SCHERING PLOUGH CORP
11-K, 1998-06-22
PHARMACEUTICAL PREPARATIONS
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               SECURITIES AND EXCHANGE COMMISSION
                     Washington, D.C.  20549
                                
                                
                                
                            Form 11-K
                                
                                
                                
         FOR ANNUAL REPORTS OF EMPLOYEE STOCK PURCHASE,
       SAVINGS AND SIMILAR PLANS PURSUANT TO SECTION 15(d)
             OF THE SECURITIES EXCHANGE ACT OF 1934
                                
                                
                                
                                
                                
    [X]   ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE
    SECURITIES EXCHANGE ACT OF 1934
    
    For the fiscal year ended December 31, 1997
                                
                               OR
                                
    [  ]   TRANSITION REPORT PURSUANT TO SECTION 15(d) OF
    THE SECURITIES EXCHANGE ACT OF 1934
    
    For the transition period from        to
                                
    Commission file number 2-84723
                                
                                
                                
                                
                                
                                
  THE SCHERING-PLOUGH PUERTO RICO EMPLOYEES' RETIREMENT SAVINGS
                              PLAN
                                
                                
                                
                   Schering-Plough Corporation
                        One Giralda Farms
                          P.O. Box 1000
                   Madison, New Jersey  07940
                                
                                

THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

TABLE OF CONTENTS


                                                             Page
                                                                 
INDEPENDENT AUDITORS' REPORT                                    1

FINANCIAL STATEMENTS:

 Statements of Net Assets Available for Benefits
  as of December 31, 1997 and 1996                              2

 Statement of Changes in Net Assets Available for Benefits
  for the Year Ended December 31, 1997                          3

 Notes to Financial Statements                                4 - 7


SUPPLEMENTAL SCHEDULES:                                      SCHEDULE

 Schedule of Assets Held for Investment Purposes
  December 31, 1997                                             I

 Schedule of Transactions in Excess of 5%
  of Plan Assets for the Year Ended December 31, 1997           II


EXHIBITS:

 Exhibit I                                        Independent Auditors' Consent







Supplemental schedules not included herein are omitted due to the
absence of conditions under which they are required.




INDEPENDENT AUDITORS' REPORT
 
 
The Schering-Plough Puerto Rico Employees' Retirement Savings
Plan:

We  have  audited  the  accompanying statements  of  net  assets
available  for  benefits  of  The  Schering-Plough  Puerto  Rico
Employees'   Retirement  Savings  Plan  (the   "Plan")   as   of
December 31, 1997 and 1996, and the related statement of changes
in net assets available for benefits for the year ended December
31, 1997.  These financial statements are the responsibility  of
the  Plan's  management.  Our responsibility is  to  express  an
opinion on these financial statements based on our audits.

We  conducted  our audits in accordance with generally  accepted
auditing  standards.  Those standards require that we  plan  and
perform  the audit to obtain reasonable assurance about  whether
the financial statements are free of material misstatement.   An
audit  includes examining, on a test basis, evidence  supporting
the  amounts  and disclosures in the financial  statements.   An
audit also includes assessing the accounting principles used and
significant estimates made by management, as well as  evaluating
the  overall financial statement presentation.  We believe  that
our audits provide a reasonable basis for our opinion.

In  our  opinion,  the financial statements  referred  to  above
present  fairly,  in  all  material  respects,  the  net  assets
available for benefits of the Plan as of December 31,  1997  and
1996,  and the changes in net assets available for benefits  for
the  year  ended December 31, 1997, in conformity with generally
accepted accounting principles.

Our  audits were conducted for the purpose of forming an opinion
on  the  basic  financial statements  taken  as  a  whole.   The
supplemental  schedules of Assets Held for  Investment  Purposes
and  Transactions in Excess of 5% of Plan Assets  are  presented
for  the  purpose of additional analysis and are not a  required
part  of  the  basic financial statements, but are supplementary
information  required  by the Department of  Labor's  Rules  and
Regulations  for  Reporting and Disclosure  under  the  Employee
Retirement Income Security Act of 1974. These schedules are  the
responsibility  of  the Plan's management. Such  schedules  have
been  subjected to the auditing procedures applied in our  audit
of  the basic 1997 financial statements and, in our opinion, are
fairly  stated  in  all  material respects  when  considered  in
relation to the basic financial statements taken as a whole.




