FMR CORP
SC 13G/A, 1994-04-07
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SCHEDULE 13G

Amendment No. 4
Chiron Corporation
common stock
Cusip # 170040109
Filing Fee: No


Cusip # 170040109
Item 1:	Reporting Person - FMR Corp. - (Tax ID:  04-2507163)
Item 4:	Commonwealth of Massachusetts
Item 5:	14,491
Item 6:	None
Item 7:	248,951
Item 8:	None
Item 9:	248,951
Item 11:	0.77%
Item 12:	HC 




Cusip # 170040109
Item 1:	Reporting Person - Edward C. Johnson 3d - (Tax ID:  ###-##-####)
Item 4:	United States of America
Item 5:	None
Item 6:	None
Item 7:	248,951
Item 8:	None
Item 9:	248,951
Item 11:	0.77%
Item 12:	IN 




SCHEDULE 13G - TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULE 13d-1(b) or 13d-2(b)


Item 1(a).	Name of Issuer:

		Chiron Corporation

Item 1(b).	Name of Issuer's Principal Executive Offices:

		4560 Horton Street
		Emeryville, CA  94608

Item 2(a).	Name of Person Filing: 

		FMR Corp.

Item 2(b).	Address or Principal Business Office or, if None, Residence:

		82 Devonshire Street, Boston, Massachusetts  02109

Item 2(c).	Citizenship:

		Not applicable

Item 2(d).	Title of Class of Securities:

		Common Stock

Item 2(e).	CUSIP Number:  

		170040109

Item 3.	This statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) and the 
person filing, FMR Corp., is a parent holding company in accordance 
with Section 240.13d-1(b)(ii)(G).  (Note:  See Item 7).

Item 4.	Ownership

	(a)	Amount Beneficially Owned:
	248,951

	(b)	Percent of Class:
	0.77%

	(c)	Number of shares as to which such person has:  

	(i)	sole power to vote or to direct the vote:
	14,491

	(ii)	shared power to vote or to direct the vote:
	None

	(iii)	sole power to dispose or to direct the disposition of:
	248,951

	(iv)	shared power to dispose or to direct the disposition 
of:	None




Item 5.	Ownership of Five Percent or Less of a Class.

	If this statement is being filed to report the fact that as 
of the date hereof, the reporting person has ceased to be 
the beneficial owner of more than five percent of the class 
of securities, check the following (X).

Item 6.	Ownership of More than Five Percent on Behalf of Another Person.

	Not applicable.

Item 7.	Identification and Classification of the Subsidiary Which Acquired 
the Security Being Reported on By the Parent Holding Company.

	See attached Exhibit(s) A, B, and C.

Item 8.	Identification and Classification of Members of the Group.

	Not applicable, see attached Exhibit A. 

Item 9.	Notice of Dissolution of Group.

	Not applicable.


Item 10.	Certification.

	Inasmuch as the reporting persons are no longer the beneficial 
owners of more than 5% of the number of shares outstanding, the 
reporting persons have no further reporting obligation under 
section 13(d) of the Securities and Exchange Commission 
thereunder, and the reporting persons have no obligation to amend 
this Statement if any material change occurs in the facts set 
forth herein.


Signature

	After reasonable inquiry and to the best of my knowledge and 
belief, I certify that the information set forth in this statement 
is true, complete and correct. 



	April 8, 1994	
Date



	/s/Arthur S. Loring
Signature



	Arthur S. Loring, Vice President
	
Name/Title




SCHEDULE 13G - TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULE 13d-1(b) or 13d-2(b)

	Pursuant to the instructions in Item 7 of Schedule 13G, Fidelity 
Management & Research Company ("Fidelity"), 82 Devonshire Street, Boston, 
Massachusetts 02109, a wholly-owned subsidiary of FMR Corp. and an 
investment adviser registered under Section 203 of the Investment Advisers 
Act of 1940, is the beneficial owner of 234,460 shares or 0.73% of the 
common stock outstanding of Chiron Corporation ("the Company") as a result 
of acting as investment adviser to several investment companies registered 
under Section 8 of the Investment Company Act of 1940.  The number of 
shares of common stock of Chiron Corporation owned by the investment 
companies at March 31, 1994 included 9,945 shares of common stock resulting 
from the assumed conversion of $1,150,000 principal amount of 1.9% 
Convertible Subordinated Debentures (8.6481 shares of common stock for each 
$1,000 principal amount of debenture).

	Edward C. Johnson 3d, FMR Corp., through its control of Fidelity, and 
the Funds each has sole power to dispose of the 234,460 shares owned by the 
Funds.

	Neither FMR Corp. nor Edward C. Johnson 3d, Chairman of FMR Corp., has 
the sole power to vote or direct the voting of the shares owned directly by 
the Fidelity Funds, which power resides with the Funds' Boards of Trustees.  
Fidelity carries out the voting of the shares under written guidelines 
established by the Funds' Boards of Trustees.

	Fidelity Management Trust Company, 82 Devonshire Street, Boston, 
Massachusetts 02109, a wholly-owned subsidiary of FMR Corp. and a bank as 
defined in Section 3(a)(6) of the Securities Exchange Act of 1934, is the 
beneficial owner of 9,900 shares or 0.03% of the common stock outstanding 
of the company as a result of its serving as investment manager of the 
institutional account(s).  

