<PAGE> PAGE 1
000 B000000 12/31/99
000 C000000 0000314612
000 D000000 N
000 E000000 NC
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 3.0.a
000 J000000 U
001 A000000 PRUDENTIAL NATIONAL MUNICIPALS FUND, INC.
001 B000000 811-2992
001 C000000 9733677530
002 A000000 100 MULBERRY STREET
002 B000000 NEWARK
002 C000000 NJ
002 D010000 07102
002 D020000 4077
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
007 C010100 1
007 C010200 2
007 C010300 3
007 C010400 4
007 C010500 5
007 C010600 6
007 C010700 7
007 C010800 8
007 C010900 9
007 C011000 10
008 A000001 PRUDENTIAL INVESTMENTS FUND MANAGEMENT LLC
008 B000001 A
008 C000001 801-31104
008 D010001 NEWARK
008 D020001 NJ
008 D030001 07102
008 D040001 4077
008 A000002 THE PRUDENTIAL INVESTMENT CORPORATION
008 B000002 S
008 C000002 801-22808
008 D010002 NEWARK
008 D020002 NJ
008 D030002 07102
008 D040002 3777
011 A000001 PRUDENTIAL SECURITIES INCORPORATED
011 B000001 8-27154
011 C010001 NEW YORK
011 C020001 NY
<PAGE> PAGE 2
011 C030001 10292
012 A000001 PRUDENTIAL MUTUAL FUND SERVICES LLC.
012 B000001 85-4110019
012 C010001 NEW BRUNSWICK
012 C020001 NJ
012 C030001 08906
013 A000001 PRICEWATERHOUSECOOPERS LLP
013 B010001 NEW YORK
013 B020001 NY
013 B030001 10036
014 A000001 PRUDENTIAL SECURITIES INCORPORATED
014 B000001 8-27154
014 A000002 PRUCO SECURITIES CORPORATION
014 B000002 8-16402
014 A000003 PRUDENTIAL INVESTMENT MANAGEMENT SERVICES LLC
014 B000003 8-36540
015 A000001 STATE STREET BANK & TRUST CO.
015 B000001 C
015 C010001 NORTH QUINCY
015 C020001 MA
015 C030001 02205
015 E010001 X
018 000000 Y
019 A000000 Y
019 B000000 115
019 C000000 PRUDENTIAL
020 A000001 BEAR, STEARNS & CO., INC.
020 B000001 13-3299429
020 C000001 40
020 A000002 MERRILL LYNCH, PIERCE, FENNER & SMITH, INC.
020 B000002 13-5674085
020 C000002 5
020 C000003 0
020 C000004 0
020 C000005 0
020 C000006 0
020 C000007 0
020 C000008 0
020 C000009 0
020 C000010 0
021 000000 45
022 A000001 GOLDMAN, SACHS & CO.
022 B000001 13-5108880
022 C000001 113229
022 D000001 109416
022 A000002 BEAR, STEARNS & CO., INC.
022 B000002 13-3299429
022 C000002 31203
022 D000002 24520
022 A000003 SALOMON SMITH BARNEY, INC.
022 B000003 13-3082694
<PAGE> PAGE 3
022 C000003 17490
022 D000003 26327
022 A000004 MORGAN (J.P.) SECURITIES, INC.
022 B000004 13-3224016
022 C000004 22000
022 D000004 14200
022 A000005 FLEET SECURITIES, INC.
022 B000005 13-3217611
022 C000005 9450
022 D000005 16125
022 A000006 MAXCOR FINANCIAL GROUP
022 B000006 N\A
022 C000006 9777
022 D000006 11858
022 A000007 LEHMAN BROTHERS, INC.
022 B000007 13-2518466
022 C000007 9819
022 D000007 9838
022 A000008 PAINEWEBBWER, INC.
022 B000008 13-2638166
022 C000008 10223
022 D000008 9226
022 A000009 MORGAN STANLEY DEAN WITTER & CO., INC.
022 B000009 13-2655998
022 C000009 11116
022 D000009 6116
022 A000010 MERRILL LYNCH, PIERCE, FENNER & SMITH, INC.
022 B000010 13-5674085
022 C000010 4133
022 D000010 12868
023 C000000 288502
023 D000000 362435
