RHONE POULENC RORER INC
10-Q, 1995-11-14
PHARMACEUTICAL PREPARATIONS
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               SECURITIES AND EXCHANGE COMMISSION
                     Washington, DC  20549

                           FORM 10-Q

 X   QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE
- ---- SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 1995

                               OR

     TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE
- ---- SECURITIES EXCHANGE ACT OF 1934

For the transition period from ______________ to_______________

Commission file number 1-5851

                    Rhone-Poulenc Rorer Inc.
- ----------------------------------------------------------------
     (Exact name of registrant as specified in its charter)

Commonwealth of Pennsylvania                     23-1699163
- ----------------------------------------------------------------
(State or other jurisdiction of              (I.R.S. Employer
incorporation or organization)              Identification Number)

500 Arcola Road
Collegeville, Pennsylvania                       19426-0107
- ----------------------------------------------------------------
(Address of principal                            (Zip Code)
 executive offices)

                          (610)454-8000
- ----------------------------------------------------------------
       (Registrant's telephone number, including area code)
                                
             (Former name, address and fiscal year,
                 if changed since last report.)

Indicate by check mark whether the registrant (1) has filed  all
reports  required to be filed by Section 13 or  15  (d)  of  the
Securities Exchange Act of 1934 during the preceding  12  months
(or for such shorter period that the registrant was required  to
file  such  reports), and (2) has been subject  to  such  filing
requirements for the past 90 days.   Yes   x    No
                                          ---        ---

Indicate  the  number  of  shares outstanding  of  each  of  the
issuer's  classes of common stock, as of the latest  practicable
date.

134,278,795 shares as of October 31, 1995.

The exhibit index is located on page 23.

<PAGE>
<PAGE>
                                
                    RHONE-POULENC RORER INC.
                                
                        TABLE OF CONTENTS
       --------------------------------------------------

                                                             Page
                                                             ----
                 PART I.  FINANCIAL INFORMATION


Item 1.  Financial statements:

 Report of Independent Accountants                               3
 
 Condensed Consolidated Statements of Income                     4
 
 Condensed Consolidated Balance Sheets                           5
 
 Condensed Consolidated Statements of Cash Flows                 6
 
 Notes to Condensed Consolidated Financial Statements         7-13
 
Item 2.  Management's Discussion and Analysis of Results of
          Operations and Financial Condition                 14-23





                   PART II.  OTHER INFORMATION


Item 1.  Legal Proceedings                                  24-28

Item 6.  Exhibits and Reports on Form 8-K                   29-30


                                  2

<PAGE>
<PAGE>

                REPORT OF INDEPENDENT ACCOUNTANTS



To the Shareholders of Rhone-Poulenc Rorer Inc.:

We have reviewed the accompanying condensed consolidated balance
sheet  of  Rhone-Poulenc  Rorer  Inc.  and  subsidiaries  as  of
September  30,  1995,  and  the related  condensed  consolidated
statements of income and cash flows for the three and nine month
periods  ended  September 30, 1995 and  1994.   These  financial
statements are the responsibility of the Company's management.

We conducted our review in accordance with standards established
by  the  American Institute of Certified Public Accountants.   A
review of interim financial information consists principally  of
applying  analytical  procedures to financial  data  and  making
inquiries  of  persons responsible for financial and  accounting
matters.   It  is substantially less in scope than an  audit  in
accordance  with  generally  accepted  auditing  standards,  the
objective of which is the expression of an opinion regarding the
financial statements taken as a whole.  Accordingly, we  do  not
express such an opinion.

Based   on  our  review,  we  are  not  aware  of  any  material
modifications that should be made to the condensed  consolidated
financial  statements  referred to  above  for  them  to  be  in
conformity with generally accepted accounting principles.

We   have  previously  audited,  in  accordance  with  generally
accepted  auditing standards, the consolidated balance sheet  of
Rhone-Poulenc  Rorer Inc. and subsidiaries as  of  December  31,
1994, and the related consolidated statements of income and cash
flows for the year then ended appearing in the  Company's   Form
8-K dated August  14,  1995.   Those financial  statements  were
prepared  to  give effect to the acquisitions from Rhone-Poulenc
S.A.  of  Cooperation Pharmaceutique Francaise and  a  Brazilian
pharmaceutical  business in the second  quarter  of  1995.   The
acquisitions of these entities under common control were treated
for  accounting  purposes in a manner similar to  a  pooling  of
interests as described in Note 2.  In our report, which includes
an  explanatory paragraph on the Company's change in its  method
of  accounting for income taxes in 1992, dated January 20,  1995
except  for the transactions described in Note 2 for which  date
is August 14, 1995, we expressed an unqualified opinion on those
consolidated   financial  statements.   In  our   opinion,   the
information set forth in the accompanying condensed consolidated
balance sheet as of December 31, 1994, is fairly stated, in  all
material respects, in relation to the consolidated balance sheet
from which it has been derived.


                                   /s/  COOPERS & LYBRAND L.L.P.
                                 --------------------------------
                                        COOPERS & LYBRAND L.L.P.


Philadelphia, Pennsylvania
October 20, 1995

                                 3
<PAGE>
<PAGE>

                PART I.    FINANCIAL INFORMATION


ITEM 1.     Financial Statements


            RHONE-POULENC RORER INC. AND SUBSIDIARIES
           CONDENSED CONSOLIDATED STATEMENTS OF INCOME
     (Unaudited - amounts in millions except per share data)


                                 Three Months Ended     Nine Months Ended
                                    September 30,         September 30,
                                 ------------------    -------------------
                                           Restated               Restated
                                   1995      1994         1995      1994
                                 --------  --------     --------  -------- 
 Net sales                       $1,212.7  $1,137.3     $3,552.4  $3,083.9
                                                                 
 Cost of products sold              419.9     396.4      1,251.6   1,070.2
                                                                 
 Selling, delivery and            
  administrative expenses           421.6     407.6      1,283.2   1,133.5
                                                                 
 Research and development          
  expenses                          189.7     153.3        532.7     430.1
                                                                 
 Restructuring and other charges      --        --           --      121.2
                                 --------  --------     --------  --------
    Operating income                181.5     180.0        484.9     328.9
                                                                 
 Interest expense - net              17.9      12.7         40.9      36.0
                                                                 
 (Gain) loss on sale of assets        --       (4.6)       (49.5)     (8.6)
                                                                 
 Other expense - net                  5.8       8.0         65.6      34.3
                                 --------  --------     --------  --------
    Income before income taxes      157.8     163.9        427.9     267.2
                                                                 
 Provision for income taxes          45.7      49.4        129.2      73.3
                                 --------  --------     --------  --------    
    Net income                      112.1     114.5        298.7     193.9
                                                                 
 Dividends on preferred stock        (4.8)     (4.9)       (16.2)    (13.8)
                                 --------  --------     --------  --------      
    Net income available to                                      
     common shareholders           $107.3    $109.6       $282.5    $180.1
                                 ========  ========     ========  ========
                                                                 
    Earnings per common share     $  0.80                         
                                 ========                                
    Earnings per common share,                                   
       pro forma                            $  0.80      $  2.09    $  1.28
                                           ========     ========   ========   
 Cash dividend per common share  $  0.30    $  0.28      $  0.90    $  0.84
                                                                 
 Average common shares 
   outstanding                     134.2      134.8        134.2      135.6

   See accompanying Notes to Condensed Consolidated Financial Statements.

                               4
<PAGE>
<PAGE>

            RHONE-POULENC RORER INC. AND SUBSIDIARIES
              CONDENSED CONSOLIDATED BALANCE SHEETS
                (Unaudited - dollars in millions)
                                
                                                                   Restated
                                                    September 30, December 31
                                                         1995        1994
                                                    ------------- -----------
ASSETS                                                             
Current:                                                           
   Cash and cash equivalents                             $  44.3   $  118.8
   Short-term investments                                   11.8        --
   Trade accounts and notes receivable, less                      
    reserves of $82.2 (1994: $78.6)                        777.9      812.1
   Inventories                                             713.3      612.5
   Other current assets                                    640.5      543.3
                                                    -------------- ----------
          Total current assets                           2,187.8    2,086.7
                                                                   
Time deposits, at cost                                      43.6       55.8
Property, plant and equipment, net of accumulated                 
   depreciation of $1,256.9 (1994: $1,111.1)             1,282.5    1,199.8
Goodwill, net of accumulated amortization of $240.7               
   (1994: $210.2)                                          747.7      705.9
Intangibles, net of accumulated amortization of $132.1               
   (1994: $121.2)                                          199.0      170.5
Other assets                                               632.8      433.6
                                                    -------------- ----------
          Total assets                                  $5,093.4   $4,652.3
                                                    ============== ==========   
LIABILITIES                                                        
Current:                                                           
   Short-term debt                                       $ 162.0   $  127.8
   Accounts payable                                        473.0      470.5
   Other current liabilities                               780.4      896.7
                                                    -------------- ----------
          Total current liabilities                      1,415.4    1,495.0
Long-term debt                                             872.2      439.9
Deferred income taxes                                       20.8       31.6
Other liabilities, including minority interests            948.6      575.4
                                                    -------------- ----------
          Total liabilities                              3,257.0    2,541.9
          
Contingencies                                                      
                                                                   
SHAREHOLDERS' EQUITY                                               
Market Auction Preferred Shares, without par value                    
   (liquidation preference $1,000 per share);
   authorized, issued and outstanding 
   1994-225,000 shares                                        --      225.0
Money market preferred stock, without par value                       
   (liquidation preference $100,000 per share);         
   authorized, issued and outstanding 1,750 shares          175.0     175.0
Common stock, without par value; stated value $1 per                  
   share; authorized 200,000,000 shares; issued
   and outstanding 134,278,795 shares
   (1994: 134,095,649 shares)                               139.3     139.1
Capital in excess of stated value                           144.9     412.2
Retained earnings                                         1,565.5   1,403.7
Employee Benefits Trust                                    (185.7)   (185.7)
Cumulative translation adjustments                           (2.6)    (58.9)
                                                       ----------- ----------
          Total shareholders' equity                      1,836.4   2,110.4
                                                       ----------- ----------
          Total liabilities and shareholders' equity     $5,093.4  $4,652.3
                                                       =========== ==========

   See accompanying Notes to Condensed Consolidated Financial Statements.

                                      5
<PAGE>
<PAGE>

            RHONE-POULENC RORER INC. AND SUBSIDIARIES
         CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                (Unaudited - dollars in millions)


                                                Nine Months Ended
                                                  September 30,
                                                ------------------
                                                          Restated
                                                 1995       1994
                                                -------   --------
CASH FLOWS FROM OPERATING ACTIVITIES:                       
  Net cash provided by operating activities     $ 275.6    $ 411.9
                                                            
CASH FLOWS FROM INVESTING ACTIVITIES:                       
Capital expenditures                             (192.7)    (144.4)
Businesses acquired                              (185.0)       --
Purchase of investments/product rights           (124.7)     (28.7)
Proceeds from sale of assets                       85.4       10.5
Net investment hedging, net                        (3.5)     (33.4)
                                                -------    -------           
   Net cash used in investing activities         (420.5)    (196.0)
                                                            
CASH FLOWS FROM FINANCING ACTIVITIES:                       
Debt borrowings (repayments):                               
   Long-term debt, net                             29.7        35.9
   Short-term debt, net                           394.3       (16.2)
Redemption of Market Auction Preferred Shares    (225.0)        --
Issuances of common stock                           6.9         1.8
Shares repurchased for Employee Benefits Trust      --       (109.5)
Dividends paid                                   (136.9)     (127.9)
                                                -------    --------      
   Net cash provided by (used in) financing 
      activities                                   69.0      (215.9)
                                                            
Effect of exchange rate changes on cash             1.4         3.9
                                                -------    --------            
Net increase (decrease) in cash and cash
   equivalents                                    (74.5)        3.9
Cash and cash equivalents at beginning of year    118.8        35.4
                                                -------    --------        
Cash and cash equivalents at September 30       $  44.3      $ 39.3
                                                =======    ========


See accompanying Notes to Condensed Consolidated Financial Statements.

                                       6
<PAGE>
<PAGE>
                                
                    RHONE-POULENC RORER INC.
      NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                           (Unaudited)
                                


NOTE 1.-  RESULTS FOR INTERIM PERIODS

In the opinion of management, the accompanying unaudited
condensed consolidated financial statements reflect all
adjustments, all of which are of a normal recurring nature,
necessary for a fair presentation of financial position, cash
flows and results of operations for the periods presented.

The statements are presented in accordance with the requirements
of Form 10-Q and do not include all disclosures required by
generally accepted accounting principles or those made in the
Annual Report on Form 10-K.  The Annual Report on Form 10-K for
the year 1994 and the Company's restated financial statements
for the year ended December 31, 1994 as filed on a Current
Report on Form 8-K dated August 14, 1995 are on file with the
Securities and Exchange Commission and should be read in
conjunction with these condensed consolidated financial
statements.

NOTE 2.-  ACQUISITIONS FROM RHONE-POULENC S.A.

In the 1995 second quarter, Rhone-Poulenc Rorer Inc. acquired
from Rhone-Poulenc S.A. ("RP") the businesses of Cooperation
Pharmaceutique Francaise ("Cooper"), primarily in France, and a
pharmaceutical business in Brazil for cash and preferred stock
of a French subsidiary aggregating approximately $270 million.
The preferred shares, accounted for as minority interest in
other liabilities, have a liquidation preference approximating
645 million French francs and pay dividends of 7.5% per annum on
a stated value of 145 million French francs.  The acquisition
agreements call for potential adjustments to the purchase price
of the businesses based on several factors, including earnings
performance.

The acquisitions of these entities under common control were
treated for accounting purposes on an "as-if pooling" basis and,
accordingly, the Company has restated its first quarter 1995 and
full year 1994 results to include the accounts of Cooper and the
Brazilian business as of April 1, 1994 and January 1, 1994,
respectively.  The effect of restatements in periods prior to
1994 was not material.  The assets and liabilities of the
acquired businesses were recorded by the Company at the carrying
values used by RP as of the restatement dates.  Earnings per
share for the restated periods reflect pro forma adjustments
giving effect to interest on indebtedness and preferred
dividends relative to the acquisition transactions.

NOTE 3.-  JOINT VENTURE

Under terms of a September 28, 1995 Amendment to the Joint
Venture Agreement (the "Amendment"), the Company's Armour
Pharmaceutical Company subsidiary ("Armour") and Behringwerke AG
("Behring"), a subsidiary of Germany's Hoechst AG, completed the
formation of their 50/50 global joint venture in the plasma
proteins business.

The joint venture's  Board of Directors will be formally
established on January 1, 1996, at which time joint control and
profit-sharing provisions also take effect.  Accordingly, the
Company will continue to consolidate the results of Armour
through the year 1995.

                                7
<PAGE>
<PAGE>

NOTE 4.-  RESTRUCTURING AND OTHER CHARGES

In June 1994, the Company recorded a $121.2 million pretax
charge in connection with a global restructuring plan that is
expected to be completed in 1995.  Annual pretax savings
associated with the plan approximated $20.0 million in 1994 and
should grow to over $50.0 million in 1996.  The restructuring
will reduce the Company's workforce by approximately 1,300
positions, or 6%; as of September 30, 1995, the Company's
workforce had been reduced by just under 1,000 employees.  To-
date, cash outlays related to the plan have totaled $69.9
million and are expected to exceed $90.0 million.  Cash outlays
for the three and nine month periods ended September 30, 1995
have approximated $8.7 million and $35.8 million, respectively.
Asset writeoffs in conjunction with certain production
facilities have totaled $22.7 million, including $3.3 million
during the nine months ended September 30, 1995.

A rollforward of the remaining 1994 restructuring provision from
December 31, 1994 is as follows:

                                                                    
                   December 31,   Payments/    Translation          
                       1994         asset      adjustments/  September 30,
                    (Restated)    writeoffs       other           1995
                    ---------     ---------    ---------      ------------
                                   (Dollars in millions)
Social costs        $   52.8      $  (31.3)    $    6.9         $  28.4
Third parties            8.4          (4.5)        (0.1)            3.8
Asset writeoffs          8.2          (3.3)        (3.3)            1.6
                    ---------     ---------    ---------      ------------
   Total            $   69.4      $  (39.1)    $    3.5        $   33.8
                    =========     =========    =========      ============

In 1993, the Company recorded charges of $93.8 million for the
cost of certain restructuring and manufacturing streamlining
programs, principally in Europe, and increased provisions for
certain litigation.  The programs include a plan to divest a
portion of a manufacturing facility in Monts, France by the end
of 1995.  Total workforce reductions associated with the plan
will approximate 800 positions; as of September 30, 1995, the
Company's workforce had been reduced by over 650 employees
relative to these activities.

A rollforward of the remaining 1993 restructuring provision from
December 31, 1994 is as follows:

                                                                    
                    December 31, Payments/    Translation          
                        1994       asset      adjustments/  September 30,
                     (Restated)  writeoffs        other           1995
                     ---------   ---------      ---------     ----------        
                                     (Dollars in millions)
Social costs         $   12.2    $   (6.3)      $    0.8      $    6.7
Asset writeoffs           9.0        (1.4)           0.7           8.3
                     ---------   ---------      ---------     ----------
   Total             $   21.2      $ (7.7)      $    1.5      $   15.0
                     =========   =========      =========     ==========

                                      8
<PAGE>
<PAGE>

NOTE 5.- GAIN ON SALE OF ASSETS AND OTHER EXPENSE - NET

Pretax gains from the sale of assets totaled $49.5 million ($.25
per share) for the nine months ended September 30, 1995 and
included gains on the sale of assets related to the Company's
Canadian over-the-counter business to Ciba-Geigy Limited and the
sale of certain European product rights during the 1995 first
quarter.

Other expense-net for the nine months ended September 30, 1995
included $13.0 million ($.06 per share) of acquired research and
development expense related to an additional investment in
Applied Immune Sciences, Inc. and pretax charges of $25.4
million ($.15 per share) related to the reassessment of the
carrying value of certain assets, including those associated
with the Company's prior investment in The Immune Response
Corporation, recorded in the first quarter.

NOTE 6.- INCOME TAXES

The Company records income tax expense based on an estimated
full year effective income tax rate.  The year-to-date reported
effective tax rate approximated 30.2% in 1995 compared with
27.4% in 1994.  The current year rate was affected by reduced
tax benefits from Puerto Rico operations and certain asset
sales/writeoffs.  The 1994 year-to-date effective tax rate was
favorably impacted by restructuring charges.

NOTE 7.-  INVENTORIES

Inventories consisted of the following:

                                                       December 31,
                                      September 30,        1994
                                          1995          (Restated)
                                     -------------     ------------
                                          (Dollars in millions)
Finished goods                       $     293.0       $     323.2
Work in process                            157.6             125.0
Raw materials and supplies                 262.7             164.3
                                     -------------     ------------
                                     $     713.3       $     612.5
                                     =============     ============

                                    9
<PAGE>
<PAGE>
<TABLE>
NOTE 8.-   SHAREHOLDERS' EQUITY
<CAPTION>
                              Market      Money                                                 
                              Auction    market    Common   Capital    Retained Employee  Cumulative
                             Preferred  preferred shares at in excess  earnings Benefits  translation
                              Shares      stock    stated   of stated            Trust    adjustments
                                                   value      value           
                             --------  ---------  --------  --------- --------  --------  -----------    
<S>                           <C>       <C>        <C>       <C>      <C>       <C>         <C>              
Balance, December 31, 1994  
   (Restated)                 $225.0    $175.0     $139.1    $412.2   $1,403.7  $  (185.7)  $(58.9)
Net income                                                               298.7 
Cash dividends, $.90 per                                  
   common share                                                         (120.7)
Dividends on preferred                 
   stock                                                                 (16.2)
Redemption of Market Auction                               
   Preferred Shares           (225.0)
Adjustment of capital                                          
   contributions for  
   acquisition liabilities                                   (273.2)
Issuance of shares under                                    
   employee benefit plans                             0.2       5.9        
Translation adjustments, net              
   of $5.2 million reductions    
   due to hedging activities                                                                  56.3         
                             -------    ------    -------   -------   --------    ---------  -------
Balance, September 30, 1995  $   --     $175.0    $ 139.3   $ 144.9   $1,565.5    $  (185.7) $(2.6)
                             =======    ======    =======   =======   ========    =========  =======
                       
In the 1995 third quarter, the Company redeemed Series A, C and D of Market
Auction Preferred Shares for $225 million plus accrued dividends.

