BIO RESPONSE INC
10QSB, 1999-11-12
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                                   FORM 10-QSB

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D. C. 20549

(Mark One)
     [X]    QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE
            SECURITIES EXCHANGE ACT OF 1934

            For the Quarter Ended September 30, 1999

                                       OR

     [ ]    TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
            SECURITIES EXCHANGE ACT OF 1934

                          Commission file number 0-9201

                               BIO-RESPONSE, INC.
               (Exact name of Issuer as specified in its charter)


                Delaware                           59-3453151
               (State or                       (I.R.S. Employer
          other jurisdiction of                Identification No.)
     incorporation or organization)

                             1612 N. Osceola Avenue
                            Clearwater, Florida 33755
                         (Address of principal offices)

                                 (727) 443-3434
               (Issuer's telephone number, including area code)

      Indicate  by check  mark  whether  the  Issuer  (1) has filed all  reports
required to be filed by Section 13 or 15 (d) of the  Securities  Exchange Act of
1934 during the preceding 12 months (or for such shorter  period that the Issuer
was  required  to file such  reports)  and (2) has been  subject to such  filing
requirements for the past 90 days.
                                                             Yes  [X]  No  [   ]

      State the number of shares  outstanding of each of the issuer's classes of
common stock, as of the latest practicable dates.

         Title of Each Class                Outstanding at September 30, 1999

   Common Stock, $0.004 Par Value               800,000 - see financial note
                                                4 for more explanation


<PAGE>


                                TABLE OF CONTENTS




PART I   FINANCIAL INFORMATION                                            PAGE

ITEM 1   Financial Statements

         Balance Sheets as of September 30, 1999
          and September 30, 1998                                            3

         Statements of Income for the Three  Month
          Periods Ended September 30, 1999 and September 30, 1998.          4

         Statements of Cash Flow for the Three  Month
          Periods Ended September 30, 1999 and September 30, 1998.          5

         Notes to Financial Statements                                      6

ITEM 2   Management's Discussion and Analysis of
         Financial Condition and Results of Operations                      8


PART II  OTHER INFORMATION                                                 12

         SIGNATURES                                                        12


<PAGE>


                               BIO-RESPONSE, INC.
                            (a Dormant State Company)
                                  Balance Sheet
                    September 30, 1999 and September 30, 1998
                                   (unaudited)



                                             06/30/99     06/30/98
Assets


Organization Cost .......................   $       0    $       0

 Total Assets ...........................           0            0

Liabilities and Shareholder's Equity ....           0            0

Stockholders' Equity ....................           0            0

Common Stock par value at $.004 per share
25,000,000 shares authorized,
800,000 shares issued and outstanding(4)            0            0
Net Income/Loss for Period ..............      (7,906)      (4,935)
Additional Paid in Capital ..............       7,906        4,935
Retained  Earnings (Deficit) ............    (106,834)     (43,921)
                                            ---------    ---------


Total Shareholders' Equity ..............           0            0
                                            ---------    ---------

Total Liabilities and Shareholders Equity   $       0    $       0
                                            =========    =========











                See accompanying notes to financial statements



<PAGE>


                               BIO-RESPONSE, INC.
                            (a Dormant State Company)
                            Statements of Operations

       for the periods ending September 30, 1999 and September 30, 1998
                                   (unaudited)


                                      For Three Months Ended

                                      1999             1998
                                   09 -30-99        09 -30-98
                                    -------          --------

Revenues .....................   $           0    $           0

Expenses
Administrative Expenses ......   $       7,906    $       4,935
Filing Fees ..................   $           0    $           0

Net Income/Loss for the period   $      (7,906)   $      (4,935)
                                 =============    =============










                See accompanying notes to financial statements


<PAGE>





                               BIO-RESPONSE, INC.
                            (a Dormant State Company)
                            Statements of Cash Flows
               for three months ended September 30, 1999 and 1998
                                   (unaudited)


                                        For Three Months Ended

                                         09-30-99          09-30-98
                                         --------          --------

Cash Flows from Operating Activities
 Net Income ........................   $      (7,906)   $      (4,935)

Net Cash Provided (used) /
By Operating Activities ............               0                0


Expenses Paid by Capston ...........           7,906            4,935

Net Increase (Decrease) in Cash ....               0                0
Cash at Beginning of Period ........               0                0
                                       -------------    -------------

