<PAGE> PAGE 1
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000 C000000 0000316968
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002 A000000 100 EAST PRATT STREET
002 B000000 BALTIMORE
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022 A000001 GOLDMAN,SACHS & CO
022 B000001 13-5108880
022 C000001 7952899
022 D000001 197893
022 A000002 LEHMAN BROTHERS INC.
022 B000002 13-2518466
022 C000002 4691148
022 D000002 271168
022 A000003 FIRST BOSTON CORPORATION (THE)
022 B000003 13-5659485
022 C000003 3326119
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022 A000004 MERRILL LYNCH, PIERCE, FENNER & SMITH, INC.
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<PAGE> PAGE 2
022 C000004 2356638
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<PAGE> PAGE 3
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<PAGE> PAGE 4
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<PAGE> PAGE 5
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<PAGE> PAGE 6
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SIGNATURE JAMES S. RIEPE
TITLE VICE PRESIDENT
[ARTICLE] 6
[CIK] 0000316968
[NAME] T. ROWE PRICE PRIME RESERVE FUND, INC.
<TABLE>
<S> <C>
[PERIOD-TYPE] 6-MOS
[FISCAL-YEAR-END] MAY-31-1995
[PERIOD-END] NOV-30-1994
[INVESTMENTS-AT-COST] 3865955
[INVESTMENTS-AT-VALUE] 3863645
[RECEIVABLES] 36722
[ASSETS-OTHER] 105
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 3900472
[PAYABLE-FOR-SECURITIES] 49431
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 40814
[TOTAL-LIABILITIES] 90245
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 3814239
[SHARES-COMMON-STOCK] 3815397
[SHARES-COMMON-PRIOR] 3632478
[ACCUMULATED-NII-CURRENT] 2113
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] 0
[OVERDISTRIBUTION-GAINS] (3835)
[ACCUM-APPREC-OR-DEPREC] (2310)
[NET-ASSETS] 3810227
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 88065
[OTHER-INCOME] 0
[EXPENSES-NET] 12812
[NET-INVESTMENT-INCOME] 75253
[REALIZED-GAINS-CURRENT] (9)
[APPREC-INCREASE-CURRENT] 30
[NET-CHANGE-FROM-OPS] 75274
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (75227)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 2998278
[NUMBER-OF-SHARES-REDEEMED] 2887574
[SHARES-REINVESTED] 72221
[NET-CHANGE-IN-ASSETS] 182972
[ACCUMULATED-NII-PRIOR] 2106
[ACCUMULATED-GAINS-PRIOR] 0
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] (3826)
[GROSS-ADVISORY-FEES] 7244
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 12812
[AVERAGE-NET-ASSETS] 3676173
[PER-SHARE-NAV-BEGIN] 1.
[PER-SHARE-NII] .02
[PER-SHARE-GAIN-APPREC] 0
[PER-SHARE-DIVIDEND] .02
[PER-SHARE-DISTRIBUTIONS] 0
[RETURNS-OF-CAPITAL] 0
[PER-SHARE-NAV-END] 1.
[EXPENSE-RATIO] .70
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
</TABLE>