024 000000 N
025 D000001 0
025 D000002 0
025 D000003 0
025 D000004 0
025 D000005 0
025 D000006 0
025 D000007 0
025 D000008 0
026 A000000 N
026 B000000 N
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027 000000 Y
<PAGE> PAGE 4
028 A010000 11285
028 A020000 1492
028 A030000 0
028 A040000 21567
028 B010000 14133
028 B020000 1646
028 B030000 0
028 B040000 17827
028 C010000 20795
028 C020000 1692
028 C030000 0
028 C040000 25519
028 D010000 6770
028 D020000 1466
028 D030000 0
028 D040000 12585
028 E010000 7434
028 E020000 1606
028 E030000 0
028 E040000 23704
028 F010000 17584
028 F020000 1611
028 F030000 0
028 F040000 22710
028 G010000 78001
028 G020000 9513
028 G030000 0
028 G040000 123912
028 H000000 69438
029 000000 Y
030 A000000 74
030 B000000 3.00
030 C000000 0.00
031 A000000 1
031 B000000 0
032 000000 0
033 000000 73
034 000000 Y
035 000000 144
036 A000000 N
036 B000000 0
037 000000 N
038 000000 0
039 000000 N
040 000000 Y
041 000000 Y
042 A000000 0
042 B000000 0
042 C000000 0
042 D000000 100
042 E000000 0
<PAGE> PAGE 5
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 1939
044 000000 0
045 000000 Y
046 000000 N
047 000000 Y
048 000000 0.000
048 A010000 250000
048 A020000 0.500
048 B010000 250000
048 B020000 0.475
048 C010000 500000
048 C020000 0.450
048 D010000 250000
048 D020000 0.425
048 E010000 250000
048 E020000 0.400
048 F010000 0
048 F020000 0.000
048 G010000 0
048 G020000 0.000
048 H010000 0
048 H020000 0.000
048 I010000 0
048 I020000 0.000
048 J010000 0
048 J020000 0.000
048 K010000 1500000
048 K020000 0.375
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 N
054 A000000 Y
054 B000000 Y
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 N
054 N000000 N
054 O000000 N
<PAGE> PAGE 6
055 A000000 Y
055 B000000 N
056 000000 Y
057 000000 N
058 A000000 N
059 000000 Y
060 A000000 Y
060 B000000 Y
061 000000 1000
062 A000000 Y
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 3.5
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 95.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
063 A000000 0
063 B000000 16.9
064 A000000 Y
064 B000000 N
066 A000000 N
067 000000 N
068 A000000 N
068 B000000 N
069 000000 N
070 A010000 N
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 Y
070 E020000 Y
070 F010000 N
070 F020000 N
070 G010000 Y
070 G020000 Y
070 H010000 N
<PAGE> PAGE 7
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 N
070 K020000 N
070 L010000 N
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 N
070 N020000 N
070 O010000 Y
070 O020000 Y
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000 217301
071 B000000 196204
071 C000000 663985
071 D000000 30
072 A000000 12
072 B000000 37521
072 C000000 0
072 D000000 0
072 E000000 0
072 F000000 3129
072 G000000 0
072 H000000 0
072 I000000 380
072 J000000 150
072 K000000 0
072 L000000 150
072 M000000 40
072 N000000 47
072 O000000 0
072 P000000 0
072 Q000000 0
072 R000000 39
072 S000000 45
072 T000000 1940
072 U000000 0