_________________________________________
/s/  Deloitte & Touche LLP
      San Juan, Puerto Rico
      May 8, 1998


                                
<TABLE>


THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

STATEMENTS OF NET ASSETS AVAILABLE FOR BENEFITS
DECEMBER 31, 1997 AND 1996
<CAPTION>
                                                1997      1996
<S>                                        <C>         <C>
Vanguard Index Trust 500 Portfolio Fund    $ 5,228,436 $3,962,617

Vanguard Windsor Fund                        2,610,599  2,078,110

Vanguard Treasury Money Market Portfolio     1,296,315  1,299,422

Vanguard Fixed Income Securities Short-
   Term Corporate Portfolio Fund               364,238    396,869

Vanguard Wellington Fund                        97,393     43,719

Vanguard International Growth Portfolio
   Fund                                         69,267     64,787

Vanguard Explorer Fund                          52,893     40,699

   Total Vanguard Registered Investment
   Company Shares                            9,719,141  7,886,223

Schering-Plough Stock Fund                   2,448,942    690,264

Loan Fund                                    1,173,039    919,260

Participants' Receivables                            -    101,818

NET ASSETS AVAILABLE FOR BENEFITS          $13,341,122 $9,597,565





See notes to financial statements.
</TABLE>

<TABLE>
THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

STATEMENT OF CHANGES IN NET ASSETS AVAILABLE FOR BENEFITS
YEAR ENDED DECEMBER 31, 1997

<S>
ADDITIONS TO NET ASSETS ATTRIBUTED TO:
   Investment income:                            <C>
      Interest and dividends                     $   725,359

      Net appreciation in fair value
      of investments                               2,189,056

      Total                                        2,914,415

     Participants' contributions                   1,552,471

     Other receipts - rollovers and other
      transfers in                                     5,031

          Total additions                          4,471,917

DEDUCTIONS FROM NET ASSETS ATTRIBUTED TO:

     Benefit payments                                728,360

          Total deductions                           728,360

NET INCREASE                                       3,743,557

NET ASSETS AVAILABLE FOR BENEFITS:

Beginning of year                                  9,597,565

End of year                                      $13,341,122

See notes to financial statements.
</TABLE>



THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

NOTES TO FINANCIAL STATEMENTS



1. GENERAL
   
   The   Schering-Plough   Puerto  Rico  Employees'   Retirement
   Savings  Plan  (the  "Plan") is a defined  contribution  plan
   established  effective March 1, 1990.  The Plan  is  intended
   to  encourage  retirement savings by  eligible  employees  of
   Schering-Plough  Products, Inc. (the "Sponsor")  and  any  of
   its  affiliated  companies that adopts  the  Plan.   Vanguard
   Fiduciary  Trust Company ("VFTC"), the trustee,  is  a  trust
   company  incorporated under Chapter 10  of  the  Pennsylvania
   Banking  Code, and a wholly-owned subsidiary of The  Vanguard
   Group, Inc. ("Vanguard").
   
   All  Puerto Rico employees of Schering-Plough Products,  Inc.
   and   Schering-Plough  del  Caribe,  Inc.  are  eligible   to
   participate  in  the Plan on the date of  employment.   There
   were  944  and  957 participants in the Plan at December  31,
   1997  and 1996, respectively.  The participants may elect  to
   have their salary deferral contributions allocated to any  of
   the investment funds available under this Plan.
   

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
   
   Basis of Accounting
   The  financial  statements of the Plan are  prepared  on  the
   accrual   basis   in   accordance  with  generally   accepted
   accounting    principles   and   the   financial    reporting
   requirements  of the Employee Retirement Income Security  Act
   of 1974 ("ERISA").
   
