DREYFUS MONEY MARKET INSTRUMENTS INC
N-30D, 2000-02-22
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Dreyfus

Money Market

Instruments, Inc.

ANNUAL REPORT December 31, 1999

(reg.tm)





The  views  expressed herein are current to the date of this report. These views
and  the  composition  of the fund's portfolio are subject to change at any time
based on market and other conditions.

   * Not FDIC-Insured  * Not Bank-Guaranteed  * May Lose Value

Year 2000 Issues (Unaudited)

The fund could be adversely affected if the computer systems used by Dreyfus and
the fund's other service providers do not properly process and calculate
date-related information from and after January 1, 2000. Dreyfus has taken steps
designed to avoid year 2000-related problems in its systems and to monitor the
readiness  of other service providers.  In addition, issuers of securities in
which the fund invests may be adversely affected by year 2000-related problems.
This could have an impact on the value of the fund's investments and its share
price.


                                 Contents

                                 THE FUND
- --------------------------------------------------

                             2   Letter from the President

                             3   Discussion of Fund Performance

                             6   Statements of Investments

                            10   Statement of Assets and Liabilities

                            11   Statement of Operations

                            12   Statement of Changes in Net Assets

                            13   Financial Highlights

                            15   Notes to Financial Statements

                            19   Report of Independent Auditors

                            20   Important Tax Information

                                 FOR MORE INFORMATION
- ---------------------------------------------------------------------------

                                 Back Cover

                                                                       The Fund

                                                           Dreyfus Money Market

                                                              Instruments, Inc.

LETTER FROM THE PRESIDENT

Dear Shareholder:

We  are  pleased  to  present  this  annual  report  for  Dreyfus  Money  Market
Instruments,  Inc.,  covering  the  12-month period from January 1, 1999 through
December  31,  1999. Inside, you'll find valuable information about how the fund
was  managed  during the reporting period, including a discussion with portfolio
manager Thomas S. Riordan.

When  the  reporting period began, investors were concerned that global economic
weakness  might  cause  a  slowdown in the U.S. economy. As it turned out, these
fears  were  unfounded.  In  fact,  it  became  apparent  early in the year that
international and domestic economies were growing faster than analysts expected,
giving   rise   to  concerns  that  long-dormant  inflationary  pressures  might
re-emerge. Consumers continued to spend heavily, unemployment levels reached new
lows  and  the  stock  market continued to climb. Because unsustainable economic
growth  may  trigger  unwanted inflationary pressures, the Federal Reserve Board
raised key short-term interest rates three times between June 30 and year-end in
an  attempt  to  forestall  an  acceleration  of inflation. In this environment,
yields on money market securities continued to rise.

We  appreciate  your  confidence over the past year, and we look forward to your
continued participation in Dreyfus Money Market Instruments, Inc.

Sincerely,


Stephen E. Canter

President and Chief Investment Officer

The Dreyfus Corporation

January 14, 2000




DISCUSSION OF FUND PERFORMANCE

Thomas S. Riordan, Portfolio Manager

How did Dreyfus Money Market Instruments, Inc.  perform during the period?

For  the  12-month  period ended December 31, 1999, the fund produced a yield of
4.36%  for  its  Money  Market  Series  and  4.23% for its Government Securities
Series.  Taking  into account the effect of compounding, the effective yield was
4.45%  for  its  Money  Market  Series  and  4.31% for its Government Securities
Series.(1)

What factors influenced the fund's performance?

As  1999  began  the  United  States  economy was marked by fears of an economic
slowdown, largely as a result of the Asian financial crisis. The Federal Reserve
Board,  in  an attempt to cushion the economy from negative overseas events, had
sharply  lowered short-term interest rates. Global markets remained unsettled as
1999  began,  but  the  general atmosphere of crisis lifted. As fears waned, the
focus  of monetary policymakers shifted back to the domestic economy, and as the
economy  showed  no  signs  of  slowing,  the  Fed  began  to voice concern over
inflationary pressures.

The  performance  of  the  U.S.  economy  in  the first quarter of 1999 was much
stronger  than  expected.  But  while the Gross Domestic Product (GDP) grew at a
rate of 4.3%, inflation remained benign. Despite a tight labor market, there was
no  evidence  of  advancing  wage pressure. Many economic analysts believed that
advances  in  technology  might  make it possible for the economy to grow faster
than  previously  thought  possible  without igniting inflation. Notwithstanding
fears  that imbalances might eventually derail the nine-year expansion, the U.S.
economy  continued  to  grow  as  the Fed held steady on rates through the first
quarter of the year.