Cash at End of Period ..............   $           0    $           0
                                       =============    =============










                See accompanying notes to financial statements


<PAGE>



                               BIO-RESPONSE, INC.
                            (A Dormant State Company)


                               September 30, 1999

Note 1. HISTORY OF THE COMPANY

BIO-RESPONSE,  Inc., (A Dormant State Company),  was incorporated on 1972, under
the laws of the State of  Delaware.  The  Company  conducted  an initial  public
offering  of its  Common  Stock  in  January,  1979  and in  connection  with an
application  to list its Common  Stock on the NASDAQ  system,  the Company  also
registered its Common Stock pursuant to Section 12(g) of the Securities Exchange
Act of 1934.

On September 14, 1989,  the Company filed a voluntary  petition under Chapter 11
of the Bankruptcy Act (Case No. 4-89-04159 N-3) in the U.S. Bankruptcy Court for
the Northern  District of California.  On September 15, 1995, the Company's case
under  Chapter 11 was closed  under court order.  As a result of the  bankruptcy
case, all assets of the Company were overseen by the Trustee in Bankruptcy.  The
assets  were  sold  and the  Company  ceased  all  operations.  The  Trustee  in
Bankruptcy  effected an orderly  liquidation  of  corporate  assets and used the
proceeds to repay the Company's  creditors.  On September 15, 1995 the Company's
case under  Chapter  11 was  closed by an order of the Court and the  Trustee in
Bankruptcy was  discharged.  As a result of the  Bankruptcy,  the Company has no
assets, liabilities, management or ongoing operations and has not engaged in any
business activities for a a decade.

Note 2. RESTORATION OF CORPORATE STATUS

On June 10, 1996,  acting in its capacity as the holder of 2000 shares (0.0002%)
of the Company's common stock, and without first receiving the consent, approval
or  authorization  of any other  person  associated  with the  Company,  Capston
Network  Company  effected a renewal,  revival and  restoration of the Company's
certificate of incorporation  pursuant to Section 312 of the General Corporation
Law of Delaware.  Thereafter, Capston filed a 10-K for the years ending December
31,  1990-1996,  and a Proxy Statement  seeking approval and ratification of its
actions,  along  with  authorization  to seek a  suitable  business  combination
transaction.  This proxy  statement was ultimately  distributed to the Company's
stockholders  and the  proposals  therein  were  approved  by the  holders  of a
majority of the Company's issued and outstanding shares.

Under the terms of the original Proxy Statement,  Capston was authorized to seek
a suitable  business  combination  transaction  on behalf of the  Company and to
submit  the  terms  of any  proposed  business  combination  transaction  to the
Company's  stockholders for their approval.  Capston did not receive and was not
entitled  to  receive  any  equity  interest  in the  Company as a result of its
actions  prior to the date of the Proxy  Statement.  Moreover,  Capston  was not
entitled  to  reimbursement  for any  expenses  incurred  by it on behalf of the
Company  except  to  the  extent  that  the  terms  of  a  business  combination
transaction  provided for the reimbursement of such expenses.  However,  because
Sally Fonner is both the  President  of  BIO-RESPONSE  and Capston,  prior Staff
Accounting Bulletins require under generally accepted accounting  principles the
treatment of debiting the expenses with corresponding credit to paid-in capital.
Future  expenses of Capston or others will be treated this way.  These  expenses
are actual cash  expenditures  and do not reflect any costs  associated with the
operation of Capston nor any personnel time or cost.


<PAGE>



Note 3. FUTURE EXPENSES

Capston will  continue to extend  administrative  expenses to keep  BIO-RESPONSE
current  with  its  reporting  requirements,  keeping  the  Corporation  in good
standing,  any required proxy solicitation or acquisition efforts. These amounts
should not exceed another  $100,000 in  out-of-pockets  costs.  In addition,  as
approved, and as a result of a suitable acquisition, additional fees paid for by
issuance of equity  position  would be for:  (i) up to  4,500,000  shares for an
acquisition(s),  (ii) up to 5% of the  acquisition  for a finder's fee and (iii)
legal/consulting fees.