072 V000000 0
072 W000000 8
072 X000000 5928
072 Y000000 8
072 Z000000 31601
<PAGE> PAGE 8
072AA000000 7482
072BB000000 7856
072CC010000 0
072CC020000 47340
072DD010000 5476
072DD020000 26246
072EE000000 0
073 A010000 0.0000
073 A020000 0.0000
073 B000000 0.0000
073 C000000 0.0000
074 A000000 94
074 B000000 0
074 C000000 20800
074 D000000 565066
074 E000000 0
074 F000000 0
074 G000000 0
074 H000000 25
074 I000000 0
074 J000000 478
074 K000000 0
074 L000000 10846
074 M000000 18
074 N000000 597327
074 O000000 0
074 P000000 394
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 0
074 R040000 2383
074 S000000 0
074 T000000 594550
074 U010000 6254
074 U020000 34127
074 V010000 0.00
074 V020000 0.00
074 W000000 0.0000
074 X000000 26208
074 Y000000 0
075 A000000 0
075 B000000 654681
076 000000 0.00
077 A000000 Y
077 B000000 Y
077 C000000 N
077 D000000 N
077 E000000 N
077 F000000 N
077 G000000 N
<PAGE> PAGE 9
077 H000000 N
077 I000000 N
077 J000000 Y
077 K000000 N
077 L000000 N
077 M000000 Y
077 N000000 N
077 O000000 Y
077 P000000 N
077 Q010000 N
077 Q020000 N
077 Q030000 N
078 000000 N
080 A000000 ICI MUTUAL INSURANCE COMPANY
080 C000000 70000
081 A000000 Y
081 B000000 86
082 A000000 N
082 B000000 0
083 A000000 N
083 B000000 0
084 A000000 N
084 B000000 0
085 A000000 Y
085 B000000 N
086 A010000 0
086 A020000 0
086 B010000 0
086 B020000 0
086 C010000 0
086 C020000 0
086 D010000 0
086 D020000 0
086 E010000 0
086 E020000 0
086 F010000 0
086 F020000 0
SIGNATURE GRACE TORRES
TITLE TREASURER
For the fiscal year ended (a) 12/31/99
File number (c) 811-2992
SUB-ITEM 77 0
EXHIBITS
Transactions Effected Pursuant to Rule 10f-3
1. Name of Issuer
City of Chicago General Obligation
Bonds
2. Date of Purchase
11/09/99
3. Number of Securities Purchased
100,000
4. Dollar Amount of Purchase
$2,166,900
5. Price Per Unit
$21.669
6. Name(s) of Underwriter(s) or Dealer(s)
From whom Purchased
Goldman Sachs
7. Other Members of the Underwriting
Syndicate
Morgan Stanley Dean Witter
Siebert Brandford Shank & Co., LLC
M.R. Beal & Company
Banc of America Securities
Bear, Stearns & Co., Inc.
LaSalle Capital Markets
Podest & Co.
Banc One Capital Markets, Inc.
Berean Capital, Inc.
Loop Capital Markets, LLC
Ramirez & Co., Inc.
Dain Rauscher Incorporated
Melvin Securities LLC
For the fiscal year ended (a) 12/31/99
File number (c) 811-2992
SUB-ITEM 77 0
EXHIBITS
Transactions Effected Pursuant to Rule 10f-3
1. Name of Issuer
City of Chicago General Obligation
Bonds
2. Date of Purchase
11/09/99
3. Number of Securities Purchased
50,000
4. Dollar Amount of Purchase
$1,154,250
5. Price Per Unit
$23.085
6. Name(s) of Underwriter(s) or Dealer(s)
From whom Purchased
Goldman Sachs
7. Other Members of the Underwriting
Syndicate
Morgan Stanley Dean Witter
Siebert Brandford Shank & Co., LLC
M.R. Beal & Company
Banc of America Securities
Bear, Stearns & Co., Inc.
LaSalle Capital Markets
Podest & Co.
Banc One Capital Markets, Inc.
Berean Capital, Inc.
