AMGEN INC
10-Q/A, 1995-05-16
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                 SECURITIES AND EXCHANGE COMMISSION

                        WASHINGTON D.C. 20549

                             FORM 10-Q/A



(Mark One)
[ X ]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
       SECURITIES EXCHANGE ACT OF 1934

     For the quarterly period ended March 31, 1995

                                 OR

[   ]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
       SECURITIES EXCHANGE ACT OF 1934


Commission file number 0-12477


                             AMGEN INC.
       (Exact name of registrant as specified in its charter)


          Delaware                                95-3540776
- -------------------------------         -----------------------------
(State or other jurisdiction of                (I.R.S. Employer
incorporation or organization)                Identification No.)


1840 Dehavilland Drive, Thousand Oaks, California     91320-1789
- ----------------------------------------------------------------------
    (Address of principal executive offices)          (Zip Code)


Registrant's telephone number, including area code:    (805) 447-1000


Indicate by  check mark  whether the  registrant  (1) has  filed  all
reports required to be filed by Section 13 or 15(d) of the Securities
Exchange Act of  1934 during the  preceding 12 months   (or for  such
shorter  period  that  the  registrant  was  required  to  file  such
reports), and (2) has  been subject to  such filing requirements  for
the past 90 days.                  Yes  X    No

     As of March 31, 1995, the  registrant had 132,344,322 shares  of
Common Stock, $.0001 par value, outstanding.
<PAGE>
                             AMGEN INC.

                                INDEX


                                                         Page No.

PART I    FINANCIAL INFORMATION

          Item 1.Financial Statements .......................3

            Condensed Consolidated Statements of
            Operations - three months
            ended March 31, 1995 and 1994 ...................4

            Condensed Consolidated Balance Sheets -
            March 31, 1995 and December 31, 1994 ............5

            Condensed Consolidated Statements of
            Cash Flows - three months
            ended March 31, 1995 and 1994 ...............6 - 7

            Notes to Condensed Consolidated Financial
            Statements ......................................8

          Item 2.Management's Discussion and Analysis
                 of Financial Condition and Results of
                 Operations ................................13


PART II   OTHER INFORMATION

          Item 1.Legal Proceedings .........................17

          Item 6.Exhibits and Reports on Form 8-K ..........20

          Signatures........................................21

          Index to Exhibits.................................22
<PAGE>
                   PART I - FINANCIAL INFORMATION


Item 1.   Financial Statements

     The information  in  this  report for  the  three  months  ended
March 31, 1995 and  1994 is  unaudited but  includes all  adjustments
(consisting only  of  normal  recurring accruals)  which  Amgen  Inc.
("Amgen"  or   the  "Company")   considers  necessary   for  a   fair
presentation of the results of operations for those periods.

     The condensed financial statements should be read in conjunction
with  the  Company's  financial  statements  and  the  notes  thereto
contained in the Company's Annual Report on Form 10-K for the  fiscal
year ended December 31, 1994.

     Interim results are  not necessarily indicative  of results  for
the full fiscal year.
<PAGE>
                             AMGEN INC.

           CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

                (In thousands, except per share data)
                             (Unaudited)

                                           Three Months Ended
                                               March 31,
                                           1995        1994
                                        ----------  ----------
    Revenues:
      Product sales.....................  $411,237    $345,731
      Corporate partner revenues........    19,776      13,991
      Royalty income....................     8,353       4,276
                                          --------    --------
         Total revenues.................   439,366     363,998
                                          --------    --------
    Operating expenses:
      Cost of sales.....................    66,573      53,283
      Research and development..........   113,883      73,725
      Marketing and selling.............    58,761      53,173

      General and administrative........    34,638      28,308
      Loss of affiliates, net...........    12,685       7,257
                                          --------    --------
         Total operating expenses.......   286,540     215,746
                                          --------    --------

    Operating income....................   152,826     148,252
                                          --------    --------
    Other income (expense):
      Interest and other income.........    12,899       5,511
      Interest expense, net.............    (3,784)     (2,640)
                                          --------    --------
    Total other income (expense)........     9,115       2,871
                                          --------    --------

    Income before income taxes..........   161,941     151,123

    Provision for income taxes..........    53,317      57,663
                                          --------    --------
    Net income..........................  $108,624    $ 93,460
                                          ========    ========

    Earnings per share:
      Primary earnings per share........     $0.78       $0.66
      Fully diluted earnings per share..     $0.78       $0.66

    Shares used in calculation of:
      Primary earnings per share........   139,752     141,371
      Fully diluted earnings per share..   140,131     141,371

                       See accompanying notes.
<PAGE>
                             AMGEN INC.

                CONDENSED CONSOLIDATED BALANCE SHEETS

                (In thousands, except per share data)
                             (Unaudited)

                                             March 31,  December 31,
                                               1995        1994
                                            ----------  ----------
                               ASSETS
Current assets:
 Cash and cash equivalents................. $  199,024  $  211,323
 Marketable securities.....................    568,359     485,358
 Trade receivables, net....................    189,128     194,712
 Inventories...............................     92,497      98,004
 Deferred tax assets, net..................     70,176      70,176
 Other current assets......................     49,746      56,065
                                            ----------  ----------
     Total current assets..................  1,168,930   1,115,638

Property, plant and equipment at cost, net.    670,596     665,314
Investments in affiliated companies........     75,745      82,263
Other assets...............................    137,140     130,932
                                            ----------  ----------
                                            $2,052,411  $1,994,147
                                            ==========  ==========

                LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
 Accounts payable.......................... $   33,451  $   30,476
 Commercial paper..........................     99,339      99,667
 Other accrued liabilities.................    401,153     406,287
                                            ----------  ----------
     Total current liabilities.............    533,943     536,430

Long-term debt.............................    181,205     183,407

Commitments and contingencies

Stockholders' equity:
 Common stock, $.0001 par value; 750,000
    shares authorized; outstanding -
    132,344 shares in 1995 and 132,328
    shares in 1994.........................         13          13
 Additional paid-in capital................    748,814     719,310
 Retained earnings.........................    588,436     554,987
                                            ----------  ----------
     Total stockholders' equity............  1,337,263   1,274,310
                                            ----------  ----------
                                            $2,052,411  $1,994,147
                                            ==========  ==========

                       See accompanying notes.
<PAGE>
                             AMGEN INC.

           CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

                           (In thousands)
                             (Unaudited)

                                            Three Months Ended
                                                 March 31,
                                              1995      1994
                                            --------  --------

     Cash flows from operating activities:
      Net income........................... $108,624  $ 93,460
      Depreciation and amortization........   19,719    17,846
      Deferred income taxes................        -     2,507
      Loss of affiliates, net..............   12,685     7,257
      Cash provided by (used in):
       Trade receivables, net..............    5,584    (6,783)
       Inventories.........................    5,507    (7,200)
       Other current assets................    6,319       767
       Accounts payable....................    2,975    (2,346)
       Accrued liabilities.................   (5,107)   11,172
                                            --------  --------
          Net cash provided by operating
            activities.....................  156,306   116,680
                                            --------  --------

     Cash flows from investing activities:
      Purchases of property, plant and
         equipment.........................  (24,965)  (36,978)
      Proceeds from maturities of
         marketable securities.............   35,323    19,000
      Proceeds from sales of marketable
         securities........................  303,190   587,390
      Purchases of marketable securities... (421,514) (584,044)
      Decrease in investments in
         affiliated companies..............    4,555       651
      Increase in other assets.............   (6,208)  (10,167)
                                            --------  --------
          Net cash used in investing
            activities..................... (109,619)  (24,148)
                                            --------  --------

                       See accompanying notes.

