AMGEN INC
DEF 14A, 1994-03-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>


                            SCHEDULE 14A INFORMATION
                   Proxy Statement Pursuant to Section 14(a) of
                       the Securities Exchange Act of 1934




Filed by the Registrant /x/

Filed by a Party other than the Registrant / /

Check the appropriate box:

/ /   Preliminary Proxy Statement


/x/   Definitive Proxy Statement


/ /   Definitive Additional Materials


/ /   Soliciting Material Pursuant to Section 240.14a-11(c) or Section
      240.142-12

                            AMGEN INC.
___________________________________________________________________________
           (Name of Registrant as Specified In Its Charter)


                            AMGEN INC.
___________________________________________________________________________
               (Name of Person(s) Filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box):

/x/   $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), or 14a-6(j)(2)

/ /   $500 per each party to the controversy pursuant to Exchange Act Rule
      14a-6(i)(3)

/ /   Fee computed on table below per Exchange Act Rules 14a-6(i)(4)
      and 0-11

      1)    Title of each class of securities to which transaction applies:
            _______________________________________________________________

      2)    Aggregate number of securities to which transaction applies:
            _______________________________________________________________

      3)    Per unit price or other underlying value of transaction computed
            pursuant to Exchange Act Rule 0-11:*
            _______________________________________________________________

      4)    Proposed maximum aggregate value of transaction:
            _______________________________________________________________

*     Set forth the amount on which the filing fee is calculated and state how
      it was determined.

/ /   Check box if any part of the fee is offset as provided by Exchange Act
      Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
      paid previously. Identify the previous filing by registration statement
      number, or the Form or Schedule and the date of its filing.

      1)    Amount Previously Paid:
            _______________________________________________________________

      2)    Form, Schedule or Registration Statement No.:
            _______________________________________________________________

      3)    Filing Party:
            _______________________________________________________________

      4)    Date Filed:
            _______________________________________________________________





<PAGE>
                                                                          [LOGO]

                        (AMGEN LETTERHEAD WILL BE USED)

March 28, 1994

DEAR STOCKHOLDER:

    You  are invited to attend the Annual  Meeting of Stockholders of Amgen Inc.
to be held on Tuesday, April 26, 1994, at 10:30 A.M., PDT, at the Century  Plaza
Hotel and Tower, 2025 Avenue of the Stars, Los Angeles, California.

    At  this year's meeting, you are asked  to elect three directors, to approve
the material terms of the Company's performance based Management Incentive  Plan
and  to ratify  the appointment  of the  independent auditors.  The accompanying
Notice of Meeting and Proxy Statement  describe these proposals. We urge you  to
read this information carefully.

    Your  Board of Directors unanimously believes  that election of its nominees
as directors, approval of the material terms of the Company's performance  based
Management  Incentive Plan  and ratification  of its  appointment of independent
auditors are in  the best  interests of Amgen  Inc. and  its stockholders,  and,
accordingly, recommends a vote FOR Items 1, 2 and 3 on the enclosed proxy card.

    In  addition to the formal business to be transacted, management will make a
presentation on  developments of  the  past year  and  respond to  comments  and
questions of general interest to stockholders.

    I  personally  look forward  to greeting  those  Amgen stockholders  able to
attend the meeting. If  you plan to attend  the Annual Meeting, please  complete
and  return the reply card  enclosed with the Proxy  Statement, and we will send
you a map with directions to the Century Plaza Hotel and Tower and an  admission
ticket to the Annual Meeting.

    It  is important that your  shares be represented and  voted, whether or not
you plan to attend the Annual Meeting. THEREFORE, PLEASE SIGN, DATE AND PROMPTLY
MAIL THE ENCLOSED PROXY IN THE PREPAID ENVELOPE PROVIDED.

    Thank you.

                                          Sincerely,

                                          [SIG]

                                          Gordon M. Binder
                                          CHAIRMAN OF THE BOARD

                                   [ADDRESS]
<PAGE>
                                   AMGEN INC.

                                  AMGEN CENTER
                             1840 DEHAVILLAND DRIVE
                      THOUSAND OAKS, CALIFORNIA 91320-1789

                            ------------------------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD ON APRIL 26, 1994

                            ------------------------

TO THE STOCKHOLDERS OF AMGEN INC.:

    NOTICE  IS HEREBY  GIVEN that  the Annual  Meeting of  Stockholders of Amgen
Inc., a Delaware corporation (the "Company"), will be held on Tuesday, April 26,
1994, at 10:30 A.M., PDT, at the  Century Plaza Hotel and Tower, 2025 Avenue  of
the Stars, Los Angeles, California 90067-4696, for the following purposes:

    1.  To elect three directors to hold office until 1997;

    2.    To  approve the  material  terms  of the  Company's  performance based
       Management Incentive Plan;

    3.  To ratify the selection of Ernst & Young as independent auditors of  the
       Company for the fiscal year ending December 31, 1994; and

    4.   To transact such other business as may properly come before the meeting
       or any adjournment or postponement thereof.

    The foregoing  items of  business  are more  fully  described in  the  Proxy
Statement accompanying this Notice.

    The  Board of Directors has fixed the close of business on February 28, 1994
as the record date for the  determination of stockholders entitled to notice  of
and  to  vote at  this Annual  Meeting  and at  any continuation  or adjournment
thereof.

                                          By Order of the Board of Directors

                                          [SIG]

                                          Thomas E. Workman, Jr.
                                          SECRETARY

Thousand Oaks, California
March 28, 1994

    ALL STOCKHOLDERS  ARE CORDIALLY  INVITED TO  ATTEND THE  MEETING IN  PERSON.
WHETHER OR NOT YOU EXPECT TO ATTEND THE MEETING, PLEASE COMPLETE, DATE, SIGN AND
RETURN  THE  ENCLOSED PROXY  AS PROMPTLY  AS  POSSIBLE IN  ORDER TO  ENSURE YOUR
REPRESENTATION AT THE MEETING. A PREPAID ENVELOPE IS ENCLOSED FOR THAT  PURPOSE.
EVEN  IF YOU HAVE VOTED YOUR  PROXY, YOU MAY STILL VOTE  IN PERSON IF YOU ATTEND
THE MEETING. PLEASE NOTE, HOWEVER, THAT IF  YOUR SHARES ARE HELD OF RECORD BY  A
BROKER,  BANK OR OTHER NOMINEE  AND YOU WISH TO ATTEND  AND VOTE AT THE MEETING,
YOU MUST OBTAIN FROM SUCH BROKER, BANK OR OTHER NOMINEE, A PROXY ISSUED IN  YOUR
NAME.
<PAGE>
                                   AMGEN INC.
                                  AMGEN CENTER
                             1840 DEHAVILLAND DRIVE
                      THOUSAND OAKS, CALIFORNIA 91320-1789

                            ------------------------

                                PROXY STATEMENT

                            ------------------------

                 INFORMATION CONCERNING SOLICITATION AND VOTING

GENERAL

    The  enclosed proxy is  solicited on behalf  of the Board  of Directors (the
"Board of Directors" or the "Board") of Amgen Inc., a Delaware corporation  (the
"Company"  or "Amgen"), for use at the Annual Meeting of Stockholders to be held
on Tuesday, April 26, 1994,  at 10:30 A.M., PDT,  (the "Annual Meeting"), or  at
any  continuation or adjournment thereof, for  the purposes set forth herein and
in the accompanying Notice of Annual Meeting. The Annual Meeting will be held at
the Century  Plaza Hotel  and Tower,  2025  Avenue of  the Stars,  Los  Angeles,
California 90067-4696.

SOLICITATION

    The  Company will bear the entire cost of solicitation of proxies, including
preparation, assembly and  mailing of this  proxy statement, the  proxy and  any
additional   information  furnished  to  stockholders.  Copies  of  solicitation
materials  will  be  furnished  to  banks,  brokerage  houses,  fiduciaries  and
custodians  holding shares of the Company's Common Stock (the "Common Stock") in
their names which are beneficially owned by others to forward to such beneficial
owners. The Company  may reimburse  persons representing  beneficial owners  for
their  costs of forwarding the solicitation  material to such beneficial owners.
Original solicitation  of proxies  by  mail may  be supplemented  by  telephone,
telegram  or  personal  solicitation  by directors,  officers  or  other regular
employees of the Company. No additional compensation will be paid to  directors,
officers  or other regular employees for such services. In addition, the Company
has retained D. F.  King & Co.,  Inc. to assist in  the solicitation of  proxies
from brokers, bank nominees and other institutional holders for a fee of $7,000,
plus reimbursement of out-of-pocket expenses.

    The Company intends to mail this proxy statement and accompanying proxy card
on  or about March 28, 1994, to all  stockholders entitled to vote at the Annual
Meeting.

STOCKHOLDER PROPOSALS

    Proposals of stockholders that are intended to be presented at the Company's
1995 Annual Meeting of Stockholders (the "1995 Annual Meeting") must be received
by the Company not later than November 28,  1994 in order to be included in  the
proxy statement and proxy relating to the 1995 Annual Meeting.

VOTING RIGHTS AND OUTSTANDING SHARES

    Only  holders of record of Common Stock at the close of business on February
28, 1994 will be entitled to notice of and to vote at the Annual Meeting. At the
close of business on February 28,  1994, there were outstanding and entitled  to
vote 133,829,429 shares of Common Stock. Stockholders of record on such date are
entitled  to one vote for each  share of Common Stock held  on all matters to be
voted upon at the meeting.

    All votes will be tabulated by  the inspector of election appointed for  the
Annual  Meeting, who  will separately  tabulate affirmative  and negative votes,
abstentions and  broker  non-votes.  Abstentions will  be  counted  towards  the
tabulation  of votes  cast on proposals  presented to the  stockholders and will
have the same effect as negative votes. Broker non-votes are not counted for any
purpose in determining whether a matter has been approved.

                                       1
<PAGE>
REVOCABILITY OF PROXIES

    Any person giving  a proxy pursuant  to this solicitation  has the power  to
revoke  it at any time before it is voted.  It may be revoked by filing with the
Secretary of  the Company  at the  Company's principal  executive office,  Amgen
Center,  1840 Dehavilland Drive, Thousand Oaks, California 91320-1789, Mail Stop
10-2-E-400, a written notice  of revocation or a  duly executed proxy bearing  a
later  date, or it may be revoked by attending the meeting and voting in person.
Attendance at the meeting will not, by itself, revoke a proxy.

                                   PROPOSAL 1
                             ELECTION OF DIRECTORS

    The Company's Restated Certificate of Incorporation and Bylaws provide  that
the  Board  of  Directors  shall  be  divided  into  three  classes,  each class
consisting, as  nearly  as  possible,  of  one-third  of  the  total  number  of
directors,  with each class having a three-year term. Vacancies on the Board may
be filled only by persons  elected by a majority  of the remaining directors.  A
director  elected by the Board to fill a vacancy (including a vacancy created by
an increase in the Board of Directors) will serve for the remainder of the  full
term  of the  class of directors  in which  the vacancy occurred  and until such
director's successor is elected and qualified, or until such director's  earlier
death, resignation or removal.

    The  Board of  Directors is presently  comprised of nine  members. There are
three directors in the class  whose term of office expires  in 1994 and who  are
nominees  for election to the Board. Dr. Baddour, Mr. Binder and Mr. Johnson are
currently  directors  of  the  Company  who  were  previously  elected  by   the
stockholders.  If elected at the Annual Meeting, each of Dr. Baddour, Mr. Binder
and Mr.  Johnson  would  serve until  the  1997  Annual Meeting  and  until  his
successor  is elected  and qualified,  or until  such director's  earlier death,
resignation or removal.

    Directors are  elected by  a plurality  of the  votes present  in person  or
represented  by proxy  and entitled  to vote  at the  Annual Meeting.  It is the
intention of the persons named in the enclosed proxy, unless authorization to do
so is withheld, to  vote the proxies  received by them for  the election of  the
three  nominees named below. If, prior to the Annual Meeting, any nominee should
become unavailable for election, an event which currently is not anticipated  by
the Board, the proxies will be voted for the election of such substitute nominee
or  nominees as the  Board of Directors  may propose. Each  person nominated for
election has agreed to serve if elected and management has no reason to  believe
that any nominee will be unable to serve.

    Set  forth below is  biographical information for  each person nominated and
for each person  whose term  of office  as a  director will  continue after  the
Annual Meeting.

NOMINEES FOR ELECTION FOR A THREE-YEAR TERM EXPIRING AT THE 1997 ANNUAL MEETING

RAYMOND F. BADDOUR

    Dr.  Raymond F.  Baddour, age 69,  has served  as a director  of the Company
since October  1980. Prior  to July  1, 1989,  Dr. Baddour  was Lammot  du  Pont
Professor  of Chemical Engineering at the Massachusetts Institute of Technology.
As of July 1, 1989, Dr. Baddour became Lammot du Pont Professor Emeritus.