   Investment Valuation and Income Recognition
   The  Plan's investments are stated at fair value.  Shares  of
   registered  investment companies are valued at quoted  market
   prices which represent the net asset value of shares held  by
   the Plan at year end.
   
   The  Schering-Plough  Stock Fund is  valued  using  the  unit
   accounting  method whereby a participant's account  value  is
   expressed  in  units of participation rather than  number  of
   shares  of  Schering-Plough common stock.   At  December  31,
   1997  and  1996,  there  were  4,369   and  2,359  units   of
   participation    in   the   Schering-Plough    Stock    Fund,
   respectively.  The net asset value per unit was  $560.51  and
   $292.66 at December 31, 1997 and 1996, respectively.
   
   Purchases  and sales of securities are recorded on  a  trade-
   date  basis.   Interest  income is recorded  on  the  accrual
   basis.   Dividends are recorded on the ex-dividend date,  and
   reinvested in Schering-Plough common stock units.
   
   Payment of Benefits
   Benefit payments are recorded when paid.
   


3. PLAN DESCRIPTION
   
   The  following  is  a  description of the  Plan  for  general
   information purposes.  Participants should refer to the  Plan
   document for more complete information.
   
   Salary Deferral Contributions
   The  Plan  is designed to permit eligible employees to  elect
   to  have a portion of their salary contributed to the Plan on
   their  behalf ("salary deferral contributions").   Under  the
   provisions  of  the  Plan, salary deferral contributions  can
   range  from  1%  to  10%  of  the  employee's  earnings,   in
   increments  of  1%,  subject to certain limitations.   Salary
   deferral  contributions and any earnings accrued thereon  are
   fully and immediately vested to the participant.
   
   Participant Accounts
   Each    participant's   account   is   credited   with    the
   participant's contribution and allocations of Plan  earnings.
   Allocations  are  based on participant  earnings  or  account
   balances,  as  defined.  Participants have  a  nonforfeitable
   right  to  their  contributions plus actual earnings  thereon
   which vest fully and immediately.
   
   Investment Options
   Upon  enrollment in the Plan, a participant may direct  their
   contributions  into any of the following Vanguard  investment
   options:
   
   -     Index  Trust 500 Portfolio Fund - Designed  to  provide
     returns which correspond to the performance of Standard & Poor's
     500 Composite Stock Price Index.
     
   -    Windsor Fund - Primarily equity securities with the
objective of providing long-term capital growth.
   -    Treasury Money Market Portfolio - Exclusively U.S. Treasury
securities with maturities of 13 months or less with the
objective of providing current income based on current market
interest rates, with preservation of principal and liquidity.
   -    Fixed Income Securities Short-Term Corporate Portfolio Fund
       - A diversified portfolio primarily consisting of short-term
corporate bonds.
- -    Wellington Fund - Primarily equity and fixed income
securities with the objective of providing current income and
capital appreciation.
- -    International Growth Portfolio Fund - A non-U.S. equity
portfolio, primarily investing in securities of issuers within
Europe, Asia and the Far East.
- -    Explorer Fund - Primarily equity securities of smaller
companies with the objective of providing above average capital
appreciation but with a potentially higher level of risk.
   Schering-Plough Stock Fund
   Invests  in  Schering-Plough  Corporation  common  shares  to
   provide   the   possibility  of  long-term   growth   through
   increases  in  the  market  value  of  the  shares  and   the
   reinvestment  of dividends.  Participants are  limited  to  a
   maximum  investment  election of 50% of the  Salary  Deferral
   Contributions in this fund.
   
   Loan Fund
   The  Plan  allows participants to borrow against  their  fund
   accounts  up to a maximum of the lesser of one half of  their
   account  or $50,000.  These loans, which are secured  by  the
   participants' individual fund accounts, bear a fixed rate  of
   interest  as  determined to be reasonable  by  The  Schering-
   Plough  Puerto  Rico Employees' Savings Plan  Committee,  and
   are  repayable over periods not exceeding five years,  except
   loans  relating to a principal residence which are  repayable
   over a period not to exceed 20 years.
   