                                                             The Fund


DISCUSSION OF FUND PERFORMANCE (CONTINUED)

A surprisingly large jump in the Consumer Price Index in May pushed policymakers
closer  to  a  rate  hike.  Although  the Fed did not immediately raise interest
rates, it did announce a significant shift, adopting a "bias" towards tightening
- --  that  is, raising short-term rates. With that shift in bias came a resulting
shift  in  market  psychology, as participants began to anticipate higher rates

That  highly  anticipated  move  came in June, when at its Open Market Committee
meeting,  the Fed raised short-term rates by 0.25 percentage points. At the same
time,  however,  it  announced  that it was shifting its bias back to neutral --
indicating  no intention of an immediate further rate increase. The market hoped
that this pre-emptive strike to head off the threat of inflation would signal an
end    to    Fed    tightening.

Such  hopes  would  be  short-lived as strong economic growth along with anxiety
over  rising wages and benefits renewed inflationary concern. At its August Open
Market  Committee  meeting,  the  Fed  raised  short-term  interest  rates by an
additional  0.25  percentage points, signaling its added resolve by also raising
the    discount    rate.

The  economy  continued to give mixed signals to the money market throughout the
third  quarter.  GDP growth accelerated back to a rapid 4.8%, but key indicators
of  employment costs, job creation and inflation were at lower levels than would
be  expected,  given such strong economic expansion. These mixed indications led
the Fed to hold off on further tightening until November, when continued fear of
inflationary  pressures  caused  it  to  increase  short-term  interest rates by
another 0.25 percentage points.

When the Fed took no action at its December meeting, many analysts considered it
to  be  an  attempt  to  quiet  markets  that were concerned about potential Y2K
disruption.  The  Fed also added significant reserves to the banking system over
year-end  to  quell  liquidity concerns, leading to temporary irregularities and
wide  fluctuations  in  short-term interest rates. Despite the temporary drop in
rates    over    year-end    due

to  the added reserves, many believe, now that Y2K issues have been successfully
navigated,  that  the  issue  of  managing sustainable growth should take center
stage    again.

What is the fund's current strategy?

In  response  to  a market environment marked by rising interest rates, the fund
took on a somewhat defensive strategy. We took two steps to position the fund in
the  current  market:  we  shortened  the  fund' s  average maturity and built a
liquidity cushion. Shorter maturities and a higher level of cash are designed to
enable the fund to take advantage of a possible further rise in interest rates.

January 14, 2000

(1)  EFFECTIVE YIELD IS BASED UPON DIVIDENDS DECLARED DAILY AND REINVESTED
MONTHLY. PAST PERFORMANCE IS NO GUARANTEE OF FUTURE RESULTS. YIELDS FLUCTUATE.
AN INVESTMENT IN THE FUND IS NOT INSURED OR GUARANTEED BY THE FDIC OR ANY OTHER
GOVERNMENT AGENCY. ALTHOUGH THE FUND SEEKS TO PRESERVE THE VALUE OF YOUR
INVESTMENT AT $1.00 PER SHARE, IT IS POSSIBLE TO LOSE MONEY BY INVESTING IN THE
FUND.

                                                             The Fund

STATEMENT OF INVESTMENTS

Money Market Series

December 31, 1999

 Principal

<TABLE>
<CAPTION>


NEGOTIABLE BANK CERTIFICATES OF DEPOSIT--18.5%                                               Amount ($)               Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

Branch Bank & Trust Co.

   <S>                                                                                        <C>                      <C>
   5.04%, 1/10/2000                                                                           4,500,000                4,499,968

Deutsche Bank AG (Yankee)

   5.70%, 4/10/2000                                                                           5,000,000  (a)           4,999,399

Societe Generale N.A. Inc. (Yankee)

   5.70%, 4/20/2000                                                                           5,000,000                4,999,249

Union Bank of California

   5.98%, 8/1/2000                                                                            4,000,000                4,000,000

TOTAL NEGOTIABLE BANK CERTIFICATES OF DEPOSIT

   (cost $18,498,616)                                                                                                 18,498,616
- ------------------------------------------------------------------------------------------------------------------------------------

COMMERCIAL PAPER--41.9%
- ------------------------------------------------------------------------------------------------------------------------------------

Atlantis One Funding Corp.

   5.92%, 2/22/2000                                                                           4,500,000                4,462,625

BCI Funding Corp.

