patients' quality of life.
     As described in Note 1, these financial statements have been
restated to give effect to Johnson & Johnson's merger with Centocor.  The
only adjustment to Centocor's historical financial statements has been
the reflection of income tax expense as if the companies had been
combined for all periods presented.  For 1998, 1997 and 1996, the revenue
and net earnings/(losses) of Centocor combined with Johnson & Johnson are
$338, $201 and $135 million respectively, for revenue and ($56), $8 and
($5) million respectively, of (losses)/earnings.
     During 1998, certain businesses were acquired for $4.1 billion and
the purchase method of accounting was employed.  The most significant
1998 acquisition was DePuy, Inc., a leading orthopaedics company.
DePuy's product lines include reconstructive products (implants for hips,
knees and extremities), spinal implants, trauma repair and sports-related
injury products.  Additionally, the Company completed the acquisition of
the U.S. and Canadian product rights for RETAVASE, an acute-care
cardiovascular drug, from Roche Healthcare.  RETAVASE is a recombinant
biologic cardiology care product administered for the treatment of acute
myocardial infarction (heart attack) to improve blood flow to the heart.
It is among the class of fibrinolytic drugs known as "clot busters."
RETAVASE received marketing authorization from the FDA in October 1996
and was launched in January 1997.
     The excess of purchase price over the estimated fair value amounted
to $3.3 billion.  This amount has been allocated to identifiable
intangibles and goodwill.  Approximately $298 million has been identified
as the value of IPR&D associated with the acquisitions.  The majority of
the value is associated with DePuy and RETAVASE projects.  The DePuy
projects focus on spinal and hip implants, which were near regulatory
approval as of the acquisition date.  The RETAVASE project represents
planned development of a combination cardiovascular therapy employing the
fibrinolytic drug RETAVASE in combination with REOPRO.  The remaining
effort to complete these projects is not expected to be material.
     The value of the IPR&D projects was calculated with the assistance
of third party appraisers and was based on the estimated percentage
completion of the various research and development projects being pursued
using cash flow projections discounted for the risk inherent in such
projects.  The discount rates used ranged between 13% and 20%.
     Management is primarily responsible for estimating the fair value of
the IPR&D.
     The Company is in the process of finalizing a plan to reconfigure
and integrate DePuy's operations, which will be completed within one year
of acquisition.  This effort is expected to result in employee
termination, facility closures and other related costs, which will be
recorded as an adjustment to the opening balance sheet and is not
expected to be material.  Pro forma information is not provided since the
impact of the acquisition does not have a material effect on the
Company's results of operations, cash flows or financial position.
     During 1997, certain businesses were merged with Johnson & Johnson
at a value, net of cash, of $737 million.  The mergers have been
accounted for as a pooling of interests; prior period financial
statements have not been restated since the effect of these mergers would
not materially effect previously issued financial statements.  The 1997
mergers included Biopsys Medical, Inc., Biosense, Inc. and Gynecare, Inc.
Biopsys Medical Inc. is an innovator and marketer of the MAMMOTOME Breast
Biopsy System.  Biosense, Inc. is a leader in developing medical sensor
technology and is developing several applications that will facilitate a
variety of diagnostic and therapeutic interventional and cardiovascular
procedures. Gynecare, Inc. is the developer and marketer of innovative,
minimally invasive medical devices utilized in the treatment of uterine
disorders.
     Certain businesses were acquired for $180 million during 1997 and
the purchase method of accounting was employed.  The most significant
1997 acquisition was Innotech, Inc., a developer and marketer of eyeglass
lens products.
     The excess of purchase price over the estimated fair value of 1997
acquisitions amounted to $157 million.  This amount has been allocated to
identifiable intangibles and goodwill.  Pro forma information is not
provided for in 1997, as the impact of the acquisition does not have a
material effect on the Company's results of operations, cash flows or
financial position.
     Divestitures in 1998 and 1997 did not have a material effect on the
Company's results of operations, cash flows or financial position.

18   Pending Legal Proceedings

The Company is involved in numerous product liability cases in the United
States, many of which concern adverse reactions to drugs and medical
devices.  The damages claimed are substantial, and while the Company is
confident of the adequacy of the warnings, which accompany such products,
it is not feasible to predict the ultimate outcome of litigation.
However, the Company believes that if any liability results from such
cases, it will be substantially covered by reserves established under its
self-insurance program and by commercially available excess liability
insurance.
   The Company, along with numerous other pharmaceutical manufacturers
and distributors, is a defendant in a large number of individual and
class actions brought by retail pharmacies in state and federal courts
under the antitrust laws.  These cases assert price discrimination and
price-fixing violations resulting from an alleged industry-wide agreement
to deny retail pharmacists price discounts on sales of brand name
prescription drugs.  The Company believes the claims against the Company
in these actions are without merit and is defending them vigorously.
   The Company, together with another contact lens manufacturer, a trade
association and various individual defendants, is a defendant in several
consumer class actions and an action brought by multiple State Attorneys
General on behalf of consumers alleging violations of federal and state
antitrust laws.  These cases assert that enforcement of the Company's
long-standing policy of selling contact lenses only to licensed eye care
professionals is a result of an unlawful conspiracy to eliminate
alternative distribution channels from the disposable contact lens
market.  The Company believes that these actions are without merit and is
defending them vigorously.
      The  Company is involved in a number of patent, trademark and other
lawsuits   incidental  to  its  business.   Among  those  is   a   patent
infringement action in which U.S. Surgical Corporation seeks  substantial
damages and an injunction based on what it alleges are infringing  trocar
surgical  instrument  sales by the Company's Ethicon  Endo-Surgery  unit.
The   Company   disputes  infringement  as  well  as  the  validity   and
enforceability  of the asserted patents and is vigorously contesting  the
claims. This case was subsequently settled with no montary payment  being
assessed or received.
      The  Company's Ortho Biotech subsidiary is party to an  arbitration
proceeding  filed  against it by Amgen, Ortho's  licensor  of  U.S.  non-
dialysis  rights to EPO, in which Amgen seeks to terminate  Ortho's  U.S.
license rights based on alleged deliberate EPO sales by Ortho during  the
early 1990's into Amgen's reserved dialysis market.  The Company believes
no  basis  exists  for  terminating Ortho's U.S. license  rights  and  is
vigorously  contesting  Amgen's  claims. However,  Ortho's  U.S.  license
rights  to EPO are material to the Company; thus, an unfavorable  outcome
could  have  a  material  adverse effect on  the  Company's  consolidated
financial position, liquidity or results of operations.
      In December 1998, Ortho Biotech was found in a separate arbitration
not  to have rights in what Amgen describes as its second-generation  EPO
product, known as Novel Erythropoiesis Stimulating Protein, or NESP.  The
effect  of  the ruling is to allow Amgen's NESP product, if approved,  to
compete with Ortho's EPO product in the U.S. non-dialysis market  and  in
all markets overseas, except China and Japan, which are reserved to Kirin-
Amgen. Currently, Ortho is Amgen's exclusive licensee for EPO in U.S. non-
dialysis  markets  and  in all ex-U.S. markets except  China  and  Japan.
Because  NESP is still in clinical trials, it is not possible to  predict
the impact on Ortho's marketing of EPO.
     The Company believes that the above proceedings, except as noted
above, would not have a material adverse effect on its results of
operations, cash flows or financial position.