Note 4.  OUTSTANDING COMMON SHARES

On March  31,  1999,  the  Company  filed an  amendment  to its  certificate  of
incorporation  that was  intended to  implement  the 30.5885 to 1 reverse  split
approved by the  stockholders  in 1997.  In  connection  with the filing of this
Certificate  of  Amendment,  the Company's  sole  director  elected to implement
certain rounding  provisions to maximize the number of round-lot holders.  While
the implementation of these rounding provisions was based on the advice of legal
counsel,  the Company was  subsequently  advised by Delaware  counsel  that such
rounding  provisions were not in compliance  with Delaware law. In addition,  it
was  discovered  that a  clerical  mistake  had been  made in the  filing on the
original reverse formula (it was filed as a 32 to 1 reverse split). Accordingly,
on October 25, 1999 the Company filed a corrected  Amendment to its  Certificate
of  Incorporation  which  implemented  the precise reverse split approved by the
stockholders,  Concurrently,  legal  counsel  for  the  Company  surrendered  an
aggregate of 27,904 shares of Common Stock to the Company's  transfer  agent for
cancellation  in order to (1) offset the over  issuance  of shares to certain of
the Company's  stockholders who benefited from the rounding  provisions prior to
the  filing of the a  corrected  Amendment,  and (2)  bring the total  number of
shares issued and outstanding down to 800,000.



<PAGE>


Item 2.     Management  Discussion  and  Analysis of Financial  Condition  and
            Results of Operations.

Financial Condition

      BIO-RESPONSE has no operations,  assets or liabilities.  Expenses incurred
to keep it in good standing with  governmental and regulatory  bodies,  maintain
the  transferability  of its stock and interact with  stockholders,  are paid by
Capston.

Corporate Background Information

       BIO-RESPONSE  conducted an initial public offering of its Common Stock in
September,  1979  pursuant  to a  Form  S-2  Registration  Statement  under  the
Securities Act of 1933 (the "Securities Act"). In connection with an application
to list its Common Stock on the NASDAQ system,  the Company also  registered its
Common Stock  pursuant to Section 12(g) of the  Securities  Exchange Act of 1934
(the "Exchange Act"). The Company remained current with respect to its reporting
obligations under the Exchange Act until 1990.

       After  pursuing  its  business for several  years,  BIO-RESPONSE  filed a
voluntary petition under Chapter 11 of the Bankruptcy Act on September 14, 1989.
This  proceeding  was filed in with the U.S.  Bankruptcy  Court for the Northern
District of California and designated as Case # 4-89-04159 N-3. On September 15,
1995 the Company's case under Chapter 11 was closed by an order of the Court. As
a result of the Bankruptcy, the Company has no assets,  liabilities,  management
or ongoing  operations  and has not engaged in any business  activities for well
over a half of a decade.

      During the pendancy of the Bankruptcy,  the Company did not file franchise
tax returns with and pay the required  franchise taxes to the State of Delaware.
As a  result,  the  Company's  corporate  charter  was  revoked  by order of the
Secretary of State of the State of Delaware on August 30, 1991.  Similarly,  the
Company  did not file  with the SEC  either  (a) the  regular  reports  that are
required of all companies  that have  securities  registered  under the Exchange
Act, or (b) a certification  on Form 15 terminating its  registration  under the
Exchange Act. As a result,  the Company remained a Registrant under the Exchange
Act but was seriously delinquent in its SEC reporting obligations.  According to
Lumiere Securities,  the last published quotation for the Company's Common Stock
was posted by M. H. Meyerson & Co., Inc., one of the Company's market makers, on
September  30, 1998. At this time,  the published  quote was $0.03 bid and $0.10
asked.

      Acting in its capacity as a Stockholder of the Company,  and without first
receiving any consent,  approval or  authorization  of any officer,  director or
other  Stockholder  of the  Company,  Capston  effected a renewal,  revival  and
restoration of the Company's  certificate of  incorporation  pursuant to Section
312 of the General Corporation Law of the State of Delaware. In general, Section
312  provides  that any  corporation  may  "procure an  extension,  restoration,
renewal or revival of its  certificate of  incorporation,  together with all the
rights, franchises,  privileges and immunities and subject to all of its duties,
debts  and  liabilities  which  had been  secured  or  imposed  by its  original
certificate  of   incorporation"   upon  compliance   with  certain   procedural
requirements.