As discussed in Note 2, the Company has restated its 1994 results to include 
the accounts of Cooper and the Brazilian business as of April 1, 1994 and 
January 1, 1994, respectively.  The assets and liabilities of the acquired
businesses were recorded by the Company at the carrying values used by RP as 
of the restatement dates and the value of net assets acquired was reflected 
in capital in excess of stated value as a capital contribution from RP. 
In 1995, the Company reduced capital in excess of stated value to reflect 
the purchase obligation related to the acquisition transactions of 
approximately $270 million.

</TABLE>
                                     10
<PAGE>
<PAGE>

NOTE 9.-  RELATED PARTY TRANSACTIONS

Receivables from Rhone-Poulenc S.A. and affiliates at September
30, 1995 included $8.2 million in accounts receivable from sales
of products to RP and $48.3 million classified as other current
assets.

Accounts payable related to the purchase of materials and
services from RP were $14.6 million at September 30, 1995;
accrued and other liabilities due to RP totaled $17.1 million.

As of September 30, 1995, the Company had $51.6 million short-
term and $60.1 million long-term debt outstanding with RP.

Sales to RP totaled $7.5 million in the third quarter and $24.0
million for the nine-month period; services purchased from and
interest paid to RP totaled $9.0 million in the third quarter
and $28.2 million for the first nine months of 1995.  For the
comparable 1994 periods on a restated basis, sales to RP were
$8.8 million and $22.8 million, respectively.  Services
purchased from and interest paid to RP totaled $9.0 million and
$27.0 million, respectively.

In the 1995 second quarter, the Company acquired Cooper and a
pharmaceutical business in Brazil from RP for cash and preferred
stock of an RPR subsidiary aggregating approximately $270
million.  The preferred shares, accounted for as minority
interest in other liabilities, have a liquidation preference
approximating 645 million French francs (approximately $130
million) and pay dividends of 7.5% per annum on a stated value
of 145 million French francs.  See Note 2.

NOTE 10.- CONTINGENCIES

The Company is involved in litigation incidental to its business,
including but not limited to: (1) approximately 373 pending lawsuits
in the United States, Canada and Ireland against the Company and its
Armour Pharmaceutical Company subsidiary ("Armour"), in which it is
claimed by individuals infected with the Human Immunodeficiency Virus
("HIV") that their infection with HIV and, in some cases, resulting
illnesses, including Acquired Immmune Deficiency Syndrome-related
conditions or death therefrom, may have been caused by admin- 
istration of antihemophilic factor ("AHF") concentrates processed
by Armour in the early and mid-1980s.  Armour has also
been named as a defendant in six proposed class action lawsuits
filed on behalf of HIV-infected hemophiliacs and their families.
None of the cases involves Armour's currently distributed AHF
concentrates; (2) legal actions pending against one or more
subsidiaries of the Company and various groupings of more than
one hundred pharmaceutical companies, in which it is generally
alleged that certain individuals were injured as a result of the
development of various reproductive tract abnormalities because
of in utero exposure to diethylstilbestrol ("DES") (typically,
   -- -----
two former operating subsidiaries of the Company are named as
defendants, along with numerous other DES manufacturers, when
the claimant is unable to identify the manufacturer); (3)
antitrust actions in the U.S. alleging that the Company engaged
in price discrimination practices to the detriment of certain
independent community pharmacists, retail chains and consumers;
(4) alleged breach of contract by a subsidiary of the Company
with respect to agreements involving another company's
bisphosphonate compound and the Company's licensed product
Lozol(r); and (5) potential responsibility relating to past
waste disposal practices, including potential involvement, for
which the Company believes its share of liability, if any, to be
negligible, at three sites on the U.S. National Priority List
created by Superfund legislation.

                                  11
<PAGE>
<PAGE>

The eventual outcomes of the above matters of pending litigation
cannot be predicted with certainty.  The defense of these
matters and the defense of expected additional lawsuits related
to these matters may require substantial legal defense
expenditures.  The Company follows Statement of Financial
Accounting Standards No. 5 in determining whether to recognize
losses and accrue liabilities relating to such matters.
Accordingly, the Company recognizes a loss if available
information indicates that a loss or range of losses is probable
and reasonably estimable.  The Company estimates such losses on
the basis of current facts and circumstances, prior experience
with similar matters, the number of claims and the anticipated
cost of administering, defending and, in some cases, settling
such claims.  The Company has also recorded as an asset certain
insurance recoveries which are determined to be probable of
occurrence on the basis of the status of current discussions
with its insurance carriers.  If a contingent loss is not
probable but is reasonably possible, the Company discloses this
contingency in the notes to its consolidated financial
statements if it is material.  Based on the information
available, the Company does not believe that reasonably possible
uninsured losses in excess of amounts recorded for the above
matters of litigation would have a material adverse impact on
the Company's financial position, results of operations or cash
flows.

NOTE 11.- FISONS

On October 20, 1995, the Company gained operational control of
the U.K.-based pharmaceutical company Fisons plc via beneficial
ownership of a majority of Fisons' total share capital. By mid-
November 1995, RPR had completed the purchase of 93% of the
outstanding shares of Fisons for approximately $2.7 billion.  Of
this amount, $1.75 billion was financed under the Societe
General and Banque Nationale de Paris loan facility
arrangements; $700 million, the majority of which represented
open market share purchases, was financed under short-term loan
arrangements with certain banks; a further $250 million
represented drawdowns of the Company's medium-term lines of
credit.  The weighted average annual effective interest rate on
the borrowings approximates 6.1%.  The $2.7 billion drawings
mature in December 1995 at which time the Company intends to
establish longer-term financing arrangements. The acquisition
will be accounted for using the purchase method.

NOTE 12.- APPLIED IMMUNE SCIENCES, INC.

In October 1995, the Company and Applied Immune Sciences, Inc.
("AIS"), a pioneer in cell and gene therapy, announced that they
entered into a definitive agreement and plan of merger.  The
agreement provides for the acquisition by RPR of the 7.2 million
AIS shares not previously owned by RPR at a cash price of $11.75
per share, or approximately $84.4 million. The acquisition is
expected to be financed under available medium-term lines of
credit bearing interest at an annual rate of LIBOR plus a
margin.

Prior to the transaction, the Company owned approximately 47% of
AIS and accounted for this interest under the equity method.
The acquisition of the remaining outstanding shares of AIS will
be accounted for under the purchase method and, accordingly, the
purchase price will be allocated to 53% of AIS' assets and
liabilities based on their estimated fair values as of the
acquisition date.

                              12
<PAGE>
<PAGE>

Consummation of the tender offer is subject to the valid tender
of a majority of the AIS shares not held by RPR and certain
other conditions.  Completion of the merger is subject to the
closing of the tender offer and the absence of any legal
prohibitions.  Subject to the foregoing, the transaction is
expected to be completed by the end of 1995.


                              13
<PAGE>
<PAGE>

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF RESULTS OF
           OPERATIONS AND FINANCIAL CONDITION


Rhone-Poulenc Rorer Inc. ("RPR" or "the Company") is one of  the
largest  research-based pharmaceutical companies in  the  world.
RPR  was  formed in 1990 by the combination of Rorer Group  Inc.
and  substantially all of the Human Pharmaceutical  Business  of
Rhone-Poulenc  S.A.  ("RP"), based in Paris,  France.   RP  owns
approximately two-thirds of RPR's common stock and controls  the
Company.

In  the 1995 second quarter, RPR acquired from RP the businesses
of   Cooperation   Pharmaceutique  Francaise  ("Cooper"),   with
operations primarily in France, and a pharmaceutical business in
Brazil.  The acquisitions of entities under common control  were
treated for accounting purposes on an "as-if pooling" basis and,
accordingly,  RPR  restated its first quarter 1995  results  and
full year 1994 results to include the accounts of Cooper and the
Brazilian  business  as of April 1, 1994 and  January  1,  1994,
respectively.   Earnings  per share  for  the  restated  periods
reflect  pro  forma  adjustments giving effect  to  interest  on
indebtedness and preferred dividends relative to the acquisition
transactions. The discussion that follows reflects the effect of
such restatements.

Results of Operations (Three and nine months ended September 30,
1995 versus comparable 1994 periods)

At  $107  million, third quarter net income available to  common
shareholders was essentially level with the prior year ($.80 per
common  share  in both years).  Net income for  the  first  nine
months of 1995 totaled $283 million ($2.09 per common share)  as
compared  with  $180 million ($1.28 per common share)  in  1994.
Results  for  the  1994  year-to-date  period  included   pretax
restructuring  charges of $121 million ($.58 per common  share).
Results  for the first nine months of 1995 included a  $.04  per
share  benefit from the net effects of asset sales  and  certain
one-time  charges recorded in the first quarter.  The comparable
prior  year-to-date period included $.04 per share of  gains  on
sales of assets.

Sales

Third  quarter 1995 sales ($1,213 million) increased  by  7%  on
both  an  as-reported  and operational basis  as  the  favorable
effects  of  currency fluctuations due to a weaker  U.S.  dollar
(+4%)  were  offset  by  product divestitures,  principally  the
Company's  U.S. and Canadian over-the-counter businesses  (-4%).
Operational  sales growth resulted from volume increases  (+5%),
including  new product presentations, and net higher  prices  in
Europe  and  in  the U.S. prescription pharmaceuticals  business
(+2%).   For  the  first  nine months of  1995,  reported  sales
increased  by  15%  including currency  fluctuations  (+7%)  and
product  divestitures  (-4%).  On an  operational  basis,  sales
growth was 12%, including 3% from the inclusion of Cooper  sales
for  nine  months in 1995 compared with six months in  1994,  2%
from new product presentations, and 2% from net price changes in
Europe  and in the U.S. (prescription pharmaceuticals and plasma
proteins).

                           14
<PAGE>
<PAGE>

In   the   tables   and  discussion  which  follow,   percentage
comparisons  of  sales are presented excluding  the  effects  of
currency fluctuations unless otherwise noted.

Sales  by geographic area (excluding product divestitures)  were
as follows:

                             Three Months ended      
                                September 30,
                             --------------------
                                         Restated          %
     ($ in millions)          1995         1994         Change
                             -------      -------        -----
     U.S.                    $   313      $   318           8%
                             -------      -------        -----
     France                      416          385          --%
     Other Europe                276          253           4%
     Rest of World               208          181          25%
                             -------      -------        -----
     Total Non-U.S.              900          819           6%
                             -------      -------        -----
     Total Sales             $ 1,213      $ 1,137           7%
                             =======      =======        =====

                              Nine Months ended     
                                September 30,
                             --------------------
                                         Restated          %
     ($ in millions)          1995         1994         Change
                             -------      -------        -----
     U.S.                    $   813      $   820          11%
                             -------      -------        -----
     France                    1,326        1,052          12%
     Other Europe                840          732           5%
     Rest of World               573          480          28%
                             -------      -------        -----
     Total Non-U.S.            2,739        2,264          13%
                             -------      -------        -----
     Total Sales             $ 3,552      $ 3,084          12%
                             =======      =======        =====
<PAGE>

Three-  and  nine-month sales in the United States  exceeded  prior
year   levels   as   the  Company's  prescription   pharmaceuticals
Azmacort(r),   Lovenox(r)   and  DDAVP(r)   and   plasma   proteins
(recombinant  Factor VIII offerings and Albuminar(r)) continued  to
perform well.  In France, increased quarterly sales of Doliprane(r)
and   Maalox(r)  and  contributions  from  the  recently   acquired
Biogalenique generics business were offset by reduced sales of anti-
infectives.   Sales  growth  in  France  on  a  year-to-date  basis
reflected  improved  performance of analgesics and  anti-infectives
and  also  benefited from the inclusion of nine  months  of  Cooper
sales  as  compared  to  six months in  1994.   In  Other  European
markets, sales of prescription pharmaceuticals continued to recover
over  the  prior  year periods in Germany (+14% on  a  year-to-date
basis)  and in Italy (+8%) where Granocyte(r) was launched  in  the
second  quarter.  Ethical product sales in the U.K. (-4%)  included
positive  performance by Granocyte(r) and Imovane(r)/Amoban(r)  but
continued to be negatively impacted by generic competition.   Sales
increases in Central and Eastern Europe added to Other Europe sales
growth for the three- and nine-month periods.  In the Rest of World
area,  sales  expansion  continued  in  South  American  countries,
particularly Argentina and Brazil, with sales gains posted by anti-
infectives  and  bone metabolism/rheumatology products.   Quarterly
and  year-to-date sales in Japan (Albuminar(r) and Maalox(r))  also
exceeded prior year levels.

                                15
<PAGE>
<PAGE>

Sales by therapeutic area were as follows:

                                  Three Months ended     
   Therapeutic Area/Principal       September 30,
            Offerings
                                 --------------------- 
                                              Restated     %
         ($ in millions)          1995          1994     Change*
   -------------------------------------      --------    -----

   Clexane(r)/Lovenox(r)           $ 70          $ 51      29%
   Dilacor(r) XR                     36            38      -3%
   Lozol(r)/Indapamide               20            26     -24%
   Selectol(r)/Selecor(r)            19            14      28%
   Total Cardiovascular             235           221       2%
                                                           
   Zagam(tm)                         --             6       --
   Granocyte(r)                      12             6       --
   Total Anti-infectives/  
     Oncology                       175           139      22%
                                                           
   Albuminar(r)                      48            39      21%
   Monoclate-P(r)/Factor VIII        47            38      21%
   Total Plasma Proteins            143           126      11%
                                                           
   Doliprane(r)                      32            26      13%
   Imovane(r)/Amoban(r)              33            24      30%
   Total CNS/Analgesics             149           122      17%
                                                           
   Azmacort(r)                       49            40      21%
   Nasacort(r)                       21            21      -3%
   Total Respiratory                120           115       2%
                                                           
   Maalox(r)                         42            59     -29%
   Total Gastrointestinal            94           109     -15%
                                                           
   Calcitonins                       26            20      29%
   Orudis(r)/Profenid(r)/Oruvail(r)  59            48      22%
   Total Bone Metabolism/                                  
      Rheumatology                  100            82      21%
                                                           
   DDAVP(r)                          27            22      22%
   Other Therapeutic Areas          197           223     -16%

*     Percentage  change  calculation  excludes  effects   of   currency
fluctuations.

<PAGE>

                                 Nine Months ended
    Therapeutic Area/Principal      September 30,
            Offerings            ------------------
                                           Restated     %
         ($ in millions)          1995       1994     Change*
   -------------------------------------   --------    -----
                                                            
   Clexane(r)/Lovenox(r)           $211        $149      30%
   Dilacor(r) XR                     81          76       6%
   Lozol(r)/Indapamide               47          56     -15%
   Selectol(r)/Selecor(r)            53          39      24%
   Total Cardiovascular             666         586       6%
                                                      
   Zagam(tm)                         17           6       --
   Granocyte(r)                      33          11       --
   Total Anti-infectives/  
      Oncology                      495         400      15%
                                                      
   Albuminar(r)                     146         114      24%
   Monoclate-P(r)/Factor VIII       153         111      32%
   Total Plasma Proteins            428         354      17%
                                                      
   Doliprane(r)                      98          71      23%
   Imovane(r)/Amoban(r)              92          65      29%
   Total CNS/Analgesics             420         342      13%
                                                      
   Azmacort(r)                      129          95      36%
   Nasacort(r)                       55          59      -6%
   Total Respiratory                319         289       7%
                                                            
   Maalox(r)                        123         163     -27%
   Total Gastrointestinal           281         319     -17%
                                                      
   Calcitonins                       77          61      19%
   Orudis(r)/Profenid(r)/Oruvail(r) 153         142       3%
   Total Bone Metabolism/                                   
      Rheumatology                  275         241       8%
                                                      
   DDAVP(r)                          62          54      16%
   Other Therapeutic Areas          669         553      12%

*     Percentage  change  calculation  excludes  effects   of   currency
fluctuations.

<PAGE>

Three-month sales of cardiovascular products increased modestly  as
continued  growth of Clexane(r)/Lovenox(r) in the U.S., France  and
Germany  was  partially  offset  by  reduced  quarterly  sales   of
Dilacor(r) XR and indapamide products in the U.S. Lower quarter-on-
quarter Dilacor(r) XR sales resulted from the introductory stocking
of certain new packagings in the prior year. Although Dilacor(r) XR
lost  U.S.  FDA  exclusivity  in  mid-1995,  management  does   not
anticipate   sales  erosion  in  the  current  year  from   generic
intrusion. In 1995, both Lovenox(r) and Dilacor(r) XR were approved
by the FDA for new indications.

Increased third quarter sales of anti-infectives resulted from  the
continued   sales  expansion  of  antibiotics  in  South   America,
particularly  with  respect  to  the  antiparasitic  Flagyl(r).   A
quarter-on-quarter  reduction  in anti-infective  sales  in  France
resulted from the absence of Zagam(tm) sales due to an incidence of
photosensitivity.  Future Zagam(tm) sales levels in France will  be
determined  by  the outcome of a review of product indications  and
labeling requirements by the European Union regulatory authority in
November 1995.

                                  16
<PAGE>
<PAGE>

The  largest  contributors  to quarterly  sales  of  the  Company's
oncological  product Granocyte(r)  were France, Italy and  Germany;
Granocyte(r)  is  now  available in all European  Union  countries.
Third quarter 1995 introductions of oncology products included  the
launch  in France of Campto(r), for treatment of colorectal cancer,
and  the  Canadian launch of Taxotere(r), for use in  treatment  of
advanced  breast and non-small cell lung cancer.  In October  1995,
Taxotere(r) received an approvable letter from the U.S. FDA for use
in  treatment of advanced breast cancer when other lines of therapy
fail.   Taxotere(r)  has  now  been  approved  or  recommended  for
approval  in  seven  countries  and  has  been  launched  in  three
countries.

Third quarter and year-to-date sales growth of plasma proteins  was
driven by double-digit sales increases of Albuminar(r) in the  U.S.
and  Japan  and of worldwide Factor VIII offerings (Monoclate-P(r),
Helixate(r) and Bioclate(r)).  Sales of Monoclate-P(r) were  higher
in  Europe but declined slightly in the U.S. due to increased sales
of the competitive recombinant brands, Helixate(r) and Bioclate(r).
In  the  first quarter of 1995, the Company initiated  a  voluntary
withdrawal of certain of its immune globulin offerings in the  U.S.
in  response to the FDA's industry-wide request that such  products
undergo a new testing technique.  In the third quarter of 1995, the
Company  received  FDA  approval  for  Gammar(r)  IV-P  pasteurized
immunoglobulin;   Gammar(r)  IV  experienced  third  quarter  sales
declines in anticipation of the fourth quarter 1995 launch  of  the
new pasteurized immunoglobulin offering.

Under  terms of a September 28, 1995 amendment to the Joint Venture
Agreement  (the  "Amendment"), the Company's Armour  Pharmaceutical
Company  subsidiary ("Armour") and Behringwerke AG  ("Behring"),  a
subsidiary  of Germany's Hoechst AG, completed the formation  of  a
50/50  global  joint venture in the plasma proteins business.   The
joint venture's Board of Directors will be formally established  on
January  1,  1996  at which time joint control and profit-  sharing
provisions will also take effect.

Improved  sales  of  central nervous system products  were  led  by
higher  sales of the sleeping agent Imovane(r)/Amoban(r) in  Europe
and Japan.  The French analgesic Doliprane(r) registered three- and
nine-month  sales  gains over comparable prior year  periods  which
were  affected  by  weak  demand.  In the  third  quarter,  an  FDA
advisory  committee  recommended the Company's product  Rilutek(tm)
(riluzole)  for U.S. FDA approval for the treatment of  Amyotrophic
Lateral  Sclerosis.  The recommendation will be considered  by  the
FDA  in  its  review  of  the Company's new  drug  application  for
Rilutek(tm).