Loop Capital Markets, LLC
Ramirez & Co., Inc.
Dain Rauscher Incorporated
Melvin Securities LLC
For the fiscal year ended (a) 12/31/99
File number (c) 811-2992
SUB-ITEM 77 0
EXHIBITS
Transactions Effected Pursuant to Rule 10f-3
1. Name of Issuer
Metropolitan Transportation Authority,
NY
2. Date of Purchase
10/27/99
For the year ended December 31, 1999
File number 811-2992
SUB-ITEM 77J
Reclassification of Capital Accounts
The Fund accounts and reports for
distributions to shareholders in accordance
with the American Institute of Certified
Public Accountants', Statement of Position 93-
2: Determination, Disclosure, and Financial
Statement Presentation of Income, Capital
Gain, and Return of Capital Distributions by
Investment Companies. The effect of applying
this statement was to increase undistributed
net investment income by $120,704, increase
accumulated net realized loss on investments
by $149,567 and increase paid in capital by
$28,863, due to the sale of securities
purchased with market discount during the year
ended December 31, 1999. Net investment
income, net realized gains and net assets were
not affected by this change.
For the fiscal period ended (a) 6/30/99
File number (c) 811-2992
SUB-ITEM 77M
Mergers
On January 22, 1999, Prudential National
Municipals Fund, Inc. (The Registrant),
acquired all the net assets of Prudential
Municipal Series Fund (Maryland and Michigan
Series) and Prudential Municipal Bond Fund
(Intermediate Series) pursuant to a plan of
reorganization approved by Prudential
Municipal Series Fund (Maryland and Michigan
Series) and Prudential Municipal Bond Fund
(Intermediate Series) shareholders on January
14, 1999. The reorganization was approved by
the Directors of the Registrant on August 26,
1998 but did not require the approval of the
Registrant's shareholders. The acquisition
was accomplished on January 22, 1999, by a tax-
free exchange of Class A, Class B, Class C and
Class Z shares of Prudential National
Municipals Fund, Inc. for the net assets of
Prudential Municipal Series Fund (Maryland and
Michigan Series) and Prudential Municipal Bond
Fund (Intermediate Series).
To the Shareholders and Board of Directors of
Prudential National Municipals Fund, Inc.
(2)
Report of Independent Accountants
To the Shareholders and Board of Directors of
Prudential National Municipals Fund, Inc.
In planning and performing our audit of the
financial statements of Prudential National
Municipals Fund, Inc., (the "Fund") for the year
ended December 31, 1999, we considered its
internal control, including control activities
for safeguarding securities, in order to
determine our auditing procedures for the
purpose of expressing our opinion on the
financial statements and to comply with the
requirements of Form N-SAR, not to provide
assurance on internal control.
The management of the Fund is responsible for
establishing and maintaining internal control.
In fulfilling this responsibility, estimates and
judgments by management are required to assess
the expected benefits and related costs of
controls. Generally, controls that are relevant
to an audit pertain to the entity's objective of
preparing financial statements for external
purposes that are fairly presented in conformity
with generally accepted accounting principles.
Those controls include the safeguarding of
assets against unauthorized acquisition, use or
disposition.
Because of inherent limitations in internal
control, errors or fraud may occur and not be
detected. Also, projection of any evaluation of
internal control to future periods is subject to
the risk that controls may become inadequate
because of changes in conditions or that the
effectiveness of the design and operation may
deteriorate.
Our consideration of internal control would not
necessarily disclose all matters in internal
control that might be material weaknesses under
standards established by the American Institute
of Certified Public Accountants. A material
weakness is a condition in which the design or
operation of one or more of the internal control
components does not reduce to a relatively low
level the risk that misstatements caused by
error or fraud in amounts that would be material
in relation to the financial statements being
audited may occur and not be detected within a
timely period by employees in the normal course
of performing their assigned functions.