      After  reviewing the applicable  files,  Capston  determined that the only
debt of the Company that was  "secured or imposed by its  original  certificate"
was the obligation of BIO-RESPONSE to pay its Delaware taxes. Therefore, Capston
paid all past due  franchise  taxes on behalf of the  Company  and then  filed a
Certificate  of Renewal,  Revival,  Extension and  Restoration  of the Company's
Certificate  of  Incorporation  on behalf  of the  Company  under the  authority
granted  by  Section  312(h).  The total  out-of-pocket  costs  paid by  Capston
incurred in connection with the  restoration of the Company's  charter was $450.
This  Certificate was filed in the office of the Secretary of State of the State
of  Delaware on December  26, 1996 and at the date of this Proxy  Statement  the
Company is lawfully  incorporated,  validly  existing and in good standing under
the laws of the State of Delaware.


Proposed Operations

      While the  Company  has no  assets,  liabilities,  management  or  ongoing
operations and has not engaged in any business activities, Capston believes that
it may be  possible  to recover  some  value for the  Stockholders  through  the
adoption and  implementation  of a Plan whereby the Company will be restructured
as a "clean  public  shell" for the purpose of effecting a business  combination
transaction  with a  suitable  privately-held  company  that has  both  business
history and operating assets.

      Capston   believes   the   Company   will  offer   owners  of  a  suitable
privately-held  company  the  opportunity  to  acquire a  controlling  ownership
interest in a public company at substantially  less cost than would otherwise be
required to conduct an initial  public  offering.  Nevertheless,  Capston is not
aware of any  empirical  statistical  data that would  independently  confirm or
quantify  Capston's  beliefs  concerning  the  perceived  value of a  merger  or
acquisition transaction for the owners of a suitable privately-held company. The
owners of any existing  business  selected for a business  combination  with the
Company  will  incur  significant  costs and  expenses,  including  the costs of
preparing the required business  combination  agreements and related  documents,
the costs of  preparing a Current  Report on Form 8-K  describing  the  business
combination transaction and the costs of preparing the documentation  associated
with any future  reporting  under the Exchange Act and  registrations  under the
Securities Act.

      The Plan is approved by the Stockholders. The Company is fully reactivated
and ready to be used as a  corporate  vehicle to seek,  investigate  and, if the
results of such  investigation  warrant,  effect a business  combination  with a
suitable privately-held company or other business opportunity presented to it by
persons  or  firms  that  seek  the  perceived  advantages  of a  publicly  held
corporation. The business operations proposed in the Plan are sometimes referred
to  as  a  "blind  pool"  because  Stockholders  will  not  ordinarily  have  an
opportunity  to analyze  the various  business  opportunities  presented  to the
Company,  or to  approve or  disapprove  the terms of any  business  combination
transaction  that  may be  negotiated  by  Capston  on  behalf  of the  Company.
Consequently,  the Company's  potential success will be heavily dependent on the
efforts and  abilities of Capston and its officers,  directors and  consultants,
who will have virtually unlimited  discretion in searching for,  negotiating and
entering  into a business  combination  transaction.  Capston and its  officers,
directors and consultants have had limited  experience in the proposed  business
of the Company. Although Capston believes that the Company will be able to enter
into a business  combination  transaction during 1999, there can be no assurance
as to how much time will elapse before a business  combination  is effected,  if
ever.  The  Company  will not  restrict  its  search to any  specific  business,
industry or geographical location, and the Company may participate in a business
venture of virtually any kind or nature.

      Capston and its officers,  directors and  consultants  anticipate that the
selection  of a  business  opportunity  for  the  Company  will be  complex  and
extremely risky.  Because of general economic  conditions,  rapid  technological
advances  being made in some  industries,  and  shortages of available  capital,
Capston believes that there are numerous  privately-held  companies  seeking the
perceived benefits of a publicly traded corporation. Such perceived benefits may
include  facilitating  debt financing or improving the terms on which additional
equity or may be sought, providing liquidity for the principals of the business,
creating a means for providing  incentive  stock options or similar  benefits to
key employees, providing liquidity for all stockholders and other factors.