                      (Continued on next page)
<PAGE>
                             AMGEN INC.

     CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Continued)

                           (In thousands)
                             (Unaudited)

                                            Three Months Ended
                                                 March 31,
                                              1995      1994
                                            --------  --------

     Cash flows from financing activities:
      Decrease in commercial paper......... $   (328)  $(9,920)
      Proceeds from issuance of long-term
         debt..............................        -    10,000
      Repayment of long-term debt..........   (2,229)     (524)
      Net proceeds from issuance of common
         stock upon the exercise of stock
         options...........................   23,769     5,278
      Tax benefit related to stock options.    5,700     4,400
      Net proceeds from issuance common
         stock upon the exercise of
         warrants..........................        -       846
      Repurchases of common stock..........  (75,175)  (75,138)
      Other................................  (10,723)   (8,248)
                                            --------  --------
          Net cash used in financing
            activities.....................  (58,986)  (73,306)
                                            --------  --------
     (Decrease) increase in cash and cash
       equivalents.........................  (12,299)   19,226

     Cash and cash equivalents at
       beginning of period.................  211,323   128,505
                                            --------  --------
     Cash and cash equivalents at end of
       period.............................. $199,024  $147,731
                                            ========  ========

                       See accompanying notes.
<PAGE>
                             AMGEN INC.

        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

                           March 31, 1995


1.   Summary of significant accounting policies

  Business

     Amgen Inc. ("Amgen" or the "Company") is a global  biotechnology
company that develops,  manufactures and  markets human  therapeutics
based on advanced cellular and molecular biology.

  Principles of consolidation

     The consolidated financial  statements include  the accounts  of
the Company and its wholly owned  subsidiaries as well as  affiliated
companies for which the Company has a controlling financial  interest
and exercises  control over  their operations  ("majority  controlled
affiliates").  All  material intercompany  transactions and  balances
have been  eliminated in  consolidation.   Investments in  affiliated
companies which  are 50%  owned and/or  where the  Company  exercises
significant influence  over operations  are accounted  for using  the
equity method.  All other equity investments are accounted for  under
the cost  method.   The caption  "Loss of  affiliates, net"  includes
Amgen's equity in the operating  results of affiliated companies  and
the minority interest others hold in the operating results of Amgen's
majority controlled affiliates.

  Inventories

     Inventories are stated at the lower of cost or market.  Cost  is
determined in  a manner  which approximates  the first-in,  first-out
(FIFO) method.  Inventories are shown net of applicable reserves  and
allowances.  Inventories consist of the following (in thousands):

                                          March 31,  December 31,
                                            1995         1994
                                          -------      -------
       Raw materials....................  $11,167      $10,943
       Work in process..................   43,978       54,032
       Finished goods...................   37,352       33,029
                                          -------      -------
                                          $92,497      $98,004
                                          =======      =======
  Product sales

     Product sales consist of two products, EPOGEN(R) (Epoetin  alfa)
and NEUPOGEN(R) (Filgrastim).
<PAGE>
     As  a  result   of  an   agreement  between   Amgen  and   Ortho
Pharmaceutical  Corporation,  a  subsidiary  of  Johnson  &   Johnson
("Johnson &  Johnson") covering  the U.S.  market for  the  Company's
Epoetin alfa product, Amgen does not recognize product sales it makes
into the contractual market of Johnson  & Johnson and does  recognize
the product sales made by Johnson & Johnson into Amgen's  contractual
market.  These  sales amounts, and  adjustments thereto, are  derived
from third-party data on  shipments to end users  and their usage  as
the data becomes available  (see Note 4,  "Contingencies - Johnson  &
Johnson arbitration").

  Income taxes

     Income taxes are accounted for  in accordance with Statement  of
Financial Accounting Standards ("SFAS") No. 109 (Note 3).

  Earnings per share

     Earnings per share are computed in accordance with the  treasury
stock method.  Primary and fully diluted earnings per share are based
upon the weighted average number of common shares and dilutive common
stock equivalents during the period  in which they were  outstanding.
Common  stock  equivalents  include  outstanding  options  under  the
Company's stock option plans and warrants  to purchase shares of  the
Company's common stock.  The warrants expired on June 30, 1994.

  Basis of presentation

     The financial information for the  three months ended March  31,
1995 and 1994 is unaudited  but includes all adjustments  (consisting
only of  normal  recurring  accruals)  which  the  Company  considers
necessary for a fair  presentation of the  results of operations  for
these periods.   Interim results  are not  necessarily indicative  of
results for the full fiscal year.

  Reclassification

     Certain prior period amounts  have been reclassified to  conform
to the current period presentation.

2.   Debt

     As of  March 31,  1995, $99.3  million of  commercial paper  was
outstanding.  These borrowings had maturities of three months or less
and had effective interest rates averaging 6.1%.

     As of March  31, 1995, $150.0  million was  available under  the
Company's line of credit for borrowing  and to support the  Company's
commercial paper program.
<PAGE>
     Long-term debt consists of the following (in thousands):

                                           March 31,  December 31,
                                             1995         1994
                                           --------     --------
       Medium Term Notes.................  $113,000     $113,000
       Promissory notes..................    68,200       68,200
       Other long-term obligations.......        23        2,252
                                           --------     --------
                                            181,223      183,452
       Less current portion..............       (18)         (45)
                                           --------     --------
                                           $181,205     $183,407
                                           ========     ========

     The Company has  registered $200.0 million  of unsecured  medium
term debt securities  ("Medium Term Notes")  of which $113.0  million
were outstanding at  March 31, 1995.   These Medium  Term Notes  bear
interest at fixed  rates averaging 5.8%  and mature in  two to  eight
years.

3.   Income taxes

     The provision for  income taxes  consists of  the following  (in
thousands):

                                           Three Months Ended
                                               March 31,
                                             1995      1994
                                           --------  --------

             Federal...................... $48,538   $49,861
             State........................   4,779     7,802
                                           -------   -------
                                           $53,317   $57,663
                                           =======   =======

4.   Contingencies

  Johnson & Johnson arbitration

     In September  1985, the  Company granted  Johnson &  Johnson  an
exclusive license under certain  patented technology and know-how  of
the Company to sell erythropoietin  throughout the United States  for
all human uses except dialysis and diagnostics.

     In  January  1989,  Johnson  &  Johnson  initiated   arbitration
proceedings with respect  to a number  of disputes  which had  arisen
between Amgen and Johnson & Johnson  as to the respective rights  and
obligations of the parties under the various agreements between them.
Amgen filed  a  cross  petition for  arbitration  raising  additional
disputes for  resolution  by  the  arbitrator.    The  scope  of  the
<PAGE>
arbitration  covers   erythropoietin,   hepatitis   B   vaccine   and
interleukin-2.

     In April 1990, the arbitrator ruled that Johnson & Johnson  must
purchase from Amgen all of Johnson  & Johnson's actual United  States
sales requirements of recombinant human erythropoietin.  In  December
1990,  the  U.S.  Food  and  Drug  Administration  approved   Amgen's
application to name Johnson & Johnson  a distributor of Epoetin  alfa
under the trademark PROCRIT(R).  In  January 1991, Johnson &  Johnson
began distributing Epoetin alfa.