However, we noted no matters involving internal
control and its operation, including controls
for safeguarding securities, that we consider to
be material weaknesses as defined above as of
December 31, 1999.
This report is intended solely for the
information and use of the Board of Directors,
management and the Securities and Exchange
Commission and is not intended to be and should
not be used by anyone other than these specified
parties.
PricewaterhouseCoopers LLP
February 18, 2000
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000314612
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC.
<SERIES>
<NUMBER> 001
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC. (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> DEC-31-1999
<PERIOD-END> DEC-31-1999
<INVESTMENTS-AT-COST> 582,815,428
<INVESTMENTS-AT-VALUE> 585,890,853
<RECEIVABLES> 11,323,757
<ASSETS-OTHER> 112,213
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 597,326,823
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 2,776,766
<TOTAL-LIABILITIES> 2,776,766
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 592,667,426
<SHARES-COMMON-STOCK> 40,380,881
<SHARES-COMMON-PRIOR> 37,587,023
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (1,252,169)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,134,800
<NET-ASSETS> 594,550,057
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 37,520,953
<OTHER-INCOME> 0
<EXPENSES-NET> 5,919,825
<NET-INVESTMENT-INCOME> 31,601,128
<REALIZED-GAINS-CURRENT> (373,416)
<APPREC-INCREASE-CURRENT> (47,339,939)
<NET-CHANGE-FROM-OPS> (16,112,227)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (16,112,227)
<DISTRIBUTIONS-OF-GAINS> (31,601,128)
<DISTRIBUTIONS-OTHER> (120,704)
<NUMBER-OF-SHARES-SOLD> 280,554,937
<NUMBER-OF-SHARES-REDEEMED> (261,665,210)
<SHARES-REINVESTED> 19,573,958
<NET-CHANGE-IN-ASSETS> (25,482,601)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,183,274
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3,129,064
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 5,912,114
<AVERAGE-NET-ASSETS> 531,603,000
<PER-SHARE-NAV-BEGIN> 16.06
<PER-SHARE-NII> 0.76
<PER-SHARE-GAIN-APPREC> (1.34)
<PER-SHARE-DIVIDEND> (0.76)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 14.72
<EXPENSE-RATIO> 0.86
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000314612
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC.
<SERIES>
<NUMBER> 002
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC. (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> DEC-31-1999
<PERIOD-END> DEC-31-1999
<INVESTMENTS-AT-COST> 582,815,428
<INVESTMENTS-AT-VALUE> 585,890,853
<RECEIVABLES> 11,323,757
<ASSETS-OTHER> 112,213
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 597,326,823
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 2,776,766
<TOTAL-LIABILITIES> 2,776,766
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 592,667,426
<SHARES-COMMON-STOCK> 40,380,881
<SHARES-COMMON-PRIOR> 37,587,023
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (1,252,169)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,134,800
<NET-ASSETS> 594,550,057
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 37,520,953
<OTHER-INCOME> 0
<EXPENSES-NET> 5,919,825
<NET-INVESTMENT-INCOME> 31,601,128
<REALIZED-GAINS-CURRENT> (373,416)
<APPREC-INCREASE-CURRENT> (47,339,939)
<NET-CHANGE-FROM-OPS> (16,112,227)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (16,112,227)
<DISTRIBUTIONS-OF-GAINS> (31,601,128)
<DISTRIBUTIONS-OTHER> (120,704)
<NUMBER-OF-SHARES-SOLD> 280,554,937
<NUMBER-OF-SHARES-REDEEMED> (261,665,210)
<SHARES-REINVESTED> 19,573,958
<NET-CHANGE-IN-ASSETS> (25,482,601)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,183,274
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3,129,064
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 5,912,114
<AVERAGE-NET-ASSETS> 118,044,000
<PER-SHARE-NAV-BEGIN> 16.10
<PER-SHARE-NII> 0.73
<PER-SHARE-GAIN-APPREC> (1.35)
<PER-SHARE-DIVIDEND> (0.73)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 14.75
<EXPENSE-RATIO> 1.11
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000314612
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC.