      Potential  business  opportunities may occur in many different  industries
and at  various  stages  of  development,  all of  which  will  make the task of
comparative  investigation and analysis of such business opportunities extremely
difficult  and  complex.  Capston  anticipates  that the Company will be able to
participate in only one business venture. This lack of diversification should be
considered a  substantial  risk  inherent in the Plan because it will not permit
the  Company to offset  potential  losses from one  venture  against  gains from
another.  Moreover,  due to the  Company's  lack  of any  meaningful  financial,
managerial or other  resources,  Capston believes the Company will not be viewed
as a suitable business  combination  partner for either developing  companies or
established business that are in need of substantial additional capital.


Acquisition of Opportunities

      In implementing a particular business combination transaction, the Company
may become a party to a merger,  consolidation,  reorganization,  joint venture,
franchise or licensing agreement with another corporation or entity. It may also
purchase stock or assets of an existing  business.  After the  consummation of a
business combination transaction,  it is likely that the present Stockholders of
the Company will only own a small minority  interest in the combined  companies.
In addition,  as part of the terms of the  acquisition  transaction,  all of the
Company's  officers and directors will ordinarily  resign and be replaced by new
officers  and  directors  without a vote of the  Stockholders.  Capston does not
intend to obtain the  approval of the  Stockholders  prior to  consummating  any
acquisition other than a statutory merger that requires a Stockholder vote.
      It is  anticipated  that any securities  issued in a business  combination
transaction  will be issued in reliance on exemptions  from  registration  under
applicable Federal and state securities laws. In some circumstances, however, as
a  negotiated  element  of a  business  combination,  the  Company  may agree to
register such securities either at the time the transaction is consummated or at
some  specified  time  thereafter.   The  issuance  of  substantial   additional
securities and their potential sale into any trading market that may develop may
have a depressive effect on such market. While the actual terms of a transaction
to which the Company may be a party cannot be predicted, it may be expected that
the parties to the  business  transaction  will find it  desirable  to avoid the
creation of a taxable event and thereby structure the acquisition in a so called
"tax  free"  reorganization  under  Sections  368(a)(1)  or 351 of the  Internal
Revenue  Code of 1986,  as amended  (the  "Code").  In order to obtain  tax-free
treatment  under the Code,  it may be  necessary  for the owners of the acquired
business to own 80% or more of the voting stock of the surviving entity. In such
event,  the stockholders of the Company would retain less than 20% of the issued
and  outstanding  shares  of the  combined  companies,  which  could  result  in
significant dilution in the equity of such stockholders.  The Company intends to
structure  any business  combination  in such manner as to minimize  Federal and
state tax consequences to the Company and any target company.

      As  part   of  the   Company's   investigation   of   potential   business
opportunities,   Capston  and  its  officers,  directors  and  consultants  will
ordinarily  meet  personally  with  management and key personnel,  may visit and
inspect  material  facilities,  obtain  independent  analysis or verification of
certain information  provided,  check reference of management and key personnel,
and take other reasonable investigative measures, to the extent of the Company's
limited  resources  and  Capston's  limited  expertise.  The manner in which the
Company  participates  in an  opportunity  will  depend  on  the  nature  of the
opportunity,  the respective  needs and desires of the Company and other parties
and the relative negotiating strength of the Company and such other management.

      With  respect  to any  business  combination  negotiations,  Capston  will
ordinarily  focus  on  the  percentage  of  the  Company  which  target  company
stockholders  would  acquire in  exchange  for their  ownership  interest in the
Target Company.  Depending upon, among other things, the target company's assets
and liabilities,  the Company's  stockholders  will in all likelihood only own a
small  minority  interest  in the  combined  companies  upon  completion  of the
business  combination  transaction.  Any  business  combination  effected by the
Company can be expected to have a significant  dilutive effect on the percentage
of shares held by the Company's current Stockholders.

      Upon  completion of a business  combination  transaction,  there can be no
assurance that the combined  companies will have  sufficient  funds to undertake
any   significant   development,   marketing   and   manufacturing   activities.
Accordingly,  the combined  companies may be required to either seek  additional
debt or equity  financing or obtain funding from third parties,  in exchange for
which the combined  companies  might be required to issue a  substantial  equity
position.  There is no  assurance  that the combined  companies  will be able to
obtain additional financing on terms acceptable to the combined companies.