Higher  sales  of  Azmacort(r) in the U.S. helped  generate  modest
sales  growth  of respiratory products for the three-month  period.
On  a  year-to-date basis, Azmacort(r) sales registered improvement
compared  to  a prior year period which was negatively affected  by
trade inventory reductions. The impact of a competitive entry  kept
current  year  Nasacort(r) sales below prior year  levels  for  the
quarter and nine-month periods.

Early in the fourth quarter of 1995, the Company acquired the U.K.-
based   pharmaceutical  company  Fisons  plc.   Of   Fisons'   1994
pharmaceutical   sales  which  totaled  $730  million,   sales   of
asthma/allergy products exceeded $500 million.  Management believes

                                17
<PAGE>
<PAGE>

that the acquisition of Fisons, which has established positions  in
the  U.S.,  Europe  and Japan, should result  in  a  strong  global
respiratory franchise.

Maalox(r)   recorded   solid   quarterly   and   nine-month   sales
improvements  in France and in Japan where Maalox(r) granules  were
launched  at  the end of 1994.  Although higher on  a  year-to-date
basis,  three-month  sales of Maalox(r) in Other  European  markets
were  slightly  below the prior year period  due,  in  part,  to  a
quarterly  decline  in  Germany.   In  January  1995,  the  Company
completed the transfer of its Canadian Maalox(r) product rights  to
Ciba-Geigy  Limited  ("Ciba");  the  Company's  U.S.  rights   were
transferred  to  Ciba in December 1994.  Reported  sales  for  1994
included  approximately $25 million and $69  million  of  U.S.  and
Canadian  Maalox(r)  sales for the three- and  nine-month  periods,
respectively.

Sales      growth     of    the     anti-inflammatory    Orudis(r)/
Profenid(r)/Oruvail(r)   was   spurred   by   quarterly   increases
in  South  American countries and in Japan.  Sales of Orudis(r)  in
European  markets  were  essentially level  quarter-on-quarter  and
remained  below  the  prior year on a nine-month  basis.  Increased
three-  and nine-month sales of bone metabolism products  reflected
continued  expansion of injectable and generic calcitonins  in  the
United States. In European markets, calcitonin sales remained below
the prior year levels.


                               18
<PAGE>
<PAGE>

Operating Income

                        Three Months ended September 30,
                     --------------------------------------
                           1995             1994 (Restated)    
                     ----------------      ----------------            
                               % of                  % of         Total
(in millions)          $       Sales         $       Sales        Change
                     -----   --------      ------   -------      -------
Gross margin         $793      65.4%        $741      65.1%          7%
Selling, delivery                                                  
  and administrative  422      34.8          408      35.8           3
Research and                                                       
  development         190      15.6          153      13.5          24
Operating income      182      15.0          180      15.8           1

                         Nine Months ended September 30,
                     ------------------------------------
                          1995            1994 (Restated)   
                     --------------       ----------------
                                % of                 % of     Total
(in millions)           $      Sales         $      Sales     Change
                     ------   ------      ------    ------    ------
Gross margin         $2,301    64.8%      $2,014     65.3%       14%
Selling, delivery                                                 
  and administrative  1,283    36.1        1,133     36.8        13
Research and                                                     
  development           533    15.0          430     13.9        24
Operating income        485    13.6          329     10.7        47

<PAGE>

Quarter-on-quarter   gross   margin  improvements   reflected   the
favorable   impact  of  price  and  product  mix-related  benefits.
Commercial expenses declined as a percentage of sales as the impact
of  reduced  advertising  and promotional  spending  offset  higher
selling  expenses, principally in the U.S. pharmaceuticals business
and  in  support  of the German and East/Central European  markets.
Quarterly   operating  income  margin  declined  as  an   increased
investment in research and development offset improved gross margin
and commercial expenses as a percentage of sales.

On  a  year-to-date basis, gross margin was negatively affected  by
unfavorable  product mix and the lower margin Cooper business;  net
change  in  price  had  a  favorable effect on  year-to-date  gross
margin.   Nine-month  selling, delivery and administrative  expense
ratios benefited from the absence in 1995 of higher advertising and
promotion costs associated with the Company's North American  over-
the-counter  businesses.  Excluding  the  effect  of   prior   year
restructuring charges, operating income margin declined  by  almost
one  percentage point due to reduced year-on-year gross margin  and
higher research and development expense as a percentage of sales.

In June 1994, the Company recorded a $121 million charge related to
a global restructuring plan.  For the three- and nine-month periods
ended  September 30, 1995, cash outlays associated  with  the  plan
approached  $9 million and $36 million, respectively; asset  write-
offs were not significant.  As of September 30, 1995, the Company's
workforce  had  been  reduced by just under 1,000  positions  as  a
result of the 1994 restructuring.

In  1993, the Company recorded charges of $94 million for the  cost
of  certain  restructuring and manufacturing streamlining  programs
and increased provisions for certain litigation.  Year-to-date cash
outlays  associated with the 1993 program exceeded $6 million.   As
of  September 30, 1995, over 650 positions had been affected by the
1993 plan.

Interest, Other Expense, and Taxes

Increased  net  interest expense for the quarter  reflected  higher
worldwide  average  debt  balances  in  support  of  acquired   new
businesses  and  higher  average  interest  rates.   Increased  net
interest  expense for the nine-month period was due principally  to
higher  average interest rates in the United States and in  certain
new  and/or  expanding markets including South America and  Eastern
Europe.

                                 19
<PAGE>
<PAGE>

During  the  third  quarter, the Company redeemed  its  outstanding
Market  Auction Preferred Shares ("MAPS"), resulting  in  a  slight
quarter-on-quarter  decline  in  preferred  dividends.    Increased
preferred dividends for the nine months of 1995 were due to  higher
short-term interest rates in the United States.

Gains on sales of assets totaling $50 million ($.25 per share) were
recorded  in  the first quarter of 1995.  These gains included  the
sale  of  assets related to the Company's Canadian over-the-counter
business  and  certain  European  product  rights.   Similar  gains
totaled $9 million ($.04 per share) in the comparable 1994 period.

Other  expense-net for the nine months of 1995 included charges  of
$38  million  ($.21  per  share) recorded  in  the  first  quarter,
including  $13  million ($.06 per share) of acquired  research  and
development expense related to an additional investment in  Applied
Immune  Sciences,  Inc. ("AIS") and $25 million  ($.15  per  share)
related  to  the  reassessment of the  carrying  value  of  certain
assets,  including  those  associated  with  the  Company's   prior
investment in The Immune Response Corporation.

The  Company's  year-to-date reported  effective  income  tax  rate
approximated  30% in 1995 compared with 27% in 1994.   The  current
year  rate  was affected by reduced tax benefits from  Puerto  Rico
operations  and  certain  asset sales/write-offs  while  the  prior
year's  effective tax rate was favorably impacted by  restructuring
charges.

Acquisitions

In October 1995, the Company gained operational control of the U.K.-
based pharmaceutical company Fisons plc via beneficial ownership of
a  majority  of Fisons' total share capital. By mid-November  1995,
RPR  had  completed  the acquisition of substantially  all  of  the
outstanding share capital of Fisons.  At 265 pence per  share,  the
aggregate purchase price will approximate $2.9 billion.

On  October 18, 1995, the Company announced a definitive  agreement
and  plan  of  merger  with AIS.  The agreement  provides  for  the
acquisition  by RPR of the seven million AIS shares not  previously
owned  by RPR at a cash price of $11.75 per share, or approximately
$84  million.  Subject to certain events and conditions, the tender
offer and merger are expected to be completed by the end of 1995.


Financial Condition

Cash Flows

Operating activities provided cash of $276 million during the nine-
month  period  of 1995 as compared with $412 million in  the  prior
year.   Lower 1995 operating cash flows reflected increased working
capital  needs and higher cash outlays for restructuring activities
and   income   taxes.    Year-to-date  cash  outlays   related   to
restructuring activities totaled $42 million.  Income tax  payments
for  the  nine  months  included a $42 million  first  quarter  tax
payment related to the Ciba transaction.

                               20
<PAGE>
<PAGE>

Current  year investing activities included cash outflows  of  $185
million  related to the acquisition of new businesses, including  a
Brazilian  pharmaceutical  business formerly  owned  by  RP  and  a
generics company in France. Cash outflows also included $80 million
associated  with certain investments in technologies including  $43
million  in  the  first  half of 1995 for the  acquisition  of  two
million  common shares of AIS, and payments of $41 million  related
to  the purchase of certain product rights.  Proceeds from sales of
assets,  including  the sales of the Company's  Canadian  over-the-
counter  business and certain European product rights, totaled  $85
million.  Nine-month capital expenditures exceeded comparable  1994
spending by $48 million.

Financing   activities  provided  cash  inflows  of  $69   million.
Increased  borrowings, primarily in support of businesses  acquired
and to finance preferred share redemptions totaled $424 million for
the  nine-month  period.  Cash outflows associated with  the  third
quarter  redemption of MAPS Series A, C and D totaled $225 million.
Cash  dividends paid to common shareholders were $137 million ($.90
per  share) as compared with $128 million in 1994 ($.84 per share).
In  October 1995, the Board of Directors declared a fourth  quarter
cash  dividend  of  $.30 per share payable  November  30,  1995  to
holders  of  record  on  November 10, 1995. Cash  outlays  of  $216
million  in 1994 included open market common share repurchases  for
the Employee Benefits Trust totaling $109 million.

                               21
<PAGE>
<PAGE>

Liquidity

The  Company's net debt (short- and long-term debt including  notes
payable   to   RP,  less  cash  and  cash  equivalents,  short-term
investments  and  time  deposits) to net  debt  plus  equity  ratio
increased  to  .34  to 1 at September 30, 1995 from  .16  to  1  at
December  31, 1994 principally as a result of increased borrowings.
The  ratio of current assets to current liabilities was 1.55  to  1
compared to 1.40 to 1 at December 31, 1994.

At  September 30, 1995, the Company had committed lines  of  credit
totaling $5.2 billion with approximately $100 million of borrowings
outstanding  under these lines. Of the $5.2 billion,  $4.3  billion
represented loan facility agreements effective August 17, 1995 with
Banque  Nationale  de  Paris ("BNP"), Credit Lyonnais  and  Societe
Generale.   Drawings  under  these  facilities,  which  mature   in
February  1996, bear interest at the London Interbank Offered  Rate
("LIBOR")  plus a margin. These arrangements temporarily  suspended
certain  other line of credit agreements previously in  place  with
the  same  banks totaling $680 million; the suspended  amounts  are
reestablished  upon the maturity of the August 17th facilities  and
will expire in the year 2000.  Of the remaining $.9 billion of  the
total  $5.2  billion committed lines of credit at  September  30th,
$400  million  related  to  a long-term revolving  credit  facility
unconditionally guaranteed by RP; this facility was  terminated  on
October  25, 1995. The remaining $500 million consisted of  new  or
renegotiated  medium-term multicurrency line of  credit  agreements
expiring  in  the  next  five years.  At September  30,  1995,  the
Company  had the ability and intent to renew or to refinance  under
its facilities approximately $635 million of short-term third party
borrowings  for  at least one year.  Accordingly, this  amount  was
classified as long-term debt.

By  mid-November 1995, RPR had completed the purchase of 93% of the
outstanding  shares of Fisons for approximately $2.7  billion.   Of
this  amount, $1.75 billion was financed under the Societe Generale
and  BNP loan facility arrangements; $700 million, the majority  of
which  represented open market share purchases, was financed  under
short-term  loan arrangements with certain banks;  a  further  $250
million represented drawdowns of the Company's medium-term lines of
credit.  The weighted average annual effective interest rate on the
$2.7  billion of new borrowings approximated 6.1%.  These  drawings
mature  in  December  1995 at which time  the  Company  intends  to
establish longer-term financing arrangements.

The   sale  of  Fisons'  Laboratory  Supplies  Division  to  Fisher
Scientific  International Inc. for $310 million  was  completed  in
October  1995.  Sale of Fisons' Scientific Instruments Division  to
Thermo  Instrument  Systems Inc. for $318  million  is  subject  to
regulatory approval and will not be completed in 1995.

In  October 1995, the Company announced a definitive agreement  and
plan  of merger with AIS, providing for the acquisition by  RPR  of
the  remaining  shares of AIS not owned by  RPR  at  a  cash  price
approximating  $84  million. The transaction,  when  finalized,  is
expected to be financed under available medium-term lines of credit
bearing interest at an annual rate of LIBOR plus a margin.

Pursuant  to a shelf registration, the Company has the  ability  to
issue  an additional $325 million in public debt securities  and/or
preferred shares.

                                  22
<PAGE>
<PAGE>

In October 1995,  Moody's Investor Service ("Moody's") and Standard
&  Poor's  ("S&P") lowered the Company's senior unsecured debt  and
preferred  share  credit ratings, attributing  the  change  to  the
acquisition of Fisons.  The Company's senior unsecured debt is  now
rated  Baa1  by  Moody's and BBB by S&P.  The  Company's  preferred
shares are rated Baa2 by Moody's and BBB- by S&P.

Management  believes that cash flows from operations,  supplemented
by  financing expected to be available from external sources,  will
provide  sufficient liquidity to meet its needs for the foreseeable
future.   Long-term  liquidity  is  dependent  upon  the  Company's
competitive  position, including its ability to  discover,  develop
and  market  innovative new therapies and maximize the benefits  of
new   business  alliances.   The  Company  routinely  explores  new
strategic business alliances as such opportunities arise.

The Company is involved in litigation incidental to its business.
A discussion of contingencies appears in Note 10 of the Notes to
Condensed Consolidated Financial Statements and in Legal
Proceedings in Part II of this Form 10-Q.

                             23
<PAGE>
<PAGE>
                  PART II.    OTHER INFORMATION


ITEM 1.   LEGAL PROCEEDINGS


Diethylstilbestrol ("DES") Litigation

There are approximately two hundred and fifty legal actions
pending against one or more subsidiaries of the Company and
various groupings of more than one hundred pharmaceutical
companies, in which it is generally alleged that "DES daughters"
and/or their offspring were injured as a result of the
development of various reproductive tract abnormalities in the
"DES daughters" because of their in utero exposure to DES.
Typically, William H. Rorer, Inc. ("WHR") and Kremers-Urban
Company ("K-U"), two former operating subsidiaries of the
Company, are named as defendants, along with numerous other
former DES manufacturers, when the claimant is unable to
identify the manufacturer of the DES to which she was exposed.
While the aggregate monetary damages sought in all of these DES
actions are substantial, the Company believes that both WHR and
K-U have adequate defenses to DES claims.  In May 1994, a
proposed class action was filed on behalf of persons alleging
injuries caused by DES and living in the state of Ohio (Kurczi,
                                                       --------
et al. v. Eli Lilly, et al., United States District Court for
- ---------------------------
the Northern District of Illinois).  The Company and certain of
its current and former subsidiaries were named among the 192
defendants.  Class certification was denied in February 1995.
All pending cases are currently being defended by insurance
carriers, sometimes under a reservation of rights.

AHF Litigation

There are approximately three hundred and eleven lawsuits in the
United States, six in Canada and fifty-six in Ireland pending
against the Company's Armour Pharmaceutical Company ("Armour")
subsidiary, and in some instances, the Company and certain of
its other subsidiaries, in which individuals with hemophilia and
infected with the Human Immunodeficiency Virus ("HIV"), or their
representatives, claim that such infection and, in some cases,
resulting illnesses, including Acquired Immune Deficiency
Syndrome-related conditions or death therefrom, may have been
caused by administration of anti-hemophilic factor ("AHF")
concentrates processed by Armour in the early and mid-1980s.
None of these cases involves Armour's currently distributed AHF
concentrates.  In most of these suits, Armour is one of a number
of defendants, including other fractionators who supplied AHF
during that period.  To date, approximately one hundred and four
cases and claims have been resolved either by dismissal by the
plaintiffs or the Court or through settlement.  A majority of
the currently pending lawsuits were filed in 1993, and
management expects additional lawsuits will be filed.  It is not
possible, however, to predict with certainty the number of
additional lawsuits that may eventually be filed alleging HIV-
related claims.

In January 1993, a jury in Florida held that Armour was liable
to the parents of a deceased HIV-infected hemophiliac for
damages of approximately $2 million.  Armour believed this
verdict to be inconsistent with evidence specific to the case
and, accordingly, filed motions with the trial court seeking
reversal or, alternatively, a new trial.  The trial court denied

                               24
<PAGE>
<PAGE>

both motions and Armour  appealed the judgment to the United
States Court of Appeals for the Eleventh Circuit.  In June 1995,
the Court of Appeals issued an opinion reversing the verdict and
remanding the case for a new trial because of prejudicial error
in the district court's instruction concerning the learned
intermediary doctrine.  The court affirmed in respect to
Armour's contentions regarding an absence of sufficient evidence
of causation.  Both parties' petitions for rehearing were
denied, and the case has been returned to the district court for
retrial.  Regardless of the ultimate outcome of this case, and
because the facts vary widely in such cases, the Company does
not view a possibly adverse verdict as predictive of, or as
precedent for, decisions in any other cases.  Juries in other
AHF cases have determined that Armour and the other plasma
fractionators acted responsibly and were not negligent.  In
October 1993, Armour obtained a directed verdict dismissing it
from a lawsuit pending in Louisiana State Court on the basis
that the plaintiff had not presented evidence sufficient to
maintain an action against Armour.  That decision has been
appealed by plaintiff to the state appellate court in Louisiana
and was argued in March 1995.  Additionally, in November 1993, a
jury verdict in favor of Armour and the other plasma
fractionators was obtained in an action pending in the United
States District Court for the Northern District of Illinois.
The jury concluded that the fractionators of Factor VIII
concentrate in the early 1980s were not negligent as alleged and
accordingly were not liable to the claimant.  In March 1995, the
United States Court of Appeals for the Seventh Circuit granted
the plaintiffs' appeal in this action and remanded the case for
a new trial because of improper closing argument by counsel for
one of the defendants.  Subsequent to the issuance of the
court's opinion in March, Armour reached an out of court
settlement with the plaintiffs.  Armour reasonably expects that
other cases may proceed to trial in the future.

In December 1993, the Federal Multi-District Litigation Panel
("MDL") authorized the consolidation of all AHF litigation
pending in U.S. Federal Courts for purposes of pre-trial
discovery and the transfer of such cases to the U.S. District
Court for the Northern District of Illinois for this purpose.
Four proposed federal class action lawsuits (Wadleigh, et al. v.
                                            --------------------
Armour Pharmaceutical Company, et al., United States District
- -------------------------------------
Court, Northern District, Illinois; Richard Roe and his mother,
                                    ---------------------------
Jane Roe v. Armour Pharmaceutical Company, et al., United States
- -------------------------------------------------              
District Court, Idaho District; Jose Alvarez, Jr. et al. v.
                                ---------------------------
Armour Pharmaceutical Company, et al., United States District
- -------------------------------------
Court for the Eastern District of Louisiana; and Timmy Dale
                                                 ----------
Martin, et al. v. Armour Pharmaceutical Company, et al. United
- -------------------------------------------------------
States District Court for the Northern District of Alabama), and

two proposed state class actions (Jeffrey Stanger, et al. v.
                                 ---------------------------
Armour Pharmaceutical Company, et al., Superior Court, Pima
- -------------------------------------
County, Arizona and Jones v. Bayer Corporation et al, Florida),
                    --------------------------------
discussed further below, have been filed against several
fractionators, including Armour.  The federal actions are part
of the MDL proceeding in Chicago.