     In June 1991, the arbitrator issued an opinion awarding  Johnson
& Johnson $164.0 million on its claims regarding erythropoietin.   In
September 1992,  the  arbitrator found  that  Johnson &  Johnson  had
breached  its   obligations  regarding   hepatitis  B   vaccine   and
interleukin-2, and in January 1993 awarded the Company  approximately
$90.0 million in damages against Johnson & Johnson.  In January 1993,
the Company  paid  Johnson  &  Johnson  the  sum  of  $82.4  million,
representing the  difference between  the damages  awarded Johnson  &
Johnson as a  result of its  erythropoietin claims,  and the  amounts
awarded Amgen against Johnson & Johnson as a result of its  hepatitis
B vaccine and interleukin-2 claims, plus interest.  Johnson & Johnson
returned to the Company the rights to develop and market hepatitis  B
vaccine and interleukin-2 in March 1991.

     The Company and  Johnson &  Johnson are  required to  compensate
each other for Epoetin alfa sales  which either party makes into  the
other party's contractual market.  The Company has established and is
employing an accounting methodology to  assign the proceeds of  sales
of EPOGEN(R)  and  PROCRIT(R)  in Amgen's  and  Johnson  &  Johnson's
respective contractual markets.   The  Company has  made payments  to
Johnson & Johnson based upon the results of the Company's  accounting
methodology.  Johnson & Johnson has disputed the methodology employed
by the  Company  and  is proposing  an  alternative  methodology  for
adoption by  the arbitrator.   If,  as a  result of  the  arbitration
proceeding, a methodology different  from that currently employed  by
the Company is instituted to assign the proceeds of sales between the
parties, it may yield results that are different from the results  of
the accounting methodology currently employed by  the Company.  As  a
result of  the arbitration,  it is  possible that  the Company  would
recognize a different  level of  EPOGEN(R) sales  than are  currently
being recognized.  As a result of the arbitration, the Company may be
required to  pay additional  compensation to  Johnson &  Johnson  for
sales during prior periods, or Johnson  & Johnson may be required  to
pay compensation to the Company for such prior period sales.  Due  to
the  uncertainties  of  any   arbitrated  result,  the  Company   has
established net liabilities that exceed the amounts paid to Johnson &
Johnson.

     A trial  date  has been  set  for  October 2,  1995  before  the
arbitrator regarding  the accounting  methodologies and  compensation
for sales by Johnson  & Johnson into  Amgen's contractual market  and
sales  by  Amgen  into   Johnson  &  Johnson's  contractual   market.
Discovery as to these issues is in progress.
<PAGE>
  Synergen litigation

     Acquisition litigation

     The Company and its wholly owned subsidiary, Amgen Boulder  Inc.
(formerly  Synergen),  have  been  named  as  defendants  in  several
lawsuits  filed  in  connection  with  the  Company's  December  1994
acquisition of Synergen (the "Acquisition").  One suit, brought by
plaintiffs seeking to represent a  class of Synergen warrant  holders
who claim to  have been deprived  of the benefit  of their  warrants,
includes a request for general damages  in the sum of $34.3  million.
The balance of the suits have been brought by plaintiffs who seek  to
represent a class of  stockholders of Synergen  common stock.   These
plaintiffs seek  an unspecified  amount of  compensatory damages,  an
order rescinding the Acquisition  and related equitable relief  based
upon allegations that the defendants breached their fiduciary  duties
by failing to maximize stockholder value and defrauded the plaintiffs
by omitting  to disclose  allegedly material  information  concerning
Synergen's future prospects.

     ANTRIL(TM) litigation

     Several lawsuits  have  been  filed  against  Synergen  alleging
misrepresentations in connection with its research and development of
ANTRIL(TM) for the treatment  of sepsis.  One  suit brought by  three
Synergen stockholders alleges  violations of  state securities  laws,
fraud and  misrepresentation  and  seeks  an  unspecified  amount  of
compensatory damages and punitive damages.  Another suit, proposed as
a class action,  filed by  a limited  partner of  a partnership  with
which Synergen is  affiliated, seeks rescission  of certain  payments
made to one of the defendants  (or unspecified damages not less  than
$50.0 million) and treble damages based on a variety of allegations.

     While it is not possible to predict accurately or determine  the
eventual outcome of the Johnson  & Johnson arbitration, the  Synergen
litigation or  various other    legal proceedings  (including  patent
disputes) involving Amgen, the Company  believes that the outcome  of
these proceedings  will not  have a  material adverse  effect on  its
financial statements.

5.   Stockholders' equity

     During the  three  months  ended March  31,  1995,  the  Company
repurchased 1.2 million shares of its common stock at a total cost of
$75.2 million under its  common stock repurchase  program.  At  March
31, 1995,  $256.0 million  of the  amount approved  by the  Board  of
Directors remained  available  for repurchase  through  December  31,
1995.  Stock repurchased under the program has been retired and  such
repurchases offset  the dilutive effect of the Company's stock option
and stock purchase plans.
<PAGE>
Item 2.   Management's Discussion and Analysis of Financial Condition
          and Results of Operations

Liquidity and Capital Resources

     Cash provided by operating activities  has been and is  expected
to continue to be the Company's primary source of funds.  During  the
three months ended March 31, 1995, operations provided $156.3 million
of cash  compared with  $116.7 million  during the  same period  last
year.    The  Company  had  cash,  cash  equivalents  and  marketable
securities of $767.4 million at March 31, 1995, compared with  $696.7
million at December 31, 1994.

     Capital expenditures totaled $25.0 million for the three  months
ended March 31, 1995, compared with $37.0 million for the same period
a year ago.  Over  the next few years,  the Company expects to  spend
approximately $100.0 million  to $200.0 million  per year on  capital
projects to expand the Company's global operations.

     The Company receives  cash from the  exercise of employee  stock
options.  During the three months ended March 31, 1995, stock options
and their  related  tax  benefits  provided  $29.5  million  of  cash
compared with $9.7 million for the  period last year.  Proceeds  from
the exercise of  stock options and  their related  tax benefits  will
vary from  period to  period based  upon fluctuations  in the  market
value of the Company's stock relative  to the exercise price of  such
options, among other factors.

     The Company  has a  common stock  repurchase program  to  offset
the dilutive effect of its employee benefit  stock option  and  stock
purchase plans.  Since its inception in 1992 through March 31,  1995,
the Company has repurchased $669.0 million of its common stock and is
authorized to purchase  up to  an additional  $256.0 million  through
December 31, 1995.  During the three months ended March 31, 1995, the
Company purchased 1.2  million shares of  common stock at  a cost  of
$75.2 million compared with 1.8 million shares purchased at a cost of
$75.1 million during the same period last year.

     To provide for  financial flexibility  and increased  liquidity,
the Company has established several sources  of debt financing.   The
Company has filed a shelf registration statement with the  Securities
and Exchange  Commission under  which it  could  issue up  to  $200.0
million of Medium Term Notes.   At March 31, 1995, $113.0 million  of
Medium Term  Notes were  outstanding which  mature  in two  to  eight
years.  The Company has a commercial paper program which provides for
short-term borrowings  up  to  an aggregate  face  amount  of  $200.0
million.  At March  31, 1995, $99.3 million  of commercial paper  was
outstanding, all  with maturities  of  less than three  months.   The
Company also has a $150.0 million revolving line of credit, principally
to support the Company's commercial paper program.  No borrowings  on
this line of credit were outstanding at March 31, 1995.