19 Earnings Per Share

The following is a reconciliation of basic net earnings per share to
diluted net earnings per share for the years ended January 3, 1999,
December 28, 1997 and December 29, 1996:

(Shares in Millions)                       1998 (1)     1997
1996

Basic earnings per share               $    2.16            2.40
2.10
Average shares outstanding - basic      1,389.8         1,380.6
1,375.1
Potential shares exercisable
  under stock option plans                  68.8            70.5
74.2
Less: shares repurchased under
  treasury stock method                    (41.4)          (35.7)
(46.6)
Adjusted average shares
  outstanding - diluted                 1,417.2        1,415.4
1,402.7
Diluted earnings per share              $   2.12            2.34
2.05

This calculation does not include approximately 6 million shares related
to convertible debt as it would be anti-dilutive.

(1) 1998 results excluding Restructuring and In-Process Research &
Development charges are:
Basic EPS at $2.66 and diluted EPS at $2.61 (unaudited)


20   Capital and Treasury Stock

Changes in treasury stock were:
                                        Treasury Stock
Amounts in millions except number of shares in Thousands         Shares
Amount

Balance at December 31,1995            202,059        $  2,115
Employee compensation and stock option plans     (9,700)          (443)
Stock offering                            (2,572)            (56)
Conversion of debt                        (2,448)          (53)
Amendment to agreement with Lily                    (589)          (13)
Repurchase of common stock                 8,745             412
Business combinations                   (37,359)            (808)
Balance at December 29, 1996           158,136         1,154
Employee compensation and stock option plans   (11,794)         (658)
Repurchase of common stock               10,520            628
Business combinations                  (11,998)             (129)
Balance at December 28, 1997           144,864               995
Employee compensation and stock option plans   (11,906)            (862)
Repurchase of common stock               12,602              930
Business combinations                             -               (3)
Balance at January 3, 1999             145,560        $  1,060

Shares of common stock authorized and issued were 1,534,824,000 shares at
the end of 1998, 1997, 1996 and 1995.
21  Selected Quarterly Financial Data (Unaudited)


Selected unaudited quarterly financial data for the years 1998 and 1997
are summarized below:

                              1998                              1997

(Dollars in Millions               First        Second    Third
Fourth         First       Second    Third     Fourth
Except Per Share Amounts)               Quarter(1)   Quarter   Quarter
Quarter(2)  Quarter  Quarter   Quarter  Quarter
Segment sales to customers
Consumer                    $1,639      1,571      1,587       1,731
1,683       1,612     1,585      1,618
Pharmaceutical                       2,149      2,253      2,185
2,313        1,989       1,988     1,969      1,951
Professional                  2,052      2,050      2,039       2,426
2,088        2,152     2,083     2,112
Total sales                   5,840      5,874      5,811       6,470
5,760        5,752     5,637     5,681

Gross Profit                  4,042      4,047      4,021       4,281
3,971         3,979    3,869     3,781
Earnings before provision
   for taxes on income              1,294       1,391      1,321
176        1,305         1,295    1,201       786

Net earnings           919      1,018          964          102
911            910       858        632
Basic net earnings per share   $0.66        0.73         0.69
0.07          0.66           0.66      0.62       0.45
Diluted net earnings per share $0.65      0.72         0.68         0.07
0.64   0.65      0.61       0.45

(1) 1998 Q1 results excluding In-Process Research & Development charges:
Earnings before taxes $1,428; Net earnings $1,006; basic EPS $.72 and
Diluted EPS $.71.
 (2) 1998 Q4 results excluding Restructuring and In-Process Research &
Development charges:
Earnings before taxes $953; Net earnings $712; basic EPS $.51 and Diluted
EPS $.50.




                    REPORT OF INDEPENDENT ACCOUNTANTS

To the Shareowners and Board of Directors of Johnson & Johnson:

In our opinion, the accompanying supplemental consolidated balance sheets
and   the  related  supplemental  consolidated  statements  of  earnings,
consolidated  statements of equity, and consolidated statements  of  cash
flows present fairly, in all material respects, the financial position of
Johnson  &  Johnson and its subsidiaries at January 3, 1999 and  December
28,  1997,  and the results of their operations and their cash flows  for
each  of  the  three  years  in the period  ended  January  3,  1999,  in
conformity   with   generally  accepted  accounting  principles.    These
financial  statements are the responsibility of the Company's management;
our responsibility is to express an opinion on these financial statements
based  on  our  audits.   We  conducted our  audits  of  these  financial
statements in accordance with generally accepted auditing standards which
require that we plan and perform the audit to obtain reasonable assurance
about whether the financial statements are free of material misstatement.
An  audit  includes examining, on a test basis, evidence  supporting  the
amounts  and  disclosures  in  the financial  statements,  assessing  the
accounting  principles used and significant estimates made by management,
and  evaluating the overall financial statement presentation.  We believe
that  our  audits  provide a reasonable basis for the  opinion  expressed
above.

As described in Note 1, on October 6, 1999, Johnson & Johnson merged with
Centocor,  Inc. in a transaction accounted for as a pooling of interests.
The  accompanying  supplemental consolidated  financial  statements  give
retroactive effect to the merger of Johnson & Johnson with Centocor, Inc.
Generally  accepted accounting principles proscribe giving  effect  to  a
consummated  business  combination  accounted  for  by  the  pooling   of
interests method in financial statements that do not include the date  of
consummation.  These financial statements do not extend through the  date
of  consummation;  however, they will become the historical  consolidated
financial  statements  of  Johnson & Johnson after  financial  statements
covering the date of consummation of the business combination are issued.

/s/ PricewaterhouseCoopers LLP

PricewaterhouseCoopers LLP
New York, New York
January 25, 1999,
except as to the pooling of interests with
Centocor, Inc. which is as of October 6, 1999




<TABLE> <S> <C>

<ARTICLE> 5

<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                          JAN-02-2000
<PERIOD-END>                               OCT-03-1999
<CASH>                                           2,673
<SECURITIES>                                     1,092
<RECEIVABLES>                                    4,618
<ALLOWANCES>                                       334
<INVENTORY>                                      3,161
<CURRENT-ASSETS>                                13,207
<PP&E>                                          11,078
<DEPRECIATION>                                   4,636
<TOTAL-ASSETS>                                  29,241
<CURRENT-LIABILITIES>                            7,129
<BONDS>                                          2,489
                                0
                                          0
<COMMON>                                         1,535
<OTHER-SE>                                      14,370
<TOTAL-LIABILITY-AND-EQUITY>                    29,241
<SALES>                                         20,594
<TOTAL-REVENUES>                                20,594
<CGS>                                            6,261
<TOTAL-COSTS>                                    6,261
<OTHER-EXPENSES>                                 1,788
<LOSS-PROVISION>                                    30
<INTEREST-EXPENSE>                                 153
<INCOME-PRETAX>                                  4,782
<INCOME-TAX>                                     1,369
<INCOME-CONTINUING>                              3,413
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     3,413
<EPS-BASIC>                                     2.46
<EPS-DILUTED>                                     2.41