In an August 1994 bench ruling  and  Memorandum Opinion, the
Court in Wadleigh stated that it intended to certify the issue
         --------
of negligence in that action for class action treatment, but
that it would deny plaintiffs' motion for certification of an
all-purpose class action and plaintiffs' motion for
certification of the issues of strict liability, breach of
warranty, proximate cause, and punitive damages.  In September
1994, the Court denied the defendants' motion for
reconsideration, and also denied defendants' request that it
certify the issues for immediate consideration by the Court of
Appeals.  In an order entered in October 1994, the Court ruled
that it would not certify plaintiffs' concert of action claim
for class treatment.  In November 1994, the Court entered its
formal class certification order, and in December 1994 entered
further orders regarding notice to the class and also denied
class certification in the federal actions other than Wadleigh.
                                                      --------
Under the issue certification contemplated by the Court in
Wadleigh, only the issue of negligence would be tried on a class-
- --------

                             25
<PAGE>
<PAGE>

wide basis.  In the event of a defense verdict, all class
members would be bound thereby; in the event of a plaintiffs'
verdict, it would be necessary for each class member to attempt
to utilize that favorable outcome in his own separate
litigation.  The class trial would not involve any issues of
causation or damages, or a determination as to any defenses such
as the statute of limitations.

As the facts in each individual lawsuit varied widely, Armour
did not believe that class action status was warranted in the
Wadleigh action.  In December 1994, Armour and the other
- --------
fractionator/defendants in Wadleigh filed a petition for a writ
                           --------
of mandamus in the Seventh Circuit Court of Appeals in Chicago
seeking to have the class certification order vacated.  In March
1995, the Court of Appeals granted the writ of mandamus in a two-
to-one decision and directed the District Court to decertify the
plaintiff class.  The plaintiffs thereafter filed a petition for
rehearing and suggestion for rehearing en banc with the Court of
                                       -- ----
Appeals.  Plaintiffs' petition for rehearing was denied in April
1995.  In June 1995, the Court of Appeals on plaintiffs' motion
entered an order staying its mandate so as to permit the
plaintiffs to seek a writ of certiorari from the United States
Supreme Court.  In July  1995, plaintiffs filed their petition
for a writ of certiorari with the U.S. Supreme Court.  In
October 1995, the Supreme Court denied plaintiffs' petition.  As
a result, the negligence class previously certified by the
District Court in Wadleigh will be decertified.
                  --------

As noted above, in May 1995, an additional "nationwide" class
action (Jones) was filed in the Florida state court against the
        -----
same defendants as in Wadleigh, together with a Florida plasma
                      -------- 
provider; plaintiffs' counsel consist of a subgroup of counsel
from Wadleigh.  Defendants have removed the action to federal
     --------
court. Plaintiffs' motion to remand the action to the state
court is pending.

In the U.S., Armour and other plasma fractionators have
participated in discussions with representatives of the
hemophilia community, including the National Hemophilia
Foundation, concerning the issue of assistance for U.S.
hemophiliacs infected with HIV.  In August 1994, Armour and
Baxter Healthcare Corporation ("Baxter") reached a tentative
settlement with attorneys representing claimants in the
purported class-action lawsuits pending against the respective
companies and submitted a Memorandum of Understanding to the
Court in that regard.  However, as a result of the Court's
statements with respect to class certification in Wadleigh,
                                                  --------
plaintiffs' counsel withdrew their recommendation concerning the
settlement.  Armour will continue to vigorously defend its
position in all cases and claims brought against it.

With respect to this litigation, the Company has contractual
rights to certain insurance coverage provided by carriers that
provided insurance to Revlon, Inc., the party from which it
purchased the Armour business in 1986 ("Revlon carriers").  The
Company also believes that it has access to "excess" liability
insurance coverage from other carriers, effective in 1986, for
certain of these cases if certain self-insured retention levels
from relevant insurable losses are exceeded.

The Company has been involved in litigation with a principal
insurance carrier ("the principal carrier") and an umbrella
insurance carrier ("the umbrella carrier"), as well as with
certain of the Revlon carriers, relative to carrier defense and
indemnity obligations associated with AHF litigation ("the
insurance coverage litigation").   In late 1994, the Company
settled the dispute being litigated with the principal carrier
by entering into an agreement which defines the principal
carrier's obligations with respect to the underlying AHF
litigation.  The Company has also settled its disputes with the

                          26
<PAGE>
<PAGE>

umbrella carrier and certain of the Revlon carriers.  Recently,
after lengthy discussions, the Company and the remaining Revlon
carriers in the insurance coverage litigation reached an
agreement in principle regarding the extent and other conditions
of coverage of those carriers.  Based upon the above, the
Company believes that, although not a certainty, a substantial
level of coverage (including substantial coverage for legal
defense expenditures) for the Company's estimated liability
determined in accordance with Statement of Financial Accounting
Standards No. 5 ("SFAS 5") is probable of occurrence.

Certain Contract Litigation

Rhone-Poulenc Rorer Pharmaceuticals Inc. ("RPRP"), a subsidiary
of the Company, has been named as a defendant in two related
breach of contract lawsuits initiated by Boehringer Mannheim
GmbH and its American affiliate, Boehringer Mannheim
Pharmaceuticals Corporation (collectively, "BM"), seeking
compensatory damages.  Specifically, BM commenced arbitration
proceedings in Switzerland and litigation in the state court of
Maryland alleging that RPRP breached an agreement related to the
development of BM's bisphosphonate compound and a copromotion
agreement pertaining to the Company's licensed product Lozol(r).
RPR filed a counterclaim in the Maryland litigation against BM
for fraud related to representations made by BM and its agents
prior to the execution of the agreements.  In March 1995, the
parties agreed to dismiss the Maryland litigation and to
transfer all of those claims to final and binding arbitration in
Switzerland.  At present, two arbitration proceedings before the
same panel are underway.  The Company believes that the claims
asserted by BM are without merit and RPRP intends to vigorously
defend its position.

Antitrust Litigation

The Company has been named as a defendant in 121 antitrust
lawsuits.  It is presently a party to eight state court actions
pending in California, and one each in Wisconsin, Alabama,
Washington, Minnesota, Colorado and New York.  Additionally, the
Company has been named in 107 antitrust actions brought in
several federal courts which have been coordinated before a
judge in the U. S. District Court for the Northern District of
Illinois (Chicago).  Seven of the cases brought in California
state court have similarly been coordinated before a judge in
the San Francisco Superior Court; defendants have moved to
coordinate the recently filed eighth case in San Francisco
Superior Court with the other cases.  The suits allege that
certain pharmaceutical companies (including RPR) and
wholesalers, in conjunction with certain pharmacy benefits
managers, discriminated against independent community pharmacist
plaintiffs and/or retail chains with respect to the prices
charged for brand name pharmaceutical products and further
conspired to maintain prices at artificially high levels to the
detriment of these pharmacies.  One of the California actions
alleges injury to a class of California residents who are
consumers of brand name prescription products.  The cases in New
York, Colorado and Washington allege proposed consumer class
claims.  On October 4, 1995, the Washington state court action
was dismissed with prejudice with the court holding that
Washington law did not permit a consumer action in this
instance.  Many of the federal actions were brought on behalf of
an alleged class of retail pharmacies throughout the United
States; three of the state cases similarly allege classes of
pharmacists within those states.  Plaintiffs in these lawsuits
seek injunctive relief and a monetary award for past damages
alleged.  The federal class plaintiffs have filed an amended
consolidated Complaint so that issues affecting the class are
pleaded consistently.  The coordinating federal court certified
the class alleged in the amended consolidated Complaint in

                                27
<PAGE>
<PAGE>

November 1994.  Notice to the class was given and the opt-out
period ended March 10, 1995.  The coordinating California state
court certified retail and consumer classes in June 1995.
Notice to the class has not yet been provided.

The Company believes that these claims are without merit and it
intends to vigorously defend these lawsuits.

Patent and Intellectual Property Litigation

In February 1993, Tanabe Seiyaku Company ("Tanabe") of Japan and
their U.S. licensee, Marion Merrell Dow Inc. ("MMD") initiated
an action before the International Trade Commission ("ITC"), the
administrative agency responsible for handling complaints of
imports which allegedly infringe U.S. intellectual property
rights.  The complaint names ten domestic and foreign
respondents, including the Company, and alleges infringement of
a Tanabe U.S. patent, claiming a process for preparing bulk
diltiazem, the active ingredient in the Company's Dilacor(r) XR
product.  In January 1995, the ITC Administrative Judge ruled
that Dilacor(r) XR does not infringe the MMD/Tanabe patent under
any circumstances and that the MMD/Tanabe patent is invalid and
unenforceable.  An appeal was taken and the Commission
effectively affirmed the ITC Judge's rulings on invalidity,
unenforceability and noninfringement findings.  MMD/Tanabe has
appealed to the Court of Appeals for the Federal Circuit.

The Company is a plaintiff in a patent infringement lawsuit with
Chiron Corporation filed in the United States District Court in
California involving the patent licensed exclusively to the
Company by the Scripps Research Institute ("Scripps") covering
the anti-hemophilic Factor VIII:C.  The Court is considering
pending summary judgment motions.  If this case goes to trial,
such trial is likely to be scheduled to commence within the six
to twelve months after the Court's decision on the summary
judgment motions.

The eventual outcomes of the above matters of pending litigation
cannot be predicted with certainty.  The defense of these
matters and the defense of expected additional lawsuits related
to these matters may require substantial legal defense
expenditures.  The Company follows SFAS 5 in determining whether
to recognize losses and accrue liabilities relating to such
matters.  Accordingly, the Company recognizes a loss if
available information indicates that a loss or range of losses
is probable and reasonably estimable.  The Company estimates
such losses on the basis of current facts and circumstances,
prior experience with similar matters, the number of claims and
the anticipated cost of administering, defending and, in some
cases, settling such claims.  The Company has also recorded as
an asset, insurance recoveries which are determined to be
probable of occurrence on the basis of the status of current
discussions with its insurance carriers.  If a contingent loss
is not probable, but is reasonably possible, the Company
discloses this contingency in the notes to its consolidated
financial statements if it is material.  Based on the
information available, the Company does not believe that
reasonably possible uninsured losses in excess of amounts
recorded for the above matters of litigation would have a
material adverse impact on the Company's financial position,
results of operations or cash flows.

                                  28
<PAGE>
<PAGE>

ITEM 6.   Exhibits and Reports on Form 8-K

a. Exhibits

     10   Material contracts.
          (a)  $200,000,000 Loan Facility Agreement with Banque
               Nationale de Paris dated June 15, 1993 ("BNP Agreement").
          (b)  First Supplemental Agreement to the BNP Agreement
               dated April 13, 1995.
          (c)  Amendment No. 2 to the BNP Agreement effective
               August 17, 1995.
          (d)  $1,100,000,000 Loan Facility Agreement with
               Societe Generale effective August 17, 1995.
          (e)  $1,500,000,000 Loan Facility Agreement  with
               Credit Lyonnais effective August 17, 1995.

     11   Statement re computation of earnings per common share.

     15   Letter re unaudited interim financial information.


b. Reports on Form 8-K

     The Company filed the following Current Reports on Form 8-K:

- -    Current Report on Form 8-K dated August 14, 1995 containing
     the restated financial statements for the year ended
     December 31, 1994 resulting from the Cooper and Brazilian
     business acquisition transactions.
     
- -    Current Report on Form 8-K dated August 17, 1995 containing
     the Company's press release announcing a cash offer for
     Fisons plc and disclosing additional loan facility
     arrangements.
     
- -    Current Report on Form 8-K dated September 28, 1995
     announcing the creation of the joint venture between Armour
     Pharmaceutical Company and Behringwerke AG.
     
- -    Current Report on Form 8-K/A (Amendment to Form 8-K dated
     September 28, 1995) containing Behringwerke AG historical
     combined financial statements and company pro forma
     financial information.
     
- -    Current Report on Form 8-K dated October 5, 1995 containing
     the Company's press releases announcing a final cash offer
     for Fisons plc, certain open market purchases of Fisons'
     ordinary shares, and the recommendation of the offer by
     Fisons' Board to its shareholders.
     
- -    Current Report on Form 8-K dated October 18, 1995
     containing the press release announcing a definitive
     agreement and plan of merger between the Company and
     Applied Immune Sciences, Inc.

                             29
<PAGE>
<PAGE>
     
- -    Current Report on Form 8-K dated October 20, 1995
     containing the Company's press releases declaring the
     Company's offer for Fisons plc unconditional and announcing
     beneficial ownership over 90%.


                             30
<PAGE>
<PAGE>



                               SIGNATURES







     Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed
on its behalf by the undersigned thereunto duly authorized.





                               RHONE-POULENC RORER INC.
                               -------------------------
                               (Registrant)





    November 14, 1995     /s/  PATRICK LANGLOIS
  --------------------  -------------------------------
                               Patrick Langlois
                               Senior Vice President and
                               Chief Financial Officer





                              31
<PAGE>
<PAGE>

                           INDEX TO EXHIBITS





Exhibit No.
- -----------

 10             Material contracts.
                   (a) $200,000,000 Loan Facility Agreement
                       with Banque Nationale de Paris
                       dated June 15, 1993 ("BNP Agreement").
                   (b) First Supplemental Agreement to the BNP
                       Agreement dated April 13, 1995.
                   (c) Amendment No. 2 to the BNP Agreement
                       effective August 17, 1995.
                   (d) $1,100,000,000 Loan Facility Agreement with
                       Societe Generale effective August 17, 1995.
                   (e) $1,500,000,000 Loan Facility Agreement  with
                       Credit Lyonnais effective August 17, 1995.

 11             Statement re computation of earnings
                per common share.

 15             Letter re unaudited interim financial
                information.




                                   32



                                                  Exhibit 10(a)

TRANSLATION FOR INFORMATION PURPOSES ONLY

BETWEEN:

- -  BANQUE NATIONALE DE PARIS or BNP, a "societe anonyme" with a
share capital of FF 3,536,972,150, whose registered office is at
16 Boulevard des Italiens, 75009 PARIS, registered with the
PARIS Registry of Commerce and Companies under number B 662 042
449,

represented by:

- -  Mr Ervin ROSENBERG, Manager
- -  Mr Alain CHANTEREAU, Assistant Manager

(the "Bank", if not referred to by name)

                                   OF THE ONE PART,

AND:

- -  RHONE-POULENC RORER INC, a limited liability company with a
share capital of USD 438,298,771, whose registered office is at
500 Arcola Road, COLLEGEVILLE, PENNSYLVANIA 19426, UNITED STATES
OF AMERICA,

represented by:

- -  Mr Patrick LANGLOIS
  Corporate Senior Vice President, Chief Financial Officer

(the "Borrower", if not referred to by name)

                                   OF THE OTHER PART,
<PAGE>
<PAGE>

IT IS AGREED AS FOLLOWS:

ARTICLE I - AMOUNT AND PURPOSE OF LOAN

The Bank agrees to grant the Borrower a loan facility (the
"Loan") of a maximum amount of USD 200,000,000 (TWO HUNDRED
MILLION US DOLLARS) or its equivalent in FRF, DEM or GBP.

The Loan is entered into in order to reinforce the Borrower's
financial resources.

Subject to the prior written agreement of RHONE-POULENC RORER
INC, the following companies, being subsidiaries owned as to
more than 50% by RHONE-POULENC RORER INC:

- -  RHONE-POULENC RORER S.A.
- -  RHONE-POULENC RORER LTD
- -  RHONE-POULENC RORER GmbH

may make drawings under the Loan subject to the guarantee by
RHONE-POULENC RORER INC in the form attached as schedule I
hereto.

Subject to the prior written agreement of RHONE-POULENC RORER
INC, RHONE-POULENC S.A. may make drawings under the Loan.

RHONE-POULENC S.A., RHONE-POULENC RORER S.A., RHONE-POULENC
RORER LTD and RHONE-POULENC RORER GmbH shall, prior to the first
drawing that they may make, enter into an undertaking directly
with the Bank on the terms of schedule II to this loan
agreement. The terms and conditions agreed with RHONE-POULENC
RORER INC shall apply to these companies.

RHONE-POULENC RORER INC, RHONE-POULENC RORER S.A., RHONE-POULENC
RORER LTD, RHONE-POULENC RORER GmbH and RHONE-POULENC S.A. shall
hereafter be referred to as the "Borrowing Companies".

<PAGE>
<PAGE>

ARTICLE II - DURATION OF THE LOAN

The Loan is granted for a period of four years from 15th June,
1993 to 15th June, 1997.

ARTICLE III - REPAYMENT

Except in the case of prepayment under Article VIII ("PREPAYMENT
FACILITY"), the Loan shall be repaid in one single instalment on
15th June, 1997.

ARTICLE IV - METHODS OF DRAWING

Drawings may be made under this loan on one business day's
notice in respect of drawings in FRP and two business days'
notice in respect of drawings in USD, GBP or DEM, by the
debiting of a special account constituting a simple accounting
record, which shall not have the legal consequences of a running
account and which shall be opened for these purposes by each of
the Borrowing Companies in the books of the BNP LA DEFENSE
Branch. Drawings shall have a duration of one, two, three or six
months. However, drawings in French francs may have a minimum
duration of fifteen days.

RHONE-POULENC RORER INC shall also be able to make drawings in
USD without prior notice through BNP NEW YORK.

In respect of drawings in French francs, the Borrowing Companies
shall draw one or more notes in favour of the Bank payable at
BANQUE NATIONALE DE PARIS, which shall include a provision that
the bearer of the note is not required to protest the notes at
their maturity.

The amount of drawings in currencies other than US Dollars shall
be calculated on the basis of the rate of exchange of the US
Dollar against the relevant currency, on the PARIS Foreign
Exchange Market, two business days before the drawing date (one
business day in the case of drawings in French francs).

<PAGE>
<PAGE>

"Business day" means any complete day on which the banks are
open:

- -  in respect of drawings in French francs, in PARIS;

- -  in respect of drawings in euro-currencies, in LONDON and the
principal national financial centre of the currency in which the
drawing is made.

After having drawn on the Loan and reimbursed it in one or more
instalments, in whole or in part, the Borrowing Companies may
request new drawings, subject to the limits relating to amount
and duration set out herein.

The drawings as well as subsequent renewals and prepayments, if
any, shall be made in accordance with the provisions of the
Exchange Control Regulations ("Reglementations des Changes")
that may apply to such transactions.

ARTICLE V - NON-AVAILABILITY OF CURRENCY

If the Bank observes, at the time of either any drawing or a new
interest period, that the currency is not available on the PARIS
inter-bank market, it shall notify the Borrowing Companies
thereof as soon as possible.

In such a situation, the parties shall consult in order to reach
an agreement on the replacement currency or on a possible
reversion to French francs. Failing agreement between the
parties, the drawing or the renewal shall not take place.
Existing drawings in the non-available currency shall then be
repaid in French francs by the drawing company or companies as
regards principal, interest, costs and expenses (if any)
incurred by the Bank by reason of the non-availability of the
currency. The Bank agrees to supply evidence of these costs,
incidental expenses and possible costs on demand by the
Borrowing Companies.

<PAGE>
<PAGE>

The amount in FRF to be repaid shall be determined according to
the most recent quotation of the rate for the currency in which
the loan was then denominated.

ARTICLE VI - CONTROL OF THE EQUIVALENT AMOUNT IN USD OF THE
OUTSTANDING AMOUNT

The total amount of drawings shall not exceed the equivalent of
USD 200,000,000 (TWO HUNDRED MILLION US DOLLARS) (the "Original
Amount") reduced by repayments that shall already have been
made. The US dollar equivalent of the drawings shall be verified
at the time of each drawing or at the beginning of each interest
period at the exchange rate in force on the day of the
verification.

If the US dollar equivalent is larger by 5% than the Original
Amount reduced by repayments already made, the Bank shall only
renew the outstanding amount for a sum in foreign currencies
corresponding to the equivalent amount of the Original Amount
expressed in USD reduced by repayments already made, and the
drawing company or companies shall repay the difference thus
calculated.

However, if this equivalent is not larger by 5% than the
Original Amount expressed in USD reduced by repayments already
made, the Bank shall renew the outstanding amount in foreign
currencies at its previous level.

ARTICLE VII - CONDITIONS

- -  COMMITMENT FEE:

0.20% per annum payable half-yearly in advance on the authorised
amount irrespective of any drawings.

This fee shall, in any event, be borne by RHONE-POULENC RORER
INC, which shall secure the division thereof between the
Borrowing Companies. It shall be calculated on the basis of a
360-day year and shall be payable in US dollars.