GORDON M. BINDER

    Mr. Gordon M. Binder, age 58, has served as a director of the Company  since
October  1988. He joined the  Company in 1982 as  Vice President-Finance and was
named Senior  Vice President-Finance  in  February 1986.  In October  1988,  Mr.
Binder was elected to the position of Chief Executive Officer. In July 1990, Mr.
Binder was elected to the position of Chairman of the Board.

FRANKLIN P. JOHNSON, JR.

    Mr.  Franklin  P. Johnson,  Jr., age  65, has  served as  a director  of the
Company since  October 1980.  He  is the  general  partner of  Asset  Management
Partners, a venture capital limited partnership.

                                       2
<PAGE>
Mr.  Johnson has  been a  private venture  capital investor  for more  than five
years. He is also Chairman of the Board of Boole & Babbage, Inc. and a  director
of  BioSurface Technology, Inc., IDEC  Pharmaceuticals Corporation, Ross Stores,
Inc., Tandem Computers Incorporated, Teradyne Inc. and Trinzic Corporation.

    THE BOARD OF DIRECTORS RECOMMENDS A VOTE IN FAVOR OF EACH NAMED NOMINEE.

DIRECTORS CONTINUING IN OFFICE UNTIL THE 1995 ANNUAL MEETING

STEVEN LAZARUS

    Mr. Steven Lazarus, age 62,  has served as a  director of the Company  since
May  1987. He has been the President  and Chief Executive Officer of the Argonne
National Laboratory/The University of  Chicago Development Corporation  ("ARCH")
since  it  was  formed in  October  1986. ARCH  is  involved in  the  process of
transforming scientific  discoveries into  viable high  technology products  and
services.  He  is also  the Managing  Partner of  ARCH Venture  Fund, L.P.   Mr.
Lazarus also has  been associate dean  at the Graduate  School of Business,  the
University of Chicago, since October 1986. Mr. Lazarus also serves as a director
of  Cobra  Industries,  Inc., Illinois  Superconductor  Corporation  and Primark
Corporation; and as Vice Chairman of the Board of Directors of The  Northwestern
Healthcare Network, Chicago, Illinois.

EDWARD J. LEDDER

    Mr.  Edward J. Ledder, age 76, has served as a director of the Company since
January 1991. In April 1981, Mr. Ledder retired as Chairman and Chief  Executive
Officer  of  Abbott Laboratories,  a corporation  in  the principal  business of
developing and providing human healthcare  products, where he had been  employed
in  various executive positions since 1939. Mr. Ledder also serves as a director
of Alliance International Healthcare  Fund and is the  Chairman of the Board  of
Pool Energy Services Company.

GILBERT S. OMENN

    Dr.  Gilbert S. Omenn, age 52, has served as a director of the Company since
January 1987. He  has been Dean  of the  School of Public  Health and  Community
Medicine  at the University  of Washington for  more than five  years. Dr. Omenn
also is a director of Immune Response Corporation and Rohm & Haas Company.

DIRECTORS CONTINUING IN OFFICE UNTIL THE 1996 ANNUAL MEETING

WILLIAM K. BOWES, JR.

    Mr. William K. Bowes, Jr., age 67,  has served as a director of the  Company
since  April 1980.  He has been  a general  partner of U.S.  Venture Partners, a
venture capital investment entity, since July  1981. Mr. Bowes also serves as  a
director  of Glycomed Incorporated, Xoma Corporation,  and a number of privately
held U.S. Venture Partners  portfolio companies and serves  as the President  of
Presidio Management Group.

    On  April 21,  1989, Mr.  Bowes entered  into a  negotiated settlement under
which he admitted  to misdemeanor failure  to file California  state income  tax
returns for the years 1983 through 1986 with no intent to evade taxes. Mr. Bowes
had  paid taxes as specified  by the California Franchise  Tax Board during this
period and paid the balance due in 1988.

BERNARD H. SEMLER

    Mr. Bernard H. Semler, age 76, has served as a director of the Company since
August 1982. He has been a management  consultant since July 1982. From 1974  to
July 1982, he was Executive Vice President-Finance of Abbott Laboratories.

KEVIN W. SHARER

    Mr.  Kevin W. Sharer, age 46, has served  as a director and as President and
Chief Operating Officer of the Company since November 1992. Prior to joining the
Company, Mr. Sharer served as President of

                                       3
<PAGE>
the Business  Markets  Division of  MCI  Communications Corporation  ("MCI"),  a
telecommunications  company, from April 1989 to October 1992. From February 1984
until joining MCI  in April 1989,  Mr. Sharer had  served in numerous  executive
capacities at General Electric Company.

BOARD COMMITTEES AND MEETINGS

    The Board of Directors, which held six meetings during the fiscal year ended
December  31,  1993,  has  an  Audit  Committee,  a  Compensation  Committee, an
Executive Committee, a Nominating Committee and a Strategy Committee.

    The Audit  Committee  recommends  engagement of  the  Company's  independent
auditors  and approves services performed by such auditors, including the review
and evaluation of  the Company's accounting  system and its  system of  internal
controls  in connection with the Company's  annual audit. During the fiscal year
ended December 31, 1993, the Audit Committee met three times. Mr. Semler  served
as  Chairman, and Messrs. Bowes  and Johnson and Dr.  Omenn served as members of
the Audit Committee.

    The  Compensation  Committee  sets  guidelines  for  the  administration  of
salaries,  makes recommendations  for officers'  salaries, administers incentive
compensation and awards  stock options  to employees and  consultants under  the
Company's  stock  option  plans and  otherwise  determines  compensation levels.
During the fiscal year ended December  31, 1993, the Compensation Committee  met
six times. Mr. Semler served as Chairman, and Messrs. Lazarus and Ledder and Dr.
Baddour served as members of the Compensation Committee.

    The  Executive Committee may exercise, when the Board of Directors is not in
session, all powers of the Board of Directors in the management of the  business
and  affairs of the  Company to the extent  permitted by law,  the Bylaws of the
Company and specifically granted  by the Board of  Directors. During the  fiscal
year  ended December 31, 1993, the Executive  Committee did not meet. Mr. Binder
served as  Chairman, and  Messrs. Bowes  and Johnson  served as  members of  the
Executive Committee.

    The  Nominating  Committee interviews,  evaluates, nominates  and recommends
individuals for membership on  the Company's Board  of Directors and  committees
thereof  and nominates  specific individuals  to be  elected as  officers of the
Company by  the  Board of  Directors.  The Nominating  Committee  will  consider
nominees  for directors nominated by stockholders  upon submission in writing to
the Secretary of the Company of the names of such nominees, together with  their
qualifications  for  service as  a director  of  the Company.  In order  for any
nominees for  directors  nominated  by  stockholders to  be  considered  by  the
Nominating  Committee, such nominations must be submitted no later than December
1st of  the year  preceding the  Annual Meeting.  During the  fiscal year  ended
December  31,  1993, the  Nominating Committee  met twice.  Mr. Bowes  served as
Chairman, and Mr.  Johnson and  Dr. Omenn served  as members  of the  Nominating
Committee.

    The  Strategy  Committee  meets with  management  of the  Company  to review
strategies and proposals for collaborations and licensing of technology.  During
the  fiscal year ended December 31, 1993, the Strategy Committee met four times.
Mr. Lazarus served as Chairman, and Mr.  Ledder and Dr. Omenn served as  members
of the Strategy Committee.

    During  the  fiscal  year ended  December  31,  1993, all  of  the directors
attended at least 75% of the total number of meetings of the Board of  Directors
and committees on which they served.

                                   PROPOSAL 2
  APPROVAL OF THE MATERIAL TERMS OF THE COMPANY'S PERFORMANCE BASED MANAGEMENT
                                 INCENTIVE PLAN

    The  Omnibus Budget Reconciliation  Act of 1993 placed  a one million dollar
annual limit  on the  amount  of non-performance  based compensation  for  Named
Executive  Officers that may be  deducted by the Company  for Federal income tax
purposes. Compensation based on the achievement of

                                       4
<PAGE>
pre-established performance goal(s)  set by  the Compensation  Committee of  the
Board  of Directors under a performance based incentive plan and approved by the
affirmative vote  of the  holders of  a majority  of the  voting shares  of  the
Company's stock will be excluded from the limitation.

    The Compensation Committee of the Board of Directors determines and approves
the  terms  and performance  goals of  the  Company's Management  Incentive Plan
("MIP") at  the beginning  of each  fiscal year.  MIP participants  include  all
executive  officers  of  the Company  and  certain  other key  employees.  For a
description of  the  MIP, please  refer  to the  Compensation  Committee  Report
contained herein.

    The  MIP is designed  to reward participants for  their contributions to the
achievement of  the  Company-wide  performance  goals. No  awards  are  made  to
participants,  regardless of  their own  level of  achievement or  the Company's
achievement of other goals,  unless either the Company-wide  goal for Return  on
Capital  Employed ("ROCE") or  for Growth in  Revenue is achieved  to create the
pool. Consequently,  the  benefits  or  amounts that  will  be  received  by  or
allocated  to any of the Named Executive Officers (as hereafter defined) are not
determinable prior to the  time financial results are  available for the  fiscal
year  with respect  to which MIP  awards are payable.  See "SUMMARY COMPENSATION
TABLE" for amounts earned pursuant to the MIP by the Named Executive Officers in
the fiscal  years ended  December 31,  1991, 1992  and 1993.  Target awards  for
participants  are established pursuant to a  percentage formula relating to Base
Salary. The  MIP provides  for awards  of  up to  150% of  the target  award  to
participants  who substantially exceed  their individual performance objectives.
In no event may the award to any participant exceed $900,000.

    The Board  of  Directors  has  directed  that  the  material  terms  of  the
performance based MIP be submitted to the Company's stockholders for approval at
the  1994  Annual Meeting.  Stockholder approval  of the  material terms  of the
performance based MIP  is required  for the  Company to  be able  to deduct  for
Federal income tax purposes compensation in excess of one million dollars to any
Named  Executive Officer for fiscal years beginning in 1994. If the above stated
Company-wide performance based MIP and the  maximum annual award payable to  any
of  the  Named  Executive Officers  pursuant  to  the MIP  are  approved  by the
Company's stockholders  at  the 1994  Annual  Meeting, such  approval  shall  be
effective until the earlier of (i) the 1999 Annual Meeting; (ii) modification by
the  Compensation Committee of  the Board of Directors  of the performance based
MIP; or (iii) modification  of the maximum  annual award payable  to any of  the
Named Executive Officers pursuant to the MIP.

    The  affirmative vote of the holders of  a majority of the shares present in
person or represented  by proxy  and entitled  to vote  at the  meeting will  be
required to approve the material terms of the Company's performance based MIP.

    THE BOARD OF DIRECTORS RECOMMENDS A VOTE IN FAVOR OF PROPOSAL 2.

                                   PROPOSAL 3
               RATIFICATION OF SELECTION OF INDEPENDENT AUDITORS

    The  Board  of  Directors  has  selected  Ernst  &  Young  as  the Company's
independent auditors  for the  fiscal year  ending December  31, 1994,  and  has
further  directed that management  submit the selection  of independent auditors
for ratification by the  stockholders at the Annual  Meeting. Ernst & Young  has
audited  the  Company's financial  statements since  the Company's  inception in
1980. Representatives of Ernst & Young are expected to be present at the  Annual
Meeting  and will have an opportunity to make  a statement if they so desire and
will be available to respond to appropriate questions.

    Stockholder ratification of the selection of Ernst & Young as the  Company's
independent  auditors  is not  required by  the  Company's Bylaws  or otherwise.
However, the  Board  is  submitting  the  selection of  Ernst  &  Young  to  the
stockholders  for ratification  as a matter  of good corporate  practice. If the
stockholders fail to ratify the selection, the Board will reconsider whether  or
not to retain that firm.

                                       5
<PAGE>
Even  if the selection were ratified, the Board in its discretion may direct the
appointment of a different  independent accounting firm at  any time during  the
year  if the Board determines that such a  change would be in the best interests
of the Company and its stockholders.

    The affirmative vote of the holders of  a majority of the shares present  in
person  or represented  by proxy  and entitled  to vote  at the  meeting will be
required to ratify the selection of Ernst & Young.

    THE BOARD OF DIRECTORS RECOMMENDS A VOTE IN FAVOR OF PROPOSAL 3.