      It  is   anticipated   that  the   investigation   of  specific   business
opportunities   and  the   negotiation,   drafting  and  execution  of  relevant
agreements,  disclosure documents and other instruments will require substantial
management time and attention and substantial  costs for accountants,  attorneys
and others.  If a decision  is made not to  participate  in a specific  business
opportunity  the  costs  incurred  in the  related  investigation  would  not be
recoverable.  Furthermore, even if an agreement is reached for the participation
in a specific business  opportunity,  the failure to consummate that transaction
may result in the loss of the Company of the related costs incurred.

Exemption from Rule 419

      As an existing  Registrant under the Exchange Act, the Company's  proposed
activities  are not subject to SEC Rule 419 which was adopted to strengthen  the
regulation  of "blind  pool"  companies  which  Congress  has found to have been
common  vehicles  for fraud and  manipulation  in the penny  stock  market.  The
Company is not  subject  to Rule 419  because  it is not  offering  stock to the
public  in  an  offering  registered  under  the  Securities  Act.  Accordingly,
Stockholders  are not entitled to the  substantive  protection  provided by Rule
419.






<PAGE>




PART II - OTHER INFORMATION


ITEM 1.  LEGAL PROCEEDINGS


         NONE


ITEM 2.  CHANGES IN SECURITIES


         NONE


ITEM 3.  DEFAULTS ON SENIOR SECURITIES

         NONE


ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS


         NONE


ITEM 5.  OTHER INFORMATION

         NONE


ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

         A. Exhibits

            3.1 (I) Corrected Certificate of Amendment filed October 25, 1999

         B. Reports on Form 8-K

            NONE





                                   SIGNATURES

      Pursuant to the  requirements  of the Securities and Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                          BIO-RESPONSE, INC.


                                                             /s/
                                          ---------------------------------
                                          Sally A. Fonner
                                          Chief Executive Officer
                                          Dated: November 11, 1999


                                                             /s/
                                          ---------------------------------
                                          Sally A. Fonner
                                          Chief Financial Officer
                                          Dated: November 11, 1999


<PAGE>


                                   Exhibit 3.1


                                    CORRECTED
                           CERTIFICATE OF AMENDMENT OF
                               BIO-RESPONSE, INC.


     BIO-RESPONSE,  Inc., a  corporation  organized  and  existing  under and by
virtue of the General Corporation Law of the State of Delaware,


     DOES HEREBY CERTIFY:


     1. The name of the corporation is BIO-RESPONSE, Inc.


     2. A Certificate of Amendment (the  "Certificate  of Amendment")  was filed
with the Secretary of State of the State of Delaware on March 31, 1999 under the
previous  name  of  the  corporation,  BIO-RESPONSE,  INC.,  which  contains  an
inaccurate record of the corporate action taken therein, and said Certificate of
Amendment  requires  correction as permitted by subsection (f) of Section 103 of
the General Corporation Law of the State of Delaware.


     3. The Certificate of Amendment  incorrectly states that the amendments set
forth therein were approved by the stockholders of the corporation, when in fact
the  amendment  to for the "round lot  holder",  (any one  holding 100 shares or
more),  which kept them from being  reduced  below that status,  had not been so
approved by the stockholders and the reverse stock split referenced  therein had
been approved by the stockholders at a 30.5885 to 1 ratio rather than at a 32 to
1 ratio with only rounding for fractional shares.


     4.  The  Certificate  of  Amendment  is  therefore  amended  to read in its
corrected form as follows:


                                AMENDMENT TO THE
                         CERTIFICATE OF INCORPORATION OF
                               BIO-RESPONSE, INC.


               BIO-RESPONSE,   Inc.   (the   "Corporation"),   pursuant  to  the
          requirements of the General  Corporation Law of the State of Delaware,
          as amended ("GCLD"), hereby certifies:


               1. The amendment to the  Certificate of  Incorporation  set forth
          herein was duly adopted in accordance  with Section 242 of the GCLD by
          resolution of the Corporation's  Board of Directors,  submitted to the
          Corporation's  stockholders  for their  approval,  and  approved  by a
          majority vote of the  Corporation's  stockholders at a meeting called,
          noticed and held on the 10th day of March,  1997 and finalized on July
          29, 1997 after several adjournments of less than 30 days each.