     The Company invests its  cash in accordance  with a policy  that
seeks to maximize returns while  ensuring both liquidity and  minimal
risk of principal  loss.  The  policy limits  investments to  certain
<PAGE>
types of  instruments issued  by institutions  with investment  grade
credit  ratings,   and   places  restrictions   on   maturities   and
concentration by  type  and  issuer.    The  Company's  fixed  income
investments  are  subject  to  the  risk  of  market  interest   rate
fluctuations, and all  of the  Company's investments  are subject  to
risks associated with  the ability of  the issuers  to perform  their
obligations under the instruments.

     The Company  has a  program to  manage certain  portions of  its
exposure to fluctuations in foreign  currency exchange rates.   These
exposures primarily result from European  sales.  The Company  hedges
the related receivables with foreign currency forward contracts,  all
of which mature within six months.  The Company uses foreign currency
option and forward contracts which generally expire within 12  months
to hedge  certain  anticipated future  cash  flows related  to  these
sales.  At March 31, 1995,  outstanding option and forward  contracts
totaled $24.4 million and $73.0 million, respectively.

     The Company believes  that existing funds,  cash generated  from
operations, and existing sources of  debt financing will be  adequate
to satisfy its working  capital and capital expenditure  requirements
and  to  support  its  common   stock  repurchase  program  for   the
foreseeable future.    However,  the  Company  may  raise  additional
capital from time to time to  take advantage of favorable  conditions
in  the  markets  or  in  connection  with  the  Company's  corporate
development activities.

Results of Operations

Product sales

     Product sales  increased  $65.5 million  or  19% for  the  three
months ended March 31, 1995, compared with the same period last year.

  NEUPOGEN(R) (Filgrastim)

     NEUPOGEN(R) sales were $212.4 million for the three months ended
March 31, 1995,  an increase of  $30.7 million or  17% over the  same
period last year.

     Domestic sales of NEUPOGEN(R) were $147.3 million for the  three
months ended March 31, 1995, an increase of $15.3 million or 12% over
the same  period  last year.    This  increase is  primarily  due  to
increased penetration of the market for colony-stimulating factors.

     Quarterly NEUPOGEN(R)  sales  volume  in the  United  States  is
influenced by  a  number  of  factors  including  underlying  demand,
seasonality of  cancer  chemotherapy  administration  and  wholesaler
inventory management practices.  Wholesaler inventory reductions tend
to reduce NEUPOGEN(R) sales in the first quarter.

     International sales of  NEUPOGEN(R), primarily  in Europe,  were
$65.0 million for the three months ended March 31, 1995, an  increase
of $15.4  million or  31% over  the  same period  last year.    Three
factors, each contributing approximately one third of reported  sales
<PAGE>
growth, account for this increase:  increased market penetration, the
favorable effects of  strengthened foreign  currencies, and  Austria,
Sweden, and Finland joining the European Union ("EU").  Prior to  the
entry of Austria, Sweden, and Finland into the EU on January 1, 1995,
F. Hoffmann La Roche, Amgen's licensee, paid the Company royalties on
sales in these countries.  The Company's overall share of the colony-
stimulating factor market in the EU has decreased slightly  following
the introduction of a competing G-CSF product by Rhone Poulenc  Rorer
and Chugai Pharmaceutical Co., Ltd. in 1994.

     The Company believes that 1995 worldwide NEUPOGEN(R) sales  will
continue to  grow at  a double  digit rate  but lower  than the  1994
growth rate.   NEUPOGEN(R)  sales increases  are primarily  dependent
upon further penetration of existing  markets, the timing and  nature
of additional indications for which the product may be approved,  and
the effects  of competitive  products.   In  addition,  international
NEUPOGEN(R) sales will continue to be  subject to changes in  foreign
currency exchange rates and increased competition.

  EPOGEN(R) (Epoetin alfa)

     EPOGEN(R) sales were $198.9 million  for the three months  ended
March 31, 1995,  an increase of  $34.8 million or  21% over the  same
period last year.  This increase  is primarily due to an increase  in
the U.S. dialysis  patient population, the  administration of  higher
doses of  EPOGEN(R) per  patient, and  increased penetration  of  the
dialysis market.  The Company anticipates that increases in the  U.S.
dialysis patient population and increases in dosing will continue  to
drive EPOGEN(R) sales.  The annual  growth rate for 1995 is  expected
to be in  double digits  but lower  than the  1994 growth  rate.   In
addition, the continued  growth in sales  volume may  be affected  by
future changes in reimbursement rates or the basis for  reimbursement
by the federal government.

Cost of sales

     Cost of sales  as a percentage  of product sales  was 16.2%  and
15.4%  for  the  three  months  ended   March  31,  1995  and   1994,
respectively.   The increase  in cost  of sales  as a  percentage  of
product sales is primarily the result of current year period sales of
inventory with higher unit costs  which were manufactured in  smaller
production  runs  at  the   Company's  Puerto  Rico   fill-and-finish
facility.  Cost of sales as a percentage of product sales is expected
to slightly decline in the second half of the current year when lower
unit cost inventories are sold.

Research and development

     During the  three  months ended  March  31, 1995,  research  and
development expenses increased $40.2 million or 54% compared with the
same period  last year.   This  increase is  primarily due  to a  $20
million  signing  payment  due  The  Rockefeller  University  for  an
exclusive license to  certain technologies  and an  expansion of  the
Company's internal  research and  development staff,  partially as  a
result of the  acquisition of  Synergen, Inc.  ("Synergen").   Annual
research and development expenses are expected to increase at a  rate
<PAGE>
exceeding the anticipated  annual product  sales growth  rate due  to
planned increases in  internal efforts on  new product discovery  and
development and increases in  external research collaboration  costs,
including acquisitions of product and technology rights.

Marketing and selling

     Marketing and  selling expenses  increased $5.6  million or  11%
during the three months ended March  31, 1995 compared with the  same
period last year.  This increase primarily reflects marketing efforts
to improve  NEUPOGEN(R) market  penetration and  EPOGEN(R)  marketing
efforts to bring  more patients within  the target hematocrit  range.
The future growth rate of marketing and selling expenses is  expected
to be lower than the anticipated annual product sales growth rate.

General and administrative

     General and administrative  expenses increased  $6.3 million  or
22% during the three  months ended March 31,  1995 compared with  the
same period last  year.   This increase  is primarily  due to  higher
legal and staff-related expenses.  The future growth rate of  general
and  administrative  expenses  is  expected  to  be  less  than   the
anticipated annual product sales growth rate.

Interest and other income

     Interest and other income increased $7.4 million or 134%  during
the three months ended March 31,  1995 compared with the same  period
last year.  This increase is primarily due to capital losses incurred
in the Company's  investment portfolio  during the  first quarter  of
1994 but  not in  the  current year  period.   These  capital  losses
resulted from the sale of certain fixed income investments which  had
declined in market value because of the increase in interest rates.

Income taxes

     The Company's  effective tax  rate for  the three  months  ended
March 31, 1995 was 32.9% compared with 38.2% for the same period last
year.  The decrease in the tax rate  is due to tax benefits from  the
sale of  products manufactured  in  the Puerto  Rico  fill-and-finish
facility which  began  in the  first  quarter  of 1995.    These  tax
benefits are expected to result in  an annualized effective tax  rate
of 32%-34%.