   6.05%, 5/2/2000                                                                            4,000,000                3,920,429

Commonwealth Bank of Australia

   6.00%, 4/6/2000                                                                            4,500,000                4,429,440

DaimlerChrysler North America Holding Corp.

   6.10%, 2/29/2000                                                                           4,500,000                4,456,045

Donaldson, Lufkin & Jenrette Securities Corp.

   6.22%, 3/3/2000                                                                            4,000,000                3,957,806

General Electric Capital Corp.

   5.93% , 6/16/2000                                                                          4,000,000                3,893,677

Goldman Sachs Group Inc.

   6.07%, 2/29/2000                                                                           4,500,000                4,456,266

Lehman Brothers Holdings Inc.

   6.20%, 3/8/2000                                                                            4,500,000                4,449,665

Santander Finance (DE) Inc.

   5.94%, 3/22/2000                                                                           4,000,000                3,947,575

UBS Finance (DE) Inc.

   4.25%, 1/3/2000                                                                            4,000,000                3,999,056

TOTAL COMMERCIAL PAPER

   (cost $41,972,584)                                                                                                 41,972,584
- ------------------------------------------------------------------------------------------------------------------------------------

CORPORATE NOTES--20.9%
- ------------------------------------------------------------------------------------------------------------------------------------

Bear, Stearns & Co. Inc.

   6.52%, 2/22/2000                                                                           5,000,000  (a)           5,000,388

Finova Capital Corp.

   6.09%, 8/15/2000                                                                           2,500,000                2,499,192


                                                                                              Principal

CORPORATE NOTES (CONTINUED)                                                                  Amount ($)                 Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

GTE Corp.

   6.22%, 6/12/2000                                                                           5,000,000  (a)           4,998,567

Heller Financial Inc.

   5.90%, 8/7/2000                                                                            4,000,000  (a)           4,000,000

Paine Webber Group Inc.

   6.66%, 9/15/2000                                                                           4,500,000  (a)           4,500,000

TOTAL CORPORATE NOTES

   (cost $20,998,147)                                                                                                 20,998,147
- ------------------------------------------------------------------------------------------------------------------------------------

SHORT-TERM BANK NOTES--5.0%
- ------------------------------------------------------------------------------------------------------------------------------------

First Tennessee Bank

  5.68%, 4/19/2000

   (cost $4,999,415)                                                                          5,000,000  (a)           4,999,415
- ------------------------------------------------------------------------------------------------------------------------------------

TIME DEPOSITS--11.6%
- ------------------------------------------------------------------------------------------------------------------------------------

Bank One NA (Grand Cayman)

   4.50%, 1/3/2000                                                                            4,000,000                4,000,000

Chase Manhattan Bank NA (London)

   4.00%, 1/3/2000                                                                            4,000,000                4,000,000

Republic National Bank of New York (London)

   4.50%, 1/3/2000                                                                            3,647,000                3,647,000

TOTAL TIME DEPOSITS

   (cost $11,647,000)                                                                                                 11,647,000
- ------------------------------------------------------------------------------------------------------------------------------------

TOTAL INVESTMENTS

   (cost $98,115,762)                                                                             97.9%               98,115,762

CASH AND RECEIVABLES (NET)                                                                         2.1%                2,090,207

NET ASSETS                                                                                       100.0%              100,205,969

(A)  VARIABLE INTEREST RATE--SUBJECT TO PERIODIC CHANGE.

SEE NOTES TO FINANCIAL STATEMENTS.
</TABLE>


                                                             The Fund

STATEMENT OF INVESTMENTS

Government Securities Series

December 31, 1999


<TABLE>
<CAPTION>


                                                                          Annualized
                                                                            Yield on
                                                                             Date of              Principal
U.S. TREASURY BILLS--31.6%                                               Purchase (%)            Amount ($)         Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

1/13/2000

   <S>                                                                           <C>             <C>              <C>
   (cost $114,791,083)                                                           5.47            115,000,000      114,791,083
- ------------------------------------------------------------------------------------------------------------------------------------

U.S. TREASURY NOTES--23.5%
- ------------------------------------------------------------------------------------------------------------------------------------

5.875%, 2/15/2000                                                                4.69             28,000,000       28,035,240

5.50%, 3/31/2000                                                                 4.66             25,000,000       25,037,360

5.50%, 5/31/2000                                                                 4.88             25,000,000       25,040,463

5.875%, 6/30/2000                                                                5.23              7,000,000        7,017,309