                 SECURITY OWNERSHIP OF DIRECTORS AND EXECUTIVE
                     OFFICERS AND CERTAIN BENEFICIAL OWNERS

    The following table sets forth  certain information regarding the  ownership
of  the Company's Common  Stock as of  December 31, 1993  by: (i) each director;
(ii) the  Company's Chief  Executive Officer  and each  of its  other four  most
highly  compensated executives ("Named Executive  Officers") for the fiscal year
ended December 31, 1993; and (iii)  all directors and executive officers of  the
Company  as a group. The Company is not  aware of any person who is a beneficial
owner of more than 5% of its Common Stock:

<TABLE>
<CAPTION>
                                                                        SHARES OF COMMON
                                                                       STOCK BENEFICIALLY
                                                                          OWNED (1)(2)
                                                                       -------------------
                                                                                   PERCENT
                                                                        NUMBER       OF
                          BENEFICIAL OWNER                             OF SHARES    TOTAL
- --------------------------------------------------------------------   ---------   -------
<S>                                                                    <C>         <C>
Raymond F. Baddour..................................................     107,750      *
Gordon M. Binder....................................................     944,118      *
William K. Bowes, Jr................................................   1,502,600     1.1
Franklin P. Johnson, Jr. (3)........................................     745,800      *
Steven Lazarus......................................................      56,400      *
Edward J. Ledder....................................................      24,000      *
Gilbert S. Omenn....................................................      85,400      *
Bernard H. Semler (4)...............................................     115,951      *
Kevin W. Sharer.....................................................      20,626      *
Daniel Vapnek (5)...................................................     357,874      *
N. Kirby Alton (6)..................................................      65,602      *
Lowell E. Sears.....................................................      49,757      *
All directors and executive officers as a group (17
 persons) (3)(4)(5)(6)..............................................   4,551,522     3.3
<FN>
- ------------------------
 *    Less than 1%
(1)   This table  is based  upon information  supplied by  directors,  executive
      officers  and Schedules 13D and 13G, if any, filed with the Securities and
      Exchange  Commission  (the  "SEC").  Unless  otherwise  indicated  in  the
      footnotes and subject to community property laws where applicable, each of
      the  stockholders has sole voting and/or  investment power with respect to
      the shares beneficially owned.
(2)   Includes shares which the  directors and the  Named Executive Officers  of
      the  Company had the right to acquire  on or before March 1, 1994 pursuant
      to outstanding  options  and  warrants,  as  follows:  Dr.  Baddour-36,068
      shares;   Mr.   Binder-754,316  shares;   Mr.  Bowes-76,400   shares;  Mr.
      Johnson-150,800  shares;  Mr.  Lazarus-42,077  shares;  Mr.  Ledder-22,400
      shares;   Dr.   Omenn-85,400   shares;  Mr.   Semler-65,686   shares;  Mr.
      Sharer-20,000 shares; Dr. Vapnek-324,425 shares; Dr. Alton-25,400  shares;
      Mr.  Sears-45,770 shares;  and all directors  and executive  officers as a
      group-2,010,192 shares.
</TABLE>

                                       6
<PAGE>
<TABLE>
<S>   <C>
(3)   Includes 583,000  shares  held by  Asset  Management Partners,  a  venture
      capital  limited partnership, of which Mr. Johnson is the general partner.
      As the  general partner,  Mr. Johnson  may be  deemed to  have voting  and
      investment power as to all of these shares, and therefore may be deemed to
      be a beneficial owner of such shares.
(4)   Includes  5,154 shares  held by  a trust for  the benefit  of Mr. Semler's
      wife.
(5)   Includes 5,350 shares held by one of Dr. Vapnek's children.
(6)   Excludes 2,312 shares held  by trusts established for  the benefit of  Dr.
      Alton's  children. Dr.  Alton disclaims  beneficial ownership  of all such
      shares.
</TABLE>

    In March and  June 1993, the  Company exercised its  option to purchase  the
Class  A  and  Class B  Limited  Partnership interests,  respectively,  of Amgen
Clinical Partners, L.P. (the "Partnership") pursuant to the partnership purchase
agreement dated as of March 12, 1993 by and among the Company, the  Partnership,
Amgen  Development Corporation,  and each  of the  Class A  and Class  B Limited
Partners of the Partnership. As a result of the Company exercising such  option,
each  holder of a  Limited Partnership interest  acquired contractual contingent
payment rights based on the number  of such holder's former Limited  Partnership
interests.  The contractual contingent payment rights are not voting securities.
The following table sets  forth certain information  regarding the ownership  of
the  Company's contractual contingent payment rights as of December 31, 1993 by:
(i) each  director;  (ii) each  of  the five  Named  Executive Officers  of  the
Company;  and (iii)  all directors  and executive officers  of the  Company as a
group:

<TABLE>
<CAPTION>
                                                                              CONTRACTUAL
                                                                               CONTINGENT
                                                                             PAYMENT RIGHTS
                                                                              BENEFICIALLY
                                                                               OWNED (1)
                                                                          --------------------
                                                                                       PERCENT
                                                                           NUMBER        OF
                           BENEFICIAL OWNER                               OF RIGHTS     TOTAL
- -----------------------------------------------------------------------   ---------    -------
<S>                                                                       <C>          <C>
Raymond F. Baddour.....................................................          1        *
Gordon M. Binder.......................................................          1        *
William K. Bowes, Jr...................................................          2        *
Franklin P. Johnson, Jr. (2)...........................................          4        *
Steven Lazarus.........................................................         -0-       *
Edward J. Ledder.......................................................         -0-       *
Gilbert S. Omenn.......................................................        1/2        *
Bernard H. Semler......................................................          1        *
Kevin W. Sharer........................................................         -0-       *
Daniel Vapnek..........................................................        1/2        *
N. Kirby Alton.........................................................        1/4        *
Lowell E. Sears........................................................        1/4        *
All directors and executive officers as a group (17 persons) (2).......       10.5       1.3
<FN>
- ------------------------
 *    Less than 1%
(1)   This table  is  based  upon  information supplied  by  the  directors  and
      executive  officers  of the  Company.  Unless otherwise  indicated  in the
      footnotes and subject  to community property  laws where applicable,  each
      holder  of a contractual  contingent payment right(s)  has sole investment
      power with respect to such right(s) beneficially owned.
(2)   Includes four rights held by Asset Management Partners, a venture  capital
      limited  partnership, of which Mr. Johnson  is the general partner. As the
      general partner, Mr. Johnson may be deemed to have investment power as  to
      all  of these rights, and therefore may be deemed to be a beneficial owner
      of such rights.
</TABLE>

                                       7
<PAGE>
                             EXECUTIVE COMPENSATION

COMPENSATION OF DIRECTORS

    During the period January 1, 1993  through June 30, 1993, each  non-employee
director  received a quarterly  retainer of $3,000 (plus  $1,000 for a Committee
Chairman) and  a per  meeting fee  of $1,000  (plus $750  for Committee  members
attending  a committee  meeting, up  to a  maximum of  $1,500 for  all committee
meetings held on the same day). During the period July 1, 1993 through  December
31,  1993, each  non-employee director received  a quarterly  retainer of $3,750
(plus $1,500 for a  Committee Chairman) and  a per meeting  fee of $1,250  (plus
$750  for Committee members  attending a committee  meeting, up to  a maximum of
$1,500 for all  committee meetings held  on the  same day). In  the fiscal  year
ended  December 31, 1993, the total  compensation paid to non-employee directors
was $214,500.  The members  of the  Board  of Directors  also are  eligible  for
reimbursement for their expenses incurred in connection with attendance at Board
and  committee meetings in  accordance with Company policy.  There are no family
relationships among any directors of the Company.

    Option grants under the 1987  Directors' Stock Option Plan (the  "Directors'
Plan")  are non-discretionary. On January 27 of  each year (or the next business
day  should  such  date  be  a  Saturday,  Sunday  or  a  legal  holiday),  each
non-employee  director  or an  affiliate of  any  such non-employee  director is
automatically granted under the Directors'  Plan, without further action by  the
Company, the Board of Directors or the stockholders of the Company, an option to
purchase  shares of Common Stock of the Company. The number of shares subject to
such option is determined by multiplying  3,500 by a fraction, the numerator  of
which  is $40 per share and the denominator of which is the fair market value of
the Common Stock  of the  Company on  the date of  grant. The  number of  shares
granted will be rounded to the nearest 100 shares (rounding up if 50 shares). In
no event will the number of shares subject to such option exceed 5,000 shares or
be  less than 2,000 shares.  The minimum and maximum  number of shares of Common
Stock to be granted under the Directors' Plan will not be adjusted for any stock
split, combination of shares or Common Stock dividend.

    Each person who after January 27 and prior to November 1 of any year becomes
a non-employee director will, upon the  date such person becomes a  non-employee
director,  automatically be granted an option to purchase shares of Common Stock
of the Company. The number of shares subject to the option will be determined as
described in the immediately preceding paragraph.

    The purchase price for  shares acquired upon exercise  of an option  granted
under the Directors' Plan may be paid in cash or by delivery of shares of Common
Stock  that have  been held  for the period  required to  avoid a  charge to the
earnings of the Company. Any shares so surrendered shall be valued at their fair
market value on  the date  of exercise. The  exercise price  of options  granted
under  the Directors'  Plan is  equal to 100%  of the  fair market  value of the
underlying stock on the date of the option grant.

    An optionee is entitled  to a reload option  ("Reload Option") in the  event
the  optionee exercises his or her option,  in whole or in part, by surrendering
other shares of Common Stock of  the Company held by such non-employee  director
in  accordance with the Directors'  Plan and the terms  of the option grant. Any
such Reload Option (i) will be for a  number of shares of Common Stock equal  to
the  number of shares of Common Stock surrendered as part or all of the exercise
price of the original option; (ii) will have an expiration date that is the same
as the expiration date of the original  option; and (iii) will have an  exercise
price that is equal to 100% of the fair market value of the Common Stock subject
to  the Reload Option on  the date of exercise of  the original option. Any such
Reload Option will be subject to the availability of sufficient shares under the
Directors' Plan. There will be no Reload Option on a Reload Option.

    Options granted to a non-employee director under the Directors' Plan may not
be exercised: (a) unless such director has, at the date of grant, provided three
years of prior continuous service as a non-employee director, in which case such
option will vest upon grant but will  not be exercisable until six months  after
the  date of grant, or (b) until the  date upon which such director has provided
one year

                                       8
<PAGE>
of continuous service as a non-employee director following the date of grant  of
such  option, whereupon such option will  become fully exercisable in accordance
with its  terms. No  option under  the  Directors' Plan  is exercisable  by  the
optionee  after the expiration of ten years from the date the original option is
granted.

    During the fiscal year  ended December 31, 1993,  the Company granted  under
the  Directors' Plan an  aggregate of 19,512 non  qualified stock options, which
amount included options for 2,300 shares, at an exercise price of $60 per share,
that were granted to each of the current incumbent directors in January 1993 and
Reload Options granted in March and June 1993 to Messrs. Lazarus and Semler  for
1,677 and 1,735 shares at exercise prices of $37.50 and $36.25, respectively.

COMPENSATION OF EXECUTIVE OFFICERS

    The  following table shows for  the years ended December  31, 1993, 1992 and
1991, respectively, certain compensation  awarded or paid to,  or earned by  the
Named Executive Officers:

                         SUMMARY COMPENSATION TABLE (1)