Legal Matters

     The Company is  engaged in arbitration  proceedings with one  of
its licensees  and various  legal proceedings  relating to  Synergen.
For a  discussion  of these  matters  see  Note 4  to  the  Condensed
Consolidated Financial Statements.
<PAGE>
                     PART II - OTHER INFORMATION

Item 1.   Legal Proceedings

     The Company is  engaged in arbitration  proceedings with one  of
its licensees.  For a complete  discussion of this matter see Note  4
to  the  Consolidated  Financial  Statements  -  "Johnson  &  Johnson
arbitration".  Other legal proceedings are discussed below.  While it
is not possible to  predict accurately or  to determine the  eventual
outcome of these matters,  the Company believes  that the outcome  of
these legal proceedings will  not have a  material adverse effect  on
the financial statements of the Company.

Synergen litigation

  Acquisition litigation

     The Company and its wholly-owned subsidiary, Amgen Boulder  Inc.
(formerly Synergen, Inc.)  have been named  as defendants in  several
lawsuits  filed  in  connection  with  the  Company's  December  1994
acquisition of Synergen (the "Acquisition").    One suit, Stanley, et
al. v.  Soll,  et   al.,  was  filed  on November  18,  1994  by  two
stockholders in the Court of Chancery of the State of Delaware in New
Castle County against Synergen and certain of its former officers and
directors.  Plaintiffs, who seek to represent a class of stockholders
of Synergen common stock, allege  that the defendants breached  their
fiduciary  duties   by  failing   to  maximize   stockholder   value.
Plaintiffs seek  an unspecified  amount of  compensatory damages,  an
order rescinding  the  Acquisition,  and  related  equitable  relief.
Other stockholders seeking the same relief filed suits on November 23
and 29, 1994 and February 28,  1995 in United States District  Court,
County of  Boulder, State  of Colorado.   In  Livergood v.  Synergen,
Inc., et al.,  Weld, et al.  v. Amgen Inc.,  et al.,  and Reineke  v.
Synergen,  Inc.,  et  al.,  the  plaintiffs  allege  that  defendants
Synergen,  Amgen  and  certain  of  Synergen's  former  officers  and
directors  breached  their   fiduciary  duties   and  defrauded   the
plaintiffs by  omitting to  disclose allegedly  material  information
concerning Synergen's future  prospects.  Plaintiffs  in these  cases
seek to represent a class of  stockholders of Synergen common  stock.
On March 8, 1995, the Livergood  and Weld actions were  consolidated,
and the  plaintiff  in the  Reineke  case also  seeks  consolidation.
Another suit,  Glick v.  Synergen, Inc.,  et al.,  was filed  in  the
Superior Court of the State of California, County of Los Angeles,  as
a class  action  on  January  24, 1995  by  plaintiffs  who  seek  to
represent all  warrant holders  of Synergen  who claim  to have  been
deprived of the benefit of their  warrants.  Plaintiffs seek  general
damages in  the sum  of $34.3  million  against Synergen,  Amgen  and
former officers and  directors of  Synergen based  on allegations  of
conspiracy,  breach   of   duty,  self-dealing,   interference   with
prospective business advantage and unjust  enrichment.  On April  18,
1995, this suit was dismissed with leave to amend.

  ANTRIL(TM) litigation

     Several lawsuits  have  been  filed  against  Synergen  alleging
misrepresentations in connection with its research and development of
<PAGE>
ANTRIL(TM) for  the  treatment of  sepsis.    In Temple,  et  al.  v.
Synergen, Inc., et al., three stockholders filed suit on November 15,
1994 in the District Court for  the City and County of Denver,  State
of Colorado, against  Synergen and  a former  director and  executive
officer, alleging  violations  of  state securities  law,  fraud  and
misrepresentation.    Plaintiffs  seek   an  unspecified  amount   of
compensatory damages  and  punitive damages.    In Johnson  v.  Amgen
Boulder, Inc.,  et al.,  suits filed  on  February 14,  1995  in the
Superior Court for the  State of Washington, King  County and in  the
United States District Court for the Western District of  Washington,
plaintiff seeks rescission  of certain payments  made to  one of  the
defendants (or unspecified damages not  less than $50.0 million)  and
treble damages.  Plaintiff, a  limited partner of defendant  Synergen
Clinical Partners, L.P., seeks to represent a class of other  limited
partners.   The complaints  allege violations  of federal  and  state
securities laws,  violations of  other  federal and  state  statutes,
fraud, negligence,  breach  of  contract, conspiracy  and  breach  of
fiduciary duty.  The  defendants include Synergen, Synergen  Clinical
Partners, L.P., Synergen Development Corporation and former  officers
and directors  of  Synergen.   The  Superior Court  action  has  been
removed to federal court and consolidated with the suit filed in  the
United States District Court for the Western District of Washington.

Elanex Pharmaceuticals litigation

     In October  1993,  the  Company filed  a  complaint  for  patent
infringement  against   defendants   Elanex   Pharmaceuticals,   Inc.
("Elanex"), Laboratorios Elanex De Costa Rica, S. A., Bio Sidus S.A.,
Merckle GmbH, Biosintetica S. A. and  other unknown defendants.   The
complaint, filed in the United States District Court for the  Western
District of  Washington  at  Seattle,  seeks  injunctive  relief  and
damages for Elanex's  infringement of  the Company's  patent for  DNA
sequences  and   host   cells   useful   in   producing   recombinant
erythropoietin.    The  complaint  also  alleges  that  the   foreign
defendants entered  into  agreements  with  Elanex  relating  to  the
production or  sale of  recombinant erythropoietin  and thereby  have
induced Elanex's infringement.

     In December 1993, Elanex responded to the complaint denying  the
material allegations  thereof, and  filed  a counterclaim  seeking  a
declaratory judgment that  the Company's patent  is invalid and  that
Elanex's recombinant erythropoietin technology does not infringe  any
valid claims of the Company's patent.  The counterclaim also seeks an
award of reasonable attorneys'  fees and other  costs of defense  but
does not seek damages against the Company.  The case is currently  in
discovery.

Erythropoietin patent litigation

     Amgen has been  engaged in  litigation (the  "Amgen suit")  with
Genetics Institute, Inc.  ("Genetics Institute")  and its  commercial
partner, Chugai Pharmaceutical Co., Ltd., regarding the  infringement
of Amgen's  patent on  the DNA  sequence used  in the  production  of
erythropoietin (the "Amgen Patent")  and the infringement by  Amgen's
erythropoietin product of a patent held by Genetics Institute.
<PAGE>
     Genetics Institute and  the Company  announced on  May 11,  1993
that they agreed  to settle all  outstanding patent disputes  between
them regarding erythropoietin in the United  States.  As part of  the
settlement, Genetics Institute paid the Company $13.9 million  during
the quarter ended September 30, 1993.   An additional $2 million  may
be paid to the Company contingent upon the outcome of certain  future
events.   As a  result of  the settlement  of the  litigation,  Amgen
expects to receive patents on  the process for producing  recombinant
erythropoietin and on the recombinant erythropoietin product.