</TABLE>

1



               JOHNSON & JOHNSON AND SUBSIDIARIES

                   CONSOLIDATED BALANCE SHEET

                (Unaudited; Dollars in Millions)

                             ASSETS

                                           October 3,     January
3,
                                              1999           1999
Current Assets:

 Cash and cash equivalents             $ 2,673         1,994

 Marketable securities                   1,092           789

 Accounts receivable, trade, less
  allowances $334 (1998 - $388)          4,284         3,752

 Inventories (Note 3)                    3,161         2,898

 Deferred taxes on income                1,065         1,183

 Prepaid expenses and other
  receivables                              932           870

      Total current assets              13,207        11,486

Marketable securities, non-current         423           437

Property, plant and equipment, at cost  11,078        10,269

  Less accumulated depreciation and
    amortization                         4,636         3,874

                                         6,442         6,395

Intangible assets, net (Note 4)          7,456         7,364

Deferred taxes on income                   582           411

Other assets                             1,131         1,199


      Total assets                    $ 29,241        27,292

         See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests  method
of  accounting to include the financial results of Centocor, Inc.
acquired on October 6,1999, see Note 1.


               JOHNSON & JOHNSON AND SUBSIDIARIES
                   CONSOLIDATED BALANCE SHEET
                (Unaudited; Dollars in Millions)

              LIABILITIES AND SHAREOWNERS' EQUITY
                                         October 3,       January
3,
                                            1999             1999
Current Liabilities:

    Loans and notes payable         $ 1,462          2,753
    Accounts payable                  1,601          1,877
    Accrued liabilities               2,798          3,012
Accrued salaries, wages and commissions 642            445
    Taxes on income                     626            206

        Total current liabilities     7,129          8,293

Long-term debt                        2,452          1,729

Deferred tax liability                  594            578

Employee related obligations          1,912          1,738

Other liabilities                     1,249            877

Shareowners' equity:
    Preferred stock - without par value
  (authorized and unissued 2,000,000
   shares)                                -              -

    Common stock - par value $1.00 per share
  (authorized 2,160,000,000 shares;
   issued 1,534,865,000 shares and
   1,534,824,000 shares)              1,535          1,535

    Note receivable from employee stock
      ownership plan                    (41)           (44)

    Accumulated other comprehensive
   income (Note 7)                     (478)          (322)

    Retained earnings                15,969         13,968

                                                           16,985
15,137
      Less common stock held in treasury,
    at cost (145,201,000 & 145,560,000
     shares)                          1,080          1,060

      Total shareowners' equity      15,905         14,077

      Total liabilities and shareowners'
    equity                          $29,241         27,292

         See Notes to Consolidated Financial Statements
Amounts have been restated under the pooling of interests  method
of  accounting to include the financial results of Centocor, Inc.
acquired on October 6,1999, see Note 1.

               JOHNSON & JOHNSON AND SUBSIDIARIES

               CONSOLIDATED STATEMENT OF EARNINGS

            (Unaudited; dollars & shares in millions

                   except per share figures)

                                          Fiscal Quarter Ended
                                  Oct  3,    Percent    Sept  27,
Percent
                                  1999    to Sales     1998    to
Sales


Sales to customers (Note 5) $6,884     100.0   5,811      100.0
Cost of products sold        2,068      30.0   1,790       30.8

Gross profit                 4,816      70.0   4,021       69.2

Selling, marketing and
  administrative expenses    2,617      38.0   2,187       37.6
Research expense               635       9.2     524        9.0
Interest income                (63)      (.9)    (70)      (1.2)
Interest expense, net of
  portion capitalized           46        .7      32         .6
Other (income)expense, net      50        .7      27         .5

                             3,285      47.7   2,700       46.5

Earnings before provision
  for taxes on income        1,531      22.2   1,321       22.7

Provision for taxes on
  income (Note 2)              420       6.1     357        6.1


NET EARNINGS                $1,111      16.1     964       16.6

NET EARNINGS PER SHARE (Note 6)
  Basic                     $  .80               .69
  Diluted                   $  .78               .68

CASH DIVIDENDS PER SHARE    $  .28               .25

AVG. SHARES OUTSTANDING
  Basic                    1,389.9           1,390.0
  Diluted                  1,419.0           1,419.0

         See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests  method
of  accounting to include the financial results of Centocor, Inc.
acquired on October 6,1999, see Note 1.


               JOHNSON & JOHNSON AND SUBSIDIARIES

               CONSOLIDATED STATEMENT OF EARNINGS

            (Unaudited; dollars & shares in millions

                   except per share figures)

                                        Fiscal Nine Months  Ended
______
                                  Oct  3,    Percent    Sept  27,
Percent
                                  1999    to Sales     1998    to
Sales

Sales to customers (Note 5)$20,594     100.0  17,525      100.0
Cost of products sold        6,261      30.4   5,415       30.9

Gross profit                14,333      69.6  12,110       69.1

Selling, marketing and
  administrative expenses    7,642      37.1   6,443       36.8
Research expense             1,788       8.7   1,586        9.0
Purchased   in-process   R&D                                  134
 .8
Interest income               (170)      (.8)   (203)      (1.2)
Interest expense, net of
  portion capitalized          153        .7      95         .5
Other (income)expense, net     138        .7      49         .3

                             9,551      46.4   8,104       46.2

Earnings before provision
  for taxes on income        4,782      23.2   4,006       22.9

Provision for taxes on
  income (Note 2)            1,369       6.6   1,105        6.3


NET EARNINGS               $ 3,413      16.6   2,901       16.6

NET EARNINGS PER SHARE (Note 6)
  Basic                     $ 2.46              2.09
  Diluted                   $ 2.41              2.05

CASH DIVIDENDS PER SHARE    $  .81               .72

AVG. SHARES OUTSTANDING
  Basic                    1,390.1           1,390.0
  Diluted                  1,418.6           1,416.4

         See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests  method
of  accounting to include the financial results of Centocor, Inc.
acquired on October 6,1999, see Note 1.


