GENENTECH INC
SC 13G, 1998-04-02
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934

                               (Amendment No. __)*


                              CuraGen Corporation
- --------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   23126R 10 7
- --------------------------------------------------------------------------------
                                 (CUSIP Number)



                                    03/23/98
- --------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

           [ ]  Rule 13d-1(b)
           [X]  Rule 13d-1(c)
           [ ]  Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).




Potential persons who are to respond to the collection of information contained
in this form are not required to respond unless the form displays a currently
valid OMB control number.



<PAGE>   2
CUSIP No. 23126R 10 7


- ------------------------------------------------------------------------------
      1.     Names of Reporting Persons
             I.R.S. Identification Nos. of above persons (entities only)

             Genentech, Inc.
             94-2347624
- ------------------------------------------------------------------------------
      2.     Check the Appropriate Box if a Member of a Group (see instructions)

             Not applicable.

             (a)     [ ]
             (b)     [ ]
- ------------------------------------------------------------------------------
      3.     SEC Use Only

- ------------------------------------------------------------------------------
      4.     Citizenship or Place of Organization

             Delaware
- ------------------------------------------------------------------------------
Number of
Shares                         5.      Sole Voting Power:  741,949
Beneficially                   6.      Shared Voting Power:  0
Owned by                       7.      Sole Dispositive Power:  741,949
Each Reporting                 8.      Shared Dispositive Power:  0
Person With:
- ------------------------------------------------------------------------------
      9.     Aggregate Amount Beneficially Owned by Each Reporting Person:

             741,949
- ------------------------------------------------------------------------------
      10.    Check if the Aggregate Amount in Row (11) Excludes Certain Shares
             (see instructions)

             Not applicable.

             [ ]
- ------------------------------------------------------------------------------
      11. Percent of Class Represented by Amount in Row (11):

             5.8%
- ------------------------------------------------------------------------------
      12. Type of Reporting Person (see instructions)

             CO
- ------------------------------------------------------------------------------




                               Page 2 of 5 Pages

<PAGE>   3

CUSIP No. 23126R 10 7



ITEM 1:

      (a)    Name of Issuer:  CuraGen Corporation

      (b)    Address of Issuer's Principal Executive Offices:

             555 Long Wharf Drive, 11th Floor
             New Haven, Connecticut  06511

ITEM 2:

      (a)    Name of Person Filing:  Genentech, Inc.

      (b)    Address of Principal Business Office or, if none, Residence:

             1 DNA Way
             South San Francisco, California  94080

      (c)    Citizenship:  Delaware

      (d)    Title of Class of Securities:  Common Stock

      (e)    CUSIP Number:  23126R 10 7

ITEM 3: IF THIS STATEMENT IS FILED PURSUANT TO SECTIONS 240.13d-1(b) OR
240.13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A:

      (a)    [ ] Broker or dealer registered under section 15 of the
                 Act (15 U.S.C. 78o);

      (b)    [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

      (c)    [ ] Insurance company as defined in section 3(a)(19) of the Act 
                 (15 U.S.C. 78c);

      (d)    [ ] Investment company registered under section 8 of the Investment
                 Company Act of 1940 (15 U.S.C. 80a-8);

      (e)    [ ] An investment adviser in accordance with Section 240.13d-1(b)
                 (l)(ii)(E);

      (f)    [ ] An employee benefit plan or endowment fund in accordance with
                 Section 240.13d-1 (b)(1)(ii)(F);

      (g)    [ ] A parent holding company or control person in accordance with
                 Section 240.13d-1 (b)(1)(ii)(G);




                                Page 3 of 5 Pages

<PAGE>   4

CUSIP No. 23126R 10 7


      (h)    [ ] A savings association as defined in Section 3(b) of the
                 Federal Deposit Insurance Act (12 U.S.C. 1813);

      (i)    [ ] A church plan that is excluded from the definition of an 
                 investment company under section 3(c)(14) of the Investment 
                 Company Act of 1940 (15 U.S.C. 80a-3);

      (j)    [ ] Group, in accordance with Section 240.13d-1(b)(1)(ii)(J).

ITEM 4:      OWNERSHIP.

      (a)    Amount beneficially owned:  741,949

      (b)    Percent of class:  5.8%

      (c)    Number of shares as to which the person has:

             (i)   Sole power to vote or to direct the vote:  741,949

             (ii)  Shared power to vote or to direct the vote:  0

             (iii) Sole power to dispose or to direct the disposition of:
                                                              741,949

             (iv)  Shared power to dispose or to direct the disposition of:  0

ITEM 5:      OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

      If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following [ ].

ITEM 6:      OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

             Not applicable.

ITEM 7:      IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
             THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.

             Not applicable.

ITEM 8:      IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

             Not applicable.

ITEM 9:      NOTICE OF DISSOLUTION OF GROUP.

             Not applicable.


                                Page 4 of 5 Pages

<PAGE>   5

CUSIP No. 23126R 10 7


ITEM 10:     CERTIFICATION.

      (a)    Not applicable.

      (b)    By signing below I certify that, to the best of my knowledge and
             belief, the securities referred to above were not acquired and are
             not held for the purpose of or with the effect of changing or
             influencing the control of the issuer of the securities and were
             not acquired and are not held in connection with or as a
             participant in any transaction having that purpose or effect.



                                    SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.



                                                    April 2, 1998
                                              ------------------------------
                                                        Date



                                              /s/ STEPHEN G. JUELSGAARD
                                              ------------------------------
                                                       Signature

                                              Stephen G. Juelsgaard
                                              Vice President, Secretary and
                                              General Counsel
                                              ------------------------------
                                                         Name/Title







                               Page 5 of 5 Pages


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