<PAGE>
<PAGE>

- -  INTEREST:

- -  in respect of drawings or renewals of drawings in FRF:

  Interest shall be calculated according to the precise number
of days in the relevant period as compared with 360 days at the
PIBOR rate (PARIS INTERBANK OFFERED RATE) for the selected
period of drawing or renewal or the next longest period shown at
11.00 a.m. on the Business Day preceding the date of drawing or
renewal on TELERATE page 20041 or any other page substituted
therefor, increased by 0.25% annum.

  The above interest shall be paid at the end of each interest
period.

- -  in respect of drawings or renewals of drawings in foreign
currencies:

  Interest shall be calculated according to the precise number
of days in the relevant period as compared with 360 days for all
currencies, with the exception of GBP, interest in respect of
which shall be calculated as compared with 365 days.

  Interest shall be determined according to the LIBOR rate
(LONDON INTERBANK OFFERED RATE) for the relevant currency for
the selected period of drawing or renewal for sums equivalent to
those advanced, calculated under the aegis of the BRITISH
BANKERS ASSOCIATION and shown on TELERATE - Page 3750 or any
other page substituted therefor at 11.00 a.m. (LONDON time), two
business days before the drawing date or the beginning of a new
interest period, increased by 0.25% per annum.

  In the case of drawings made by RHONE-POULENC RORER INC in USD
without prior notice through BNP NEW YORK, interest shall be

<PAGE>
<PAGE>

determined according to the cost of funds of BNP NEW YORK for
the selected drawing or renewal period, increased by 0.25% per
annum.

  The above interest shall be payable at the end of each
interest period.

The Bank shall notify the Borrowing Company of the rate of
interest applicable to the relevant interest period. This rate
shall be revised at the end of each interest period.

The special account referred to above in Article IV "METHODS OF
DRAWING" shall be exempt from the payment of any account fee and
any fee on the largest overdraft outstanding thereon. Interest
shall automatically be debited to the current account maintained
on the books of the BNP LA DEFENSE Branch by each of the
Borrowing Companies.

If the determination of an interest rate has become impossible
by reason of the occurrence of certain events, the Bank shall
notify the Borrowing Companies of such fact, and the parties
shall enter into negotiations. If no agreement is reached with a
view to a solution within 30 days of this notification, the
Borrowing Companies shall repay the Loan as to principal
interest, costs, incidental expenses and costs (if any) provided
that the applicable interest rate shall be the Bank's own cost
of financing, increased by 0.25% per annum.

Any sum not paid on its contractual or accelerated maturity date
shall automatically bear interest for the period from and
including such maturity date until but excluding the day of full
payment, at the rate applied during the preceding drawing or
renewal period, increased by 1% per annum.

Interest outstanding for a whole year shall be capitalised in
accordance with Article 1154 of the Civil Code.

These provisions do not constitute consent to late payment.

<PAGE>
<PAGE>

For the purposes of article 4 of the Law of 28th December, 1966
relating to notice of global effective rates, it is hereby
provided that, taking account of the three-month LIBOR rate for
US dollars on 9th June, 1993 and a commitment fee payable half-
yearly in advance, a full drawing of this loan on 10th June,
1993 would have resulted in a rate of 3.83%.

ARTICLE VIII - PREPAYMENT FACILITY

Each of the Borrowing Companies may cancel the Loan or prepay
it, in whole or in part, at the end of any current drawing
period, provided that it gives the Bank at least 30 (thirty)
days' notice by registered letter with postal acknowledgment of
receipt of its irrevocable intention to terminate or to repay
the loan, in whole or in part.

Any termination or prepayment shall be final for the relevant
Borrowing Company.

The commitment fee shall cease to be due on that part of the
loan in respect of which the Borrower shall have given such
notice as from the end of the half-yearly commitment fee period
during which the cancellation shall have taken effect.

ARTICLE IX - ACCELERATION OF MATURITY

A/  The Bank reserves the right to declare the acceleration of
all the sums due from any of the Borrowing Companies as regards
principal, interest, default interest, fees, costs and expenses
and no further drawing may be made by such Company in the
following circumstances:

1)   if RHONE-POULENC RORER INC reduces its direct or indirect
shareholding in the share capital of such Company such that it
becomes a subsidiary that is less than 50% owned (this clause
shall not apply to RHONE-POULENC S.A.),

<PAGE>
<PAGE>

2)   if payment is not made by such Company of any sum due under
the Loan on its due date, and such default is not made good
within fifteen days of receipt of a notice from the Bank to the
Company by registered letter,

3)   if payments are not made by such Company on their due dates
of sums due to any party under other borrowings, and such
default in payment has caused the acceleration of such
borrowings. Acceleration shall not be declared if the debt is
validly disputed or if the sums involved are of a nominal amount
of less than USD 10m (USD 30m so far as RHONE-POULENC S.A. is
concerned), or its equivalent,

4)   if such Company does not comply with any of its other
obligations undertaken under the Loan or if a written warranty
made by such Company or any undertaking, certificate or document
signed by it or supplied under the Loan by any person is shown
to be inaccurate, to the extent that such inaccuracy has a
material impact on the position of such Company,

5)   if the BANK OF FRANCE ("BANQUE DE FRANCE") ceases to
recognise such Company's signature,

6)   if such company is dissolved, subject to a voluntary
winding-up, or ceases to trade or to make payments,

7)   in the event of administration or judicial liquidation, or,
generally, any collective compromise proceedings relating to the
liabilities of such Company.

B\   The Bank reserves the right to declare the acceleration of
all the sums due from all the Borrowing Companies (except for
RHONE-POULENC S.A.) as regards principal, interest, default
interest, fees, costs and expenses, and no other drawing may be
made by any Borrowing Company (other than RHONE-POULENC S.A.) in
the following circumstances:

<PAGE>
<PAGE>

1)   failure to make payment within fifteen days following
receipt of a request for payment sent by the Bank to RHONE-
POULENC RORER INC as guarantor, of the sums not settled by any
one of RHONE-POULENC RORER S.A., RHONE-POULENC RORER LTD and
RHONE-POULENC RORER GmbH,

2)   if payment is not made by RHONE-POULENC RORER INC of any
sum due under the Loan on its due date, and such default is not
made good within fifteen days after receipt of a notice by the
Bank to such company by registered letter,

3)   if payment is not made by RHONE-POULENC RORER INC on their
due dates of sums due to any party under other borrowings, and
such default in payment has caused the acceleration of such
borrowings. Acceleration shall not be declared if the debt is
validly disputed or if the sums involved are of a nominal amount
of less than USD 10m or its equivalent.

4)   If RHONE-POULENC RORER INC does not comply with any of its
other obligations undertaken under the Loan or if a written
warranty made by such company or any undertaking, certificate or
document signed by it or supplied under the Loan by any person
is shown to be inaccurate, to the extent that such inaccuracy
has a material impact on the position of RHONE-POULENC RORER
INC,

5)   if the BANK OF FRANCE ("BANQUE DE FRANCE") ceases to
recognise RHONE-POULENC RORER INC's signature,

6)   if RHONE-POULENC RORER INC is dissolved, subject to a
voluntary winding-up, or ceases to trade or to make payments,

7)   in the event of administration or judicial liquidation, or,
generally, any collective compromise proceedings relating to the
liabilities of RHONE-POULENC RORER INC.

Any sums that shall have become payable under paragraphs A/ and
B/ shall bear interest at the rate applied during the current

<PAGE>
<PAGE>

drawing or renewal period. This rate shall be increased by 1% in
the event that the repayment of the sums does not take place
within eight days as from the due date; this provision shall not
constitute consent to late payment.

Any interest payable that is outstanding for a whole year shall
be capitalised in accordance with Article 1154 of the Civil
Code.

ARTICLE X - UNDERTAKINGS OF THE BORROWING COMPANIES

So long as any one of the Borrowing Companies shall be capable
of being a debtor hereunder, it shall:

- -  provide to the Bank as soon as possible and at the latest
within 90 days from the Ordinary General Meeting approving its
accounts, two copies of its annual balance sheets, profit and
loss accounts and documents attached thereto (consolidated
accounts so far as RHONE-POULENC S.A. and RHONE-POULENC RORER
INC are concerned),

- -  inform the Bank, as soon as possible, of any fact that may be
capable of affecting the size or value of its assets to a
material extent,

- -  keep the Bank informed of any changes to its bye-laws that may
be capable of affecting this loan by providing the new bye-laws
within one month from the resolution of shareholders approving
this change,

- -  immediately inform the Bank of changes to the powers of the
persons authorised to act on its behalf,

- -  undertake not to grant or allow to exist as security for any
future borrowings in an amount greater than 30 million US
dollars or as security for the guarantee of such a debt, any
mortgage, charge, pledge or any other right whatsoever over the
whole or any part of its assets or income, present or future,

<PAGE>
<PAGE>

unless the repayment or payment of all sums that may be due
under this Loan enjoys the same priority as such security, with
the exception of any security granted:

- - on an asset acquired after the date of signature of this
Agreement for the sole purpose of financing such acquisition and
to secure payment of sums not exceeding in principal the cost of
such acquisition,

- - to CREDIT NATIONAL, the EUROPEAN INVESTMENT BANK, the FONDS
INDUSTRIEL DE MODERNISATION, the FONDS DE DEVELOPPEMENT
ECONOMIQUE ET SOCIAL, or any other financial institution
controlled by the French State or the European Economic
Community and which, by law or its common practice, requires
such security.

Further, so long as any of the Borrowing Companies shall be
capable of being a debtor hereunder, RHONE-POULENC RORER INC
shall give prior notice to the Bank of any planned reduction in
its direct or indirect shareholding in the share capital of the
Borrowing Companies (other than RHONE-POULENC S.A.) which shall
result in reducing its shareholding such that any such company
shall become a subsidiary that is less than 50% owned.

ARTICLE XI - CHANGES OF CIRCUMSTANCE

The terms of this Agreement should be read as requiring full
payment to the Bank of all amounts falling due thereunder.

If interest or fees payable under the Loan become liable to any
duty, levy or tax whatsoever to which they are not currently
subject, the Borrower or any one of the Borrowing Companies
undertakes to pay the amount thereof, if evidence thereof is
given by the Bank, at the mere request of the latter, such that
the Bank shall bear no part thereof. Accordingly, the possible
lifting of or decrease in such new charges shall also be passed
on to the Borrowing Companies.

<PAGE>
<PAGE>

The occurrence of new circumstances of a monetary, financial,
banking or fiscal nature resulting from legal or regulatory
provisions or directives, recommendations or interpretations by
an official authority or a professional organisation that
results in the Bank incurring a new obligation leading to an
increased cost or the loss of a gain, linked directly or
indirectly to the transactions under this Agreement such as, for
example, the obligatory setting aside of reserves or making
deposits, a quantitative regulation of the loan, the
introduction or increase of liquidity ratios, own funds or other
matters relating to the whole of the assets or liabilities
(including off balance sheet liabilities), shall result in a
renegotiation of the terms.

In the event of disagreement at the end of a thirty day
negotiation period, commencing on the date of the despatch by
the Bank of a registered letter informing the Borrower of the
occurrence of an event bringing this clause into effect, each
party shall be entitled to repudiate the facility forthwith.

In such event, the Borrowing Companies shall bear the
supplementary cost and/or the loss of a gain referred to in the
above paragraph incurred by the Bank during such thirty day
period. RHONE-POULENC RORER INC shall secure the division
thereof between the Borrowing Companies.

ARTICLE XII - APPLICABLE LAW

The provisions of this confirmed Credit are governed by French
law, and the Courts of PARIS alone shall be competent to hear
and resolve any litigation, dispute or difficulty that may occur
between the parties in relation to the interpretation and
carrying out of the provisions of this Agreement.

<PAGE>
<PAGE>

ARTICLE XIII - MISCELLANEOUS

The Borrower shall bear all costs, levies and taxes, fees,
interest or other sums payable by reference to this Agreement or
resulting therefrom or consequent thereupon, and shall secure
the division thereof between the Borrowing Companies.

ARTICLE XIV - ELECTION OF RESIDENCE

Any notice concerning the confirmed Credit shall be sent:

- -  to the Borrower at the Registered Office of RHONE-POULENC
RORER S.A., 20 Avenue Raymond Aron, 92165 ANTONY CEDEX, where an
election in respect of residence is made,

- -  to the Bank at its LA DEFENSE Branch, where an election in
respect of residence is made.

                 Signed in PARIS, on 15th June 1993
                 in two original copies

  BANQUE NATIONALE DE PARIS        RHONE-POULENC RORER INC

/s/ Ervin        /s/ Alain              /s/ Patrick
    ROSENBERG        CHANTEREAU             LANGLOIS

    Ervin            Alain                  Patrick
    ROSENBERG        CHANTEREAU             LANGLOIS

<PAGE>
<PAGE>
                                                  Exhibit 10(b)

          FIRST SUPPLEMENTAL AGREEMENT TO THE AGREEMENT
                       OF 15TH JUNE, 1993

BETWEEN:

BANQUE NATIONALE DE PARIS, a "societe anonyme" with a share
capital of FRF 4,751,153,975, whose registered office is at 16
Boulevard des Italiens, 75009 Paris, registered with the Paris
Registry of Commerce and Companies under number B 662 042 449,

represented by:

- -  Mr. Jean-Daniel WURTZ, Manager of the Department
- -  Mr. Alain CHANTEREAU, Assistant Manager

(the "Bank", if not referred to by name)

                                  OF THE FIRST PART,

AND:

RHONE-POULENC RORER INC, a "societe anonyme" with a share
capital of USD, whose registered office is at 500 Arcola Road,
COLLEGEVILLE, PENNSYLVANIA 19426, UNITED STATES OF AMERICA,

represented by: Mr. Philippe MAITRE, Corporate Treasurer

(the "Borrower", if not referred to by name)

                                   OF THE SECOND PART,

<PAGE>
<PAGE>

On 15th June, 1993 RHONE-POULENC RORER INC and the Bank entered
into an Agreement (the "Agreement"), making available to RHONE-
POULENC RORER INC a loan (the "Loan"), in a maximum amount of
USD 200,000,000, under which drawings may be made in FRF, USD,
GBP and DEM. RHONE-POULENC RORER S.A., RHONE-POULENC RORER
LIMITED and RHONE-POULENC RORER GmbH may also make drawings
under the Loan, subject to certain conditions; RHONE-POULENC
RORER INC has guaranteed the indebtedness of such companies
under a guarantee signed on 15th June, 1993. RHONE-POULENC S.A.
may also make drawings thereunder.

At the request of RHONE-POULENC RORER INC, BNP agrees that the
amount of the loan should be increased, its duration be
extended, and to amend the rate of the margin contained in the
interest rates and the commitment fee.

At the request of RHONE-POULENC RORER INC, BNP also agrees that,
subject to certain conditions, the subsidiaries of RHONE-POULENC
RORER INC that are more than 50% owned by the company, other
than those already referred to in the Agreement, may make
drawings under the Loan.

WHEREAS IT IS AGREED AS FOLLOWS:

ARTICLE I

1.   The maximum amount of the loan defined in article I of the
Agreement is increased to a maximum amount of USD 250,000,000
(TWO HUNDRED AND FIFTY MILLION US DOLLARS) or its equivalent in
any other currency in which drawings may be made under the terms
of the Agreement.

<PAGE>
<PAGE>

2.   As a consequence, the sum referred to in article VI of the
Agreement is replaced by USD 250,000,000 (TWO HUNDRED AND FIFTY
MILLION US DOLLARS).

ARTICLE II

1.   The duration of the loan as defined in article II of the
Agreement is extended until 13.04.2000.

2.   As a consequence, the date referred to in article III of
the Agreement is replaced by the date 13.04.2000.

ARTICLE III

The margin of 0.25% referred in article VII - "CONDITIONS -
Interest" is decreased to 0.175%, provided that this reduction
shall come into effect at the end of each interest period
current at the date of entry into effect of this supplemental
agreement.

ARTICLE IV

The commitment fee of 0.20% referred to in article VII of the
Agreement is reduced to 0.125% per annum as from 15th June,
1995.

ARTICLE V

In the event that RHONE-POULENC S.A. reduces its direct or
indirect shareholding in the share capital of RHONE-POULENC
RORER INC to a level less than 51%, the terms set out in
articles III and IV of this supplemental agreement shall be
renegotiated at the request of BANQUE NATIONALE DE PARIS within
a maximum margin of 0.075%.

<PAGE>
<PAGE>

ARTICLE VI

Drawings under the Loan by RHONE-POULENC RORER S.A., RHONE-
POULENC RORER LTD and RHONE-POULENC RORER GmbH shall not exceed
a maximum principal amount of USD 200,000,000 (TWO HUNDRED
MILLION US DOLLARS) or its equivalent in one of the permitted
currencies under the Agreement, and shall be repaid by 15th
June, 1997, until the Guarantee of 15th June, 1993, attached as
schedule I to the Agreement, has been amended by a supplemental
agreement on the terms of schedule I hereto.

ARTICLE VII

Drawings may be made under the Loan by the subsidiaries of RHONE-
POULENC RORER INC that are more than 50% owned by that company,
in addition to those already set out in Article I of the
Agreement, subject to the following conditions:

- -  the prior written agreement of RHONE-POULENC RORER INC

- -  the prior written agreement of the Bank

- -  the prior receipt by the Bank of a letter from the relevant
subsidiary under which it enters into a direct undertaking to
the Bank, in the form of Schedule II to the Agreement. The terms
and conditions agreed with RHONE-POULENC RORER INC shall apply
to the relevant subsidiary.

- -  the prior grant of a guarantee by RHONE-POULENC RORER INC to
BANQUE NATIONALE DE PARIS in respect of the obligations of the
relevant subsidiary relating to the Loan, in the form of the
draft which shall be sent by the Bank to RHONE-POULENC RORER INC
at that time. This guarantee shall be duly authorised by the
Board of Directors of RHONE-POULENC RORER INC.

<PAGE>
<PAGE>

- -  the prior signature of a supplement to the Agreement
authorising the relevant subsidiary to make drawings under the
Loan.

ARTICLE VIII

On the basis of a drawing made on 12.04.1995 for a period of 3
months, the complete drawing of this loan in French francs would
show an effective global rate of 8.12% per annum, calculated on
the proportional basis.

ARTICLE IX

All the provisions of the Agreement that shall not have been
amended by this Supplemental Agreement shall remain in full
force and effect.

ARTICLE X

This Supplemental Agreement shall come into force once the
agreement of the subsidiaries of RHONE-POULENC RORER INC with
the Bank by way of acceptance of the commitments set out in
schedule II to the Agreement has been obtained.

                    Signed in PARIS, on 13th April 1995
                    in two original copies

        BANQUE NATIONALE DE PARIS            RHONE-POULENC RORER INC

/s/ Jean-Daniel WURTZ  /s/ Alain CHANTEREAU   /s/  Philippe Maitre

    Jean-Daniel WURTZ      Alain CHANTEREAU        Philippe Maitre

<PAGE>
<PAGE>

                                                  Exhibit 10(c)

ENGLISH TRANSLATION FOR INFORMATION ONLY


                    AMENDMENT NO. 2 TO THE AGREEMENT
                          OF 15TH JUNE, 1993


BETWEEN THE UNDERSIGNED:

BANQUE  NATIONALE DE PARIS, whose registered office  is  at  16,
boulevard  des  Italiens,  75009 Paris,  represented  by  Messrs
Philippe Arnold and Jean-Daniel Wurtz, duly authorised

hereinafter referred to as the "Bank"

                                     OF THE ONE PART
AND

RHONE-POULENC  RORER  INC.  whose  registered   office   is   at
Collegeville,   500   Arcola   Road,   Pennsylvania    (U.S.A.),
represented by Mr. Philippe Maitre

hereinafter referred to as the "Client"

                                     OF THE OTHER PART

WHEREAS:

By  an  agreement dated 15th June, 1993 the Bank granted to  the
Client  and  certain  of  its  subsidiaries  a  credit  facility
(hereinafter  referred to as the "Credit"). The  said  agreement
was amended by  Amendment no. 1 dated 13th April, 1995. The said
agreement  as  so  amended is hereinafter  referred  to  as  the
"Agreement".  At the Client's request, the Bank  has  agreed  to
amend  the  Agreement  anew  in accordance  with  the  following
provisions. Expressions defined in the Agreement have  the  same
meaning  as  in  this  amendment  (hereinafter  referred  to  as
"Amendment no. 2").

