DREYFUS MONEY MARKET INSTRUMENTS INC
24F-2NT, 1995-02-24
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                        DREYFUS MONEY MARKET INSTRUMENTS, INC.
                                 200 PARK AVENUE
                               NEW YORK, NY  10166

                                                   February 24, 1995

Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, NW
Washington, DC  20549


    24f-2 Notice - DREYFUS MONEY MARKET INSTRUMENTS, INC.
    Registration Statement No. 2-52718 - CIK #0000030160

Gentlemen:

    On October 30, 1978, Post-Effective Amendment Nos. 14 and 15 to the
Registration Statement of Dreyfus Money Market Instruments, Inc. was declared
effective by the SEC, which represented the Fund's election to register an
indefinite number of shares of the Money Market Series.  On May 1, 1979, Post-
Effective Amendment No. 17 to the Registration Statement of Dreyfus Money
Market Instruments, Inc. was declared effective by the SEC which represented
the Fund's election to register an indefinite number of shares of the
Government Securities Series.  This Notice, filed pursuant to Rule 24f-2, is
for the fiscal year ended December 31, 1994.

     The following information is furnished:

     GOVERNMENT SECURITIES SERIES

     (a) Shares registered under Securities Act
         of 1933 other than pursuant to Rule 24f(2)
         which remained unsold on January 1, 1994:             868,017,685

     (b) Shares registered during fiscal year
         other than pursuant to Section 24(f):

         Post-Effective Amendment No. 46 effective 7/11/94     149,082,379
                                                             -------------

         Total of (a) and (b)                                1,017,100,064
                                                             =============

                                                  SHARES        DOLLAR AMOUNT

     (c) Total number of shares sold during
         fiscal year ended 12/31/94 subject
         to registration under Rule 24f-2:  1,082,467,060   $1,082,467,060

     (d) Less shares redeemed during
         fiscal year ended 12/31/94:        1,149,487,078   $1,149,487,078
                                           --------------   ----------------

    Net Sales During Year [(c) - (d)]:     (   67,020,018) ($   67,020,018)
                                           ===============  ================

    Less shares registered other
    than pursuant to Section 24(f)          1,017,100,064    1,017,100,064
                                           ---------------  ----------------


    Unsold balance of registered shares    (1,084,120,082) ($1,084,120,082)
                                           ================ ================

                                    -2-

     MONEY MARKET SERIES

     (a) Shares registered under Securities Act
         of 1933 other than pursuant to Rule 24f(2)
         which remained unsold on January 1, 1994:           3,017,220,485

     (b) Shares registered during fiscal year
         other than pursuant to Section 24(f):

         Post-Effective Amendment No. 46 effective 7/11/94      40,224,481
                                                               -------------

         Total of (a) and (b)                                3,057,444,966
                                                               =============

                                                  SHARES        DOLLAR AMOUNT

     (c) Total number of shares sold during
         fiscal year ended 12/31/94 subject
         to registration under Rule 24f-2:    363,712,784   $  363,712,784

     (d) Less shares redeemed during
         fiscal year ended 12/31/94:          405,184,351      405,184,351
                                            ---------------  ----------------

    Net Sales During Year [(c) - (d)]:     (   41,471,567) ($   41,471,567)
                                            ===============  ================

    Less shares registered other
    than pursuant to Section 24(f)          3,057,444,966    3,057,444,966
                                            ---------------  ----------------


    Unsold balance of registered shares    (3,098,916,533) ($3,098,916,533)
                                            ===============  ================


                            CALCULATION OF FEE

    Government Securities Series and Money Market Series - Since the shares
redeemed exceed the shares sold, no registration fee is required.  An opinion
of counsel is enclosed.



                                                   Very truly yours,

                                                   /s/ John J. Pyburn

                                                   John J. Pyburn,
                                                   Assistant Treasurer

JJP:jb

cc:  Mr. J. deMichaelis, SEC
     Ms. R. McLaughlin, E&Y
     Mr. S. Rosenberg, BONY


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