     In August  1991,  Johnson &  Johnson,  together with  eleven  of
Johnson & Johnson's Cilag European subsidiaries, filed a suit in  the
United States District  Court for  the District  of Massachusetts  in
Boston, the site of  the Amgen suit  against Genetics Institute  (the
"Boston  Court"),  seeking  damages   from  Genetics  Institute   for
infringement of the Amgen Patent (the  "Johnson & Johnson suit")  and
moved to consolidate  the Johnson &  Johnson suit  with the  original
suit filed by Amgen.  The  two suits were consolidated by the  Boston
Court.  Amgen was allowed to intervene in the Johnson & Johnson  suit
for the limited purpose of seeking a summary judgment dismissing  the
Johnson  &  Johnson  suit.    In  December  1992,  the  Boston  Court
determined that Johnson  & Johnson had  no standing  to sue  Genetics
Institute and entered  judgment and dismissed  the Johnson &  Johnson
suit.  Also,  in December 1992,  the Boston Court  denied motions  by
Johnson & Johnson  to intervene  in the  Amgen suit  for the  limited
purpose of  seeking  a  summary  judgment  limiting  Amgen's  damages
against Genetics Institute.   Johnson &  Johnson appealed the  Boston
Court's December 1992 rulings, and on  April 5, 1995, the U.S.  Court
of Appeals for the Federal Circuit upheld the December 1992 rulings.

Genetics Institute litigation

     On June 21, 1994,  Genetics Institute filed  suit in the  United
States District Court  for the  District of  Delaware in  Wilmington,
against Johnson & Johnson, a licensee and distributor of the Company,
seeking damages for  the alleged  infringement of  a recently  issued
U.S. Patent 5,322,837  relating to Johnson  & Johnson's  manufacture,
use, and sale of erythropoietin.

     On September  12, 1994,  the Company  filed suit  in the  United
States District Court  for the District  of Massachusetts in  Boston,
against Genetics Institute,  seeking declaratory  judgment of  patent
non-infringement, invalidity  and unenforceability  against  Genetics
Institute in  respect to  U.S. Patent  5,322,837 issued  to  Genetics
Institute, which  relates to  homogeneous erythropoietin.    Genetics
Institute answered the complaint and filed a counterclaim against the
Company alleging infringement of  the same patent.   On February  14,
1995,  the  United  States  District   Court  for  the  District   of
Massachusetts granted Amgen's motion for a summary judgment enforcing
a prior  judgment against  Genetics  Institute and  barring  Genetics
Institute from asserting  its U.S. Patent  5,322,837 against  Amgen's
recombinant erythropoietin.   On March 13,  1995, Genetics  Institute
filed notice of appeal.
<PAGE>
Biogen litigation

     On June  15, 1994,  Biogen, Inc.  ("Biogen") filed  suit in  the
Tokyo District Court in  Japan, against Amgen  K.K., a subsidiary  of
the Company, seeking injunctive  relief for the alleged  infringement
of two Japanese patents relating to alpha-interferon.

     On March  10,  1995, Biogen  filed  suit in  the  United  States
District  Court  for  the   District  of  Massachusetts  seeking   an
unspecified  amount  of  compensatory  damages,  treble  damages  and
injunctive relief of  its U.S. Patent  4,874,702 relating to  vectors
for expressing cloned genes.  Biogen alleges that Amgen has infringed
its patent by manufacturing and selling NEUPOGEN(R).


Item 6.   Exhibits and Reports on Form 8-K

     (a)  Reference is made to the Index to Exhibits included herein.

     (b)  Reports on Form 8-K

     The Company filed a report on  Form 8-K dated February 21,  1995
reporting an amendment to its Rights  Agreement, dated as of  January
24, 1989,  between Amgen  Inc. and  American Stock  Transfer &  Trust
Company, as Rights Agent, as amended.
<PAGE>
                             SIGNATURES


     Pursuant to the requirements of  the Securities Exchange Act  of
1934, the registrant has duly caused this report to be signed on  its
behalf by the undersigned thereunto duly authorized.


                                     Amgen Inc.
                                     (Registrant)



Date:     5/12/95                    By:/s/        Robert S. Attiyeh
- ------------------                   ------------------------------------
                                        Robert S. Attiyeh
                                        Senior Vice President, Finance
                                        and Corporate Development, and
                                        Chief Financial Officer




Date:     5/12/95                    By:/s/          Larry A. May
- ------------------                   ------------------------------------
                                        Larry A. May
                                        Vice President, Corporate
                                        Controller and Chief
                                        Accounting Officer
<PAGE>
                             AMGEN INC.


