MERRILL LYNCH SERIES FUND INC
24F-2NT, 1994-02-28
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February 28, 1994



Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, N.W.
Washington, DC  20549

Re:  Rule 24f-2 Notice for
     MERRILL LYNCH SERIES FUND, INC.
     File No. 2-69062

Dear Sirs:

In accordance with the provisions of Rule 24f-2
under the Investment Company Act of 1940, Merrill
Lynch Series Fund, Inc. (the "Fund") hereby files
its Rule 24f-2 notice (the "Notice").

This Notice is being filed for the fiscal year of
the Fund ended December 31, 1993 (the "Fiscal
Year") and covers each of the following ten
portfolios of Common Stock of the Fund:  Money
Reserve Portfolio Common Stock, Intermediate
Government Bond Portfolio Common Stock, Long Term
Corporate Bond Portfolio Common Stock, Capital
Stock Portfolio Common Stock, Growth Stock
Portfolio Common Stock, Multiple Strategy
Portfolio Common Stock, High Yield Portfolio
Common Stock, Natural Resources Portfolio Common
Stock, Global Strategy Portfolio Common Stock and
Balanced Portfolio Common Stock (collectively
referred to herein as the "Portfolios").

Set forth below is the information required by
Rule 24f-2 for each portfolio of Common Stock of the
Fund.  Included in such information are the
calculations on which the filing fee of $46,144.16
are based.

I.   Money Reserve Portfolio Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the Securities 
      Act of 1933 (the "Securities Act") other than
      pursuant to Rule 24f-2 remained unsold at the
      beginning of the Fiscal Year.

2.   286,128,453 shares of common stock of the
      Portfolio were registered under the Securities Act
      during the Fiscal Year other than pursuant to
      Rule 24f-2.

3.   159,076,741 shares of common stock of the
      Portfolio were sold during the Fiscal Year.*

4.   No shares of common stock of the Portfolio
      were sold during the Fiscal Year in reliance
      upon registration pursuant to Rule 24f-2.
<PAGE>


II.  Intermediate Government Bond Portfolio
            Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the
      Securities Act other than pursuant to
      Rule 24f-2 remain unsold at the beginning 
      of the Fiscal Year.

2.   3,180,538 shares of common stock of the
      Portfolio were registered under the Securities 
      Act other than pursuant to Rule 24f-2.

3.   2,470,581 shares of common stock of the
     Portfolio were sold during the Fiscal Year.**
   
4.   No shares of common stock of the Portfolio
      were sold during the Fiscal Year in reliance 
      upon registration pursuant to Rule 24f-2.
   

III. Long Term Corporate Bond Portfolio 
        Common Stock

1.   469,135 shares of common stock of the
      Portfolio which had been registered under 
      the Securities Act other than pursuant to
      Rule 24f-2 remained unsold at the beginning 
      of the Fiscal Year.

2.   2,841,042 shares of common stock of the
     Portfolio were registered under the Securities
     Act during the Fiscal Year other than pursuant
     to Rule 24f-2.

3.   1,708,079 shares of common stock of the
      Portfolio were sold during the Fiscal Year.***
     
4.   No shares of common stock of the Portfolio
      were sold during the Fiscal Year in reliance 
      upon registration pursuant to Rule 24f-2.
     
_______________
*The aggregate sale price of all shares of Money
Reserve Portfolio Common stock sold during the
Fiscal Year was $159,076,741.

**The aggregate sale price of all shares of
Intermediate Government Bond Portfolio Common
Stock sold during the Fiscal Year was $29,374,025.

***The aggregate sale price of all shares of Long
Term Corporate Bond Portfolio Common Stock sold
during the Fiscal Year was $21,180,076.

<PAGE>

IV.  Capital Stock Portfolio Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the Securities
      Act other than pursuant to Rule 24f-2 remained
     unsold at the beginning of the Fiscal Year.

2.   951,170 shares of common stock of the
      Portfolio were registered under the Securities
      Act during the Fiscal Year other than
      pursuant to Rule  24f-2.