                JOHNSON & JOHNSON AND SUBSIDIARIES
              CONSOLIDATED STATEMENT OF CASH FLOWS
                (Unaudited; Dollars in Millions)
                                               Fiscal Nine Months
Ended
                                                      Oct      3,
Sept 27,
                                                             1999
1998
CASH FLOWS FROM OPERATING ACTIVITIES
  Net earnings                              $3,413       2,901
  Adjustments to reconcile net earnings to
     cash flows:
   Depreciation and amortization of
      property and intangibles               1,136         933
   Purchased in-process R&D                    -           134
      Accounts   receivable   reserves                       (46)
(4)
   Increase in accounts receivable           (607)       (392)
   Increase in inventories                   (351)        (370)
   Changes in other assets and liabilities     882         339
   NET CASH FLOWS FROM OPERATING ACTIVITIES  4,427       3,541

CASH FLOWS FROM INVESTING ACTIVITIES
   Additions to property, plant and equipment(1,101)      (908)
   Proceeds from the disposal of assets              18     20
   Acquisition of businesses, net of cash
     acquired                               (228)         (415)
   Other, principally marketable securities  (358)        (112)
   NET CASH USED BY INVESTING ACTIVITIES   (1,669)      (1,415)

CASH FLOWS FROM FINANCING ACTIVITIES
   Dividends to shareowners                (1,090)        (969)
   Repurchase of common stock                (547)        (653)
   Proceeds from short-term debt             7,253        174
   Retirement of short-term debt           (8,468)        (193)
   Proceeds from long-term debt                776         449
   Retirement of long-term debt              (145)        (197)
   Proceeds from the exercise of stock
     options                                   186         226
   NET CASH USED BY FINANCING
     ACTIVITIES                            (2,035)      (1,163)

EFFECT OF EXCHANGE RATE CHANGES ON CASH
  AND CASH EQUIVALENTS                        (44)          22
INCREASE IN CASH AND CASH EQUIVALENTS          679         985
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD 1,994     2,839
CASH AND CASH EQUIVALENTS, END OF PERIOD   $ 2,673       3,824

         See Notes to Consolidated Financial Statements

Amounts have been restated under the pooling of interests  method
of  accounting to include the financial results of Centocor, Inc.
acquired on October 6,1999, see Note 1.



NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
NOTE   1   -   The  accompanying  unaudited  condensed  financial

statements have been prepared to give retroactive effect  to  the

merger  with  Centocor.  The financial statements  of  Johnson  &

Johnson  for  the nine month periods ended October  3,  1999  and

September  27,  1998,  have  been  combined  with  the  financial

statements of Centocor for the nine month periods ended September

30, 1999 and 1998, respectively.

   The  preparation  of financial statements during  the  interim

periods  requires  management  to  make  numerous  estimates  and

assumptions   that  impact  the  reported  amounts   of   assets,

liabilities,  revenues and expenses.  Estimates  and  assumptions

are  reviewed  periodically  and  the  effect  of  revisions   is

reflected in the results of operations of the interim periods  in

which changes are determined to be necessary.

  The financial statement results for the interim periods are not

necessarily  indicative of financial results for the  full  year.

These unaudited consolidated financial statements should be  read

in conjunction with the audited consolidated financial statements

and notes thereto included in Exhibit 99.1 of this filing.

NOTE 2 - INCOME TAXES

The effective income tax rates for 1999 and 1998 are as follows:
                                    1999            1998
    First Quarter                   29.8%           29.0%
    First Half                      29.2            27.9
    Nine Months                     28.6            27.6

The  effective income tax rates for the first nine months of 1999

and  1998 are 28.6% and 27.6%, respectively, as compared  to  the

U.S.  federal  statutory rate of 35%.  The  difference  from  the

statutory  rate is primarily the result of domestic  subsidiaries

operating in Puerto Rico under a grant for tax relief expiring on

December 31, 2007 and the result of subsidiaries manufacturing in

Ireland  under  an incentive tax rate expiring  on  December  21,

2010.


NOTE 3 - INVENTORIES

(Dollars  in  Millions)                 Oct. 3, 1999     Jan.  3,
1999

Raw materials and supplies         $   870           776
Goods in process                       544           510
Finished goods                       1,747         1,612
                                   $ 3,161         2,898






NOTE 4 - INTANGIBLE ASSETS

(Dollars  in Millions)                 Oct. 3, 1999   January  3,
1999

Intangible assets                  $ 8,542         8,207
Less accumulated amortization        1,086           843
                                   $ 7,456         7,364


The  excess  of  the cost over the fair value of  net  assets  of

purchased businesses is recorded as goodwill and is amortized  on

a straight-line basis over periods of up to 40 years.

The  cost  of  other  acquired  intangibles  is  amortized  on  a

straight-line basis over their estimated useful lives.


NOTE 5 - SEGMENTS OF BUSINESS AND GEOGRAPHIC AREAS

(Dollars in Millions)

SALES BY SEGMENT OF BUSINESS

                       Third Quarter               Nine Months
                               Percent                    Percent
                 1999    1998 Increase      1999   1998  Increase
Consumer
  Domestic    $   921     806   14.3       2,722  2,398   13.5
  International   783     781     .3       2,398  2,398     -
                1,704   1,587    7.4%      5,120  4,796    6.8%

Pharmaceutical
  Domestic      1,684   1,226   37.4       4,927  3,694   33.4
  International 1,051     959    9.6       3,215  2,893   11.1
                2,735   2,185   25.2%      8,142  6,587   23.6%

Professional
  Domestic      1,331   1,117   19.2       3,935  3,275   20.2
  International 1,114     922   20.8       3,397  2,867   18.5
                2,445   2,039   19.9%      7,332  6,142   19.4%

Domestic        3,936   3,149   25.0      11,584  9,367   23.7
International   2,948   2,662   10.7       9,010  8,158   10.4
  Worldwide    $6,884   5,811   18.5%     20,594 17,525   17.5%








NOTE 5 - SEGMENTS OF BUSINESS AND GEOGRAPHIC AREAS

(Dollars in Millions)

OPERATING PROFIT BY SEGMENT OF BUSINESS

                       Third Quarter               Nine Months
                               Percent                    Percent
                  1999  1998  Increase       1999  1998  Increase

Consumer           206   155     32.9         583    526   10.8
Pharmaceutical     976   850     14.8       3,063  2,455   24.8
Professional       385   338     13.9       1,268  1,078   17.6
  Segments total 1,567 1,343     16.7       4,914  4,059   21.1
Expenses not allocated
  to segments      (36)  (22)                (132)  (53)

  Worldwide total$1,5311,321     15.9       4,782  4,006   19.4


SALES BY GEOGRAPHIC AREA

                       Third Quarter               Nine Months
                              Percent                    Percent
                             Increase/                    Increase/
                  1999  1998(Decrease)       1999  1998  (Decrease)

U.S.            $3,935 3,149     25.0      11,584  9,367   23.7
Europe           1,577 1,496      5.4       5,028  4,644    8.3
Western Hemisphere
  excluding U.S.   514   520     (1.2)      1,503  1,564   (3.9)
Asia-Pacific,
  Africa           858   646     32.8       2,479  1,950   27.1

  Worldwide     $6,884 5,811     18.5%     20,594 17,525   17.5%

NOTE 6 - EARNINGS PER SHARE
   The  following is a reconciliation of basic net  earnings  per
share to diluted net earnings per share for the nine months ended
October 3, 1999 and September 27, 1998:
                                    Fiscal           Fiscal
                                  Quarter  Ended             Nine
Months Ended
                               Oct 3, Sept 27,   Oct 3,  Sept 27,
                                 1999              1998      1999
1998

Basic net earnings per share$    .80     .69      2.46     2.09
Average shares outstanding
  - basic                   1,389.9  1,390.0   1,390.1  1,390.0
Potential shares exercisable
  under stock option plans     68.0     69.2      68.3     68.0

Less: shares which could be
  repurchased under treasury
  stock method                (38.8)   (40.2)    (39.8)   (41.6)
Adjusted averages shares
  outstanding - diluted     1,419.0  1,419.0   1,418.6  1,416.4
Diluted earnings per share $    .78      .68      2.41     2.05



NOTE 7 - ACCUMULATED OTHER COMPREHENSIVE INCOME

   During  1998,  the  Company  adopted  Statement  of  Financial

Accounting  Standards  No. 130 "Reporting  Comprehensive  Income"

("SFAS  130").  SFAS 130 establishes standards for reporting  and

display  of  an  alternative income statement and its  components

(revenue,  expenses, gains and losses) in a full set  of  general

purpose financial statements.  The total comprehensive income for

the nine months ended October 3, 1999 is $3,275 million, compared

with  $2,880  million  for the same period  a  year  ago.   Total

comprehensive  income  includes  net  earnings,  net   unrealized

currency gains and losses on translation and net unrealized gains

and losses on available for sale securities.