<TABLE>
<CAPTION>
                                                                                     LONG TERM
                                                                                   COMPENSATION
                                                   ANNUAL COMPENSATION             -------------
                                        -----------------------------------------   SECURITIES
                                                                    OTHER ANNUAL    UNDERLYING         ALL OTHER
NAME AND PRINCIPAL POSITION    YEAR     SALARY ($)(2)  BONUS ($)(3) COMPENSATION    OPTIONS (#)   COMPENSATION ($)(4)
- ---------------------------  ---------  -------------  -----------  -------------  -------------  -------------------
<S>                          <C>        <C>            <C>          <C>            <C>            <C>
Gordon M. Binder, Chief           1993      466,676       487,057                      24,390          130,428(10)
 Executive Officer,               1992      400,016       407,351                      20,000           15,907
 Chairman of the Board and        1991      332,514       240,319                      15,000
 Director
Kevin W. Sharer, President,       1993      360,000       305,908      893,037(6)      70,200(7)        48,237(10)
 Chief Operating Officer          1992       64,154       200,000                     150,000(8)         5,045
 and Director                     1991       --            --                           --
Daniel Vapnek, Senior Vice        1993      273,348       223,807                      15,559           55,904(10)
 President, Research              1992      236,672       162,556                      15,500(9)        15,907
                                  1991      201,240       112,967                       8,400
N. Kirby Alton, Senior Vice       1993      238,348       161,573                      16,140           37,976(10)
 President, Development           1992      191,672       111,380                      22,000(9)        15,907
                                  1991      157,332        77,715                       7,500
Lowell E. Sears, Senior           1993      227,500       156,022                      16,140           35,975(10)
 Vice President,                  1992      183,336       106,944                      21,000(9)        15,907
 Asia-Pacific, and Acting         1991      154,794        69,019                       6,600
 Chief Financial
 Officer (5)
<FN>
- ------------------------
(1)   On  July 24, 1991, the  Company's Board of Directors  approved a change in
      the Company's fiscal year end from  March 31 to December 31. This  Summary
      Compensation Table reflects all compensation earned during the fiscal year
      that began January 1, 1991 and ended December 31, 1991.
(2)   Includes   amounts  deferred  out  of  compensation  under  the  Company's
      Retirement and Savings Plan otherwise payable in cash during each calendar
      year.
(3)   Bonuses pursuant to the MIP were earned in the fiscal years ended December
      31, 1991 and December 31, 1992 during the following MIP periods: (i) April
      1, 1990 through March 31, 1991; (ii) April 1, 1991 through March 31, 1992;
      and (iii) April 1, 1992 through December 31, 1992. Bonuses for fiscal year
      1991 represent 25% of the payments under  the MIP for the period April  1,
      1990 through March 31, 1991 and 75% of the payments received under the MIP
      for  the period  April 1,  1991 through  March 31,  1992. The  bonuses for
      fiscal year 1992 represent 25% of the payments received under the MIP  for
      the  period April 1, 1991 through March  31, 1992 and 100% of the payments
      received under the MIP for the  period April 1, 1992 through December  31,
      1992.  As of January 1, 1993, the MIP period corresponded to the Company's
      fiscal year. Bonuses under  the MIP for the  period April 1, 1990  through
      March  31,  1991  were  as  follows:  Mr.  Binder,  $197,790;  Dr. Vapnek,
      $125,115; Dr. Alton, $84,540;  and Mr. Sears,  $73,388. Bonuses under  the
      MIP  for the period April 1, 1991  through March 31, 1992 were as follows:
      Mr. Binder, $254,495;
</TABLE>

                                       9
<PAGE>
<TABLE>
<S>   <C>
      Dr. Vapnek, $108,918; Dr. Alton, $75,440; and Mr. Sears, $67,562.  Bonuses
      under  the MIP for the period April 1, 1992 through December 31, 1992 were
      as follows:  Mr.  Binder,  $343,727;  Dr.  Vapnek,  $135,326;  Dr.  Alton,
      $92,520; and Mr. Sears, $90,053.
(4)   As  permitted by rules  promulgated by the  SEC, no amounts  are shown for
      1991. The  Company made  contributions in  the amount  of $16,385  to  the
      Company's  Retirement and  Savings Plan  for each  of the  Named Executive
      Officers for the fiscal year ended December 31, 1993.
(5)   Mr. Sears  resigned  as  Senior Vice  President,  Asia-Pacific,  effective
      January  7, 1994 and will resign as Senior Vice President and Acting Chief
      Financial Officer effective March 31, 1994. See "CERTAIN TRANSACTIONS".
(6)   Includes a $524,330 payment to  Mr. Sharer that represents the  difference
      between  the original  cost of his  primary residence in  Virginia and the
      market value, which was less than  the original cost; $46,712 in  payments
      to  or on behalf  of Mr. Sharer  in connection with  his relocation to the
      Thousand Oaks vicinity;  and a $321,995  payment on behalf  of Mr.  Sharer
      with respect to taxes payable by him as a result of such payments.
(7)   Represents  Mr. Sharer's annual periodic stock option grant which included
      supplemental stock  options to  adjust  the grant  price for  the  options
      granted  when he was hired  by the Company to  reflect an equivalent grant
      price of approximately $50 per share.
(8)   Represents stock options granted  to Mr. Sharer when  he was hired by  the
      Company.
(9)   Represents  the sum of  the options granted  in connection with promotions
      and a reorganization  of the  Company's management  structure effected  in
      August 1992 and the annual periodic stock option grants.
(10)  The  Company's Supplemental  Retirement Plan  ("SRP") is  a non qualified,
      unfunded,  deferred  compensation  plan.  Participation  in  the  SRP   is
      available to participants in the Company's Retirement and Savings Plan who
      are affected by the Internal Revenue Code limits on the amount of employee
      compensation  that  may  be  recognized for  purposes  of  calculating the
      Company's core, matching and  performance contributions to the  Retirement
      and  Savings Plan.  The Company  credits participants  in the  SRP with an
      amount equal to the difference  between the maximum Company  contributions
      permitted  under the Retirement and Savings Plan and the amount of Company
      contributions that  such employee  would have  received, absent  statutory
      limitations.  Each  participant  in  the  SRP  is  credited  with  Company
      contributions  at  the  time   each  participant  reaches  the   statutory
      limitation(s)  under the Retirement and Savings  Plan. The SRP was adopted
      in 1993 and retroactive  participation in such plan  was approved for  the
      fiscal year ended December 31, 1993. With respect to the fiscal year ended
      December 31, 1993, participants have been credited as of December 31, 1993
      with  an amount equal to the average  return on investment that would have
      been earned if the Company's contributions under the SRP had been invested
      during the fiscal  year ended  December 31,  1993 in  the same  investment
      options,  other than Company stock, selected by a participant with respect
      to his or her Retirement and Savings Plan account. As of January 1,  1993,
      SRP  participants  also  were  credited  with  Company  contributions with
      respect to the fiscal years ended December 31, 1991 and December 31, 1992.
      With respect to the fiscal years ended December 31, 1991 and December  31,
      1992, SRP participants have been credited as of December 31, 1993 with the
      amount  by which such  Company contributions would  have increased if such
      contributions had  been  invested  as  of January  1,  1993  in  the  same
      investment  options, other than  Company stock, selected  by a participant
      with respect to  his or  her Retirement  and Savings  Plan account.  These
      credits  are  bookkeeping entries  and  represent the  Company's unsecured
      promise of  future  payment. Pursuant  to  the SRP,  the  Named  Executive
      Officers  were credited  with the  following amounts  for the  fiscal year
      ended December  31, 1991:  Mr.  Binder, $7,842;  Dr. Vapnek,  $2,249;  Dr.
      Alton,  $197; and Mr. Sears, $60. Pursuant to the SRP, the Named Executive
      Officers were  credited with  the following  amounts for  the fiscal  year
      ended  December 31,  1992: Mr. Binder,  $50,156; Dr.  Vapnek, $17,436; Dr.
      Alton, $9,029; and Mr. Sears, $7,203. Since Mr. Sharer became employed  by
      the  Company on October 28, 1992, he  did not have any amounts credited to
      him for the fiscal  years ended December 31,  1991 and December 31,  1992,
      respectively.  Pursuant  to the  SRP,  the Named  Executive  Officers were
      credited with the following amounts for the fiscal year ended December 31,
      1993: Mr. Binder, $56,045; Mr.  Sharer, $31,852; Dr. Vapnek, $19,834;  Dr.
      Alton, $12,365; and Mr. Sears, $12,327.
</TABLE>

                                       10
<PAGE>
STOCK OPTION GRANTS AND EXERCISES

    The  Company has  granted options to  its executive officers  under its 1984
Stock Option  Plan (the  "1984 Plan"),  its 1988  Stock Option  Plan (the  "1988
Plan")  and its 1991  Equity Incentive Plan (the  "1991 Plan"; collectively with
the 1984 Plan and the 1988 Plan,  the "Option Plans"). As of December 31,  1993,
options  to purchase  a total  of 16,539,032  shares had  been granted  and were
outstanding under the Option Plans for all employees, including 1,796,725 shares
granted to  the five  Named Executive  Officers.  As of  that date,  options  to
purchase  8,232,677 shares remained available for  future grant under the Option
Plans.

    The following  tables show  for the  fiscal year  ended December  31,  1993,
certain  information regarding  options granted  to, exercised  by, and  held at
fiscal year end by the Named Executive Officers:

                       OPTION GRANTS IN FISCAL YEAR 1993

<TABLE>
<CAPTION>
                                                  INDIVIDUAL GRANTS
- ----------------------------------------------------------------------------------------------------------------------
                                NUMBER OF                                                       POTENTIAL REALIZABLE
                               SECURITIES                                                     VALUE AT ASSUMED ANNUAL
                               UNDERLYING    PERCENT OF TOTAL                                   RATES OF STOCK PRICE
                                 OPTIONS      OPTIONS GRANTED   EXERCISE OR                   APPRECIATION FOR OPTION
                                 GRANTED      TO EMPLOYEES IN   BASE PRICE                            TERM (1)
NAME                          (#)(2)(3)(4)    FISCAL YEAR (5)   ($/SH) (6)   EXPIRATION DATE    5% ($)       10% ($)
- ----------------------------  -------------  -----------------  -----------  ---------------  -----------  -----------
<S>                           <C>            <C>                <C>          <C>              <C>          <C>
Gordon M. Binder............      24,390              .63%          35.875        07/01/00        356,209      830,119
Kevin W. Sharer.............      70,200(7)          1.81%          35.875        07/01/00      1,025,252    2,389,273
Daniel Vapnek...............      15,559              .40%          35.875        07/01/00        227,235      529,554
N. Kirby Alton..............      16,140              .42%          35.875        07/01/00        235,720      549,329
Lowell E. Sears.............      16,140              .42%          35.875        07/01/00        235,720      549,329
<FN>
- ------------------------
(1)   The potential realizable value is based on  the term of the option at  the
      time  of its grant which  is seven years for  the stock options granted to
      the five Named  Executive Officers  in the  table. Pursuant  to the  rules
      promulgated  by the SEC, assumed annual  stock price appreciation rates of
      5% and  10% are  used. The  potential realizable  value is  calculated  by
      assuming  that the  stock price  on the date  of grant  appreciates at the
      indicated rate, compounded annually, for the entire term of the option and
      that the option is exercised and sold on the last day of its term at  this
      appreciated stock price. No valuation method can accurately predict future
      stock  prices or option values because there are too many unknown factors.
      No gain to the optionee is possible unless the stock price increases  over
      the   option  term.  Such  a  gain   in  stock  price  would  benefit  all
      stockholders.
(2)   Under the terms  of the  Company's Option  Plans, the  Board of  Directors
      retains  discretion, subject to  plan limitations, to  modify the terms of
      outstanding options and to reprice the options. The Board of Directors has
      delegated administration of the Option Plans to the Compensation Committee
      of the Board of Directors.
(3)   The options were granted to the five Named Executive Officers in the table
      for a term of seven years, subject to earlier termination if the  optionee
      ceases  employment with the Company prior  to the vesting of such options.
      Each option agreement  contains a  provision entitling the  optionee to  a
      further  Reload Option in the event  the optionee exercises the option, in
      whole or  in  part,  by  surrendering other  shares  of  Common  Stock  in
      accordance with the Option Plans. Any such Reload Option (i) will be for a
      number  of shares of Common Stock equal  to the number of shares of Common
      Stock surrendered as  part or all  of the exercise  price of the  original
      option;  (ii)  will  have an  expiration  date  that is  the  same  as the
      expiration date of the  original option; and (iii)  will have an  exercise
      price  that is equal to 100% of the  fair market value of the Common Stock
      subject to  the Reload  Option on  the date  of exercise  of the  original
      option. There will be no Reload Option on a Reload Option.
(4)   Represents  options granted  as part of  the annual  periodic stock option
      grants extended to all  eligible employees of  the Company. Upon  vesting,
      such options become exercisable. 20% of the
</TABLE>

                                       11
<PAGE>
<TABLE>
<S>   <C>
      options  covered thereby become vested twelve  months after the grant date
      and an additional  20% of  the options  become vested  on each  successive
      anniversary  date, with  full vesting  occurring on  the fifth anniversary
      date.
(5)   Options granted to the five Named Executive Officers in the table, who are
      reporting persons for purposes  of Section 16  ("Section 16 officers")  of
      the  Securities  Exchange  Act of  1934,  represented 3.67%  of  the total
      options granted to all  employees of the Company;  and options granted  to
      all  ten Section 16 officers of the Company represented 5.67% of the total
      options granted to all employees of the Company.
(6)   The exercise price of options  must be paid: (i) in  cash at the time  the
      option is exercised, (ii) by delivery of other Common Stock of the Company
      that  has  been held  for the  period required  to avoid  a charge  to the
      Company's earnings, or (iii) at the discretion of the Board of  Directors,
      (a) pursuant to a deferred payment arrangement or (b) in any other form of
      legal  consideration acceptable to the Board of Directors. Tax withholding
      obligations related  to  exercise may  be  paid  by a  cash  payment  upon
      exercise,  by  delivery  to the  Company  of  already owned  shares  or by
      authorizing  the  Company  to  withhold  shares  otherwise  issuable  upon
      exercise, or by a combination of these methods. The options are subject to
      accelerated  vesting upon the death of the optionee while in the employ of
      the Company or within three months of termination of such employment.
(7)   Represents Mr. Sharer's annual periodic stock option grant which  included
      supplemental  stock  options to  adjust the  grant  price for  the options
      granted when he was  hired by the Company  to reflect an equivalent  grant
      price of approximately $50 per share.
</TABLE>

