DUPONT E I DE NEMOURS & CO
424B3, 1995-09-08
PLASTIC MATERIAL, SYNTH RESIN/RUBBER, CELLULOS (NO GLASS)
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                                                Rule 424(b)(3)
                                                File No. 33-48128
 Pricing Supplement:  46
                                                 Dated  6-SEP-95
 (To Prospectus dated June 2, 1992, and
 Prospectus Supplement dated July 24, 1992)
 
                               
                   E. I. du Pont de Nemours and Company
                                 
                        Medium-Term Notes, Series F
                 Due Nine Months or More From Date of Issue
                              (Fixed Rate)

 DSE-CUSIP:  26353V BR9
          
 Principal Amount: $66,650,000.00	
 
 Interest Payment Dates:  1 May
                          1 November 
 
 Issue Price:             100.00
                                   
 Original Issue Date:  11-SEP-95   
                                   
 Maturity Date:        12-SEP-05   
                                   
 Interest Rate:            6.60%   
 
 Form: (X)  Book-Entry
       ( )  Certificated         
 
  
 -----------------------------------------------------------------
 
 Redemption: 

 	(X) The Notes cannot be redeemed prior to Maturity Date.
 
 	( ) The Notes may be redeemed prior to Maturity Date.
               Initial Redemption Date:
               Initial Redemption Price:
               Annual Redemption Price Reduction:
           
 Repayment:  

	(X) The notes cannot be repaid prior to Maturity Date.
 
	( ) The Notes may be repaid prior to Maturity Date.
               Initial Repayment Date:
               Initial Repayment Price:
               Annual Repayment Price Reduction:
 
 Discount Note:
 	( )Yes   (X)No
               Total Amount of OID:
               Yield to Maturity:
               Initial Accrual period OID:
           
 Agents' Commission: .60%

 Agents:  CS First Boston Corporation
          Goldman, Sachs & Co.
          Merrill Lynch & Co.
          Morgan Stanley & Co., Inc.             
          J. P. Morgan Securities, Inc.


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