NOTE 8 - ACQUISITIONS

During  the  first quarter, the Company completed the acquisition

of  the dermatological skin care business of S.C. Johnson &  Son,

Inc.   The  S.C. Johnson dermatological business is  composed  of

specialty brands marketed in the U.S., Canada and Western Europe.

The  primary brand involved in the transaction, AVEENO, is a line

of  skin care products including specialty soaps, bath, and anti-

itch treatments.

   Pro  forma  results  of  the acquisition,  assuming  that  the

transaction  was  consummated  at  the  beginning  of  each  year

presented,  would  not be materially different from  the  results

reported.



NOTE 9 - NEW ACCOUNTING PRONOUNCEMENT

   In  June 1998, the Financial Accounting Standards Board (FASB)
issued  Statement  of  Financial  Accounting  Standards  No.  133
"Accounting  for  Derivative Instruments and Hedging  Activities"
("SFAS  133").  This standard, as amended, is effective  for  all
fiscal quarters of fiscal years beginning after June 15, 2000.
NOTE 9 - NEW ACCOUNTING PRONOUNCEMENT (con't)
   SFAS  133 requires that all derivative instruments be recorded
on the balance sheet at their respective fair values.  Changes in
the fair value of derivatives are recorded each period in current
earnings  or  other  comprehensive  income,  depending   on   the
designation  of  the  hedge transaction.   For  fair-value  hedge
transactions in which the Company is hedging changes in the  fair
value  of an asset, liability or firm commitment, changes in  the
fair  value of the derivative instrument will generally be offset
by  changes in the fair value of the hedged item.  For cash  flow
hedge   transactions  in  which  the  Company  is   hedging   the
variability  of  cash  flows related to a  variable  rate  asset,
liability or forecasted transaction, changes in the fair value of
the derivative instrument will be reported in other comprehensive
income.   The gains and losses on the derivative instrument  that
are reported in other comprehensive income will be recognized  in
earnings  in  the periods in which earnings are impacted  by  the
variability of the cash flows of the hedged item.
   The  Company will adopt SFAS 133 in the first quarter of  2001
and does not expect it to have a material effect on the Company's
results of operations, cash flows or financial position.

NOTE 10 - RESTRUCTURING AND SPECIAL CHARGES

   In the fourth quarter of 1998, the Company approved a plan  to
reconfigure  its  global network of manufacturing  and  operating
facilities   with   the   objective   of   enhancing    operating
efficiencies.   It  is expected that the plan will  be  completed
over  the  next twelve months.  Among the initiatives  supporting
this   plan   were  the  closures  of  inefficient  manufacturing
facilities,  exiting certain businesses which were not  providing
an acceptable return and related employee separations.
   The  estimated cost of this plan is $613 million.  The  charge

consisted  of  employee separation costs of $161  million,  asset

impairments  of $322 million, impairments of intangibles  of  $52

million,

NOTE 10 - RESTRUCTURING AND SPECIAL CHARGES (con't)
and  other exit costs of $78 million.  Employee separations  will

occur   primarily  in  manufacturing  and  operations  facilities

affected  by  the plan.  The decision to exit certain  facilities

and  businesses  decreased expected future cash flows  triggering

the  asset  impairment.  The amount of impairment of such  assets

was calculated using discounted cash flows or appraisals.

   The components of the asset impairments and the impairments of

intangibles are as follows:

                          Value @
                      January 3, 1999
Assets:

Machinery & equipment     $215
Inventory                  60*
Buildings                   32
Leasehold improvements      15
Total asset impairments   $322

*Included in cost of products sold at year-end 1998


                          Value @
                      January 3, 1999
Intangible assets:

Menlo Care                $ 26
Innotech                    20
Other                        6
Total intangible assets   $ 52


  The Menlo Care intangible asset was related to the Aquavene

biomaterial technology that was no longer in use with all other

intangible assets related to products that were abandoned by the

Company due to the low margin and/or lack of strategic fit.

  The restructuring plan consisted of the reduction of

manufacturing facilities around the world by 36, from 159 to 123

plants.  None of the assets affected by this plan were held for

disposal.


NOTE 10 - RESTRUCTURING AND SPECIAL CHARGES (con't)
Severance and other exit costs were accrued at year-end 1998  and
payments  made through nine months ended October 3, 1999  are  as
follows:

                                 Beginning    Cash     Remaining
                                              Accrual     Outlays
Accrual

Employee Separations          $    158        25         133

Other exit costs:
Distributor terminations            17         6          11
Dismantle/disposal costs            15         4          11
Lease termination                   21        12           9
Customer compensation               11         5           6
Other                               14         7           7
Total other costs                   78        34          44

                              $    236        59         177

   Changes  in estimates to date have been immaterial.  The  $161
million  ($3  million  was paid at year-end  1998)  for  employee
separations  reflects  the  termination  of  approximately  5,100
employees  of  which 1,500 have been separated as of  October  3,
1999.



NOTE 11 - PENDING LEGAL PROCEEDINGS

   The  information called for by this footnote  is  incorporated
herein  by reference to Item 1 ("Legal Proceedings") included  in
Part II of this filing.



NOTE 12 - SUBSEQUENT EVENT

   On  November 8, 1999, Johnson & Johnson announced a definitive

merger agreement pursuant to which Johnson & Johnson will acquire

Innovasive  Devices, Inc.  The transaction will be accounted  for

under  the  purchase  method and is valued at  approximately  $85

million.    The  merger  is  subject  to  customary   conditions,

including approval by a

NOTE 12 - SUBSEQUENT EVENT (con't)

majority of the shareholders of Innovasive Devices and Hart-Scott

Rodino clearance.

   Innovasive Devices manufactures and sells devices  for  sports

medicine surgery, an area addressing soft tissue injuries in  the

knee, shoulder and other small joints.