                AGGREGATED OPTION EXERCISES IN FISCAL YEAR 1993
                     AND FISCAL YEAR-END 1993 OPTION VALUES

<TABLE>
<CAPTION>
                                                                        NUMBER OF SECURITIES
                                                                             UNDERLYING        VALUE OF UNEXERCISED
                                                                         UNEXERCISED OPTIONS   IN-THE-MONEY OPTIONS
                                                                            AT FY-END (#)        AT FY-END ($)(2)
                                        SHARES                          ---------------------  --------------------
                                     ACQUIRED ON          VALUE             EXERCISABLE/           EXERCISABLE/
NAME                                 EXERCISE (#)    REALIZED ($)(1)        UNEXERCISABLE         UNEXERCISABLE
- -----------------------------------  ------------  -------------------  ---------------------  --------------------
<S>                                  <C>           <C>                  <C>                    <C>
Gordon M. Binder...................          -0-                -0-             682,712/              28,467,209/
                                                                                321,430               11,001,445
Kevin W. Sharer....................          -0-                -0-              20,000/                     -0-/
                                                                                200,200                  956,475
Daniel Vapnek......................       13,200            537,717             295,625/              12,673,650/
                                                                                 73,334                1,868,291
N. Kirby Alton.....................       39,594          1,456,787               7,400/                  11,250/
                                                                                 99,464                2,751,718
Lowell E. Sears....................       28,300          1,033,288              22,370/                 560,780/
                                                                                 74,190                1,738,358
<FN>
- ------------------------
(1)   Value  realized is based on the market value of the Company's Common Stock
      on the date of exercise, minus the exercise price and does not necessarily
      indicate that the optionee sold such stock.
(2)   Value of  unexercised  in-the-money options  is  calculated based  on  the
      market  value of the underlying securities,  minus the exercise price, and
      assumes sale of the underlying securities on December 31, 1993 at the then
      current market value of $49.50 per share.
</TABLE>

                                       12
<PAGE>
COMPENSATION COMMITTEE REPORT(1)

    The Board of Directors  has delegated to the  Compensation Committee of  the
Board of Directors (the "Compensation Committee") the authority to establish and
maintain  the  Job  Grade  and  Compensation  Range  Tables  and  Merit Increase
Guidelines both  used  to establish  initial  salary guidelines  and  merit  pay
increases   throughout  the  Company  and  as  the  basis  for  making  specific
recommendations to the Board concerning  the compensation of senior officers  of
the  Company, including the Chief Executive Officer of the Company. In addition,
the Compensation Committee  administers the Management  Incentive Plan  ("MIP"),
the  Option Plans, the Retirement and  Savings Plan, the Employee Stock Purchase
Plan and all other compensation and  benefit programs currently in place at  the
Company. Compensation Committee members are all non-employee directors.

    The  Omnibus Budget Reconciliation  Act of 1993 placed  a one million dollar
limit on the amount  of non-performance based  compensation for Named  Executive
Officers  that may be deducted by the Company for tax purposes. The Compensation
Committee intends to design and administer its compensation plans to support the
achievement of  the  Company's long-term  strategic  objectives and  to  enhance
stockholder  value and, to the extent possible, to maximize the deductibility of
compensation expense for tax purposes. The Committee has been advised that  upon
approval  by  the Company's  stockholders  of Proposal  2,  the MIP  will  be in
compliance with the  compensation deduction provisions  of the Internal  Revenue
Code. In this connection, the Board of Directors is seeking stockholder approval
of the material terms of the performance based MIP.

    The  method  used  by  the  Compensation  Committee  to  determine executive
compensation is designed to  provide for a base  salary that, while  competitive
with comparable companies, is nevertheless calculated to result in a base salary
that  is at  the lower end  of the  competitive range for  those companies. Base
salary is supplemented  by two  additional compensation  components: first,  the
MIP,   designed  to   reward  participants   for  individual   and  Company-wide
performance; and  second,  the  Company's  Option  Plans,  designed  to  provide
long-term  incentives to all employees of  the Company. Each of these components
is discussed in turn below:

BASE SALARY

    Base Salaries  for  all  employees,  including  executive  officers  of  the
Company, are determined based on an established Job Grade and Compensation Range
Table  that is  designed to  provide a Base  Salary that  ensures that salaries,
while remaining competitive with comparable companies,  are at the lower end  of
the  range for executive officers  and at the middle of  the range for all other
employees of the companies surveyed. In  monitoring the Executive Job Grade  and
Compensation  Range Table,  the members  of the  Compensation Committee compared
compensation   information   derived   from   compensation   surveys   outlining
compensation levels at major pharmaceutical companies, the majority of which are
included  in the Standard  & Poor's Drug  Index, leading biotechnology companies
and other high  technology companies.(2) Adjustments  to each individual's  Base
Salary  are made in  connection with annual performance  reviews. The amounts of
such increases are calculated using compensation levels at comparable  companies
and  the Merit Increase Guidelines which provide for percentage salary increases
based on  the  position  in  the  Compensation Range  and  the  result  of  each
individual's
- ------------------------
(1) The  material in this report and in  the performance graph is not soliciting
    material, is  not deemed  filed with  the SEC,  and is  not incorporated  by
    reference  in any filing of the Company under the Securities Act of 1933, as
    amended, or the Securities  Exchange Act of 1934,  as amended, whether  made
    before  or after the  date of this  proxy statement and  irrespective of any
    general incorporation language in such filing.
(2) The  Compensation  Committee  utilizes   data  and  summaries  provided   by
    Organization  Resources Counselors, Inc. and  Towers Perrin, two independent
    consulting  firms,  to  determine  comparable  companies,  including   major
    pharmaceutical,  leading biotechnology and  other high technology companies,
    and their compensation levels.

                                       13
<PAGE>
annual performance  review. The  recommended percentage  increases are  adjusted
annually  and  reflect the  Compensation  Committee's assessment  of appropriate
salary adjustments given the results of competitive surveys and general economic
conditions.

MANAGEMENT INCENTIVE PLAN

    The MIP has been established to reward participants for their  contributions
to  the achievement of Company-wide performance goals. All executive officers of
the Company and certain other key  employees, as determined by the  Compensation
Committee,  participate  in the  MIP.  MIP payouts  are  established at  a level
designed to ensure  that when  such payouts are  added to  a participant's  Base
Salary, the resultant compensation for above average performance will exceed the
average compensation level of comparable companies.

    The structure of the MIP provides for the development of a compensation pool
(the "Pool"). Amounts attributable to the Pool are based upon the achievement of
certain  specified performance  goals and  milestones established  by members of
management and approved by the Compensation  Committee at the beginning of  each
MIP  period. The plan  requires that at  least 50% of  the Pool determination be
based upon Return on Capital Employed  ("ROCE") and Growth in Revenue, with  the
remainder based upon two or three major goals selected by the Committee from the
goals established by management in connection with the planning process. The MIP
provides for a range of payouts based on actual achievements, with both the size
of  the Pool and the individual awards subject to an upside potential of 150% of
applicable targets  for the  achievement of  performance that  is  significantly
above  the target levels. No awards are  made to the participants, regardless of
the performance  achieved on  the  other goals  or by  individual  participants,
unless either the ROCE or the Growth in Revenue goal is achieved.

    At the beginning of each MIP period, participants in the MIP are required to
identify  individual performance objectives that  will contribute to the success
of the Company. Each participant's  payout from the MIP  Pool is based upon  the
respective   supervisor's  and   the  Compensation   Committee's  assessment  of
achievement of the participant's goals.  Performance objectives are stated as  a
range  of possible measured achievements.  In order to be  eligible to receive a
payout from the MIP, each individual  participant must have achieved his or  her
individual performance objectives at least at the minimum threshold. The minimum
threshold represents significant, but less than planned, performance. The payout
at  the minimum  threshold is  usually 50% of  the target  payout, assuming Pool
goals are achieved at target. The maximum amount payable to any participant  may
not exceed $900,000.

    The  Pool goals for  the MIP period  ended December 31,  1993 included goals
related to return on capital employed; growth in total revenue; specific product
development objectives; sales of EPOGEN-R- and NEUPOGEN-R-; and construction  of
a  new plant in  Puerto Rico. The  relative weightings of  these five factors in
determining the total Pool were 35%, 15%, 25%, 15% and 10%, respectively.  Based
upon  evaluations by management and approved  by the Compensation Committee, the
Company achieved 122% of the target Pool goals established under the MIP for the
period ended December 31, 1993.

OPTION PLANS

    The Option Plans offered by the Company have been established to provide all
employees of the Company with an  opportunity to share, along with  stockholders
of the Company, in the long-term performance of the Company.

    Periodic grants of stock options are generally made annually to all eligible
employees,   with  additional  grants  being  made  to  certain  employees  upon
commencement of employment and occasionally,  following a significant change  in
job  responsibility, scope  or title  or a  particularly noteworthy achievement.
Stock options granted  under the  various stock  option plans  generally have  a
three-,  four-or five-year  vesting schedule and  generally expire  seven or ten
years from the date of  grant. The exercise price  of options granted under  the
stock option plans are usually 100% of fair market value of the underlying stock
on the date of grant.

                                       14
<PAGE>
    Guidelines  for  the number  of stock  options for  each participant  in the
periodic grant program generally  are determined by  a procedure established  by
the Compensation Committee based upon several factors including the salary grade
midpoint,  the performance of each participant  and the approximate market price
of the stock at the  time of grant. The size  of the grants, as developed  under
the  procedure,  are  targeted to  be  somewhat  above competitive  levels  as a
reflection of both  the added  incentive to continue  the favorable  competitive
performance of the Company, as well as the risk attached to the future growth of
the biotech industry.

CEO COMPENSATION

    Mr.  Binder's  Base Salary,  MIP  payout and  grants  of stock  options were
determined in  accordance with  the  criteria described  in the  "Base  Salary",
"Management Incentive Plan" and "Option Plans" sections of this report. The Base
Salary  of Mr. Binder was set  at $475,008 as of March  1, 1993 and reflects the
Board's assessment of  his very favorable  performance and his  position in  the
Grade and Range Table.

    The MIP target for Mr. Binder for the MIP period ended December 31, 1993 was
set  at 78% of  Base Salary. The actual  award under the MIP  for the MIP period
ended December 31, 1993 was $487,057, or  104% of Base Salary. Payments made  to
Mr.  Binder as a participant  in the MIP for the  period ended December 31, 1993
reflect both  the Company's  level of  achievement  of the  Pool goals  and  Mr.
Binder's  level of  achievement of  his individual  performance objectives which
included the Company's Pool  goals of ROCE,  product development objectives  and
sales  of EPOGEN-R- and NEUPOGEN-R-. As previously discussed, no awards are made
to MIP participants  unless the Company  achieves either the  ROCE or Growth  in
Revenue goal.

    The  periodic stock option  grant to Mr.  Binder in July  1993 of options to
purchase 24,390 shares of  Common Stock of  the Company at  100% of fair  market
value  on the  date of grant,  or $35.875  per share, also  reflects the Board's
assessment of the substantial contributions made by Mr. Binder to the growth and
performance of the Company.

                COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS

<TABLE>
                 <S>                            <C>
                 Bernard H. Semler, Chairman    Steven Lazarus
                 Raymond F. Baddour             Edward J. Ledder
</TABLE>

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

    As noted above, as of March  28, 1994, the Company's Compensation  Committee
consisted  of Messrs.  Semler, Lazarus,  Ledder and  Dr. Baddour.  Dr. George B.
Rathmann, who chose not to stand for re-election as a director of the Company at
the 1993 Annual Meeting,  was a member of  the Compensation Committee until  May
19, 1993 and was an executive officer of the Company from 1980 to 1990.

                                       15
<PAGE>
PERFORMANCE MEASUREMENT COMPARISON

    The  chart  set forth  below shows  the value  of an  investment of  $100 on
December 31, 1988 in each of Amgen  stock, the Standard & Poor's 500 Index  (the
"S&P  500"), the Standard  & Poor's Drug  Index (the "S&P  Drug") and the NASDAQ
Pharmaceutical  Index   (the  "NASDAQ   Pharmaceutical").  All   values   assume
reinvestment of the pre-tax value of dividends and are calculated as of December
31 of each year.