NOW IT IS HEREBY AGREED AS FOLLOWS:

CLAUSE 1        SPECIAL PERIOD

During  the period of seven months (hereinafter referred  to  as
the  "Special Period") which will commence upon delivery by  the
Client to the Bank (including by fax) of a certified copy of  an
extract of the minutes of a meeting of the Board of Directors of
the  Client ratifying the Amendment no. 2, such copy extract  to
be  delivered  to  the  Bank in any event not  later  than  11th
September, 1995, the following provisions shall be deemed to  be
contained  in  the  Agreement,  any  contrary  provision   being
inapplicable until the expiry of the Special Period.

(A) BORROWER

    Only  Rhone-Poulenc Rorer Inc. shall be entitled to use  the
    Credit.

<PAGE>
<PAGE>

(B) AMOUNT OF THE CREDIT

    The  amount  of  the Credit referred to, in  particular,  in
    Clauses  I and VI of the Agreement, is increased during  the
    Special  Period  to 1,700,000,000 United States  dollars  or
    the  equivalent  of  such amount in Deutsche  Marks,  French
    Francs or Pounds Sterling.

(C) PURPOSE OF THE CREDIT

    The  exclusive purpose of the Credit shall be the  financing
    or  refinancing  in whole or in part of (i) the  acquisition
    price  of  a  group of companies whose dominant activity  is
    similar  or complementary to that of the Client and  all  or
    some  of  whose holding company's share capital  is  listed,
    (ii)   the  indebtedness  (including  the  preferred  shares
    currently issued by the Client) of the Client or any of  its
    subsidiaries,  (iii)  the  expenses  associated  with   such
    acquisition  and (iv) any procedures related to  buying  out
    minorities.

(D) TERMS

    The  financial  terms of the Credit shall  remain  unchanged
    except,  during the Special Period, firstly, in  respect  of
    the  amount by reference to which they are to be taxed  and,
    secondly, in the following respects:-

        (i)the  Bank will receive from the Client a flat fee  of
        USD  150,000  in  respect of the preparation  and  costs
        incurred  in respect of the Amendment no. 2, payable  on
        the first day of the Special Period;

        (ii)    the  commitment commission provided for  in  the
        Agreement shall be payable monthly in advance.

    By  way of illustration, by reason of the temporary increase
    in  the  amount of the credit and on the basis of a  maximum
    drawing on 4th August, 1995 in FRF for 3 months, the  global
    effective  rate  calculated  on the  proportional  basis  is
    6.33% per annum.

(E) DURATION OF DRAWINGS

    The  Credit may be used subject to 2 business days,  in  the
    case of FRF, (prior to 11 a.m.) and 3 business days, in  the
    case  of USD, DEM or GBP, notice (prior to 11 a.m.)  by  way
    of  drawings  or  renewals of drawings denominated  in  USD,
    FRF,  DEM  or GBP with a minimum duration of 7  days  and  a
    maximum  duration  equal  to the remainder  of  the  Special
    Period.  The drawing date means the date on which funds  are
    made available.

(F) INTEREST

    As  regards  any  drawing period which is  not  an  integral
    multiple  of  1  month, other than 7  day  USD  drawings  or

<PAGE>
<PAGE>

    renewals,  the applicable rate shall be the sum of  (i)  the
    Bank's  offered rate in Paris for the relevant duration  and
    currency,  on  the preceding business day, in  the  case  of
    FRF,  and  two business days prior thereto, in the  case  of
    foreign currencies and (ii) a margin of 0.175% per annum.

    In  the  case  of  7  day  USD  drawings  or  renewals,  the
    reference  rate  shall be determined on  the  basis  of  the
    average  of  the rates published by NatWest, Bank  of  Tokyo
    and  Barclays  for 1 week on Reuter LIBOR page  at  11  A.M.
    (London  time)  2 business days prior to the  drawing  date,
    plus a margin of 0.175% per annum.

(G) EVENTS OF DEFAULT AND UNDERTAKINGS

    Clause  IX  of  the  Agreement shall not  apply  during  the
    Special  Period.  In  addition, failure  by  the  Client  to
    comply  with its obligations under Clause X of the Agreement
    shall  not  be  the  subject  of  any  sanction,  claim   or
    procedure whatsoever by the Bank.

(H) CHANGE OF CIRCUMSTANCES

    In  the  event of any of the circumstances described in  the
    third  paragraph  of  Clause XI  of  the  Agreement  arising
    during  the Special Period, the Client shall be entitled  to
    require  the Credit to be maintained and the Bank shall  not
    be  entitled  to repudiate it, provided that all  costs  and
    expenses  suffered by the Bank as a result thereof shall  be
    borne by the Client.


CLAUSE 2        OTHER PROVISIONS OF THE AGREEMENT

The  provisions of the Agreement which are not modified  by  the
above provisions shall remain in full force and effect.


CLAUSE 3        EXPIRY OF THE SPECIAL PERIOD

With  effect from the expiry of the Special Period, the  initial
provisions  of  the Agreement shall again become  applicable  as
they subsisted prior to modification by Amendment no. 2.



CLAUSE 4        APPLICABLE LAW

Clause XII of the Agreement also applies to the Amendment no. 2.


                                 Made in Paris (France)

                                 on 7th August, 1995



/s/ P. Arnold   /s/  J.D. Wurtz       /s/   P. Maitre
_______________________________     _________________________

    P. Arnold        J.D. Wurtz             P. Maitre

Banque Nationale de Paris            Rhone-Poulenc Rorer Inc.

<PAGE>
<PAGE>
                                             Exhibit 10(d)









                      RHONE-POULENC
                        RORER INC.








                 LOAN FACILITY AGREEMENT

                 dated 7th August, 1995














                      SOCIETE GENERALE


                      SLAUGHTER AND MAY
                     112, AVENUE KLEBER
                         75116 PARIS
<PAGE>
<PAGE>

THIS AGREEMENT IS MADE THE 7TH DAY OF AUGUST 1995

BETWEEN

SOCIETE  GENERALE,  a societe anonyme with a  share  capital  of
FRF  2,498,779,170, whose registered office is at 29,  boulevard
Haussmann, 75009 Paris, represented by Mr. Gerard GICQUEL

(hereinafter referred to as the "Bank")

                                         OF THE ONE PART

AND

RHONE-POULENC  RORER INC., a company with  a  share  capital  of
USD  429 million whose registered office is at Collegeville, 500
Arcola Road, Pennsylvania, United States of America, represented
by Mr. Philippe Maitre, Corporate Treasurer,

(hereinafter referred to as the "Client")

                                         OF THE OTHER PART

NOW IT IS HEREBY AGREED AS FOLLOWS:

CLAUSE 1 -  DEFINITIONS

The  following  definitions shall have the following  respective
meanings, unless the context other requires:-

"Available  Amount"  means,  on any  date,  the  amount  of  the
Facility less the aggregate amount of the Drawings outstanding.

"Business Day" means a whole day not being a Saturday  on  which
the interbank market is open or banks are open (i) in Paris,  in
the  case of French Franc Drawings and (ii) in London, Paris and
the  principal financial centre of the currency of the  Drawing,
in the case of any other Drawing.

"DEM" means Deutsche Marks.

"Drawing"  means a Drawing made under the Facility  or,  as  the
case may be, the amount thereof for the time being outstanding.

"Facility"  means  the  unconditional,  irrevocable,   confirmed
revolving facility made available by the Bank to the Client  the
maximum amount whereof is stated in Clause 3.

"FRF" means French Francs.

"GBP" means Pounds Sterling.

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"Reference  Banks"  means  (i) in the case  of  DEM,  Bayerische
Landesbank, Commerzbank, Deutsche Bank and Dresdner  Bank,  (ii)
in  the  case  of  FRF, Caisse Centrale des Banques  Populaires,
Caisse  des Depots et Consignations, Caisse Nationale du  Credit
Agricole and Credit Commercial de France, (iii) in the  case  of
GBP,  Barclays  Bank,  Lloyds Bank, Midland  Bank  and  National
Westminster  Bank and (iv) in the case of USD,  Chase  Manhattan
Bank, Chemical Bank, Citibank and J.P. Morgan.

"TMP" means the average rate recorded in day to day transactions
between  banks on the French inter-bank market and  weighted  by
volume,  as  published  by the Banque de  France  and  currently
available on Telerate page 3205.

"USD" means United States Dollars.

CLAUSE 2 - PURPOSE

The object of the Facility shall be the financing or refinancing
in  whole or in part of (i) the acquisition price of a group  of
companies whose dominant activity is similar or complementary to
that  of  the Client and all or some of whose holding  company's
share  capital is listed, (ii) the indebtedness (including share
capital  which may be repurchased or redeemed) of the Client  or
any of its subsidiaries, (iii) the expenses associated with such
acquisition  and  (iv)  any procedures  related  to  buying  out
minorities.

CLAUSE 3 - AMOUNT AND DURATION OF THE FACILITY

The   Bank   hereby  grants  to  the  Client  an  unconditional,
irrevocable,  confirmed revolving loan facility in  the  maximum
amount  of 1,100,000,000 United States Dollars or its equivalent
in Deutsche Marks, French Francs and Pounds Sterling.

Drawings  under the Facility may be made during  the  period  of
seven  months  (hereinafter referred  to  as  the  "Availability
Period")  commencing on the day following the date  of  delivery
(which  shall not be made later than 60 days after the  date  of
this Agreement) to the Bank of a certified copy of an extract of
the  minutes of the Board of Directors deciding on the principle
of  the  acquisition referred to in Clause 2 and  ratifying  the
signature of this Agreement by Mr. Philippe Maitre.

CLAUSE 4 - DRAWINGS

4.1 -    NOTICE OF DRAWING

     Each  Drawing shall be made on a Business Day. Any  request
     for  a Drawing must be notified to the Bank not later  than
     10  a.m.  (Paris  time) on the Business Day  prior  to  the
     proposed Drawing Date, in the case of FRF Drawings,  and  2
     Business  Days  in  the case of any  other  Drawings.   Any
     request  for renewals shall be subject to the same  notice.
     In  the  case of large Drawings, the Client shall,  to  the
     extent  possible,  inform the Bank  as  early  as  possible
     prior thereto.

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     Notification of a request for a Drawing shall be  given  by
     telephone  and shall be confirmed by fax by the  Client  in
     the form set out in the Schedule and any such fax shall  be
     as   effective  between  the  parties  as  if  it  were  an
     original.

     Subject  to Clauses 5.3.1 and 5.3.4, the notice of  Drawing
     duly  signed  by authorised persons shall irrevocably  bind
     the  Client  which  shall  make the  Drawing  on  the  date
     stipulated in the notice of Drawing.

4.2 -    DURATION AND AMOUNT OF EACH DRAWING

     Drawings  shall  not  exceed the Available  Amount  at  any
     given  time  and  may only be made for a  period  of  seven
     days,  one  month,  three months or  six  months,  and  all
     amounts due in respect thereof shall be paid or repaid  not
     later than the last day of the Availability Period.

     The  amount of each Drawing shall not be less than USD  TEN
     MILLION,  or  the equivalent thereof for Drawings  in  DEM,
     FRF  or  GBP.   The Client shall, to the extent  reasonably
     possible,  use  its best endeavours to keep the  number  of
     Drawings outstanding at any time to a minimum.

     Each  Drawing  shall  be repaid on  the  last  day  of  the
     relevant  Drawing period or, if such day is not a  Business
     Day, on the following Business Day.

4.3 -    ACCOUNTING AND AVAILABILITY OF FUNDS

     In  order  to keep accounting records of the implementation
     of  this  Facility the Bank shall open in the name  of  the
     Client  a  special  account which shall be  a  non-running,
     simple accounting mechanism which shall not have the  legal
     effects of a running account ("compte courant").

     The amount of each Drawing shall be entered by the Bank  as
     a credit in the current account of the Client.

     The   transactions   resulting  from   the   Drawings   and
     repayments  of  the  credit  shall  be  excluded  from  all
     running accounts which the Client has or may have with  the
     Bank.

     The  Client  acknowledges that the making and repayment  of
     borrowings hereunder shall be adequately evidenced  in  the
     accounts of the Bank.

CLAUSE 5 - FEES - INTEREST

5.1 -    MANAGEMENT FEE

     The  Client shall pay to the Bank, on the date of signature
     of   this   Agreement,  a  management  fee  in  an   amount
     (excluding tax) of 150,000 US Dollars.

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5.2 -    FACILITY FEE

     A  Facility  fee  calculated on the  total  amount  of  the
     Facility, being U.S.D. 1,100,000,000 subject to Clause  8.2
     (whether  or  not any Drawing is made) on  a  360-day  year
     basis  shall be paid to the Bank quarterly in advance,  and
     the  first  payment shall be made on the date of  signature
     of this Agreement.

     The  Facility fee shall be at a rate of 1/8 of 1% per annum
     until the expiry of this Agreement.

5.3 -    INTEREST

5.3.1    - Calculation of interest on Drawings in French Francs

     Subject  to  the provisions of Clause 5.3.7, the  reference
     rate  applicable  to Drawings of 1, 3 or 6  months  is  the
     corresponding PIBOR as defined in Clause 5.3.2.

     As  regards seven day Drawings, the reference rate shall be
     determined  by the Bank as being the average  (rounded  up,
     if  necessary, to the nearest 1/16 of 1% per annum) of  the
     rates   at   which  deposits  are  offered  in  the   Paris
     inter-bank  market by the relevant Reference Banks  on  the
     Business  Day preceding the proposed Drawing Date at  about
     11.00  a.m.  (Paris time) for a duration and in  an  amount
     equal  to  those  of the relevant Drawing. The  Bank  shall
     forthwith  inform  the  Client  of  such  determination  by
     telephone, whereupon the Client shall be entitled,  if  the
     rate  so determined is not acceptable to it, to cancel  the
     Drawing or select a duration of 1, 3 or 6 months therefor.

     Interest  in respect of any FRF Drawing shall be calculated
     at  the  aggregate of the reference rate and  a  margin  of
     0.175%  per annum on the basis of the exact number of  days
     in the Drawing period divided by 360.

     Interest  shall  be payable without deduction  for  impost,
     taxes and/or withholding at source.

     Interest  shall be payable on the last day of the  relevant
     Drawing  period or, if such day is not a Business  Day,  on
     the following Business Day.

5.3.2    - Definition of PIBOR

     PIBOR,  in respect of any French Franc denominated  Drawing
     means  the  annual  rate published by  TELERATE  (currently
     page  20041)  under the aegis of the Association  Francaise
     des  Banques  ("AFB") at about 11.30 a.m. (Paris  time)  on
     the  Business  Day preceding the proposed Drawing  date  or
     the  date  of renewal thereof, as being the rate  at  which
     French  Franc  deposits are offered on the Paris  Interbank
     Market  for the period of such Drawing or renewal,  as  the
     case may be.

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5.3.3    - Non-publication of PIBOR

     If  PIBOR,  as calculated and published by the AFB,  ceases
     to  be  published for any reason whatsoever the Bank  shall
     forthwith  notify  the  Client  by  any  method   and   the
     following provisions shall apply:-

         -  if  a  reference rate replacing PIBOR  is  published
         under  the  aegis  of  the  AFB,  such  rate  shall  be
         immediately   applicable  to  any  new   Drawings   and
         renewals thereof;

         -  otherwise,  the Bank and the Client shall  negotiate
         in  order to agree a new reference rate for 1, 3  or  6
         months Drawings.

     In  the  event of failure to agree and for so  long  as  no
     mechanism for the determination of a reference rate for  1,
     3  or  6  month  Drawings shall not  have  been  officially
     established,  Drawings  may only be  made  for  periods  of
     seven  days and interest shall accrue thereon in accordance
     with the second paragraph of Clause 5.3.1.

5.3.4.    - Calculation of interest on Drawings in USD,  DEM  or
GBP

     Drawings in USD, DEM or GBP shall have a duration of  seven
     days, 1, 3 or 6 months.

     The  Client may request two Business Days prior to the  end
     of  each Drawing period the conversion in whole or in  part
     of  one  or  more Drawings into a currency  of  its  choice
     (being  USD,  DEM,  FRF  or  GBP)  without  exceeding   the
     Available  Amount, subject to such conversion not resulting
     in  the  Facility  amount being exceeded (by  virtue  of  a
     change  of  parity between the currencies used  and  United
     States  Dollars) by 5% or more of the total Facility amount
     Provided  that  the Client shall eliminate such  excess  by
     adjusting  the amount of subsequent Drawings to the  extent
     necessary.

     Subject  to  the  preceding paragraph,  repayment  of  each
     Drawing  shall  be  made  in the  currency  in  which  such
     Drawing is denominated.

     Subject  to Clause 5.3.8, the reference rate applicable  to
     Drawings  in USD, DEM or GBP for a duration of 1,  3  or  6
     months shall be LIBOR as defined in Clause 5.3.5.

     As  regards seven day Drawings, the relevant reference rate
     shall  be  determined  by the Bank  as  being  the  average
     (rounded  up, if necessary, to the nearest 1/16 of  1%  per
     annum)  of the rates at which deposits are offered  in  the
     London  inter-bank market by the relevant  Reference  Banks
     two  Business Days preceding the proposed Drawing  date  at
     about  11.00 a.m. (London time) for a duration  and  in  an
     amount  equal  to those of the relevant Drawing.  The  Bank
     shall forthwith inform the Client of such determination  by
     telephone, whereupon the Client shall be entitled,  if  the
     rate  so determined is not acceptable to it, to cancel  the

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     Drawing or select a duration of 1, 3 or 6 months therefor.

     Interest  in respect of any USD, DEM or GBP Drawings  shall
     be  calculated  at the aggregate of the relevant  reference
     rate  and  a margin of 0.175% per annum in accordance  with
     euromarket practice on a 365/360 basis not later  than  the
     first  day of each period selected, except that it will  be
     calculated on a 365/365 basis for GBP.

     Interest  shall  be payable without deduction  for  impost,
     taxes and/or withholding at source.

     Interest  shall be payable on the last day of the  relevant
     Drawing  period or, if such day is not a Business  Day,  on
     the following Business Day.

     In  the  event that, at the date for repayment of a Drawing
     in  USD,  DEM  or GBP, the relevant currency shall  not  be
     available on the London interbank market, the Bank and  the
     Client  shall consult with a view to reaching agreement  on
     a  replacement  currency for the payment of  principal  and
     interest  in  respect  of such Drawing  and,  failing  such
     agreement  within  two  Business Days,  FRF  shall  be  the
     replacement currency.

5.3.5    - Definition of LIBOR

     LIBOR  (London Interbank Offered Rate), in respect  of  any
     USD,  DEM or GBP denominated Drawing, means the annual rate
     published  by  TELERATE (currently  page  3750)  under  the
     aegis  of  the British Bankers Association at  about  11.00
     a.m.  (London time) two Business Days prior to the proposed
     Drawing date or date of renewal thereof, as being the  rate
     at  which deposits in the relevant currency are offered  on
     the  London Interbank Market for the period of such Drawing
     or renewal, as the case may be.

5.3.6    - Unavailability of LIBOR

     In  the  event  that the Bank shall be unable to  determine
     LIBOR,   the   Bank  shall  promptly  notify  the   Client,
     whereupon   the   Client  and  the  Bank   shall   commence
     negotiations  with a view to finding a mutually  acceptable
     solution.  The Bank shall be under no obligation to  pursue
     such  negotiation after the expiry of a period of  30  days
     after   the  date  of  such  notice.  In  the  absence   of
     agreement,   the  applicable  reference   rate   shall   be
     determined  by the Bank as being the average  (rounded  up,
     if  necessary, to the nearest 1/16 of 1% per annum) of  the
     rates   at  which  deposits  are  offered  in  the   London
     inter-bank market by the Reference Banks two Business  Days
     preceding  the  proposed Drawing Date at about  11.00  a.m.
     (London  time)  for a duration and in an  amount  equal  to
     those of the relevant Drawing.