                          INDEX TO EXHIBITS


Exhibit No.                     Description

  3.1       Restated Certificate of Incorporation. (7)
  3.2       Certificate of  Amendment  to  Restated  Certificate  of
            Incorporation, effective as of July 24, 1991. (14)
  3.3       Bylaws, as amended to date. (20)
  4.1       Indenture dated January 1, 1992 between  the Company and
            Citibank N.A., as trustee. (15)
  4.2       Forms of Commercial Paper Master Note Certificates. (19)
 10.1*      Company's 1991 Equity Incentive Plan, as amended. (16)
 10.2*      Company's 1984 Stock Option Plan, as  amended, and forms
            of Incentive Stock  Option Grant and  Nonqualified Stock
            Option Grant used in connection therewith. (16)
 10.3       Shareholder's Agreement of Kirin-Amgen,  Inc., dated May
            11, 1984, between the Company and Kirin Brewery Company,
            Limited (with  certain confidential  information deleted
            therefrom). (1)
 10.4       Amendment Nos. 1, 2,  and 3, dated March  19, 1985, July
            29, 1985  and December  19, 1985,  respectively, to  the
            Shareholder's Agreement of Kirin-Amgen,  Inc., dated May
            11, 1984 (with certain  confidential information deleted
            therefrom). (3)
 10.5       Product License Agreement, dated September 30, 1985, and
            Technology License Agreement, dated,  September 30, 1985
            between the Company and Ortho Pharmaceutical Corporation
            (with   certain    confidential   information    deleted
            therefrom). (2)
 10.6       Product License Agreement, dated September 30, 1985, and
            Technology License Agreement,  dated September  30, 1985
            between  Kirin-Amgen,  Inc.  and   Ortho  Pharmaceutical
            Corporation  (with   certain  confidential   information
            deleted therefrom). (3)
 10.7*      Company's Employee Stock Purchase Plan, amended April 1,
            1992. (17)
 10.8       Agreement, dated February 12, 1986,  between the Company
            and Sloan-Kettering Institute for  Cancer Research (with
            certain confidential information deleted therefrom). (4)
 10.9       Amendment No. 2, dated November 13,  1990, to Agreement,
            dated February 12, 1986, between the  Company and Sloan-
            Kettering Institute  for Cancer  Research (with  certain
            confidential information deleted therefrom). (13)
 10.10      Research, Development Technology Disclosure  and License
            Agreement PPO, dated  January 20,  1986, by  and between
            the Company and Kirin Brewery Co., Ltd. (4)
 10.11      Research Collaboration Agreement, dated August 31, 1990,
            between Amgen Inc.  and Regeneron  Pharmaceuticals, Inc.
            (with   certain    confidential   information    deleted
            therefrom). (13)
 10.12      Amendment  Nos.  4  and   5,  dated  October   16,  1986
            (effective July 1, 1986) and December 6, 1986 (effective
<PAGE>
            July  1,  1986),   respectively,  to   the  Shareholders
            Agreement of Kirin-Amgen, Inc. dated May  11, 1984 (with
            certain confidential information deleted therefrom). (5)
 10.13      Assignment and  License  Agreement,  dated  October  16,
            1986, between  the Company  and Kirin-Amgen,  Inc. (with
            certain confidential information deleted therefrom). (5)
 10.14      G-CSF European  License  Agreement,  dated December  30,
            1986, between  Kirin-Amgen, Inc.  and the  Company (with
            certain confidential information deleted therefrom). (5)
 10.15      Research  and  Development  Technology   Disclosure  and
            License Agreement: GM-CSF, dated March 31, 1987, between
            Kirin Brewery  Company, Limited  and  the Company  (with
            certain confidential information deleted therefrom). (5)
 10.16*     Company's 1987 Directors' Stock Option Plan, as amended.
            (13)
 10.17      Cross License  Agreement, dated  June  1, 1987,  between
            Amgen Inc. and Amgen Clinical Partners, L.P. (6)
 10.18      Development Agreement, dated June 1, 1987, between Amgen
            Inc. and Amgen Clinical Partners, L.P. (6)
 10.19      Joint Venture  Agreement, dated  June  1, 1987,  between
            Amgen Inc. and Amgen Clinical Partners, L.P. (6)
 10.20      Partnership Purchase  Option  Agreement,  dated June  1,
            1987, between  Amgen Inc.  and Amgen  Clinical Partners,
            L.P. (6)
 10.21*     Company's 1988 Stock Option Plan, as amended. (16)
 10.22*     Company's  Retirement  and  Savings  Plan,  amended  and
            restated as of January 1, 1993. (17)
 10.23      Amendment,   dated   June   30,   1988,   to   Research,
            Development,   Technology    Disclosure   and    License
            Agreement: GM-CSF  dated March  31, 1987,  between Kirin
            Brewery Company, Limited and the Company. (7)
 10.24      Amending Agreement, dated June 30,  1988, to Development
            Agreement,  Partner  Purchase  Option  Agreement,  Cross
            License Agreement  and  Joint  Venture Agreement,  dated
            June 1,  1987, between  the Company  and Amgen  Clinical
            Partners, L.P. (7)
 10.25      Agreement on G-CSF in the EU,  dated September 26, 1988,
            between Amgen  Inc.  and  F.  Hoffmann-La  Roche  &  Co.
            Limited Company  (with certain  confidential information
            deleted therefrom). (9)
 10.26      Supplementary Agreement  to Agreement  dated January  4,
            1989 to Agreement  on G-CSF in  the EU,  dated September
            26, 1988, between the Company and F. Hoffmann-La Roche &
            Co.  Limited   Company,   (with   certain   confidential
            information deleted therefrom). (9)
 10.27      Agreement on G-CSF in Certain  European Countries, dated
            January 1, 1989, between  Amgen Inc. and  F. Hoffmann-La
            Roche & Co.  Limited Company (with  certain confidential
            information deleted therefrom). (9)
 10.28      Rights Agreement, dated January 24,  1989, between Amgen
            Inc. and  American  Stock  Transfer and  Trust  Company,
            Rights Agent. (8)
 10.29      First Amendment to  Rights Agreement, dated  January 22,
            1991, between Amgen Inc. and American Stock Transfer and
            Trust Company, Rights Agent. (11)
<PAGE>
 10.30      Second Amendment  to Rights  Agreement,  dated April  2,
            1991, between Amgen Inc. and American Stock Transfer and
            Trust Company, Rights Agent. (12)
 10.31      Credit Agreement, dated as  of November 15,  1991, among
            Amgen Inc.,  The Borrowing  Subsidiaries therein  named,
            the Banks  therein  named,  Swiss Bank  Corporation,  as
            issuing Bank  and Swiss  Bank  Corporation and  Citicorp
            USA, Inc., as Co-Agents. (17)
 10.32      Deed of  Trust  and Security  Agreement,  dated June  1,
            1989,  between  the  Company  and  UNUM  Life  Insurance
            Company of America. (10)
 10.33      Note, dated June 1,  1989, between the Company  and UNUM
            Life Insurance Company of America. (10)
 10.34      Agency Agreement, dated November 21, 1991, between Amgen
            Manufacturing,  Inc.  and  Citicorp  Financial  Services
            Corporation. (17)
 10.35      Agency Agreement,  dated  May  21, 1992,  between  Amgen
            Manufacturing,  Inc.  and  Citicorp  Financial  Services
            Corporation. (17)
 10.36      Guaranty, dated July 29,  1992, by the Company  in favor
            of Merck Sharp & Dohme Quimica de Puerto Rico, Inc. (17)
 10.37      936 Promissory  Note No.  01, dated  December 11,  1991,
            issued by Amgen Manufacturing, Inc. (17)
 10.38      936 Promissory  Note No.  02, dated  December 11,  1991,
            issued by Amgen Manufacturing, Inc. (17)
 10.39      936 Promissory Note No. 001, dated July 29, 1992, issued
            by Amgen Manufacturing, Inc. (17)
 10.40      936 Promissory Note No. 002, dated July 29, 1992, issued
            by Amgen Manufacturing, Inc. (17)
 10.41      Guaranty, dated  November 21,  1991, by  the Company  in
            favor of Citicorp Financial Services Corporation. (17)
 10.42      First Amendment,  dated  as of  June  16,  1992, to  the
            Credit Agreement, dated as  of November 15,  1991, among
            Amgen Inc.,  The Borrowing  Subsidiaries therein  named,
            the Banks  therein  named,  Swiss Bank  Corporation,  as
            issuing Bank  and Swiss  Bank  Corporation and  Citicorp
            USA, Inc., as Co-Agents. (17)
 10.43      Second Amendment, dated as  of November 6, 1992,  to the
            Credit Agreement, dated as  of November 15,  1991, among
            Amgen Inc.,  The Borrowing  Subsidiaries therein  named,
            the Banks  therein  named,  Swiss Bank  Corporation,  as
            issuing Bank  and Swiss  Bank  Corporation and  Citicorp
            USA, Inc., as Co-Agents. (17)
 10.44      Lease and Agreement relating  to Lease, dated  March 27,
            1986 and  April  1,  1986,  respectively, for  2003  Oak
            Terrace Lane between 2001 Hillcrest  Partnership and the
            Company. (20)
 10.45      Partnership Purchase  Agreement, dated  March 12,  1993,
            between the  Company,  Amgen  Clinical  Partners,  L.P.,
            Amgen  Development  Corporation,  the  Class  A  limited
            partners and the Class B limited partner. (18)
 10.46*     Amgen Supplemental Retirement  Plan dated June  1, 1993.
            (21)
 10.47      Promissory Note of  Mr. Kevin W.  Sharer, dated  June 4,
            1993. (21)
<PAGE>
 10.48      Amendment No.  3  dated  June  25,  1993 to  the  Credit
            Agreement, dated November  15, 1991, among  the Company,
            The Borrowing  Subsidiaries  therein  named,  the  Banks
            therein named,  the Swiss  Bank Corporation,  as issuing
            Bank and Swiss Bank Corporation and  Citicorp USA, Inc.,
            as Co-Agents. (21)
 10.49      Promissory Note of Mr. Larry A.  May, dated February 24,
            1993. (22)
 10.50*     First Amendment dated October 26, 1993  to the Company's
            Retirement and Savings Plan. (22)
 10.51*     Amgen Performance Based Management Incentive Plan. (22)
 10.52      Fourth Amendment,  dated as  of June  24,  1994, to  the
            Credit Agreement,  dated November  15,  1991, among  the
            Company, The Borrowing  Subsidiaries therein  named, the
            Banks therein  named,  the  Swiss Bank  Corporation,  as
            issuing Bank  and Swiss  Bank  Corporation and  Citicorp
            USA, Inc., as Co-Agents. (23)
 10.53      Agreement and Plan of  Merger, dated as of  November 17,
            1994, among  Amgen Inc.,  Amgen Acquisition  Subsidiary,
            Inc. and Synergen, Inc. (24)
 10.54      Third  Amendment  to  Rights  Agreement,   dated  as  of
            February 21, 1995, between Amgen Inc. and American Stock
            Transfer Trust and Trust Company (25)
 11         Computation of per share earnings.
 27         Financial Data Schedule.
- ----------------
* Management contract or compensatory plan or arrangement.