3.   2,648,003 shares of common stock of the
     Portfolio were sold during the Fiscal Year.*

4.   1,696,833 shares of common stock of the
      Portfolio were sold during the Fiscal Year
      in reliance upon registration pursuant to
      Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel for the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   Since the aggregate sale price of securities
      sold during the Fiscal Year in reliance upon
     registration pursuant to Rule 24f-2 is less
     than the aggregate redemption price of
     securities redeemed during the Fiscal Year,
     no filing fee is required in connection with 
     the filing of this Notice.  This calculation
     is as follows:
     
     (i)  Maximum possible sale price
         for the 1,696,833 shares of
         common stock of the Portfolio
         sold during the Fiscal Year
         in reliance upon registration
         pursuant to Rule 24f-2 (based on
         a maximum offering price during
         the Fiscal Year of $25.73).
                                                $43,659,513
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 3,146,632 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.
                                               $73,358,694
         
     equals amount on which filing fee
     is based.                          $   -0-

_______________
*The aggregate sale price of all shares of Capital
Stock Portfolio Common Stock sold during the
Fiscal Year was $61,600,014.

<PAGE>

V.   Growth Stock Portfolio Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the
      Securities Act other than pursuant to
      Rule 24f-2 remained unsold at the beginning 
      of the Fiscal Year.

2.   No shares of common stock of the Portfolio
      were registered under the Securities Act
      during the Fiscal Year other than pursuant
      to Rule 24f-2.

3.   2,765,508 shares of common stock of the
     Portfolio were sold during the Fiscal Year.*

4.   2,765,508 shares of common stock of the
      Portfolio were sold during the Fiscal Year
      in reliance upon registration pursuant to 
      Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel for the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   Since the aggregate sale price of securities
      sold during the Fiscal Year in reliance upon
     registration pursuant to Rule 24f-2 is less
     than the aggregate redemption price of
     securities redeemed during the Fiscal Year,
     no filing fee is required in connection with 
     the filing of this Notice.  This calculation is 
     as follows:
     
     (i)  Actual aggregate sale price
         for the 2,765,508 shares of
         common stock of the Portfolio
         sold during the Fiscal Year
         in reliance upon registration
         pursuant to Rule 24f-2   .

                                                $63,963,922
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 3,907,138 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.

                                               $90,314,726
         
     equals amount on which filing fee
     is based.                          $   -0-
     
_______________
*The aggregate sale price of all shares of Growth
Stock Portfolio Common Stock sold during the
Fiscal Year Was $63,963,922.
<PAGE>


VI.  Multiple Strategy Portfolio Common Stock

1.   75,174,745 shares of common stock of the
      Portfolio which had been registered under the
      Securities Act other than pursuant to Rule
      24f-2 remained unsold at the beginning of the
      Fiscal Year.

2.   5,182,735 shares of common stock of the
      Portfolio were registered under the Securities 
     Act during the Fiscal Year other than pursuant
     to Rule 24f-2.

3.   1,154,463 shares of common stock of the
      Portfolio were sold during the Fiscal Year.*

4.   No shares of common stock of the Portfolio
      were sold  during the Fiscal Year in reliance 
      upon registration pursuant to Rule 24f-2.


VII. High Yield Portfolio Common Stock

1.   No shares of common stock of the Portfolio
     which had been registered under the 
     Securities Act other than pursuant to 
     Rule 24f-2 remained unsold at the beginning 
     of the Fiscal Year.

2.   3,980,964 shares of common stock of the
     Portfolio were registered under the Securities
     Act during the Fiscal Year other than pursuant 
     to Rule 24f-2.

3.   6,585,394 shares of common stock of the
     Portfolio were sold during the Fiscal Year.**

4.   2,604,430 shares of common stock of the
      Portfolio were sold during the Fiscal Year
      in reliance upon registration pursuant to 
      Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel for the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   Since the aggregate sale price of securities
      sold during the Fiscal Year in reliance upon
     registration pursuant to Rule 24f-2 is less
     than the aggregate redemption price of
     securities redeemed during the Fiscal Year,
          
_______________
     *The aggregate sale price of all shares of
     Multiple Strategy Portfolio Common Stock sold
     during the Fiscal Year was $21,097,665.
     **The aggregate sale price of all shares of
     High Yield Portfolio Common Stock sold during
     the Fiscal Year was $62,046,849.
<PAGE>

     no filing fee is required in connection with the
     filing of this Notice.  This calculation is
     as follows:
     
     (i)  Maximum possible sale price
         for the 2,604,430 shares of
         common stock of the Portfolio
         sold during the Fiscal Year
         in reliance upon registration
         pursuant to Rule 24f-2.

                                             $25,210,882
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 5,176,485 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.

                                              $48,772,584
         
     equals amount on which filing fee
     is based.                          $   -0-


VIII.    Natural Resources Portfolio Common Stock

1.   751,279 shares of common stock of the
      Portfolio which had been registered under 
      the Securities Act other than pursuant to
      Rule 24f-2 remained unsold at the
      beginning of the Fiscal Year.