   Payment of Benefits
   On termination of service due to retirement or disability,  a
   participant may elect to receive either a lump-sum amount  or
   annual installments not to exceed the life expectancy of  the
   participant  or the life expectancy of the beneficiary.   For
   termination  of service due to other reasons,  a  participant
   may   receive  the  value  of  the  account  as  a  lump  sum
   distribution.   Distribution  of  all  or  a  portion  of   a
   participant's  account, prior to termination  of  employment,
   may  be  granted  by  the Company in the  case  of  financial
   hardship.
   

4. PLAN TERMINATION
   
   Although  it  has  not expressed any intent  to  do  so,  the
   Sponsor  has  the  right to terminate  the  Plan  subject  to
   provisions of ERISA.
   

5. TAX STATUS
   
   In  March  1992, the Plan received a favorable  determination
   letter  issued by the Puerto Rico Department of  Treasury  as
   to  the Plan's qualified status under Sections 165(a) and (e)
   of  the  Puerto Rico Income Tax Act of 1954, as amended.   As
   long  as  the Plan is qualified under Puerto Rico income  tax
   laws  and  regulations, participants will  not  be  taxed  on
   salary-deferred  contributions or on investment  earnings  on
   such  contributions  at  the  time  such  contributions   and
   investment  earnings are received by the  trustee  under  the
   Plan,  but  will be subject to tax thereon at  such  time  as
   they receive distributions from the Plan.
   

6. ADMINISTRATION OF PLAN ASSETS
   
   Contributions  are  held and managed by  the  trustee,  VFTC,
   which  invests  cash received, interest and  dividend  income
   and  makes  distributions to the participants.   The  trustee
   also administers the collection of interest and principal  on
   the participant loans.
   
   Certain  administrative functions are performed  by  officers
   or  employees  of the Sponsor.  No such officer  or  employee
   receives compensation from the Plan.
   
   All plan administration expenses are borne by the Sponsor.
   


7. FUND INFORMATION
   
   Investment income, contributions and benefit payments are as follows for  the
   year ended December 31, 1997:
   
<TABLE>
<CAPTION>

                                           Vanguard                                                
                                            Fixed                                                  
                                            Income                                         
            Vanguard            Vanguard.  Securiti           Vanguard                                 
             Index              Treasury   es Short-           Inter-          Scheri              
             Trust    Vanguard    Money      Term    Vanguard  nationa  Vangua    ng-               
              500     Windsor    Market    Corporate Wellingt     l       rd    Plough   Loan       
            Portfolio    Fund    Portfolio           on Fund    Growth  Explor   Stock   Fund    Total
             Fund                         Portfolio           Portfol    er     Fund
                                             Fund            io Fund   Fund
<S>         <C>        <C>       <C>       <C>      <C>       <C>      <C>     <C>     <C>     <C>
Investment
Income:
Interest                                                                                     
   and                     
dividends   $108,701   $407,002   $65,533  $23,038  $7,959    $2,835   $5,072   24,044  $81,175 $725,359
           
  Net                                                                                          
appreciati                                                                                     
on                                                                                             
(depreciat                                                                                     
ion) in                                                                                        
fair                                                                                           
value of   1,197,867     50,700     -        1,838    6,805     1,736    (313) 930,423     -    2,189,056
investment                                                                    
s
                                                                                               
Total                                                                                          
Investment                                                                                     
Income    $1,306,568   $457,702   $65,533  $24,876  $14,764    $4,571  $4,759 $954,467  $81,175 $2,914,415
            
                                                                                               
Participants'                                                                                     
Contributi  $546,668   $412,383  $159,163  $73,658  $33,304   $28,258  $16,566 $282,471    -    $1,552,471
ns
                                                                                               
Other                                                                                          
receipts -                                                                                     
Rollovers                                                                                      
and         
Transfers   $ 1,258      $1,258     -         -          -         -        -    $2,515    -        $5,031
In
                                                                                               