5.3.7     -  1,  3 and 6 month French Franc Drawings  substitute
rate

     In  the event that, on the Business Day prior to a proposed
     Drawing  date  or date of renewal thereof, the  Bank  shall

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     determine,   as  a  result  of  consulting   the   relevant
     Reference Banks in Paris, that the arithmetic mean  of  the
     rates  at  which FRF deposits are offered by  them  in  the
     Paris  inter-bank market for a duration and  in  an  amount
     equivalent to those of the relevant Drawing is higher  than
     the  PIBOR  which would otherwise apply to such Drawing  by
     more  than  1/16% per annum, the applicable reference  rate
     shall  be that determined by the Bank as being the  average
     (rounded  up, if necessary, to the nearest 1/16 of  1%  per
     annum)  of  the rates at which FRF deposits are offered  in
     the  Paris  inter-bank market by such  Reference  Banks  on
     such  Business  Day at about 11.30 a.m.  (Paris  time)  for
     such duration and amount.

5.3.8    - 1, 3 or 6 month DEM or GBP Drawings substitute rate

     In  the event that, on the second Business Day prior to the
     date on which funds are to be made available in respect  of
     a  Drawing  or a renewal thereof, the Bank shall determine,
     as  a result of consulting the relevant Reference Banks  in
     London,  that  the arithmetic mean of the  rates  at  which
     deposits  in the relevant currency are offered by  them  in
     the  London  inter-bank market for a  duration  and  in  an
     amount  equivalent  to  those of the  relevant  Drawing  is
     higher  than the LIBOR which would otherwise apply to  such
     Drawing  by  more  than  1/16% per  annum,  the  applicable
     reference  rate  shall be that determined by  the  Bank  as
     being  the  average  (rounded  up,  if  necessary,  to  the
     nearest  1/16  of  1%  per annum) of  the  rates  at  which
     deposits  in  the  relevant currency  are  offered  in  the
     London  inter-bank market by such reference banks  on  such
     Business  Day  at about 11.30 a.m. (London time)  for  such
     duration and amount.

5.3.9    - Reference Banks

     Whenever  a  reference rate shall be set on  the  basis  of
     Reference  Banks'  quotations, the Bank shall  notify  such
     quotations  to  the  Client.  The Bank's  determination  of
     reference  rates on such basis, shall, in  the  absence  of
     manifest error, be conclusive.

     In  the  event that no or only one Reference Bank  provides
     any  quotation  prior  to  the making  or  renewal  of  any
     Drawing, the reference rate for such Drawing shall  be  the
     annual  rate which the Bank shall certify to the Client  as
     representing  the  cost  of  funding  such  Drawings   from
     external  sources,  such certificate to be  accompanied  by
     relevant evidence of such cost.

5.4 -    PLACE OF PAYMENT

     All  payments to be made under this Agreement shall be made
     by transfer to the account of the Bank:-

         (i)    in  the  case  of  DEM,  with  Societe  Generale
         Frankfurt   -  SOGE  DE  FF,  Mainzer  Landstrasse   36
         Postfach  101935, D6000 Frankfurt Am Main  1  (Germany)
         under   reference  Rhone-Poulenc  Rorer/Franklin,   Mme

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         Francoise Graviche-Loiseau - Eurocredits;

         (ii)   in the case of FRF, with Societe Generale  Paris
         -   SOGE   FR   PP,   under   reference   Rhone-Poulenc
         Rorer/Franklin  (Code  Guichet  699-3),  Mme  Francoise
         Graviche-Loiseau - Eurocredits;

         (iii)  in the case of GBP, with Societe Generale London
         -  SGE  GB  2L, Exchange House Primrose Street,  London
         EC2A    2HT    (United   Kingdom),   under    reference
         Rhone-Poulenc     Rorer/Franklin,     Mme     Francoise
         Graviche-Loiseau - Eurocredits;

         (iv)   in  the  case of USD, with Societe Generale  New
         York  -  SOGE  US 33, currently at 1221 avenue  of  the
         Americas,  New  York  N.Y. 10020 (United  States),  no.
         0152595  under  reference Rhone-Poulenc Rorer/Franklin,
         Mme Francoise Graviche-Loiseau - Eurocredits.

     The  Client  irrevocably authorises the Bank to deduct  the
     amount  required  for payment of all sums  due  under  this
     Agreement  from  its  current account at  SOCIETE  GENERALE
     OPERA, 6, rue Auber, 75009 Paris.

CLAUSE 6 - EFFECTIVE GLOBAL RATE

For  the  purposes of sections L. 313-3 et seq.  of  the  French
Consumers  Code  ("Code  de  la  Consommation")  and  the  order
("decret") 85-944 of 4th September, 1985 and assuming a  maximum
borrowing  denominated in USD for the term of the  Facility  and
otherwise on the financial terms set out in this Agreement,  the
Bank  hereby notifies the Client, by way of example, that  LIBOR
for  one  month  being  5.875%, the  effective  global  rate  is
therefore 6.29% per annum.

The  effective  global  rate applicable for  each  Drawing  will
depend  on  the  manner in which Drawings are  made  under  this
Agreement.

CLAUSE 7 - CHANGES IN CIRCUMSTANCES

The  terms for remunerating the Bank in respect of the  Facility
have  been  fixed on the basis of the regulations applicable  on
the  date  of  signature  of  this Agreement  and  the  Client's
membership of the RHONE-POULENC Group.

If  RHONE-POULENC S.A.'s direct or indirect participation in the
capital  of RHONE-POULENC RORER INC. falls below 50%,  the  Bank
and  the  Client  shall  agree either on  a  prepayment  of  the
Facility  together with interest and all other amounts  relating
thereto  or  on increased terms, which in any event shall  be  a
maximum of PIBOR (for French Franc Drawings) or LIBOR (for  USD,
DEM  or GBP Drawings) plus 0.25% and a Facility fee of 0.25% per
annum.

If,  following  a  new  legislative or regulatory  provision  or
interpretation  by  a  competent authority,  such  provision  or

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authority  being  French, European, United  States  or  foreign,
whereby  the Bank is subject to any tax, monetary, financial  or
banking measure resulting in an additional cost relating to this
Agreement  (arising,  for example, from reserves  or  obligatory
deposits, share capital, liquidity or other ratios or  any  tax,
or  other  taxation,  except corporation  tax)  resulting  in  a
reduction of payment to the Bank or if such reduction of payment
results from a judicial decision, the following provisions shall
apply:-

- -    the  Bank  shall  notify the Client in writing,  indicating
     the estimated increase in costs under this Agreement or  of
     the  reduction of its payment in respect of this  Agreement
     and  the  required indemnity, enclosing documents providing
     evidence thereof,

- -    the  Client  and the Bank, on the initiative  of  the  Bank
     shall  consult as soon as practicable and negotiate  during
     a  maximum  period  of 30 days from the date  of  the  said
     notice  in  order  to reach a solution  which  permits  the
     resolution of any difficulties arising, in the same  spirit
     of cooperation as presided over this Agreement.

In  the  event  of  disagreement at the end  of  the  period  of
consultation, the Client shall have the option within a  maximum
period  of  seven business days following the last  day  of  the
period of 30 days either:-

- -    to  request  the Bank to continue the Facility, undertaking
     nevertheless  to  be wholly liable for the additional  cost
     incurred by the Bank from the day such cost is incurred  by
     the Bank; or

- -    to  terminate the Facility by prepayment of all sums due in
     principal,  interest and fees, increased  as  necessary  by
     all  fees  and all costs incurred by the Bank  relating  to
     such   prepayment  (including  and  upon  presentation   of
     evidence, the estimated cost of replacing the funds on  the
     date of prepayment).

CLAUSE 8 - CANCELLATION

8.1  AUTOMATIC CANCELLATION

     The  Facility  shall  expire 60  days  after  the  date  of
     signature  of  this Agreement in the event  of  the  Client
     failing  to deliver the certified copy extract referred  to
     in Clause 3 prior to the expiry of such 60 days.

8.2  VOLUNTARY CANCELLATION

     The Client may at any time cancel the Facility in whole  or
     in part, subject to prior written notice to the Bank.

     However,  such  cancellation shall only have  effect  seven
     calendar  days after receipt of such letter  by  the  Bank.
     Such  cancellation shall be definitive so that  the  amount
     of the Facility shall be reduced accordingly.

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     Consequently, the Facility fee shall cease  to  be  due  on
     the  cancelled portion of the Facility with effect from the
     expiry  of the quarterly period for the Facility fee during
     which the cancellation has taken effect.

CLAUSE 9 - PREPAYMENT

The  Client  may  not  prepay one or more  outstanding  Drawings
without the prior express consent of the Bank.

In  the event of such consent, such prepayment may be made  upon
the following conditions:-

- -    each  prepayment  shall be in respect of a  whole  Drawing.
     It may only be effected on a Business Day;

- -    the request for prepayment by the Client shall relate to  a
     minimum  of  USD 50,000,000 and shall reach the  Bank  with
     seven calendar days' prior notice;

- -    the  Client  shall  indemnify the Bank  for  all  potential
     losses  to  the Bank resulting from the difference  between
     the  interest rate applied to the relevant Drawing and  the
     rate  obtained by the Bank in replacing the  funds  on  the
     market  during  the  remaining period  until  the  date  of
     repayment of the Drawing.

CLAUSE 10 - DEFAULT INTEREST

All  sums  due  under this Agreement shall without prior  notice
bear interest at TMP, in the case of French Franc amounts, or at
the  relevant overnight London inter-bank offered  rate  in  the
case of USD, DEM or GBP amounts plus, in each case, 1% per annum
from their due date for payment until actual payment.

Such  provision shall not constitute a waiver of the  obligation
to pay on the relevant due date.

Interest  shall  be capitalised if it is due  for  one  year  in
accordance with the provisions of 1154 of the Civil Code.

CLAUSE 11 - TAXES AND EXPENSES

Payment of any sum due by the Client under this Agreement  shall
be  effected net of any tax retained at source or any present or
future withholding of whatever nature.

The  Client  shall  be  liable for all duly  evidenced  expenses
incurred  in good faith by the Bank in the preparation,  signing
and performance of this Agreement up to USD 30,000. In addition,
the Client shall be liable for all expenses and fees incurred by
the Bank in recovering sums due by the Client.

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CLAUSE 12 - WAIVERS

The  non-exercise  or late exercise by the  Bank  of  any  right
arising  out of this Agreement shall not constitute a waiver  of
that  right.  Any partial exercise of a right shall not preclude
any  further  exercise  of  rights which  have  not  been  fully
exercised.   The  rights  provided  in  this  Clause  shall   be
cumulative with any right provided by law.

CLAUSE 13 - DOMICILE

For  the performance of this Agreement, the Bank elects  as  its
domicile the place indicated in Clause 14 and, the Client elects
its registered office.

CLAUSE 14 - NOTICES

Any  notice to be given under this Agreement shall be  addressed
as follows:-

(i)  if to the Bank, to

     FOR CREDIT MATTERS:

     Societe Generale
     MARC/FIN/Acq
     Tour Societe Generale
     17 cours Valmy
     92987 Paris La Defense Cedex
     France

     For  the  attention  of Mr. Dominique  LEROY/Mlle  Isabelle
     LE BOULC'H

     Fax no.: (33.1) 42 13 79 13  Tel no.: (33.1) 42 13 75 98

     FOR OPERATIONAL AND ADMINISTRATIVE MATTERS:

     Societe Generale
     MARC/GEF/tit/eur
     Tour Societe Generale
     17 cours Valmy
     92987 Paris La Defense Cedex
     France

     For the attention of Mlle Laurence Gaertner

     Fax no.: (33.1) 42 13 69 67 Tel no.: (33.1) 42 13 77 71

(ii) if to the Client, to

     Rhone-Poulenc Rorer Inc.
     500 Arcola Road
     Collegeville
     Pennsylvania
     United States of America

<PAGE>
<PAGE>

     For the attention of the Corporate Treasurer
     or in his absence the Deputy Corporate Treasurer

     Fax no.: 610 454 8605  Tel no.: 610 454 3510

or,  in  either case, to such other address as may  be  notified
from time to time for that purpose by the relevant party.

CLAUSE 15 - GOVERNING LAW

This  Agreement shall be governed by French law and all disputes
not  resolved  by  common agreement shall be  submitted  to  the
non-exclusive jurisdiction of the Tribunal de Commerce of Paris.


                                   SIGNED IN PARIS,

                                   IN TWO ORIGINALS



/s/ Gerard Gicquel                     /s/ Philippe Maitre


SOCIETE GENERALE                       RHONE-POULENC RORER INC.

<PAGE>
<PAGE>
                                             Exhibit 10(e)










                      RHONE-POULENC
                        RORER INC.







                 LOAN FACILITY AGREEMENT

                  dated 7th August 1995






                        CREDIT LYONNAIS



                        SLAUGHTER AND MAY
                       112, AVENUE KLEBER
                           75116 PARIS

<PAGE>
<PAGE>

THIS AGREEMENT IS MADE THE 7TH DAY OF AUGUST 1995

BETWEEN

CREDIT  LYONNAIS, a French corporation with a stated capital  of
FRF  9,389,925,000, whose registered office is at  Lyon  (Rhone)
18, avenue de la Republique and whose principal office is at 19,
boulevard   des   Italiens,   75002  Paris,   registered   under
No.  B  954  509  741, Lyon Commercial Register  represented  by
Jean-Louis JOUBERT

(hereinafter referred to as the "Bank")

                                         OF THE ONE PART

AND

RHONE-POULENC  RORER INC., a company with  a  share  capital  of
USD  429 million whose registered office is at Collegeville, 500
Arcola Road, Pennsylvania, United States of America, represented
by Mr. Philippe Maitre, Corporate Treasurer,

(hereinafter referred to as the "Client")

                                         OF THE OTHER PART

NOW IT IS HEREBY AGREED AS FOLLOWS:

CLAUSE 1 -  DEFINITIONS

The  following  definitions shall have the following  respective
meanings, unless the context other requires:-

"Available  Amount"  means,  on any  date,  the  amount  of  the
Facility less the aggregate amount of the Drawings outstanding.

"Business Day" means a whole day not being a Saturday  on  which
the interbank market is open or banks are open (i) in Paris,  in
the  case of French Franc Drawings and (ii) in London and Paris,
in the case of any other Drawing.

"Drawing"  means a Drawing made under the Facility  or,  as  the
case may be, the amount thereof for the time being outstanding.

"Facility"  means  the  unconditional,  irrevocable,   confirmed
facility  made available by the Bank to the Client  the  maximum
amount whereof is stated in Clause 2.

"Reference  Banks"  means  (i) in the case  of  DEM,  Bayerische
Landesbank,  Caisse des Depots et Consignations and Commerzbank,
(ii)  in  the  case of FRF, Caisse des Depots et  Consignations,
Caisse  Nationale  du Credit Agricole and Credit  Commercial  de
France,  (iii)  in  the case of GBP, Barclays Bank,  Caisse  des

<PAGE>
<PAGE>

Depots  et  Consignations and Lloyds Bank and  (iv)  Caisse  des
Depots et Consignations, Chemical Bank and J.P. Morgan.

CLAUSE 2 - PURPOSE

The object of the Facility shall be the financing or refinancing
in  whole or in part of (i) the acquisition price of a group  of
companies whose dominant activity is similar or complementary to
that  of  the Client and all or some of whose holding  company's
share  capital is listed, (ii) the indebtedness (including share
capital  which may be repurchased or redeemed) of the Client  or
any of its subsidiaries, (iii) the expenses associated with such
acquisition  and  (iv)  any procedures  related  to  buying  out
minorities.

CLAUSE 3 - AMOUNT AND DURATION OF THE FACILITY

The   Bank   hereby  grants  to  the  Client  an  unconditional,
irrevocable,  confirmed loan facility in the maximum  amount  of
1,500,000,000  United  States  Dollars  or  its  equivalent   in
Deutsche Marks, French Francs and Pounds Sterling.

Drawings  under the Facility may be made during  the  period  of
seven  months  (hereinafter referred  to  as  the  "Availability
Period") commencing on the date of delivery (which shall not  be
made later than 60 days after the date of this Agreement) to the
Bank  of  a certified copy of an extract of the minutes  of  the
Board of Directors ratifying the signature of this Agreement.

CLAUSE 4 - DRAWINGS

4.1 -    NOTICE OF DRAWING

     Each  Drawing shall be made on a Business Day. Any  request
     for  a Drawing must be notified to the Bank not later  than
     10  a.m.  (Paris  time) on the Business Day  prior  to  the
     proposed Drawing Date, in the case of FRF Drawings,  and  2
     Business  Days  in  the case of any  other  Drawings.   Any
     request for renewals shall be subject to the same notice.

     Notification of a request for a Drawing shall be  given  by
     the  Client in the form set out in the Schedule and may  be
     sent  by  fax  which  shall  be as  effective  between  the
     parties  as  if  it were an original and the Client  hereby
     relieves the Bank of any liability which might result  from
     any  faulty,  improper or fraudulent use of such  means  of
     transmission other than by the Bank.

     Subject  to Clauses 5.3.1 and 5.3.4, the notice of  Drawing
     duly  signed  by authorised persons shall irrevocably  bind
     the  Client  which  shall  make the  Drawing  on  the  date
     stipulated in the notice of Drawing.

<PAGE>
<PAGE>

4.2 -    DURATION AND AMOUNT OF EACH DRAWING

     Drawings  not exceeding the Available Amount  may  be  made
     for  a period of eight days, one month, three months or six
     months,  and  all amounts due in respect thereof  shall  be
     paid  or  repaid  not  later  than  the  last  day  of  the
     Availability Period.

     The  amount  of  each Drawing shall not be  less  than  USD
     FIFTY  MILLION, or the equivalent thereof for  Drawings  in
     DEM, FRF or GBP.

     Each  Drawing  shall  be repaid on  the  last  day  of  the
     relevant  Drawing period or, if such day is not a  Business
     Day,  on  the  following Business Day except  that  if  the
     following Business Day falls in a new calendar month,  then
     on the preceding Business Day.

4.3 -    ACCOUNTING AND AVAILABILITY OF FUNDS

     In  order  to keep accounting records of the implementation
     of  this  Facility the Bank shall open in the name  of  the
     Client  a  special  account which shall be  a  non-running,
     simple accounting mechanism which shall not have the  legal
     effects of a running account.

     The amount of each Drawing shall be entered by the Bank  as
     a credit in the current account of the Client.

     The   transactions   resulting  from   the   Drawings   and
     repayments  of  the  credit  shall  be  excluded  from  all
     running accounts which the Client has or may have with  the
     Bank.

     The  Client  acknowledges that the making and repayment  of
     borrowings hereunder shall be adequately evidenced  in  the
     accounts of the Bank.

CLAUSE 5 - FEES - INTEREST

5.1 -    MANAGEMENT FEE

     The  Client shall pay to the Bank, on the date of signature
     of  this Agreement, a management fee in an amount excluding
     tax of 150,000 US Dollars.

5.2 -    COMMITMENT FEE

     A  commitment fee shall be paid to the Bank in arrear every
     90   days  after  the  date  of  this  Agreement   or,   if
     applicable, at the termination of the Availability  Period,
     and  calculated at a rate of 0.15% per annum on  the  daily
     Available  Amount  during the relevant 90  day  period  (or
     other such period, if applicable) on a 360-day year basis.

<PAGE>
<PAGE>

5.3 -    INTEREST

5.3.1    - Calculation of interest on Drawings in French Francs

     The interest reference rate applicable to Drawings of 1,  3
     or  6  months  is  the corresponding PIBOR  as  defined  in
     Clause 5.3.2.

     As  regards eight day Drawings, the relevant reference rate
     shall  be  determined  by the Bank  as  being  the  average
     (rounded  up, if necessary, to the nearest 1/16 of  1%  per
     annum)  of the rates at which deposits are offered  in  the
     Paris  inter-bank  market by prime banks  to  the  relevant
     Reference Banks on the Business Day preceding the  proposed
     Drawing  Date  at  about  11.00 a.m.  (Paris  time)  for  a
     duration  and  in an amount equal to those of the  relevant
     Drawing.  The  Bank shall forthwith inform  the  Client  of
     such  determination  by  telephone,  whereupon  the  Client
     shall  be  entitled,  if  the rate  so  determined  is  not
     acceptable  to  it,  to  cancel the  Drawing  or  select  a
     different duration therefor.