(1)  Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended  March 31,  1984 on  June 26,  1984 and  incorporated
     herein by reference.
(2)  Filed as an  exhibit to Quarterly  Report on Form  10-Q for  the
     quarter ended  September  30,  1985 on  November  14,  1985  and
     incorporated herein by reference.
(3)  Filed as an  exhibit to Quarterly  Report on Form  10-Q for  the
     quarter  ended  December  31,  1985  on  February  3,  1986  and
     incorporated herein by reference.
(4)  Filed as an exhibit to Amendment No. 1 to Form S-1  Registration
     Statement (Registration  No.  33-3069)  on March  11,  1986  and
     incorporated herein by reference.
(5)  Filed as an exhibit to the Form 10-K Annual Report for the  year
     ended March 31, 1987 on May 18, 1987 and incorporated herein by
     reference.
(6)  Filed as an exhibit to the Quarterly Report on Form 10-Q for the
     quarter ended June 30, 1987 on August 12, 1987 and  incorporated
     herein by reference.
(7)  Filed as an exhibit to Form  8 amending the Quarterly Report  on
     Form 10-Q for the quarter ended June 30, 1988 on August 25, 1988
     and incorporated herein by reference.
(8)  Filed as an exhibit to the Form 8-K Current Report dated January
     24, 1989 and incorporated herein by reference.
(9)  Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended  March 31,  1989 on  June 28,  1989 and  incorporated
     herein by reference.
<PAGE>
(10) Filed as an exhibit to the Quarterly Report on Form 10-Q for the
     quarter ended June 30, 1989 on August 14, 1989 and  incorporated
     herein by reference.
(11) Filed as an exhibit to the Form 8-K Current Report dated January
     22, 1991 and incorporated herein by reference.
(12) Filed as an exhibit to the  Form 8-K Current Report dated  April
     12, 1991 and incorporated herein by reference.
(13) Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended  March 31,  1991 on  July  1, 1991  and  incorporated
     herein by reference.
(14) Filed as an exhibit  to the Form 8-K  Current Report dated  July
     24, 1991 and incorporated herein by reference.
(15) Filed as an  exhibit to  Form S-3  Registration Statement  dated
     December 19, 1991 and incorporated herein by reference.
(16) Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended December 31, 1991 on March 30, 1992 and  incorporated
     herein by reference.
(17) Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended December 31, 1992 on March 30, 1993 and  incorporated
     herein by reference.
(18) Filed as an  exhibit to the  Form 8-A dated  March 31, 1993  and
     incorporated herein by reference.
(19) Filed as an exhibit to the Form 10-Q for the quarter ended March
     31, 1993 on May 17, 1993 and incorporated herein by reference.
(20) Filed as an exhibit to the Form 10-Q for the quarter ended  June
     30,  1993  on  August  16,  1993  and  incorporated  herein   by
     reference.
(21) Filed as  an exhibit  to the  Form 10-Q  for the  quarter  ended
     September 30, 1993 on November 12, 1993 and incorporated  herein
     by reference.
(22) Filed as an exhibit  to the Annual Report  on Form 10-K for  the
     year ended December 31, 1993 on March 25, 1994 and  incorporated
     herein by reference.
(23) Filed as an exhibit to the Form 10-Q for the ended September 30,
     1994 on November 9, 1994 and incorporated herein by reference.
(24) Filed as  an  exhibit  to the  Form  8-K  Current  Report  dated
     November 18, 1994 on December 2, 1994 and incorporated herein by
     reference.
(25) Filed as  an  exhibit  to the  Form  8-K  Current  Report  dated
     February 21, 1995 on  March 7, 1995  and incorporated herein  by
     reference.
<PAGE>

                                                           EXHIBIT 11



                             AMGEN INC.

                  COMPUTATION OF PER SHARE EARNINGS
                         PRIMARY COMPUTATION

                (In thousands, except per share data)
                             (Unaudited)


                                                Three Months Ended
                                                    March 31,
                                                 1995       1994  
                                              --------   --------

Net income................................... $108,624   $ 93,460
                                              ========   ========

Applicable common and common stock
  equivalent shares:

   Weighted average shares of common stock
    outstanding during the period............  132,606    133,961

   Incremental number of shares outstanding
    during the period resulting from the
    assumed exercises of stock options and
    warrants.................................    7,146      7,410
                                              --------   --------
Weighted average shares of common stock and
  common stock equivalents outstanding during
  the period.................................  139,752    141,371
                                              ========    =======

Earnings per common share primary............ $    .78   $    .66
                                              ========   ========
<PAGE>
                                                           EXHIBIT 11



                             AMGEN INC.

                  COMPUTATION OF PER SHARE EARNINGS
                      FULLY DILUTED COMPUTATION

                (In thousands, except per share data)
                             (Unaudited)


                                                Three Months Ended
                                                    March 31,
                                                 1995       1994  
                                              --------   --------

Net income................................... $108,624   $ 93,460
                                              ========   ========

Applicable common and common stock
  equivalent shares:

   Weighted average shares of common stock
    outstanding during the period............  132,606    133,961

   Incremental number of shares outstanding
    during the period resulting from the
    assumed exercises of stock options and
    warrants.................................    7,525      7,410
                                              --------   --------

Weighted average shares of common stock and
  common stock equivalents outstanding during
  the period.................................  140,131    141,371
                                              ========   ========

Earnings per common share fully diluted...... $    .78   $    .66
                                              ========   ========
<PAGE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<ARTICLE> 5
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   QTR-1
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-END>                               MAR-31-1995
<CASH>                                         199,024
<SECURITIES>                                   568,359
<RECEIVABLES>                                  201,249
<ALLOWANCES>                                    12,121
<INVENTORY>                                     92,497
<CURRENT-ASSETS>                                49,746
<PP&E>                                         670,596
<DEPRECIATION>                                  19,683
<TOTAL-ASSETS>                               2,052,411
<CURRENT-LIABILITIES>                          533,943
<BONDS>                                              0
<COMMON>                                            13
                                0
                                          0
<OTHER-SE>                                   1,337,250
<TOTAL-LIABILITY-AND-EQUITY>                 2,052,411
<SALES>                                        411,237
<TOTAL-REVENUES>                               439,366
<CGS>                                           66,573
<TOTAL-COSTS>                                  286,540
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                               3,784
<INCOME-PRETAX>                                161,941
<INCOME-TAX>                                    53,317
<INCOME-CONTINUING>                                  0
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   108,624
<EPS-PRIMARY>                                     0.78
<EPS-DILUTED>                                     0.78
        

</TABLE>


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