ENZO BIOCHEM INC
SC 13D/A, 2000-02-24
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934

                          (Amendment No. 8)
                          --------------------



                               Enzo Biochem, Inc.
              -----------------------------------------------------
                                (Name of Issuer)

                          Common Stock, $.01 par value
            --------------------------------------------------------
                         (Title of Class of Securities)

                                  294100102
           ----------------------------------------------------------
                                 (CUSIP Number)

                David Selengut, Ellenoff Grossman Schole & Cyrulli, LLP
               370 Lexington Avenue, New York, NY  10017  (212) 370-1300
         ------------------------------------------------------------
                  (Name, Address and Telephone Number of Person
                 Authorized to Receive Notices and Communications)

                             February 18, 2000
          -----------------------------------------------------------
            (Date of Event which Requires FIling of this Statement)


If the filing  person has  previously  filed a statement on Schedule 13G to
report the acquisition  which is the subject of this Schedule 13D, and is filing
this schedule because of Rule 13d-1(e) (f) or (g), check the following box [ ].


*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



                             Page 1 of 5 pages



<PAGE>

CUSIP No.  294100102                 13D                   Page 2 of 5 Pages



- --------------------------------------------------------------------------------
   1   NAME OF REPORTING PERSON
       S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

       J. Morton Davis


- --------------------------------------------------------------------------------
   2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                             (a)  [  ]
                                                             (b)  [  ]


- --------------------------------------------------------------------------------
   3   SEC USE ONLY


- -------------------------------------------------------------------------------
   4   Source of Funds

       See Item #3 herein.

- -------------------------------------------------------------------------------
   5   Check Box if Disclosure of Legal Proceedings is required pursuant to
       Items 2(d) or 2(e)


- -------------------------------------------------------------------------------
   6   CITIZENSHIP OR PLACE OF ORGANIZATION

       United States

- --------------------------------------------------------------------------------
   NUMBER OF      7    SOLE VOTING POWER
     SHARES            1,763,829
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      8    SHARED VOTING POWER
      EACH             0
   REPORTING      --------------------------------------------------------------
     PERSON       9    SOLE DISPOSITIVE POWER
      WITH             1,763,829
                  --------------------------------------------------------------
                  10   SHARED DISPOSITIVE POWER
                       0
- --------------------------------------------------------------------------------
   11  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                       1,948,116
- --------------------------------------------------------------------------------
  12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

                       X
- --------------------------------------------------------------------------------
  13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                       7.8%
- --------------------------------------------------------------------------------
  14   TYPE OF REPORTING PERSON*
                    IN

- --------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT


<PAGE>

CUSIP No.  294100102                 13D           Page 3 of 5 Pages



- --------------------------------------------------------------------------------
   1   NAME OF REPORTING PERSON
       S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

       D.H. Blair Investment Banking Corp.


- --------------------------------------------------------------------------------
   2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                             (a)  [  ]
                                                             (b)  [  ]


- --------------------------------------------------------------------------------
   3   SEC USE ONLY


- -------------------------------------------------------------------------------
   4   Source of Funds

       See Item #3 herein.

- -------------------------------------------------------------------------------
   5   Check Box if Disclosure of Legal Proceedings is required pursuant to
       Items 2(d) or 2(e)


- -------------------------------------------------------------------------------
   6   CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware

- --------------------------------------------------------------------------------
   NUMBER OF      7    SOLE VOTING POWER
     SHARES            0
  BENEFICIALLY    --------------------------------------------------------------
    OWNED BY      8    SHARED VOTING POWER
      EACH             1,230,467
   REPORTING      --------------------------------------------------------------
     PERSON       9    SOLE DISPOSITIVE POWER
      WITH             0
                  --------------------------------------------------------------
                  10   SHARED DISPOSITIVE POWER
                       1,230,467
- --------------------------------------------------------------------------------
   11  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                      1,230,467
- --------------------------------------------------------------------------------
  12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

                      X
- --------------------------------------------------------------------------------
  13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                    4.9%
- --------------------------------------------------------------------------------
  14   TYPE OF REPORTING PERSON*
                    BD

- --------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
                                                            Page 4 of 5 Pages


               J. Morton  Davis and D.H.  Blair  Investment  Banking  Corp.
               ("Blair  Investment"),  (collectively,  the "Reporting  Parties")
               hereby amend the following  items in their  statement on Schedule
               13D relating to the common  stock,  $.01 par value  ("shares") of
               Enzo Biochem, Inc. (the "Issuer") as follows:


Item 3. (a) is hereby amended in its entirety as follows:

          This statement relates to the purchase of 1,000 shares by Mr. Davis
          for $82,000.  Mr. Davis used his personal funds to purchase the
          1,000 shares.