     AMGEN STOCK PRICE VS. S&P 500, S&P DRUG, NASDAQ PHARMACEUTICAL INDEXES

<TABLE>
<CAPTION>
                                                                 NASDAQ
                         AMGEN       S&P 500     S&P DRUG    PHARMACEUTICAL
                       ----------   ---------   ----------   --------------
<S>                    <C>          <C>         <C>          <C>
12/31/88............   100.00       100.00      100.00          100.00
1/31/89.............   111.72       107.32      108.92          107.06
2/28/89.............   111.72       104.65      105.97          106.76
3/31/89.............   121.31       107.09      111.90          112.07
4/28/89.............   118.47       112.65      118.47          112.93
5/31/89.............   118.83       117.21      121.85          115.77
6/30/89.............   128.06       116.54      117.65          112.20
7/31/89.............   128.77       127.07      138.74          119.51
8/31/89.............   115.45       129.55      139.58          120.87
9/29/89.............   124.33       129.02      141.46          127.92
10/31/89............   170.16       126.03      142.27          128.19
11/30/89............   165.72       128.60      150.07          129.69
12/31/89............   145.12       131.69      149.75          125.90
1/31/90.............   138.37       122.84      140.52          114.45
2/28/90.............   170.16       124.43      133.04          123.77
3/30/90.............   182.77       127.72      139.95          127.72
4/30/90.............   189.52       124.54      141.32          125.60
5/31/90.............   207.64       136.68      162.80          139.77
6/29/90.............   230.02       135.76      168.70          146.60
7/31/90.............   255.42       135.32      176.27          143.88
8/31/90.............   267.85       123.09      162.40          129.96
9/28/90.............   263.23       117.10      153.39          123.66
10/31/90............   279.75       117.05      153.77          123.47
11/30/90............   343.34       124.62      169.51          143.42
12/31/90............   368.56       128.09      171.34          151.01
1/31/91.............   436.59       133.67      179.18          174.01
2/28/91.............   540.32       143.23      199.26          214.28
3/29/91.............   777.09       146.70      203.52          252.04
4/30/91.............   750.44       147.05      204.11          237.24
5/31/91.............   723.80       153.39      218.48          247.22
6/28/91.............   697.87       146.36      208.26          234.06
7/31/91.............   876.20       153.18      228.27          265.68
8/30/91.............   945.83       156.81      236.67          293.93
9/30/91.............   981.35       154.19      235.64          323.19
10/31/91............   1,065.72     156.26      245.87          370.22
11/29/91............   994.67       149.97      242.84          331.07
12/31/91............   1,345.47     167.12      282.33          401.34
1/31/92.............   1,252.22     164.00      263.68          418.89
2/28/92.............   981.35       166.13      263.51          382.61
3/31/92.............   1,110.12     162.90      247.04          347.53
4/30/92.............   994.67       167.68      244.30          290.62
5/29/92.............   1,083.48     168.50      245.04          301.45
6/30/92.............   1,081.35     165.99      239.14          291.22
7/31/92.............   1,163.41     172.77      255.40          306.99
8/31/92.............   1,125.75     169.24      243.02          279.45
9/30/92.............   1,114.56     171.22      226.15          274.24
10/30/92............   1,185.61     171.82      226.06          292.75
11/30/92............   1,363.23     177.67      231.76          337.65
12/31/92............   1,254.53     179.85      223.91          334.30
1/29/93.............   1,101.24     181.35      207.35          310.72
2/26/93.............   643.87       183.82      193.74          238.49
3/31/93.............   670.52       187.70      189.82          240.70
4/30/93.............   710.48       183.16      200.21          243.18
5/28/93.............   630.55       188.06      207.99          253.12
6/30/93.............   648.31       188.61      198.57          253.58
7/30/93.............   621.67       187.86      176.99          246.33
8/31/93.............   657.19       194.98      183.71          259.47
9/30/93.............   686.06       194.83      182.67          274.95
10/29/93............   810.39       198.86      192.76          299.52
11/30/93............   803.73       198.67      201.86          293.07
12/31/93............   879.22       201.08      204.90          301.30
</TABLE>

<TABLE>
<CAPTION>
                                         12/31/88   12/31/89   12/31/90    12/31/91     12/31/92    12/31/93
                                         ---------  ---------  ---------  -----------  -----------  ---------
<S>                                      <C>        <C>        <C>        <C>          <C>          <C>
Amgen..................................  $  100.00  $  145.12  $  368.56  $  1,345.47  $  1,254.53  $  879.22
S&P 500................................  $  100.00  $  131.69  $  128.09  $    167.12  $    179.85  $  201.08
S&P Drug...............................  $  100.00  $  149.75  $  171.34  $    282.33  $    223.91  $  204.90
NASDAQ Pharmaceutical..................  $  100.00  $  125.90  $  151.01  $    401.34  $    334.30  $  301.30
</TABLE>

                                       16
<PAGE>
                              CERTAIN TRANSACTIONS

    During  the fiscal year  ended December 31, 1993,  the Company had aggregate
loans outstanding in the original principal amounts of $158,000 to Mr. Larry  A.
May  and $200,000  to Mr.  Sharer, both  of whom  are executive  officers of the
Company. Each such loan is evidenced by a full recourse promissory note  secured
by  real estate  valued in  excess of  the principal  balance of  such loan. The
purpose of the loans was to provide  sufficient cash to each of Messrs. May  and
Sharer  to enable these key officers  to satisfy certain personal objectives and
obligations. The annual  interest rate  on each such  loan was  5.1% during  the
fiscal year ended December 31, 1993 and was 4.1% on February 28, 1994. Including
principal and accrued interest, the largest aggregate indebtedness since January
1,  1993 of Messrs. May  and Sharer under such  loans was $164,715 and $200,000,
respectively. The aggregate  outstanding indebtedness  at February  28, 1994  of
Messrs. May and Sharer under such loans was $158,000 and $200,000, respectively.

    In  January 1994,  Mr. Sears  entered into  a separation  agreement with the
Company. Mr. Sears resigned effective January 7, 1994 as Senior Vice  President,
Asia-Pacific,  and pursuant to  the separation agreement,  will resign effective
March 31, 1994 as Senior Vice  President and Acting Chief Financial Officer  and
from all other offices he holds with the Company or any of its subsidiaries. Mr.
Sears  may elect to extend the effective date of his resignation as Acting Chief
Financial Officer by the number of his accrued and unused vacation days.

    From the effective date of Mr. Sears' resignation through November 1994, the
Company will  pay  Mr.  Sears  a monthly  severance  payment  of  $19,250,  less
applicable  withholdings; however,  if Mr. Sears  commences full-time employment
with another employer, such severance payments will cease as of the date of such
employment. Pursuant to the terms of  the agreement, Mr. Sears received  payment
of  the full amount of the bonus payable  to him under the Company's MIP for the
fiscal year ended December 31, 1993, but will not be eligible for a bonus  under
such  plan for the period ending December 31, 1994. The Company will provide Mr.
Sears with medical, vision and dental insurance benefits through the earlier  of
November  30, 1994 or  the commencement of Mr.  Sears' full-time employment with
another employer. The Company also  agreed to transfer certain office  equipment
to Mr. Sears.

    In  connection with  his resignation,  Mr. Sears  agreed to  provide certain
consulting services  to the  Company from  the date  of the  termination of  his
employment  through March 31, 1995. In consideration for his consulting services
and a noncompetition agreement,  stock options previously  granted to Mr.  Sears
shall  continue to vest through  September 30, 1994. If he  elects to do so, Mr.
Sears must exercise all of his vested options no later than March 31, 1995.

               COMPLIANCE WITH SECTION 16(A) OF THE EXCHANGE ACT

    Section 16(a)  of  the Exchange  Act  requires the  Company's  officers  and
directors,  and  persons who  own more  than 10%  of a  registered class  of the
Company's equity  securities,  to  file  reports of  ownership  and  changes  in
ownership  with the SEC and with the National Association of Securities Dealers,
Inc. Officers, directors and greater than  10% stockholders are required by  SEC
regulation to furnish the Company with copies of all forms they file pursuant to
Section 16(a).

    Based  solely on its review  of the copies of such  forms received by it, or
written  representations  from  certain  reporting  persons  that  no  Forms   5
disclosing  delinquently reported transactions were  required for those persons,
the Company believes that, during the  fiscal year ended December 31, 1993,  all
filing  requirements applicable to its officers,  directors and greater than 10%
beneficial owners were complied  with, except that Dr.  Vapnek failed to  timely
report  one transaction, but did  report the transaction on  his fiscal year end
report on Form 5, which was timely filed. Additionally, one report covering  one
transaction  was filed late by PaineWebber  R&D Partners, L.P., a 10% beneficial
owner of the Company's contractual contingent payment rights.

                                       17
<PAGE>
                                 OTHER BUSINESS

    The Board of Directors knows of no other business that will be presented for
consideration at  the Annual  Meeting.  If other  matters are  properly  brought
before the meeting, it is the intention of the persons named in the accompanying
proxy  to vote the shares represented thereby on such matters in accordance with
their best judgment.

                                          By Order of the Board of Directors

                                                    [SIG]

                                          THOMAS E. WORKMAN, JR.
                                          SECRETARY

March 28, 1994

                                       18
<PAGE>
                             APPENDIX A

   The graphic shows the value of an investment of $100 on December 31, 1988
in each of Amgen Stock, the Standard & Poor's 500 Index (the "S&P 500"), the
Standard & Poor's Drug Index (the "S&P Drug") and the NASDAQ Pharmaceutical
Index (the "NASDAQ Pharmaceutical"). All values assume reinvestment of the
pre-tax value of dividends and are calculated as of December 31 of each year.






<PAGE>
                             APPENDIX B

                                                                  NO POSTAGE
                                                                   NECESSARY
                                                                   IF MAILED
                                                                    IN THE
                                                                 UNITED STATES

             -----------------------------------------------------
             |                BUSINESS REPLY MAIL                 |
             | FIRST CLASS MAIL  PERMIT NO. 67  Thousand Oaks, CA |
             -----------------------------------------------------

                    POSTAGE WILL BE PAID BY ADDRESSEE

                    Amgen Inc.
                    ATTN: Secretary, Mail Stop 10-2-E-400
                    1840 Dehavilland Drive
                    Thousand Oaks, CA 91320-1789


<PAGE>
Amgen Inc.

/ / I plan to attend the Annual Stockholders' Meeting on Tuesday, April 26,
1994.

________________________________________________________________________________
Name                              (Please print)

________________________________________________________________________________
Address

_____________________________________________________________________(_______)__
City                                     State         Zip            Telephone
No.
<PAGE>
                                   APPENDIX C
                                   AMGEN INC.
       AMGEN CENTER, 1840 DEHAVILLAND DRIVE, THOUSAND OAKS, CA 91320-1789
                     PROXY SOLICITED BY BOARD OF DIRECTORS
             FOR THE ANNUAL MEETING OF STOCKHOLDERS-APRIL 26, 1994
    Gordon  M. Binder and Thomas  E. Workman, Jr., or  either of them, each with
the power of substitution and revocation, hereby are authorized to represent the
undersigned, with all powers which  the undersigned would possess if  personally
present, to vote the shares of Amgen Inc. Common Stock of the undersigned at the
Annual  Meeting of Stockholders of  Amgen Inc., to be  held at the Century Plaza
Hotel and Tower, 2025 Avenue of  the Stars, Los Angeles, California  90067-4696,
at  10:30 A.M., PDT,  on Tuesday, April  26, 1994, and  at any postponements and
adjournments of that meeting, with all powers that the undersigned would possess
if personally  present, upon  and in  respect of  the following  matters and  in
accordance  with the following instructions,  with discretionary authority as to
any and all other business that may properly come before the meeting.

    You are encouraged to specify your choices by marking the appropriate boxes,
SEE REVERSE  SIDE, but  you need  not mark  any boxes  if you  wish to  vote  in
accordance  with the Board of Directors'  recommendations. PLEASE MARK, SIGN AND
DATE THE REVERSE SIDE AND MAIL PROMPTLY IN THE ENCLOSED ENVELOPE.

                                       Change of Address:

                                       _________________________________________

                                       _________________________________________

                                       _________________________________________

                                       (If you have written in the above  space,
                                       please  mark the corresponding box on the
                                       reverse side of this card.)  [SEE REVERSE
                                       SIDE]

    PLEASE MARK, SIGN, DATE AND RETURN PROMPTLY USING THE ENCLOSED ENVELOPE.
<PAGE>
/X/ Please mark your votes as in this example.

    THIS PROXY WILL BE VOTED AS SPECIFIED OR, IF NO CHOICE IS SPECIFIED, WILL BE
VOTED FOR THE ELECTION OF THE NAMED NOMINEES, FOR APPROVAL OF THE MATERIAL TERMS
OF  THE  COMPANY'S   PERFORMANCE  BASED  MANAGEMENT   INCENTIVE  PLAN  AND   FOR
RATIFICATION  OF THE SELECTION OF  ERNST & YOUNG AS  THE INDEPENDENT AUDITORS OF
THE COMPANY FOR ITS FISCAL YEAR ENDING DECEMBER 31, 1994. THE BOARD OF DIRECTORS
RECOMMENDS A VOTE FOR ELECTION OF THE NOMINEES FOR DIRECTOR AND FOR PROPOSALS  2
AND 3.