Item 2 - MANAGEMENT'S DISCUSSION AND ANALYSIS OF
         FINANCIAL CONDITION AND RESULTS OF OPERATIONS

SALES AND EARNINGS
   Consolidated  sales  for the first nine months  of  1999  were

$20.59  billion, which exceeded sales of $17.53 billion  for  the

first  nine  months of 1998 by 17.5%.  The strength of  the  U.S.

dollar relative to the foreign currencies decreased sales for the

first  nine months of 1999 by 1.3%. Excluding the effect  of  the

stronger  U.S.  dollar  relative  to  foreign  currencies,  sales

increased 18.8% on an operational basis for the first nine months

of  1999.  Consolidated net earnings for the first nine months of

1999  were  $3.41  billion, compared with net earnings  of  $2.90

billion  for the first nine months of 1998.  Worldwide basic  net

earnings per share for the first nine months of 1999 were  $2.46,

compared  with  $2.09  for the same period  in  1998.   Worldwide

diluted net earnings per share for the first nine months of  1999

were  $2.41,  compared with $2.05 for the same  period  in  1998.

Consolidated  sales  for the third quarter  of  1999  were  $6.88

billion,  an increase of 18.5% over 1998 third quarter  sales  of

$5.81  billion.  The effect of the stronger U.S. dollar  relative

to  foreign  currencies decreased third quarter  sales  by  1.3%.

Consolidated  net  earnings for the third quarter  of  1999  were

$1.11  billion, compared with $.96 billion for the same period  a

year ago, an increase of 15.2%. Worldwide basic net earnings  per

share  for the third quarter of 1999 rose 15.9% to $.80, compared

with $.69 in the 1998 period.  Worldwide diluted net earnings per

share  for the third quarter of 1999 rose 14.7% to $.78, compared

with $.68 in 1998.



SALES AND EARNINGS (con't)

Domestic  sales  for the first nine months of  1999  were  $11.58

billion,  an increase of 23.7% over 1998 domestic sales of  $9.37

billion  for  the same period a year ago.  Sales by international

subsidiaries were $9.01 billion for the first nine months of 1999

compared  with $8.16 billion for the same period a year  ago,  an

increase of 10.4%.  Excluding the impact of the stronger value of

the dollar, international sales increased by 13.3%.

   Worldwide Consumer segment sales for the third quarter of 1999

were  $1.7 billion, an increase of 7.4% versus the same period  a

year ago.  Domestic sales were up 14.3% while international sales

gains in local currency of 7.0% were almost entirely offset by  a

negative  currency impact of 6.7%.  Consumer sales  were  led  by

continued strength in the skin care franchise, which includes the

NEUTROGENA, RoC and CLEAN & CLEAR product lines, as well as solid

results  from  McNeil  Consumer  Healthcare,  which  markets  the

TYLENOL  family  of products, BENECOL and other  over-the-counter

pharmaceuticals.

   During  the  quarter, the Company launched BENECOL  dressings,

margarine  spread  in tubs and snack bars in the  United  States.

BENECOL  contains the dietary ingredient stanol ester,  which  is

patented for use in reducing cholesterol.

  Worldwide pharmaceutical sales of $2.74 billion for the quarter

increased  25.2%  over the same period in 1998,  including  37.4%

growth  in  domestic sales and a 9.6% increase  in  international

sales.  International sales gains in local currency of 12.7% were

offset  by  a  negative currency impact of  3.1%.   Sales  growth

reflects the strong

SALES AND EARNINGS (con't)

performance  of  PROCRIT/EPREX,  for  the  treatment  of  anemia;

RISPERDAL,  an antipsychotic medication; DURAGESIC, a transdermal

patch  for chronic pain; LEVAQUIN, an anti-infective; ULTRAM,  an

analgesic, and the oral contraceptive line of products.

    During  the  quarter,  the  company  announced  a  definitive

agreement  for  a stock-for-stock merger with Centocor,  Inc.,  a

leader in monoclonal antibody technology and acute vascular  care

and immunology products.  The merger, valued at approximately  $5

billion, was completed on October 6, 1999.

   Also in the quarter Eisai, Inc. received approval from the FDA

for   ACIPHEX   (rabeprazole),  a  proton  pump   inhibitor   for

gastroesophageal   reflux  disease  (GERD),   GERD   maintenance,

duodenal  ulcers  and  treatment of  pathological  hypersecretory

conditions,   including  Zollinger-Ellison   syndrome.    Janssen

Pharmaceutica,  a wholly-owned subsidiary of Johnson  &  Johnson,

and  Eisai  have  entered  into a strategic  alliance  to  market

rabeprazole  worldwide with the exception of  Japan  and  certain

other territories.

   Additional  positive news in the quarter was the FDA  approval

for  new  indications of TOPAMAX (topiramate), an  anti-epileptic

drug.   Approval was received for adjunctive therapy for  partial

onset  seizures  in  pediatric patients and  primary  generalized

tonic-clonic seizures in adults and pediatric patients.

   Worldwide  sales of $2.45 billion in the Professional  segment

represented an increase of 19.9% over the third quarter of  1998.

Domestic  sales were up 19.2% while international sales  were  up

20.8%.  The 1998 acquisition of DePuy Inc., a leading orthopaedic

products manufacturer, contributed to the strong sales growth  in

the Professional

SALES AND EARNINGS (con't)

segment.   In addition, strong sales performance was achieved  by

Ethicon  Endo-Surgery's laparoscopy and wound  closure  products;

Ethicon's  Mitek  suture  anchors  and  Gynecare  women's  health

products, and Vistakon's disposable contact lens products.

  During the quarter, the Company received FDA approval to market

its  new CrossFlexTLC coronary stent, a laser-cut stainless steel

stent  designed  to  be  a  true workhorse  stent  that  combines

exceptional  deliverability with excellent scaffolding  and  high

radial   strength.   The  CrossFlexTLC  delivery  system,   which

incorporates  Cordis'  latest  balloon  catheter  technology,  is

specifically   engineered  to  minimize   the   risk   of   stent

embolization  through  the  use of Cordis'  proprietary  NestingT

technology.   This technology helps to secure the  stent  to  the

delivery balloon until the moment of deployment.

   Basic average shares of common stock outstanding in the  first

nine  months of 1999 were 1,390.1 million, compared with  1,390.0

million  for the same period a year ago.  Diluted average  shares

of common stock outstanding in the first nine months of 1999 were

1,418.6  million,  compared with 1,416.4  million  for  the  same

period a year ago.


LIQUIDITY AND CAPITAL RESOURCES

   Cash  and current marketable securities increased $982 million

during the first nine months of 1999 to $3,765 million at October

3,  1999.   Total  borrowings decreased $568 million  during  the

first nine months of 1999 to $3,914 million.  Net debt (debt  net

of  cash  and current securities) was $149 million at October  3,

1999 compared with $1,699 million at the end of 1998.  Total debt

represented 19.7% of total capital (shareowners' equity and total

borrowings)  at quarter end compared with 24.2%  at  the  end  of

1998.   For  the  period ended October 3,  1999,  there  were  no

material cash commitments.



LIQUIDITY AND CAPITAL RESOURCES (con't)

Additions  to  property, plant and equipment were $1,101  million

for the first nine months of 1999, compared with $908 million for

the same period in 1998.

   On October 18, 1999, the Board of Directors approved a regular

quarterly  dividend  rate  of  28 cents  per  share,  payable  on

December  7,  1999 to shareowners of record as  of  November  16,

1999.