2.   1,151,819 shares of common stock of the
      Portfolio were registered  under the
      Securities Act during the Fiscal Year 
      other than pursuant to Rule 24f-2.

3.   4,270,081 shares of common stock of the
      Portfolio were sold during the Fiscal Year.*

4.   2,366,983 shares of common stock of the
      Portfolio were sold during the Fiscal Year
      in reliance upon registration pursuant to 
      Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel to the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   Since the aggregate sale price of securities
     sold during the Fiscal Year in reliance upon
     registration pursuant to Rule 24f-2 is less
     than the aggregate redemption price of
     securities redeemed during the Fiscal Year,
     no filing fee is required in connection with
     the filing of this Notice.
     
_______________
*The aggregate sale price of all shares of Natural
Resources Portfolio Common Stock sold during the
Fiscal Year was $33,052,306.
 <PAGE>
         
  This calculation is as follows:
     
     (i)  Maximum possible sale price
         for the 2,366,983 shares of
         common stock of the Portfolio
         sold during the Fiscal Year
         in reliance upon registration
         pursuant to Rule 24f-2   .

                                           $19,574,949
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 3,013,454 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.

                                          $23,296,035
         
     equals amount on which filing fee
     is based.                          $   -0-


IX.  Global Strategy Portfolio Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the 
      Securities Act other than pursuant to
      Rule 24f-2 remained unsold at the beginning
      of the Fiscal Year.

2.   No shares of common stock of the Portfolio
      were registered under the Securities Act during
     the Fiscal Year other than pursuant to Rule
     24f-2.

3.   9,185,981 shares of common stock of the
      Portfolio were sold during the Fiscal Year.*

4.   9,185,981 shares of common stock of the
      Portfolio were sold during the Fiscal Year
      in reliance upon registration pursuant to 
      Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel to the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   In accordance with Paragraph (c) of 
      Rule 24f-2, the fee of $38,267.97 has
      been wired.  Such fee which relates to 
      the 9,185,981 shares referred to in 
      Paragraph 4, is based upon the
      actual aggregate offering price for shares of
      the Portfolio during the Fiscal Year, reduced
      by the actual aggregate redemption or
      repurchase price of shares of the common
      stock of the Portfolio redeemed or
      repurchased during the Fiscal Year.  
_______________
*The aggregate sale price of all shares of Global
Strategy Portfolio Common Stock sold during the
Fiscal Year was $133,326,793.  All such shares
were sold in reliance upon registration pursuant
to Rule 24f-2.

<PAGE>

     The calculation of the amount on which the filing 
     fee is based as  follows:
     
     (i) Actual aggregate sale price
         for the 9,185,981 shares of
         common stock of the Portfolio
         sold during the Fiscal Year in
         reliance upon registration
         pursuant to Rule 24f-2.

                                          $133,326,793
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 1,577,997 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.

                                          $ 22,350,465
         
     equals amount on which filing fee
     is based.

                                          $110,976,328
     
Based on the above calculation, $38,267.97 is
payable with respect to the registration of shares
of Global Strategy Portfolio Common Stock.


X.   Balanced Portfolio Common Stock

1.   No shares of common stock of the Portfolio
      which had been registered under the 
     Securities Act other than pursuant to 
     Rule 24f-2 remained unsold at the beginning 
     of the Fiscal Year.

2.   No shares of common stock of the Portfolio
      were registered under the Securities Act during
     the Fiscal Year other than pursuant to Rule
     24f-2.

3.   2,187,445 shares of common stock of the
     Portfolio were sold during the Fiscal Year.*

4.   2,187,445 shares of common stock of the
     Portfolio were sold during the Fiscal Year 
     in reliance upon registration pursuant to 
     Rule 24f-2.

     Transmitted with this Notice is an opinion of
     Rogers & Wells, counsel for the Fund,
     indicating that the securities the
     registration of which this Notice makes
     definite in number were legally issued, fully
     paid and non-assessable.

5.   In accordance with Paragraph (c) of 
      Rule 24f-2, the fee of $7,876.19 has been 
      wired.  Such fee which relates to the 
      2,187,445 shares referred to in Paragraph
      4, is based upon the actual aggregate offering
      price for shares of the Portfolio during the 
      Fiscal Year, reduced by the actual aggregate 
      redemption or repurchase price of shares 
      of the common stock of the Portfolio redeemed
     
_______________
*The aggregate sale price of all shares of
Balanced Portfolio Common Stock sold during the
Fiscal year was $30,842,401.  