TOTAL U.S. TREASURY NOTES

  (cost $85,130,372)                                                                                               85,130,372
- ------------------------------------------------------------------------------------------------------------------------------------

REPURCHASE AGREEMENTS--44.6%
- ------------------------------------------------------------------------------------------------------------------------------------

Barclays Capital Inc.

   dated 12/31/1999, due 1/3/2000 in the amount of
   $4,921,615 (fully collateralized by $4,975,000
   U.S. Treasury Notes, 5.75%, due 11/15/2000,
   value $4,999,293)                                                             1.50             4,921,000         4,921,000

Bear, Stearns & Co. Inc.

   dated 12/31/1999, due 1/3/2000 in the amount of
   $31,006,458 (fully collateralized by $31,580,000
   U.S. Treasury Strips, due 2/15/2000,
   value $31,377,888)                                                            2.50            31,000,000        31,000,000

Donaldson, Lufkin & Jenrette Securities Corp. Inc.

   dated 12/31/1999, due 1/3/2000, in the amount of
   $33,005,500 (fully collateralized by $33,373,000
   U.S. Treasury Notes 5.625%, due 11/30/2000,
   value $33,412,714)                                                            2.00            33,000,000        33,000,000

Morgan (J.P.) & Co. Inc.

   dated 12/31/1999, due 1/3/2000 in the amount of
   $27,005,938 (fully collateralized by $27,066,000
   U.S. Treasury Notes, 5.50%, due 2/29/2000,
   value $27,539,505)                                                            2.64            27,000,000        27,000,000

Morgan Stanley Dean Witter & Co.

   dated 12/31/1999, due 1/3/2000 in the amount
   of $33,006,793 (fully collateralized by $33,455,000
   U.S. Treasury Notes, 5.625%, due 11/30/2000,
   value $33,478,419)                                                            2.47            33,000,000        33,000,000


                                                                           Annualized
                                                                            Yield on
                                                                             Date of              Principal
REPURCHASE AGREEMENTS (CONTINUED)                                        Purchase (%)            Amount ($)            Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

Warburg Dillion Read, Inc.

   dated 12/31/1999, due 1/3/2000, in the amount of
   $33,006,875 (fully collateralized by $35,395,000
   U.S. Treasury Bills, due 11/9/2000,
   value $33,660,645)                                                            2.50            33,000,000           33,000,000

TOTAL REPURCHASE AGREEMENTS

  (cost $161,921,000)                                                                                                161,921,000
- ------------------------------------------------------------------------------------------------------------------------------------

TOTAL INVESTMENTS

   (cost $361,842,455)                                                          99.7%                                361,842,455

CASH AND RECEIVABLES (NET)                                                        .3%                                  1,106,172

NET ASSETS                                                                     100.0%                                362,948,627

SEE NOTES TO FINANCIAL STATEMENTS.

</TABLE>


                                                             The Fund

STATEMENT OF ASSETS AND LIABILITIES

December 31, 1999

                                                            Money   Government
                                                           Market   Securities
                                                           Series       Series
- --------------------------------------------------------------------------------

ASSETS ($):

Investments in securities, See Statement of Investments
   (including repurchase agreements of $161,921,000 for
   the Government Securities Series)--Note 2(b)         98,115,762  361,842,455

Cash                                                     1,555,690      272,622

Interest receivable                                        667,647    1,102,793

Prepaid expenses                                             6,047       13,791

                                                       100,345,146  363,231,661
- --------------------------------------------------------------------------------

LIABILITIES ($):

Due to The Dreyfus Corporation and affiliates              87,697       196,921

Accrued expenses and other liabilities                     51,480        86,113

                                                          139,177       283,034
- --------------------------------------------------------------------------------

NET ASSETS ($)                                        100,205,969   362,948,627
- --------------------------------------------------------------------------------

COMPOSITION OF NET ASSETS ($):

Paid-in capital                                       100,236,117  363,036,071

Accumulated net realized gain (loss) on investments      (30,148)      (87,444)
- --------------------------------------------------------------------------------

NET ASSETS ($)                                        100,205,969   362,948,627

NET ASSET VALUE PER SHARE

                                                            Money   Government
                                                           Market   Securities
                                                           Series       Series
- --------------------------------------------------------------------------------

Net Assets ($)                                        100,205,969  362,948,627

Shares Outstanding                                    100,219,617  363,036,071

NET ASSET VALUE PER SHARE ($)                               1.00         1.00

SEE NOTES TO FINANCIAL STATEMENTS.