YEAR 2000 COMPUTER SYSTEMS COMPLIANCE

   The  "Year 2000" issue relates to potential problems resulting

from a practice of computer programmers.  For some time, calendar

years  have  frequently been represented in computer programs  by

their last two digits.  Thus, "1998" would be rendered "98".  The

logic  of  the  programs frequently assumes that  the  first  two

digits  of  a year given in this format are "19".  It is  unclear

what would happen with respect to such computer programs upon the

change in calendar year from 1999 to 2000.  The program or device

might  interpret "00" as "2000", "1900", an error or  some  other

input.   In  such  a case, the computer program or  device  might

cease  to  function,  function improperly, provide  an  erroneous

result or act in some unpredictable manner.


  The Company has had a program in place since the fourth quarter

of  1996  to address Year 2000 issues in critical business  areas

related  to  its products, information management  systems,  non-

information  systems  with   embedded technology,  suppliers  and

customers.   A  report on the progress of this program  has  been

provided  to  the  Audit  Committee of  the  Company's  Board  of

Directors.  The Company has completed its review of its  critical

automated  information  systems and the  remediation  phase  with

respect to such critical systems is substantially complete.  Full

completion is expected during the fourth quarter of 1999.

    The  Company  is  also  in  the  process  of  reviewing   and

remediating,  where necessary, its other automated systems.   The

Company   has   substantially  completed   the   assessment   and

remediation of all such other

YEAR 2000 COMPUTER SYSTEMS COMPLIANCE (con't)

automated  systems  and full completion is  expected  during  the

fourth quarter of 1999.

  The Company has a plan for assessment and testing of all of its

products  and has made substantial progress toward completion  of

such  assessment and testing.  All current products are Year 2000

ready.   There  are  a  few remaining units  that  require  field

updates  at  customer  sites.  These updates  will  be  completed

during the fourth quarter of 1999.

   The  Company  has  engaged additional outside  consultants  to

examine   selected  critical  areas  in  certain  of   it   major

franchises.   In  addition, the Company has  contracted  with  an

independent  third  party  to conduct audits  of  critical  sites

worldwide to evaluate our programs, processes and progress and to

identify  any  remaining  areas of  effort  required  to  achieve

compliance.

  The total costs of addressing the Company's Year 2000 readiness

issues are not expected to be material to the Company's financial

condition  or  results of operations.  Since  initiation  of  its

program  in  1996,  the Company estimates that  it  has  expensed

approximately $195 million, on a worldwide basis, in internal and

external  costs  on  a  pre-tax basis to address  its  Year  2000

readiness issues.  These expenditures include information  system

replacement  and  embedded  technology  upgrade  costs  of   $111

million,  supplier and customer compliance costs of  $15  million

and  all  other  costs  of  $69 million.  The  Company  currently

estimates  that  the  total  of such  costs  for  addressing  its

internal  Year  2000  readiness,  on  a  worldwide  basis,   will

approximate

$200 million in the aggregate on a pre-tax basis.  These costs

are being expensed as they are incurred and are being funded

through operating cash flows.  No projects material to the

financial condition or results of operations of the Company have

been deferred or delayed as a result of this project.



YEAR 2000 COMPUTER SYSTEMS COMPLIANCE (con't)

The  ability of the Company to implement and effect its Year 2000

readiness  program  and the related costs or the  costs  of  non-

implementation,  cannot be accurately determined  at  this  time.

The  Company's automated systems (both information technology and

non-information   systems)   are  generally   complex   but   are

decentralized.

    Although a failure to complete remediation of one system  may

adversely  affect other systems, the Company does  not  currently

believe that such effects are likely.  If, however, a significant

number of such failures should occur, some of such systems  might

be  rendered inoperable and would require manual back-up  methods

or  other  alternatives, where available.  In such  a  case,  the

speed  of  processing  business transactions,  manufacturing  and

otherwise conducting business would likely decrease significantly

and the cost of such activities would increase, if they could  be

carried on at all.  That could have a material adverse effect  on

the   financial  condition  and  results  of  operations  of  the

business.

  The Company has highly integrated relationships with certain of

its   suppliers  and  customers.   These  include  among  others:

providers  of  energy, telecommunications, and raw materials  and

components,  financial institutions, managed  care  organizations

and large retail establishments.  The Company has been reviewing,

and  continues to review, with its critical suppliers  and  major

customers  the status of their Year 2000 readiness.  The  Company

has  in  place  a program of requesting assurances of  Year  2000

readiness  from such suppliers.  However, many critical suppliers

have  either declined to provide the requested assurances or have

limited the scope of assurances to which

YEAR 2000 COMPUTER SYSTEMS COMPLIANCE (con't)

they  are willing to commit.  The Company has completed its  plan

for monitoring of critical suppliers.

   The  Company  has contacted major customers  to  assess  their

readiness to deal with Year 2000 issues.  If a significant number

of  such  suppliers  and  customers were to  experience  business

disruptions  as  a result of their lack of Year  2000  readiness,

their  problems  could  have a material  adverse  effect  on  the

financial  position  and results of operations  of  the  Company.

This  analysis of potential exposures includes both the  domestic

and international operations of the Company.

   The  Company  believes that its most reasonably likely  "worst

case  scenario" would occur if a significant number  of  its  key

suppliers  or  customers were not fully Year 2000 functional,  in

which  case  the Company estimates that up to a 10  business  day

disruption  in  business operations could  occur.   In  order  to

address  this  situation, the Company has formulated  contingency

plans  intended  to deal with the impact on the Company  of  Year

2000  problems that may be experienced by such critical suppliers

and major customers.

   With  respect to critical suppliers, these plans may  include,

among  others,  arranging availability of substitute  sources  of

utilities,  closely managing appropriate levels of inventory  and

identifying  alternate sources of supply of  raw  materials.  The

Company is also alerting customers to their need to address these

problems,  but the Company has few alternatives available,  other

than reversion to manual methods, for avoiding or mitigating  the

effects of lack of Year 2000

YEAR 2000 COMPUTER SYSTEMS COMPLIANCE (con't)

readiness  by  major customers.  In any  event,  even  where  the

Company  has  contingency plans, there can be no  assurance  that

such plans will address all  the problems that may arise, or that

such plans, even if implemented, will be successful.

   Notwithstanding the foregoing, the Company has  no  reason  to

believe  that its exposure to the risks of supplier and  customer

Year 2000 readiness is any greater than the exposure to such risk

that  affects  its competitors generally.  Further,  the  Company

believes   that  its  programs  for  Year  2000  readiness   will

significantly improve its ability to deal with its own Year  2000

readiness  issues and those of suppliers and customers over  what

would have occurred in the absence of such a program.  That  does

not,  however, guarantee that some material adverse effects  will

not occur.

   The descriptions of Year 2000 issues set forth in this section

is  subject  to  the qualifications set forth  herein  under  the

heading "Cautionary Factors that May Affect Future Results".

CAUTIONARY FACTORS THAT MAY AFFECT FUTURE RESULTS

   This  Form  8-K  contains  "forward-looking  statements"  that

anticipate  results based on management's plans that are  subject

to   uncertainty.   Forward-looking  statements  do  not   relate

strictly to historical or current facts and may be identified  by

their   use   of   words   like   "plans,"   "expects,"   "will,"

"anticipates,"  "estimates," and other words of similar  meaning.