<TABLE>
<S>   <C>                                                                <C>
1.    To elect three directors to hold office until the 1997 Annual Meeting of Stockholders.
/ /   FOR all nominees listed below (except as marked to the contrary    / /WITHHOLD AUTHORITY to
      below).                                                            vote for all nominees.
      NOMINEES: Raymond F. Baddour; Gordon M. Binder; Franklin P. Johnson, Jr.
      TO WITHHOLD AUTHORITY TO VOTE FOR ANY NOMINEE(S), WRITE SUCH NOMINEE(S)' NAME(S) BELOW:
      --------------------------------------------------------------------------------------------
      --------------------------------------------------------------------------------------------
2.    To approve the material terms of the Company's performance based Management Incentive Plan.
      /  /  FOR                             /  /  AGAINST                             /  / ABSTAIN
3.    To ratify the selection of Ernst & Young as independent auditors of the Company for its
      fiscal year ending December 31, 1994.
      / /  FOR                             /  /  AGAINST                             /  /  ABSTAIN
/ /   Please indicate if a change of address was given on the reverse side.
</TABLE>

             As  of the date hereof, the undersigned hereby acknowledges receipt
             of the Notice of  Annual Meeting of Stockholders  to be held  April
             26,  1994, the  accompanying Proxy  Statement and  the accompanying
             Annual Report of the Company for the fiscal year ended December 31,
             1993.

             SIGNATURE _________________________________________________________

             SIGNATURE _________________________________________________________

                         DATED ___________________________________________, 1994

             NOTE: Please sign exactly as your name appears hereon. If the stock
             is registered in  the names  of two  or more  persons, each  should
             sign.    Executors,   administrators,   trustees,   guardians   and
             attorneys-in-fact  should  add  their   titles.  If  signer  is   a
             corporation,  please  give  full  corporate name  and  have  a duly
             authorized officer sign, stating title. If signer is a partnership,
             please sign in partnership name by authorized person.
<PAGE>
                                   APPENDIX D
                        CONFIDENTIAL VOTING INSTRUCTIONS
                                   AMGEN INC.
       AMGEN CENTER, 1840 DEHAVILLAND DRIVE, THOUSAND OAKS, CA 91320-1789
                     PROXY SOLICITED BY BOARD OF DIRECTORS
             FOR THE ANNUAL MEETING OF STOCKHOLDERS-APRIL 26, 1994

TO: BANK OF AMERICA, NT & SA AS TRUSTEE UNDER THE
    AMGEN RETIREMENT AND SAVINGS PLAN

    I  hereby instruct the  Trustee to vote (in  person or by  proxy) all of the
shares of Amgen Inc. Common Stock which are credited to my account at the Annual
Meeting of Stockholders of Amgen Inc., to be held at the Century Plaza Hotel and
Tower, 2025 Avenue of  the Stars, Los Angeles,  California 90067-4696, at  10:30
A.M., PDT, on Tuesday, April 26, 1994, and at any postponements and adjournments
of  that meeting, upon and in respect of the following matters and in accordance
with the following instructions, with discretionary authority as to any and  all
other business that may properly come before the meeting.

    You are encouraged to specify your choices by marking the appropriate boxes,
SEE  REVERSE SIDE. PLEASE MARK, SIGN AND DATE THE REVERSE SIDE AND MAIL PROMPTLY
IN THE ENCLOSED ENVELOPE.

                                       Change of Address:

                                       _________________________________________

                                       _________________________________________

                                       _________________________________________
                                       (If you have written in the above  space,
                                       please  mark the corresponding box on the
                                       reverse side of this card.)  [SEE REVERSE
                                       SIDE]

    PLEASE MARK, SIGN, DATE AND RETURN PROMPTLY USING THE ENCLOSED ENVELOPE.
<PAGE>
/X/ Please mark your votes as in this example.

    THIS PROXY WILL BE VOTED AS SPECIFIED OR, IF NO CHOICE IS SPECIFIED, WILL BE
VOTED FOR THE ELECTION OF THE NAMED NOMINEES, FOR APPROVAL OF THE MATERIAL TERMS
OF  THE  COMPANY'S   PERFORMANCE  BASED  MANAGEMENT   INCENTIVE  PLAN  AND   FOR
RATIFICATION  OF THE SELECTION OF  ERNST & YOUNG AS  THE INDEPENDENT AUDITORS OF
THE COMPANY FOR ITS FISCAL YEAR ENDING DECEMBER 31, 1994.

<TABLE>
<C>        <S>                                                  <C>
       1.  To elect three directors to hold office until the 1997 Annual Meeting of Stockholders.
      / /  FOR all nominees listed below (except as marked to   / /WITHHOLD AUTHORITY to vote for all
           the contrary below).                                    nominees.
           NOMINEES: Raymond F. Baddour; Gordon M. Binder; Franklin P. Johnson, Jr.
           TO WITHHOLD AUTHORITY TO VOTE FOR ANY NOMINEE(S), WRITE SUCH NOMINEE(S)' NAME(S) BELOW:
           ------------------------------------------------------------------------------------------------
           ------------------------------------------------------------------------------------------------
       2.  To approve the material terms of the Company's performance based Management Incentive Plan.
           /  /  FOR                               /  /  AGAINST                               /  /   ABSTAIN
       3.  To ratify the selection of Ernst & Young as independent auditors of the Company for its fiscal
           year ending December 31, 1994.
           /   /  FOR                               /  /  AGAINST                               /  /  ABSTAIN
      / /  Please indicate if a change of address was given on the reverse side.
</TABLE>

             As of the date hereof, the undersigned hereby acknowledges  receipt
             of  the Notice of  Annual Meeting of Stockholders  to be held April
             26, 1994,  the accompanying  Proxy Statement  and the  accompanying
             Annual Report of the Company for the fiscal year ended December 31,
             1993.

             SIGNATURE _________________________________________________________

             SIGNATURE _________________________________________________________

                         DATED ___________________________________________, 1994

             NOTE: Please sign exactly as your name appears hereon. If the stock
             is  registered in  the names  of two  or more  persons, each should
             sign.   Executors,   administrators,   trustees,   guardians    and
             attorneys-in-fact   should  add  their  titles.   If  signer  is  a
             corporation, please  give  full  corporate name  and  have  a  duly
             authorized officer sign, stating title. If signer is a partnership,
             please sign in partnership name by authorized person.
<PAGE>
                                   APPENDIX E
                        CONFIDENTIAL VOTING INSTRUCTIONS
                                   AMGEN INC.
       AMGEN CENTER, 1840 DEHAVILLAND DRIVE, THOUSAND OAKS, CA 91320-1789
                     PROXY SOLICITED BY BOARD OF DIRECTORS
             FOR THE ANNUAL MEETING OF STOCKHOLDERS-APRIL 26, 1994

    You are encouraged to specify your choices by marking the appropriate boxes,
SEE  REVERSE  SIDE, but  you need  not mark  any boxes  if you  wish to  vote in
accordance with the Board of  Directors' recommendations. PLEASE MARK, SIGN  AND
DATE THE REVERSE SIDE AND MAIL PROMPTLY IN THE ENCLOSED ENVELOPE.

TO: BANCO SANTANDER PUERTO RICO AS TRUSTEE UNDER THE
    RETIREMENT AND SAVINGS PLAN FOR AMGEN MANUFACTURING, INC.

    I  hereby instruct the  Trustee to vote (in  person or by  proxy) all of the
shares of Amgen Inc. Common Stock which are credited to my account at the Annual
Meeting of Stockholders of Amgen Inc., to be held at the Century Plaza Hotel and
Tower, 2025 Avenue of  the Stars, Los Angeles,  California 90067-4696, at  10:30
A.M., PDT, on Tuesday, April 26, 1994, and at any postponements and adjournments
of  that meeting, upon and in respect of the following matters and in accordance
with the following instructions, with discretionary authority as to any and  all
other business that may properly come before the meeting.

                                       Change of Address:
                                       _________________________________________

                                       _________________________________________

                                       _________________________________________
                                       (If  you have written in the above space,
                                       please mark the corresponding box on  the
                                       reverse side of this card.)  [SEE REVERSE
                                       SIDE]

    PLEASE MARK, SIGN, DATE AND RETURN PROMPTLY USING THE ENCLOSED ENVELOPE.
<PAGE>
/X/ Please mark your votes as in this example.

    THIS PROXY WILL BE VOTED AS SPECIFIED OR, IF NO CHOICE IS SPECIFIED, WILL BE
VOTED FOR THE ELECTION OF THE NAMED NOMINEES, FOR APPROVAL OF THE MATERIAL TERMS
OF THE COMPANY'S PERFORMANCE BASED MANAGEMENT INCENTIVE PLAN AND FOR
RATIFICATION OF THE SELECTION OF ERNST & YOUNG AS THE INDEPENDENT AUDITORS OF
THE COMPANY FOR ITS FISCAL YEAR ENDING DECEMBER 31, 1994. THE BOARD OF DIRECTORS
RECOMMENDS A VOTE FOR ELECTION OF THE NOMINEES FOR DIRECTOR AND FOR PROPOSALS 2
AND 3.

<TABLE>
<C>        <S>                                                  <C>
       1.  To elect three directors to hold office until the 1997 Annual Meeting of Stockholders.
      / /  FOR all nominees listed below (except as marked to   / /WITHHOLD AUTHORITY to vote for all
           the contrary below).                                    nominees.
           NOMINEES: Raymond F. Baddour; Gordon M. Binder; Franklin P. Johnson, Jr.
           TO WITHHOLD AUTHORITY TO VOTE FOR ANY NOMINEE(S), WRITE SUCH NOMINEE(S)' NAME(S) BELOW:
           ------------------------------------------------------------------------------------------------
           ------------------------------------------------------------------------------------------------
       2.  To approve the material terms of the Company's performance based Management Incentive Plan.
           /   /  FOR                               /  /  AGAINST                               /  /  ABSTAIN
       3.  To ratify the selection of Ernst & Young as independent auditors of the Company for its fiscal
           year ending December 31, 1994.
           /  /  FOR                               /  /  AGAINST                               /  /   ABSTAIN
      / /  Please indicate if a change of address was given on the reverse side.
</TABLE>

             As  of the date hereof, the undersigned hereby acknowledges receipt
             of the Notice of  Annual Meeting of Stockholders  to be held  April
             26,  1994, the  accompanying Proxy  Statement and  the accompanying
             Annual Report of the Company for the fiscal year ended December 31,
             1993.

             SIGNATURE _________________________________________________________

             SIGNATURE _________________________________________________________

                         DATED ___________________________________________, 1994

             NOTE: Please sign exactly as your name appears hereon. If the stock
             is registered in  the names  of two  or more  persons, each  should
             sign.    Executors,   administrators,   trustees,   guardians   and
             attorneys-in-fact  should  add  their   titles.  If  signer  is   a
             corporation,  please  give  full  corporate name  and  have  a duly
             authorized officer sign, stating title. If signer is a partnership,
             please sign in partnership name by authorized person.
<PAGE>
                                   APPENDIX F

MEMORANDUM

To:       All Employees Holding Amgen Inc. Common Stock
          Through Participation in the Amgen Retirement and Savings Plan
          --------------------------------------------------------

From:     Sarah E. Clark

Date:     March 28, 1994

Subj:     Amgen Inc. - 1994 Proxy Material

As you know, you have allocated a portion of your Amgen Retirement and Savings
Plan (the "Plan") contributions toward purchasing shares of Common Stock of
Amgen Inc. ("Amgen" or the  "Company").  Pursuant to the terms of the Plan
as amended, you are entitled to vote on the proposals to be presented at the
1994 Annual Stockholders' Meeting (the "Meeting") based on the number of shares
of the Company's Common Stock that were allocated to your Plan account as of
January 31, 1994.  Enclosed with this memorandum are the Company's 1993 Annual
Report, the Notice of  Annual Meeting of Stockholders and accompanying Proxy
Statement of the Company, that outlines the proposals  to be presented at the
Meeting, a blue proxy card and a return envelope for your proxy card.

PLEASE NOTE THAT YOUR VOTING WITH RESPECT TO THE COMMON STOCK IN YOUR PLAN
ACCOUNT IS HELD IN THE STRICTEST  CONFIDENCE.  No officer or employee of the
Company has the right to review your completed Plan proxy card.   THEREFORE, IN
ORDER FOR YOUR VOTES TO BE COUNTED, YOU MUST RETURN YOUR COMPLETED PLAN PROXY
CARD TO  AMERICAN STOCK TRANSFER & TRUST COMPANY ("ASTTC") IN THE ENVELOPE
PROVIDED.  If you return your  completed Plan proxy card to any officer or
employee of the Company, your votes cannot be counted.