STATEMENT OF OPERATIONS

Year Ended December 31, 1999

                                                            Money   Government
                                                           Market   Securities
                                                           Series       Series
- --------------------------------------------------------------------------------

INVESTMENT INCOME ($):

INTEREST INCOME                                         5,433,942   20,813,488

EXPENSES--NOTE 2:

Management fee--Note 3(a)                                 512,901    2,083,776

Shareholder servicing costs--Note 3(b)                    328,510      842,132

Registration fees                                          43,440       30,007

Professional fees                                          32,821       14,551

Custodian fees                                             26,559       78,645

Directors' fees and expenses--Note 3(c)                    11,522       57,693

Prospectus and shareholders' reports                       11,183       22,836

Miscellaneous                                                  --        1,868

TOTAL EXPENSES                                            966,936    3,131,508

INVESTMENT INCOME--NET                                  4,467,006   17,681,980
- --------------------------------------------------------------------------------

NET REALIZED GAIN (LOSS) ON INVESTMENTS--NOTE 2(B) ($)    (1,333)     (87,197)

NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS    4,465,673   17,594,783

SEE NOTES TO FINANCIAL STATEMENTS.

                                                             The Fund

STATEMENT OF CHANGES IN NET ASSETS

<TABLE>
<CAPTION>


                                                        Money Market Series                         Government Securites Series
                                              --------------------------------------         ---------------------------------------

                                                Year Ended           Year Ended               Year Ended                Year Ended
                                              December 31,          December 31,             December 31,              December 31,
                                                      1999                  1998                     1999                      1998
- ------------------------------------------------------------------------------------------------------------------------------------

OPERATIONS ($):

<S>                                              <C>                   <C>                     <C>                       <C>
Investment income--net                           4,467,006             5,316,204               17,681,980                20,107,437

Net realized gain (loss)
   on investments                                  (1,333)               (6,557)                 (87,197)                    36,250

NET INCREASE (DECREASE)
   IN NET ASSETS
   RESULTING FROM OPERATIONS                     4,465,673              5,309,647              17,594,783                20,143,687
- ------------------------------------------------------------------------------------------------------------------------------------

DIVIDENDS TO
   SHAREHOLDERS FROM ($):

Investment income--net                         (4,467,006)            (5,316,204)             (17,681,980)             (20,107,437)

Net realized gain
   on investments                                     --                      --                      --                   (36,250)

TOTAL DIVIDENDS                                (4,467,006)            (5,316,204)             (17,681,980)             (20,143,687)
- ------------------------------------------------------------------------------------------------------------------------------------

CAPITAL STOCK TRANSACTIONS
   ($1.00 per share):

Net proceeds from
   shares sold                                 320,522,771            270,802,602            1,597,921,400            1,295,087,820

Dividends reinvested                             2,829,101              3,521,681               10,137,442               11,359,817

Cost of shares redeemed                       (333,779,964)          (282,449,373)          (1,672,681,750)          (1,259,780,722)

INCREASE (DECREASE) IN
   NET ASSETS
   FROM CAPITAL
   STOCK TRANSACTIONS                          (10,428,092)            (8,125,090)             (64,622,908)              46,666,915

TOTAL INCREASE (DECREASE)
   IN NET ASSETS                               (10,429,425)            (8,131,647)             (64,710,105)              46,666,915
- ------------------------------------------------------------------------------------------------------------------------------------

NET ASSETS ($):

Beginning of Period                            110,635,394            118,767,041              427,658,732              380,991,817

END OF PERIOD                                  100,205,969            110,635,394              362,948,627              427,658,732

SEE NOTES TO FINANCIAL STATEMENTS.
</TABLE>



FINANCIAL HIGHLIGHTS

Money Market Series

The  following tables describe the performance for the fiscal periods indicated.
Total return shows how much your investment in the fund would have increased (or
decreased)  during  each  period,  assuming you had reinvested all dividends and
distributions.  These  figures  have  been  derived  from  the  fund's financial
statements.