Item 4. is hereby amended in its entirety as follows:

          The purchase of the shares by Mr. Davis was made as an investment in
          the Issuer and not for any reason described in (a) through (j) of
          Item 4.

Item 5. (a) is hereby amended in its entirety as follows:

          As of February 18, 2000, Mr. Davis may be deemed to  beneficially
          own (1)  1,948,116  shares or 7.8% of the Issuer's  shares  issued and
          outstanding  as follows (i) 1,000 shares owned  directly by Mr. Davis,
          (ii)  1,230,467  shares  owned  directly  by Blair  Investment,  (iii)
          532,362  shares owned by Engex,  Inc. (2), (iv) 80,696 shares owned by
          Rosalind Davidowitz,  Mr. Davis' wife, and (v) 103,818 shares owned by
          The Morton Foundation, Inc. (3).

          As of  February  18,  2000,  Blair  Investment  may be  deemed to
          beneficially  own  1,230,467  shares  or 4.9% of the  Issuer's  shares
          issued and outstanding as indicated in (ii) above.

Item 5. (b) is hereby amended in its entirety as follows:

          Mr.  Davis  has sole  power to vote or to  direct  the  vote,  to
          dispose or to direct the  disposition  of those  shares owned by Blair
          Investment. Rosalind Davidowitz has sole power to dispose or to direct
          the  disposition of those shares owned directly by her and those owned
          by  The  Morton  Foundation  (4).  Voting  and  dispositive  decisions
          regarding  shares  owned by Engex are made by Mr. Davis as Chairman of
          the Board.

Item 5 (c) is hereby amended by adding the following paragraphs thereto:

          No transactions were made by the Reporting Parties in the previous
          sixty days.

    __________________________________________________________________________


(1)  Not included  herein are 46,407  shares owned by Kinder  Investments,  L.P.
     ("Kinder") and 10,000 shares owned by Sutton Partners, L.P. ("Sutton"). The
     limited partners of Kinder and Sutton are the children and grandchildren of
     Mr. Davis.  Blair Investment and Mr. Davis disclaim for purposes of Section
     13 or otherwise beneficial ownership of any Enzo Biochem, Inc. shares owned
     by Kinder and Sutton. Kinder and Sutton disclaim for purposes of Section 13
     or otherwise  ownership  of any Enzo  Biochem,  Inc.  shares owned by Blair
     Investment or Mr. Davis.

(2)  Engex, Inc.  ("Engex") is an investment  company registered under Section 8
     of the Investment Company Act. Mr. Davis is reporting as a beneficial owner
     of the securities owned by Engex because of his role as investment  advisor
     to Engex.  Filing of this statement  shall not be deemed an admission by J.
     Morton Davis that he beneficially  owns the securities  attributed to Engex
     for any purpose. J. Morton Davis expressly disclaims  beneficial  ownership
     of all securities held by Engex for any purpose.

(3)  The Morton Foundation,  Inc. is a charitable  corporation controlled by Mr.
     Davis' wife,  Rosalind  Davidowitz.  Filing of this statement  shall not be
     deemed an  admission  by J.  Morton  Davis  that he  beneficially  owns the
     securities attributed to The Morton Foundation,  Inc. or Ms. Davidowitz for
     any purpose.  J. Morton Davis expressly disclaims  beneficial  ownership of
     all securities held by The Morton  Foundation,  Inc. or Ms.  Davidowitz for
     any purpose.



<PAGE>

                                                  Page 5 of 5 pages

                                   SIGNATURES

 After reasonable inquiry and to the best of my knowledge and belief, we
certify that the information set forth in this statement is true, complete
and correct.



                                        /s/ J. Morton Davis
Date:    February 24, 2000              _____________________________
         New York, New York             J. Morton Davis









                                       D.H. BLAIR INVESTMENT BANKING CORP.


                                               /s/ David Nachamie
Date:    February 24, 2000                  by_____________________________
         New York, New York                     David Nachamie
                                                Treasurer









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