These  statements may address, among other things, the  Company's

strategy  for growth, product development, regulatory  approvals,

market  position, expenditures, financial results and the  effect

of Year 2000 readiness issues.

  Forward-looking statements are based on current expectations of

future  events.  The Company cannot guarantee that  any  forward-

looking statement will be accurate, although the Company believes

that  it has been reasonable in its expectations and assumptions.

Investors  should  realize that if underlying  assumptions  prove

inaccurate  or  that unknown risks or uncertainties  materialize,

actual results could differ materially from our projections.  The

Company  assumes  no  obligation to  update  any  forward-looking

statements  as  a result of new information or future  events  or

developments.

   In  this filing, the Company discusses in more detail  various

factors   that  could  cause  actual  results  to   differ   from

expectations.  That Exhibit from the Form 10-K is incorporated in

this  filing  by reference.  The Company notes these  factors  as

permitted  by  the Private Securities Litigation  Reform  Act  of

1995.  Investors are cautioned not to place undue reliance on any

forward-looking  statements.  Investors  also  should  understand

that  it  is not possible to predict or identify all such factors

and  should not consider this list to be a complete statement  of

all potential risks and uncertainties.

Item  3.  Quantitative and Qualitative Disclosures  About  Market

Risk

There has been no material change in the Company's assessment  of
its  sensitivity to market risk since its presentation set  forth
in  Item  7A,  "Quantitative  and Qualitative  Disclosures  About
Market  Risk," in its Annual Report on Form 10-K for  the  fiscal
year ended January 3, 1999.

Part II - OTHER INFORMATION
Item 1.    Legal Proceedings
The  Company is involved in numerous product liability  cases  in
the  United  States, many of which concern adverse  reactions  to
drugs  and medical devices.  The damages claimed are substantial,
and  while  the  Company  is confident of  the  adequacy  of  the
warnings  which  accompany such products, it is not  feasible  to
predict the ultimate outcome of litigation.  However, the Company
believes that if any liability results from such cases,  it  will
be  substantially covered by reserves established under its self-
insurance  program and by commercially available excess liability
insurance.
    The   Company,   along  with  numerous  other  pharmaceutical
manufacturers and distributors, is a defendant in large number of
individual  and  class  actions brought by retail  pharmacies  in
state  and federal courts under the antitrust laws.  These  cases
assert price discrimination and price-fixing violations resulting
from   an   alleged  industry-wide  agreement  to   deny   retail
pharmacists  price discounts on sales of brand name  prescription
drugs.   The  Company believes the claims against the Company  in
these actions are without merit and is defending them vigorously.
  The Company, together with another contact lens manufacturer, a
trade association and various individual defendants, is a
defendant in several consumer class actions and an action brought
by multiple State Attorneys General on behalf of consumers
alleging violations of federal and state antitrust laws.   These
cases assert that enforcement of the Company's long-standing
policy of selling contact lenses only to licensed eye care
professionals is a result of an unlawful conspiracy to eliminate
alternative distribution channels from the disposable contact
lens
Item 1.    Legal Proceedings (con't)
market.  The Company believes that these actions are without
merit and is defending them vigorously.
    The  Company's  Ortho  Biotech  subsidiary  is  party  to  an

arbitration  proceeding  filed  against  it  by  Amgen,   Ortho's

licensor of U.S. non-dialysis rights to EPO, in which Amgen seeks

to  terminate  Ortho's  U.S.  license  rights  based  on  alleged

deliberate  EPO  sales  by Ortho during  the  early  1990's  into

Amgen's reserved dialysis market.  The Company believes no  basis

exists  for  terminating  Ortho's  U.S.  license  rights  and  is

vigorously  contesting  Amgen's claims.   However,  Ortho's  U.S.

license  rights  to  EPO are material to the  Company;  thus,  an

unfavorable outcome could have a material adverse effect  on  the

Company's consolidated financial position, liquidity or   results

of operations.

   The  Company is also involved in a number of patent, trademark

and other lawsuits incidental to its business.

   The  Company  believes that the above proceedings,  except  as

noted  above,  would not have a material adverse  effect  on  its

results of operations, cash flows or financial position.



Item 5.    Other Information

On  July  19,  1999, Leo F. Mullin was elected to  the  Board  of

Directors  of Johnson & Johnson.  Mr. Mullin is president,  chief

executive officer and a director of Delta Air lLines.


Item 6.     Exhibits and Reports on Form 8-K

   (a)      Exhibit Numbers

            (1)     Exhibit 27 - Financial Data Schedule


   (b)      Reports on Form 8-K

             The  Company did not file any reports  on  Form  8-K
during
            the three month period ended October 3, 1999.






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<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          JAN-03-1999
<PERIOD-END>                               JAN-03-1999
<CASH>                                           1,994
<SECURITIES>                                       789
<RECEIVABLES>                                    4,140
<ALLOWANCES>                                       388
<INVENTORY>                                      2,898
<CURRENT-ASSETS>                                11,486
<PP&E>                                          10,269
<DEPRECIATION>                                   3,874
<TOTAL-ASSETS>                                  27,292
<CURRENT-LIABILITIES>                            8,293
<BONDS>                                          1,764
                                0
                                          0
<COMMON>                                         1,535
<OTHER-SE>                                      12,542
<TOTAL-LIABILITY-AND-EQUITY>                    27,292
<SALES>                                         23,995
<TOTAL-REVENUES>                                23,995
<CGS>                                            7,604
<TOTAL-COSTS>                                    7,604
<OTHER-EXPENSES>                                 2,336
<LOSS-PROVISION>                                    39
<INTEREST-EXPENSE>                                 129
<INCOME-PRETAX>                                  4,182
<INCOME-TAX>                                     1,179
<INCOME-CONTINUING>                              3,003
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     3,003
<EPS-BASIC>                                     2.16
<EPS-DILUTED>                                     2.12


</TABLE>

                                                       EXHIBIT 23


               CONSENT OF INDEPENDENT ACCOUNTANTS

We  hereby  consent  to the incorporation  by  reference  in  the
Registration  Statements of Johnson & Johnson on Form  S-8  (File
No.  33-52252, 33-40294, 33-40295, 33-32875, 33-7634,  033-59009,
333-38055,  333-40681, 333-26979 and 333-86611), Form  S-3  (File
No.  33-55977 and 33-47424) and Form S-4 (File No. 33-57583, 333-
00391,   333-38097,   333-30081  and   333-86611)   and   related
Prospectuses, of our report dated January 25, 1999, except as  to
the  pooling  of  interests with Centocor, Inc. which  is  as  of
October  6,  1999,  relating  to  the  supplemental  consolidated
financial statements of Johnson & Johnson and subsidiaries as  of
January 3, 1999 and December 28, 1997, and for each of the  three
years  in the period ended January 3, 1999, which report  appears
in this Current Report on Form 8-K.


/s/ PricewaterhouseCoopers LLP

PricewaterhouseCoopers LLP

New York, New York
December 13, 1999




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