<TABLE>
<CAPTION>


                                                                                            Year Ended December 31,
                                                                 -------------------------------------------------------------------

                                                                 1999           1998          1997           1996          1995
- ------------------------------------------------------------------------------------------------------------------------------------

PER SHARE DATA ($):

<S>                                                              <C>            <C>           <C>            <C>           <C>
Net asset value, beginning of period                             1.00           1.00          1.00           1.00          1.00

Investment Operations:

Investment income--net                                            .044           .047          .047           .046          .053

Distributions:

Dividends from investment income--net                            (.044)         (.047)        (.047)         (.046)        (.053)

Net asset value, end of period                                   1.00           1.00          1.00           1.00          1.00
- ------------------------------------------------------------------------------------------------------------------------------------

TOTAL RETURN (%)                                                 4.45           4.76          4.76           4.73          5.46
- ------------------------------------------------------------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA (%):

Ratio of expenses to average net assets                           .94            .94          1.00            .93           .84

Ratio of net investment income
   to average net assets                                         4.35           4.66          4.66           4.63          5.33

Decrease reflected in above expense ratios
   due to undertakings by
   The Dreyfus Corporation                                         --            --            .01             --            --
- ------------------------------------------------------------------------------------------------------------------------------------

Net Assets, end of period ($ x 1,000)                         100,206        110,635        118,767       129,344        144,172

SEE NOTES TO FINANCIAL STATEMENTS.

</TABLE>


                                                             The Fund

FINANCIAL HIGHLIGHTS

Government Securities Series

<TABLE>
<CAPTION>


                                                                                          Year Ended December 31,
                                                                 -------------------------------------------------------------------

                                                                 1999           1998           1997          1996          1995
- ------------------------------------------------------------------------------------------------------------------------------------

PER SHARE DATA ($):

<S>                                                              <C>            <C>            <C>           <C>           <C>
Net asset value, beginning of period                             1.00           1.00           1.00          1.00          1.00

Investment Operations:

Investment income--net                                            .042           .047           .046          .045          .051

Distributions:

Dividends from investment income--net                            (.042)         (.047)         (.046)        (.045)        (.051)

Net asset value, end of period                                   1.00           1.00           1.00          1.00          1.00
- ------------------------------------------------------------------------------------------------------------------------------------

TOTAL RETURN (%)                                                 4.31           4.83           4.72          4.60          5.18
- ------------------------------------------------------------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA (%):

Ratio of expenses to average net assets                           .75            .69            .87           .90           .83

Ratio of net investment income
   to average net assets                                         4.24           4.71           4.62          4.50          5.07
- ------------------------------------------------------------------------------------------------------------------------------------

Net Assets, end of period ($ x 1,000)                         362,949        427,659        380,992       441,769       431,444

SEE NOTES TO FINANCIAL STATEMENTS.

</TABLE>



NOTES TO FINANCIAL STATEMENTS

NOTE 1--General:

Dreyfus  Money  Market  Instruments,  Inc.  (the "fund") is registered under the
Investment  Company  Act  of  1940,  as  amended  (the  "Act"), as a diversified
open-end  management investment company and operates as a series company issuing
two  classes  of  Common  Stock:  the  Money  Market  Series  and the Government
Securities  Series. The fund accounts separately for the assets, liabilities and
operations  of  each  series.  The  fund' s  investment  objective is to provide
investors  with  as  high  a  level  of current income as is consistent with the
preservation   of   capital  and  the  maintenance  of  liquidity.  The  Dreyfus
Corporation (the "Manager") serves as the fund's investment adviser. The Manager
is  a direct subsidiary of Mellon Bank, N.A., which is a wholly-owned subsidiary
of Mellon Financial Corporation.

Premier  Mutual  Fund  Services,  Inc.  is the distributor of the fund's shares,
which  are  sold to the public without a sales charge. The fund is authorized to
issue  5  billion  shares  of  $.001 par value Common Stock for the Money Market
Series  and 10 billion shares of $.001 par value Common Stock for the Government
Securities Series.

It  is  the  fund's policy to maintain a continuous net asset value per share of
$1.00  for  each  series;  the  fund  has  adopted certain investment, portfolio
valuation and dividend and distribution policies to enable it to do so. There is
no assurance, however, that the fund will be able to maintain a stable net asset
value per share of $1.00 for each series.

The  fund' s  financial  statements  are  prepared  in accordance with generally
accepted accounting principles which may require the use of management estimates
and assumptions. Actual results could differ from those estimates.

NOTE 2--Significant Accounting Policies:

(A) PORTFOLIO VALUATION: Investments in securities are valued at amortized cost,
which has been determined by the fund's Board of Directors to represent the fair
value    of    the    fund'   s    investments.

                                                             The Fund

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

(B)  SECURITIES  TRANSACTIONS AND INVESTMENT INCOME: Securities transactions are
recorded  on  a  trade  date  basis.  Realized  gain  and  loss  from securities
transactions  are  recorded  on  the  identified  cost basis. Interest income is
recognized  on the accrual basis. Cost of investments represents amortized cost.
Under the terms of the custody agreement, the Money Market Series and Government
Securities Series receives net earnings credits based on available cash balances
left on deposit.

