MERRILL LYNCH SERIES FUND INC
497, 1995-11-27
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               SUPPLEMENT DATED NOVEMBER 28, 1995
             TO THE PROSPECTUS DATED APRIL 21, 1995
                               FOR
                 MERRILL LYNCH SERIES FUND, INC.


     The disclosure appearing under the caption "Investment
Adviser" is amended by replacing the fifth, sixth and eleventh
paragraphs in their entirety with the following:

     Effective November 1, 1995, Thomas R. Robinson is responsible
for the day-to-day management of Balanced Portfolio, Capital Stock
Portfolio, Global Strategy Portfolio and Multiple Strategy
Portfolio.  Mr. Robinson has been a Senior Portfolio Manager of the
Company since 1995.  Prior thereto, Mr. Robinson was employed by
Merrill Lynch & Co.'s Global Securities Research & Economics Group
where he served as Manager of International Equity Strategy from
1989 to 1995.


			      
                              16586, 16587, 16116-KIT, 16117-KIT,
                              16142-KIT, 16145-KIT

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