     Interest  in respect of any FRF Drawing shall be calculated
     at  the  aggregate  of the relevant reference  rate  and  a
     margin  of  0.325%  per annum, on the basis  of  the  exact
     number of days in the Drawing period divided by 360.

     Interest  shall  be paid on the last day  of  the  relevant
     Drawing  period or, if such day is not a Business  Day,  on
     the  following  Business Day, except that if the  following
     Business  Day falls in a new calendar month,  then  on  the
     preceding Business Day.

5.3.2    - Definition of PIBOR

     PIBOR,  in respect of any French Franc denominated  Drawing
     means  the  annual  rate published by  TELERATE  (currently
     page  20041)  under the aegis of the Association  Francaise
     des  Banques  ("AFB") at about 11.30 a.m. (Paris  time)  on
     the  Business Day preceding the proposed Drawing or renewal
     date, as being the rate at which French Franc deposits  are
     offered  on  the Paris Interbank Market for the  period  of
     such Drawing or renewal, as the case may be.

5.3.3    - Non-publication of PIBOR

     If  PIBOR,  as calculated and published by the AFB,  ceases
     to  be  published for any reason whatsoever the Bank  shall
     forthwith  notify  the  Client  by  any  method   and   the
     following provisions shall apply:-

         -  if  a  reference rate replacing PIBOR  is  published
         under  the  aegis  of  the  AFB,  such  rate  shall  be
         immediately   applicable  to  any  new   Drawings   and
         renewals thereof;

<PAGE>
<PAGE>

         -  otherwise,  the Bank and the Client shall  negotiate
         in  order to agree a new reference rate for 1, 3  or  6
         months Drawings.

     In  the  event of failure to agree and for so  long  as  no
     mechanism for the determination of a reference rate for  1,
     3  or  6  month  Drawings shall not  have  been  officially
     established,  Drawings may only be made for  periods  of  8
     days  and interest shall acrrue thereon in accordance  with
     the second paragraph of Clause 5.3.1.

5.3.4.    - Calculation of interest on Drawings in USD,  DEM  or
GBP

     Drawings  in  USD, DEM or GBP shall have a  duration  of  8
     days, 1, 3 or 6 months.

     The  Client may request two Business Days prior to the  end
     of  each  Drawing  period the conversion  of  one  or  more
     Drawings, in whole or, if in part, then in minimum  amounts
     of  USD  50  million or approximate equivalents thereof  in
     another authorised currency, into a currency of its  choice
     without  exceeding the Available Amount,  subject  to  such
     conversion  not  resulting  in the  Facility  amount  being
     exceeded  by  virtue  of  a change of  parity  between  the
     currencies used and United States Dollars.

     Subject  to  the  preceding paragraph,  repayment  of  each
     Drawing  shall  be  made  in the  currency  in  which  such
     Drawing is denominated.

     The  reference rate applicable to Drawings in USD,  DEM  or
     GBP  for  a duration of 1, 3 or 6 months shall be LIBOR  as
     defined  in  Clause 5.3.5.  Provided that the Client  shall
     pay   to  the  Bank,  in  the  case  of  any  GBP  Drawing,
     additional  interest  equal to the difference  between  the
     LIBOR  applied to such Drawing and the actual rate at which
     and  the  LIBOR  which would have applied if  it  had  been
     determined on the Drawing date.

     As  regards eight day Drawings, the relevant reference rate
     shall  be  determined  by the Bank  as  being  the  average
     (rounded  up, if necessary, to the nearest 1/16 of  1%  per
     annum)  of the rates at which deposits are offered  in  the
     London  inter-bank market by prime banks  to  the  relevant
     Reference  Banks two Business Days preceding  the  proposed
     Drawing  date  at  about 11.00 a.m.  (London  time)  for  a
     duration  and  in an amount equal to those of the  relevant
     Drawing.  The  Bank shall forthwith inform  the  Client  of
     such  determination  by  telephone,  whereupon  the  Client
     shall  be  entitled,  if  the rate  so  determined  is  not
     acceptable  to  it,  to  cancel the  Drawing  or  select  a
     different duration therefor.

     Interest  in  respect of any USD, DEM or GBP Drawing  shall
     be  calculated  at the aggregate of the relevant  reference
     rate  and a margin of 0.325% per annum, in accordance  with
     euromarket  practice on a 365/360 basis at the commencement
     of  each period selected, except that it will be calculated
     on a 365/365 basis for GBP.

<PAGE>
<PAGE>

     Interest   shall   be   payable   without   any   deduction
     whatsoever,  including for impost, taxes and/or withholding
     at source.

     Interest  shall  be paid on the last day  of  the  relevant
     Drawing  period or, if such day is not a Business  Day,  on
     the  following  Business Day except that if  the  following
     Business  Day falls in a new calendar month,  then  on  the
     preceding Business Day.

     In  the  event that, at the date for repayment of a Drawing
     in  USD,  DEM  or GBP, the relevant currency shall  not  be
     available on the interbank market, the Bank and the  Client
     shall  consult  with  a  view to reaching  agreement  on  a
     replacement  currency  for  the payment  of  principal  and
     interest  in  respect  of such Drawing  and,  failing  such
     agreement, FRF shall be the replacement currency.

5.3.5    - Definition of LIBOR

     LIBOR  (London Interbank Offered Rate), in respect  of  any
     USD,  DEM or GBP denominated Drawing, means the annual rate
     published  by  TELERATE (currently  page  3750)  under  the
     aegis  of  the British Bankers Association at  about  11.00
     a.m.  (London time) two Business Days prior to the proposed
     Drawing  or  renewal  date, as  being  the  rate  at  which
     deposits  in  the  relevant currency  are  offered  on  the
     London  Interbank Market for the period of such Drawing  or
     renewal, as the case may be.

5.3.6    - Unavailability of LIBOR

     In  the  event  that the Bank shall be unable to  determine
     LIBOR,   the   Bank  shall  promptly  notify  the   Client,
     whereupon   the   Client  and  the  Bank   shall   commence
     negotiations  with a view to finding a mutually  acceptable
     solution.  The Bank shall be under no obligation to  pursue
     such  negotiation after the expiry of a period of  30  days
     after   the  date  of  such  notice.  In  the  absence   of
     agreement,   the  applicable  reference   rate   shall   be
     determined  by the Bank as being the average  (rounded  up,
     if  necessary, to the nearest 1/16 of 1% per annum) of  the
     rates   at  which  deposits  are  offered  in  the   London
     inter-bank market by prime banks to the relevant  Reference
     Banks  two  Business  Days preceding the  proposed  Drawing
     Date  at about 11.00 a.m. (London time) for a duration  and
     in an amount equal to those of the relevant Drawing.

5.3.7    - Evidence

     Whenever a reference rate shall be determined on the  basis
     of  reference banks' quotations, notice of such  quotations
     shall,  upon  request by the Client, forthwith be  provided
     by the Bank to the Client.

<PAGE>
<PAGE>

5.4 -    PLACE OF PAYMENT

     All  payments to be made under this Agreement shall be made
     by  transfer to the account of Credit Lyonnais  -  DME,  La
     Defense  6, Tour Credit Lyonnais Cedex 10, 92081  Paris  La
     Defense.

CLAUSE 6 - EFFECTIVE GLOBAL RATE

For  the  purposes of sections L. 313-3 et seq.  of  the  French
Consumers  Code  ("Code  de  la  Consommation")  and  the  order
("decret") 85.944 of 4th September, 1985 and assuming a  maximum
borrowing for the term of the Facility by renewable Drawings  of
one month and the financial terms set out in this Agreement, the
Bank hereby notifies the Client, by way of example, that:-

- -  PIBOR  for  one month on 3rd August, 1995, being 6.1250%  per
   annum, the contractual interest rate is 6.45% per annum,

- -  the rate for a period of one month is accordingly 0.53750%,

- -  the effective global rate is therefore 6.45017% per annum.

The  effective  global  rate applicable for  each  Drawing  will
depend  on  the  manner in which Drawings are  made  under  this
Agreement.

CLAUSE 7 - CHANGES IN CIRCUMSTANCES

The  terms for remunerating the Bank in respect of the  Facility
have  been  fixed on the basis of the regulations applicable  on
the date of signature of this Agreement.

If,  following  a  new  legislative or regulatory  provision  or
interpretation  by  a  competent authority,  such  provision  or
authority being French, European or foreign, whereby the Bank is
subject  to  any  tax, monetary, financial  or  banking  measure
resulting  in  an  additional cost relating  to  this  Agreement
(arising,  for  example, from reserves or  obligatory  deposits,
share  capital, liquidity or other ratios or any tax,  or  other
taxation,  except corporation tax) resulting in a  reduction  of
any  amounts received or to be received by the Bank or  if  such
reduction of any amounts received or to be received by the  Bank
results from a judicial decision, the following provisions shall
apply:-

- -  the  Bank shall notify the Client in writing, indicating  the
   estimated  increase in costs under this Agreement or  of  the
   reduction  of  its payment in respect of this  Agreement  and
   the   required   indemnity,  enclosing  documents   providing
   evidence thereof,

- -  the  Client and the Bank, on the initiative of the Bank shall
   consult  as  soon  as  practicable  and  negotiate  during  a
   maximum  period of 30 days from the date of the  said  notice
   in  order to reach a solution which permits the resolution of

<PAGE>
<PAGE>

   any  difficulties arising, in the same spirit of  cooperation
   as presided over this Agreement.

In  the  event  of  disagreement at the end  of  the  period  of
consultation, the Client shall have the option within a  maximum
period  of 7 business days following the last day of the  period
of 30 days either:-

- -  to  request  the  Bank to continue the Facility,  undertaking
   nevertheless  to  be  wholly liable for the  additional  cost
   incurred  by  the Bank from the day such cost is incurred  by
   the Bank; or

- -  to  terminate the Facility by prepayment of all sums  due  in
   principal, interest and fees, increased as necessary  by  all
   fees  and  all  costs incurred by the Bank relating  to  such
   prepayment (including and upon presentation of evidence,  the
   estimated  cost  of  replacing  the  funds  on  the  date  of
   prepayment).

CLAUSE 8 - CANCELLATION

8.1  AUTOMATIC CANCELLATION

   The  Facility  shall  expire  60  days  after  the  date   of
   signature  of  this  Agreement in the  event  of  the  Client
   failing to deliver the certified copy extract referred to  in
   Clause  3 prior to the expiry of such 60 days, whereupon  the
   Client  shall pay the commitment fee to the Bank  as  if  the
   Facility had been in force for 90 days.

8.2  VOLUNTARY CANCELLATION

   The  Client may at any time cancel the Facility in  whole  or
   in  part,  subject to 15 days' prior written  notice  to  the
   Bank.

   Such  cancellation shall be definitive so that the amount  of
   the  Facility shall be reduced accordingly and the commitment
   fee  shall  cease to be due on the cancelled portion  of  the
   Facility  with  effect from the expiry of such notice  period
   Provided Always that in respect of the first 90 days of  this
   Agreement,  the  fee  shall be due as  if  the  Facility  had
   remained fully in force for such 90 days.

CLAUSE 9 - PREPAYMENT

The  Client  may  not  prepay one or more  outstanding  Drawings
without the prior express consent of the Bank.

In  the event of such consent, such prepayment may be made  upon
the following conditions:-

- -  each  prepayment shall be in respect of a whole Drawing.   It
   may only be effected on a Business Day;

- -  the  request  for  prepayment by the Client shall  reach  the
   Bank with 7 calendar days' notice;

<PAGE>
<PAGE>

- -  the  Client shall indemnify the Bank for all potential losses
   to  the  Bank  resulting  from  the  difference  between  the
   interest  rate applied to the relevant Drawing and  the  rate
   obtained  by  the Bank in replacing the funds on  the  market
   during  the  remaining period until the date of repayment  of
   the Drawing.

CLAUSE 10 - DEFAULT INTEREST

All  sums  due  under this Agreement shall without prior  notice
bear  interest at TMP or at the overnight rate for the  relevant
currency plus 1% per annum from their due date for payment until
actual payment.

Such  provision shall not constitute a waiver of the  obligation
to pay on the relevant due date.

Interest  shall  be capitalised if it is due  for  one  year  in
accordance with the provisions of 1154 of the Civil Code.

CLAUSE 11 - TAXES AND EXPENSES

Payment of any sum due by the Client under this Agreement  shall
be  effected net of any tax retained at source or any present or
future withholding of whatever nature.

The Client shall be liable for all expenses and fees incurred by
the  Bank  in  recovering  sums due by  the  Client  under  this
Agreement.

CLAUSE 12 - WAIVERS

The  non-exercise  or late exercise by the  Bank  of  any  right
arising  out of this Agreement shall not constitute a waiver  of
that  right.  Any partial exercise of a right shall not preclude
any  further  exercise  of  rights which  have  not  been  fully
exercised.   The  rights  provided  in  this  Clause  shall   be
cumulative with any right provided by law.

CLAUSE 13 - DOMICILE

For the performance of this Agreement and subsequent agreements,
the  Bank  elects as its domicile the place indicated above  for
payments and, the Client elects its registered office.

<PAGE>
<PAGE>

CLAUSE 14 - GOVERNING LAW

This  Agreement shall be governed by French law and all disputes
not  resolved  by  common agreement shall be  submitted  to  the
non-exclusive jurisdiction of the Tribunal de Commerce of Paris.


                                 SIGNED IN PARIS,
                                 IN TWO ORIGINALS


/s/ Jean-Louis Joubert               /s/  Philippe Maitre

    Jean-Louis Joubert                    Phillipe Maitre


  CREDIT LYONNAIS                  RHONE-POULENC RORER INC.


                                                      EXHIBIT 11
                                                                
               RHONE-POULENC RORER INC. AND SUBSIDIARIES
                Computation of Earnings Per Common Share
    (Unaudited-dollars and shares in millions except per share data)

                                                Three Months Ended
                                                  September 30,
                                                -------------------
                                                           Restated
                                                 1995        1994
                                               --------    --------
Net income per common share as reported:                    
Net income before preferred dividend           $  112.1    $  114.5
Less: Dividend on preferred stock                  (4.8)       (4.9)
                                               --------    --------
Net income available to common shareholders    $  107.3       109.6
                                               ======== 
Pro forma adjustments for interest and                     
   preferred dividends, net of tax effects                     (2.4)
                                                           --------
Net income available to common shareholders,               
   pro forma                                               $  107.2
                                                           ========
Average shares outstanding                        134.2       134.8
                                               ========    ========
Net income available to common shareholders  
   per share                                   $    .80  
                                               ========
Net income available to common shareholders                
   per share, pro forma                                    $   0.80
                                                           ========
                                                           
Net income per common share assuming full                  
   dilution:
Net income before preferred dividend           $  112.1    $  114.5
Less: Dividend on preferred stock                  (4.8)       (4.9)
                                               --------    --------
Net income available to common shareholders    $  107.3       109.6
                                               ========
Pro forma adjustments for interest and                     
   preferred dividends, net of tax effects                     (2.4)
                                                           --------
Net income available to common shareholders,               
   pro forma                                               $  107.2
                                                           ========
Average shares outstanding                         134.2      134.8
Shares contingently issuable for stock plan          0.7        0.4
                                               ---------   --------
Average shares outstanding, assuming full    
   dilution                                        134.9      135.2
                                               =========   ========
Net income available to common shareholders                
   per share, assuming full dilution           $    0.80  
                                               =========            
Net income available to common shareholders                
   per share, pro forma, assuming full dilution            $   0.79
                                                           ========

This calculation is submitted in accordance with the regulations
of the Securities and Exchange Commission although not required
by APB Opinion No. 15 because it results in dilution of less
than 3%.

<PAGE>
<PAGE>
                                                      EXHIBIT 11
                                                                
               RHONE-POULENC RORER INC. AND SUBSIDIARIES
                Computation of Earnings Per Common Share
    (Unaudited-dollars and shares in millions except per share data)



                                                Nine Months Ended
                                                  September 30,
                                               --------------------
                                                           Restated
                                                 1995        1994
                                               --------    --------
Net income per common share as reported:                    
Net income before preferred dividend           $  298.7    $  193.9
Less: Dividend on preferred stock                 (16.2)      (13.8)
                                               --------    --------
Net income available to common shareholders       282.5       180.1
Pro forma adjustments for interest and                     
preferred dividends, net of tax effects            (1.6)       (6.6)
                                               --------    --------
Net income available to common shareholders, 
   pro forma                                   $  280.9    $  173.5
                                               ========    ========            
Average shares outstanding                        134.2       135.6
                                               ========    ========

Net income available to common shareholders 
   per share, pro forma                        $   2.09    $   1.28
                                               ========    ========   
Net income per common share assuming full                  
   dilution:
Net income before preferred dividend           $  298.7    $  193.9
Less: Dividend on preferred stock                 (16.2)      (13.8)
                                               --------    --------
Net income available to common shareholders       282.5       180.1
Pro forma adjustments for interest and                     
   preferred dividends, net of tax effects         (1.6)       (6.6)
                                               --------    --------
Net income available to common shareholders, 
   pro forma                                   $  280.9    $  173.5
                                               ========    ========      
Average shares outstanding                        134.2       135.6
Shares contingently issuable for stock plan         0.7         0.5
                                               --------    --------
Average shares outstanding, assuming full     
   dilution                                       134.9       136.1
                                               ========    ========
Net income available to common shareholders                
   per share, pro forma, assuming full        
   dilution                                    $   2.08    $   1.27
                                               ========    ========

This calculation is submitted in accordance with the regulations
of the Securities and Exchange Commission although not required
by APB Opinion No. 15 because it results in dilution of less
than 3%.









                                                              EXHIBIT 15


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC  20549

                            RE:    Rhone-Poulenc Rorer Inc.
                                   Quarterly Report on Form 10-Q


We are aware that our report dated October 20, 1995, on our
review of interim financial information of Rhone-Poulenc Rorer
Inc. ("the Company"), for the period ended September 30, 1995,
and included in the Company's quarterly report on Form 10-Q for
the quarter then ended is incorporated by reference in the
registration statements of the Company on Form S-3 (Registration
No. 33-58229, Registration No. 33-62052, Registration No. 33-
36558, Registration No. 33-30795, Registration No. 33-23754,
Registration No. 33-15671, Registration No. 33-43941,
Registration No. 33-53378 and Registration No. 33-55694) and on
Form S-8 (Registration No. 33-58998, Registration No. 33-24537,
Registration No. 2-61635, Registration No. 2-78374 and
Registration No. 33-21902).  Pursuant to Rule 436(c) under the
Securities Act of 1933, this report should not be considered a
part of the registration statements prepared or certified by us
within the meaning of Sections 7 and 11 of that Act.




                              /s/  COOPERS & LYBRAND L.L.P.
                             ----------------------------------
                                   COOPERS & LYBRAND L.L.P.






Philadelphia, Pennsylvania
November 14, 1995


<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM CONDENSED
CONSOLIDATED BALANCE SHEET AND THE RELATED CONDENSED CONSOLIDATED STATEMENT OF
INCOME FOR THE NINE-MONTH PERIOD ENDING SEPTEMBER 30, 1995 AND IS QUALIFIED IN
ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000,000
       
<S>                                        <C>
<PERIOD-TYPE>                                    9-MOS
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<RECEIVABLES>                                      860
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<INVENTORY>                                        713
<CURRENT-ASSETS>                                  2188
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<DEPRECIATION>                                    1257
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<COMMON>                                           139
                                0
                                        175
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<TOTAL-LIABILITY-AND-EQUITY>                      5093
<SALES>                                           3552
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<CGS>                                             1252
<TOTAL-COSTS>                                     3067
<OTHER-EXPENSES>                                    16
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<INTEREST-EXPENSE>                                  41
<INCOME-PRETAX>                                    428
<INCOME-TAX>                                       129
<INCOME-CONTINUING>                                299
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                       299
<EPS-PRIMARY>                                     2.09
<EPS-DILUTED>                                     2.08
        

</TABLE>


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