The  fund  may  enter  into  repurchase  agreements with financial institutions,
deemed  to  be  creditworthy  by  the  fund' s  Manager, subject to the seller's
agreement  to repurchase and the fund's agreement to resell such securities at a
mutually   agreed   upon  price.  Securities  purchased  subject  to  repurchase
agreements are deposited with the fund's custodian and, pursuant to the terms of
the  repurchase  agreement,  must have an aggregate market value greater than or
equal  to  the repurchase price plus accrued interest at all times. If the value
of  the underlying securities falls below the value of the repurchase price plus
accrued  interest,  the  fund  will  require  the  seller  to deposit additional
collateral by the next business day. If the request for additional collateral is
not met, or the seller defaults on its repurchase obligation, the fund maintains
the  right  to  sell the underlying securities at market value and may claim any
resulting loss against the seller.

(C)  EXPENSES: Expenses directly attributable to each series are charged to that
series'  operations;  expenses which are applicable to both series are allocated
between them.

(D)  DIVIDENDS  TO  SHAREHOLDERS:  It is the policy of the fund, with respect to
both  series,  to  declare dividends from investment income-net on each business
day;  such dividends are paid monthly. Dividends from net realized capital gain,
with  respect  to both series, are normally declared and paid annually, but each
series  may  make  distributions  on  a  more  frequent basis to comply with the
distribution  requirements of the Internal Revenue Code of 1986, as amended (the
" Code" ). However,  to  the  extent  that a net realized capital gain of either
series can be reduced by a capital loss carryover of that series, such gain will
not be distributed.


(E) FEDERAL INCOME TAXES: It is the policy of each series to continue to qualify
as  a  regulated  investment  company,  if  such  qualification  is  in the best
interests  of  its  shareholders, by complying with the applicable provisions of
the  Code,  and to make distributions of taxable income sufficient to relieve it
from substantially all Federal income and excise taxes.

The  Money  Market  Series has an unused capital loss carryover of approximately
$30,000  available  for Federal income tax purposes to be applied against future
net securities profits, if any, realized subsequent to December 31, 1999. If not
applied,  $18,000  of  the  carryover  expires in fiscal 2004, $4,000 expires in
fiscal 2005, $7,000 expires in fiscal 2006 and $1,000 expires in fiscal 2007.

The  Government  Securities  Series  has  an  unused  capital  loss carryover of
approximately  $87,000  available  for federal income tax purposes to be applied
against  future  net securities profits, if any, realized subsequent to December
31, 1999. If not applied, the carryover expires in fiscal 2007.

At  December 31, 1999, the cost of investments of each series for Federal income
tax  purposes  was  substantially  the  same as the cost for financial reporting
purposes (see the Statements of Investments).

NOTE 3--Management Fee and Other Transactions With Affiliates:

(A)  Pursuant  to  a  management  agreement  ("Agreement") with the Manager, the
management  fee  for  each series is computed at the annual rate of .50 of 1% of
the value of the average daily net assets of each series and is payable monthly.
The Agreement provides that if in any full fiscal year the aggregate expenses of
either series, exclusive of taxes, brokerage commissions, interest on borrowings
and extraordinary expenses, exceed 1% of the value of such series' average daily
net  assets, the fund may deduct from payments to be made to the Manager, or the
Manager  will  bear  the  amount  of  such  excess. No expense reimbursement was
required for the period ended December 31, 1999 pursuant to the Agreement.

(B)  Under the Shareholder Services Plan, each series reimburses Dreyfus Service
Corporation,    a    wholly-owned    subsidiary    of    the     The    Fund

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

Manager,  an  amount  not  to exceed an annual rate of .25 of 1% of the value of
each  series'  average  daily  net  assets  for  certain  allocated  expenses of
providing   personal  services  and/or  maintaining  shareholder  accounts.  The
services   provided  may  include  personal  services  relating  to  shareholder
accounts,  such  as  answering  shareholder  inquiries  regarding  the  fund and
providing reports and other information, and services related to the maintenance
of  shareholder  accounts.  During the period ended December 31, 1999, the Money
Market  Series  and  the  Government Securities Series were charged $208,550 and
$513,607, respectively, pursuant to the Shareholder Services Plan.