Benefits                                                                                       
Paid to                         
Participan  $264,951  $143,338  $140,501  $36,860    $2,493  $22,071     $495   $67,679 $49,972   $728,360
ts
                                                                                               

</TABLE>


                                     ******

<TABLE>
THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

ITEM 27a - SCHEDULE OF ASSETS HELD FOR INVESTMENT PURPOSES
DECEMBER 31, 1997

<CAPTION>
Identity                        Shares/                  Current
of issue          Participants   Units        Cost        Value

<S>               <C>        <C>        <C>          <C>
Vanguard Index
Trust 500
Portfolio Fund*    713          58,049   $3,194,508  $5,228,436 (1)

Vanguard Windsor
Fund*              529         153,746    2,483,929   2,610,599 (1)

Vanguard Treasury
Money Market
Portfolio*         398       1,296,315    1,296,315   1,296,315 (1)

Vanguard Fixed
Income Securities
Short-Term
Corporate
Portfolio Fund*    179          33,695     361,577      364,238

Vanguard
Wellington Fund*    71           3,307      91,213       97,393

Vanguard
International
Growth Portfolio
Fund*               59           4,226      71,981       69,267

Vanguard Explorer
Fund*               52             956      53,145       52,893

Schering-Plough
Stock Fund         420          4,369(2)  1,515,585   2,448,942 (1)

Outstanding loan
balance -various
loans; 7% to 10%,
due in one year to
five years         361                    1,173,039  1,173,039(1)

Total investments                       $10,241,292  $13,341,122


*Registered Investment Company.

(1) Indicates investment represents five percent or more of the
net assets available for benefits.

(2) Represents Schering-Plough Stock Fund units.

</TABLE>

<TABLE>
THE SCHERING-PLOUGH PUERTO RICO
EMPLOYEES' RETIREMENT SAVINGS PLAN

ITEM 27D - SCHEDULE OF TRANSACTIONS IN EXCESS OF 5% OF PLAN ASSETS
YEAR ENDED DECEMBER 31, 1997

<CAPTION>

Identity             Cost of       Number of     Proceeds      Number   Net
of Issue            Purchases      Purchases     From Sales    of Sales Gain

<S>                <C>             <C>         <C>             <C>          <C>
Vanguard
Index Trust
500 Portfolio
Fund               $1,069,847           84     $1,001,894         105  $345,185

Vanguard Windsor
Fund                1,192,652           84        710,863          94  122,025

Vanguard Treasury
Money Market
Portfolio             541,736          110        544,843          98  -

Schering-Plough
Stock Fund          1,084,017          115        255,762          54  78,051

</TABLE>


                                        
EXHIBIT I









INDEPENDENT AUDITORS' CONSENT
 
 
We  consent  to  the incorporation by reference in  Registration
Statements No. 2-83963, No. 33-19013, No. 33-50606 and No.  333-
30331 on Form S-8, Registration Statement No. 333-853 on Form S-
3,  Post-Effective Amendment No. 1 to Registration Statement No.
2-84723  on  Form  S-8,  Post-Effective  Amendment  No.   1   to
Registration  No. 2-80012 on Form S-3, Post-Effective  Amendment
No.  1  to  Registration Statement No. 2-77740 on Form  S-3  and
Registration Statements No. 333-12909 and No. 333-30355 on  Form
S-3  of  our  report dated May 8, 1998 appearing in this  Annual
Report   on  Form  11-K  of  The  Schering-Plough  Puerto   Rico
Employees'  Retirement Savings Plan for the year ended  December
31, 1997.





__________________________________________
/s/ Deloitte & Touche LLP
     San Juan, Puerto Rico
     June 17, 1998



                           SIGNATURES
                                
Pursuant to the requirements of the Securities Exchange Act of
1934, the trustees (or other persons who administer the plan)
have duly caused this Annual Report to be signed on its behalf
by the undersigned hereunto duly authorized.

  Schering-Plough Puerto Rico Employees' Retirement Savings Plan

Date:  June 17, 1998               By  /s/ Vincent Sweeney
                                           Vincent Sweeney
                                           Plan Administrator





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