PRUDENTIAL NATIONAL MUNICIPALS FUND INC
24F-2NT, 1995-02-24
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                                             February 22, 1995


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC 20549

Re:  Rule 24f-2 Notice for Prudential National Municipals
     Fund, Inc.
     Registration Statement on Form N-1A (File No. 2-66407)    

Ladies and Gentlemen:

     This Notice is filed on behalf of Prudential National
Municipals Fund pursuant to the requirements of Rule 24f-2 under
the Investment Company Act of 1940.

     1.   Fiscal year for which notice is filed: 12/31/94.

     2.   Number of shares registered under the Securities Act of
          1933 other than pursuant to Rule 24f-2 but which remained
          unsold as of the beginning of the fiscal year (1/1/94):
          None.

     3.   The number of shares registered during the fiscal year
          ended 12/31/94 other than pursuant to Rule 24f-2:
          2,119,514.

     4.   The number of shares sold* during the fiscal year ended
          12/31/94: 5,634,218

     5.   The number of shares sold during the fiscal year ended
          12/31/94 in reliance upon Rule 24f-2: 5,634,218.

     Pursuant to the requirements of Rule 24f-2, enclosed please
find the required opinion of counsel.  

*Calculation of Fee           No. of Shares        Dollar Amount

Shares sold                    5,634,218            $84,356,509  
Shares redeemed              (13,326,601)          ($200,260,890)
Net of sales for calculation
     of fee                   (7,692,383)          ($115,904,381)
                                                                 
Fee at 1/29 of 1%                                   $    -0-     

                                             Very truly yours,

                                             /s/ S. Jane Rose
                                             S. Jane Rose
                                             Secretary
SJR/ln
Enclosure





SULLIVAN & CROMWELL

NEW YORK TELEPHONE: (212) 558-4000
TELEX: 62694 (INTERNATIONAL) 127816 (DOMESTIC)
125 Broad Street, New York 10004-2498
CABLE ADDRESS: LADYCOURT, NEW YORK                     __________
FACSIMILE: (212) 558-3588 (125 Broad Street)
250 PARK AVENUE, NEW YORK 10177-0021
     (212) 558-3792 (250 Park Avenue)
1701 PENNSYLVANIA AVE, N.W. WASHINGTON, D.C. 20006-5805
444 SOUTH FLOWER STREET, LOS ANGELES 90071-2901
8, PLACE VEND-ME, 75001 PARIS
ST. OLAVE'S HOUSE, 9a IRONMONGER LANE, LONDON EC2V 8EY
101 COLLINS STREET, MELBOURNE 3000
2-1, MARUNOUCHI I-CHOME, CHIYODA-KU, TOKYO 100
GLOUCESTER TOWER, 11 PEDDER STREET, HONG KONG
                                        February 24, 1995



Prudential National Municipals Fund, Inc.,
   One Seaport Plaza,
      New York, New York  10292.

Dear Sirs:

          You have requested our opinion in connection with the notice which you
propose to file pursuant to Rule 24f-2 under the Investment Company Act of 1940
with respect to  5,634,218 shares of your Common Stock, $.01 par value (the
"Shares").
          As your counsel, we are familiar with your organization and corporate
status and the validity of your Common Stock.
          We advise you that, in our opinion, the Shares are legally and validly
issued, fully paid and nonassessable.
          The foregoing opinion is limited to the Federal laws of the United
States and the General Corporation Laws of the State of Maryland, and we are
expressing no opinion as to the effect of the laws of any other jurisdiction.
          We consent to the filing of this opinion with the Securities and
Exchange Commission in connection with the notice referred to above.  In giving
such consent, we do not thereby admit that we come within the category of
persons whose consent is required under Section 7 of the Securities Act of 1933.


                                   Very truly yours,

                                   /s/Sullivan & Cromwell
                                   SULLIVAN & CROMWELL


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