The  fund  compensates  Dreyfus Transfer, Inc., a wholly-owned subsidiary of the
Manager,   under  a  transfer  agency  agreement  for  providing  personnel  and
facilities  to  perform transfer agency services for the fund. During the period
ended  December  31, 1999, the Money Market Series and the Government Securities
Series,  were  charged  $101,226  and  $258,863,  respectively,  pursuant to the
transfer agency agreement.

(C)  Each  director  who  is  not  an  "affiliated person" as defined in the Act
received from the fund an annual fee of $4,500 and an attendance fee of $500 per
meeting.  The  Chairman  of  the  Board  received  an  additional  25%  of  such
compensation.

Each non-affiliated director is a Board member of one or more funds comprising a
certain  group  of  funds  (" Fund Group") within the Dreyfus complex. Effective
January  1,  2000,  for  their  participation as a director in a Fund Group, the
directors  receive  an  annual  fee  of  $40,000  each,  $6,000 for each meeting
attended  in  person  and  $500  for  each  telephonic  meeting  in  which  they
participate.  These  fees  are  allocated among the funds in the Fund Group. The
Chairman of the Board receives an additional 25% of such compensation.


REPORT OF INDEPENDENT AUDITORS

Shareholders and Board of Directors

Dreyfus Money Market Instruments, Inc.

We  have audited the accompanying statement of assets and liabilities, including
the  statements  of  investments,  of  Dreyfus  Money  Market  Instruments, Inc.
(comprising, respectively, the Money Market Series and the Government Securities
Series) , as  of  December 31, 1999, and the related statement of operations for
the  year then ended, the statement of changes in net assets for each of the two
years  in  the period then ended, and financial highlights for each of the years
indicated  therein.  These financial statements and financial highlights are the
responsibility  of  the  Fund' s management. Our responsibility is to express an
opinion  on  these  financial  statements  and financial highlights based on our
audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to  obtain  reasonable  assurance  about  whether  the  financial statements and
financial  highlights  are  free  of  material  misstatement.  An audit includes
examining,  on  a test basis, evidence supporting the amounts and disclosures in
the  financial  statements  and  financial  highlights.  Our procedures included
confirmation  of securities owned as of December 31, 1999 by correspondence with
the  custodian  and  brokers.  An  audit  also includes assessing the accounting
principles  used  and  significant  estimates  made  by  management,  as well as
evaluating  the  overall  financial  statement presentation. We believe that our
audits provide a reasonable basis for our opinion.

In  our  opinion,  the financial statements and financial highlights referred to
above  present  fairly, in all material respects, the financial position of each
of  the respective series constituting Dreyfus Money Market Instruments, Inc. at
December  31, 1999, the results of their operations for the year then ended, the
changes  in their net assets for each of the two years in the period then ended,
and the financial highlights for each of the indicated years, in conformity with
accounting principles generally accepted in the United States.

                                                              Ernst & Young LLP
New York, New York

February 7, 2000

                                                             The Fund


Dreyfus Money Market Instruments, Inc.

Government Securities Series

IMPORTANT TAX INFORMATION (Unaudited)

For  State  individual  income  tax  purposes,  the Government Securities Series
hereby designates 34.69% of the ordinary income dividends paid during its fiscal
year  ended  December  31,  1999  as attributable to interest income from direct
obligations  of  the  United  States.  Such  dividends are currently exempt from
taxation  for individual income tax purposes in most states, including New York,
California and the District of Columbia.


                                                           For More Information

                        Dreyfus

                        Money Market

                        Instruments, Inc.

                        200 Park Avenue

                        New York, NY 10166

                        Manager

                        The Dreyfus Corporation

                        200 Park Avenue

                        New York, NY 10166

                        Custodian

                        The Bank of New York

                        100 Church Street

                        New York, NY 10286

                        Transfer Agent &

                        Dividend Disbursing Agent

                        Dreyfus Transfer, Inc.

                        P.O. Box 9671

                        Providence, RI 02940

                        Distributor

                        Premier Mutual Fund Services, Inc.

                        60 State Street

                        Boston, MA 02109

To obtain information:

BY TELEPHONE Call 1-800-645-6561

BY MAIL  Write to:  The Dreyfus Family of Funds 144 Glenn Curtiss Boulevard
Uniondale, NY 11556-0144

BY E-MAIL  Send your request to [email protected]

ON THE INTERNET  Information can be viewed online or downloaded from:

http://www.dreyfus.com

(c) 2000 Dreyfus Service Corporation                              008-060AR9912





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