               2. The  number of shares of the  Corporation  outstanding  at the
          time of such  adoption  and the  number  of  shares  entitled  to vote
          thereon  was NINE  MILLION,  ONE  HUNDRED  SEVENTY-SIX  THOUSAND  FIVE
          HUNDRED  FIFTY-FOUR  (9,176,554)  shares of common  stock (the "Common
          Stock").  The  holders  of FIVE  MILION,  THIRTY-NINE  THOUSAND,  NINE
          HUNDRED THIRTY-FOUR (5,039,934) shares of Common Stock were present at
          the meeting in person or by proxy and each of the amendments set forth
          herein was approved by the holders of a majority of the  Corporation's
          issued and outstanding shares of Common Stock.


               3. The effective  date and time of the  Certificate  of Amendment
          shall be 5 p.m. EST on April 2, 1999.


               4. Article Fourth of the Certificate of  Incorporation  is hereby
          amended to read in its entirety as follows:


                                 ARTICLE FOURTH
                               AUTHORIZED CAPITAL


               The  Corporation  shall be  authorized to issue a total of Thirty
          Million (30,000,000) shares of capital stock which shall be subdivided
          into classes as follows:


               (a) Twenty-five Million  (25,000,000) shares of the Corporation's
          capital stock shall be denominated  as Common Stock,  have a par value
          of $.004 per share,  and have the rights,  powers and  preferences set
          forth in this  paragraph.  The  Holders of Common  Stock  shall  share
          ratably,  with all other  classes of common  equity,  in any dividends
          that may, from time to time, be declared by the Board of Directors. No
          dividends  may be paid with  respect to  Corporation's  Common  Stock,
          however,  until  dividend  distributions  to the holders of  Preferred
          Stock,  if any, have been paid in accordance  with the  certificate or
          certificates  of  designation  relating to such Preferred  Stock.  The
          holders of Common Stock shall share ratably, with all other classes of
          common equity, in any assets of the Corporation that are available for
          distribution  to  the  holders  of  common  equity  securities  of the
          Corporation  upon the  dissolution or liquidation of the  Corporation.
          The  holders of Common  Stock  shall be  entitled to cast one vote per
          share  on  all  matters  that  are   submitted   for  a  vote  of  the
          stockholders. Effective at 5:00 p.m. EST on April 2, 1999, and without
          any further action by the holders the Common Stock of the Corporation,
          the NINE  MILLION,  ONE  HUNDRED  SEVENTY-SIX  THOUSAND  FIVE  HUNDRED
          FIFTY-FOUR   (9,176,554)   issued  and   outstanding   shares  of  the
          Corporation's Common Stock shall be consolidated or "reverse split" in
          the  ratio of one (1) new  share  for  every  thirty  and  5885/10,000
          (30.5885) shares currently held by a stockholder. No fractional shares
          shall  be  issued  in  connection  with  the  reverse  split  and  all
          calculations  that would result in the issuance of a fractional  share
          shall be rounded up to the nearest whole number.


               (b)  Five  Million   (5,000,000)   shares  of  the  Corporation's
          authorized  capital stock shall be denominated as Preferred Stock, par
          value of $.004 per share. Shares of Preferred Stock may be issued from
          time to time in one or more  series  as the  Board  of  Directors,  by
          resolution or resolutions,  may from time to time  determine,  each of
          said  series  to  be  distinctively  designated.  The  voting  powers,
          preferences  and relative,  participating,  optional and other special
          rights, and the qualifications,  limitations or restrictions  thereof,
          if any, of each such series of  Preferred  Stock may differ from those
          of  any  and  all  other  series  of  Preferred   Stock  at  any  time
          outstanding,  and the Board of Directors is hereby  expressly  granted
          authority  to  fix  or  alter,  by  resolution  or  resolutions,   the
          designation,   number,   voting  powers,   preferences  and  relative,
          participating,   optional   and   other   special   rights,   and  the
          qualifications,  limitations and  restrictions  thereof,  of each such
          series of Preferred Stock.


               BIO-RESPONSE,  Inc.  has caused  this  Corrected  Certificate  of
          Amendment  to be signed  by its  authorized  officer  this 25th day of
          October, 1999.


                                          BIO-RESPONSE, INC.



                                          By:            /s/
                                                  -----------------------
                                          Name:   Sally A. Fonner
                                          Title:  President





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