<SERIES>
<NUMBER> 003
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC. (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> DEC-31-1999
<PERIOD-END> DEC-31-1999
<INVESTMENTS-AT-COST> 582,815,428
<INVESTMENTS-AT-VALUE> 585,890,853
<RECEIVABLES> 11,323,757
<ASSETS-OTHER> 112,213
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 597,326,823
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 2,776,766
<TOTAL-LIABILITIES> 2,776,766
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 592,667,426
<SHARES-COMMON-STOCK> 40,380,881
<SHARES-COMMON-PRIOR> 37,587,023
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (1,252,169)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,134,800
<NET-ASSETS> 594,550,057
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 37,520,953
<OTHER-INCOME> 0
<EXPENSES-NET> 5,919,825
<NET-INVESTMENT-INCOME> 31,601,128
<REALIZED-GAINS-CURRENT> (373,416)
<APPREC-INCREASE-CURRENT> (47,339,939)
<NET-CHANGE-FROM-OPS> (16,112,227)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (16,112,227)
<DISTRIBUTIONS-OF-GAINS> (31,601,128)
<DISTRIBUTIONS-OTHER> (120,704)
<NUMBER-OF-SHARES-SOLD> 280,554,937
<NUMBER-OF-SHARES-REDEEMED> (261,665,210)
<SHARES-REINVESTED> 19,573,958
<NET-CHANGE-IN-ASSETS> (25,482,601)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,183,274
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3,129,064
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 5,912,114
<AVERAGE-NET-ASSETS> 2,643,000
<PER-SHARE-NAV-BEGIN> 16.10
<PER-SHARE-NII> 0.69
<PER-SHARE-GAIN-APPREC> (1.35)
<PER-SHARE-DIVIDEND> (0.69)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 14.75
<EXPENSE-RATIO> 1.36
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000314612
<NAME> PRUDENTIAL NATIONAL MUNICIPALS FUND, INC.
<SERIES>
<NUMBER> 004
<NAME> #
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> DEC-31-1999
<PERIOD-END> DEC-31-1999
<INVESTMENTS-AT-COST> 582,815,428
<INVESTMENTS-AT-VALUE> 585,890,853
<RECEIVABLES> 11,323,757
<ASSETS-OTHER> 112,213
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 597,326,823
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 2,776,766
<TOTAL-LIABILITIES> 2,776,766
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 592,667,426
<SHARES-COMMON-STOCK> 40,380,881
<SHARES-COMMON-PRIOR> 37,587,023
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (1,252,169)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,134,800
<NET-ASSETS> 594,550,057
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 37,520,953
<OTHER-INCOME> 0
<EXPENSES-NET> 5,919,825
<NET-INVESTMENT-INCOME> 31,601,128
<REALIZED-GAINS-CURRENT> (373,416)
<APPREC-INCREASE-CURRENT> (47,339,939)
<NET-CHANGE-FROM-OPS> (16,112,227)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (16,112,227)
<DISTRIBUTIONS-OF-GAINS> (31,601,128)
<DISTRIBUTIONS-OTHER> (120,704)
<NUMBER-OF-SHARES-SOLD> 280,554,937
<NUMBER-OF-SHARES-REDEEMED> (261,665,210)
<SHARES-REINVESTED> 19,573,958
<NET-CHANGE-IN-ASSETS> (25,482,601)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,183,274
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3,129,064
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 5,912,114
<AVERAGE-NET-ASSETS> 1,391,000
<PER-SHARE-NAV-BEGIN> 16
<PER-SHARE-NII> 1
<PER-SHARE-GAIN-APPREC> (1)
<PER-SHARE-DIVIDEND> (1)
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 15
<EXPENSE-RATIO> 1
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
</TABLE>