	FMR Corp., through its control of Fidelity Management Trust Company, 
has sole voting and dispositive power over 9,900 shares of common stock 
owned by the institutional account(s) as reported above.

	Edward C. Johnson 3d owns 34.0% of the outstanding voting common stock 
of FMR Corp.  Mr. Johnson 3d is Chairman of FMR Corp.  Various Johnson 
family members and trusts for the benefit of Johnson family members own FMR 
Corp. voting common stock.  These Johnson family members, through their 
ownership of voting common stock, form a controlling group with respect to 
FMR Corp.

	Fidelity International Limited, Pembroke Hall, 42 Crowlane, Hamilton, 
Bermuda, and various foreign-based subsidiaries provide investment advisory 
and management services to a number of non-U.S. investment companies (the 
"International Funds") and certain institutional investors.  Fidelity 
International Limited is the beneficial owner of 4,591 shares or 0.01% of 
the common stock outstanding of the company.  Additional information with 
respect to the beneficial ownership of Fidelity International Limited is 
shown on Exhibit B, page 1.


SCHEDULE 13G - TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULE 13d-1(b) or 13d-2(b)


	Pursuant to instructions in Item 7 of Schedule 13G, this Exhibit has 
been prepared  to identify Fidelity International Limited, Pembroke Hall, 
42 Crow Lane, Hamilton, Bermuda, a Bermudian joint stock company 
incorporated for an unlimited duration by private act of the Bermuda 
Legislature (FIL) and an investment adviser to various investment companies 
(the "International Funds") and certain institutional investors, as a 
beneficial owner of the 4,591 shares or 0.01% of the common stock 
outstanding of Chiron Corporation.

	Prior to June 30, 1980, FIL was a majority-owned subsidiary of 
Fidelity Management & Research Company (Fidelity), a wholly-owned 
subsidiary of FMR Corp.  On that date, the shares of FIL held by Fidelity 
were distributed, as a dividend,  to the shareholders of FMR Corp.  FIL 
currently operates as an entity independent of FMR Corp. and Fidelity.  The 
International Funds and FIL's other clients, with the exception of Fidelity 
and an affiliated company of Fidelity, are non-U.S. entities.

	A partnership controlled by Edward C. Johnson 3d and members of his 
family owns shares of FIL voting stock with the right to cast approximately 
48.879% of the total votes which may be cast by all holders of FIL voting 
stock.  Mr. Johnson 3d is Chairman of FMR Corp. and FIL.  FMR Corp. and FIL 
are separate and independent corporate entities.  FMR Corp. and FIL are 
managed independently and their Boards of Directors are generally composed 
of different individuals.  Their investment decisions are made 
independently, and their clients are different organizations.

	FMR Corp. and FIL are of the view that they are not acting as a 
"group" for purposes of Section 13(d) under the Securities Exchange Act of 
1934 (the "1934" Act) and that they are not otherwise required to attribute 
to each other the "beneficial ownership" of securities "beneficially owned" 
by the other corporation within the meaning of Rule 13d-3 promulgated under 
the 1934 Act.  Therefore, they are of the view that the shares held by the 
other corporation need not be aggregated for purposes of Section 13(d). 
However, FMR Corp. is making this filing on a voluntary basis as if all of 
the shares are beneficially owned by FMR Corp. and FIL on a joint basis.

	FIL may continue to have the International Funds or other accounts 
purchase shares subject to a number of factors, including, among others, 
the availability of shares for sale at what FIL considers to be reasonable 
prices and other investment opportunities that may be available to the 
International Funds.

	FIL intends to review continuously the equity position of the 
International Funds and other accounts in the Company.  Depending upon its 
future evaluations of the business and prospects of the Company and upon 
other developments, including, but not limited to, general economic and 
business conditions and money market and stock market conditions, FIL may 
determine to cease making additional purchases of shares or to increase or 
decrease the equity interest in the Company by acquiring additional shares, 
or by disposing of all or a portion of the shares.

	FIL does not have a present plan or proposal which relates to or would 
result in (i) an extraordinary corporate transaction, such as a merger, 
reorganization, liquidation, or sale or transfer of a material amount of 
assets involving the Company or any of its subsidiaries, (ii) any change in 
the Company's present Board of Directors or management, (iii) any material 
changes in the Company's present capitalization or dividend policy or any 
other material change in the Company's business or corporate structure, 
(iv) any change in the Company's charter or by-laws, or (v) the Company's 
common stock becoming eligible for termination of its registration pursuant 
to Section 12(g)(4) of the 1934 Act.

	FIL has the sole power to vote and the sole power to dispose of 4,591 
shares.  


SCHEDULE 13G - TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULE 13d-1(b) or 13d-2(b)

RULE 13d-1(e)  AGREEMENT

	The undersigned persons, on April 8, 1994, agree and consent to the 
joint filing on their behalf of this Schedule 13G in connection with their 
beneficial ownership of the common stock of Chiron Corporation at March 31, 
1994.

	FMR Corp.
	By	/s/Arthur S. Loring
Arthur S. Loring
Vice President - Legal
		Edward C. Johnson 3d
	By	/s/Arthur S. Loring
Arthur S. Loring
Under Power of Attorney 
dated 5/17/89
On File with Schedule 13G 
for
Airborne Freight Corp. 
9/10/91
	Fidelity Management & Research Company
	By	/s/Arthur S. Loring
Arthur S. Loring
Sr. V.P. and General 
Counsel



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