You are entitled to vote with respect to the number of shares held in your Plan
account.  Such number of shares can  be found to the left of your name and
address on the enclosed proxy card.  It is extremely important that you vote,
sign, date and PROMPTLY mail the enclosed blue Plan proxy card to ASTTC in the
enclosed, self-addressed, stamped envelope at your earliest convenience.
If ASTTC does not receive your completed Plan  proxy card in a timely fashion,
the Plan Trustee,  Bank of America, NT&SA, will vote your shares in
accordance with the voting instructions that have been  received from other
Plan participants.

If you held additional Common Stock of the Company as of the
record date for the Meeting in certificate form or  through your bank or
broker, you will receive additional proxy cards for those shares.  In order
for all of your  shares to be voted, you should complete and return promptly
each proxy card that you receive.

If you have any questions regarding this memorandum or the enclosures, please
call me at Extension 3896.  Thank  you for your prompt attention to this
matter.

Enclosures
<PAGE>
                           APPENDIX G

MEMORANDUM

To:       All Employees Holding Amgen Inc. Common Stock
          Through Participation in the Retirement and Savings Plan
          for Amgen Manufacturing, Inc.
          -------------------------------------------------------

From:     Sarah E. Clark

Date:     March 28, 1994

Subj:     Amgen Inc. - 1994 Proxy Material

As you know, you have allocated a portion of your Retirement and
Savings Plan for Amgen Manufacturing, Inc.  (the "Plan")
contributions toward purchasing shares of Common Stock of Amgen
Inc. ("Amgen" or the  "Company").  Pursuant to the terms of the
Plan, you are entitled to vote on the proposals to be presented
at the  1994 Annual Stockholders' Meeting (the "Meeting") based
on the number of shares of the Company's Common  Stock that were
allocated to your Plan account as of  December 31, 1993.
Enclosed with this memorandum are the Company's 1993 Annual
Report, the Notice of  Annual Meeting of Stockholders and
accompanying Proxy Statement of the Company, that outlines the
proposals  to be presented at the Meeting, a green proxy card and
a return envelope for your proxy card.

PLEASE NOTE THAT YOUR VOTING WITH RESPECT TO THE COMMON STOCK IN
YOUR PLAN ACCOUNT IS HELD IN THE STRICTEST  CONFIDENCE.  No
officer or employee of the Company has the right to review your
completed Plan proxy card.   THEREFORE, IN ORDER FOR YOUR VOTES
TO BE COUNTED, YOU MUST RETURN YOUR COMPLETED PLAN PROXY CARD TO
AMERICAN STOCK TRANSFER & TRUST COMPANY ("ASTTC") IN THE ENVELOPE
PROVIDED.  If you return your  completed Plan proxy card to any
officer or employee of the Company, your votes cannot be counted.

You are entitled to vote with respect to the number of shares
held in your Plan account.  Such number of shares can  be found
to the left of your name and address on the enclosed proxy card.
It is extremely important that you vote,  sign, date and PROMPTLY
mail the enclosed green Plan proxy card to ASTTC in the enclosed,
self-addressed, stamped envelope at your earliest convenience.
If ASTTC does not receive your completed Plan  proxy card in a
timely fashion, the Plan Trustee,  Banco Santander Puerto Rico,
will vote your shares in accordance with the voting instructions
that have been  received from other Plan participants.

If you held additional Common Stock of the Company as of the record date
for the Meeting in certificate form or  through your bank or
broker, you will receive additional proxy cards for those shares.
In order for all of your  shares to be voted, you should complete
and return promptly each proxy card that you receive.

If you have any questions regarding this memorandum or the
enclosures, please call me at (805) 447-3896.  Thank  you for
your prompt attention to this matter.

Enclosures
<PAGE>

                                   APPENDIX H


                                      AMGEN

                                PERFORMANCE BASED

                            MANAGEMENT INCENTIVE PLAN


<PAGE>

                                      AMGEN

                                PERFORMANCE BASED

                            MANAGEMENT INCENTIVE PLAN



I.   PURPOSE

     This Amgen Performance Based Management Incentive Plan (MIP) is established
     to:

     A.   Attract and retain persons of outstanding competence.

     B.   Broaden the total compensation program

     C.   Stimulate outstanding effort to bring about exceptional operating
          performance and to reward the contributors to this performance by
          providing them with a share of the resulting benefits.

     The Plan is intended to supplement the participant's base salary and
     result in total cash compensation for above average performance which
     exceeds the average compensation levels of comparable companies.

II.  BASIC CONCEPTS

     Since the purpose of this Management Incentive Plan is to stimulate and
     reward outstanding performance in the accomplishment of specific
     objectives, it necessarily follows that the plan must be formally
     integrated with the objectives of the total management system. The
     incentive plan should thus support a continuing and meaningful emphasis on
     the effective use of goal setting and management by objectives and be
     aligned with the goals reflected in the approved Annual Plan of the
     company.

     Annual plans shall be developed under the following basic concepts:

     A.   The advance identification of the participants in the plan and the
          establishment of specific performance objectives and the basis of
          participation for each.

     B.   The establishment of  a range in the actual awards available under the
          plan to reflect the achievements of the respective participants as
          well as the achievement of the financial and technical performance
          objectives reflected in the Company's approved Annual Plan.

III. ELIGIBILITY

     A.   Participation in the Amgen Management Incentive Plan shall be limited
          to all executive officers of the company and certain other key
          employees nominated by the Chairman of the Board and approved by the
          Compensation Committee of the Board of Directors.

     B.   Unless otherwise specifically authorized by the Compensation
          Committee, persons approved for participation in the Amgen Management
          Incentive Plan shall be excluded from participation in any other cash
          bonus or incentive program.

                                        1

<PAGE>


IV.  BASIS OF PARTICIPATION

     A.   Participants will share in the Incentive Plan on the basis of
          percentages established in advance - as recommended by the Chairman
          and approved by the Compensation Committee of the Board of Directors
          as part of the annual compensation plan.

     B.   The extent of participation for individuals in the plan shall be
          developed in accordance with the following:

          1.   In connection with the planning of their performance objectives
               for the MIP year, the Chairman shall recommend (for approval by
               the Compensation Committee) the individual participants, the
               extent of participation and the average overall target incentive
               (expressed as a % of the base pay of the participants) to be
               awarded for achieving the Plan objectives and all of the goals of
               the participants.

          2.   In establishing the overall target percentage of base pay of
               participants in B.1 (above), the level of participation for each
               participant (as a % of base pay) shall be established in
               accordance with guidelines established by the Compensation
               Committee.

               (a)  Because of the many variables in establishing base salary
                    structures, the plan does not contemplate achieving any
                    degree of uniformity in the relationship of awards to base
                    pay.  Therefore, target ranges will be rather broad.
                    Individual target participation should be based upon
                    consideration of:

                    (1)  Relative significance of the individual's function in
                         directly influencing the performance of the company.

                    (2)  Relative performance rating of the individual.

                    (3)  Length of time in position and/or Plan.  Generally, it
                         should be expected that initial percentages for new
                         participants will be set at levels which allow for
                         gradual increases within the established range based
                         upon participant's performance.

                    (4)  The relative competitive total compensation for the
                         respective position.

     C.   The overall target incentive (as established in accordance with
          IV.B.2) shall become the basis for establishing the "Target Pool" for
          achievement of the objectives detailed in the Plan, and be converted
          into a formula established by the Compensation Committee to reflect
          the key elements of Plan Performance.

          1.   The incentive formula shall provide for upward/downward
               adjustment of the target pool to reflect actual performance -
               with the upward adjustment, resulting from a very significant
               over-achievement of the key factors of performance measurement
               identified in the Plan, subject to a maximum established annually
               by the Compensation Committee, which in no event shall be more
               than 150% of the target pool.

                                        2

<PAGE>


IV.  BASIS OF PARTICIPATION (Continued)


     D.   The target incentive for each participant (as established in IV. B.)
          shall be converted into a percentage of the Target Pool.

          1.   Actual awards under the Plan shall be determined by applying the
               actual percentage earned by the participant to the actual
               incentive pool determined in accordance with IV.C. Thus, the
               final awards to participants are dependent upon two interrelated
               factors: (1) the availability of an incentive pool as a result of
               the overall company performance; (2) the achievements of the
               respective participants as measured by their own performance.

     E.   The participation for each individual shall be established in two
          parts as follows:

          1.   Basic - Not more than 35% of the total planned participation -
               with the award based upon achievement of the participants total
               performance goals and the evaluation of overall performance.

               (a)  In determining the final award, the basic percentage for a
                    participant may range from zero to being adjusted upward as
                    much as 50% from that established in the original plan in
                    recognition of outstanding overall performance - so long as
                    the total of the basic percentage participation of all
                    participants in the Plan does not exceed the total reflected
                    in the approved Plan.

               (b)  Since the specific goals (as established under E.2) should
                    identify major areas for current year emphasis, it should
                    follow that the degree of achievement against these specific
                    goals should also have a significant impact on the overall
                    performance of the individual under the basic participation.
                    Thus, it should be very unlikely that a participant who
                    failed significantly to accomplish specific goals would be
                    rated at or above target in connection with the basic
                    performance evaluation.

          2.   Specific - At least 65% of the total planned participation should
               be identified with specific goals relating to the performance of
               the respective participants.

               (a)  Specific goals should number at least 4 and generally not
                    more than 6. They should be selected from the total
                    performance goals and relate to significant and measurable
                    areas that require special attention during the current
                    year. The purpose is to add special emphasis to those
                    particular activities and reward for their accomplishments
                    without, however, placing undue emphasis on these particular
                    objectives vs. the overall job performance. From year-to-
                    year, it is expected that the emphasis will change, both in
                    relation to the selected goals as well as to the importance
                    of the percentage participation attached to them.


                                        3

<PAGE>


IV.  BASIS OF PARTICIPATION (Continued)

     E.   2.   (b)  Specific goals should be precise in establishing the targets
                    and the basis for measurement of accomplishment. Wherever
                    there can be variations in the degree of accomplishment
                    (such as a dollar target for total revenues or joint
                    ventures; a target for filing IND's or PLA's; etc.), the
                    range of percentage participation relating to the levels of
                    accomplishment should be clearly stated.

               (c)  Where specific goals relate to dollar objectives they should
                    be identified with or reconciled to amounts reflected in the
                    company's approved Annual Plan.

               (d)  Final award for a participant's specific goal achievement
                    may be adjusted upward by as much as 50% from the target
                    percentage included in the original plan, provided that:

                    1)   The performance reflects a substantial improvement over
                         amounts reflected in the original goal, as defined in
                         the ranges established under B. above.

               (e)  If operating conditions during the year make it desirable to
                    change emphasis on established goals or to establish new
                    goals, a revised plan should be submitted with the same
                    approvals as for the original Plan.

V.   ADMINISTRATION

     A.   The overall administration of this Management Incentive Plan shall be
          under the direction of the Compensation Committee of the Board of
          Directors.

     B.   Responsibility for the operating administration of the Plan shall be
          under the direction of the company's Vice President of Human
          Resources.

VI.  DETERMINATION OF AWARDS

     A.   Promptly following the close of the Plan year, the respective managers
          shall evaluate the performance of the participants, determine the
          amount of recommended awards (in terms of % achievement) and forward
          for review and approval. In all cases the recommended award shall be
          determined only after a self-assessment has been completed.

     B.   The final determination of the Incentive Pool will be made by the
          Compensation Committee, promptly following the availability of year-
          end financial and technical results.

     C.   Dollar awards to participants will be computed by applying the percent
          achievement determined in accordance with A. above to the final pool
          determined in accordance with B. above subject to the limitation that
          the maximum amount payable to any participant may not exceed $900,000.


                                        4

<PAGE>


VII. PAYMENTS, TERMINATION OF EMPLOYMENT AND GENERAL CONDITIONS

     A.   Payments to participants who have been determined to be entitled to an
          award will be made in cash generally not later than sixty (60) days
          following the close of the Fiscal Year.

     B.   If a participant dies or employment is terminated for any reason prior
          to the end of the Plan year, the payment of any award (and in the case
          of death, the person or persons to whom such payment shall be made)
          shall be determined at the sole discretion of the Committee.

     C.   While it is the intent of the company to continue such Plan during any
          year for which it is established and to make awards to participants in
          accordance with these policies and guidelines, the company reserves
          the right to amend, modify or terminate any Plan, or any participant's
          participation in such plan at any time or on such conditions as the
          Compensation Committee shall deem appropriate. No participant shall
          have any right to any award under the Plan until such award and the
          amount thereof has been finally approved by the Compensation Committee
          and communicated to such participant after the end of the year for
          which the award is being made.


                                        5
MARCH 23, 1994



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