<PAGE>

     or repurchased during the Fiscal Year.  
     The Fund did not apply the redemption or 
     repurchase price of any shares of common 
     stock of the Portfolio redeemed or repurchased 
     during the Fiscal Year pursuant to Rule 
     24e-2(a) in filings made pursuant to Section 
     24(e)(1) of  the Investment Company Act of 
     1940.  The calculation of the amount on which 
     the filing fee is based as  follows:
     
     (i) Actual aggregate sale price
         for the 2,187,445 shares of
         common stock of the Portfolio
         sold during the Fiscal Year in
         reliance upon registration
         pursuant to Rule 24f-2.

                                                       $30,842,401
         
     reduced by
     
     (ii) Actual aggregate redemption
         price of 567,022 shares of
         common stock of the Portfolio
         redeemed during the Fiscal Year.  

                                                    $   8,001,609
         
     equals amount on which filing fee
     is based.

                                                     $22,840,792
     
Based on the above calculation, $7,876.19 is
payable with respect to the registration of shares
of Balanced Portfolio Common Stock Portfolio.

Please direct any questions relating to this
filing to Michael J. Hennewinkel at Merrill Lynch
Asset Management, P.O. Box 9011, Princeton, N.J.
08543-9011, (609) 282-2024, or Leonard B. Mackey
Jr. at Rogers & Wells, 200 Park Avenue, New York,
New York  10166, (212) 878-8000.

Very truly yours,

MERRILL LYNCH SERIES FUND, INC.




By /s/ Michael J. Hennewinkel
   - - - - - - - - - - - - - - -
     Michael J. Hennewinkel
          Secretary






ACC0F60F.WP5


                  [Rogers & Wells Letterhead]


                                    February 25, 1994



Merrill Lynch Series Fund, Inc.
800 Scudders Mill Road
Plainsboro, New Jersey 08536

Gentlemen:

             We  have  acted as counsel to Merrill  Lynch
Series Fund,   Inc.  (the  "Fund")  in  connection  with 
the  sale   of 192,052,276  shares of common stock, 
par value  $0.10  per  share (the  "Common  Stock"), 
of the Fund pursuant to the  Distribution Agreement 
between the Fund and Merrill Lynch Funds  Distributor,
Inc.  (the  "Distribution Agreement").   You  have  asked 
us  to furnish certain legal opinions in connection 
with the filing of a notice  (the "Notice") under Rule 24f-2
of the Investment Company Act of 1940, as 
amended (the "Act").

             For  purposes  of  the opinions  expressed  
in  this letter,  we  have  examined  the Articles  of  
Incorporation,  as amended  through the date hereof,
the Distribution Agreement  and such  other  documents
and questions of law  as  we  have  deemed necessary 
or  advisable.  As to relevant  matters  of  fact  not
independently   established,   we   have   relied    
upon    such representations, certificates, and other
documents as  we  deemed appropriate.

             Based  on the foregoing, we are of the 
opinion  that when  (a)  the  1,696,833  shares of 
the  Fund's  Capital  Stock Portfolio Common Stock 
referred to in paragraph 4 of Part  IV  of the  Notice;
(b) the 2,765,508 shares of the Fund's Growth  Stock
Portfolio  Common Stock referred to in paragraph 4 
of Part  V  of the  Notice;  (c) the 2,604,430 shares 
of the Fund's  High  Yield Portfolio Common Stock 
referred to in paragraph 4 of Part VII  of the  Notice; 
(d)  the  2,366,983 shares of  the  Fund's  Natural
Resources  Portfolio Common Stock referred to in 
paragraph  4  of Part  VIII of the Notice; (e) the
9,185,981 shares of the  Fund's Global Strategy 
Portfolio Common Stock referred to in paragraph 4
of  Part  IX of the Notice; and (f) the 2,187,445 
shares  of  the Fund's Balanced Portfolio Common 
Stock referred to in paragraph 4 of  Part  X of the
Notice were sold during the fiscal year  ended
December  31,  1993  pursuant to the  Distribution 
Agreement  in reliance upon registration pursuant
to Rule 24f-2 of the Act  and in  accordance  with
the currently effective  prospectus  of  the
Fund,  the shares referred to in clauses (a),
(b), (c), (d),  (e) and (f) were legally issued, fully
paid and non-assessable.

                                    Very truly yours,


                                    /s/ Rogers & Wells



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